Research Explorer

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Researcher

Jan Jacobs

Awards & Distinctions

27 Results

2014

1,2,3,4,8,9,10,11-Octahydrobenzo[j]phenanthridine-7,12-diones as new leads against Mycobacterium tuberculosis

Davie CappoenPieter ClaesJan JacobsRoel AnthonissenVanessa MathysLuc VerschaeveKris HuygenNorbert De Kimpe

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

2013

Palladium(II)-catalyzed synthesis of 2H,3'H‑spiro[benzofuran-3,2'-naphthoquinones]

Pieter ClaesJan JacobsBart KesteleynTuyen Nguyen VanNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Synthesis and antimycobacterial activity of analogues of the bioactive natural products sampangine and cleistopholine

Pieter ClaesDavie CappoenBlaise Mbala-MavingaJan JacobsBirgit MertensVanessa MathysLuc VerschaeveKris HuygenNorbert De Kimpe

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2012

Diastereoselective Aldol reaction of Zincated 3-Chloro-3-methyl-1-azaallylic anions as key step in the synthesis of 1,2,3,4-Tetrasubstituted 3-Chloroazetidines

Sven MangelinckxBart De SterckFilip ColpaertSaron CatakJan JacobsStijn RooryckMichel WaroquierVeronique Van SpeybroeckNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Straightforward palladium-mediated synthesis and biological evaluation of benzo[j]phenanthridine-7,12-diones as anti-tuberculosis agents

Davie CappoenJan JacobsTuyen Nguyen VanSven ClaessensGaston DielsRoel AnthonissenThorbjorg EinarsdottirMaryse FauvilleLuc VerschaeveKris Huygen et al.

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2011

A survey of synthetic routes towards 2-azaanthraquinones

Jan JacobsKourosch Abbaspour TehraniNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Investigation towards an efficient synthesis of benzo[g]isoquinoline-1,5,10(2H)-triones

Blaise Mbala-MavingaJan JacobsPieter ClaesVrima MudogoNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Pyridinium ylids in heterocyclic synthesis

Jan JacobsEva Van HendeSven ClaessensNorbert De Kimpe

A1 Journal Article in CURRENT ORGANIC CHEMISTRY

Synthesis of 1-substituted 1,2,3,4-tetrahydrobenz[g]isoquinoline-5,10-diones

Ekaterina ShinkevichJurgen DeblanderSandra MatthijsJan JacobsNorbert De KimpeKourosch Abbaspour Tehrani

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

2010

First enantioselective synthesis of isagarin, a natural product isolated from Pentas longiflora Oliv

Jan JacobsSven ClaessensEva De MolSamir El HadyCristina MinguillonMercedes AlvarezNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Short synthesis of functionalized pentalongin derivatives using pyridinium ylid chemistry

Pieter ClaesJan JacobsSven ClaessensNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

2009

1,4-Dehydrochlorination of 1-(1-haloalkyl)-3,4-dihydroisoquinolines as a convenient route to functionalized isoquinolines

Jan JacobsTuyen Nguyen VanChristian StevensPeter MarkussePaul De CoomanLeendert MaatNorbert De Kimpe

A1 Journal Article in TETRAHEDRON LETTERS

A new synthesis of benzo[f]isoindole-4,9-diones by radical alkylation and bromomethylation of 1,4-naphthoquinones

Jurgen DeblanderSam Van AekenJan JacobsNorbert De KimpeKourosch Abbaspour Tehrani

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Insight into the solvation and isomerization of 3-halo-1-azaallylic anions from ab initio metadynamics calculations and NMR experiments

Reinout DeclerckBart De SterckToon VerstraelenGuido VerniestSven MangelinckxJan JacobsNorbert De KimpeMichel WaroquierVeronique Van Speybroeck

A1 Journal Article in Chemistry - A European Journal

New and highly efficient synthesis of 3-substituted 1-hydroxybenz[g]isoquinoline-5,10-diones

Jan JacobsSven ClaessensBlaise Mavinga MbalaKris HuygenNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

New synthesis of 1-[(3,4-dimethoxyphenyl)methoxymethyl]-6,7-dimethoxyisoquinoline (setigerine), a naturally occurring alkaloid, and some derivatives of papaverine

Jan JacobsTuyen Nguyen VanPeter MarkusseChristian StevensLeendert MaatNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Toward establishing structure-activity relationships for oxygenated coumarins as differentiation inducers of promonocytic leukemic cells

Maria E RivieroDominick MaesRamiro VasquezMonica VermeulenSven MangelinckxJan JacobsSilvia DebenedettiCarina ShayoNorbert De KimpeCarlos Davio

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

2008

First straightforward synthesis of 1-hydroxy-3,4-dihydro-1H-benz[g]isochromene-5,10-dione and structure revision of a bioactive benz[g]isochromene-5,10-dione from Psychotria camponutans

Jan JacobsSven ClaessensNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

First straightforward synthesis of 2,4-disubstituted benz[g]isoquinoline-3,5,10(2H)-triones, 1,2,3,5-substituted naphtho[3,2,1-de]isoquinoline-4,7-diones, and 6-substituted benzo[h]pyrido[3,4,5-kl]-1,2,3,4-tetrahydroacridine-5,8-diones

Jan JacobsB KESTEEYNNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Straightforward palladium-mediated synthesis of N-substituted 1,2-dihydrobenz[g]isoquinoline-5,10-diones

Jan JacobsBM MBALAB KESTELEYNG DIELSNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Synthesis of N-substituted 1,2,3,4-tetrahydrobenz[g]isoquinoline-5,10-diones

Jan JacobsJ DEBLANDERB KESTELEYNKA TEHRANINorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Synthesis of N-substituted 1,2-dihydrobenz[g]isoquinoline-5,10-diones

Jan JacobsB KESTELEYNNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Synthesis of benzo[f]isoindole-4,9-diones

Sven ClaessensJan JacobsS VAN AEKENKA TEHRANINorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

2007

A survey of synthetic routes towards the pyranonaphthoquinone antibiotic pentalongin and syntheses of the corresponding nitrogen derivatives

Sven ClaessensGuido VerniestJan JacobsEva Van HendePascal HabonimanaTN VANL VAN PUYVELDENorbert De Kimpe

A1 Journal Article in SYNLETT

New synthesis of N-substituted benz[g]isoquinoline-3,5,10(2H)-triones

Jan JacobsSven ClaessensB KESTELEYNK HUYGENNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Straightforward synthesis of alkynyl imines via 1,2-elimination of alpha,alpha-dichloroketimines

Sven MangelinckxStijn RooryckJan JacobsNorbert De Kimpe

A1 Journal Article in TETRAHEDRON LETTERS

Synthesis of 2-Aza-1-cyano-4-hydroxyanthraquinones

Sven ClaessensJan JacobsNorbert De Kimpe

A1 Journal Article in SYNLETT