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Researcher
Jan Spaas
Profile
Projects
Publications
Activities
Awards & Distinctions
42
Results
2024
Safety assessment of equine allogeneic tenogenic primed mesenchymal stem cells in horses with naturally occurring tendon and ligament injuries
Stephanie Carlier
Eva Depuydt
Lore Van Hecke
Ann Martens
Jimmy Saunders
Jan Spaas
A1
Journal Article
in
FRONTIERS IN VETERINARY SCIENCE
2024
2023
Immunogenicity analysis of BPV-1 positive equine sarcoid-derived cultured fibroblasts
Lien Gysens
Eva Depuydt
Marco Patruno
Maarten Haspeslagh
Jan Spaas
Ann Martens
A1
Journal Article
in
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
2023
Immunogenicity analysis of BPV-1 positive equine sarcoid-derived cultured fibroblasts
Lien Gysens
Eva Depuydt
Marco Patruno
Maarten Haspeslagh
Jan Spaas
Ann Martens
C3
Conference
2023
Low-dose xenogeneic mesenchymal stem cells target canine osteoarthritis through systemic immunomodulation and homing
Charlotte Beerts
Sarah Broeckx
Eva Depuydt
Liesa Tack
Lore Van Hecke
Koen Chiers
Leen Van Brantegem
Gabriele Braun
Klaus Hellmann
Nathalie de Bouvré
et al.
A1
Journal Article
in
ARTHRITIS RESEARCH & THERAPY
2023
2022
Assessing the functional properties of tenogenic primed mesenchymal stem cells in ex vivo equine tendon and ligament explants : a preliminary study
Eva Depuydt
Koen Chiers
Lore Van Hecke
Jimmy Saunders
Ann Martens
Frederik Pille
Jan Spaas
A1
Journal Article
in
STEM CELL RESEARCH
2022
Cellular and humoral immunogenicity investigation of single and repeated allogeneic tenogenic primed mesenchymal stem cell treatments in horses suffering from tendon injuries
Eva Depuydt
Sarah Y. Broeckx
Koen Chiers
Marco Patruno
Laura Da Dalt
Luc Duchateau
Jimmy Saunders
Frederik Pille
Ann Martens
Lore Van Hecke
et al.
A1
Journal Article
in
FRONTIERS IN VETERINARY SCIENCE
2022
Editorial : one health and veterinary regenerative medicine : translational applications
Tracy L. Webb
Jan Spaas
Debbie J. Guest
Editorial material
2022
The potential of equine tenogenic primed mesenchymal stem cells for horses with tendon injuries
Eva Depuydt
Ann Martens
Koen Chiers
Frederik Pille
Jan Spaas
Dissertation
2022
Xenogeneic use of equine peripheral blood-derived mesenchymal stem cells for treatment of osteoarthritis in dogs
Charlotte Beerts
Jimmy Saunders
Jan Spaas
Kathelijne Peremans
Dissertation
2022
2021
Repeated intra-articular administration of equine allogeneic peripheral blood-derived mesenchymal stem cells does not induce a cellular and humoral immune response in horses
Lore Van Hecke
Carmelo Magri
Luc Duchateau
Charlotte Beerts
Florian Geburek
Marc Suls
Laura Da Dalt
Marco Patruno
Jimmy Saunders
Sarah Y. Broeckx
et al.
A1
Journal Article
in
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
2021
Review : mesenchymal stem cell therapy in canine osteoarthritis research : 'Experientia Docet' (experience will teach us)
Carlien Brondeel
Glenn Pauwelyn
Evelien de Bakker
Jimmy Saunders
Yves Samoy
Jan Spaas
A1
Journal Article
in
FRONTIERS IN VETERINARY SCIENCE
2021
Scintigraphic tracking of 99mTechnetium-labelled equine peripheral blood-derived mesenchymal stem cells after intravenous, intramuscular, and subcutaneous injection in healthy dogs
Charlotte Beerts
Carlien Brondeel
Glenn Pauwelyn
Eva Depuydt
Liesa Tack
Luc Duchateau
Yangfeng Xu
Jimmy Saunders
Kathelijne Peremans
Jan Spaas
A1
Journal Article
in
STEM CELL RESEARCH & THERAPY
2021
The evaluation of equine allogeneic tenogenic primed mesenchymal stem cells in a surgically induced superficial digital flexor tendon lesion model
Eva Depuydt
Sarah Y. Broeckx
Lore Van Hecke
Koen Chiers
Leen Van Brantegem
Hans van Schie
Charlotte Beerts
Jan Spaas
Frederik Pille
Ann Martens
A1
Journal Article
in
FRONTIERS IN VETERINARY SCIENCE
2021
2020
Safety and immunomodulatory properties of equine peripheral blood-derived mesenchymal stem cells in healthy cats
Yves Debosschere
Eva Depuydt
Glenn Pauwelyn
Charlotte Beerts
Lore Van Hecke
Leen Verhaert
Luc Duchateau
Jimmy Saunders
Liesa Tack
Jan Spaas
A1
Journal Article
in
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
2020
2019
A feasibility study on the use of equine chondrogenic induced mesenchymal stem cells as a treatment for natural occurring osteoarthritis in dogs
Robert Daems
Lore Van Hecke
Ilona Schwarzkopf
Eva Depuydt
Sarah Y. Broeckx
Michael David
Charlotte Beerts
Peter Vandekerckhove
Jan Spaas
A1
Journal Article
in
STEM CELLS INTERNATIONAL
2019
Equine allogeneic chondrogenic induced mesenchymal stem cells are an effective treatment for degenerative joint disease in horses
Sarah Y. Broeckx
Bert Seys
Marc Suls
Aurélie Vandenberghe
Tom Mariën
Edouard Adriaensen
Jeroen Declercq
Lore Van Hecke
Gabriele Braun
Klaus Hellmann
et al.
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2019
The use of equine chondrogenic‐induced mesenchymal stem cells as a treatment for osteoarthritis : a randomised, double‐blinded, placebo‐controlled proof‐of‐concept study
Sarah Broeckx
Ann Martens
AL Bertone
Leen Van Brantegem
Luc Duchateau
L Van Hecke
Michèle Dumoulin
Maarten Oosterlinck
Koen Chiers
H Hussein
et al.
A1
Journal Article
in
EQUINE VETERINARY JOURNAL
2019
2018
Allogeneic mesenchymal stem cells improve the wound healing process of sheep skin
T Martinello
C Gomiero
A Perazzi
I Lacopetti
F Gemignani
GM DeBenedictis
S Ferro
M Zuin
E Martines
P Brun
et al.
A1
Journal Article
in
BMC VETERINARY RESEARCH
2018
Equine allogeneic chondrogenic induced mesenchymal stem cells : a GCP target animal safety and biodistribution study
SY Broeckx
Jan Spaas
Koen Chiers
Luc Duchateau
Lore Van Hecke
Leen Van Brantegem
Michèle Dumoulin
Ann Martens
Frederik Pille
A1
Journal Article
in
RESEARCH IN VETERINARY SCIENCE
2018
2017
Tenogenically induced allogeneic peripheral blood mesenchymal stem cells in allogeneic platelet-rich plasma : 2-year follow-up after tendon or ligament treatment in horses
Charlotte Beerts
Marc Suls
Sarah Broeckx
Bert Seys
Aurelie Vandenberghe
Jeroen Declercq
Luc Duchateau
Martin A Vidal
Jan Spaas
A1
Journal Article
in
FRONTIERS IN VETERINARY SCIENCE
2017
2016
Equine-induced pluripotent stem cells retain lineage commitment toward myogenic and chondrogenic fates
Mattia Quattrocelli
Giorgia Giacomazzi
Sarah Broeckx
Liesbeth Ceelen
Selin Bolca
Jan Spaas
Maurilio Sampaolesi
A1
Journal Article
in
STEM CELL REPORTS
2016
Tenogenic induction of equine mesenchymal stem cells by means of growth factors and low-level laser technology
Chiara Gomiero
Giulia Bertolutti
Tiziana Martinello
Nathalie Van Bruaene
Sarah Broeckx
Marco Patruno
Jan Spaas
A1
Journal Article
in
VETERINARY RESEARCH COMMUNICATIONS
2016
Wound-healing markers after autologous and allogeneic epithelial-like stem cell treatment
Jan Spaas
Chiara Gomiero
Sarah Broeckx
Lore Van Hecke
Lisa Maccatrozzo
Ann Martens
Tiziana Martinello
Marco Patruno
A1
Journal Article
in
CYTOTHERAPY
2016
2015
Chondrogenic priming at reduced cell density enhances cartilage adhesion of equine allogeneic MSCs : a loading sensitive phenomenon in an organ culture study with 180 explants
Jan Spaas
Sarah Y Broeckx
Koen Chiers
Stephen J Ferguson
Marco Casarosa
Nathalie Van Bruaene
Ramses Forsyth
Luc Duchateau
Alfredo Franco-Obregon
Karin Wuertz-Kozak
A1
Journal Article
in
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
2015
Comparison of autologous versus allogeneic epithelial-like stem cell treatment in an in vivo equine skin wound model
Sarah Broeckx
Bizunesh Mideksa Borena
Lore Van Hecke
Koen Chiers
Sofie Maes
Deborah J Guest
Evelyne Meyer
Luc Duchateau
Ann Martens
Jan Spaas
A1
Journal Article
in
CYTOTHERAPY
2015
Regenerative skin wound healing in mammals : state-of-the-art on growth factor and stem cell based treatments
Bizunesh Mideksa Borena
Ann Martens
Sarah Broeckx
Evelyne Meyer
Koen Chiers
Luc Duchateau
Jan Spaas
A1
Journal Article
in
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
2015
Tenogenically induced allogeneic mesenchymal stem cells for the treatment of proximal suspensory ligament desmitis in a horse
Aurélie Vandenberghe
Sarah Y. Broeckx
Charlotte Beerts
Bert Seys
Marieke Zimmerman
Ineke Verweire
Marc Suls
Jan Spaas
A1
Journal Article
in
FRONTIERS IN VETERINARY SCIENCE
2015
2014
Allogenic mesenchymal stem cells as a treatment for equine degenerative joint disease : a pilot study
Sarah Broeckx
Marc Suls
Charlotte Beerts
Aurélie Vandenberghe
Bert Seys
Karin Wuertz-Kozak
Luc Duchateau
Jan Spaas
A1
Journal Article
in
CURRENT STEM CELL RESEARCH & THERAPY
2014
Correlation between dichromatic colour vision and jumping performance in horses
Julie Spaas
Werner F Helsen
Maurits Adriaenssens
Sarah Broeckx
Luc Duchateau
Jan Spaas
A1
Journal Article
in
VETERINARY JOURNAL
2014
Equine epidermis : a source of epithelial-like stem/progenitor cells with in vitro and in vivo regenerative capacities
Sarah Broeckx
Sofie Maes
Tiziana Martinello
Désirée Aerts
Koen Chiers
Tom Mariën
Marco Patruno
Alfredo Franco-Obregón
Jan Spaas
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2014
Intravenous application of allogenic peripheral blood-derived mesenchymal stem cells : a safety assessment in 291 equine recipients
Sarah Broeckx
Bizunesh Mideksa Borena
Marieke Zimmerman
Tom Mariën
Bert Seys
Marc Suls
Luc Duchateau
Jan Spaas
A1
Journal Article
in
CURRENT STEM CELL RESEARCH & THERAPY
2014
Regenerative therapies for equine degenerative joint disease : a preliminary study
Sarah Broeckx
Marieke Zimmerman
Sara Crocetti
Marc Suls
Tom Mariën
Stephen J Ferguson
Koen Chiers
Luc Duchateau
Alfredo Franco-Obregón
Karin Wuertz
et al.
A1
Journal Article
in
PLOS ONE
2014
Sphere-forming capacity as an enrichment strategy for epithelial-like stem cells from equine skin
Bizunesh Mideksa Borena
Evelyne Meyer
Koen Chiers
Ann Martens
Kristel Demeyere
Sarah Broeckx
Luc Duchateau
Jan Spaas
A1
Journal Article
in
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
2014
2013
Culture and characterisation of equine peripheral blood mesenchymal stromal cells
Jan Spaas
Catharina De Schauwer
Pieter Cornillie
Evelyne Meyer
Ann Van Soom
Gerlinde Van de Walle
A1
Journal Article
in
VETERINARY JOURNAL
2013
Equine peripheral blood- and mammary gland-derived multipotent stem cells : an update on their characterization and potential
Jan Spaas
Gerlinde Van de Walle
Ann Van Soom
Dissertation
2013
The effects of equine peripheral blood stem cells on cutaneous wound healing: a clinical evaluation in four horses
Jan Spaas
Sarah Broeckx
Gerlinde Van de Walle
Marco Polettini
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL DERMATOLOGY
2013
2012
Stem/progenitor cells in non-lactating versus lactating equine mammary gland
Jan Spaas
Koen Chiers
Leen Bussche
Christian Paul G. Burvenich
Gerlinde Van de Walle
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2012
Tendon regeneration in human and equine athletes : ubi sumus-quo vadimus (where are we and where are we going to)?
Jan Spaas
Deborah Guest
Gerlinde Van de Walle
A1
Journal Article
in
SPORTS MEDICINE
2012
Treatment of equine degenerative joint disease with autologous peripheral blood-derived mesenchymal stem cells: a case report
Jan Spaas
Maarten Oosterlinck
Sarah Broeckx
Michèle Dumoulin
Jimmy Saunders
Ann Van Soom
Frederik Pille
Gerlinde Van de Walle
A1
Journal Article
in
VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT
2012
2011
Purification and expansion of stem cells from equine peripheral blood, with clinical applications
Jan Spaas
Alessandra Gambacurta
Marco Polettini
Sarah Broeckx
Frank Van Hoeck
Catharina De Schauwer
Gerlinde Van de Walle
Ann Van Soom
A1
Journal Article
in
VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT
2011
Relatie tussen huisvesting en fysieke gezondheidsproblemen van paarden: een enquête over de perceptie van paardeneigenaars
Sarah Broeckx
Piet Deprez
Jan Govaere
Jan Spaas
J Christiaens
Dominiek Maes
A1
Journal Article
in
VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT
2011
Ultrasound prediction of the partus datum in dogs
PA de Wispelaere
Ann Van Soom
Tom Rijsselaere
Jimmy Saunders
G Storms
Dieter Verdonck
Eva Vandermeulen
C De Sadeleer
A Dobbeleir
Hamphrey Ham
et al.
A1
Journal Article
in
TIJDSCHRIFT VOOR DIERGENEESKUNDE
2011