Research Explorer

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Researcher

Jan De Waele

Publications & Research Data

Awards & Distinctions

495 Results

2026

Beyond binary AKI classification : development and external validation of a distributional model predicting serum creatinine and urine output trajectories in ICU patients

Jef JonkersAnahita RouzéJarne VerhaegheWim Van BiesenJan De WaeleLuc DuchateauGlenn Van WallendaelEric HosteSofie Van Hoecke

A1 Journal Article in CRITICAL CARE

Body mass index and mortality : the 'Obesity Paradox' in critically ill patients with intra-abdominal infection or sepsis : an international cohort study

Fien DonckelsMassimo AntonelliKostoula ArvanitiBen Creagh-BrownElena ConoscentiDylan W de LangeGennaro De PascaleJan De WaeleMieke DeschepperYalim Dikmen et al.

A1 Journal Article in INTENSIVE AND CRITICAL CARE NURSING

Current standard of care for septic shock

Anthony DelaneyMarcio Borges-SaMichelle S. ChewJan De WaeleJacob DyeAshish K. KhannaOlfa HamzaouiNaomi HammondGlenn HernandezMargaret Herridge et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Exploiting the natural power of phage lysins as novel enzyme-based antibiotics to treat polymicrobial Gram-negative infections

Gilles VandermarliereGuy HermansDennis GrimonYves BriersRoberto VázquezVeronique StoveJan De Waele

Paracetamol switch op intensieve zorg : een haalbare stap naar duurzame zorg

Jolien LanguiLore SchoonbaertJan De WaeleBarbara Claus

Parenting, pregnancy and work-family balance in intensive care medicine: an ESICM survey and a call for action

Gaetano ScaramuzzoJekaterina Jagodzinska-PeškovaGiacomo GrasselliElena ConoscentiJan De Waele[missing] on behalf of the ESICM Work-Family Balance, Parenting and Pregnancy group

A1 Journal Article in INTENSIVE CARE MEDICINE

Understanding and engineering phage lysin specificity to treat polymicrobial Gram-negative infections

Gilles VandermarliereGuy HermansDennis GrimonRoberto VázquezVeronique StoveJan De WaeleYves Briers

2025

A consensus of European experts on the definition of ventilator-associated pneumonia recurrences obtained by the Delphi method : the RECUVAP study

Antoine GailletCharles-Edouard LuytJean-Francois TimsitKarim AsehnouneFrancois BarbierMatteo BassettiLila BouadmaAdrien BougleJean ChastreAndrew Conway Morris et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

A pooled pharmacokinetic analysis for piperacillin/tazobactam across different patient populations : from premature infants to the elderly

Daming KongJason A. RobertsJeffrey LipmanFabio Silvio TacconeMichael Cohen-WolkowiezFekade B. SimeDanny TsaiPieter De CockSutep JaruratanasirikulSofie A. M. Dhaese et al.

A1 Journal Article in CLINICAL PHARMACOKINETICS

Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units : the SAFE-ICU study

Jason A. RobertsFekade B. SimeJeffrey LipmanMaria Patricia Hernandez-MitreJoao Pedro BaptistaRoger J. BruggemannJai DarvallJan De WaeleGeorge DimopoulosJean-Yves Lefrant et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Be-SNAP : the Belgian Sepsis National Action Plan

Annelies MondelaersFebe Van de VoordeHarlinde PeperstraeteKen DewitteJan De WaeleIlse MalfaitPatrick Van de VoordeErika VlieghePieter DepuydtPeter Pype et al.

A1 Journal Article in FRONTIERS IN PUBLIC HEALTH

Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA) : an international prospective multicenter cohort study (vol 49, pg 517, 2023)

Romain SonnevilleEtienne de MontmollinDamien ContouRicard FerrerMohan GurjarKada KloucheBenjamine SartonSophie DemeretPierre BaillyDaniel da Silva et al.

Development and validation of the Sequential Organ Failure Assessment (SOFA)-2 score

Otavio T. RanzaniMervyn SingerJorge I. F. SalluhManu Shankar-HariDavid PilcherJoana Berger-EstilitaCraig M. CoopersmithNicole P. JuffermansJohn LaffeyMatti Reinikainen et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Does artificial intelligence close gaps in clinical pharmacology in the ICU?

Matthias GijsenJan De Waele

Editorial material

Early detection of OXA-48 producing Klebsiella pneumoniae with the use of rapid antibiotic susceptibility testing

Emilie De MuynckStien VandendriesscheAnne-Sophie MessiaenKristen DecommerDiana Huis in 't VeldJan De WaeleJerina Boelens

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Environmental sustainability in intensive care : an international survey of intensive care professionals'views, practices and proposals to the European Society of Intensive Care Medicine

Katerina IliopoulouMarc LeoneNicole HunfeldRicard FerrerHeather BaidMarlies OstermannGaetano ScaramuzzoHugo TouwAna-Maria IoanMaria Theodorakopoulou et al.

A1 Journal Article in JOURNAL OF CRITICAL CARE

Evaluating early mobilisation in critically ill COVID-19 patients : secondary analysis from the ESICM UNITE-COVID-II multicentre observational study

Maximilian MarkusMaximilian LindholzNils DaumAnne PohrtElie AzoulayMaurizio CecconiGiuseppe CiterioThomas De CorteFrantisek DuskaLaura Galarza et al.

A1 Journal Article in ANAESTHESIA CRITICAL CARE & PAIN MEDICINE

Impact of reporting rapid susceptibility results in Gram negative bloodstream infections : a real world prospective study

Anne-Sophie MessiaenStien VandendriesscheEmilie De MuynckGregory StrubbeLiesbet De BusPetra SchelstraeteKristen DecommerSanne De SmetAlexander SoetensLeslie Naesens et al.

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Management of adult sepsis in resource-limited settings : global expert consensus statements using a Delphi method

Louise ThwaitesPrashant NasaBrett AbbenbroekVu Quoc DatSimon FinferArthur KwizeraLowell LingSuzana M. LoboRobert SintoDita Aditianingsih et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Meropenem and piperacillin/tazobactam optimised dosing regimens for critically ill patients receiving renal replacement therapy

Jason A. RobertsMarta UlldemolinsXin LiuJoao P. BaptistaIrma BilgramiClement BoidinAlexander BrinkmannPedro CastroGordon ChoiLouise Cole et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Mortality, functional outcome and health-related quality of life in patients with necrotizing skin- and soft tissue infections in the ICU : protocol of a multinational prospective cohort study (SKIN-ICU)

Tomas UrbinaMartin Bruun MadsenCamille HuaChristian EckmannMuhammed ElhadiMohan GurjarGennaro De PascaleFarid ZandJohanna HastbackaRicard Ferrer Rocca et al.

A1 Journal Article in INFECTIOUS DISEASES NOW

On the future of guidelines

W. Joost WiersingaMorten Hylander MollerJan De WaeleHallie C. Prescott

Editorial material

Positive communication for decreasing burnout in intensive-care-unit staff : a cluster-randomized trial

Elie AzoulaySheila N. MyatraGabriel Heras La CalleSamir JaberCarole BoulangerOktay DemirkyranMaria TheodorakopoulouJose-Artur PaivaYaseen M. ArabiGaston Burghi et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Preferences and attitudes on acetate- versus lactate-buffered crystalloid solutions for intravenous fluid therapy : an international survey

Karen Louise EllekjaerPraleene SivapalanSheila N. MyatraLasse GronningsaeterJohanna HastbackaPaul J. YoungAndrew J. BoyleMarlies OstermannCarmen A. PfortmuellerIeva Jovaisiene et al.

A1 Journal Article in ACTA ANAESTHESIOLOGICA SCANDINAVICA

Preferences for albumin use in adult intensive care unit patients with shock : an international survey (vol 68, pg 1234, 2024)

P. SivapalanK. L. EllekjaerA. PernerMorten Hylander MøllerAnders GranholmLasse GrønningsæterMarlies OstermannRob Mac SweeneyMaria CronhjortJohanna Hästbacka et al.

Rationale and methodological approach underlying the development of the Sequential Organ Failure Assessment (SOFA)-2 Score

Rui MorenoAndrew RhodesOtavio RanzaniJorge I. F. SalluhJoana Berger-EstilitaCraig M. CoopersmithNicole P. JuffermansJohn LaffeyMatti ReinikainenAry Serpa Neto et al.

A1 Journal Article in JAMA NETWORK OPEN

Shortening antibiotic therapy duration for hospital-acquired bloodstream infections in critically ill patients : a causal inference model from the international EUROBACT-2 database

Lena GajdosNiccolo BuettiAlexis TabahStephane RucklyMurat AkovaFrederik SjovalKostoula ArvantiJan De WaeleHendrik BrachtFrancois Barbier et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Source control in bloodstream infections in patients with sepsis, septic shock, or requiring ICU admission : a scoping review with recommendations for standardizing research

Alexis TabahJan De WaeleNathalie Ssi Yan KaiAbdullah Tarik AslanNiccolo BuettiJean-Francois TimsitEmma BallardLars ErikssonKevin B. LauplandJeffrey Lipman

A1 Journal Article in INTENSIVE CARE MEDICINE

The design of predictive and uncertainty-calibrated treatment models for the intensive care unit

Jarne VerhaegheSofie Van HoeckeJan De WaeleFemke Ongenae

The green ICU : how to interpret green? A multiple perspective approach

Elisabeth SmaleHeather BaidMarko BalanForbes McgainScott McalistarJan De WaeleJan Carel DiehlErik van RaaijMichel van GenderenDick Tibboel et al.

A1 Journal Article in CRITICAL CARE

The impact of intensive care strain on patients' outcomes : a multinational observational cohort (UNITE-COVID) study

Katharina KohlerThomas De CorteMassimiliano GrecoPedro PovoaMaurizio CecconiMarlies OstermannJan De WaeleAndrew Conway MorrisJolien Van Hecke[missing] UNITE-COVID Investigators

A1 Journal Article in CRITICAL CARE

The multifaceted role of the gastrointestinal system in the ICU : recent trends and future directions

Editorial material

The weekend effect in critically ill patients with severe infections in Japanese intensive care units : a multicenter retrospective cohort study

Teiko KawahigashiTaisuke JoTetsuya KomuroJan De WaeleLiesbet De BusAkihiro TakabaAkira KuriyamaAtsuko KobayashiChie TanakaHideki Hashi et al.

A2 Journal Article in THERAPEUTIC ADVANCES IN INFECTIOUS DISEASE

Towards trustful machine learning for antimicrobial therapy using an explainable artificial intelligence dashboard

Thomas De CorteJarne VerhaegheFemke OngenaeJan De WaeleSofie Van Hoecke

A1 Journal Article in APPLIED SCIENCES-BASEL

Unraveling mitochondrial pyruvate dysfunction to mitigate hyperlactatemia and lethality in sepsis

Louise NuyttensMarah HeyerickGeike HeremansElise MoensMaxime RoesCéline Van DenderLiesbet De BusJohan DecruyenaereJan De WaeleJolien Vandewalle et al.

A1 Journal Article in CELL REPORTS

2024

A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death

Céline Van DenderSteven TimmermansVille PaakinahoTineke VanderhaeghenJolien VandewalleMaarten ClaesBruno GarciaBart RomanJan De WaeleSiska Croubels et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

An overview of point-of-care testing for infections in critically ill patients

Alena MoermanJan De WaeleJerina Boelens

A1 Journal Article in EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Antibiotic dose optimisation in the critically ill : targets, evidence and future strategies

Christopher J. DyerJan De WaeleJason A. Roberts

A1 Journal Article in CURRENT OPINION IN CRITICAL CARE

Antimicrobial stewardship and molecular diagnostics : a symbiotic approach to combating resistance in the ED and ICU

Jan De WaeleJerina Boelens

A1 Journal Article in CURRENT OPINION IN CRITICAL CARE

Antimicrobial stewardship in the intensive care unit : evolving challenges and data science opportunities

Thomas De CorteJan De WaeleSofie Van HoeckePieter Depuydt

Cardiac surgery-associated acute kidney injury : exploring epidemiology, impact of hemodynamics, and the role of biomarkers

Wim VandenbergheEric HosteJan De Waele

Characteristics of co-infection and secondary infection amongst critically ill COVID-19 patients in the first two waves of the pandemic

Thomas De CorteKatharina KohlerMaurizio CecconiJan De WaeleAndrew Conway MorrisElie AzoulayGiuseppe CiterioAndy Conway MorrisFrantisek DuskaPaul Elbers et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Clinical outcomes in combination versus mono antibiotic therapy in ICU admitted patients with a suspected infection : a substudy of the DIANA study

Nima TanhaIlja Areskog LejbmanLiesbet De BusGennaro De PascaleJose Garnacho-MonteroMarc LeoneShigeki FujitanJan De WaeleGustav TorissonFredrik Sjovall

A1 Journal Article in JOURNAL OF CRITICAL CARE

Continuous vs intermittent β-lactam antibiotic infusions in critically ill patients with sepsis : the BLING III randomized clinical trial

Joel M. DulhuntyStephen J. BrettJan De WaeleDorrilyn RajbhandariLaurent BillotMenino O. CottaJoshua S. DavisSimon FinferNaomi E. HammondSerena Knowles et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Designing a pharmacokinetic machine learning model for optimizing beta-lactam antimicrobial dosing in critically ill patients

Jarne VerhaegheThomas De CorteJan De WaeleFemke OngenaeSofie Van Hoecke

Empirical carbapenems or piperacillin/tazobactam for infections in intensive care : an international retrospective cohort study

Nick MeierMarie Warrer MunchAnders GranholmAnders PernerFrederik Boetius HertzBalasubramanian VenkateshNaomi E. HammondQiang LiLiesbet De BusJan De Waele et al.

A1 Journal Article in ACTA ANAESTHESIOLOGICA SCANDINAVICA

Empowering excellence in intensive care : a vision for the European Society of Intensive Care Medicine

Elie AzoulayJan De WaeleMaurizio Cecconi

Editorial material

Environmental sustainability and antimicrobials : an underestimated problem with far-reaching consequences

Jan De WaeleIsabel Leroux-RoelsAndrew Conway-Morris

A1 Journal Article in INTENSIVE CARE MEDICINE

Environmental sustainability in intensive care : the path forward : an ESICM Green Paper

Jan De WaeleNicole HunfeldHeather BaidRicard FerrerKaterina IliopoulouAna-Maria IoanMarc LeoneMarlies OstermannGaetano ScaramuzzoMaria Theodorakopoulou et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Epidemiology and risk factors for mortality in critically ill patients with pancreatic infection

Marie DejonckheereMassimo AntonelliKostoula ArvanitiKoen BlotBen CreaghBrownDylan W. de LangeJan De WaeleMieke DeschepperYalim DikmenGeorge Dimopoulos et al.

A2 Journal Article in JOURNAL OF INTENSIVE MEDICINE

Family centeredness of care : a cross-sectional study in intensive care units part of the European society of intensive care medicine

Elie AzoulayNancy Kentish-BarnesCarole BoulangerGiovanni MistralettiMargo van MolGabriel Heras-La CalleElisa EstenssoroPeter Vernon van HeerdenMaria-Cruz Martin DelgadoAnders Perner et al.

A1 Journal Article in ANNALS OF INTENSIVE CARE

HELLO : a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals

Elie AzoulayNancy Kentish BarnesSheila Nainan-MyatraMaria-Cruz Martin DelgadoYaseen ArabiCarole BoulangerGiovanni MistralettiMaria TheodorakopoulouVernon Van HeerdenJose-Artur Paiva et al.

A2 Journal Article in INTENSIVE CARE MEDICINE EXPERIMENTAL

Hospital-acquired bloodstream infections in critically ill cirrhotic patients : a post-hoc analysis of the EUROBACT-2 international cohort study

Hannah WozniakAlexis TabahFrancois BarbierStephane RucklyAmbre LoiodiceMurat AkovaMarc LeoneAndrew Conway MorrisMatteo BassettiKostoula Arvaniti et al.

A1 Journal Article in ANNALS OF INTENSIVE CARE

Importance of timely and adequate source control in sepsis and septic shock

A2 Journal Article in JOURNAL OF INTENSIVE MEDICINE

International cross-sectional survey on current and updated definitions of intra-abdominal hypertension and abdominal compartment syndrome

Prashant NasaRobert D. WiseMarije SmitStefan AcostaScott D'AmoursWilliam Beaubien-SoulignyZsolt BodnarFederico CoccoliniNeha S. DangayachWojciech Dabrowski et al.

A1 Journal Article in WORLD JOURNAL OF EMERGENCY SURGERY

Intra-abdominal infection and sepsis in immunocompromised intensive care unit patients : disease expression, microbial aetiology, and clinical outcomes

José-Artur PaivaJordi RelloChristian EckmannMassimo AntonelliKostoula ArvanitiDespoina KoulentiGeorgios PapathanakosGeorge DimopoulosMieke DeschepperStijn Blot et al.

A1 Journal Article in EUROPEAN JOURNAL OF INTERNAL MEDICINE

Invasive fungal diseases in adult patients in intensive care unit (FUNDICU) : 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM

Matteo BassettiDaniele R. GiacobbeChristina Agvald-OhmanMurat AkovaAna Alastruey-IzquierdoSevtap Arikan-AkdagliElie AzoulayStijn BlotOliver A. CornelyManuel Cuenca-Estrella et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

No improvement in mortality among critically ill patients with carbapenems as initial empirical therapy and more detection of multi-drug resistant pathogens associated with longer use : a post hoc analysis of a prospective cohort study

Junki IshiiMitsuaki NishikimiLiesbet De BusJan De WaeleAkihiro TakabaAkira KuriyamaAtsuko KobayashiChie TanakaHideki HashiHideki Hashimoto et al.

A1 Journal Article in MICROBIOLOGY SPECTRUM

Position paper on the reporting of norepinephrine formulations in critical care from the Society of Critical Care Medicine and European Society of Intensive Care Medicine Joint Task Force

Patrick M. WieruszewskiMarc LeoneBenjamin Skov Kaas-HansenSiddharth DugarMatthieu LegrandCathrine A. McKenzieBrittany D. Bissell TurpinAntonio MessinaPrashant NasaChrista A. Schorr et al.

A1 Journal Article in CRITICAL CARE MEDICINE

Predictors of augmented renal clearance based on iohexol plasma clearance in critically ill children

Evelyn DhontTatjana Van Der HeggenEvelien SnauwaertJef WillemsSiska CroubelsJoris DelangheJan De WaeleRoos ColmanJohan Vande WallePeter De Paepe et al.

A1 Journal Article in PEDIATRIC NEPHROLOGY

Preferences for albumin use in adult intensive care unit patients with shock : an international survey

Praleene SivapalanKaren Louise EllekjaerAnders PernerMorten Hylander MollerAnders GranholmLasse GronningsaeterMarlies OstermannRob Mac SweeneyMaria CronhjortJohanna Hastbacka et al.

A1 Journal Article in ACTA ANAESTHESIOLOGICA SCANDINAVICA

Prolonged vs intermittent infusions of β-lactam antibioticsin adults with sepsis or septic shock : a systematic review and meta-analysis

Mohd H. Abdul-AzizNaomi E. HammondStephen J. BrettMenino O. CottaJan De WaeleAnthony DevauxGian Luca Di TannaJoel M. DulhuntyHatem ElkadyLars Eriksson et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Selective digestive tract decontamination implementation

Jeroen SchoutenMargo van MolJan De Waele

Editorial material

Strengthening intensive care : addressing challenges and embracing opportunities

Elie AzoulayMaurizio CecconiJan De Waele

Editorial material

TDM of antibiotics in ICU patients : added value of unbound and oral fluid concentrations

Sofie ColmanVeronique StoveJan De WaeleJerina BoelensAlain Verstraete

The environmental impact of laboratory measurements in high-resource ICUs

Marlies OstermannJan De WaeleJoerg C. Schefold

Editorial material

The impact of the massive open online course C19_SPACE during the COVID-19 pandemic on clinical knowledge enhancement : a study among medical doctors and nurses

Maurizio CecconiAnita BarthGergo Jozsef SzollosiGizella Melania IstrateJoel AlexandreFrantisek DuskaStefan J. SchallerCarole BoulangerJohannes MellinghoffPeter Waldauf et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

The role of centre and country factors on process and outcome indicators in critically ill patients with hospital-acquired bloodstream infections

Niccolo BuettiAlexis TabahNour SettiStephane RucklyFrancois BarbierMurat AkovaAbdullah Tarik AslanMarc LeoneMatteo BassettiAndrew Conway Morris et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Variability in forgoing life-sustaining treatment practices in critically Ill patients with hospital-acquired bloodstream infections : a secondary analysis of the EUROBACT-2 international cohort

Hannah WozniakAlexis TabahJan De WaeleJean-Francois TimsitNiccolo BuettiLiesbet De Bus[missing] EUROBACT-2 Study Grp[missing] European Soc Intensive Care Med ESICM[missing] European Soc Clinical Microbiology[missing] Infect Dis ESCMID Study Grp Infections Critically Ill Patients ESGCIP et al.

A1 Journal Article in CRITICAL CARE

2023

A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units : the SAFE-ICU study

Jason A. RobertsFekade SimeJeffrey LipmanMaria Patricia Hernandez-MitreJoao Pedro BaptistaRoger J. BrueggemannJai DarvallJan De WaeleGeorge DimopoulosJean-Yves Lefrant et al.

A1 Journal Article in CRITICAL CARE AND RESUSCITATION

Adequate antimicrobial dosing in critically ill patients receiving extracorporeal membrane oxygenation : where to go from here?

Isabel SprietJan De Waele

Editorial material

Advancing precision-based antimicrobial dosing in critically ill patients

Menino O. CottaJeffrey LipmanJan De Waele

Editorial material

Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA) : an international prospective multicenter cohort study

Romain SonnevilleEtienne de MontmollinDamien ContouRicard FerrerMohan GurjarKada KloucheBenjamine SartonSophie DemeretPierre BaillyDaniel da Silva et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Concentration target attainment after therapeutic drug monitoring of linezolid in critically ill patients

Jolien LanguiPieter De CockNick VerougstraeteJerina BoelensAnnemie SomersJan De WaeleBarbara Claus

Early mobilisation in critically ill COVID-19 patients : a subanalysis of the ESICM-initiated UNITE-COVID observational study

Philipp KlossMaximilian LindholzAnnette MilnikElie AzoulayMaurizio CecconiGiuseppe CiterioThomas De CorteFrantisek DuskaLaura GalarzaMassimiliano Greco et al.

A1 Journal Article in ANNALS OF INTENSIVE CARE

Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients : the EUROBACT-2 international cohort study

Alexis TabahNiccolo BuettiQuentin StaiqulyStephane RucklyMurat AkovaAbdullah Tarik AslanMarc LeoneAndrew Conway MorrisMatteo BassettiKostoula Arvaniti et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia

Ignacio Martin-LoechesAntoni TorresBlin NagavciStefano AlibertiMassimo AntonelliMatteo BassettiLieuwe BosJames ChalmersLennie DerdeJan De Waele et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia (Apr, 10.1007/s00134-023-07033-8, 2023)

Ignacio Martin-LoechesAntoni TorresBlin NagavciStefano AlibertiMassimo AntonelliMatteo BassettiLieuwe D. BosJames D. ChalmersLennie DerdeJan De Waele et al.

Expectations and readiness of ICU physicians to use AI in clinical practice : a multicentre survey study

Thomas De CorteLaura Van MaeleJona DietvorstJarne VerhaegheAnn VandendriesscheN De NeveSofie VanderhaeghenA DumoulinW. TemmermanB Dewulf et al.

Ferroptosis and pyroptosis signatures in critical COVID-19 patients

Cédric PelemanSamya Van CoillieSymen LigthartSze Men ChoiJan De WaelePieter DepuydtDominique BenoitHANNAH SCHAUBROECKSven M. FrancqueKarolien Dams et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Fluid management in intra-abdominal hypertension

Manu L. N. G. MalbrainPrashant NasaInneke De laetJan De WaeleRita JacobsRobert WiseLuca MalbrainWojciech DabrowskiAdrian Wong

Bookchapter in Rational use of intravenous fluids in critically ill patients

Generalizable calibrated machine learning models for real-time atrial fibrillation risk prediction in ICU patients

Jarne VerhaegheThomas De CorteChristopher M. SauerTom HendriksOlivier W.M. ThijssensFemke OngenaePaul ElbersJan De WaeleSofie Van Hoecke

A1 Journal Article in INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS

Optimized treatment of nosocomial peritonitis

Jan De WaeleFederico CoccoliniLeonel LagunesEmilio MasedaStefano RauseiInes Rubio-PerezMaria TheodorakopoulouKostoula Arvanti

A1 Journal Article in ANTIBIOTICS-BASEL

Pathogen-based target attainment of optimized continuous infusion dosing regimens of piperacillin-tazobactam and meropenem in surgical ICU patients : a prospective single center observational study

Thomas De CorteJarne VerhaegheSofie DhaeseSarah Van VoorenJerina BoelensAlain VerstraeteVeronique StoveFemke OngenaeLiesbet De BusPieter Depuydt et al.

A1 Journal Article in ANNALS OF INTENSIVE CARE

Potential of urine biomarkers CHI3L1, NGAL, TIMP-2, IGFBP7, and combinations as complementary diagnostic tools for acute kidney injury after pediatric cardiac surgery : a prospective cohort study

Wim VandenbergheJorien De LoorKatrien FrancoisKristof VandekerckhoveIngrid HerckJohan Vande WalleHarlinde PeperstraeteThierry BovéDaniël De WolfLieve Nuytinck et al.

A1 Journal Article in DIAGNOSTICS

Selective digestive decontamination-Pro

Jan De WaeleIsabel Leroux-RoelsPieter Depuydt

Editorial material

Ten golden rules for optimal antibiotic use in hospital settings : the WARNING call to action

Massimo SartelliPhilip S. BarieFederico CoccoliniMohamed AbbasLilian M. AbboGulnora K. AbdukhalilovaYishak AbrahamSalisu AbubakarFikri M. Abu-ZidanYusuff Adebayo Adebisi et al.

A1 Journal Article in WORLD JOURNAL OF EMERGENCY SURGERY

The Sequential Organ Failure Assessment (SOFA) Score : has the time come for an update?

Rui MorenoAndrew RhodesLise PiquilloudGlenn HernandezJukka TakalaHayley B. GershengornMiguel TavaresCraig M. CoopersmithSheila N. MyatraMervyn Singer et al.

A1 Journal Article in CRITICAL CARE

The spine intra-abdominal pressure (SIAP) trial : a prospective, observational, single arm, monocenter study looking at the evolutions of the IAP prior, during and after spine surgery

Pram DepauwF. van EijsC. WensingR. GeuzeH. van SantbrinkM. MalbrainJan De Waele

A1 Journal Article in JOURNAL OF CLINICAL NEUROSCIENCE

Tight blood-glucose control without early parenteral nutrition in the ICU

J. GunstY. DebaveyeF. GuizaJ. DuboisA. De BruynD. DauweE. De TroyM. P. CasaerG. De VliegerR. Haghedooren et al.

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

Towards adequate and automated antibiotic dosing

Alexander JanssenJan De WaelePaul W. G. Elbers

Editorial material

Towards artificial intelligence as a decision support tool to combat AMR in the ICU

Thomas De CorteJarne VerhaegheFemke OngenaeSofie Van HoeckeJan De Waele

A4 Journal Article in ICU MANAGEMENT

2022

A guideline for therapeutic drug monitoring of linezolid in critically ill patients

Jolien LanguiPieter De CockNick VerougstraeteJerina BoelensDiana Huis in 't VeldAnnemie SomersJan De WaeleBarbara Claus

An international survey of adherence to Surviving Sepsis Campaign Guidelines 2016 regarding fluid resuscitation and vasopressors in the initial management of septic shock

Eden BittonShmuel ZimmermanLuciano Cesar Pontes AzevedoDan BenhamouMaurizio CecconiJan De WaeleJeffrey LipmanIgnacio Martin-LoechesRomain PirracchioThomas W.L. Scheeren et al.

A1 Journal Article in JOURNAL OF CRITICAL CARE

Antibiotic dosing in sustained low-efficiency daily dialysis (SLEDD) : basic concepts and dosing strategies

Anna LeeJan De WaeleJeffrey Lipman

A1 Journal Article in JOURNAL OF CRITICAL CARE

Artificial intelligence in infection management in the ICU

Thomas De CorteSofie Van HoeckeJan De Waele

A1 Journal Article in CRITICAL CARE

Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave : the global UNITE-COVID study

Massimiliano GrecoThomas De CorteAri ErcoleElie AzoulayGiuseppe CiterioAndy Conway MorrisFrantisek DuskaPaul ElbersSharon EinavLui Forni et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave : the global UNITE-COVID study (vol 48, pg 690, 2022)

Massimiliano GrecoThomas De CorteAri ErcoleMassimo AntonelliElie AzoulayGiuseppe CiterioAndy Conway MorrisGennaro De PascaleFrantisek DuskaPaul Elbers et al.

Co-infection and ICU-acquired infection in COIVD-19 ICU patients : a secondary analysis of the UNITE-COVID data set

Andrew Conway MorrisKatharina KohlerThomas De CorteAri ErcoleHarm-Jan De GroothPaul W. G. ElbersPedro PovoaRui MoraisDespoina KoulentiSameer Jog et al.

A1 Journal Article in CRITICAL CARE

Comment on : 'Penetration of antibacterial agents into pulmonary epithelial lining fluid : an update'

Pieter-Jan De SutterJan De WaeleAn Vermeulen

A1 Journal Article in CLINICAL PHARMACOKINETICS

Development and evaluation of uncertainty quantifying machine learning models to predict piperacillin plasma concentrations in critically ill patients

Jarne VerhaegheSofie DhaeseThomas De CorteDavid Vander MijnsbruggeHeleen AardemaJan G. ZijlstraAlain VerstraeteVeronique StovePieter ColinFemke Ongenae et al.

A1 Journal Article in BMC MEDICAL INFORMATICS AND DECISION MAKING

Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients : a descriptive analysis of the Eurobact II study

Niccolo BuettiAlexis TabahAmbre LoiodiceStephane RucklyAbdullah Tarik AslanGiorgia MontrucchioAndrea CortegianiNese SaltogluBircan KayaaslanFirdevs Aksoy et al.

A1 Journal Article in CRITICAL CARE

Effect of antiplatelet therapy on survival and organ support-free days in critically ill patients with COVID-19 : a randomized clinical trial

Charlotte A. BradburyPatrick R. LawlerSimon J. StanworthBryan J. McVerryZoe McQuiltenAlisa M. HigginsPaul R. MounceyFarah Al-BeidhKathryn M. RowanLindsay R. Berry et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effects of cascade reporting of susceptibility profiles for Enterobacterales on broad-spectrum antibiotics use and resistance

Laura HeiremanStien VandendriesscheLiselotte CoorevitsFranky BuyleJan De WaeleDirk VogelaersBruno VerhasseltJerina Boelens

A1 Journal Article in EUROPEAN JOURNAL OF HOSPITAL PHARMACY

Epidemiology and age-related mortality in critically ill patients with intra-abdominal infection or sepsis : an international cohort study

Kostoula ArvanitiGeorge DimopoulosMassimo AntonelliKoen BlotBen Creagh-BrownMieke DeschepperDylan de LangeJan De WaeleYalim DikmenChristian Eckmann et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine)

Mical PaulElena CarraraPilar RetamarThomas TängdénRoni BittermanRobert A. BonomoJan De WaeleGeorge L. DaikosMurat AkovaStephan Harbarth et al.

A1 Journal Article in CLINICAL MICROBIOLOGY AND INFECTION

Fluid management, intra-abdominal hypertension and the abdominal compartment syndrome : a narrative review

Rita JacobsRobert D. WiseIvan MyatchinDomien VanhonackerAndrea MininiMichael MekeireleAndrew W. KirkpatrickBruno M. PereiraMichael SugrueBart De Keulenaer et al.

A1 Journal Article in LIFE-BASEL

Impact of mean perfusion pressure and vasoactive drugs on occurrence and reversal of cardiac surgery-associate acute kidney injury : a cohort study

Wim VandenbergheThierry BovéFilip De SomerIngrid HerckKatrien FrancoisHarlinde PeperstraeteAnnemieke DhondtThomas MartensHANNAH SCHAUBROECKTine Philipsen et al.

A1 Journal Article in JOURNAL OF CRITICAL CARE

Infection control in the intensive care unit : expert consensus statements for SARS-CoV-2 using a Delphi method

Prashant NasaElie AzoulayArunaloke ChakrabartiJigeeshu V DivatiaRavi JainCamilla RodriguesVictor D RosenthalWaleed AlhazzaniYaseen M ArabiJan Bakker et al.

A1 Journal Article in LANCET INFECTIOUS DISEASES

Intra-abdominal hypertension and abdominal compartment syndrome

A1 Journal Article in CURRENT OPINION IN CRITICAL CARE

Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis

Gennaro De PascaleMassimo AntonelliMieke DeschepperKostoula ArvanitiKoen BlotBen Creagh BrownDylan de LangeJan De WaeleYalim DikmenGeorge Dimopoulos et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Prediction of cardiac surgery associated-acute kidney injury (CSA-AKI) by healthcare professionals and urine cell cycle arrest AKI biomarkers [TIMP-2]*[IGFBP7] : a single center prospective study (the PREDICTAKI trial)

Wim VandenbergheLien Van LaethemINGRID HERCKHarlinde PeperstraeteHANNAH SCHAUBROECKAlexander ZarbockMelanie MeerschAnnemieke DhondtSigurd DelangheJill Vanmassenhove et al.

A1 Journal Article in JOURNAL OF CRITICAL CARE

Predictive value of the renal resistive index in the immediate postoperative period after kidney transplantation on short- and long-term graft and patient outcomes

Stijn BogaertNicole SuchonosPrem Vignesh MohanAlexander DecruyenaerePhilippe DecruyenaereJan De WaeleFrank VermassenSteven Van LaeckePatrick PeetersTimm H. Westhoff et al.

A1 Journal Article in JOURNAL OF CRITICAL CARE

Science communication for young researchers : a short guide to showcasing all your hard work

Eva DegraeuweAnn RaesJohan Vande WalleJan De WaeleAnna Maria Wiesinger

Severe infections in the ICU : new perspectives and challenges

Editorial material

Source control in the management of sepsis and septic shock

Jan De WaeleMassimo GirardisIgnacio Martin-Loeches

Editorial material

The role of abdominal drain cultures in managing abdominal infections

Jan De WaeleJerina BoelensDirk Van de PutteDiana Huis in 't VeldTom Coenye

A1 Journal Article in ANTIBIOTICS-BASEL

Use of broad-spectrum antimicrobials for more than 72 h and the detection of multidrug-resistant bacteria in Japanese intensive care units : a multicenter retrospective cohort study

H YoshidaT MotohashiLiesbet De BusJan De WaeleA TakabaA KuriyamaA KobayashiC TanakaH HashiH Hashimoto et al.

A1 Journal Article in ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL

Variation in communication and family visiting policies in intensive care within and between countries during the Covid-19 pandemic : the COVISIT international survey

Alexis TabahMuhammed ElhadiEmma BallardAndrea CortegianiMaurizio CecconiTakeshi UnokiLaurą GalarzaRegis Goulart RosaFrancois BarbierElie Azoulay et al.

A1 Journal Article in JOURNAL OF CRITICAL CARE

Why we may need higher doses of beta-lactam antibiotics : introducing the 'maximum tolerable dose'

Sofie DhaeseEric HosteJan De Waele

A1 Journal Article in ANTIBIOTICS-BASEL

2021

A three-day antimicrobial course for community-acquired pneumonia? Still no evidence in intensive care unit

Marc LeoneAlexandre LopezCaroline UseroviciJan De Waele

Editorial material

Antimicrobial lessons from a large observational cohort on intra-abdominal infections in intensive care units

Dirk VogelaersStijn BlotAndries Van den BergeGuy FrancoisSonia LabeauKoen BlotMieke DeschepperJeffrey LipmanJan De WaeleTomas Vymazal et al.

A1 Journal Article in DRUGS

Antimicrobial stewardship in ICUs during the COVID-19 pandemic : back to the 90s?

Jan De WaeleL DerdeM Bassetti

Editorial material

Antimicrobial stewardship in the ICU in COVID-19 times : the known unknowns

Jeroen SchoutenJan De WaeleChristian LanckohrDespoina KoulentiNisrine HaddadNesrine RizkFredrik SjövallSouha S. KanjAlliance for the Prudent Use of Antibiotics (APUA)

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Antimicrobial stewardship, therapeutic drug monitoring and infection management in the ICU : results from the international A- TEAMICU survey

Christian LanckohrChristian BoeingJan De WaeleDylan W. de LangeJeroen SchoutenMenno PrinsMaarten NijstenPedro PovoaAndrew Conway MorrisHendrik Bracht

A1 Journal Article in ANNALS OF INTENSIVE CARE

Augmented renal clearance in critically ill COVID-19 patients : forewarned is forearmed

Sofie DhaeseHarlinde PeperstraeteEric HosteWim Van BiesenJan De Waele

Editorial material

Development and validation of a liquid chromatography high-resolution mass spectrometry orbitrap method for the sensitive quantification of amoxicillin, piperacillin, tazobactam and meropenem in human faeces

Sarah Van VoorenJan De WaeleJerina BoelensMichaël PoletVeronique StoveLynn VanhaeckeAlain Verstraete

A1 Journal Article in ANALYTICA CHIMICA ACTA

Empiric cone-beam CT-guided embolization in acute lower gastrointestinal bleeding

Laurens HermieElisabeth DhondtPeter VanlangenhoveJan De WaeleHelena DegrooteLuc Defreyne

A1 Journal Article in EUROPEAN RADIOLOGY

Initial antimicrobial management of sepsis

Michael S. NiedermanRebecca M. BaronLila BouadmaThierry CalandraNick DanemanJan De WaeleMarin H. KollefJeffrey LipmanGirish B. Nair

A1 Journal Article in CRITICAL CARE

Personal protective equipment and intensive care unit healthcare worker safety in the COVID-19 Era (PPE-SAFE) : an international survey (vol 59, pg 70, 2020)

Alexis TabahMahesh RamananKevin B. LauplandNiccolò BuettiAndrea CortegianiJohannes MellinghoffAndrew Conway MorrisLuigi CamporotaNathalie ZappellaMuhammed Elhadi et al.

Pharmacokinetics and pharmacodynamics of ceftolozane/tazobactam in critically ill patients with augmented renal clearance

David P. NicolauJan De WaeleJoseph L. KutiLuzelena CaroKajal B. LarsonBrian YuElaine GadzickiZhen ZengElizabeth G. RheeMatthew L. Rizk

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Pilot study of oral fluid and plasma meropenem and piperacillin concentrations in the intensive care unit

Sofie ColmanSofie DhaeseVeronique StoveJan De WaeleAlain G. Verstraete

A1 Journal Article in CLINICA CHIMICA ACTA

Protocol for an international, multicentre, prospective, observational study of nosocomial pneumonia in intensive care units : the PneumoINSPIRE study

Despoina KoulentiApostolos ArmaganidisKostoula ArvanitiStijn BlotChristian Brun-BuissonMaria DejaJan De WaeleBin DuJoel M DulhuntyJulia Garcia-Diaz et al.

A1 Journal Article in CRITICAL CARE AND RESUSCITATION

Surviving sepsis campaign : international guidelines for management of sepsis and septic shock 2021

Laura EvansAndrew RhodesWaleed AlhazzaniMassimo AntonelliCraig M. CoopersmithCraig FrenchFlávia R. MachadoLauralyn McintyreMarlies OstermannHallie C. Prescott et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts

Yasser SakrBruno FrancoisJordi Sole-ViolanKatarzyna KotfisUlrich JaschinskiAngel EstellaMarc LeoneStephan M. JakobXavier WitteboleLuis E. Fontes et al.

A1 Journal Article in CRITICAL CARE

The effect of renal replacement therapy and antibiotic dose on antibiotic concentrations in critically ill patients : data from the Multinational Sampling Antibiotics in Renal Replacement Therapy study

Jason A RobertsGavin JoyntAnna LeeGordon ChoiRinaldo BellomoSalmaan KanjiM Yugan MudaliarSandra L PeakeDianne StephensFabio Silvio Taccone et al.

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

The future of antimicrobial dosing in the ICU : an opportunity for data science

Thomas De CortePaul ElbersJan De Waele

A1 Journal Article in INTENSIVE CARE MEDICINE

The gastrointestinal system in critical care : current insights and perspectives

Editorial material

Une antibiothérapie de trois jours pour le traitement de la pneumonie communautaire ? Toujours pas de preuve en réanimation = A three-day antimicrobial course for community-acquired pneumonia? Still no evidence in intensive care unit

Marc LeoneAlexandre LopezCaroline UseroviciJan De Waele

Editorial material

2020

A clinician’s guide to management of intra-abdominal hypertension and abdominal compartment syndrome in critically ill patients

Inneke E. De LaetManu L. N. G. MalbrainJan De Waele

A1 Journal Article in CRITICAL CARE

A microbiologist consultant should attend daily ICU rounds

J SchoutenG De AngelisJan De Waele

Editorial material

Antimicrobial de-escalation as part of antimicrobial stewardship in intensive care : no simple answers to simple questions - a viewpoint of experts

Jan De WaeleJeroen SchoutenBojana BeovicAlexis TabahMarc Leone

A1 Journal Article in INTENSIVE CARE MEDICINE

Antimicrobial de-escalation in critically ill patients : a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP)

Alexis TabahMatteo BassettiMarin H KollefJean-Ralph ZaharJosé-Artur PaivaJean-Francois TimsitJason A RobertsJeroen SchoutenHelen GiamarellouJordi Rello et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure : the DIANA study

Liesbet De BusPieter DepuydtJohan SteenSofie DhaeseKen De SmetAlexis TabahMurat AkovaMenino Osbert CottaGennaro De PascaleGeorge Dimopoulos et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Antimicrobial de-escalation in the ICU : from recommendations to level of evidence

Ines LakbarJan De WaeleAlexis TabahSharon EinavIgnacio Martin-LoechesMarc Leone

A1 Journal Article in ADVANCES IN THERAPY

Antimicrobial therapeutic drug monitoring in critically ill adult patients : a Position Paper#

Mohd H. Abdul-AzizJan-Willem C. AlffenaarMatteo BassettiHendrik BrachtGeorge DimopoulosDeborah MarriottMichael N. NeelyJose-Artur PaivaFederico PeaFredrik Sjovall et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Conventional amphotericin B must be avoided in Candida infections

I Martin-LoechesJan De WaeleJF TimsitM Bassetti

A1 Journal Article in INTENSIVE CARE MEDICINE

Corrigendum to 'Early target attainment of continuous infusionpiperacillin/tazobactam and meropenem in critically ill patients : a prospective observational study' [Journal of Critical Care 52(2019) 75–79]

Sofie DhaeseAlexander ThooftAndras FarkasJeffrey LipmanAlain VerstraeteVeronique StoveJason A. RobertsJan De Waele

European intensive care physicians’ experience of infections due to antibiotic-resistant bacteria

Alain LepapeAstrid JeanJan De WaeleArnaud FriggeriAnne SaveyPhilippe VanhemsMarie Paule GustinDominique L. MonnetJosé Garnacho-MonteroAnke Kohlenberg

A1 Journal Article in ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL

Improving care for the ICU patient with suspected infection : a multidisciplinary perspective

M LeoneC PulciniJan De Waele

Editorial material

International variation in the management of severe COVID-19 patients

Elie AzoulayJan De WaeleRicard FerrerThomas StaudingerMarta BorkowskaPedro PovoaKaterina IliopoulouAntonio ArtigasStefan J. SchallerManu Shankar-Hari et al.

A1 Journal Article in CRITICAL CARE

Lung penetration, bronchopulmonary pharmacokinetic/pharmacodynamic profile and safety of 3 g of ceftolozane/tazobactam administered to ventilated, critically ill patients with pneumonia

Luzelena CaroDavid P NicolauJan De WaeleJoseph L KutiKajal B LarsonElaine GadzickiBrian YuZhen ZengAdedayo AdedoyinElizabeth G Rhee

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Multidrug-resistant bacteria in ICU : fact or myth

Jan De WaeleJerina BoelensIsabel Leroux-Roels

A1 Journal Article in CURRENT OPINION IN ANESTHESIOLOGY

Necrotizing skin and soft tissue infections in the intensive care unit

Marijke PeetermansNicolas de ProstChristian EckmannAnna Norrby-TeglundSteinar SkredeJan De Waele

A1 Journal Article in CLINICAL MICROBIOLOGY AND INFECTION

Organising international research in critical care medicine : current challenges and potential solutions

Jan De WaeleDylan W de Lange

Editorial material

Personal protective equipment and intensive care unit healthcare worker safety in the COVID-19 era (PPE-SAFE) : an international survey

Alexis TabahMahesh RamananKevin B. LauplandNiccolò BuettiAndrea CortegianiJohannes MellinghoffAndrew Conway MorrisLuigi CamporotaNathalie ZappellaMuhammed Elhadi et al.

A1 Journal Article in JOURNAL OF CRITICAL CARE

Prevalence and outcomes of infection among patients in intensive care units in 2017

Jean-Louis VincentYasser SakrMervyn SingerIgnacio Martin-LoechesFlavia R. MachadoJohn C. MarshallSimon FinferPaolo PelosiLuca BrazziDita Aditianingsih et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prolonged versus intermittent infusion of β-lactam antibiotics : a systematic review and meta-regression of bacterial killing in preclinical infection models

Sofie DhaeseAaron HeffernanDavid LiuMohd Hafiz Abdul-AzizVeronique StoveVincent H. TamJeffrey LipmanJason A. RobertsJan De Waele

A1 Journal Article in CLINICAL PHARMACOKINETICS

Symptoms of burnout in intensive care unit specialists facing the COVID-19 outbreak

Elie Azoulay[missing] ESICMJan De WaeleRicard FerrerThomas StaudingerMarta BorkowskaPedro PovoaKaterina IliopoulouAntonio ArtigasStefan J. Schaller et al.

A1 Journal Article in ANNALS OF INTENSIVE CARE

Systematic reviews and meta-analyses of interventions in the Journal of Critical Care

Wan-Jie GuFernando ZampieriJan De Waele

Editorial material

Therapeutic drug monitoring of beta-lactam antibiotics in the ICU

Sofie DhaeseSarah Van VoorenJerina BoelensJan De Waele

A1 Journal Article in EXPERT REVIEW OF ANTI-INFECTIVE THERAPY

When not to start antibiotics : avoiding antibiotic overuse in the intensive care unit

Kerina J DennyJan De WaeleKevin B LauplandPatrick NA HarrisJeffrey Lipman

A1 Journal Article in CLINICAL MICROBIOLOGY AND INFECTION

When not to start antibiotics : avoiding antibiotic overuse in the intensive care unit (vol 26, pg 35, 2020)

K.J. DennyJan De WaeleK.B. LauplandP.N.A. HarrisJ. Lipman

2019

A practical approach to clinical antibiotic stewardship in the ICU patient with severe infection

Jan FierensPieter DepuydtJan De Waele

A1 Journal Article in SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis : BLING III

Jeffrey LipmanStephen J BrettJan De WaeleMenino O CottaJoshua S DavisSimon FinferParisa GlassSerena KnowlesShay McGuinnessJohn Myburgh et al.

A1 Journal Article in CRITICAL CARE AND RESUSCITATION

Antibiotic stewardship in sepsis management : toward a balanced use of antibiotics for the severely ill patient

Jan De WaeleSofie Dhaese

A1 Journal Article in EXPERT REVIEW OF ANTI-INFECTIVE THERAPY

Awareness and knowledge of intra-abdominal hypertension and abdominal compartment syndrome : results of a repeat, international, cross-sectional survey

Robert WiseReitze RodsethAnnika Reintam BlaserDerek J RobertsJan De WaeleAndrew W KirkpatrickBart L De KeulenaerManu LNG Malbrain

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

Clinical controversies in abdominal sepsis : insights for critical care settings

Ignacio Martin-LoechesJean François TimsitMarc LeoneJan De WaeleMassimo SartelliSteve KerriganLuciano Cesar Pontes AzevedoSharon Einav

A1 Journal Article in JOURNAL OF CRITICAL CARE

Continuous infusion of beta-lactam antibiotics in the critically ill : unresolved pharmacokinetic and pharmacodynamic issues

Sofie DhaeseJan De WaeleVeronique StovePieter Depuydt

Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units : protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project

M BassettiL ScudellerDR GiacobbeF LamothE RighiV ZuccaroC GrecchiC RebuffiM AkovaA Alastruey-Izquierdo et al.

A1 Journal Article in MYCOSES

Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients : a prospective observational study

Sofie DhaeseAlexander ThooftAndras FarkasJeffrey LipmanAlain VerstraeteVeronique StoveJason A. RobertsJan De Waele

A1 Journal Article in JOURNAL OF CRITICAL CARE

Elaboration of consensus clinical endpoints to evaluate antimicrobial treatment efficacy in future hospital-acquired/ventilator-associated bacterial pneumonia clinical trials

Emmanuel WeissJean-Ralph ZaharJeff AlderKarim AsehnouneMatteo BassettiMarc JM BontenJean ChastreJan De WaeleGeorge DimopoulosPhilippe Eggimann et al.

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Epidemiology of intra-abdominal infection and sepsis in critically ill patients : 'AbSeS', a multinational observational cohort study and ESICM Trials Group Project

Stijn BlotMassimo AntonelliKostoula ArvanitiKoen BlotBen Creagh-BrownDylan de LangeJan De WaeleMieke DeschepperYalim DikmenGeorge Dimopoulos et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients

Ignacio Martin-LoechesMassimo AntonelliManuel Cuenca-EstrellaGeorge DimopoulosSharon EinavJan De WaeleJose Garnacho-MonteroSouha S KanjFlavia R MachadoPhilippe Montravers et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

How I search for a sepsis source

Jan De WaeleYasser Sakr

Editorial material

Isavuconazole versus caspofungin in the treatment of candidemia and other invasive Candida infections : the ACTIVE Trial

Bart Jan KullbergClaudio ViscoliPeter G PappasJose VazquezLuis Ostrosky-ZeichnerColeman RotsteinJack D SobelRaoul HerbrechtGalia RahavSutep Jaruratanasirikul et al.

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Measuring antibiotics in exhaled air in critically ill, non-ventilated patients : a feasibility and proof of concept study

Jan HerregodtsSarah Van VoorenEvan DeschuyteneerSofie DhaeseVeronique StoveAlain VerstraeteJan De Waele

A1 Journal Article in JOURNAL OF CRITICAL CARE

Measuring unbound versus total piperacillin concentrations in plasma of critically ill patients : methodological issues and relevance

Sofie ColmanVeronique StoveJan De WaeleAlain Verstraete

A1 Journal Article in THERAPEUTIC DRUG MONITORING

Optimal and responsible use of antibiotics

Pieter DepuydtJan De Waele

A1 Journal Article in CURRENT OPINION IN CRITICAL CARE

Persistence of piperacillin concentrations after treatment discontinuation : in cauda venenum?

Jan De WaeleC Van EeckhoutPieterjan VanhaelewynMieke CarlierAlain VerstraeteVeronique Stove

A1 Journal Article in INTENSIVE CARE MEDICINE

Personalized antibiotic dosing for the critically ill

Jason A RobertsClaire RogerJan De Waele

Editorial material

Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem : a comparison of eight pharmacokinetic models

Sofie DhaeseAndras FarkasPieter ColinJeffrey LipmanVeronique StoveAlain VerstraeteJason A RobertsJan De Waele

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Rationalizing antimicrobial therapy in the ICU : a narrative review

Jean-François TimsitMatteo BassettiOlaf CremerGeorge DaikosJan De WaeleAndre KallilEric KipnisMarin KollefKevin LauplandJose-Artur Paiva et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Saturable elimination of piperacillin in critically ill patients : implications for continuous infusion

Sofie DhaesePieter ColinHelena WillemsA HeffernanBram GadeyneSarah Van VoorenPieter DepuydtEric HosteVeronique StoveAlain Verstraete et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Subtherapeutic piperacillin concentrations in neurocritical patients

Caroline DamenSofie DhaeseAlain VerstraeteVeronique StoveJan De Waele

A1 Journal Article in JOURNAL OF CRITICAL CARE

The significance of intra-abdominal pressure in neurosurgery and neurological diseases : a narrative review and a conceptual proposal

Paul RAM DepauwRob JM GroenJohannes Van LoonWilco C PeulManu LNG MalbrainJan De Waele

A1 Journal Article in ACTA NEUROCHIRURGICA

What happens after ICU discharge? : a within-hospital seamless care analysis of antimicrobial therapy

Barbara ClausJan De WaeleJolien LanguiPieter Depuydt

2018

A complete and multifaceted overview of antibiotic use and infection diagnosis in the intensive care unit : results from a prospective four-year registration

Liesbet De BusBram GadeyneJohan SteenJerina BoelensGeert ClaeysDominique BenoitJan De WaeleJohan DecruyenaerePieter Depuydt

A1 Journal Article in CRITICAL CARE

Antimicrobial resistance and antibiotic stewardship programs in the ICU : insistence and persistence in the fight against resistance : a position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance

Jan De WaeleMurat AkovaMassimo AntonelliRafael CantonJean CarletDaniel De BackerGeorge DimopoulosJosé Garnacho-MonteroJozef KeseciogluJeffrey Lipman et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

Jean-Louis VincentJean-Yves LefrantKatarzyna KotfisRahul NanchalIgnacio Martin-LoechesXavier WitteboleSamir G SakkaPeter PickkersRui MorenoYasser Sakr et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Continuous infusion piperacillin in critically ill patients : predicting concentrations using published population pharmacokinetic models

Sofie DhaeseAndras FarkasPieter ColinJason RobertsJeffrey LipmanAlain VerstraeteVeronique StoveJan De Waele

Effect of decompressive laparotomy on organ function in patients with abdominal compartment syndrome : a systematic review and meta-analysis

Lana Van DammeJan De Waele

A1 Journal Article in CRITICAL CARE

Emergence of antimicrobial resistance to piperacillin/tazobactam or meropenem in the ICU : intermittent versus continuous infusion : a retrospective cohort study

Sofie DhaeseMagalie De KezelMaxime CallantJerina BoelensLiesbet De BusPieter DepuydtJan De Waele

A1 Journal Article in JOURNAL OF CRITICAL CARE

Generic and optimized antibacterial dosing strategies in the critically ill

Bookchapter in Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically ill

Impact of AST meetings on antimicrobial therapy decisions in the ICU

Sofie DhaeseLiesbet De BusJerina BoelensLiselotte CoorevitsBruno VerhasseltPieter DepuydtJan De Waele

Optimal duration of antibiotic treatment in Gram-negative infections

Jan De WaeleIgnacio Martin-Loeches

A1 Journal Article in CURRENT OPINION IN INFECTIOUS DISEASES

Population pharmacokinetics of continuous infusion meropenem in critically ill patients : a comparison of eight approaches

Andras FarkasSofie DhaeseJason RobertsJeffrey LipmanVeronique StoveAlain VerstraeteJan De Waele

Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients

Sofie DhaeseJason A RobertsMieke CarlierAlain VerstraeteVeronique StoveJan De Waele

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Prolonged infusion of beta-lactam antibiotics in critically ill patients : revisiting the evidence

Sofie DhaeseVeronique StoveJan De Waele

Bookchapter in Annual update in intensive care and emergency medicine 2018

Quantitation of antibiotics in exhaled breath : a pilot study (ANTIBEX-trial)

Jan HerregodtsEvan DeschuyteneerMieke CarlierAlain VerstraeteVeronique StoveJan De Waele

Target attainment of empirically dosed continuous infusion of piperacillin/tazobactam and meropenem in critically ill patients

Sofie DhaeseAlexander ThooftAndras FarkasJason RobertsJeffrey LipmanAlain VerstraeteVeronique StoveJan De Waele

Very high intact-protein formula successfully provides protein intake according to nutritional recommendations in overweight critically ill patients : a double-blind randomized trial

Arthur RH van ZantenLaurent PetitJan De WaeleHans KieftJanneke de WildePeter van HorssenMarianne KlebachZandrie Hofman

A1 Journal Article in CRITICAL CARE

What every intensivist should know about the management of peritonitis in the intensive care unit

A2 Journal Article in REVISTA BRASILEIRA DE TERAPIA INTENSIVA

2017

Antimicrobial stewardship in ICU

Jeroen SchoutenJan De Waele

Bookchapter in Antimicrobial stewardship

Dosing of antibiotics in exhaled breath : a pilot study (ANTIBEX-trial)

EVAN DESCHUYTENEERJan HerregodtsSigrid DeprezMieke CarlierAlain VerstraeteJan De Waele

Early enteral nutrition in critically ill patients : ESICM clinical practice guidelines

Annika Reintam BlaserJoel StarkopfWaleed AlhazzaniMette M BergerMichael P CasaerAdam M DeaneSonja FruhwaldMichael HiesmayrCarole IchaiStephan M Jakob et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Higher fluid balance increases the risk of death from sepsis : results from a large international audit

Yasser SakrPaolo Nahuel Rubatto BirriKatarzyna KotfisRahul NanchalBhagyesh ShahStefan KlugeMary E SchroederJohn C MarshallJean-Louis Vincenton behalf of the Intensive Care Over Nations Investigators et al.

A1 Journal Article in CRITICAL CARE MEDICINE

Impact and management of abdominal compartment syndrome in patients with abdominal sepsis

Bookchapter in Abdominal sepsis : a multidisciplinary approach

Implementing antimicrobial stewardship in critical care : a practical guide

J SchoutenJan De Waele

Bookchapter in Annual update in intensive care and emergency medicine 2017

Management of intra-abdominal infections : recommendations by the WSES 2016 consensus conference

Massimo SartelliFausto CatenaFikri M Abu-ZidanLuca AnsaloniWalter L BifflMarja A BoermeesterMarco CeresoliOsvaldo ChiaraFederico CoccoliniJan De Waele et al.

A1 Journal Article in WORLD JOURNAL OF EMERGENCY SURGERY

Population pharmacokinetics of continuous infusion piperacillin in critically ill patients

Sofie DhaeseJason A RobertsMieke CarlierAlain VerstraeteVeronique StoveJan De Waele

Proceedings of resources for optimal care of acute care and emergency surgery consensus summit Donegal Ireland

M SugrueR MaierEE MooreM BoermeesterF CatenaF CoccoliniA LeppaniemiA PeitzmanG VelmahosL Ansaloni et al.

A1 Journal Article in WORLD JOURNAL OF EMERGENCY SURGERY

Stability of amoxicillin and amoxicillin/clavulanic acid reconstituted in isotonic saline

Mieke CarlierAlain VerstraeteJan De WaeleVeronique Stove

A1 Journal Article in JOURNAL OF CHEMOTHERAPY

The Global Alliance for Infections in Surgery : defining a model for antimicrobial stewardship : results from an international cross-sectional survey

Massimo SartelliFrancesco M LabricciosaPamela BarbadoroLeonardo PaganiLuca AnsaloniAdrian J BrinkJean CarletAshish KhannaAlain Chichom-MefireFederico Coccolini et al.

A1 Journal Article in WORLD JOURNAL OF EMERGENCY SURGERY

The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections

T TängdénV Ramos MartínTW FeltonEI NielsenS MarchandRJ BrüggemannJB BulittaM BassettiU TheuretzbacherBT Tsuji et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

To which extent can we decrease antibiotic duration in critically ill patients?

José Garnacho-MonteroAngel Arenzana-SeisdedosJan De WaeleMarin H Kollef

A1 Journal Article in EXPERT REVIEW OF CLINICAL PHARMACOLOGY

Update from the Abdominal Compartment Society (WSACS) on intra-abdominal hypertension and abdominal compartment syndrome : past, present, and future beyond Banff 2017

Andrew W KirkpatrickMichael SugrueJessica L McKeeBruno M PereiraDerek J RobertsJan De WaeleAri LeppaniemiJaneth C EjikeAnnika Reintam BlaserScott D'Amours et al.

Editorial material

2016

A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the intensive care unit

Alexis TabahMenino Osbert CottaJose Garnacho-MonteroJeroen SchoutenJason A RobertsJeffrey LipmanMark TaceyJean-François TimsitMarc LeoneJean Ralph Zahar et al.

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Abdominal sepsis

A1 Journal Article in CURRENT INFECTIOUS DISEASE REPORTS

Amended classification of the open abdomen

M BjörckAW KirkpatrickM CheathamM KaplanA LeppäniemiJan De Waele

A1 Journal Article in SCANDINAVIAN JOURNAL OF SURGERY

Antimicrobials : a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

M SartelliDG WeberE RuppeM BassettiBJ WrightL AnsaloniF CatenaF CoccoliniFM Abu-ZidanR Coimbra et al.

A1 Journal Article in WORLD JOURNAL OF EMERGENCY SURGERY

Decompressive laparotomy for abdominal compartment syndrome

Jan De WaeleE KimballM MalbrainI NesbittJ CohenV KaloianiR IvaturyM MoneDIETER DEBERGHM Björck

A1 Journal Article in BRITISH JOURNAL OF SURGERY

Diagnostic strategy and timing of intervention in infected necrotizing pancreatitis : an international expert survey and case vignette study

Janneke van GrinsvenSandra van BrunschotOlaf J BakkerThomas L BollenMarja A BoermeesterMarco J BrunoCornelis H DejongMarcel G DijkgraafCasper H van EijckPaul Fockens et al.

A1 Journal Article in HPB

Impact of de-escalation of beta-lactam antibiotics on the emergence of antibiotic resistance in ICU patients : a retrospective observational study

Liesbet De BusWOUTER DENYSJULIE CATTEEUWBram GadeyneKarel VermeulenJerina BoelensGeert ClaeysJan De WaeleJohan DecruyenaerePieter Depuydt

A1 Journal Article in INTENSIVE CARE MEDICINE

Intermittent axillary temperature measurement fails to detect fever in critically ill patients

Veerle BosschemNelly MauwsAlexander HeynemanDANIELLA VAN DER JEUGHTEric HosteJohan DecruyenaereJan De Waele

A1 Journal Article in MINERVA ANESTESIOLOGICA

Intra-abdominal hypertension and the abdominal compartment syndrome

Derek J RobertsJan De WaeleAndrew W KirkpatrickManu LNG Malbrain

Bookchapter in Surgical intensive care medicine

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? : an observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort

Mohd H Abdul-AzizJeffrey LipmanMurat AkovaMatteo BassettiJan De WaeleGeorge DimopoulosJoel DulhuntyKirsi-Maija KaukonenDespoina KoulentiClaude Martin et al.

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Long-term outcome in ICU patients with acute kidney injury treated with renal replacement therapy : a prospective cohort study

Wouter De CorteAnnemieke DhondtRaymond VanholderJan De WaeleJohan DecruyenaereVeerle SergoyneJoke VanhalstSTEFAAN CLAUSEric Hoste

A1 Journal Article in CRITICAL CARE

Permissive intraabdominal hypertension following complex abdominal wall reconstruction

Andrew W KirkpatrickDerek J RobertsJan De WaeleAnnika Reintam BlaserManu LNG MalbrainMartin BjorckZsolt J Balogh

A1 Journal Article in PLASTIC AND RECONSTRUCTIVE SURGERY

Reducing antibiotic use in the ICU : a time-based approach to rational antimicrobial use

Pieter DepuydtLiesbet De BusJan De Waele

Bookchapter in Annual update in intensive care and emergency medicine 2016

Therapeutic management of peritonitis : a comprehensive guide for intensivists

P MontraversStijn BlotG DimopoulosC EckmannP EggimannX GuiraoJA PaivaG SgangaJan De Waele

A1 Journal Article in INTENSIVE CARE MEDICINE

Understanding abdominal compartment syndrome

Jan De WaeleI De LaetML Malbrain

Editorial material

Understanding antibiotic stewardship for the critically ill

Jan De WaeleJeoffrey SchoutenG Dimopoulos

Editorial material

What about confidence intervals? : a word of caution when interpreting PTA simulations

Pieter ColinDouglas J EleveldStijn JonckheereJan Van BocxlaerJan De WaeleAn Vermeulen

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

2015

A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients

Mieke CarlierJason A RobertsVeronique StoveAlain VerstraeteJeffrey LipmanJan De Waele

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A user's guide to intra-abdominal pressure measurement

Michael SugrueJan De WaeleBart L De KeulenaerDerek J RobertsManu LNG Malbrain

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review

Mieke CarlierVeronique StoveSteven C WallisJan De WaeleAlain VerstraeteJeffrey LipmanJason A Roberts

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Augmented renal clearance and therapeutic monitoring of β-lactams

Andrew A UdyJan De WaeleJeffrey Lipman

Editorial material

Awareness and knowledge of intra-abdominal hypertension and abdominal compartment syndrome: results of an international survey

Robert WiseDerek J RobertsStefanie VanderveldenDieter DeberghJan De WaeleInneke De laetAndrew W KirkpatrickBart L De KeulenaerManu LNG Malbrain

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

Being overweight is associated with greater survival in ICU patients : results from the Intensive Care Over Nations audit

Yasser SakrIlmi AlhussamiRahul NanchalRichard G WunderinkTommaso PellisXavier WitteboleIgnacio Martin-LoechesBruno FrançoisMarc LeoneJean-Louis Vincent et al.

A1 Journal Article in CRITICAL CARE MEDICINE

Comparison of different equations to assess glomerular filtration in critically ill patients

Mieke CarlierAlexander DumoulinAlexander JanssenSven PicavetSteve VanthuyneRia Van EyndeRaymond VanholderJoris DelangheGert De SchoenmakereJan De Waele et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Epidemiology of augmented renal clearance in mixed ICU patients

Jan De WaeleAlexander DumoulinA JanssenEric Hoste

A1 Journal Article in MINERVA ANESTESIOLOGICA

Exploration of the pre-analytical stability of β-lactam antibiotics in plasma and blood: implications for therapeutic drug monitoring and pharmacokinetic studies

Mieke CarlierJan De WaeleAlain VerstraeteVeronique Stove

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

How to deal with an open abdomen?

Jan De WaeleMark KaplanMichael SugruePablo SibajaMartin Bjorck

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

Identification of quality indicators for the nutritional management of adult hospitalized patients by a modified Delphi process

L. VerbanckJan De WaeleI. DuysburghL. Van LooyD. YsebaertL. MerckxP. Ferdinande

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

Intra-abdominal hypertension and abdominal compartment syndrome in burns, obesity, pregnancy, and general medicine

Manu LNG MalbrainBart L De KeulenaerJun OdaInneke De laetJan De WaeleDerek J RobertsAndrew W KirkpatrickEdward KimballRao Ivatury

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

Intra-abdominal hypertension and abdominal compartment syndrome in pancreatitis, paediatrics, and trauma

Jan De WaeleJaneth C EjikeAri LeppäniemiBart L De KeulenaerInneke De laetAndrew W KirkpatrickDerek J RobertsEdward KimballRao IvaturyManu LNG Malbrain

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

Management of abdominal sepsis: a paradigm shift?

Ari LeppäniemiEdward J KimballInneke De laetManu MalbrainZsolt J BaloghJan De Waele

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

Measuring unbound versus total vancomycin concentrations in serum and plasma: methodological issues and relevance

Veronique StoveLouise CoeneMieke CarlierJan De WaeleTOM FIERSAlain Verstraete

A1 Journal Article in THERAPEUTIC DRUG MONITORING

Methodological background and strategy for the 2012−2013 updated consensus definitions and clinical practice guidelines from the abdominal compartment society

Andrew W KirkpatrickDerek J RobertsRoman JaeschkeJan De WaeleBart L De KeulenaerJuan DuchesneMartin BjorckAri LeppäniemiJaneth C EjikeMichael Sugrue et al.

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

Open abdomen management : challenges and solutions for the ICU team

Jan De WaeleMLNG Malbrain

Bookchapter in Annual update in intensive care and emergency medicine 2015

Patient tailored antibiotic therapy in critically ill patients

Mieke CarlierJan De WaeleVeronique Stove

Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients : data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients study

Mahipal G SinnollareddyJason A RobertsJeffrey LipmanMurat AkovaMatteo BassettiJan De WaeleKirsi-Maija KaukonenDespoina KoulentiClaude MartinPhilippe Montravers et al.

A1 Journal Article in CRITICAL CARE

Preventive and therapeutic strategies in critically ill patients with highly resistant bacteria

Matteo BassettiJan De WaelePhilippe EggimannJosè Garnacho-MonteroGunnar KahlmeterFrancesco MenichettiDavid P NicolauJose Arturo PaivaMario TumbarelloTobias Welte et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Randomized Trial of Micafungin for the Prevention of Invasive Fungal Infection in High-Risk Liver Transplant Recipients

Faouzi SalibaAndreas PascherOlivier CointaultPierre-François LaterreCarlos CerveraJan De WaeleUmberto CilloRóbert M LangerManuela LuganoBo Göran-Ericzon et al.

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Stability of generic brands of meropenem reconstituted in isotonic saline

Mieke CarlierVeronique StoveAlain VerstraeteJan De Waele

A1 Journal Article in MINERVA ANESTESIOLOGICA

Subtleties in practical application of prolonged infusion of β-lactam antibiotics

Jan De WaeleJeffrey LipmanMieke CarlierJason A Roberts

Editorial material

Targeted temperature management and neuroprognostication after cardiac arrest: a survey in Belgium

Fabio Silvio TacconeKirsten ColpaertJan De WaeleAnnick De WeerdtGreet HermansDidier LedouxGeert MeyfroidtIsabelle MichauxThierry SottiauxXavier Wittebole

A1 Journal Article in RESUSCITATION

Task force on management and prevention of Acinetobacter baumannii infections in the ICU

José Garnacho-MonteroGeorge DimopoulosGaryphallia PoulakouMurat AkovaJosé Miguel CisnerosJan De WaeleNicola PetrosilloHarald SeifertJean François TimsitJordi Vila et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

The abdominal compartment syndrome : evolving concepts and future directions

Jan De WaeleManu LNG MalbrainAndrew W Kirkpatrick

Editorial material

The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs

Alexis TabahJan De WaeleJeffrey LipmanJean Ralph ZaharMenino Osbert CottaGreg BartonJean-François TimsitJason A Roberts

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Ultrafast quantification of β-lactam antibiotics in human plasma using UPLC-MS/MS

Mieke CarlierVeronique StoveJan De WaeleAlain Verstraete

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

What every ICU clinician needs to know about the cardiovascular effects caused by abdominal hypertension

Manu LNG MalbrainJan De WaeleBart L De Keulenaer

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

WSACS : the Abdominal Compartment Society : a Society dedicated to the study of the physiology and pathophysiology of the abdominal compartment and its interactions with all organ systems

Andrew W. KirkpatrickJan De WaeleInneke De laetBart De KeulenaerScott D'AmoursMartin BjoerckZsolt J. BaloghAri LeppaeniemiMark KaplanJaneth Chiaka Ejike et al.

Editorial material

2014

'Piece' of mind: end of life in the intensive care unit: statement of the Belgian Society of Intensive Care Medicine

Jean-Louis VincentMiet SchetzJan De WaeleStéphan Clément de ClétyIsabelle MichauxThierry SottiauxEric HosteDidier LedouxAnnick De WeerdtAlexander Wilmer

A1 Journal Article in JOURNAL OF CRITICAL CARE

Abdominal infections in the intensive care unit : characteristics, treatment and determinants of outcome

Jan De WaeleJeffrey LipmanYasser SakrJohn C MarshallPhilippe VanhemsCasiano Barrera GrobaMarc LeoneJean-Louis Vincent

A1 Journal Article in BMC INFECTIOUS DISEASES

Acute pancreatitis

A1 Journal Article in CURRENT OPINION IN CRITICAL CARE

Aminoglycosides for life-threatening infections: a plea for an individualized approach using intensive therapeutic drug monitoring

Jan De WaeleN De Neve

A1 Journal Article in MINERVA ANESTESIOLOGICA

An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units

Gloria WongAlexander BrinkmanRussell J BenefieldMieke CarlierJan De WaeleNajoua El HelaliOtto FreyStephan HarbarthAngela HuttnerBrett McWhinney et al.

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Assessment of the worldwide burden of critical illness : the Intensive Care Over Nations (ICON) audit

Jean-Louis VincentJohn C MarshallSilvio A Namendys-SilvaBruno FrançoisIgnacio Martin-LoechesJeffrey LipmanKonrad ReinhartMassimo AntonelliPeter PickkersHassane Njimi et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Beta-lactam antibiotic dosing during continuous renal replacement therapy: how can we optimize therapy?

Jan De WaeleMieke Carlier

Editorial material

Clasificación internacional y multidisciplinaria de la pancreatitis aguda : edición española 2013

E Maraví-PomaE Patchen DellingerCE ForsmarkP LayerP LévyT ShimosegawaAK SiriwardenaG UomoDC WhitcombJA Windsor et al.

A1 Journal Article in MEDICINA INTENSIVA

DALI: Defining Antibiotic Levels in Intensive care unit patients: are current beta-lactam antibiotic doses sufficient for critically ill patients?

Jason A RobertsSanjoy K PaulMurat AkovaMatteo BassettiJan De WaeleGeorge DimopoulosKirsi-Maija KaukonenDespoina KoulentiClaude MartinPhilippe Montravers et al.

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Development of antibiotic treatment algorithms based on local ecology and respiratory surveillance cultures to restrict the use of broad-spectrum antimicrobial drugs in the treatment of hospital-acquired pneumonia in the intensive care unit : a retrospective analysis

Liesbet De BusLIES SAERENSBram GadeyneJerina BoelensGeert ClaeysJan De WaeleDominique BenoitJohan DecruyenaerePieter Depuydt

A1 Journal Article in CRITICAL CARE

Does consistent piperacillin dosing result in consistent therapeutic concentrations in critically ill patients?: a longitudinal study over an entire antibiotic course

Mieke CarlierSofie CarretteVeronique StoveAlain VerstraeteJan De Waele

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients?: data from the multinational DALI study

Stijn BlotDespoina KoulentiMurat AkovaMatteo BassettiJan De WaeleGeorge DimopoulosKirsi-Maija KaukonenClaude MartinPhilippe MontraversJordi Rello et al.

A1 Journal Article in CRITICAL CARE

Efficacy and safety of moxifloxacin in hospitalized patients with secondary peritonitis : pooled analysis of four randomized phase III trials

Jan De WaeleJose M TelladoGuenter WeissJeffrey AlderFrank KruesmannPierre ArvisTajamul HussainJoseph S Solomkin

A1 Journal Article in SURGICAL INFECTIONS

Efficacy of micafungin in invasive candidiasis caused by common Candida species with special emphasis on non-albicans Candida species

Oliver A CornelyJose VazquezJan De WaeleRobert BettsColeman RotsteinMarcio NucciPeter G PappasAndrew J Ullmann

A1 Journal Article in MYCOSES

Extended versus bolus infusion of meropenem and piperacillin: a pharmacokinetic analysis

Jan De WaeleMieke CarlierEric HostePieter DepuydtJohan DecruyenaereSteven C WallisJeffrey LipmanJason A Roberts

A1 Journal Article in MINERVA ANESTESIOLOGICA

High versus low blood-pressure target in septic shock

Andrew W KirkpatrickDerek J RobertsJan De Waele

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

High-protein enteral nutrition enriched with immune-modulating nutrients vs standard high-protein enteral nutrition and nosocomial infections in the ICU: a randomized clinical trial

Arthur RH van ZantenFranois SztarkUdo X KaisersSiegfried ZielmannThomas W FelbingerArmin R SablotzkiJan De WaeleJean-François TimsitMarina LH HoningDidier Keh et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

How to treat infections in a surgical intensive care unit

Jan De WaeleLiesbet De Bus

A2 Journal Article in BMC INFECTIOUS DISEASES

Impact of de-escalation on ICU patients' prognosis

Jan De WaeleMatteo BassettiIgnacio Martin-Loeches

Editorial material

Impact of infection on the prognosis of critically ill cirrhotic patients: results from a large worldwide study.

Thierry GustotPeter FelleiterPeter PickkersYasser SakrJordi RelloDimitrios VelissarisCharalampos PierrakosFabio S TacconePavel SevcikChristophe Moreno et al.

A1 Journal Article in LIVER INTERNATIONAL

Infections and use of antibiotics in patients admitted for severe acute pancreatitis : data from the EPIC II study

Jan De WaeleJordi RelloAntonio AnzuetoRui MorenoJeffrey LipmanYasser SakrPeter PickkersMarc LeoneAndrew FergusonLavi Oud et al.

A1 Journal Article in SURGICAL INFECTIONS

Is intra-abdominal hypertension a missing factor that drives multiple organ dysfunction syndrome?

Andrew W KirkpatrickDerek J RobertsJan De WaeleKevin Laupland

Editorial material

Moxifloxacin dosing in post-bariatric surgery patients

Pieter ColinDouglas J EleveldMichel StruysHuybrecht T'jollynLucas Van BortelJohannes RuigeJan De WaeleJan Van BocxlaerKoen Boussery

A1 Journal Article in BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures

Mieke CarlierMICHAEL NOEJason A RobertsVeronique StoveAlain VerstraeteJeffrey LipmanJan De Waele

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Protein binding of vancomycin: the impact of temperature on free plasma concentrations

Veronique StoveLouise CoeneMieke CarlierJan De WaeleAlain Verstraete

Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients

Jan De WaeleJ LipmanM AkovaM BassettiG DimopoulosM KaukonenD KoulentiC MartinP MontraversJ Rello et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Severe lactic acidosis in critically ill patients with acute kidney injury treated with renal replacement therapy

Wouter De CorteS VuylstekeJan De WaeleAnnemieke DhondtJohan DecruyenaereRaymond VanholderEric Hoste

A1 Journal Article in JOURNAL OF CRITICAL CARE

The role of abdominal compliance, the neglected parameter in critically ill patients : a consensus review of 16. Part 1 : definitions and pathophysiology

Manu L N G MalbrainDerek J RobertsInneke De laetJan De WaeleMichael SugrueAlexander SchachtruppJuan DuchesneGabriëlle van RamshorstBart De KeulenaerAndrew W Kirkpatrick et al.

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

The role of abdominal compliance, the neglected parameter in critically ill patients : a consensus review of 16. Part 2 : measurement techniques and management recommendations

Manu L N G MalbrainInneke De laetJan De WaeleMichael SugrueAlexander SchachtruppJuan DuchesneGabriëlle van RamshorstBart De KeulenaerAndrew W KirkpatrickSiavash Ahmadi-Noorbakhsh et al.

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

The use of bio-electrical impedance analysis (BIA) to guide fluid management, resuscitation and deresuscitation in critically ill patients : a bench-to-bedside review

Manu LNG MalbrainJohan HuyghWojciech DabrowskiJan De WaeleAnneleen StaelensJoost Wauters

A2 Journal Article in ANAESTHESIOLOGY INTENSIVE THERAPY

Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial

Jan De WaeleSofie CarretteMieke CarlierVeronique StoveJerina BoelensGeert ClaeysIsabel Leroux-RoelsEric HostePieter DepuydtJohan Decruyenaere et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: lessons from the DALI study

J. A. RobertsVeronique StoveJan De WaeleB SipinkoskiB McWhinneyJPJ UngererM AkovaM BassettiG DimopoulosK-M Kaukonen et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

What is new in the use of aminoglycosides in critically ill patients?

Dimitrios K MatthaiouJan De WaeleGeorge Dimopoulos

Editorial material

2013

A survey of beta-lactam antibiotics and vancomycin dosing strategies in intensive care units and general wards in Belgian hospitals.

Franky BuyleJohan DecruyenaereJan De WaelePaul M TulkensThijs Van AudenrodePieter DepuydtGeert ClaeysHugo RobaysDirk Vogelaers

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Augmented renal clearance is a common finding with worse clinical outcome in critically ill patients receiving antimicrobial therapy

Barbara ClausEric HosteKirsten ColpaertHugo RobaysJohan DecruyenaereJan De Waele

A1 Journal Article in JOURNAL OF CRITICAL CARE

Consensus strategies for the nonoperative management of patients with blunt splenic injury : a Delphi study

Dominique C OlthofCornelius H van der VliesPieter JoosseOtto M van DeldenGregory J JurkovichJC Goslingson behalf of the PYTHIA Collaboration GroupJan De Waele

A1 Journal Article in JOURNAL OF TRAUMA AND ACUTE CARE SURGERY

Diagnosis and management of temperature abnormality in ICUs : a EUROBACT investigators' survey

Daniel J NivenKevin B LauplandAlexis TabahAurélien VesinJordi RelloDespoina KoulentiGeorge DimopoulosJan De WaeleJean-François Timsit

A1 Journal Article in CRITICAL CARE

Einteilung des Schweregrads der akuten Pankreatitis : internationale, multidisziplinäre klinische Klassifikation auf Basis pathogenetischer Determinanten : Deutsche Version 2013

P LayerEP DellingerCE ForsmarkP LévyE Maraví-PomaT ShimosegawaAK SiriwardenaG UomoDC WhitcombJA Windsor et al.

A1 Journal Article in ZEITSCHRIFT FUR GASTROENTEROLOGIE

Factors associated with inadequate early vancomycin levels in critically ill patients treated with continuous infusion

Jan De WaeleI DanneelsPieter DepuydtJohan DecruyenaereM BourgeoisEric Hoste

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Gastrointestinal symptoms during the first week of intensive care are associated with poor outcome : a prospective multicentre study

Annika Reintam BlaserMartijn PoezeManu LNG MalbrainMartin BjörckHeleen M Oudemans-van StraatenJoel Starkopfthe Gastro-Intestinal Failure Trial GroupJan De WaeleDIETER DEBERGH

A1 Journal Article in INTENSIVE CARE MEDICINE

IAP/APA evidence-based guidelines for the management of acute pancreatitis

Marc BesselinkHjalmar van SantvoortMartin FreemanTimothy GardnerJulia MayerleSanthi Swaroop VegeJens WernerPeter BanksColin McKayCarlos Fernandez-del Castillo et al.

A1 Journal Article in PANCREATOLOGY

Identifying patients at risk for augmented renal clearance in the ICU : limitations and challenges

Mieke CarlierJan De Waele

Editorial material

Intra-abdominal hypertension : definitions, monitoring, interpretation and management

Manu LNG MalbrainInneke E De laetJan De WaeleAndrew W Kirkpatrick

A2 Journal Article in BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY

Intra-abdominal hypertension and the abdominal compartment syndrome : updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome

Andrew W KirkpatrickDerek J RobertsJan De WaeleRoman JaeschkeManu LNG MalbrainBart De KeulenaerJuan DuchesneMartin BjorckAri LeppaniemiJaneth C Ejike et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Meropenem and piperacillin/tazobactam prescribing in critically ill patients : does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?

Mieke CarlierSofie CarretteJason A RobertsVeronique StoveAlain VerstraeteEric HosteJohan DecruyenaerePieter DepuydtJeffrey LipmanSteven C Wallis et al.

A1 Journal Article in CRITICAL CARE

Optimizing β-lactam antibiotic therapy in the critically ill : moving towards patient-tailored antibiotic therapy

Mieke CarlierVeronique StoveJan De Waele

Bookchapter in Annual update in intensive care and emergency medicine 2013

Pancreatic stone protein for predicting outcome in peritonitis : limitations and challenges

Editorial material

Population pharmacokinetics and dosing simulations of amoxicillin/clavulanic acid in critically ill patients

Mieke CarlierMICHAEL NOEJan De WaeleVeronique StoveAlain VerstraeteJeffrey LipmanJason A Roberts

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Randomised clinical trial of moxifloxacin versus ertapenem in complicated intra-abdominal infections: results of the PROMISE study

Jan De WaeleJM TelladoJ AlderP ReimnitzM JensenB HampelP Arvis

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

2012

DALI : Defining Antibiotic Levels in Intensive care unit patients : a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic

Jason A RobertsJan De WaeleGeorge DimopoulosDespoina KoulentiClaude MartinPhilippe MontraversJordi RelloAndrew RhodesTherese StarrSteven C Wallis et al.

A1 Journal Article in BMC INFECTIOUS DISEASES

Determinant-based classification of acute pancreatitis severity : an international multidisciplinary consultation

E Patchen DellingerChristopher E ForsmarkPeter LayerPhilippe LévyEnrique Maraví-PomaMaxim S PetrovTooru ShimosegawaAjith K SiriwardenaGeneroso UomoDavid C Whitcomb et al.

A1 Journal Article in ANNALS OF SURGERY

Epidemiology of contrast-associated acute kidney injury in ICU patients: reply to Valette and du Cheyron

Eric HosteSEVERINE DOOMJan De WaeleLouke DelrueLuc DefreyneDominique BenoitJohan Decruyenaere

A1 Journal Article in INTENSIVE CARE MEDICINE

Essentials for selecting antimicrobial therapy for intra-abdominal infections

Stijn BlotJan De WaeleDirk Vogelaers

A1 Journal Article in DRUGS

Gastrointestinal function in intensive care patients : terminology, definitions and management: recommendations of the ESICM Working Group on Abdominal Problems

Annika Reintam BlaserManu LNG MalbrainJoel StarkopfSonja FruhwaldStephan M JakobJan De WaeleJan-Peter BraunMartijn PoezeClaudia Spies

A1 Journal Article in INTENSIVE CARE MEDICINE

Management of necrotizing skin and soft tissue infections

A1 Journal Article in EXPERT REVIEW OF ANTI-INFECTIVE THERAPY

Prospektive, randomisierte, double-dummy, doppelblinde, multizentrische Studie zum Vergleich der Sicherheit und Wirksamkeit von Moxifloxacin i.v. mit Ertapenem i.v. bei Patienten mit komplizierten intraabdominellen Infektionen: Ergebnisse der PROMISE-Studie

O KollmarM SchillingJan De WaeleJM TelladoJ AlderP ReimnitzM JensenB HampelP Arvis

Quantification of seven β-lactam antibiotics and two β-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method

Mieke CarlierVeronique StoveJason A RobertsERIC VAN DE VELDEJan De WaeleAlain Verstraete

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Renal physiology in the critically ill obese patient

Eric HosteJan De Waele

Bookchapter in Critical care management of the obese patient

TDM based dose optimization of piperacillin and meropenem: a randomized controlled trial

Jan De WaeleSofie CarretteMieke CarlierVeronique StoveEric HostePieter DepuydtJohan DecruyenaereAlain Verstraete

What's behind the failure of emerging antibiotics in the critically ill?: understanding the impact of altered pharmacokinetics and augmented renal clearance

Andrew A UdyJason A RobertsJan De WaeleDavid L PatersonJeffrey Lipman

Editorial material

2011

Determinants of prescription and choice of empirical therapy for hospital-acquired and ventilator-associated pneumonia

J RelloM UlldemolinsT LisboaD. KoulentiR ManezI Martin-LoechesJan De WaeleC PutensenM GuvenM Deja et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Does femoral venous pressure measurement correlate well with intrabladder pressure measurement?: a multicenter observational trial

Bart L De KeulenaerAdrian RegliWojcieh DabrowskiVaxtang KaloianiZsolt BodnarJavier Izura CeaA Andrey LitvinWendy A DavisAnne-Marie PalermoJan De Waele et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Epidemiology of contrast-associated acute kidney injury in ICU patients: a retrospective cohort analysis

Eric HosteSEVERINE DOOMJan De WaeleLouke DelrueLuc DefreyneDominique BenoitJohan Decruyenaere

A1 Journal Article in INTENSIVE CARE MEDICINE

Intra-abdominal hypertension and abdominal compartment syndrome

Jan De WaeleInneke De laetAndrew W KirkpatrickEric Hoste

A1 Journal Article in AMERICAN JOURNAL OF KIDNEY DISEASES

Nonoperative management of intra-abdominal hypertension and abdominal compartment syndrome : evolving concepts

Bart L De KeulenaerJan De WaeleManu LNG Malbrain

A1 Journal Article in AMERICAN SURGEON

Rational use of antimicrobials in patients with severe acute pancreatitis

A1 Journal Article in SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Serum urea concentration is probably not related to outcome in ICU patients with AKI and renal replacement therapy

Wouter De CorteRaymond VanholderAnnemieke DhondtJan De WaeleJohan DecruyenaereCHRISTIAN DANNEELSSTEFAAN CLAUSEric Hoste

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Temporary abdominal closure techniques

Jan De WaeleAri K Leppäniemi

A1 Journal Article in AMERICAN SURGEON

Variability of CT contrast enhancement in the pancreas : a cause for concern?

Louke DelruePETER BLANCKAERTDokus MertensJan De WaeleWim CeelenEric AchtenPhilippe Duyck

A1 Journal Article in PANCREATOLOGY

2010

A step-up approach, or open necrosectomy for necrotizing pancreatitis

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

Abdominal decompression for abdominal compartment syndrome in critically ill patients: a retrospective study

Jan De WaeleLiesbeth DesenderInneke De laetWim CeelenPiet PattynEric Hoste

A1 Journal Article in ACTA CLINICA BELGICA

Abdominal decompression for intra-abdominal hypertension after simultaneous pancreas-kidney transplantation

Tania DecosterFrank VermassenPatrick PeetersEric HosteJan De Waele

A1 Journal Article in CLINICAL TRANSPLANTATION

Acute pancreatitis: radiologic scores in predicting severity and outcome

Louke DelrueJan De WaelePhilippe Duyck

A1 Journal Article in ABDOMINAL IMAGING

Antimicrobial prophylaxis in liver transplant patients: a multicenter survey endorsed by the European Liver and Intestine Transplant Association

Els VandecasteeleJan De WaeleDominique VandijckStijn BlotDirk VogelaersXavier RogiersHans Van VlierbergheJohan DecruyenaereEric Hoste

A1 Journal Article in TRANSPLANT INTERNATIONAL

De-escalation after empirical meropenem treatment in the intensive care unit: fiction or reality?

Jan De WaeleMariska RavytsPieter DepuydtStijn BlotJohan DecruyenaereDirk Vogelaers

A1 Journal Article in JOURNAL OF CRITICAL CARE

Early source control in sepsis

Editorial material

How to remove accumulated iodine in burn-injured patients

Sunny ElootAnnemieke DhondtEric HosteAlain VerstraeteJan De WaeleKirsten ColpaertHenk HoeksemaFiona TrompRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Intra-abdominal hypertension, prone ventilation, and abdominal suspension

Chad G BallAndrew W KirkpatrickPaolo PelosiJan De Waele

A1 Journal Article in JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Intra-abdominal hypertension: does it influence the physiology of prone ventilation?

Andrew W KirkpatrickPaolo PelosiJan De WaeleManu LNG MalbrainChad G BallMaureen O MeadeHenry T StelfoxKevin B Laupland

A1 Journal Article in CRITICAL CARE

Intra-abdominal pressure measurement using a U-tube technique: caveat emptor!

Jan De WaeleMichael L CheathamZsolt BaloghMartin BjorckScott D'AmoursBart De KeulenaerRao IvaturyAndrew W KirkpatrickAri LeppaniemiManu Malbrain et al.

A1 Journal Article in ANNALS OF SURGERY

Modulation of seizure threshold by vagus nerve stimulation in an animal model for motor seizures

Veerle De HerdtJan De WaeleRobrecht RaedtTine WyckhuysRIEM EL TAHRYKristl VonckWytse WadmanPaul Boon

A1 Journal Article in ACTA NEUROLOGICA SCANDINAVICA

Necrotizing fasciitis complicated by fatal multiple organ dysfunction due to Pasteurella multocida infection: a case report

Filip StillaertLuc De BaerdemaekerJan De WaeleGeert ClaeysPhillip BlondeelStan Monstrey

A1 Journal Article in ACTA CLINICA BELGICA

Sodium bicarbonate for prevention of contrast-induced acute kidney injury: a systematic review and meta-analysis

Eric HosteJan De WaeleSofie GevaertShigehiko UchinoJohn A Kellum

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

The waiting is over: the first clinical outcome study of the treatment of intra-abdominal hypertension has arrived!

Jan De WaeleInneke De laet

Editorial material

Thrombocytopenia and outcome in critically ill patients with bloodstream infection

Dominique VandijckStijn BlotJan De WaeleEric HosteKoenraad VandewoudeJohan Decruyenaere

A1 Journal Article in HEART & LUNG

Use of antibiotics in severe acute pancreatitis

A1 Journal Article in EXPERT REVIEW OF ANTI-INFECTIVE THERAPY

Ventilator-associated pneumonia in trauma patients is associated with lower mortality : results from EU-VAP study

M MagretR Amaya-VillarJ GarnachoT LisboaE DiazJan De WaeleM DejaE MannoJ Rellothe EU-VAP/CAP study group et al.

A1 Journal Article in JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

2009

ADMINISTRATION OF VANCOMYCIN USING A STANDARDIZED PROTOCOL: DO WE ACHIEVE THERAPEUTIC SERUM CONCENTRATION IN THE INITIAL PHASE IN CRITICALLY ILL PATIENTS?

I. DanneelsJan De WaelePieter DepuydtJohan DecruyenaereEric Hoste

ADRENAL FUNCTION IN PATIENTS WITH INTRA-ABDOMINAL HYPERTENSION

Jan De WaeleInneke De laetEric Hoste

ADVERSE EFFECTS OF VOLUME THERAPY WITH HES SOLUTIONS ON KIDNEY FUNCTION: META-ANALYSIS OF PROSPECTIVE, RANDOMIZED CONTROLLED TRIALS

M PavilonisJan De WaeleJohan DecruyenaereD AdukauskieneEric Hoste

BACTERIEMIA IN PATIENTS WITH VENTILATOR ASSOCIATED PNEUMONIA: RESULTS FROM EU-VAP STUDY

M MagretM UlldemolinsJan De WaeleR ManezM DejaD KoulentiL PapazianS GardellinoT LisboaJ Rello

CAN FEMORAL CENTRAL VENOUS PRESSURE BE USED TO PREDICT INTRA-ABDOMINAL HYPERTENSION IN MECHANICALLY VENTILATED PATIENTS?

BL De KeulenaerJan De WaeleW DabrowskiJJI CeaGJR PicazaZ BodnarV KaloianiA LitvinIR Jenkins

Criteria for a diagnosis of abdominal compartment syndrome

M.L. CheathamJan De WaeleA. KirkpatrickM. SugrueM.L. MalbrainR.R. IvaturyZ. BaloghS. D'Amours

A1 Journal Article in CANADIAN JOURNAL OF SURGERY

Current options for IAP monitoring

Development and validation of a model for prediction of mortality in patients with acute burn injury

Stijn BlotNele BrusselaersStan MonstreyKoenraad VandewoudeJan De WaeleKirsten ColpaertJohan DecruyenaereM MalbrainC LafaireJ-P Fauville et al.

A1 Journal Article in BRITISH JOURNAL OF SURGERY

Epidemiology of infection in critically ill patients with acute renal failure

Emmelie ReynvoetDominique VandijckStijn BlotAnnemieke DhondtJan De WaeleSTEFAAN CLAUSFranky BuyleRaymond VanholderEric Hoste

A1 Journal Article in CRITICAL CARE MEDICINE

EVOLUTION IN COAGULATION PARAMETERS OVER THE FIRST 3 DAYS OF ICU ADMISSION IN SEPTIC SHOCK PATIENTS: IMPACT ON 30 DAY MORTALITY

Maarten BekaertJOKE NOLLETPieter DepuydtJohan DecruyenaereJan De WaeleCHRISTIAN DANNEELSStijn VansteelandtDominique Benoit

Future in clinical trials

IAH/ACS: The Rationale for Surveillance

Manu MalbrainInneke De laetJan De Waele

A1 Journal Article in WORLD JOURNAL OF SURGERY

Immunological and infectious complications of acute kidney injury

Eric HosteDominique VandijckJan De WaeleStijn Blot

Bookchapter in Critical care nephrology

Increased rat serum corticosterone suggests immunomodulation by stimulation of the vagal nerve

Veerle De HerdtLeen PuimègeJan De WaeleRobrecht RaedtTine WyckhuysRIEM EL TAHRYClaude LibertWytse WadmanPaul BoonKristl Vonck

A1 Journal Article in JOURNAL OF NEUROIMMUNOLOGY

Intra-abdominal hypertension in acute pancreatitis

Jan De WaeleAri Leppaniemi

A1 Journal Article in WORLD JOURNAL OF SURGERY

Intra-abdominal pressure measurements in lateral decubitus versus supine position

B. L. De KeulenaerM. L. CheathamJan De WaeleE. J. KimballB. PowellW. A. DavisI. R. Jenkins

A1 Journal Article in ACTA CLINICA BELGICA

Iodine toxicity as a cause of total atrioventricular block in burn patients

Kirsten ColpaertFiona TrompEls VandecasteeleAnnemieke DhondtJan De WaeleEric HosteJohan DecruyenaereStan Monstrey

Recommendations for research from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome

Jan De WaeleM.L. CheathamM.L. MalbrainA.W. KirkpatrickM. SugrueZ. BaloghR. IvaturyB. De KeulenaerE.J. Kimball

A1 Journal Article in Acta clinica belgica

Spectrum of practice in the diagnosis of nosocomial pneumonia in patients requiring mechanical ventilation in European intensive care units

D KoulentiT LisboaC Brun-BuissonW KruegerA MacorJ Sole-ViolanE DiazA TopeliJan De WaeleA Carneiro et al.

A1 Journal Article in CRITICAL CARE MEDICINE

THE EFFECT OF BODY MASS INDEX (BMI) ON INTRA-ABDOMINAL PRESSURE MEASUREMENTS

Bart De KeulenaerJan De WaeleMLNG Malbrain

THE EFFECT OF BODY POSITIONING ON INTRA-ABDOMINAL PRESSURE MEASUREMENTS

BL De KeulenaerJan De WaeleMLNG Malbrain

THE EFFECT OF POSITIVE END-EXPIRATORY PRESSURE (PEEP) ON INTRA-ABDOMINAL PRESSURE MEASUREMENTS

BL De KeulenaerJan De WaeleMLNG Malbrain

THE FATE OF ABSTRACTS PRESENTED AT WCACS2007

Jan De WaeleInneke De laetB De Keulenaer

The impact of body position on intra-abdominal pressure measurement: a multicenter analysis

Michael CheathamJan De WaeleInneke De laetBart De KeulenaerSandy WidderAndrew KirkpatrickAdrian CresswellManu MalbrainZsolt BodnarJorge Mejia-Mantilla et al.

A1 Journal Article in CRITICAL CARE MEDICINE

THE INFLUENCE OF DIURETIC USE AND NEGATIVE FLUID BALANCE ON INTRA-ABDOMINAL PRESSURE IN CRITICALLY ILL PATIENTS

Inneke De laetEric HosteJan De Waele

What is normal intra-abdominal pressure and how is it affected by positioning, body mass and positive end-expiratory pressure?

B.L. De KeulenaerJan De WaeleB. PowellM.L. Malbrain

A1 Journal Article in INTENSIVE CARE MEDICINE

What is the best dialysis strategy to treat burn-injured patients with elevated iodine blood levels

Sunny ElootAnnemieke DhondtJan De WaeleK ColpaertFiona TrompHendrik HoeksemaEric HosteAlain VerstraeteRaymond Vanholder

2008

A role for prophylactic antibiotics in necrotizing pancreatitis? Why we may never know the answer

Editorial material

Abdominal compartment syndrome in severe acute pancreatitis - When to decompress?

A1 Journal Article in EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY

Acute intestinal distress syndrome: the importance of intra-abdominal pressure

Manu MalbrainW. VidtsM. RavytsInneke De laetJan De Waele

A1 Journal Article in MINERVA ANESTESIOLOGICA

Acute kidney injury in the intensive care unit: it's the gene, stupid!

Eric HosteJan De Waele

A1 Journal Article in CRITICAL CARE MEDICINE

Antimicrobial prophylaxis in liver transplant patients: a multicenter survey supported by elita

Els VandecasteeleJan De WaeleStijn BlotDominique VandijckDirk VogelaersXavier RogiersM BourgeoisJohan DecruyenaereEric Hoste

Blood stream infections of abdominal origin in the intensive care unit: characteristics and determinants of death

Jan De WaeleEric HosteStijn Blot

A1 Journal Article in SURGICAL INFECTIONS

Continuous intra-abdominal pressure monitoring: this is the way to go!

Manu MalbrainInneke De laetJan De Waele

Editorial material

Costs and length of stay associated with antimicrobial resistance in acute kidney injury patients with bloodstream infection

Dominique VandijckStijn BlotJohan DecruyenaereRaymond VanholderJan De WaeleNorbert LameireSTEFAAN CLAUSJOHAN DE SCHUIJMERAnnemieke DhondtGerda Verschraegen et al.

A1 Journal Article in ACTA CLINICA BELGICA

Current insights in intra-abdominal hypertension and abdominal compartment syndrome: open the abdomen and keep it open!

Inneke E De LaetMariska RavytsWesley VidtsJody ValkJan De WaeleManu LNG Malbrain

A1 Journal Article in LANGENBECKS ARCHIVES OF SURGERY

European multicenter survey on antibiotic prophylaxis in liver transplant patients

Els VandecasteeleJan De WaeleStijn BlotDirk VogelaersXavier RogiersDominique VandijckMarc BourgeoisJohan DecruyenaereEric Hoste

Inter-observer reliability of different CT scoring systems in acute pancreatitis severity prediction

Louke DelrueJan De WaeleRobert GosselinPhilippe Duyck

Micafungin versus caspofungin for treatment of candidemia and other forms of invasive candidiasis (vol 45, pg 883, 2007)

PG PAPPASCMF ROTSTEINRF BETTSM NUCCID TALWARJan De WaeleJA VAZQUEZBF DUPONTDL HORNL OSTROSKY-ZEICHNER et al.

MULTICENTER SURVEY ON ANTIFUNGAL AND CYTOMEGALOVIRUS PROPHYLAXIS IN LIVER TRANSPLANT PATIENTS. STUDY SUPPORTED BY ELITA

Els VandecasteeleJan De WaeleStijn BlotDirk VogelaersXavier RogiersDominique VandijckM. BourgeoisJohan DecruyenaereEric Hoste

Non-invasive treatment of intra-abdominal hypertension: The search for the Holy Grail continues...

MLNG MALBRAINIne De LaetJan De Waele

Editorial material

Surgical decompression for abdominal compartment syndrome after emergency cardiac surgery

Annick De WolfJan PoelaertIngrid HerckJan De Waele

Editorial material

Temocillin: a valid option for directed therapy in ICU patients?

D Njdekembo ShangoPieter DepuydtStijn BlotKirsten ColpaertEric HosteSandra OeyenCarl RoosensDirk VogelaersJohan DecruyenaereJan De Waele

The effect of different reference transducer positions on intra-abdominal pressure measurement: a multicenter analysis

Jan De WaeleI. De LaetB. De KeulenaerS. WidderA. KirkpatrickA. CresswellM. MalbrainZ. BodnarJ. Mejia-MantillaR. Reis et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

The value of procalcitonin to diagnose infection in critically ill patient: caveat emptor!

Jan De WaeleEric HosteStijn BlotDirk Vogelaers

A1 Journal Article in CRITICAL CARE MEDICINE

Transvesical intra-abdominal pressure measurement using minimal instillation volumes: how low can we go?

Inneke De laetEric HosteJan De Waele

A1 Journal Article in INTENSIVE CARE MEDICINE

2007

A review of the safety of micafungin compared with liposomal amphotericin B in a large, phase III trial in patients with invasive candidiasis and candidaemia

AJ ULLMANNJan De WaeleR BETTSC ROTSTEINM NUCCIOA CORNELY

Abdominal compartment syndrome and acute pancreatitis

A. LeppaniemiK. JohanssonJan De Waele

A1 Journal Article in ACTA CLINICA BELGICA

An analysis of the efficacy of micafungin in Candida infections caused by non-albicans Candida species in phase III trials

OA CORNELYJan De WaeleR BETTSC ROTSTEINM NUCCIL KOVANDAC WUAJ ULLMANN

Antibiotic use and delayed source control in acute appendicitis

Jan De WaeleStijn Blot

A1 Journal Article in ARCHIVES OF SURGERY

Candida peritonitis

Stijn BlotKoenraad VandewoudeJan De Waele

A1 Journal Article in CURRENT OPINION IN CRITICAL CARE

Case report: Abdominal compartment syndrome after cardiac surgery

Annick De WolfJan De WaeleJan Poelaert

Clinical evaluation of the next generation foleymanometer (foleymanometer LV)

Jan De WaeleI DE LAETV BOSSCHEMC VERCLONCKEric Hoste

Clinical research in acute pancreatitis and the failure to predict severe disease

A1 Journal Article in ANNALS OF SURGERY

Complications of severe acute pancreatitis

Jan De WaeleFrancis ColardynDirk Vogelaers

Continuous intra-abdominal pressure monitoring

Z. BaloghJan De WaeleM.L.N.G. Malbrain

A1 Journal Article in ACTA CLINICA BELGICA

De alternatieve APACHE II score: betere voorspelling van de outcome

Dominique VandijckDOMINIQUE BenoitAnnick De WolfKirsten ColpaertM Van UtterbeeckEric HosteJan De WaeleStijn BlotJohan Decruyenaere

A2 Journal Article in KRITIEK - VLAAMSE VERENIGING VAN INTENSIEVE ZORGEN VERPLEEGKUNDIGEN

Efficacy of micafungin in patients with deep, invasive Candida infections

AJ ULLMANNJan De WaeleR BETTSC ROTSTEINM NUCCIL KOVANDAC WUD BUELLH DIEKMANNS KOBLINGER et al.

Extrapancreatic inflammation on abdominal computed tomography as an early predictor of disease severity in acute pancreatitis - Evaluation of a new scoring system

Jan De WaeleLouke DelrueEric HosteMartine De VosPhilippe DuyckFrancis Colardyn

A1 Journal Article in PANCREAS

Health implications of antimicrobial resistance for patients with acute kidney injury and bloodstream infection

Eric HosteDominique VandijckRaymond VanholderJan De WaeleNorbert LameireStefaan ClausJOHAN DE SCHUIJMERAnnemieke DhondtJohan DecruyenaereGerda Verschraegen et al.

A1 Journal Article in INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Intra-abdominal hypertension and the effect on renal function

Jan De WaeleInneke De laet

A1 Journal Article in ACTA CLINICA BELGICA

Intra-abdominal pressure measurement and abdominal compartment syndrome: The opinion of the World Society of the Abdominal Compartment Syndrome

Z BALOGHJan De WaeleA KIRKPATRICKM CHEATHAMS D'AMOURSM MALBRAIN

A1 Journal Article in CRITICAL CARE MEDICINE

Intraabdominal hypertension and abdominal compartment syndrome: We have paid attention, now it is time to understand!

Jan De WaeleInneke De laetM.L.N.G. Malbrain

A1 Journal Article in ACTA CLINICA BELGICA

Intraabdominal hypertension in patients with severe acute pancreatitis: An interim analysis of a prospective, multicenter study

Jan De WaeleB DE KEULENAERPF LATERRET DUGEMIER

Lumbotomy to decompress the retroperitoneum

Micafungin versus caspofungin for treatment of candidemia and other forms of invasive candidiasis

PG PAPPASCMF ROTSTEINRF BETTSM NUCCID TALWARJan De WaeleJA VAZQUEZBF DUPONTDL HORNL OSTROSKY-ZEICHNER et al.

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Micafungin versus caspofungin in patients with invasive candidiasis or candidaemia: a Phase III, randomised, double-blind, parallel group, non-inferiority study

B DupontJan De WaeleR BettsC RotsteinM NucciL ArnoldL KovandaC WuD Buell

Oral care practices in intensive care units: a survey of 59 European ICUs

J RELLOD KOULENTIStijn BlotR SIERRAE DIAZJan De WaeleA MACORK AGBAHTA RODRIGUEZ

A1 Journal Article in INTENSIVE CARE MEDICINE

Rational intraabdominal pressure monitoring: How to do it?

Jan De WaeleInneke De laetM.L.N.G. Malbrain

A1 Journal Article in ACTA CLINICA BELGICA

Relative adrenal insufficiency in patients with severe acute pancreatitis

Jan De WaeleEric HosteD BAERTK HENDRICKXD RIJCKAERTP THIBOP VAN BIERVLIETStijn BlotFrancis Colardyn

A1 Journal Article in INTENSIVE CARE MEDICINE

Results from the International Conference of Experts on Intra-Abdominal Hypertension and Abdominal Compartment Syndrome. II. Recommendations

ML CHEATHAMMLNG MALBRAINA KIRKPATRICKM SUGRUEM PARRJan De WaeleZ BALOGHA LEPPANIEMIC OLVERAR IVATURY et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Semicontinuous intra-abdominal pressure measurement using an intragastric Compliance catheter

Jan De WaeleFrederik BerrevoetKOEN REYNTJENSPIETER PLETINCKXIne De LaetEric Hoste

A1 Journal Article in INTENSIVE CARE MEDICINE

Severity prediction in acute pancreatitis: the role of early CT scan

Jan De WaeleLouke Delrue

A1 Journal Article in ABDOMINAL IMAGING

Study summary: The optimal reference point for intermittent transvesicular abdominal pressure monitoring in the critically ill patient with the head of bed in 30 degrees elevation

Jan De WaeleDieter Debergh

Survey on the perception and management of the abdominal compartment syndrome among Belgian surgeons

I DE LAETEric HosteJan De Waele

A1 Journal Article in ACTA CHIRURGICA BELGICA

Tertiary peritonitis and tertiary ACS: a perfect match?

Liesbeth DesenderIne De LaetFrank VermassenJan De Waele

The diagnosis of relative adrenal insufficiency: The long and winding road

Jan De WaeleEric Hoste

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The effect of body position on intra-abdominal pressure measurement: A multicenter analysis

ML CheathamJan De WaeleB De KeulenaerS WidderA KirkpatrickB CresswellM MalbrainZ BodnarJ MeijaR Reis et al.

The effect of neuromuscular blockers in patients with intra-abdominal hypertension

I DE LAETEric HosteE VERHOLENJan De Waele

A1 Journal Article in INTENSIVE CARE MEDICINE

The future of surgical critical care: A European perspective

Jan De WaeleEric Hoste

A1 Journal Article in CRITICAL CARE MEDICINE

The optimal zero reference transducer position for intraabdominal pressure measurement: A multicenter analysis

Jan De WaeleML CHEATHAMB DE KEULENAERS WIDDERA KIRKPATRICKB CRESSWELLM MALBRAINZ BODNARJ MEIJAR REIS et al.

The secondary and recurrent abdominal compartment syndrome

A.W. KirkpatrickJan De WaeleC.G. BallK. RansonS. WidderK.B. Laupland

A1 Journal Article in ACTA CLINICA BELGICA

The value of IL-6 in predicting the severity of acute pancreatitis

Jan De WaeleStijn Blot

A1 Journal Article in JOURNAL OF CLINICAL GASTROENTEROLOGY

Vagus nerve stimulation induced changes in corticosterone in rats

Veerle De HerdtClaude LibertJan De WaeleT DE SMEDTL WATERSCHOOTTine WyckhuysRIEM EL TAHRYAnnelies Van DyckeRobrecht RaedtKristl Vonck et al.

2006

Abdominal compartment syndrome: it's time to pay attention!

MLNG MALBRAINML CHEATHAMA KIRKPATRICKM SUGRUEJan De WaeleR IVATURY

A1 Journal Article in INTENSIVE CARE MEDICINE

Antimicrobial therapy for intra-abdominal infections: Guidelines from the Infectious Disease Advisory Board (IDAB)

PF LATERREE COLARDYNM DELMEEJan De WaeleJC LEGRANDJ VAN ELDEREA VERGISONDirk Vogelaers

A1 Journal Article in ACTA CHIRURGICA BELGICA

Current pharmacotherapeutic recommendations for acute pancreatitis

Jan De WaeleEric Hoste

A1 Journal Article in EXPERT OPINION ON PHARMACOTHERAPY

Current surgical management of acute pancreatitis

T DUGERNIERJan De WaelePF LATERRE

A1 Journal Article in ACTA CHIRURGICA BELGICA

Decompressive laparotomy for abdominal compartment syndrome - a critical analysis

Jan De WaeleEric HosteMLNG MALBRAIN

A1 Journal Article in CRITICAL CARE

Effect of fluconazole consumption on long-term trends in candidal ecology

Stijn BlotRomy JanssensGeert ClaeysEric HosteFranky BuyleJan De WaeleRenaat PelemanDirk VogelaersKoenraad Vandewoude

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Modulation of seizure threshold by vagus nerve stimulation in an animal model for motor seizures

Veerle De HerdtJan De WaeleJeroen Van AkenKristl VonckJean DelbekeRobrecht RaedtWytse WadmanPaul Boon

Outcome following severe burn injuries in Belgium

Nele BrusselaersEric HosteStan MonstreyKirsten ColpaertJan De WaeleKoenraad VandewoudeCynthia LafaireJean PirsonJean-Philippe FauvilleMichael Casaer et al.

Propofol infusion syndrome in a patient with sepsis

Jan De WaeleEric Hoste

A1 Journal Article in ANAESTHESIA AND INTENSIVE CARE

Results from the international conference of experts on intra-abdominal hypertension and abdominal compartment syndrome. I. Definitions

MLNG MALBRAINML CHEATHAMA KIRKPATRICKM SUGRUEM PARRJan De WaeleZ BALOGHA LEPPANIEMIC OLVERAR IVATURY et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Saline volume in transvesical intra-abdominal pressure measurement: enough is enough

Jan De WaelePIETER PLETINCKXStijn BlotEric Hoste

A1 Journal Article in INTENSIVE CARE MEDICINE

The effect of neuromuscular blockers on intraabdominal pressure.

Jan De WaeleI DELAETEric HosteE VERHOLENStijn Blot

Thrombocytopenia as a marker of poor outcome in ICU patients with severe BSI.

Dominique VandijckStijn BlotJan De WaeleEric HosteKoenraad VandewoudeJohan Decruyenaere

2005

Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections

Stijn BlotPieter DepuydtLieven AnnemansDominique BenoitEric HosteJan De WaeleJohan DecruyenaereDirk VogelaersFrancis ColardynKoenraad Vandewoude

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Colonization status and appropriate antibiotic therapy for nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in an intensive care unit

Stijn BlotPieter DepuydtDirk VogelaersJohan DecruyenaereJan De WaeleEric HosteRenaat PelemanGeert ClaeysGerda VerschraegenFrancis Colardyn et al.

A1 Journal Article in INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Critical issues in the clinical management of complicated intra-abdominal infections

Stijn BlotJan De Waele

A1 Journal Article in DRUGS

Fluid vs. air for semicontinuous intra-abdominal pressure measurements using a compliance catheter

Jan De WaeleERIK BILLIETEric HosteStijn BlotFrancis Colardyn

A1 Journal Article in INTENSIVE CARE MEDICINE

Influence of matching for exposure time on estimates of attributable mortality caused by nosocomial bacteremia in critically ill patients

Stijn BlotDirk De BacquerEric HostePieter DepuydtKoenraad VandewoudeJan De WaeleDominique BenoitJOHAN DE SCHUIJMERFrancis ColardynDirk Vogelaers

A1 Journal Article in INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Intra-abdominal hypertension in patients with severe acute pancreatitis

Jan De WaeleEric HosteStijn BlotJohan DecruyenaereFrancis Colardyn

A1 Journal Article in CRITICAL CARE

Life saving abdominal decompression in a patient with severe acute pancreatitis

Jan De WaeleUwe Hesse

A1 Journal Article in ACTA CHIRURGICA BELGICA

Outcome and changes over time in survival following severe burns from 1985 to 2004

Nele BrusselaersEric HosteStan MonstreyKirsten ColpaertJan De WaeleKoenraad VandewoudeStijn Blot

A1 Journal Article in INTENSIVE CARE MEDICINE

Outcome following burns from 1985 to 2004 in the centre for severely burned patients, Ghent University Hosptial, Belgium

Nele BrusselaersEric HosteKoenraad VandewoudeJan De WaeleKirsten ColpaertStan MonstreyStijn Blot

Phenytoin intoxication in critically ill patients

Gert De SchoenmakereJan De WaeleWim TerrynMieke DeweweireAlain VerstraeteEric HosteSylvie RotteyNorbert LameireFrancis Colardyn

A1 Journal Article in AMERICAN JOURNAL OF KIDNEY DISEASES

Physiologic consequences of acute renal failure on the critically ill

Eric HosteJan De Waele

A1 Journal Article in CRITICAL CARE CLINICS

Sodium bicarbonate versus THAM in ICU patients with mild metabolic acidosis

Eric HosteKirsten ColpaertRaymond VanholderNorbert LameireJan De WaeleStijn BlotFrancis Colardyn

A1 Journal Article in JOURNAL OF NEPHROLOGY

The use of early CT scan in predicting outcome in acute pancreatitis: A pilot study.

Jan De WaeleStijn BlotEric HosteLouke DelruePhilippe Duyck

Would patients with more subtle signs of coagulopathy have benefited from treatment with activated protein C?

Dominique BenoitPieter DepuydtJan De WaeleEric HosteME COLPAERTVANESSA VAN HENDEJohan Decruyenaere

A1 Journal Article in CRITICAL CARE MEDICINE

2004

Acute respiratory effects of the upright position in ards patients

Jan De WaeleKirsten ColpaertSandra OeyenJohan DecruyenaereJan PoelaertCarl Roosens

Attributable mortality of noscomial candidemia caused by Candida non-albicans spp in critically ill patients

Stijn BlotJan De WaeleKoenraad VandewoudeDirk De BacquerEric HosteJ DESCHUIJMERJohan DecruyenaereFrancis Colardyn

Bloodstream infections after surgery for severe acute pancreatitis

Jan De WaeleStijn BlotFrancis Colardyn

A1 Journal Article in PANCREAS

Emergence of antibiotic resistance in infected pancreatic necrosis

Jan De WaeleDirk VogelaersEric HosteStijn BlotFrancis Colardyn

A1 Journal Article in ARCHIVES OF SURGERY

High infection rates in patients with severe acute necrotizing pancreatitis

Jan De WaeleStijn BlotDirk VogelaersFrancis Colardyn

A1 Journal Article in INTENSIVE CARE MEDICINE

Infectious complications of acute pancreatitis

Jan De WaeleDirk VogelaersJohan DecruyenaereMartine De VosFrancis Colardyn

A1 Journal Article in ACTA CLINICA BELGICA

Organ dysfunction as a risk factor for early severe acute pancreatitis

Jan De WaeleStijn BlotFrancis Colardyn

A1 Journal Article in WORLD JOURNAL OF GASTROENTEROLOGY

Perioperative factors determine outcome after surgery for severe acute pancreatitis

Jan De WaeleEric HosteStijn BlotUwe HessePiet PattynBernard de HemptinneJohan DecruyenaereDirk VogelaersFrancis Colardyn

A1 Journal Article in CRITICAL CARE

The assumed problem of air bubbles in the tubing during intra-abdominal pressure measurement

Jan De WaeleERIK BILLIETEric HosteFrancis Colardyn

A1 Journal Article in INTENSIVE CARE MEDICINE

2003

A role for muscle relaxation in patients with abdominal compartment syndrome?

Jan De WaeleDominique BenoitEric HosteFrancis Colardyn

A1 Journal Article in INTENSIVE CARE MEDICINE

Absence of excess mortality in critically ill patients with nosocomial Escherichia coli bacteremia

Stijn BlotKoenraad VandewoudeEric HosteJan De WaeleKathleen KintFanny RosiersDirk VogelaersFrancis Colardyn

A1 Journal Article in INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Adrenal insufficiency in severe acute pancreatitis

Jan De WaeleEric HosteJohan DecruyenaereFrancis Colardyn

A1 Journal Article in PANCREAS

Fungal infections in patients with severe acute pancreatitis and the use of prophylactic therapy

Jan De WaeleDirk VogelaersStijn BlotFrancis Colardyn

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Impact of bloodstream infection on the outcome of patients with acute renal failure

Eric HosteStijn BlotJan De WaeleKirsten ColpaertSandra OeyenJohan DecruyenaereFrancis Colardyn

The impact of timing of surgical intervention on survival in patients with severe acute pancreatitis

Jan De WaeleJohan DecruyenaereEric HosteStijn BlotUwe HesseKirsten ColpaertFrancis Colardyn

The use of the activated clotting time for monitoring heparin therapy in critically ill patients

Jan De WaeleS CAUWENBERGHEEric HosteDominique BenoitFrancis Colardyn

A1 Journal Article in INTENSIVE CARE MEDICINE

The use of the activated clotting time for monitoring heparin therapy in critically ill patients (vol 29, pg 325, 2003)

Jan De WaeleS VAN CAUWENBERGHEEric HosteDominique BenoitFrancis Colardyn

Translumbar extraperitoneal decompression for abdominal compartment syndrome after endovascular treatment of a ruptured AAA

Isabelle Van HerzeeleJan De WaeleFrank Vermassen

A1 Journal Article in JOURNAL OF ENDOVASCULAR THERAPY

2002

Blunt cardiac injury in patients with isolated sternal fractures: the importance of fracture grading.

Jan De WaelePaul CalleLode BlondeelFrank Vermassen

A2 Journal Article in EUROPEAN JOURNAL OF TRAUMA

Coagulopathy, hypothermia and acidosis in trauma patients : the rationale for damage control surgery

Jan De WaeleFrank Vermassen

A1 Journal Article in ACTA CHIRURGICA BELGICA

Diagnosis of myocardial perforation by a Greenfield filter made by transesophageal echocardiography

Jan De WaeleMichel De PauwYves Van BelleghemGuido Van Nooten

A1 Journal Article in JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY

Severe complications after nonoperative treatment of traumatic aortic rupture

Stephen J VerbekeJan De WaeleUwe HesseFrank VermassenJoseph De Roose

A1 Journal Article in JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Typhlitis in an immunocompromised patient.

S DE LAEREJan De WaeleB HEMPTINNE

A1 Journal Article in ACTA CHIRURGICA BELGICA

2001

Bronchial rupture after direct chest trauma in a child

Jan De WaeleFrank VermassenJ De Roose

A1 Journal Article in ACTA CHIRURGICA BELGICA

Clamp and sew repair for traumatic aortic rupture

S VerbekeJan De WaeleP WolterFrank VermassenCaren RandonJoseph Deroose

Efficacy and side effects of a single dose of trometamol or bicarbonate as a buffer in patients with mild acidosis

KE COLPAERTEric HosteJ NolletS OeyenP DepuydtJan De WaeleJohan DecruyenaereKoenraad MonsieursE OsipowskaFrancis Colardyn

Limy bile and laparoscopic cholecystectomy

T OnghenaJan De WaeleL VereeckenC Van Loon

A1 Journal Article in ACTA CHIRURGICA BELGICA

Thrombosis of an aneurysm of the basilic vein: upper extremity venous aneurysm

Jan De WaelePaul CalleFrank Vermassen

A1 Journal Article in ACTA CHIRURGICA BELGICA

2000

Postoperative lavage and on demand surgical intervention in the treatment of acute necrotizing pancreatitis

Jan De WaeleUwe HessePiet PattynJohan DecruyenaereBernard de Hemptinne

A1 Journal Article in ACTA CHIRURGICA BELGICA

1999

Splenic herniation causing massive haemothorax after blunt trauma

Jan De WaeleFrank Vermassen

A1 Journal Article in JOURNAL OF ACCIDENT & EMERGENCY MEDICINE

Surgeons and the Internet

Wim CeelenJan De Waele

A1 Journal Article in EUROPEAN JOURNAL OF SURGERY

1997

Non-operative management of a splenic laceration in a patient with the Proteus syndrome

Wim CeelenJan De WaeleMarc KunnenBernard de Hemptinne

A1 Journal Article in JOURNAL OF ACCIDENT & EMERGENCY MEDICINE

1996

Surgical management of diverticulitis : a two year retrospective study

Piet PattynJan De WaeleS CleymanUwe HesseBernard de Hemptinne

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA