Research Explorer

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Researcher

Jamie De Baere

Awards & Distinctions

4 Results

2025

Thioamides adjacent to the ionizable amine headgroup in ionizable lipids reduce the pKa of lipid nanoparticles and enhance mRNA transfection efficiency in vitro and in vivo

Yong ChenEmily De LombaerdeAimee-Rose Bugler-LambZifu ZhongMartijn SchuijsClaudia Mariela Brenis GómezJamie De BaereMark GontsarikHeleen LauwersKim Deswarte et al.

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2024

Amplification of protein expression by self-amplifying mRNA delivered in lipid nanoparticles containing a β-aminoester ionizable lipid correlates with reduced innate immune activation

Emily De LombaerdeXiaole CuiYong ChenZifu ZhongJulie DeckersGiulia MencarelliLisa OpsomerHaixiu WangJamie De BaereStefan Lienenklaus et al.

A1 Journal Article in ACS NANO

High-throughput single-cell screening of viable hybridomas and patient-derived antibody-secreting cells using punchable microwells

Kaat RubbenAnn-Sophie Vander PlaetsenRuben AlmeyOlivier TytgatKoen DeserrannoJamie De BaereDelphine AcarPhilip MeulemanDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY

Lysosomal trafficking and degradation of extracellular proteins via multivalent small molecule ligand display on dextran scaffolds

Benoit LouageDemi DefreyneHeleen LauwersJamie De BaereAnnemiek UvynHaixia PengYong ChenBruno De Geest

A1 Journal Article in BIOMACROMOLECULES