Research Explorer

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Researcher

Jan Van Deun

Awards & Distinctions

33 Results

2020

Feasibility of mechanical extrusion to coat nanoparticles with extracellular vesicle membranes

Jan Van DeunQuentin RouxSarah DevilleThibaut Van AckerPekka RappuIlkka MiinalainenJyrki HeinoFrank VanhaeckeBruno De GeestOlivier De Wever et al.

A1 Journal Article in CELLS

Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction

Joeri TulkensGlenn VergauwenJan Van DeunEdward GeeurickxBert DhondtLien LippensMarie-Angélique De ScheerderIlkka MiinalainenPekka RappuBruno De Geest et al.

A1 Journal Article in GUT

Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine

Bert DhondtEdward GeeurickxJoeri TulkensJan Van DeunGlenn VergauwenLien LippensIlkka MiinalainenPekka RappuJyrki HeinoPiet Ost et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

2019

Exploration of the urinary proteome in the search for new biomarkers for prostate cancer : a promising role for extracellular vesicles

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxLien LippensJoeri Tulkenslkka MiinalainenPekka RappuJyrki Heino Oulu, FinlandPiet Ost et al.

Stromal integrin α11 regulates PDGFRβ signaling and promotes breast cancer progression

Irina PrimacErik MaquoiSilvia BlacherRitva HeljasvaaraJan Van DeunHilde YH SmelandAnnalisa CanaleThomas LouisLinda StuhrNor Eddine Sounni et al.

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

The generation and use of recombinant extracellular vesicles as biological reference material

Edward GeeurickxJoeri TulkensBert DhondtJan Van DeunLien LippensGlenn VergauwenElisa HeyrmanDelphine De SutterKris GevaertFrancis Impens et al.

A1 Journal Article in NATURE COMMUNICATIONS

Vesiclepedia 2019 : a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles

Mohashin PathanPamali FonsekaSai V ChittiTaeyoung KangRahul SanwlaniJan Van DeunAn HendrixSuresh Mathivanan

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2018

Bursting the bubble : introducing rigor in extracellular vesicle research to track and target cancer

Jan Van DeunOlivier De WeverAn Hendrix

Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde ThéryKenneth W WitwerElena AikawaMaria Jose AlcarazJohnathon D AndersonRamaroson AndriantsitohainaAnna AntoniouTanina ArabFabienne ArcherGeorgia K Atkin-Smith et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxElisa HeyrmanJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensIlkka Miinalainen et al.

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxElisa HeyrmanJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensIlkka Miinalainen et al.

Repeatable, high-purity isolation of urinary extracellular vesicles for uro-oncological biomarker studies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensIlkka MiinalainenPekka RappuJyrki HeinoNicolaas Lumen et al.

Reproduceerbare isolatie van hoog-zuivere urinaire extracellulaire vesikels voor uro-oncologische biomerkerstudies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensSarah BuelensElise De BleserFilip PoelaertTom Claeys et al.

Reproducible high-purity isolation of urinary extracellular vesicles for uro-oncological biomarker studies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensSarah BuelensElise De BleserIlkka MiinalainenPekka Rappu et al.

Reproducible isolation of high-purity urinary extracellular vesicles for uro-oncological biomarker studies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensSarah BuelensElise De BleserFilip PoelaertTom Claeys et al.

Transparent reporting of experimental parameters in assays measuring phenotypic steps in metastasis

Robin BoiyJonas SteenbruggeJan Van DeunAn HendrixEvelyne MeyerOlivier De Wever

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

Urinary extracellular vesicle biomarkers in urological cancers : from discovery towards clinical implementation

Bert DhondtJan Van DeunSilke VermaerkeArio de MarcoNicolaas LumenOlivier De WeverAn Hendrix

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

2017

Confounding factors in extracellular vesicle ultrafiltration and protein analysis

Glenn VergauwenBert DhondtJan Van DeunEvy TimmermanKris GevaertGeert BraemsRudy Van den BroeckeVeronique CocquytHannelore DenysOlivier De Wever et al.

Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research

Glenn VergauwenBert DhondtJan Van DeunEva De SmedtGeert BerxEvy TimmermanKris GevaertIlkka MiinalainenVeronique CocquytGeert Braems et al.

A1 Journal Article in SCIENTIFIC REPORTS

EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research

Jan Van DeunPieter MestdaghPatrizia AgostinisÖzden AkaySushma AnandJasper AnckaertZoraida Andreu MartinezTine BaetensEls BegheinLaurence Bertier et al.

A1 Journal Article in NATURE METHODS

Identification of confounding factors of EV isolation and protein analysis

Glenn VergauwenBert DhondtJan Van DeunEvy TimmermanKris GevaertVeronique CocquytGeert BraemsRudy Van den BroeckeHannelore DenysOlivier De Wever et al.

Is your article EV-TRACKed?

Jan Van DeunAn Hendrix

Editorial material

Purification of urinary extracellular vesicles for uro-oncological biomarker studies using an iodixanol (OptiprepTM) density gradient

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxTom ClaeysFilip PoelaertSarah BuelensNicolaas LumenAn HendrixOlivier De Wever

Purification of urinary extracellular vesicles for uro-oncological biomarker studies using an iodixanol (Optiprep™) density gradient

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxTom ClaeysFilip PoelaertSarah BuelensAn HendrixOlivier De WeverNicolaas Lumen

The isolation of morphologically intact and biologically active extracellular vesicles from the secretome of cancer-associated adipose tissue

Sarah JeurissenGlenn VergauwenJan Van DeunLore LapeireVictoria DepoorterIlkka MiinalainenRaija SormunenRudy Van den BroeckeGeert BraemsVeronique Cocquyt et al.

A1 Journal Article in CELL ADHESION & MIGRATION

2016

EV-TRAQ: tracking transparent reporting and quality to boost standardized extracellular vesicle research

Jan Van DeunPieter MestdaghJasper AnckaertJo VandesompeleOlivier De WeverAn Hendrix

Isolation of urinary extracellular vesicles for uro-oncological biomarker studies is complicated by Tamm-Horsfall protein

Bert DhondtDelphine DavelooseGlenn VergauwenJan Van DeunEdward GeeurickxTom ClaeysFilip PoelaertAn HendrixOlivier De WeverNicolaas Lumen

Mapping the methodological diversity of EV isolation and characterization

Jan Van DeunPieter MestdaghJo VandesompeleOlivier De WeverAn Hendrix

Recent exposure to ultrafine particles in school children alters miR-222 expression in the extracellular fraction of saliva

Annette VriensTim S NawrotNelly D SaenenEline B ProvostMichal KicinskiWouter LefebvreCharlotte VanpouckeJan Van DeunOlivier De WeverKaren Vrijens et al.

A1 Journal Article in ENVIRONMENTAL HEALTH

Transiently responsive block copolymer micelles based on N-(2-hydroxypropyl)methacrylamide engineered with hydrolyzable ethylcarbonate side chains

Sabah KasmiBenoit LouageLutz NuhnAlexandra Van DriesscheJan Van DeunIzet KaralicMartijn RisseeuwSerge Van CalenberghRichard HoogenboomRiet De Rycke et al.

A1 Journal Article in BIOMACROMOLECULES

2015

Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade

Ijeoma Adaku UmeloOlivier De WeverPeter KronenbergerJan Van DeunAlfiah NoorKshitiz SinghErik TeugelsGang ChenMarc BrackeJacques De Grève

A1 Journal Article in ONCOTARGET

2014

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Jan Van DeunPieter MestdaghRaija SormunenLotte PyfferoenKarim VermaelenVeronique CocquytJo VandesompeleMarc BrackeOlivier De WeverAn Hendrix

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Jan Van DeunPieter MestdaghRaija SormunenVeronique CocquytKarim VermaelenJo VandesompeleMarc BrackeOlivier De WeverAn Hendrix

A2 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES