Research Explorer

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Researcher

Jan Philippé

Publications & Research Data

Awards & Distinctions

251 Results

2025

Novel flow cytometric antibody panel and dedicated analysis algorithm for automated fully standardized minimal residual disease detection in chronic lymphocytic leukemia

Robby EngelmannJuan Flores‐MonteroJoyce Schilperoord‐VermeulenMatthias RitgenPaul J. HengeveldSaskia KohlscheenGeorgiana GrigoreRafael Fluxa RodriguezQuentin LecrevisseJan Philippé et al.

A1 Journal Article in AMERICAN JOURNAL OF HEMATOLOGY

Unraveling genotype–phenotype associations and predictive modeling of outcome in acute myeloid leukemia

Artuur CouckuytSofie Van GassenAnnelies EmmaneelVince JandaMalicorne BuysseIne MoorsJan PhilippéMattias HofmansTessa KerreYvan Saeys et al.

A1 Journal Article in CYTOMETRY PART B-CLINICAL CYTOMETRY

2024

HES6 knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells

Tamara De VosNicole OatmanLena BoehmeTom PuttemanImke VelgheYana Van DroogenbroeckStijn De MunterMichaela CesnekovaFilip Van NieuwerburghBart Vandekerckhove et al.

A1 Journal Article in HAEMATOLOGICA

New molecular drivers and cell surface markers that characterize normal human hematopoiesis

Tamara De VosTom TaghonJan Philippé

Phenotypic profiling of CD34+ cells by advanced flow cytometry improves diagnosis of juvenile myelomonocytic leukemia

Cristina BugarinLaura AntoliniChiara BuracchiSergio MatarrazTiziana Angela ColivaVincent H. Van der VeldenTomasz SzczepanskiElaine Sobral Da CostaAlita Van der SluijsMichaela Novakova et al.

A1 Journal Article in HAEMATOLOGICA

2023

Baseline immunophenotypic profile of bone marrow leukemia cells in acute myeloid leukemia with nucleophosmin-1 gene mutation : a EuroFlow study

Sergio MatarrazPilar LeozAna Yeguas-BermejoVincent van der VeldenAnne E. BrasJose I. Sánchez GallegoQuentin LecrevisseRosa Ayala-BuenoCristina TeodosioIgnacio Criado et al.

A1 Journal Article in BLOOD CANCER JOURNAL

2022

Anemia and its association with asymptomatic malaria, iron and zinc deficiencies, and ferroportin Q248H mutation in children aged under 5 years in South Kivu/Democratic Republic of Congo

Yvette Lufungulo BahatiJoris DelangheJan PhilippéGhislain Bisimwa Balaluka

Deciphering the non-coding landscape of pediatric acute myeloid leukemia

Laurens Van CampJolien VanhoorenBarbara DepreterMartijn de JongAnne UyttebroeckAn Van DammeLaurence DedekenMarie-Françoise DresseJutte van der Werff ten BoschMattias Hofmans et al.

Deciphering the non-coding landscape of pediatric acute myeloid leukemia

Jolien VanhoorenLaurens Van CampBarbara DepreterMartijn de JongAnne UyttebroeckAn Van DammeLaurence DedekenMarie-Françoise DresseJutte van der Werff ten BoschMattias Hofmans et al.

Deciphering the non-coding RNA landscape of pediatric acute myeloid leukemia

Jolien VanhoorenLaurens Van CampBarbara DepreterMartijn de JongAnne UyttebroeckAn Van Van DammeLaurence DedekenMarie-Françoise DresseJutte van der Werff ten BoschMattias Hofmans et al.

A1 Journal Article in CANCERS

Expert-independent classification of mature B-cell neoplasms using standardized flow cytometry : a multicentric study

Sebastian BöttcherRobby EngelmannGeorgiana GrigorePaula Carolina FernandezJoana CaetanoJuan Flores-MonteroVincent H.J. van der VeldenMichaela NovakovaJan PhilippéMatthias Ritgen et al.

A1 Journal Article in BLOOD ADVANCES

Exploration of the relationship between anemia and iron and zinc deficiencies in children under 5 years of age living in the malaria endemic area of South Kivu/Democratic Republic of Congo

Yvette Lufungulo BahatiJoris DelangheGhislain Bisimwa BalalukaJan Philippé

A1 Journal Article in ANNALS OF HEMATOLOGY

Ferroportin Q248H mutation was not found to be protective against malaria and anemia in children under 5 years living in South Kivu/Democratic Republic of Congo, an endemic area of Plasmodium infection

Yvette Lufungulo BahatiJoris DelangheGhislain Bisimwa BalalukaKarl VandepoeleJustin Cikomola CirhuzaAntoine Sadiki KishabongoJan Philippé

A1 Journal Article in HELIYON

Flow cytometric minimal residual disease assessment in B‐cell precursor acute lymphoblastic leukaemia patients treated with CD19‐targeted therapies : a EuroFlow study

Martijn W. C. VerbeekChiara BuracchiAnna LaquaStefan NierkensLukasz SedekJuan Flores‐MonteroMattias HofmansElaine Sobral de CostaMichaela NovákováEster Mejstrikova et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Immunophenotypic analysis of acute megakaryoblastic leukemia : a EuroFlow study

Nienke BrouwerSergio MatarrazStefan NierkensMattias HofmansMichaela NovákováElaine Sobral da CostaPaula FernandezAnne E. BrasFabiana Vieira de MelloEster Mejstrikova et al.

A1 Journal Article in CANCERS

Impact of pre-analytical and analytical variables associated with sample preparation on flow cytometric stainings obtained with EuroFlow panels

Łukasz SędekJuan Flores-MonteroAlita van der SluijsJan KulisJeroen te MarveldeJan PhilippéSebastian BöttcherMarieke BitterJoana CaetanoVincent H. J. van der Velden et al.

A1 Journal Article in CANCERS

Quality assessment of a large multi-center flow cytometric dataset of acute myeloid leukemia patients : a EuroFlow study

Anne E. BrasSergio MatarrazStefan NierkensPaula FernándezJan PhilippéCarmen-Mariana AaneiFabiana Vieira de MelloLeire BurgosAlita J. van der Sluijs-GellingGeorgiana Emilia Grigore et al.

A1 Journal Article in CANCERS

Technical aspects of flow cytometry-based measurable residual disease quantification in acute myeloid leukemia : experience of the European LeukemiaNet MRD Working Party

Jesse M. TetteroSylvie FreemanVeit BueckleinAdriano VendittiLuca MaurilloWolfgang KernRoland B. WalterBrent L. WoodChristophe RoumierJan Philippé et al.

A1 Journal Article in HEMASPHERE

The Euroflow PID Orientation Tube in the diagnostic workup of primary immunodeficiency : daily practice performance in a tertiary university hospital

Jana NeirinckAnnelies EmmaneelMalicorne BuysseJan PhilippéSofie Van GassenYvan SaeysXavier BossuytStefanie De BuyserMirjam van der BurgMartin Perez-Andres et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2021

2021 update on MRD in acute myeloid leukemia : a consensus document from the European LeukemiaNet MRD Working Party

Michael HeuserSylvie D FreemanGert J OssenkoppeleFrancesco BuccisanoChristopher S HouriganLok Lam NgaiJesse Marc TetteroCosta BachasConstance BaerMarie C Béné et al.

A1 Journal Article in BLOOD

CircRNAs dysregulated in juvenile myelomonocytic leukemia : CircMCTP1 stands out

Anna Dal MolinMattias HofmansEnrico GaffoAlessia BuratinHélène CavéChristian FlothoValerie de HaasCharlotte M. NiemeyerJan StaryPieter Van Vlierberghe et al.

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Deciphering molecular heterogeneity in pediatric AML using a cancer vs. normal transcriptomic approach

Barbara DepreterBarbara De MoerlooseKarl VandepoeleAnne UyttebroeckAn Van DammeEva TerrasBarbara DenysLaurence DedekenMarie-Francoise DresseJutte Van der Werff Ten Bosch et al.

A1 Journal Article in PEDIATRIC RESEARCH

Dissection of the pre-germinal center B-cell maturation pathway in common variable immunodeficiency based on standardized flow cytometric euroflow tools

Lucía del Pino-MolinaEduardo López-GranadosQuentin LecrevisseJuan Torres CanizalesMartín Pérez-AndrésElena BlancoMarjolein WentinkCarolien BonroyJana NechvatalovaTomas Milota et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Immunoglobulin g subclass and specific polysaccharide antibody deficiency : a clinical and immunological profile in a tertiary cohort

Levi HosteJudith ClausSimon SchelfhoutJarno De CraemerLaurens De KetelaereDelfien BogaertCarolien BonroyJan PhilippéJulie WillekensTessa Kerre et al.

Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensBarbara DepreterYing WuMiriam ErlacherAurélie CayeHélène CavéChristian FlothoValerie de HaasCharlotte M. Niemeyer et al.

A1 Journal Article in SCIENTIFIC REPORTS

Novel therapeutic targets in juvenile myelomonocytic leukaemia : are noncoding RNAs valuable treatment options?

Mattias HofmansTim LammensJan PhilippéBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Novel therapeutic targets in juvenile myelomonocytic leukemia : are noncoding RNAs valuable treatment options?

Mattias HofmansBarbara De MoerlooseJan PhilippéTim Lammens

TARP as antigen in cancer immunotherapy

Jolien VanhoorenCharlotte DerpoorterBarbara DepreterLarissa DenewethJan PhilippéBarbara De MoerlooseTim Lammens

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY

2020

A challenging diagnosis of a nonsecretor plasma cell dyscrasia with pleomorphic plasmablastic morphology

Stijn Van LandeghemSara CapiauJean‐Louis BayartPhilip VlummensJo Van DorpeNadine Van RoyJan Philippé

A2 Journal Article in CLINICAL CASE REPORTS

Asymptomatic submicroscopic plasmodium infection is highly prevalent and is associated with anemia in children younger than 5 years in South Kivu/Democratic Republic of Congo

Yvette Lufungulo BahatiJoris DelangheGhislain Bisimwa BalalukaAntoine Sadiki KishabongoJan Philippé

A1 Journal Article in AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Clinical significance of TARP expression in pediatric acute myeloid leukemia

B. DepreterBarbara De MoerlooseKarl VandepoeleA. UyttebroeckA. Van DammeB. DenysL. DedekenM. -F. DresseJ. Van der Werff Ten BoschM. Hofmans et al.

Clinical significance of TARP expression in pediatric acute myeloid leukemia

Barbara DepreterBarbara De MoerlooseKarl VandepoeleAnne UyttebroeckAn Van DammeBarbara DenysLaurence DedekenMarie-Françoise DresseJutte Van Der Werff Ten BoschMattias Hofmans et al.

A1 Journal Article in HEMASPHERE

Decreased DNA double‑strand break repair and enhanced chromosomal radiosensitivity in irradiated non‑tumorigenic human breast epithelial cells with a partial BRCA1 or BRCA2 knockdown

Annelot BaertMaria PalermoMattias Van HeetveldeBram VerstraeteJulie DepuydtJeroen VierstraeteJan PhilippéAnna SablinaGianpaolo PerlettiKathleen Claes et al.

A2 Journal Article in WORLD ACADEMY OF SCIENCES JOURNAL

EuroFlow standardized approach to diagnostic immunopheneotyping of severe PID in newborns and young children

Tomas KalinaMarina BakardjievaMaartje BlomMartin Perez-AndresBarbara BarendregtVeronika KanderováCarolien BonroyJan PhilippéElena BlancoIngrid Pico-Knijnenburg et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Exploring the molecular and phenotypical heterogeneity between patients with pediatric acute myeloid leukemia

Barbara DepreterTim LammensJan Philippé

Improved standardization of flow cytometry diagnostic screening of primary immunodeficiency by software-based automated gating

Eleni LinskensAM DiksJana NeirinckM Perez-AndresEmilie De MaertelaereMA BerkowskaTessa KerreMattias HofmansA Orfaovan Dongen JJM et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Leukaemic stem cells in AML : where are we now? An update on recent findings and detection

Barbara DepreterBarbara De MoerlooseJan PhilippéTim Lammens

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Retrospective analysis of the incidence and characteristics of paediatric myelodysplastic syndrome and juvenile myelomonocytic leukaemia in Belgium

Lindsey De SmaeleMattias HofmansTim LammensA Van DammeJutte van der Werff ten BoschA FersterJoris VerlooyC ChantrainJan PhilippéNadine Van Roy et al.

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Barbara DepreterKarin WeeningKarl VandepoeleMagnus EssandBarbara De MoerlooseMaria ThemeliJacqueline CloosDiana HanekampIne MoorsINGE D'HONT et al.

A1 Journal Article in HAEMATOLOGICA

2019

A case report of acute panmyelosis with myelofibRosis (APMF) with a distinct molecular pattern

Emilie De MaertelaereKarl VandepoeleJoni Van der MeulenIne MoorsWillem DaneelsAnke DelieJan PhilippéCarolien BonroyKatrien DevreeseNadine Van Roy et al.

Clinical implications of measurable residual disease in AML : review of current evidence

Ine MoorsKarl VandepoeleJan PhilippéDries DeerenDominik SelleslagDimitri BreemsNicole StraetmansTessa KerreBarbara Denys

A1 Journal Article in CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Barbara DepreterMattias HofmansEva TerrasAnne UyttebroeckAn Van DammeAlina FersterJutte Van der Werff Ten BoschMarie-Françoise DresseKarl VandepoeleBarbara De Moerloose et al.

Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Barbara DepreterMattias HofmansEva TerrasAnne UyttebroeckAn Van DammeAlina FersterJutte van der Werff ten BoschMarie-Françoise DresseKarl VandepoeleBarbara De Moerloose et al.

Defects in memory B-cell and plasma cell subsets expressing different immunoglobulin-subclasses in patients with CVID and immunoglobulin subclass deficiencies

Elena BlancoMartín Pérez-AndrésSonia Arriba-MéndezCristina SerranoIgnacio CriadoLucía Del Pino-MolinaSusana SilvaIgnacio MadrugaMarina BakardjievaCatarina Martins et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

EuroFlow-based flowcytometric diagnostic screening and classification of primary immunodeficiencies of the lymphoid system

van Dongen JJMM van der BurgT KalinaM Perez-AndresE MejstrikovaM VlkovaE Lopez-GranadosM WentinkAK KienzlerJan Philippé et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Immunoglobulin g subclass and specific polysaccharide antibody deficiency : a clinical and immunological profile in a tertiary cohort

Levi HosteJudith ClausSimon SchelfhoutJarno De CraemerLaurens De KetelaereDelfien BogaertCarolien BonroyJan PhilippéJulie WillekensTessa Kerre et al.

Impact of blood storage and sample handling on quality of high dimensional flow cytometric data in multicenter clinical research

AM DiksCarolien BonroyC TeodosioRJ GroenlandB de MooijEmilie De MaertelaereJana NeirinckJan PhilippéA OrfaoJJM van Dongen et al.

A1 Journal Article in JOURNAL OF IMMUNOLOGICAL METHODS

Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia : proof of concept study

Mattias HofmansBarbara DepreterTim LammensHelene CaveChristian FlothoHenrik HasleValerie de HaasCharlotte M. NiemeyerJan StaryPieter Van Vlierberghe et al.

Noonan syndrome-associated myeloproliferative disorder with somatically acquired monosomy 7 : impact on clinical decision making

Mattias HofmansRieke SchroederTim LammensChristian FlothoCharlotte NiemeyerNadine Van RoyWim DecaluweJan PhilippéBarbara De Moerloose

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Optimization and testing of dried antibody tube : the EuroFlow LST and PIDOT tubes as examples

Vincent H.J. van der VeldenJuan Flores-MonteroMartin Perez-AndresMarta Martin-AyusoOliver CrespoElena BlancoTomas KalinaJan PhilippéCarolien BonroyMaaike de Bie et al.

A1 Journal Article in JOURNAL OF IMMUNOLOGICAL METHODS

TARP as immunotherapeutic target in AML expressed in the LSC compartment

Barbara DepreterKarin WeeningKarl VandepoeleM EssandBarbara De MoerlooseM ThemeliJ CloosD HanekampIne MoorsINGE D'HONT et al.

2018

A case of chronic eosinophilic leukemia with secondary transformation to acute myeloid leukemia

Mattias HofmansAnke DelieKarl VandepoeleNadine Van RoyJoni Van der MeulenJan PhilippéIne Moors

A2 Journal Article in LEUKEMIA RESEARCH REPORTS

Cancer-related mRNA expression analysis using a novel flow cytometry-based assay

Barbara DepreterJan PhilippéMAGALI MEULBarbara DenysKarl VandepoeleBarbara De MoerlooseTim Lammens

A1 Journal Article in CYTOMETRY PART B-CLINICAL CYTOMETRY

Exploring the long non-coding RNA landscape in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensS BresolinH CavéC FlothoH HasleHetty HelsmoortelM Van den Heuvel-EibrinkC NiemeyerJ Stary et al.

Leukaemic stem cell load at diagnosis predicts the development of relapse in young acute myeloid leukaemia patients

Diana HanekampBarbara DenysGertjan JL KaspersJeroen G te MarveldeGerrit Jan SchuurhuisValerie De HaasBarbara De MoerlooseEveline S de BontC Michel ZwaanAnja de Jong et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Predisposing mutations in hippo signaling reveal an actionable target in Burkitt lymphoma

Charlotte DerpoorterKatrien VandemeulebroeckeTieneke BautersJan PhilippéGenevieve LaureysTim Lammens

RNA-based FLT3-ITD allelic ratio is associated with outcome and ex vivo response to FLT3 inhibitors in pediatric AML

David G. J. CucchiBarbara DenysGertjan J. L. KaspersJeroen J. W. M. JanssenGert J. OssenkoppeleValerie de HaasC. Michel ZwaanMarry M. van den Heuvel-EibrinkJan PhilippéTamas Csikos et al.

A1 Journal Article in BLOOD

The light chain IgLV3-21 defines a new poor prognostic subgroup in chronic lymphocytic leukemia : results of a multicenter study

Basile StamatopoulosThomas SmithEmerence CrompotKarlien PietersRuth CliffordMarek MrazPauline RobbeAdam BurnsAdele TimbsDavid Bruce et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

The long non-coding RNA landscape in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensHetty HelsmoortelSilvia BresolinHélène CavéChristian FlothoHenrik HasleMarry M van den Heuvel-EibrinkCharlotte NiemeyerJan Stary et al.

A1 Journal Article in HAEMATOLOGICA

2017

A case report of a paediatric early T-cell precursor lymphoblastic leukemia

ANNE-SOPHIE DE KONINCKCatharina DhoogeBarbara DenysKarl VandepoeleNadine Van RoyMattias HofmansJan Philippé

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Diagnostic performance of the loop-mediated isothermal amplification (LAMP) based illumigene (R) malaria assay in a non-endemic region

ANNE-SOPHIE DE KONINCKLieselotte CnopsMattias HofmansJan JacobsDorien Van den BosscheJan Philippé

A1 Journal Article in MALARIA JOURNAL

The immunophenotypic fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Delfien BogaertMarieke De BruyneVeronique DebackerPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéMaria Bordon Cueto De BraemBart LambrechtTessa Kerre et al.

A1 Journal Article in HAEMATOLOGICA

The immunophenotypical fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Delfien BogaertMarieke De BruyneVeronique DebackerPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéMaria Bordon Cueto De BraemBart LambrechtTessa Kerre et al.

2016

Comparison between FLT3-ITD measurements based on RNA and DNA of childhood myeloid leukemia samples

Edwin SonneveldValerie de HaasMichel ZwaanMarry van den Heuvel-EibrinkJan PhilippéBarbara DenysBarbara De MoerlooseEveline de BontGert Jan KaspersJacqueline Cloos

In vitro cellular radiosensitivity in relationship to late normal tissue reactions in breast cancer patients : a multi-endpoint case-control study

Charlot VandevoordeJulie DepuydtLiv VeldemanWilfried De NeveNatividad SebastiaGreet WiemeAnnelot BaertSofie De LangheJan PhilippéHubert Thierens et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Hetty HelsmoortelSilvia BresolinTim LammensHélène CavéPeter NoellkeAurélie CayeFarzaneh GhazaviAndrica de VriesHenrik HasleVeerle Labarque et al.

A1 Journal Article in BLOOD

Lipoprotein lipase in chronic lymphocytic leukemia : function and prognostic implications

Ans RomboutBruno VerhasseltJan Philippé

A1 Journal Article in EUROPEAN JOURNAL OF HAEMATOLOGY

Mimicking the tumour microenvironment of chronic lymphocytic leukaemia in vitro critically depends on the type of B-cell receptor stimulation

Ans RomboutSofie LustFritz OffnerEvelien NaessensBruno VerhasseltJan Philippé

A1 Journal Article in BRITISH JOURNAL OF CANCER

Radiation sensitivity of human CD34+ cells versus peripheral blood T lymphocytes of newborns and adults: DNA repair and mutagenic effects

Charlot VandevoordeAnne VralBart VandekerckhoveJan PhilippéHubert Thierens

A1 Journal Article in RADIATION RESEARCH

The immunophenotypical landscape of patients with primary antibody deficiencies and their asymptomatic first-degree relatives : arguments for a multifactorial aetiology

Delfien BogaertPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéMaria Bordon Cueto De BraemTessa KerreBart LambrechtAndrea CeruttiKarim Vermaelen et al.

2015

CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol

Farzaneh GhazaviEmmanuelle ClappierTim LammensStefan SuciuAurélie CayeSamira ZegrariMarleen BakkusNathalie GrardelYves BenoitOdile Minckes et al.

A1 Journal Article in HAEMATOLOGICA

Comparison of methods for in-house screening of HLA*B57:01 to prevent abacavir hypersensitivity in HIV-1 care

Ward De SpiegelaereJan PhilippéKAREN VERVISCHChris VerhofstedeEva MalatinkováMaja KiselinovaWim TrypsteenPawel BonczkowskiDirk VogelaersSteven Callens et al.

A1 Journal Article in PLOS ONE

Functional exploration of ZAP70 and LPL in chronic lymphocytic leukemia

Ans RomboutJan PhilippéBruno Verhasselt

Glycated nail proteins as a new biomarker in management of the South Kivu Congolese diabetics

Philippe B KatchungaPatrick N MirindiAntoine S KishabongoJustin C CikomolaSocrate BwanamdogoJan PhilippéMarijn SpeeckaertJoris Delanghe

A1 Journal Article in BIOCHEMIA MEDICA

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

Stijn VanheeKatrien De MulderYasmine Van CaeneghemGreet VerstichelNadine Van RoyBjörn MentenImke VelgheJan PhilippéDominique De BleserBart Lambrecht et al.

A1 Journal Article in HAEMATOLOGICA

Lipoprotein lipase SNPs rs13702 and rs301 correlate with clinical outcome in chronic lymphocytic leukemia patients

Ans RomboutBasile StamatopoulosLaurence LagneauxSofie LustFritz OffnerEvelien NaessensHanne VanderstraetenBruno VerhasseltJan Philippé

A1 Journal Article in PLOS ONE

Mimicking the tumor microenvironment of chronic lymphocytic leukemia in vitro critically depends on the type of B cell receptor stimulation

Ans RomboutSofie LustFritz OffnerEvelien NaessensBruno VerhasseltJan Philippé

The long non-coding RNA H19 is regulated by LIN28B

Hetty HelsmoortelBarbara De MoerlooseTim PietersFarzaneh GhazaviS BresolinH CavéA CayeACH de VriesC FlothoV Labarque et al.

The relevance of stem cell load at diagnosis for the development of relapse in pediatric acute myeloid leukemia

Dirkje W HanekampBarbara DenysGerjan JL SchuurhuisJeroen G te MarveldeValerie de HaasBarbara De MoerlooseEveline S de BontAnja de JongJan PhilippéJacqueline Cloos et al.

The YPEL5-PPP1CB fusion transcript is detected in different hematological malignancies and in normal samples

Karl VandepoeleJan PhilippéBarbara Denys

A2 Journal Article in LEUKEMIA RESEARCH REPORTS

2014

In vitro human embryonic stem cell hematopoiesis mimics MYB independent yolk sac hematopoiesis

Stijn VanheeKatrien De MulderYasmine Van CaeneghemNadine Van RoyBjörn MentenImke VelgheJan PhilippéTom TaghonGeorges LeclercqTessa Kerre et al.

Juvenile myelomonocytic leukaemia: the quest for more specific therapies

Hetty HelsmoortelTim LammensNadine Van RoyJan PhilippéPascale De PaepeYves BenoitFranki SpelemanPieter Van VlierbergheBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Prognostic relevance of CD200/BTLA deletions in pediatric precursor-B cell acute lymphoblastic leukemia treated according to the EORTD-CLG 58951 protocol

Farzaneh GhazaviTim LammensEmmanuelle ClappierStefan SuciuAurélie CayeSamira ZegrariMarleen BakkusNathalie GrardelYves BenoitYves Bertrand et al.

The prognostic value of leukemic stem cells in pediatric AML

Bram De CaluwéRolf WoutersValerie De HaasJeroen G te MarveldeBarbara De MoerlooseEveline S de BontBarbara DenysAnja De JongG KaspersJan Philippé et al.

2013

CLL cells respond to B-cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression

Valerie PedeAns RomboutJOLIEN VERMEIREEvelien NaessensPieter MestdaghNore RobberechtHanne VanderstraetenNadine Van RoyJo VandesompeleFranki Speleman et al.

A1 Journal Article in PLOS ONE

ER stress in diffuse large B cell lymphoma: GRP94 is a possible biomarker in germinal center versus activated B-cell type

Jerina BoelensJean-Philippe JaisBarbara VanhoeckeIlse BeckHeleen Van MelckebekeJan PhilippéMarc BrackeFabrice JardinJosette BrièreKaren Leroy et al.

A1 Journal Article in LEUKEMIA RESEARCH

Expression of ZAP70 in chronic lymphocytic leukaemia activates NF-κB signalling

Valerie PedeAns RomboutJOLIEN VERMEIREEvelien NaessensHanne VanderstraetenJan PhilippéBruno Verhasselt

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Ferroportin Q248H mutation, hyperferritinemia and atypical type 2 diabetes mellitus in South Kivu

Philippe Bianga KatchungaMarius BagumaJean René M'Buyamba-KabanguJan PhilippéMichel P HermansJoris Delanghe

A2 Journal Article in DIABETES & METABOLIC SYNDROME. CLINICAL RESEARCH & REVIEWS

Improved flow cytometric detection of minimal residual disease in childhood acute lymphoblastic leukemia

B DenysAJ van der Sluijs-GellingC HomburgCE van der SchootV De HaasJan PhilippéR PietersJ van DongenVHJ van der Velden

A1 Journal Article in LEUKEMIA

In vitro apoptosis and clonal evolution in chronic lymphocytic leukemia : predictive value and possible influence on treatment

Ann JanssensFritz OffnerJan Philippé

Latent Transforming growth factor Binding Protein 2 (LTBP2) is related to phenotypic changes suggestive for HFPEF in stable outpatients with coronary artery disease and preserved ejection fraction

Johan De SutterSofie PardaensD Van HerckeN Van De VeireMarc De BuyzereJan PhilippéG VanpouckeG Thomas

PF-4var/CXCL4L1 predicts outcome in stable coronary artery disease patients with preserved left ventricular function

Johan De SutterN Van De VeireS StruyfJan PhilippéMarc De BuyzereJ Van Damme

2012

Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating serum hepcidin levels in Rwandese HIV-positive women

Florence MasaisaCandace BremanJean Bosco GahutuJoshua MukiibiJoris DelangheJan Philippé

A1 Journal Article in ANNALS OF HEMATOLOGY

Function and prognostic relevance of ZAP-70 and LPL in chronic lymphocytic leukemia

Valerie PedeBruno VerhasseltJan Philippé

High-risk clonal evolution in chronic B-lymphocytic leukemia: single-center interphase fluorescence in situ hybridization study and review of the literature

Ann JanssensNadine Van RoyBruce PoppeLucien NoensJan PhilippéFranki SpelemanFritz Offner

A1 Journal Article in EUROPEAN JOURNAL OF HAEMATOLOGY

Isolation of disseminated neuroblastoma cells from bone marrow aspirates for pretreatment risk assessment by array comparative genomic hybridization

Mado VandewoestyneCandy KumpsKatrien SwertsBjörn MentenTim LammensJan PhilippéKatleen De PreterGenevieve LaureysNadine Van RoyFranki Speleman et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

N-Cadherin in neuroblastoma disease : expression and clinical significance

Tim LammensKatrien SwertsLara DeryckeANNEMIE DE CRAEMERSara De BrouwerKatleen De PreterNadine Van RoyJo VandesompeleFranki SpelemanJan Philippé et al.

A1 Journal Article in PLOS ONE

PF-4var/CXCL4L1 predicts outcome in stable coronary artery disease patients with preserved left ventricular function

Johan De SutterNico R van de VeireSofie StruyfJan PhilippéMarc De BuyzereJo Van Damme

A1 Journal Article in PLOS ONE

RHAMM/HMMR (CD168) is not an ideal target antigen for immunotherapy of acute myeloid leukemia

SYLVIA SNAUWAERTStijn VanheeGlenn GoetgelukGreet VerstichelYasmine Van CaeneghemImke VelgheJan PhilippéZwi N BernemanJean PlumTom Taghon et al.

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

Screening for hereditary spherocytosis in routine practice : evaluation of a diagnostic algorithm with focus on non-splenectomised patients

Lies PersijnCarolien BonroyVeerle MondelaersANNA VANTILBORGHJan PhilippéVeronique Stove

A1 Journal Article in ANNALS OF HEMATOLOGY

Transferrin polymorphism and opportunistic infections in HIV-infected women in Rwanda

Florence MasaisaJean Bosco GahutuJoshua MukiibiJoris DelangheJan Philippé

A1 Journal Article in ACTA HAEMATOLOGICA

2011

Anemia in human immunodeficiency virus-infected and uninfected women in Rwanda

Florence MasaisaJean Bosco GahutuJoshua MukiibiJoris DelangheJan Philippé

A1 Journal Article in AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

An De WeerJoni Van der MeulenPieter RondouTom TaghonTorsten A KonradKatleen De PreterPieter MestdaghTom Van MaerkenNadine Van RoyMarta Jeison et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Laser microdissection for the assessment of the clonal relationship between chronic lymphocytic leukemia/small lymphocytic lymphoma and proliferating B cells within lymph node pseudofollicles

Mado VandewoestyneValerie PedeKathleen LambeinMaarten DhaenensFritz OffnerMarleen PraetJan PhilippéThomas J KippsDieter Deforce

A1 Journal Article in LEUKEMIA

2010

A real-time polymerase chain reaction assay for rapid, sensitive, and specific quantification of the JAK2V617F mutation using a locked nucleic acid-modified oligonucleotide

Barbara DenysHakim El HousniFriedel NolletBruno VerhasseltJan Philippé

A1 Journal Article in JOURNAL OF MOLECULAR DIAGNOSTICS

Cardiovascular determinants and prognostic significance of CC Chemokine Ligand-18 (CCL18/PARC) in patients with stable coronary artery disease

Johan De SutterS StruyfNRV de VeireJan PhilippéMarc De BuyzereJ Van Damme

A1 Journal Article in JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Early increase of radiation-induced γH2AX foci in a human Ku70/80 knockdown cell line characterized by an enhanced radiosensitivity

Veerle VandersickelJulie DepuydtBram Van BockstaeleGianpaolo PerlettiJan PhilippéHubert ThierensAnne Vral

A1 Journal Article in JOURNAL OF RADIATION RESEARCH

Impaired hemoglobin scavenging during an acute HIV-1 retroviral syndrome

Joris DelangheJan PhilippéFILIP MOERMANMarc De BuyzereLiesbeth L VynckierAlain VerstraeteDirk VogelaersLinos Vandekerckhove

A1 Journal Article in CLINICA CHIMICA ACTA

In vitro and in vivo evaluation of [99mTc]-labeled tricarbonyl His-annexin A5 as an imaging agent for the detection of phosphatidylserine-expressing cells

CHRISTEL VANGESTELMarc PeetersRuth OltenfreiterYves D'AsselerSteven StaelensMagali Van SteenkisteJan PhilippéDennis KustersChris ReutelingspergerNancy Van Damme et al.

A1 Journal Article in NUCLEAR MEDICINE AND BIOLOGY

Lentivirus-mediated RNA interference of Ku70 to enhance radiosensitivity of human mammary epithelial cells

Veerle VandersickelM ManciniE MarrasP WillemsJ SlabbertJan PhilippéEllen DeschepperHubert ThierensG PerlettiAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Microrna expression in pediatric precursor-B acute lymphoblastic leukemia: biology, classification and prognosis

Tim LammensBarbara De MoerlooseJonas Van BaelenJoni Van der MeulenPieter MestdaghBruno VerhasseltJan PhilippéFranki SpelemanYves Benoit

PHF6 mutations in T-cell acute lymphoblastic leukemia

Pieter Van VlierbergheTeresa PalomeroHossein KhiabanianJoni Van der MeulenMireia CastilloNadine Van RoyBarbara De MoerlooseJan PhilippéSara Gonzalez-GarciaMaria L Toribio et al.

A1 Journal Article in NATURE GENETICS

The flavonoid tangeretin activates the unfolded protein response and synergizes with imatinib in the erythroleukemia cell line K562

Sofie LustBarbara VanhoeckeMireille Van GeleJan PhilippéMarc BrackeFritz Offner

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

2009

A RAPID, SENSITIVE AND SPECIFIC REAL-TIME POLYMERASE CHAIN REACTION ASSAY FOR QUANTIFICATION OF THE JAK2V617F ALLELE BURDEN

B. DenysH El HousniF NolletBruno VerhasseltJan Philippé

Array comparative genomic hybridization and flow cytometry analysis of spontaneous abortions and mors in utero samples

Björn MentenKatrien SwertsBARBARA DELLE CHIAIESandra JanssensKaren BuysseJan PhilippéFranki Speleman

A1 Journal Article in BMC MEDICAL GENETICS

Downregulation of miR-449a is essential for the survival of EVI1 positive leukemic cells through modulation of NOTCH1 and BCL2

An De WeerPieter MestdaghKatleen De PreterJoni Van der MeulenPieter Van VlierbergheTom Van MaerkenNadine Van RoyMarta JeisonIsaac YanivBarbara Cauwelier et al.

EFFECT OF ZAP-70 ON MIRNA EXPRESSION PROFILE IN CHRONIC LYMPHOCYTIC LEUKEMIA

Valerie PedeJan PhilippéPieter MestdaghJo VandesompeleBruno Verhasselt

Guidelines for an integrated diagnostic approach of chronic lymphoproliferative diseases in the routine laboratory of haematology in Belgium

Jan PhilippéF NolletM BakkusP MeeusC DemanetN Schaaf-LafontaineS FrankeB ChatelainK VermeulenE Boone et al.

A1 Journal Article in ACTA CLINICA BELGICA

Hop bitter acids efficiently block inflammation independent of GRα, PPARα, or PPARγ

Marjan Van CleemputArne HeyerickClaude LibertKatrien SwertsJan PhilippéDenis De KeukeleireGuy HaegemanKarolien De Bosscher

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

MODULATION OF MIR-449A EXPRESSION DECREASES CELL VIABILITY, INCREASES APOPTOSIS AND INDUCES DIFFERENTIATION IN EVI1 DEREGULATED LEUKEMIA CELLS

An De WeerBruce PoppePieter MestdaghKatleen De PreterPieter Van VlierbergheNadine Van RoyM JeisonB CauwelierBruno VerhasseltJan Philippé et al.

Steroid effects on ZAP-70 and SYK in relation to apoptosis in poor prognosis chronic lymphocytic leukemia

Jerina BoelensSofie LustFEMKE VAN BOCKSTAELEMireille Van GeleAnn JanssensLara DeryckeBarbara VanhoeckeJan PhilippéMarc BrackeFritz Offner

A1 Journal Article in LEUKEMIA RESEARCH

Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia

Sofie LustBarbara VanhoeckeMireille Van GeleJerina BoelensHeleen Van MelckebekeMary KailehWim Vanden BergheGuy HaegemanJan PhilippéMarc Bracke et al.

A1 Journal Article in ANTICANCER RESEARCH

2008

A clinical-laboratory approach contributing to a rapid and reliable diagnosis of heparin-induced thrombocytopenia

Barbara DenysVeronique StoveJan PhilippéKatrien Devreese

A1 Journal Article in Thrombosis Research

Clinical cytometry in Europe, 2007 - Introduction

K JANOSM ARROZB BRANDOIA HEIJNENE KUIPER-KRAMERS PAPAJan PhilippéFW PREIJERSG ROTHEJW GRATAMA

Editorial material

Efficient gene transfer in CLL by mRNA electroporation

FEMKE VAN BOCKSTAELEValerie PedeEvelien NaessensStefanie Van CoppernolleV VAN TENDELOOBruno VerhasseltJan Philippé

A1 Journal Article in LEUKEMIA

EVII activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22)

An De WeerBruce PoppeBarbara CauwelierA CARLIERJ DIERICKBruno VerhasseltJan PhilippéNadine Van RoyFranki Speleman

A1 Journal Article in BMC CANCER

FDG uptake by the bone marrow in NSCLC patients is related to TGF-beta but not to VEGF or G-CSF serum levels

Christophe Van De WieleF VANDEVYVERC DEBRUYNEJan PhilippéJan Van Meerbeeck

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Minimal residual disease detection at day 35 in childhood acute lymphoblastic leukemia: Which technique(s) to use?

Katrien SwertsBarbara De MoerlooseB DENYSM BAKKUSBruno VerhasseltYves BenoitJan Philippé

Prognostic markers in chronic lymphocytic leukemia: A comprehensive review

FEMKE VAN BOCKSTAELEBruno VerhasseltJan Philippé

A1 Journal Article in Blood Reviews

Which technique(s) to use when studying minimal residual disease at day 35 in childhood acute lymphoblastic leukemia: a multicenter approach.

Barbara De MoerlooseKatrien SwertsM BAKKUSA UYTTEBROECKN BOECKXP VANDENBERGHEBruno VerhasseltA VAN DAMMEC DEMANETJan Philippé et al.

Which technique(s) to use when studying minimal residual disease at day 35 in childhood acute lymphoblastic leukemia: a multicenter approach.

Barbara De MoerlooseKatrien SwertsM BakkusA UyttebroeckN BoeckxP VandenbergheBruno VerhasseltA Van DammeC DemanetYves Benoit et al.

2007

B-CLL cells from lymph nodes express higher ZAP-70 levels than B-CLL cells from peripheral blood

Jerina BoelensJan PhilippéFritz Offner

A1 Journal Article in LEUKEMIA RESEARCH

Deguelin inhibits expression of I kappa B alpha protein and induces apoptosis of B-CLL cells in vitro

Ben GeeraertsBarbara VanhoeckeWim Vanden BergheJan PhilippéFritz OffnerDieter Deforce

A1 Journal Article in LEUKEMIA

DRAQ5: improved flow cytometric residual disease detection DNA content analysis and minimal in childhood malignancies

Katrien SwertsNadine Van RoyYves BenoitGenevieve LaureysJan Philippé

A1 Journal Article in CLINICA CHIMICA ACTA

Lipoprotein lipase mRNA expression in whole blood is a prognostic marker in B cell chronic lymphocytic leukemia

FEMKE VAN BOCKSTAELEValerie PedeA JANSSENSF CALLEWAERTFritz OffnerBruno VerhasseltJan Philippé

A1 Journal Article in CLINICAL CHEMISTRY

Methylprednisolone downregulates ZAP-70 expression in B-CLL cells in vitro

Jerina BoelensSofie LustAnn JanssensJan PhilippéFritz Offner

Prognostic significance of lipoprotein lipase expression in B-cell chronic lymphocytic leukemia

FEMKE VAN BOCKSTAELEValerie PedeAnn JanssensFilip CallewaertFritz OffnerBruno VerhasseltJan Philippé

Prognostic value of BCL2L13 expression in childhood B-cell acute lymphoblastic leukaemia

Katrien SwertsBarbara De MoerlooseCatharina DhoogeYves BenoitJan Philippé

Xanthohumol: a new potential proteasome inhibitor that activates the pro-apoptotic arm of the unfolded protein response in B-CLL cells

Sofie LustBarbara VanhoeckeMireille Van GeleJerina BoelensJan PhilippéPetra Vinckenmarc brackeMartine PoelmanFritz Offner

2006

ABO-mismatch adult living donor liver transplantation using antigen-specific immunoadsorption and quadruple immunosuppression without splenectomy

Roberto TroisiLucien NoensRoberto MontaltiSalvatore RicciardiJan PhilippéMarleen PraetPasquale ConoscitoreMichele CentraBernard de Hemptinne

A1 Journal Article in LIVER TRANSPLANTATION

EBV negative Richter's syndrome from a coexistent clone after salvage treatment with alemtuzumab in a CLL patient

A JANSSENSM BERTHP DE PAEPEBruno VerhasseltNadine Van RoyLucien NoensJan PhilippéFritz Offner

A1 Journal Article in AMERICAN JOURNAL OF HEMATOLOGY

In vitro screening for synergism of high-linear energy transfer Bi-213-radiotherapy with other therapeutic agents for the treatment of B-Cell chronic lymphocytic leukemia

Katia VandenbulckeHubert ThierensFilip De VosJan PhilippéFritz OffnerAnne JanssensC APOSTOLIDISA MORGENSTERNKlaus BacherVirginie de Gelder et al.

A1 Journal Article in CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Kolmogorov-Smirnov statistical test for analysis of ZAP-70 expression in B-CLL, compared with quantitative PCR and IgVH mutation status

FEMKE VAN BOCKSTAELEAnn JanssensAnne PietteFilip CallewaertValerie PedeFritz OffnerBruno VerhasseltJan Philippé

A1 Journal Article in CYTOMETRY PART B-CLINICAL CYTOMETRY

Maximum oxygen uptake at peak exercise in elderly patients with coronary artery disease and preserved left ventricular function: The role of inflammation on top of tissue Doppler-derived systolic and diastolic function

Nico Van de VeireOlivier De WinterJan PhilippéMarc De BuyzereDirk BernardMichel LangloisThierry GillebertJohan De Sutter

A1 Journal Article in AMERICAN HEART JOURNAL

Neurohumoral and inflammatory activation in patients with coronary artery disease treated with statins

Nico Van de VeireJan PhilippéOlivier De WinterMichel LangloisD BERNARDJohan De Sutter

Editorial material

Opsporing en klinisch belang van minimale residuele ziekte bij neuroblastoompatiënten

Katrien SwertsYves BenoitGenevieve LaureysJan Philippé

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Potential application of ELAVL4 real-time quantitative reverse transcription-PCR for detection of disseminated neuroblastoma cells

Katrien SwertsBarbara De MoerlooseCatharina DhoogeJo VandesompeleC HOYOUXK BEISKEYves BenoitGenevieve LaureysJan Philippé

A1 Journal Article in CLINICAL CHEMISTRY

Prognostic significance of multidrug resistance-related proteins in childhood acute lymphoblastic leukaemia

Katrien SwertsBarbara De MoerlooseCatharina DhoogeGenevieve LaureysYves BenoitJan Philippé

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma

Tom Van MaerkenFranki SpelemanJ VERMEULENIrina LambertzSarah De ClercqEls De SmetNurten YigitV COPPENSJan PhilippéAnne De Paepe et al.

A1 Journal Article in CANCER RESEARCH

VE/Vco(2) slope and oxygen uptake efficiency slope in patients with coronary artery disease and intermediate peakVo(2)

Nico Van de VeireChristophe Van LaethemJan PhilippéOlivier De WinterGui De BackerM VANDERHEYDENJohan De Sutter

A1 Journal Article in EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION

2005

Baseline nucleophosmin status in mutated(M) versus unmutated (U) immunoglobulin B-CLL is a nuclear reflection of different signal transduction physiology

JENS BOELENSW. Van den BergheGuy HaegemanAnne JanssensJan PhilippéFritz Offner

Baseline nucleophosmin status in mutated(M) versus unmutated(U) immunoglobulin B-CLL is a nuclear reflection of different signal transduction physiology

Jerina BoelensWim Vanden BergheGuy HaegemanAnne JanssensJan PhilippéFritz Offner

Correlation of ZAP-70 analysed by RT-PCR with ZAP-70 determined by flow cytometry and with IgVH mutational status in B-CLL

Jan PhilippéFEMKE VAN BOCKSTAELEFilip CallewaertA JANSSENSFritz OffnerBruno Verhasselt

Neurohumoral activation: the missing link in statin treated patients with persistent inflammatory activation?

Nico Van de VeireJohan De SutterMarc De BuyzereJan PhilippéDirk BernardMichel LangloisAK ASCOOPThierry Gillebert

Novel cryptic chromosomal rearrangements in childhood acute lymphoblastic leukemia detected by multiple color fluorescent in situ hybridization

Bruce PoppeBarbara CauwelierH VAN LIMBERGENNurten YigitJan PhilippéBruno VerhasseltAnne De PaepeYves BenoitFranki Speleman

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

Prognostische factoren bij B-CLL

Jan PhilippéANN JANSSENSFritz Offner

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

VH-gene usage is of prognostic value in B-cell chronic lymphocytic leukemia

FEMKE VAN BOCKSTAELEKaatje SmitsFritz OffnerAnne JanssensJan PhilippéBruno Verhasselt

Xanthohumol induces apoptosis in B-CLL mediated by caspase 9 following downregulation of bcL-xL and mcl-1

Barbara VanhoeckeSofie LustAnne JanssensJan Philippémarc brackeFritz Offner

Xanthohumol kills B-chronic lymphocytic leukemia cells by an apoptotic mechanism

Sofie LustBarbara VanhoeckeAnne JanssensJan Philippémarc brackeFritz Offner

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

2004

Clinical chemistry in Rwanda

Joris DelangheJan Philippé

Editorial material

Comparison of five different citrated tubes and their in vitro effects on platelet activation

Jan PhilippéErik De LogiGaston Baele

A1 Journal Article in CLINICAL CHEMISTRY

Comparison of two functional flow cytometric assays to assess P-gp activity in acute leukemia

Katrien SwertsBarbara De MoerlooseCatharina DhoogeLucien NoensGenevieve LaureysYves BenoitJan Philippé

A1 Journal Article in LEUKEMIA & LYMPHOMA

Correlation of ZAP-70 analysed by flow cytometry with IgVH mutational status in B-CLL

Jan PhilippéB LEUSAnne PietteFEMKE VAN BOCKSTAELEANN JANSSENSFritz Offner

CXCL-12 induces prolonged erk-phosphorylation in Zap-70 positive B-CLL

Sofie LustJerina BoelensANN JANSSENSJan Philippémarc brackeFritz Offner

Detection of residual neuroblastoma cells in bone marrow: Comparison of flow cytometry with immunocytochemistry

K SWERTSBarbara De MoerlooseCatharina DhoogeB BRICHARDYves BenoitGenevieve LaureysJan Philippé

A1 Journal Article in CYTOMETRY PART B-CLINICAL CYTOMETRY

Four-color flow cytometric detection of residual neuroblastoma cells

Jan PhilippéKatrien SwertsBarbara De MoerlooseCatharina DhoogeYves BenoitGenevieve Laureys

Importance of receptor density in alpha radioimmunotherapy in B cell malignancies: an in-vitro study

Katia VandenbulckeHubert ThierensFritz OffnerAnne JanssensVirginie de GelderKlaus BacherJan PhilippéFilip De VosRudi DierckxC APOSTOLIDIS et al.

A1 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

Targeted alpha radiation and gamma rays induce distinct and mutation status specific transcriptional responses in human leukemic lymphocytes

S MARTINR KRONENWETTK VANDENBUICKEFritz OffnerS KLISZEWSKIC APOSTOLIDISA MORGENSTERNU STEIDLS RASCHKEF NEUMANN et al.

The restricted V-H-gene usage is of prognostic value in B-cell chronic lymphocytic leukemia

Jan PhilippéFEMKE VAN BOCKSTAELEKaatje SmitsFritz OffnerBruno VerhasseltANN JANSSENS

The use of IL-2 cultures to measure chromosomal radiosensitivity in breast cancer patients

Ans BaeyensKatia VandenbulckeJan PhilippéHubert ThierensLeo De RidderAnne Vral

A1 Journal Article in MUTAGENESIS

VH-gene usage is of prognostic value in CLL

Jan PhilippéANN JANSSENSKaatje SmitsILSE MOLLETFritz Offner

2003

Alpha-immunotherapy compared to external gamma irradiation, cold antibody and chemotherapy in B-CLL in vitro: Correlation with clinical chemotherapy sensitivity

K VANDENBULCKEFritz OffnerFilip De VosA JANSSENST NIKULAC APOSTOLIDESR MOLINETW JANSSENSHubert ThierensRudi Dierckx et al.

Cold and alpha-conjugated anti-CD20 induce different in vitro apoptosis reponses in B-chronic lymphocytic leukaemia (B-CLL)and splenic lymphoma with villous lymphocytes (SLVL)

K VANDENBULCKEFritz OffnerGuido SlegersFilip De VosVirginie de GelderA WILLEMSS MARTINR MOLINETC APOSTOLIDISTK NIKULA et al.

Cytotoxicity of gamma versus alpha radiation in lymphoid cell lines with defects in the TNF receptor family mediated and NF-kappa B related apoptotic and anti-apoptotic pathways

KJ VANDENBULCKEK VANDENBULCKERudi BeyaertC APOSTOLIDEST NIKULAW JANSSENSANN JANSSENSVirginie de GelderAnnick WillemsGuido Slegers et al.

In vitro evaluation of Bi-213-rituximab versus external gamma irradiation for the treatment of B-CLL patients: relative biological efficacy with respect to apoptosis induction and chromosomal damage

Katia VandenbulckeFILIP DE VOSFritz OffnerJan PhilippéC APOSTOLIDISR MOLINETTK NIKULAKlaus BacherV DE GELDERAnne Vral et al.

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

In vitro evaluation of Bi-213-rituximab versus external gamma irradiation for the treatment of B-CLL patients: Relative biological efficacy with respect to apoptosis induction and chromosomal damage by the micronucleus assay

K VANDENBULCKEFilip De VosFritz OffnerJan PhilippéC APOSTOLIDISR MOLINETTK NIKULAKlaus BacherVirginie de GelderAnne Vral et al.

Molecular mechanisms of alpha-particles-induced cytotoxicity in human leukemic cells as revealed by gene expression profiling

S MARTINR KRONENWETTK VANDENBULCKEFritz OffnerS KLISZEWSKIC APOSTOLIDISR CARLOSW JANSSENSM LEROYT NIKULA et al.

The combined analysis of P-glycoprotein expression and activity predicts outcome in childhood acute lymphoblastic leukemia

Barbara De MoerlooseKatrien SwertsYves BenoitGenevieve LaureysTom LoeysJan PhilippéCatharina Dhooge

A1 Journal Article in PEDIATRIC HEMATOLOGY AND ONCOLOGY

The quantification of MDR1 transcripts by real-time RT-PCR does not predict drug resistance in childhood acute lymphoblastic leukemia

Katrien SwertsBarbara De MoerlooseB LEUSCatharina DhoogeGenevieve LaureysBruno VerhasseltYves BenoitJan Philippé

2002

Alpha-immunotherapy compared to gamma-radiation, cold antibody, and chemotherapy in B-CLL in vitro: Correlation with clinical chemosensitivity

Fritz OffnerKL VANDENBULCKEF DEVOSANN JANSSENSJan PhilippéGuido SlegersHubert ThierensT NIKULAC APOSTOLIDESW JANSSENS et al.

Annexin V expression in apoptotic peripheral blood lymphocytes: an electron microscopic evaluation

Maria CornelissenJan PhilippéS De SitterLeo De Ridder

A1 Journal Article in APOPTOSIS

Evolution of hepatitis C virus-specific T cell responses and cytokine production in chronic hepatitis C patients treated with high doses of interferon-alpha.

CA ESQUIVELA ELEWAUTJan PhilippéAE ELEWAUTIsabelle DesombereG MAERTENSGeert Leroux-Roels

A1 Journal Article in REVISTA DE INVESTIGACION CLINICA

Expression of the multidrug transporter P-glycoprotein is highly correlated with clinical outcome in childhood acute lymphoblastic leukemia: Results of a long-term prospective study.

Catharina DhoogeBarbara De MoerlooseGenevieve LaureysA FERSTERDirk De BacquerJan PhilippéJuliaan LeroyYves Benoit

A1 Journal Article in LEUKEMIA & LYMPHOMA

Structure and function of the N-cadherin/catenin complex in retinoblastoma.

Elisabeth Van AkenP PAPELEUP DE POTTERErik BruyneelJan PhilippéS SEREGARDA KVANTAJean DelaeyMarcus Mareel

A1 Journal Article in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

2001

Alkyl-lysophospholipid 1-O-octadecyl-2-O-methyl-glycerophosphocholine induces invasion through epislalin-mediated neutralization of E-cadherin in human mammary MCF-7 cells in vitro.

Wim SteelantJL GOEMANJan PhilippéL OOMENJ HILKENSMA KRZEWINSKI-RECCHIG HUETJohan Van der EyckenP DELANNOYErik Bruyneel et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Combined evaluation of P-glycoprotein expression and activity contributes to the identification of children at risk for leukaemic relapse

Barbara De MoerlooseKatrien SwertsCatharina DhoogeS STEYAERTYves BenoitGenevieve LaureysJan Philippé

Comparison of in vitro apoptosis induction by alpha-irradiation versus gamma-irradiation in B-CLL

Fritz OffnerFilip De VosK VANDENBULCKEANN JANSSENSR MOLINETC APOSTOLIDISW JANSSENST NIKULAChristophe LahorteB BRANS et al.

Synthesis and in vitro evaluation of I-123-labelled human recombinant annexin V.

C LAHORTEG SLEGERSJan PhilippéC VAN DE WIELERudi Dierckx

A1 Journal Article in BIOMOLECULAR ENGINEERING

2000

In vitro apoptosegevoeligheid van B-cel chronische lymfatische leukemie-lymfocyten en hun moleculair-biologische kenmerken

G Van CausbroeckA JanssensW Vanden BergheHubert ThierensG HaegemanJan Philippé

A4 Journal Article in TIJDSCHRIFT VAN DE BELGISCHE VERENIGING VAN LABORATORIUM-TECHNOLOGEN = REVUE DE L'ASSOCIATION BELGE DES TECHNOLOGUES DE LABORATOIRE

Multiple sclerosis: een immunologische benadering

J DebruyneJan Philippé

A4 Journal Article in NEURON (NEDERLANDSE ED.)

Repetitive analyses of P-glycoprotein in chronic myeloid leukaemia

Barbara De MoerlooseA MuylaertF GemmelAnne JanssensBruce PoppeCatharina DhoogeWerner Van HoveJan Philippé

A1 Journal Article in ACTA CLINICA BELGICA

Synthesis and in vitro stability of 123I-labelled annexin V: a potential agent for SPECT imaging of apoptotic cells.

C LAHORTEFilip DumontG SLEGERSC VAN DE WIELERudi DierckxJan Philippé

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

1999

Apoptosis induced by γ irradiation in peripheral blood mononuclear cells is not mediated by cytochrome-c release and only partially involves caspase-3-like proteases

Henk LouagiePeter SchotteAnne VralMaria CornelissenHubert ThierensRudi BeyaertLeo De RidderJan Philippé

A1 Journal Article in CELL BIOLOGY INTERNATIONAL

Belgian consensus recommendations for flow cytometric immunophenotyping

DR Van BockstaeleV DeneysJan PhilippéM BernierL KestensB ChatelainM De WaeleC Demanet

A1 Journal Article in ACTA CLINICA BELGICA

Changes in peripheral blood lymphocyte subsets in patients undergoing radiotherapy.

Henk LouagieMarc Van EijkerenJan PhilippéHubert ThierensLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Cytokine removal during continuous hemofiltration in septic patients.

An De VrieseFrancis ColardynJan PhilippéRaymond VanholderJohan De SutterNorbert Lameire

A1 Journal Article in JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Discordance of P-glycoprotein expression and function in acute leukemia.

B DE MOERLOOSECatharina DhoogeJan Philippé

A1 Journal Article in DRUG RESISTANCE IN LEUKEMIA AND LYMPHOMA III

Discrepant flow cytometric expression and function of P-glycoprotein in neuroblastic tumors

Barbara De MoerlooseCatharina DhoogeGenevieve LaureysYves BenoitM DEMARCHEC DEVALCKD PLANTAZJuliaan LeroyJan Philippé

A1 Journal Article in CYTOMETRY

P-glycoprotein is an independent prognostic factor predicting relapse in childhood acute lymphoblastic leukaemia : results of a 6-year prospective study

Catharina DhoogeBarbara De MoerlooseGenevieve LaureysJozef KintA FersterDirk De BacquerJan PhilippéYves Benoit

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Synthesis and apoptogenic activity of fluorinated ceramide and dihydroceramide analogues

Steven De JongheIlse Van OvermeireJ. GunstAndré De BruynC. HendrixSerge Van CalenberghR. BussonDenis De KeukeleireJan PhilippéPiet Herdewijn

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Technetium-99m sestamibi imaging in paediatric neuroblastoma and ganglioneuroma and its relation to P-glycoprotein.

Barbara De MoerlooseC VAN DE WIELECatharina DhoogeJan PhilippéFranki SpelemanYves BenoitGenevieve LaureysRudi Dierckx

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE

The αE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells

Stefan VermeulenFriedel NolletE TEUGELSKM VENNEKENSFransiska MalfaitJan PhilippéFranki SpelemanMarc BrackeFrans Van RoyMarcus Mareel

A1 Journal Article in ONCOGENE

1998

Apoptosis induced by fast neutrons versus Co-60 gamma-rays in human peripheral blood lymphocytes

Anne VralMaria CornelissenHubert ThierensHenk LouagieJan PhilippéKarel StrijckmansLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Erroneous monocyte and neutrophil counts with the Sysmex NE-1500 in patients recovering from bone marrow aplasia.

J VAN ACKERP WILMESJan Philippé

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Flow cytometric scoring of apoptosis compared to electron microscopy in γ irradiated lymphocytes

Henk LouagieMaria CornelissenJan PhilippéAnne VralHubert ThierensLeo De Ridder

A1 Journal Article in CELL BIOLOGY INTERNATIONAL

Inductie van micronuclei apoptose in natural killer cellen in vergelijking met T lymfocyten na γ-bestraling

L LouagieJan PhilippéAnne VralMaria CornelissenHubert ThierensLeo De Ridder

A4 Journal Article in TIJDSCHRIFT VAN DE BELGISCHE VERENIGING VAN LABORATORIUM-TECHNOLOGEN = REVUE DE L'ASSOCIATION BELGE DES TECHNOLOGUES DE LABORATOIRE

Induction of micronuclei and apoptosis in natural killer cells compared to T lymphocytes after gamma-irradiation.

H LOUAGIEJan PhilippéAnne VralMaria CornelissenHubert ThierensI DE RIDDER

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Micronucleus frequencies in cytokinesis-blocked human B lymphocytes after low dose gamma-irradiation.

Anne VralHenk LouagieHubert ThierensJan PhilippéMaria CornelissenLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Relapse markers in multiple sclerosis: are in vitro cytokine production changes reflected by circulatory T-cell phenotype alterations?

Jan DebruyneJan PhilippéJacques De ReuckA WILLEMSGeert Leroux-Roels

A1 Journal Article in MULTIPLE SCLEROSIS

1997

Anti-invasive activity of alkaloids and polyphenolics in vitro.

VS PARMARmarc brackeJan PhilippéJ WENGELSC JAINCE OLSENKS BISHTNK SHARMAA COURTENSSK SHARMA et al.

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Distribution of lymphocyte subsets in bone marrow and peripheral blood is associated with haptoglobin type - Binding of haptoglobin to the B-cell lectin CD22.

Michel LangloisJoris DelangheJan PhilippéJin OuyangD BERNARDMarc De BuyzereG VANNOOTENGeert Leroux-Roels

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY

Expression of the MDR1 gene product P-glycoprotein in childhood neuroblastoma

Catharina DhoogeBarbara De MoerlooseYves BenoitNadine Van RoyJan PhilippéGenevieve Laureys

A1 Journal Article in CANCER

Flow cytometry as a quantitative and sensitive method to evaluate low dose radiation induced apoptosis in vitro in human peripheral blood lymphocytes

Koen HertveldtJan PhilippéHubert ThierensMaria CornelissenAnne VralLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Functional downregulation of the E-cadherin/catenin complex leads to loss of contact inhibition of motility and of mitochondrial activity, but not of growth in confluent epithelial cell cultures

Marc BrackeHerman DepypereC LabitVeerle Van MarckK VennekensSJ VermeulenI MaelfaitJan PhilippéRudolphe SerreynMarcus Mareel

A1 Journal Article in EUROPEAN JOURNAL OF CELL BIOLOGY

Mutation of alpha-catenin results in invasiveness of human HCT-8 colon cancer cells.

SJ VERMEULENF NOLLETE TEUGELSJan PhilippéFranki SpelemanFrans Van Roymarc brackeMarcus Mareel

A1 Journal Article in ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

Quantification of apoptosis in lymphocyte subsets and effect of apoptosis on apparent expression of membrane antigens

Jan PhilippéHenk LouagieHubert ThierensAnne VralMaria CornelissenLeo De Ridder

A1 Journal Article in CYTOMETRY

Relationschip of decreased chemotaxis of technetium-99-m-HMPAO-labeled lymphocytes to apoptosis

Christophe Van De WieleJan PhilippéJP VAN HAELSTJozef Van DammeHubert ThierensGeert Leroux-RoelsRudi Dierckx

A2 Journal Article in Journal Nuclear Medicine, nr. 38, pp. 1417-1421, 2 figg

Relationship of decreased chemotaxis of technetium-99m-HMPAO-labeled lymphocytes to apoptosis

C Van de WieleJan PhilippéJP Van HaelstJozef Van DammeHubert ThierensGeert Leroux-RoelsRudi Dierckx

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

1996

Immunocytochemical and flow cytometric analysis of P-glycoprotein in childhood ALL

Barbara De MoerlooseJan PhilippéCatharina Dhooge

In vitro TNF-alpha, IL-2 and IFN-gamma production as markers of relapses in multiple sclerosis.

Jan PhilippéJan DebruyneGeert Leroux-RoelsA WILLEMSJacques De Reuck

A1 Journal Article in CLINICAL NEUROLOGY AND NEUROSURGERY

Interference of soluble TNF-alpha receptors in immunological detection of tumor necrosis factor-alpha.

E MOREAUJan PhilippéS COUVENTGeert Leroux-Roels

A1 Journal Article in CLINICAL CHEMISTRY

Lymphoproliferative responses to hepatitis C virus core, E1, E2, and NS3 in patients with chronic hepatitis C infection treated with interferon alfa.

Geert Leroux-RoelsCA ESQUIVELR DELEYSL STUYVERAndré ElewautJan PhilippéIsabelle DesombereJoseph ParadijsG MAERTENS

A1 Journal Article in HEPATOLOGY

Prognostic markers in septic shock

Jan PhilippéFritz OffnerGaston BaeleGeert Leroux-Roels

1995

CARBAMAZEPINE HYPERSENSITIVITY SYNDROME - REPORT OF 4 CASES AND REVIEW OF THE LITERATURE.

ASP DEVRIESEJan PhilippéDM VANRENTERGHEMCA DECUYPERPHF HINDRYCKXEGJ MATTHYSA LOUAGIE

A1 Journal Article in MEDICINE

Cytokines in vaccine research

Geert Leroux-RoelsIsabelle DesombereJ PARADIJSJ VINGERHOETSJan Philippé

A4 Journal Article in Cytokine News - Medgenix Diagnostics

FLOW-CYTOMETRY TO OVERCOME INTERFERENCES IN IMPEDANCE-BASED LEUKOCYTE COUNTING.

H LOUAGIEE MOREAUJan PhilippéGeert Leroux-Roels

A1 Journal Article in CLINICAL CHEMISTRY

1994

Increased platelet response to ADP-stimulation in vitro in peripheral arterial occlusive disease after treadmill exercise

S VERSCHUERENJan PhilippéDaniel DuprezMarc De BuyzereGeert Leroux-Roels

PERFORMANCE OF THE COULTER STKS AND THE SYSMEX-NE-1500 IN A PEDIATRIC POPULATION.

E MOREAUJan PhilippéJozef KintYves BenoitGeert Leroux-Roels

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY

1993

Changes in platelet number and function in peripheral arterial occlusive disease

Jan PhilippéS VanderschuerenMarc De BuyzereDaniel DuprezGaston BaeleGeert Leroux-Roels

Coagulation system activation and increase of D-dimers levels in peripheral arterial occlusive disease

Marc De BuyzereJan PhilippéDaniel DuprezGaston BaeleDenis Clement

A1 Journal Article in AMERICAN JOURNAL OF HEMATOLOGY

De klinische toepassingen van flowcytometrie.

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Flow cytometric detection of platelet response to ADP in peripheral arterial occlusive disease after treadmill exercise

S VanderschuerenJan PhilippéMarc De BuyzereDaniel DuprezGeert Leroux-Roels

Flow cytometric detection of platelet response to ADP in peripheral arterial occlusive disease after treadmill exercise

S VanderschuerenJan PhilippéMarc De BuyzereDaniel DuprezDenis Clement

Increased plasma-levels of molecular markers of coagulation activation and secondary fibrinolysis in peripheral arterial occlusive disease

Gaston BaeleMarc De BuyzereJan PhilippéDaniel DuprezDenis ClementGeert Leroux-Roels

Simple flow cytometric detection of platelet activation

S VANDERSCHUERENJan PhilippéMarc De BuyzereDaniel DuprezGeert Leroux-Roels

A2 Journal Article in EUT. J. Clin. Chem. Clin. Biochem., 31, nr. 4, A8

1992

Bloedstolling en oplossen van bloedstolsels bij patiënten met zeer ernstige infectie of sepsis

A2 Journal Article in TIJDSCHRIFT VOOR CARDIOLOGIE

GRANULOCYTE ELASTASE, TUMOR-NECROSIS-FACTOR-ALPHA AND UROKINASE LEVELS AS PROGNOSTIC MARKERS IN SEVERE INFECTION.

Jan PhilippéG DOOIJEWAARDFritz OffnerP TURIONGaston BaeleGeert Leroux-Roels

A1 Journal Article in THROMBOSIS AND HAEMOSTASIS

Plasma urokinase levels in cardiovascular diseases

Jan PhilippéMarc De BuyzereDaniel DuprezA WEYNEGeert Leroux-RoelsGaston Baele

A2 Journal Article in THROMBOSIS RESEARCH

Prothrombin activation fragment 1+2, thrombin-antithrombin III complex and D-dimer determinations in peripheral arterial occlusive disease - influence of treadmill exercise.

Gaston BaeleDaniel DuprezMarc De BuyzereJan PhilippéDenis ClementGeert Leroux-Roels

A2 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

STIMULATION OF ERYTHROPOIETIN PRODUCTION AFTER CONTROLLED BLOOD-LOSS.

Jan PhilippéGeert Leroux-RoelsMarc De BuyzereA WEYNE

A1 Journal Article in EUROPEAN JOURNAL OF HAEMATOLOGY

The relationship between TNF-a and liver failure

Jan PhilippéFritz OffnerGeert Leroux-Roels

A2 Journal Article in Eur. Cytokine Netw., 3, p. 253

1991

Evaluation of the automated haematology analyser Sysmex NE-8000

Katrien DevreeseErik De LogiChristiane FrancartB HeyndrickxJan PhilippéGeert Leroux-Roels

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY

Fibrinolysis and coagulation in patients with infectious disease and sepsis

Jan PhilippéFritz OffnerPJ De ClerckGeert Leroux-RoelsDirk VogelaersGaston BaeleD Collen

A1 Journal Article in THROMBOSIS AND HAEMOSTASIS

Fibrinolytic and coagulant profile in severe infection and sepsis

Jan PhilippéGeert Leroux-Roels

Quality control in antimicrobial disk susceptibility testing: a Belgian multicenter study

S LauwersJan PhilippéA Van ZeebroeckD PierardMP DerdeL Kaufman

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Serum TNF levels in patients with infectious disease and septic shock

Fritz OffnerJan PhilippéDirk VogelaersGaston BaeleFrancis ColardynM BaudrihayeAlex VermeulenGeert Leroux-Roels

Bookchapter in The year book of surgery 1991

1990

In-vitro production of cytokines in blood

Geert Leroux-RoelsJan PhilippéFritz OffnerAlex Vermeulen

A1 Journal Article in LANCET

Serum tumor necrosis factor levels in patients with infectious disease and septic shock

Fritz OffnerJan PhilippéDirk VogelaersFrancis ColardynGaston BaeleM BaudrihayeAlex VermeulenGeert Leroux-Roels

A1 Journal Article in JOURNAL OF LABORATORY AND CLINICAL MEDICINE

1988

Endotoxin: detection and clinical significance

Jan PhilippéMarc De Buyzere

A1 Journal Article in ACTA CLINICA BELGICA

Influence of blood-collecting systems on concentrations of tumor necrosis factor in serum and plasma

Geert Leroux-RoelsFritz OffnerJan PhilippéAlex Vermeulen

A1 Journal Article in CLINICAL CHEMISTRY

Onderzoek naar een aantal prognostische markers bij patiënten met zeer ernstige infectie of sepsis. 8e Amstol Symposium, Amsterdam, 25/9/1992, werkboek p. 3.4.

Jan PhilippéG DOOUEWAARDFritz OffnerP TURIONGaston BaeleGeert Leroux-Roels