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Researcher
Jan Van Bocxlaer
Profile
Projects
Publications
Activities
208
Results
2021
Physiologically based pharmacokinetic modelling of lisinopril in children: A case story of angiotensin converting enzyme inhibitors
Feifan Xie
Jan Van Bocxlaer
An Vermeulen
A1
Journal Article
in
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
2021
2020
An integrated paediatric population PK/PD analysis of dDAVP : how do PK differences translate to clinical outcomes?
Robin Michelet
Lien Dossche
Charlotte Van Herzeele
Pauline De Bruyne
Elke Gasthuys
Jan Van Bocxlaer
Johan Vande Walle
An Vermeulen
A1
Journal Article
in
CLINICAL PHARMACOKINETICS
2020
Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma
Elien De Thaye
Koen Van de Vijver
Joni Van der Meulen
Joachim Taminau
Glenn Wagemans
Hannelore Denys
Jo Van Dorpe
Geert Berx
Wim Ceelen
Jan Van Bocxlaer
Olivier De Wever
A1
Journal Article
in
SCIENTIFIC REPORTS
2020
Exploration of more personalized treatments in ovarian cancer using a pharmacodynamic protein biomarker and patient-derived xenograft technology
Elien De Thaye
Jan Van Bocxlaer
An Vermeulen
Pieter Colin
Dissertation
2020
PKPD modeling and dosing considerations in advanced ovarian cancer patients treated with cisplatin-based intraoperative intraperitoneal chemotherapy
Feifan Xie
Jan Van Bocxlaer
Pieter Colin
Charlotte Carlier
Olivier Van Kerschaver
Joseph Weerts
Hannelore Denys
Philippe Tummers
Wouter Willaert
Wim Ceelen
An Vermeulen
A1
Journal Article
in
AAPS JOURNAL
2020
Pediatric pharmacology of desmopressin in children with enuresis : a comprehensive review
Elke Gasthuys
Lien Dossche
Robin Michelet
Jens Peter Norgaard
Mathias Devreese
Siska Croubels
An Vermeulen
Jan Van Bocxlaer
Johan Vande Walle
A1
Journal Article
in
PEDIATRIC DRUGS
2020
Pharmacokinetics in patients with cystic fibrosis : a systematic review of data published between 1999 and 2019
Pieter-Jan De Sutter
Elke Gasthuys
Eva Van Braeckel
Petra Schelstraete
Stephanie Van Biervliet
Jan Van Bocxlaer
An Vermeulen
A1
Journal Article
in
CLINICAL PHARMACOKINETICS
2020
Target-controlled infusion of cefepime in critically Ill patients
Stijn Jonckheere
Nikolaas De Neve
Jan Verbeke
Koen De Decker
Inger Brandt
An Boel
Jan Van Bocxlaer
Michel Struys
Pieter J. Colin
A1
Journal Article
in
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2020
2019
Bioanalysis and model based treatment optimization for preclinical and clinical studies of peritoneal carcinomatosis from ovarian cancer
Feifan Xie
Jan Van Bocxlaer
An Vermeulen
Pieter Colin
Dissertation
2019
Characterization of porcine hepatic and intestinal drug metabolizing CYP450 : comparison with human orthologues from a quantitative, activity and selectivity perspective
Wim Schelstraete
Laura De Clerck
Elisabeth Govaert
Joske Millecam
Mathias Devreese
Dieter Deforce
Jan Van Bocxlaer
Siska Croubels
A1
Journal Article
in
SCIENTIFIC REPORTS
2019
Model-based analysis of treatment effects of paclitaxel microspheres in a microscopic peritoneal carcinomatosis model in mice.
Feifan Xie
Kaat De Clercq
Chris Vervaet
Jan Van Bocxlaer
Pieter Colin
An Vermeulen
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2019
PBPK and its virtual populations : the impact of physiology on pediatric pharmacokinetic predictions of tramadol
Huybrecht T'jollyn
An Vermeulen
Jan Van Bocxlaer
A1
Journal Article
in
AAPS JOURNAL
2019
Pharmacodynamic interaction of remifentanil and dexmedetomidine on depth of sedation and tolerance of laryngoscopy
Maud A. S. Weerink
Clemens R. M. Barends
Ernesto R. R. Muskiet
Koen M. E. M. Reyntjens
Froukje H. Knotnerus
Martine Oostra
Jan Van Bocxlaer
Michel Struys
Pieter Colin
A1
Journal Article
in
ANESTHESIOLOGY
2019
Pharmacokinetic evaluation of linezolid administered intravenously in obese patients with pneumonia
Feifan Xie
Konstantinos Mantzarlis
Polychronis Malliotakis
Vasileios Koulouras
Sophie Degroote
Despoina Koulenti
Stijn Blot
Koen Boussery
Jan Van Bocxlaer
Pieter Colin
A1
Journal Article
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2019
Switchability of gabapentin formulations : a randomized trial to assess bioequivalence between Neurontin and Gabasandoz on the individual subject level
Griet Van Lancker
Lucas Van Bortel
Brant Delafontaine
Koen Boussery
Eleonora Swart
Abdel Chahbouni
Jan Van Bocxlaer
Pieter Colin
A1
Journal Article
in
CLINICAL PHARMACOLOGY & THERAPEUTICS
2019
2018
A dried blood spot assay for paclitaxel and its metabolites
Feifan Xie
Elien De Thaye
An Vermeulen
Jan Van Bocxlaer
Pieter Colin
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2018
A model-based analysis of the kinetics of leukocytes in stage III ovarian cancer patients treated with neo-adjuvant chemotherapy, cytoreductive surgery and cisplatin-based intraperitoneal chemoperfusion
Feifan Xie
Charlotte Carlier
Wim Ceelen
Jan Van Bocxlaer
An Vermeulen
Pieter Colin
C3
Conference
2018
A physiologically based pharmacokinetic perspective on the clinical utility of albumin-based dose adjustments in critically ill patients
Huybrecht T'jollyn
An Vermeulen
Jan Van Bocxlaer
Pieter Colin
A1
Journal Article
in
CLINICAL PHARMACOKINETICS
2018
Claiming desmopressin therapeutic equivalence in children requires pediatric data : a population PKPD analysis
Robin Michelet
Lien Dossche
Charlotte Van Herzeele
Jan Van Bocxlaer
An Vermeulen
Johan Vande Walle
A1
Journal Article
in
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
2018
Maturation of hepatic cytochrome P450 enzymes in conventional pigs : fact or fiction?
Joske Millecam
Laura De Clerck
Elisabeth Govaert
Mathias Devreese
Elke Gasthuys
Wim Schelstraete
Dieter Deforce
Lies De Bock
Jan Van Bocxlaer
Stanislas Sys
Siska Croubels
C3
Conference
2018
Maturation of hepatic cytochrome P450 enzymes in conventional pigs : the added value of proteomics
Joske Millecam
Laura De Clerck
Elisabeth Govaert
Mathias Devreese
Elke Gasthuys
Wim Schelstraete
Dieter Deforce
Lies De Bock
Jan Van Bocxlaer
Stanislas Sys
Siska Croubels
C3
Conference
2018
Maturation of hepatic cytochrome P450 enzymes in conventional pigs as model for preclinical paediatric drug research
Joske Millecam
Laura De Clerck
Elisabeth Govaert
Mathias Devreese
Elke Gasthuys
Wim Schelstraete
Dieter Deforce
Lies De Bock
Jan Van Bocxlaer
Stanislas Sys
Siska Croubels
C3
Conference
2018
Prediction of pediatric pharmacokinetics to optimize dose regimens using bottom-up, top-down and middle-out approaches
Robin Michelet
An Vermeulen
Jan Van Bocxlaer
Dissertation
2018
Results of a multicenter population pharmacokinetic study of ciprofloxacin in children with complicated urinary tract infection
Kevin Meesters
Robin Michelet
REINER MAUEL
Ann Raes
Jan Van Bocxlaer
Johan Vande Walle
An Vermeulen
A1
Journal Article
in
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2018
The ontogeny of cytochrome P450 enzyme activity and protein abundance in conventional pigs in support of preclinical pediatric drug research
Joske Millecam
Laura De Clerck
Elisabeth Govaert
Mathias Devreese
Elke Gasthuys
Wim Schelstraete
Dieter Deforce
Lies De Bock
Jan Van Bocxlaer
Stanislas Sys
Siska Croubels
A1
Journal Article
in
FRONTIERS IN PHARMACOLOGY
2018
The use of PBPK modeling across the pediatric age range using propofol as a case
Robin Michelet
Jan Van Bocxlaer
Karel Allegaert
An Vermeulen
A1
Journal Article
in
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
2018
2017
A new approach in pediatric drug design : the development of a pediatric pig model, part II : the maturation of hepatic cytochrome P450 enzymes using enzyme activity and proteomics
Joske Millecam
Elke Gasthuys
Mathias Devreese
Dieter Deforce
Lies De Bock
Jan Van Bocxlaer
Siska Croubels
C3
Conference
2017
Electrospray ionization mass spectrometry for the hydrolysis complexes of cisplatin : implications for the hydrolysis process of platinum complexes
Feifan Xie
Pieter Colin
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF MASS SPECTROMETRY
2017
PBPK in preterm and term neonates : a review
Robin Michelet
Jan Van Bocxlaer
An Vermeulen
A1
Journal Article
in
CURRENT PHARMACEUTICAL DESIGN
2017
Paediatric PBPK modelling of propofol using the middle out approach
Robin Michelet
Jan Van Bocxlaer
An Vermeulen
C3
Conference
2017
Pharmacokinetic analysis of modified-release metoprolol formulations : an interspecies comparison
Elien De Thaye
Anouk Vervaeck
Eleonora Marostica
Jean Paul Remon
Jan Van Bocxlaer
Chris Vervaet
An Vermeulen
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
2017
Strategies for determining correct cytochrome P450 contributions in hepatic clearance predictions : in vitro-in vivo extrapolation as modelling approach and tramadol as proof-of concept compound
Huybrecht T'jollyn
Jan Snoeys
Jan Van Bocxlaer
Lies De Bock
Pieter Annaert
Achiel Van Peer
Karel Allegaert
Geert Mannens
An Vermeulen
Koen Boussery
A1
Journal Article
in
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
2017
The ontogeny of hepatic cytochrome P450 enzymes in conventional pigs using enzyme activity and proteomics
Joske Millecam
Elke Gasthuys
Mathias Devreese
Dieter Deforce
Jan Van Bocxlaer
Siska Croubels
C3
Conference
2017
Zwitterionic hydrophilic interaction liquid chromatography-tandem mass spectrometry with HybridSPE-precipitation for the determination of intact cisplatin in human plasma
Feifan Xie
Pieter Colin
Jan Van Bocxlaer
A1
Journal Article
in
TALANTA
2017
2016
A model-based analysis of the predictive performance of different renal function markers for cefepime clearance in the ICU
Stijn Jonckheere
Nikolaas De Neve
Hans De Beenhouwer
Mario Berth
An Vermeulen
Jan Van Bocxlaer
Pieter Colin
A1
Journal Article
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2016
Antimicrobial effect of a single dose of amoxicillin on the oral microbiota
Cecilia Larsson Wexell
Henrik Ryberg
Wivi-Anne Sjöberg Andersson
Susanne Blomqvist
Pieter Colin
Jan Van Bocxlaer
Gunnar Dahlén
A1
Journal Article
in
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
2016
Bioequivalence in adults does not mean bioequivalence in children
Lien Dossche
Robin Michelet
Pauline De Bruyne
Jan Van Bocxlaer
An Vermeulen
Johan Vande Walle
C3
Conference
2016
Bioequivalence in adults is not always bioequivalence in children
Lien Dossche
Ann Raes
Pauline De Bruyne
Robin Michelet
An Vermeulen
Jan Van Bocxlaer
Johan Vande Walle
C3
Conference
2016
Characterizing hepatic clearance in early life : PBPK as modelling tool and tramadol as guide
Huybrecht T'jollyn
Jan Van Bocxlaer
An Vermeulen
Koen Boussery
Dissertation
2016
Disulfiram inhibition of cyanide formation after acetonitrile poisoning
Peter De Paepe
Pieter Colin
Pieter Depuydt
An-Sofie Decavele
Julie De Smet
Koen Boussery
Christophe Stove
Dominique Benoit
Alain Verstraete
Jan Van Bocxlaer
Walter Buylaert
A1
Journal Article
in
CLINICAL TOXICOLOGY
2016
Drug administration via enteral feeding tube in residential care facilities for individuals with intellectual disability : a focus group study on guideline implementation
Elke Joos
Inge Van Tongelen
Karen Wijnants
Els Mehuys
Jan Van Bocxlaer
Jean Paul Remon
Maria Grypdonck
Myriam Van Winckel
Koen Boussery
A2
Journal Article
in
JOURNAL OF INTELLECTUAL DISABILITIES
2016
Effect of food and pharmaceutical formulation on desmopressin pharmacokinetics in children
Robin Michelet
Lien Dossche
Pauline De Bruyne
Pieter Colin
Koen Boussery
Johan Vande Walle
Jan Van Bocxlaer
An Vermeulen
C3
Conference
2016
Effect of food and pharmaceutical formulation on desmopressin pharmacokinetics in children
Robin Michelet
Lien Dossche
Pauline De Bruyne
Pieter Colin
Koen Boussery
Johan Vande Walle
Jan Van Bocxlaer
An Vermeulen
C3
Conference
2016
Effects of food and pharmaceutical formulation on desmopressin pharmacokinetics in children
Robin Michelet
Lien Dossche
Pauline De Bruyne
Pieter Colin
Koen Boussery
Johan Vande Walle
Jan Van Bocxlaer
An Vermeulen
A1
Journal Article
in
CLINICAL PHARMACOKINETICS
2016
Interaction between Fusarium mycotoxins and cytochrome P450 drug metabolizing enzymes/ABC drug transporters in a porcine animal model
Wim Schelstraete
Mathias Devreese
Jan Van Bocxlaer
Siska Croubels
C3
Conference
2016
Knowledge of staff members of residential care facilities for individuals with intellectual disability on medication administration via enteral feeding tube
Elke Joos
Els Mehuys
Jan Van Bocxlaer
Jean Paul Remon
Myriam Van Winckel
Koen Boussery
A1
Journal Article
in
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH
2016
Medication administration via enteral feeding tube: a survey of pharmacists' knowledge
Elke Joos
Stacey Verbeke
Els Mehuys
Jan Van Bocxlaer
Jean Paul Remon
Myriam Van Winckel
Koen Boussery
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
2016
PK/PD modelling of the QT interval : a step towards defining the translational relationship between in vitro, awake Beagle dogs, and humans
Eleonora Marostica
Karel Van Ammel
Ard Teisman
David Gallacher
Jan Van Bocxlaer
Filip De Ridder
Koen Boussery
An Vermeulen
A1
Journal Article
in
AAPS JOURNAL
2016
What about confidence intervals? : a word of caution when interpreting PTA simulations
Pieter Colin
Douglas J Eleveld
Stijn Jonckheere
Jan Van Bocxlaer
Jan De Waele
An Vermeulen
A1
Journal Article
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2016
2015
Age-related differences in CYP3A abundance and activity in the liver of the Gottingen Minipig
Els Van Peer
Lies De Bock
Koen Boussery
Jan Van Bocxlaer
Christophe Casteleyn
Chris Van Ginneken
Steven Van Cruchten
A1
Journal Article
in
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
2015
Degradable ketal-based block copolymer nanoparticles for anticancer drug delivery : a systematic evaluation
Benoit Louage
Qilu Zhang
Nane Vanparijs
Lenny Voorhaar
Sofie Vande Casteele
Yang Shi
Wim E Hennink
Jan Van Bocxlaer
Richard Hoogenboom
Bruno De Geest
A1
Journal Article
in
BIOMACROMOLECULES
2015
Drug administration via enteral feeding tubes in residential care facilities for individuals with intellectual disability : an observational study
Elke Joos
Els Mehuys
Jan Van Bocxlaer
Jean Paul Remon
Myriam Van Winckel
Koen Boussery
A1
Journal Article
in
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH
2015
Hot-melt extrusion of polyvinyl alcohol for oral immediate release applications
Wesley De Jaeghere
Thomas De Beer
Jan Van Bocxlaer
Jean Paul Remon
Chris Vervaet
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2015
Modelling of drug-induced QT-interval prolongation: estimation approaches and translational opportunities
Eleonora Marostica
Karel Van Ammel
Ard Teisman
Koen Boussery
Jan Van Bocxlaer
Filip De Ridder
David Gallacher
An Vermeulen
A1
Journal Article
in
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
2015
Physiologically based pharmacokinetic predictions of tramadol exposure throughout pediatric life: an analysis of the different clearance contributors with emphasis on CYP2D6 maturation
Huybrecht T'jollyn
Jan Snoeys
An Vermeulen
Robin Michelet
Filip Cuykens
Geert Mannens
Achiel Van Peer
Pieter Annaert
Karel Allegaert
Jan Van Bocxlaer
Koen Boussery
A1
Journal Article
in
AAPS JOURNAL
2015
Physiology-based IVIVE predictions of tramadol from in vitro metabolism data
Huybrecht T'jollyn
Jan Snoeys
Pieter Colin
Jan Van Bocxlaer
Pieter Annaert
Filip Cuyckens
An Vermeulen
Achiel Van Peer
Karel Allegaert
Geert Mannens
Koen Boussery
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2015
The ontogeny of hepatic CYP3A, CYP2C and CYP2E enzyme activity in conventional pigs
Joske Millecam
Mathias Devreese
Lies De Bock
Jan Van Bocxlaer
Elke Gasthuys
Patrick De Backer
Siska Croubels
C3
Conference
2015
2014
A model based analysis of IPEC dosing of paclitaxel in rats
Pieter Colin
Lieselotte De Smet
Chris Vervaet
Jean Paul Remon
Wim Ceelen
Jan Van Bocxlaer
Koen Boussery
An Vermeulen
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2014
Disulfiram inhibition of cyanide formation after acetonitrile poisoning
Peter De Paepe
Pieter Colin
Pieter Depuydt
An-Sofie Decavele
Julie De Smet
Koen Boussery
Christophe Stove
DOMINIQUE BENOIT
Alain Verstraete
Jan Van Bocxlaer
Walter Buylaert
C3
Conference
2014
Enzymatic tumour tissue digestion coupled to SPE-UPLC–tandem mass spectrometry as a tool to explore paclitaxel tumour penetration
Pieter Colin
Lieselotte De Smet
Lies De Bock
Wim Goeteyn
Koen Boussery
Chris Vervaet
Jan Van Bocxlaer
A1
Journal Article
in
TALANTA
2014
Formulation of itraconazole nanococrystals and evaluation of their bioavailability in dogs
Lieselotte De Smet
Lien Saerens
Thomas De Beer
Robert Carleer
Peter Adriaensens
Jan Van Bocxlaer
Chris Vervaet
Jean Paul Remon
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2014
Medication management in Belgian residential care facilities for individuals with intellectual disability: an observational study
Elke Joos
Els Mehuys
Jan Van Bocxlaer
Jean Paul Remon
Myriam Van Winckel
Koen Boussery
A1
Journal Article
in
JOURNAL OF POLICY AND PRACTICE IN INTELLECTUAL DISABILITIES
2014
Microsomal protein per gram of liver (MPPGL) in paediatric biliary atresia patients
Lies De Bock
Koen Boussery
RUTH DE BRUYNE
Myriam Van Winckel
Xavier Stephenne
Etienne Sokal
Jan Van Bocxlaer
A1
Journal Article
in
BIOPHARMACEUTICS & DRUG DISPOSITION
2014
Moxifloxacin dosing in post-bariatric surgery patients
Pieter Colin
Douglas J Eleveld
Michel Struys
Huybrecht T'jollyn
Lucas Van Bortel
Johannes Ruige
Jan De Waele
Jan Van Bocxlaer
Koen Boussery
A1
Journal Article
in
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
2014
Pharmacokinetics in children with liver disease : can ex vivo obtained population-specific CYP450 characteristics bridge the knowledge gap?
Lies De Bock
Jan Van Bocxlaer
Koen Boussery
Dissertation
2014
Quantification of cytochrome 2E1 in human liver microsomes using a validated indirect ELISA
Lies De Bock
Pieter Colin
Koen Boussery
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2014
Towards model-based dose optimization of antibiotic and anti-cancer treatment regimens in specific patient populations
Pieter Colin
Jan Van Bocxlaer
Koen Boussery
An Vermeulen
Dissertation
2014
Untargeted screening of secondary metabolites in fungal cultures and samples from mouldy indoor environments by time-of-flight mass spectrometry
Svetlana Malysheva
Viviana Polizzi
Antonio Moretti
Carlos Van Peteghem
Norbert De Kimpe
Jan Van Bocxlaer
José Diana Di Mavungu
Sarah De Saeger
A1
Journal Article
in
WORLD MYCOTOXIN JOURNAL
2014
2013
Development and validation of a fast and uniform approach to quantify β-lactam antibiotics in human plasma by solid phase extraction-liquid chromatography-electrospray-tandem mass spectrometry
Pieter Colin
Lies De Bock
Huybrecht T'jollyn
Koen Boussery
Jan Van Bocxlaer
A1
Journal Article
in
TALANTA
2013
Formulation of poorly water-soluble drugs via coacervation : a pilot study using febantel
Wesley De Jaeghere
Bruno De Geest
Jan Van Bocxlaer
Jean Paul Remon
Chris Vervaet
Andre Antunes
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2013
Hepatic and intestinal CYP3A expression and activity in broilers
Ann Osselaere
Lies De Bock
Venessa Eeckhaut
Patrick De Backer
Jan Van Bocxlaer
Koen Boussery
Siska Croubels
A1
Journal Article
in
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
2013
In vitro cytochrome P450 activity decreases in children with high paediatric end-stage liver disease scores
Lies De Bock
Koen Boussery
Myriam Van Winckel
Peter De Paepe
Xavier Rogiers
Xavier Stephenne
Etienne Sokal
Jan Van Bocxlaer
A1
Journal Article
in
DRUG METABOLISM AND DISPOSITION
2013
Metabolism of hop-derived bitter acids
Ko Cattoor
Michael Dresel
Lies De Bock
Koen Boussery
Jan Van Bocxlaer
Jean Paul Remon
Denis De Keukeleire
Dieter Deforce
Thomas Hofmann
Arne Heyerick
A1
Journal Article
in
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
2013
The influence of bypass procedures and other anatomical changes in the gastrointestinal tract on the oral bioavailability of drugs
Julie De Smet
Jan Van Bocxlaer
Koen Boussery
A1
Journal Article
in
JOURNAL OF CLINICAL PHARMACOLOGY
2013
The mycotoxin T-2 inhibits hepatic cytochrome P4503A activity in pigs
Joline Goossens
Lies De Bock
Ann Osselaere
Elin Verbrugghe
Mathias Devreese
Koen Boussery
Jan Van Bocxlaer
Patrick De Backer
Siska Croubels
A1
Journal Article
in
FOOD AND CHEMICAL TOXICOLOGY
2013
Toxic effects of dietary exposure to T-2 toxin on intestinal and hepatic biotransformation enzymes and drug transporter systems in broiler chickens
Ann Osselaere
Shaoji Li
Lies De Bock
Mathias Devreese
Joline Goossens
Virginie Vandenbroucke
Jan Van Bocxlaer
Koen Boussery
Frank Pasmans
An Martel
Patrick De Backer
Siska Croubels
A1
Journal Article
in
FOOD AND CHEMICAL TOXICOLOGY
2013
2012
Analytical performance evaluation of four cartridge-type blood gas analyzers
ANNE-SOPHIE DE KONINCK
Koen De Decker
Jan Van Bocxlaer
Peter Meeus
Lieve Van Hoovels
A1
Journal Article
in
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
2012
Development and validation of a fast and sensitive UPLC-MS/MS method for the quantification of six probe metabolites for the in vitro determination of cytochrome P450 activity
Lies De Bock
Koen Boussery
Pieter Colin
Julie De Smet
Huybrecht T'jollyn
Jan Van Bocxlaer
A1
Journal Article
in
TALANTA
2012
Development and validation of an enzyme-linked immunosorbent assay for the quantification of cytochrome 3A4 in human liver microsomes
Lies De Bock
Pieter Colin
Koen Boussery
Jan Van Bocxlaer
A1
Journal Article
in
TALANTA
2012
Development of a nanocrystalline Paclitaxel formulation for HIPEC treatment
Lieselotte De Smet
Pieter Colin
Wim Ceelen
Marc Bracke
Jan Van Bocxlaer
Jean Paul Remon
Chris Vervaet
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2012
Flavonoid deactivation of excited state flavins: reaction monitoring by mass spectrometry
Kevin Huvaere
Bart Sinnaeve
Jan Van Bocxlaer
Leif H Skibsted
A1
Journal Article
in
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
2012
Hypervariable cytochrome P450 activity in children with severe hepatic dysfunction
Lies De Bock
Koen Boussery
Myriam Van Winckel
Peter De Paepe
Xavier Stephenne
Etienne Sokal
Jan Van Bocxlaer
C3
Conference
2012
Impact of corneal cross-linking on drug penetration in an ex vivo porcine eye model
Markus Tschopp
Johannes Stary
Beatrice E Frueh
Wolfgang Thormann
Julie De Smet
Jan Van Bocxlaer
Christoph Tappeiner
A1
Journal Article
in
CORNEA
2012
Oral bioavailability of moxifloxacin after Roux-en-Y gastric bypass surgery
Julie De Smet
Pieter Colin
Peter De Paepe
Johannes Ruige
Hélène Batens
Yves Van Nieuwenhove
Dirk Vogelaers
Stijn Blot
Jan Van Bocxlaer
Lucas Van Bortel
Koen Boussery
A1
Journal Article
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2012
Switch from intravenous to enteral moxifloxacin in critically ill patients: a pilot study
Julie De Smet
Kirsten Colpaert
Peter De Paepe
Jan Van Bocxlaer
Johan Decruyenaere
Koen Boussery
A1
Journal Article
in
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
2012
The impact of a changed anatomy of the gastrointestinal tract on the bioavailability of proton pump inhibitors and fluoroquinolone antibiotics
Julie De Smet
Jan Van Bocxlaer
Koen Boussery
Dissertation
2012
2011
An evaluation of using population pharmacokinetic models to estimate pharmacodynamic parameters for propofol and bispectral index in children
Marc Coppens
Douglas J Eleveld
Johannes H Proost
Luc Marks
Jan Van Bocxlaer
Hugo Vereecke
Anthony R Absalom
Michel Struys
A1
Journal Article
in
ANESTHESIOLOGY
2011
Bioavailability of hop-derived iso-α-acids and reduced derivatives
Ko Cattoor
Jean Paul Remon
Koen Boussery
Jan Van Bocxlaer
Marc Bracke
Denis De Keukeleire
Dieter Deforce
Arne Heyerick
A1
Journal Article
in
FOOD & FUNCTION
2011
Evaluation of three state-of-the-art metabolite prediction software packages (Meteor, MetaSite, and StarDrop) through independent and synergistic use
Huybrecht T'jollyn
Koen Boussery
RJ Mortishire-Smith
K Coe
B De Boeck
Jan Van Bocxlaer
G Mannens
A1
Journal Article
in
DRUG METABOLISM AND DISPOSITION
2011
Human salivary cortisol, part I : development and full validation of an LC-MS/MS based method
Mieke Carlier
Kathleen Deiteren
Jan Van Bocxlaer
Kathleen Croes
C3
Conference
2011
In vitro cytochrome P450 activity: development and validation of a sensitive high performance liquid chromatography–tandem mass spectrometry method for the quantification of six probe metabolites after derivatization with pyridine-3-sulfonyl chloride in an aqueous environment
Lies De Bock
Sofie Vande Casteele
SYLVIE MULLIEZ
Koen Boussery
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY A
2011
Pharmacokinetics of two formulations of omeprazole administered through a gastrostomy tube in patients with severe neurodevelopmental problems
Koen Boussery
Julie De Smet
Pieter De Cock
Saskia Vande Velde
Els Mehuys
Peter De Paepe
Jean Paul Remon
Jan Van Bocxlaer
Myriam Van Winckel
A1
Journal Article
in
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
2011
2010
A bio-analytical hydrophilic interaction LC-MS/MS method for the simultaneous quantification of omeprazole and lansoprazole in human plasma in support of a pharmacokinetic omeprazole study in children
Julie De Smet
Koen Boussery
Pieter De Cock
Peter De Paepe
Jean Paul Remon
Myriam Van Winckel
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF SEPARATION SCIENCE
2010
A comprehensive LC-MS-based quantitative analysis of fentanyl-like drugs in plasma and urine
Sarah Cooreman
Christa Deprez
Frank Martens
Jan Van Bocxlaer
Kathleen Croes
A1
Journal Article
in
JOURNAL OF SEPARATION SCIENCE
2010
A new discriminative criterion for the development of Franz diffusion tests for transdermal pharmaceuticals
Bram Baert
Jente Boonen
Christian Burvenich
Nathalie Roche
Filip Stillaert
Phillip Blondeel
Jan Van Bocxlaer
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
2010
Analysis of omnoponum by surface-ionization mass spectrometry and liquid chromatography tandem mass spectrometry methods
Dilshadbek Usmanov
Usman Khasanov
Aleksey Pantsirev
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2010
Analytical characterization and comparison of the blood-brain barrier permeability of eight opioid peptides
Sylvia Van Dorpe
Antita Adriaens
Ingeborgh Polis
Kathelijne Peremans
Jan Van Bocxlaer
Bart De Spiegeleer
A1
Journal Article
in
PEPTIDES
2010
Mechanism of light-induced oxidation of nitrosylmyoglobin
Merete B Munk
Kevin Huvaere
Jan Van Bocxlaer
Leif H Skibsted
A1
Journal Article
in
FOOD CHEMISTRY
2010
2009
Improved analyte detectability of proteins and peptide lysates by means of multiple large-volume injection in LC-MS
Michael Storme
Ruben T'Kindt
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF SEPARATION SCIENCE
2009
JEM Spotlight: Fungi, mycotoxins and microbial volatile organic compounds in mouldy interiors from water-damaged buildings
Viviana Polizzi
Barbara Delmulle
An Adams
A Moretti
A Susca
AM Picco
Yves Rosseel
Ruben T'Kindt
Jan Van Bocxlaer
Norbert De Kimpe
Carlos Van Peteghem
Sarah De Saeger
A1
Journal Article
in
JOURNAL OF ENVIRONMENTAL MONITORING
2009
Joint GC-MS and LC-MS platforms for comprehensive plant metabolomics: Repeatability and sample pre-treatment
Ruben T'Kindt
Kris Morreel
Dieter Deforce
Wout Boerjan
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
2009
Pharmacokinetics of fluoroquinolones in critical care patients: A bio-analytical HPLC method for simultaneous quantification of ofloxacin, ciprofloxacin and moxifloxacin in human plasma
Julie De Smet
Koen Boussery
Kirsten Colpaert
Peter De Sutter
Peter De Paepe
Johan Decruyenaere
Jan Van Bocxlaer
A1
Journal Article
in
Journal of Chromatography B
2009
2008
Analysis of oligonucleotides using capillary zone electrophoresis and electrospray mass spectrometry
An Willems
Dieter Deforce
Jan Van Bocxlaer
Bookchapter
in
Capillary electrophoresis
2008
Evaluation of hydrophilic interaction chromatography versus reversed-phase chromatography in a plant metabolomics perspective
Ruben T'Kindt
Michael Storme
Dieter Deforce
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF SEPARATION SCIENCE
2008
LC-MS metabolic profiling of Arabidopsis thaliana plant leaves and cell cultures: optimization of pre-LC-MS procedure parameters
Ruben T'Kindt
Lieven De Veylder
Michael Storme
Dieter Deforce
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
2008
Monitoring the benzene contents in soft drinks using headspace gas chromatography-mass spectrometry: A survey of the situation on the Belgian market
Christof Van Poucke
Christel Detavernier
Jan Van Bocxlaer
Rudi Vermeylen
Carlos Van Peteghem
A1
Journal Article
in
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
2008
Quantitative determination of glycopyrrolate in human plasma by liquid chromatography-electrospray ionization mass spectrometry: The use of a volatile ion-pairing agent during both liquid-liquid extraction and liquid chromatography
ML Storme
Ruben T'Kindt
Wim Goeteyn
KOEN REYNTJENS
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
2008
2007
Broad-spectrum separations in metabolomics using enhanced polar LC stationary phases: A dedicated evaluation using plant metabolites
Ruben T'Kindt
G ALAERTS
Y VANDER HEYDEN
Dieter Deforce
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF SEPARATION SCIENCE
2007
Comparison of two compartmental pharmacokinetics models to predict the time course of propofol plasma concentration during the first 5 minutes after a bolus injection
Hilde Van Kerckhoven
Eric Mortier
Jan Van Bocxlaer
Michel Struys
A2
Journal Article
in
ACTA ANAESTHESIOLOGICA BELGICA
2007
Influence of administration rate on propofol plasma - Effect site equilibration
Michel Struys
Marc Coppens
N DE NEVE
Eric Mortier
AG DOUFAS
Jan Van Bocxlaer
SL SHAFER
A1
Journal Article
in
ANESTHESIOLOGY
2007
Postmortem distribution of 3,4-methylenedioxy-N,N-dimethyl-amphetamine (MDDM or MDDA) in a fatal MDMA overdose
Els De Letter
Willy Lambert
MPLA BOUCHE
JACM CORDONNIER
Jan Van Bocxlaer
Michel Piette
A1
Journal Article
in
INTERNATIONAL JOURNAL OF LEGAL MEDICINE
2007
The occurrence of benzene in soft drinks : a survey of the situation on the Belgian market.
Christof Van Poucke
Christel Detavernier
Jan Van Bocxlaer
Reinhilde Vermeylen
Carlos Van Peteghem
C3
Conference
2007
2006
Class identity assignment for amphetamines using neural networks and GC-FTIR data
S Gosav
Mirela Praisler
Jan Van Bocxlaer
Andreas De Leenheer
Desiré L Massart
A1
Journal Article
in
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
2006
Flavin-induced photodecomposition of sulfur-containing amino acids is decisive in the formation of beer lightstruck flavor
Kevin Huvaere
ML ANDERSEN
Michael Storme
Jan Van Bocxlaer
LH SKIBSTED
Denis De Keukeleire
A1
Journal Article
in
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
2006
Quantitation of artemisinin and its biosynthetic precursors in Artemisia annua L. by high performance liquid chromatography - electrospray quadrupole time-of-flight tandem mass spectrometry
Filip Van Nieuwerburgh
Sofie Vande Casteele
Lies Maes
Alain Goossens
Dirk Inzé
Jan Van Bocxlaer
Dieter Deforce
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY A
2006
Simultaneous quantitative analysis of the antimalarials pyrimethamine and sulfamethoxypyrazine in plasma samples using liquid chromatography/tandem mass spectrometry
Michael Storme
FH JANSEN
W GOETEYN
Jan Van Bocxlaer
A1
Journal Article
in
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
2006
2005
Analysis of nucleic acid constituents by on-line capillary electrophoresis-mass spectrometry
An Willems
Dieter Deforce
Carlos Van Peteghem
Jan Van Bocxlaer
A1
Journal Article
in
ELECTROPHORESIS
2005
Capillary liquid chromatography and tandem mass spectrometry for the quantification of enkephalins in cerebrospinal fluid
Bart Sinnaeve
Michael Storme
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF SEPARATION SCIENCE
2005
Confirmation of the identity of residues using quadrupole time-of-flight mass spectrometry
Jan Van Bocxlaer
Sofie Vande Casteele
Christof Van Poucke
Carlos Van Peteghem
A1
Journal Article
in
ANALYTICA CHIMICA ACTA
2005
Development of a quality control method for the characterization of oligonucleotides by capillary zone electrophoresis-electrospray ionization-quadrupole time of flight-mass spectrometry
An Willems
Dieter Deforce
Carlos Van Peteghem
Jan Van Bocxlaer
A1
Journal Article
in
ELECTROPHORESIS
2005
Differential proteome analysis of Chronic lymphocytic leukemia subtypes
Ben Geeraerts
Aline Dhondt
Dirk Elewaut
Jan Van Bocxlaer
Dieter Deforce
C3
Conference
2005
Exploring and modelling the responses of electrospray and atmospheric pressure chemical ionization techniques based on molecular descriptors
S CAETANO
T DECAESTECKER
R PUT
M DASZYKOWSKI
Jan Van Bocxlaer
Y VANDER HEYDEN
A1
Journal Article
in
ANALYTICA CHIMICA ACTA
2005
LC-MS/MS in the elucidation of an isomer of the recreational drug methylenedioxy ethylamphetamine: Methylenedioxy dimethylamphetamine
Sofie Vande Casteele
MPL BOUCHE
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF SEPARATION SCIENCE
2005
Liquid chromatographic-mass spectrometric assay for simultaneous pyrimethamine and sulfadoxine determination in human plasma samples
Bart Sinnaeve
Tineke Decaestecker
PG RISHA
Jean Paul Remon
Chris Vervaet
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY A
2005
Recent trends in analytical procedures in forensic toxicology
Jan Van Bocxlaer
A1
Journal Article
in
THERAPEUTIC DRUG MONITORING
2005
The use of tryptic marker-peptides for the quantitative analysis of Cystatin C
Michael Storme
Bart Sinnaeve
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF SEPARATION SCIENCE
2005
2004
Evaluation of Nano-LC-MS/MS in a column switching setup as a tool for the absolute quantification of peptides in the picomolar range
Bart Sinnaeve
Karine Clauwaert
Jan Van Bocxlaer
C1
Conference
2004
Evaluation of nano-liquid chromatography-tandem mass spectrometry in a column switching setup for the absolute quantification of peptides in the picomolar range
Bart Sinnaeve
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY A
2004
Information-dependent acquisition-mediated LC-MS/MS screening procedure with semiquantitative potential
TN DECAESTECKER
Sofie Vande Casteele
PE WALLEMACQ
Carlos Van Peteghem
DL DEFORE
Jan Van Bocxlaer
A1
Journal Article
in
ANALYTICAL CHEMISTRY
2004
Interpretation of a 3,4-methylenedioxymethamphetamine (MDMA) blood level: discussion by means of a distribution study in two fatalities
Els De Letter
MPLA BOUCHE
Jan Van Bocxlaer
Willy Lambert
Michel Piette
A1
Journal Article
in
FORENSIC SCIENCE INTERNATIONAL
2004
Optimization of solid-phase extraction for a liquid chromatographic-tandem mass spectrometric general unknown screening procedure by means of computational techniques
Tineke Decaestecker
Willy Lambert
Carlos Van Peteghem
Dieter Deforce
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY A
2004
Photooxidative degradation of beer bittering principles: product analysis with respect to lightstruck flavour formation
Kevin Huvaere
Bart Sinnaeve
Jan Van Bocxlaer
Denis De Keukeleire
A1
Journal Article
in
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
2004
Production of compound A and carbon monoxide in circle systems : an in vitro comparison of two carbon dioxide absorbents
Michel Struys
MPLA Bouche
Georges Rolly
YDI Vandevivere
Dorine Dyzers
Wim Goeteyn
Linda Versichelen
Jan Van Bocxlaer
Eric Mortier
A1
Journal Article
in
ANAESTHESIA
2004
Rapid characterization of oligonucleotides by capillary liquid chromatography-nano electrospray quadrupole time-of-flight mass spectrometry
An Willems
Dieter Deforce
Willy Lambert
Carlos Van Peteghem
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY A
2004
The determination of cocaine, benzoylecgonine, and cocaethylene in small-volume oral fluid samples by liquid chromatography-quadrupole-time-of-flight mass spectrometry
K CLAUWAERT
T DECALESTECKER
Kjell Mortier
Willy Lambert
Dieter Deforce
Carlos Van Peteghem
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
2004
2003
Confirmation of ofloxacin precipitation in corneal deposits by microbore liquid chromatography - quadrupole time-of-flight tandem mass spectrometry
Bart Sinnaeve
Tineke Decaestecker
Ilse Claerhout
Philippe Kestelyn
Jean Paul Remon
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
2003
Corneal deposits after the topical use of ofloxacin in two children with vernal keratoconjunctivitis
Ilse Claerhout
Philippe Kestelyn
Françoise Meire
Jean Paul Remon
Tineke Decaestecker
Jan Van Bocxlaer
A1
Journal Article
in
BRITISH JOURNAL OF OPHTHALMOLOGY
2003
Exact mass measurement of product ions for the structural confirmation and identification of unknown compounds using a quadrupole time-of-flight spectrometer: a simplified approach using combined tandem mass spectrometric functions
Karine Clauwaert
Sofie Vande Casteele
Bart Sinnaeve
Dieter Deforce
Willy Lambert
Carlos Van Peteghem
Jan Van Bocxlaer
A1
Journal Article
in
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
2003
Immunohistochemical demonstration of the amphetamine derivatives 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) in human post-mortem tissues
Els De Letter
Marc Espeel
Marijke Craeymeersch
Willy Lambert
Jan Van Bocxlaer
Michel Piette
C1
Conference
2003
Presence of N,N-Dimethyl-3,4-Methylenedioxyamphetamine(MDDM) in a fatal MDMA-overdose
M BOUCHE
Els De Letter
Sofie Vande Casteele
Philippe Van Rompaey
Michel Piette
Jan Van Bocxlaer
C1
Conference
2003
Suitability testing of commercial solid-phase extraction sorbents for sample clean-up in systematic toxicological analysis using liquid chromatography-(tandem) mass spectrometry
Tineke Decaestecker
EM COOPMAN
Carlos Van Peteghem
Jan Van Bocxlaer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
2003
The protein expression pattern of CLL cells is stable over six months intervals
Ben Geeraerts
Jan Van Bocxlaer
Willy Lambert
Carlos Van Peteghem
Dieter Deforce
Dirk Elewaut
C3
Conference
2003
2002
Analysis of benzo(a)pyrene diol epoxide-DNA adducts by capillary zone electrophoresis-electrospray ionization-mass spectrometry in conjunction with sample stacking.
An Willems
Dieter Deforce
Elfrida Van Den Eeckhout
Willy Lambert
Carlos Van Peteghem
Andreas De Leenheer
Jan Van Bocxlaer
A1
Journal Article
in
ELECTROPHORESIS
2002
Automated recognition of ergogenic aids using Soft Independent Modeling of Class Analogy (SIMCA).
M PRAISLER
Jan Van Bocxlaer
Andreas De Leenheer
DL MASSART
A1
Journal Article
in
TURKISH JOURNAL OF CHEMISTRY
2002
Chemometric detection of thermally degraded samples in the analysis of drugs of abuse with gas chromatography-Fourier-transform infrared spectroscopy.
M PRAISLER
Jan Van Bocxlaer
Andreas De Leenheer
DL MASSART
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY A
2002
Distribution profile study of 4-MTA based on a fatal intoxication.
Tineke Decaestecker
E DE LETTER
Karine Clauwaert
Marie-Paule Bouche
Willy Lambert
Jan Van Bocxlaer
M PIETTE
E VAN DEN EECKHOUT
Carlos Van Peteghem
Andreas De Leenheer
C1
Conference
2002
Distribution study of 3,4-methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine in a fatal overdose
Els De Letter
Karine Clauwaert
Willy Lambert
Jan Van Bocxlaer
Andreas De Leenheer
Michel Piette
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
2002
No Compound A formation with Superia (R) during minimal-flow sevoflurane anesthesia: A comparison with Sofnolime.
Marie-Paule Bouche
Linda Versichelen
Michel Struys
Jan Van Bocxlaer
Andreas De Leenheer
Eric Mortier
Georges Rolly
A1
Journal Article
in
ANESTHESIA AND ANALGESIA
2002
Post-mortem redistribution of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") in the rabbit Part I - experimental approach after in vivo intravenous infusion.
Els De Letter
Karine Clauwaert
Frans Belpaire
Willy Lambert
Jan Van Bocxlaer
Michel Piette
A1
Journal Article
in
INTERNATIONAL JOURNAL OF LEGAL MEDICINE
2002
Post-mortem redistribution of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") in the rabbit Part II: post-mortem infusion in trachea or stomach.
Els De Letter
Frans Belpaire
Karine Clauwaert
Willy Lambert
Jan Van Bocxlaer
Michel Piette
A1
Journal Article
in
INTERNATIONAL JOURNAL OF LEGAL MEDICINE
2002
Quantitative determination of n-propane, iso-butane, and n-butane by headspace GC-MS in intoxications by inhalation of lighter fluid.
Marie-Paule Bouche
Willy Lambert
Jan Van Bocxlaer
Michel Piette
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
2002
Simultaneous, quantitative determination of opiates, amphetamines, cocaine and benzoylecgonine in oral fluid by liquid chromatography quadrupole-time-of-flight mass spectrometry.
Kjell Mortier
Kristof Maudens
Willy Lambert
Karine Clauwaert
Jan Van Bocxlaer
Dieter Deforce
Carlos Van Peteghem
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
2002
2001
A fatal case of moclobemide-citalopram intoxication - Reply.
Riet Dams
Tom Benijts
Willy Lambert
Jan Van Bocxlaer
Carlos Van Peteghem
Andreas De Leenheer
D VAN VARENBERGH
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
2001
A fatal case of serotonin syndrome after combined moclobemide-citalopram intoxication
Riet Dams
Tom Benijts
Willy Lambert
Jan Van Bocxlaer
D VAN VARENBERGH
Andreas De Leenheer
C1
Conference
2001
A fatal case of serotonin syndrome after combined moclobemide-citalopram intoxication.
Riet Dams
Tom Benijts
Willy Lambert
Jan Van Bocxlaer
D VAN VARENBERGH
CV PETEGHEM
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
2001
A structured approach for screening the relevant factors in a PTV injection optimizing procedure
Marie-Paule Bouche
M PRAISLER
Jan Van Bocxlaer
Andreas De Leenheer
C1
Conference
2001
Compound A production from sevoflurane is not less when KOH-free absorbent is used in a closed-circuit lung model system.
Linda Versichelen
Marie-Paule Bouche
Michel Struys
Jan Van Bocxlaer
Eric Mortier
Andreas De Leenheer
Georges Rolly
A1
Journal Article
in
BRITISH JOURNAL OF ANAESTHESIA
2001
Computer-aided screening for hallucinogenic and stimulant amphetamines with gas chromatography-Fourier transform infrared spectroscopy (GC-FTIR).
M PRAISLER
Inge Dirinck
Jan Van Bocxlaer
Andreas De Leenheer
DL MASSART
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
2001
Evaluation of automated MS to MS/MS function switching for comprehensive drug profiling analysis using a quadrupole time-of-flight mass spectrometer
Tineke Decaestecker
Karine Clauwaert
Jan Van Bocxlaer
Willy Lambert
E VAN DEN EECKHOUT
C VAN PETEGHEM
Bookchapter
in
Advances in Mass Spectrometry. E. Gelpi, Editor, John Wiley & Sons Ltd. Chichester, 2001, vol. 15, 2 pp
2001
Fatal 4-MTA intoxication: Development of a liquid chromatographic-tandem mass spectrometric assay for multiple matrices.
Tineke Decaestecker
Els De Letter
Karine Clauwaert
Marie-Paule Bouche
Willy Lambert
Jan Van Bocxlaer
Michel Piette
Elfrida Van Den Eeckhout
Carlos Van Peteghem
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
2001
Multivariate determination of the length of the side chain of illicit amphetamine analogues with GC-FTIR spectra.
M PRAISLER
Jan Van Bocxlaer
Andreas De Leenheer
DL MASSART
A2
Journal Article
in
The Annals of the University 'Dunãrea de Jos', Fascicle II, XVIII, 2000
2001
Only carbon dioxide absorbents free of both NaOH and KOH do not generate compound A during in vitro closed-system sevoflurane: evaluation of five absorbents
Linda Versichelen
Marie-Paule Bouche
Georges Rolly
Jan Van Bocxlaer
Michel Struys
Andreas De Leenheer
Eric Mortier
A1
Journal Article
in
ANESTHESIOLOGY
2001
Pitfalls associated with liquid chromatography/electrospray tandem mass spectrometry in quantitative bioanalysis of drugs of abuse in saliva.
Kjell Mortier
Karine Clauwaert
Willy Lambert
Jan Van Bocxlaer
Elfrida Van Den Eeckhout
Carlos Van Peteghem
Andreas De Leenheer
A1
Journal Article
in
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
2001
Quantitation of amphetamine, methamphetamine, MDA, MDMA and MDEA in saliva with a Q-TOF LC/MS/MS system
Karine Clauwaert
Jan Van Bocxlaer
An Willems
Kjell Mortier
Willy Lambert
E VAN DEN EECKHOUT
C1
Conference
2001
Quantitation of cocaine, benzoylecgonine and cocaethylene in saliva with a LC/MS/MS using small sample volumes
Karine Clauwaert
Jan Van Bocxlaer
Tineke Decaestecker
Kjell Mortier
Willy Lambert
E VAN DEN EECKHOUT
Carlos Van Peteghem
C1
Conference
2001
Quantitative GC-MS of volatiles: Compound A determination in the vapor phase of sevoflurane based anesthesia systems
Marie-Paule Bouche
Jan Van Bocxlaer
G ROLLY
L VERSICHELEN
M STRUYS
E MORTIER
Willy Lambert
Andreas De Leenheer
Bookchapter
in
Advances in Mass Spectrometry. E. Gelpi, Editor, John Wiley & Sons Ltd. Chichester, 2001, vol. 15, 2 pp
2001
Quantitative determination of n-propane, isobutane and n-nutane by headspace GC-MS in a fatal intoxication by inhalation of lighter fluid
Marie-Paule Bouche
Willy Lambert
Jan Van Bocxlaer
M PIETTE
Andreas De Leenheer
C1
Conference
2001
Quantitative determination of vapor-phase compound A in sevoflurane anesthesia using gas chromatography-mass spectrometry.
Marie-Paule Bouche
Jan Van Bocxlaer
Georges Rolly
Linda Versichelen
Michel Struys
Eric Mortier
Andreas De Leenheer
A1
Journal Article
in
CLINICAL CHEMISTRY
2001
Stability study of the designer drugs "MDA, MDMA and MDEX" in water, serum, whole blood, and urine under various storage temperatures.
Karine Clauwaert
Jan Van Bocxlaer
Andreas De Leenheer
A1
Journal Article
in
FORENSIC SCIENCE INTERNATIONAL
2001
2000
Comparison between automated knowledge-based systems identifying and classifying amphetamine analogues using vapor-phase FTIR-spectra and mass spectra.
Inge Dirinck
M PRAISLER
Jan Van Bocxlaer
Andreas De Leenheer
DL MASSART
A2
Journal Article
in
The 37th triennial Meeting of The International Association of Forensic Toxicologists / Lech T, Wójcikiewicz J., Eds. - Krakow : Institute of Forensic Research Publishers, 2000 - 5 pp.
2000
Comparison of an enzymatic alcohol dehydrogenase assay and alcohol headspace GC-FID method using statistical analysis on real forensic blood and urine samples.
Katrien Arys
Jan Van Bocxlaer
Willy Lambert
Carlos Van Peteghem
Andreas De Leenheer
A2
Journal Article
in
The 37th triennial Meeting of The International Association of Forensic Toxicologists / Lech T, Wójcikiewicz J., Eds. - Krakow : Institute of Forensic Research Publishers, 2000 - 4 pp.
2000
Determination of the designer drugs 3,4-methylenedioxymethamphetamine, 3,4-methylenedioxyethylamphetamine, and 3,4-methylenedioxyamphetamine with HPLC and fluorescence detection in whole blood, serum, vitreous humor, and urine.
Karine Clauwaert
Jan Van Bocxlaer
Els De Letter
Serge Van Calenbergh
Willy Lambert
Andreas De Leenheer
A1
Journal Article
in
CLINICAL CHEMISTRY
2000
Evaluation of automated single mass spectrometry to tandem mass spectrometry function switching for comprehensive drug profiling analysis using a quadrupole time-of-flight mass spectrometer.
Tineke Decaestecker
Karine Clauwaert
Jan Van Bocxlaer
Willy Lambert
Elfrida Van Den Eeckhout
Carlos Van Peteghem
Andreas De Leenheer
A1
Journal Article
in
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
2000
Exploratory analysis for the automated identification of amphetamines from vapour-phase FTIR spectra.
M PRAISLER
Inge Dirinck
Jan Van Bocxlaer
Andreas De Leenheer
DL MASSART
A1
Journal Article
in
ANALYTICA CHIMICA ACTA
2000
Identification of novel illicit amphetamines from vapor-phase FTIR spectra - a chemometrical solution.
M PRAISLER
Inge Dirinck
Jan Van Bocxlaer
Andreas De Leenheer
DL MASSART
A1
Journal Article
in
TALANTA
2000
In vitro compound a formation in a computer-controlled closed-circuit anesthetic apparatus - Comparison with a classical valve circuit.
Linda Versichelen
Georges Rolly
Marie-Paule Bouche
Jan Van Bocxlaer
Michel Struys
C VAN DER HERTEN
Andreas De Leenheer
Eric Mortier
A1
Journal Article
in
ANESTHESIOLOGY
2000
Is vitreous humour useful for the interpretation of 3,4-methylenedioxymethamphetamine (MDMA) blood levels? Experimental approach with rabbits
Els De Letter
Peter De Paepe
Karine Clauwaert
Frans Belpaire
Willy Lambert
Jan Van Bocxlaer
Michel Piette
A1
Journal Article
in
INTERNATIONAL JOURNAL OF LEGAL MEDICINE
2000
Liquid chromatography-mass spectrometry in forensic toxicology
Jan Van Bocxlaer
KM Clauwaert
Willy Lambert
Dieter Deforce
Elfrida Van Den Eeckhout
Andreas De Leenheer
A1
Journal Article
in
MASS SPECTROMETRY REVIEWS
2000
Modern Chromatographic Analysis of Vitamins (Third Edition, Revised and Expanded)
Andreas De Leenheer
Willy Lambert
Jan Van Bocxlaer
Bookchapter
in
Chromatographic Science Series, 84. Marcel Dekker Inc. New York and Basel, 2000, 616 p
2000
Pattern recognition techniques screening for drugs of abuse with gas chromatography-Fourier transform infrared spectroscopy.
M PRAISLER
Inge Dirinck
Jan Van Bocxlaer
Andreas De Leenheer
DL MASSART
A1
Journal Article
in
TALANTA
2000
Quantitative determination of paraquat by HPLC-DAD following chemical reduction with sodium borohydride in a fatal intoxication
Katrien Arys
Jan Van Bocxlaer
Karine Clauwaert
Willy Lambert
Michel Piette
Carlos Van Peteghem
Andreas De Leenheer
C1
Conference
2000
Quantitative determination of paraquat in a fatal intoxication by HPLC-DAD following chemical reduction with sodium borohydride.
Katrien Arys
Jan Van Bocxlaer
Karine Clauwaert
Willy Lambert
Michel Piette
Carlos Van Peteghem
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
2000
Segmental analysis for cocaine and metabolites by HPLC in hair of suspected drug overdose cases.
Karine Clauwaert
Jan Van Bocxlaer
Willy Lambert
Andreas De Leenheer
A1
Journal Article
in
FORENSIC SCIENCE INTERNATIONAL
2000
Toxicological analysis: liquid chromatography
Andreas De Leenheer
Willy Lambert
Jan Van Bocxlaer
Bookchapter
in
Encyclopedia of Separation Science; Ed. I.D. Wilson. Academic Press, San Diego, San Francisco, New York, 2000, 7 pp
2000
1999
Investigation of the quantitative properties of the quadrupole orthogonal acceleration time-of-flight mass spectrometer with electrospray ionisation using 3,4-methylenedioxymethamphetamine.
Karine Clauwaert
Jan Van Bocxlaer
HJ MAJOR
JA CLAEREBOUDT
Willy Lambert
Elfrida Van Den Eeckhout
Carlos Van Peteghem
Andreas De Leenheer
A1
Journal Article
in
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
1999
1998
Application of gas chromatography Fourier transform infrared spectrometry to the analysis of amphetamine analogues.
Inge Dirinck
Evelyne Meyer
Jan Van Bocxlaer
Willy Lambert
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY A
1998
Narrow-bore HPLC in combination with fluorescence and electrospray mass spectrometric detection for the analysis of cocaine and metabolites in human hair.
KM CLAUWAERT
Jan Van Bocxlaer
Willy Lambert
Elfrida Van Den Eeckhout
F LEMIERE
EL ESMANS
Andreas De Leenheer
A1
Journal Article
in
ANALYTICAL CHEMISTRY
1998
1997
Liquid chromatographic determination of cocaine, benzoylecgonine, and cocaethylene in whole blood and serum samples with diode-array detection.
KM CLAUWAERT
Jan Van Bocxlaer
Willy Lambert
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHIC SCIENCE
1997
Potential of high-performance liquid chromatography with photodiode array detection in forensic toxicology.
Willy Lambert
Jan Van Bocxlaer
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY B
1997
Quantitative colorimetric determination of urinary p-aminophenol with an automated analyzer.
Jan Van Bocxlaer
KM CLAUWAERT
Willy Lambert
Andreas De Leenheer
A1
Journal Article
in
CLINICAL CHEMISTRY
1997
Quantitative determination of amphetamine and alpha-phenylethylamine enantiomers in judicial samples using capillary gas chromatography.
Jan Van Bocxlaer
Willy Lambert
Linda Thienpont
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
1997
Relevance of toxicological screening for chloroquine in nonmalarious areas
Willy Lambert
Evelyne Meyer
Jan Van Bocxlaer
Andreas De Leenheer
Michel Piette
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
1997
Tissue distribution of amphetamine isomers in a fatal overdose.
Evelyne Meyer
Jan Van Bocxlaer
IM DIRINCK
Willy Lambert
Linda Thienpont
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
1997
1996
Analysis of Zopiclone (Imovane(R)) in postmortem specimens by GC-MS and HPLC with diode-array detection.
Jan Van Bocxlaer
Evelyne Meyer
Karine Clauwaert
Willy Lambert
Michel Piette
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
1996
Analysis of cocaine, benzoylecgonine, and cocaethylene in urine by HPLC with diode array detection.
Karine Clauwaert
Jan Van Bocxlaer
Willy Lambert
Andreas De Leenheer
A1
Journal Article
in
ANALYTICAL CHEMISTRY
1996
Identification of a-Phenylethylamine in Judicial Samples
Evelyne Meyer
Jan Van Bocxlaer
Willy Lambert
Linda Thienpont
Andreas De Leenheer
A2
Journal Article
in
Journal Anal. Toxicol., 20, pp. 116-120, 4 figg., 1 tab
1996
Identification of alpha-phenylethylamine in judicial samples.
Evelyne Meyer
Jan Van Bocxlaer
Willy Lambert
Linda Thienpont
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
1996
Quantitative gas chromatographic analysis of 3-cyano-3,3-diphenylpropionic acid, the acidic metabolite of bezitramide (Burgodin((R))), in urine.
SM DEBAERE
Willy Lambert
Jan Van Bocxlaer
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
1996
Trazodone and dothiepin poisoning - Reply.
Willy Lambert
Jan Van Bocxlaer
Michel Piette
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
1996
Zopiclone poisoning - Reply.
Jan Van Bocxlaer
Evelyne Meyer
Karine Clauwaert
Willy Lambert
Michel Piette
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
1996
1995
CHARACTERIZATION OF ACYLCARNITINES USING FAST-ATOM-BOMBARDMENT MASS-SPECTROMETRY AND GAS-CHROMATOGRAPHY MASS-SPECTROMETRY.
Jan Van Bocxlaer
M CLAEYS
H VANDENHEUVEL
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF MASS SPECTROMETRY
1995
Determination of Chloral Hydrate and Metabolites in a Fatal Intoxication.
Evelyne Meyer
Jan Van Bocxlaer
Willy Lambert
Michel Piette
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
1995
α-Phenylethylamine identified in judicial samples
Evelyne Meyer
Jan Van Bocxlaer
Willy Lambert
Linda Thienpont
Andreas De Leenheer
A1
Journal Article
in
FORENSIC SCIENCE INTERNATIONAL
1995
1994
A FATAL CASE OF TRAZODONE AND DOTHIEPIN POISONING - TOXICOLOGICAL FINDINGS.
Willy Lambert
Jan Van Bocxlaer
Michel Piette
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF ANALYTICAL TOXICOLOGY
1994
Determination of Embutramide in Biological Matrices by Gas Chromatography with Nitrogen-phosphorus Detection.
JZ HUO
Jan Van Bocxlaer
Willy Lambert
Andreas De Leenheer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS
1994
1993
SOLID-PHASE EXTRACTION TECHNIQUE FOR GAS-CHROMATOGRAPHIC PROFILING OF ACYLCARNITINES.
Jan Van Bocxlaer
Andreas De Leenheer
A1
Journal Article
in
CLINICAL CHEMISTRY
1993
1992
Gas chromatographic/mass spectrometric identification of 3-hydroxydicarboxylic acids in urine
BJ Verhaeghe
Jan Van Bocxlaer
Andreas De Leenheer
A1
Journal Article
in
BIOLOGICAL MASS SPECTROMETRY
1992
Meprobamate Intoxication: Rare and Difficult to Find.
Willy Lambert
Andreas De Leenheer
Jan Van Bocxlaer
Michel Piette
A1
Journal Article
in
Journal of toxicology. Clinical toxicology
1992
