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Researcher
Jamie De Baere
Profile
Projects
Publications
Activities
Awards & Distinctions
4
Results
2025
Thioamides adjacent to the ionizable amine headgroup in ionizable lipids reduce the pKa of lipid nanoparticles and enhance mRNA transfection efficiency in vitro and in vivo
Yong Chen
Emily De Lombaerde
Aimee-Rose Bugler-Lamb
Zifu Zhong
Martijn Schuijs
Claudia Mariela Brenis Gómez
Jamie De Baere
Mark Gontsarik
Heleen Lauwers
Kim Deswarte
et al.
A1
Journal Article
in
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2025
2024
Amplification of protein expression by self-amplifying mRNA delivered in lipid nanoparticles containing a β-aminoester ionizable lipid correlates with reduced innate immune activation
Emily De Lombaerde
Xiaole Cui
Yong Chen
Zifu Zhong
Julie Deckers
Giulia Mencarelli
Lisa Opsomer
Haixiu Wang
Jamie De Baere
Stefan Lienenklaus
et al.
A1
Journal Article
in
ACS NANO
2024
High-throughput single-cell screening of viable hybridomas and patient-derived antibody-secreting cells using punchable microwells
Kaat Rubben
Ann-Sophie Vander Plaetsen
Ruben Almey
Olivier Tytgat
Koen Deserranno
Jamie De Baere
Delphine Acar
Philip Meuleman
Dieter Deforce
Filip Van Nieuwerburgh
A1
Journal Article
in
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
2024
Lysosomal trafficking and degradation of extracellular proteins via multivalent small molecule ligand display on dextran scaffolds
Benoit Louage
Demi Defreyne
Heleen Lauwers
Jamie De Baere
Annemiek Uvyn
Haixia Peng
Yong Chen
Bruno De Geest
A1
Journal Article
in
BIOMACROMOLECULES
2024