Research Explorer

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Researcher

Jacob Pollier

Awards & Distinctions

63 Results

2023

The saponin bomb : a nucleolar-localized β‐glucosidase hydrolyzes triterpene saponins in Medicago truncatula

Elia LacchiniMarie-Laure ErffelinckJan MertensShirley MarcouFranciso Javier Molina HidalgoOren TzfadiaJhon Jairo Venegas MolinaPablo D. CárdenasJacob PollierAldo Tava et al.

A1 Journal Article in NEW PHYTOLOGIST

2022

Overexpression of the scopoletin biosynthetic pathway enhances lignocellulosic biomass processing

Lennart HoengenaertMarlies WoutersHoon KimBarbara De MeesterKris MorreelSteven VandersyppeJacob PollierSandrien DesmetGeert GoeminneJohn Ralph et al.

A1 Journal Article in SCIENCE ADVANCES

The basic helix-loop-helix transcription factors MYC1 and MYC2 have a dual role in the regulation of constitutive and stress-inducible specialized metabolism in tomato

Gwen SwinnenMargaux De MeyerJacob PollierFranciso Javier Molina HidalgoEvi CeulemansJhon Jairo Venegas MolinaLiesbeth De MildePatricia Fernandez CalvoMily RonLaurens Pauwels et al.

A1 Journal Article in NEW PHYTOLOGIST

2021

An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara

Lemeng DongAldo AlmeidaJacob PollierBekzod KhakimovJean-Etienne BassardKarel MiettinenDan StærkRahimi MehranCarl Erik OlsenMohammed Saddik Motawia et al.

A1 Journal Article in MOLECULAR BIOLOGY AND EVOLUTION

Dissecting cholesterol and phytosterol biosynthesis via mutants and inhibitors

Kjell De VrieseJacob PollierAlain GoossensTom BeeckmanSteffen Vanneste

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

Modulation of Arabidopsis root growth by specialized triterpenes

Yuechen BaiPatricia Fernandez CalvoAndrés Ritter TraubAncheng C. HuangStefania MoralesKeylla BicalhoMichal KaradyLaurens PauwelsDieter BuystMaria Njo et al.

A1 Journal Article in NEW PHYTOLOGIST

Rewired phenolic metabolism and improved saccharification efficiency of a Zea mays cinnamyl alcohol dehydrogenase 2 (zmcad2) mutant

Xinyu LiuRebecca Van AckerWannes VoorendAndreas PallidisGeert GoeminneJacob PollierKris MorreelHoon KimHilde MuylleMickael Bosio et al.

A1 Journal Article in PLANT JOURNAL

Seedling developmental defects upon blocking CINNAMATE‐4‐HYDROXYLASE are caused by perturbations in auxin transport

Ilias El HouariCaroline Van BeirsHelena ArentsHuibin HanAlexandra Alvarenga ChanocaDavy OpdenackerJacob PollierVeronique StormeWard SteenackersMussa Quareshy et al.

A1 Journal Article in NEW PHYTOLOGIST

Subfunctionalization of paralog transcription factors contributes to regulation of alkaloid pathway branch choice in Catharanthus roseus

Maite Colinas MartinezJacob PollierDries VaneechoutteDeniz MalatFabian SchweizerLiesbeth De MildeRebecca De ClercqJoana G. GuedesTeresa Martínez-CortésFrancisco Hidalgo et al.

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

The heat shock protein 40-type chaperone MASH supports the endoplasmic reticulum-associated degradation E3 ubiquitin ligase MAKIBISHI1 in Medicago truncatula

Marie-Laure ErffelinckBianca RibeiroLore GryffroyAvanish Kumar RaiJacob PollierAlain Goossens

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

2020

A seed-specific regulator of triterpene saponin biosynthesis in Medicago truncatula

Bianca RibeiroElia LacchiniKeylla BicalhoJan MertensPhilipp ArendtRobin Vanden BosscheGabriela CalegarioLore GryffroyEvi CeulemansJulia Buitink et al.

A1 Journal Article in PLANT CELL

Tailoring poplar lignin without yield penalty by combining a null and haploinsufficient CINNAMOYL-CoA REDUCTASE2 allele

Barbara De MeesterBárbara Loreto Madariaga CalderónLisanne de VriesJacob PollierGeert GoeminneJan Van DoorsselaereMingjie ChenJohn RalphRuben VanholmeWout Boerjan

A1 Journal Article in NATURE COMMUNICATIONS

2019

A widespread alternative squalene epoxidase participates in eukaryote steroid biosynthesis

Jacob PollierEmmelien VancaesterUnnikrishnan KuzhiumparambilClaudia E. VickersKlaas VandepoeleAlain GoossensMichele Fabris

A1 Journal Article in NATURE MICROBIOLOGY

CYP712K4 catalyzes the C-29 oxidation of friedelin in the Maytenus ilicifolia quinone methide triterpenoid biosynthesis pathway

Keylla BicalhoMariana M. SantoniPhilipp ArendtCleslei F. ZanelliMaysa FurlanAlain GoossensJacob Pollier

A1 Journal Article in PLANT AND CELL PHYSIOLOGY

Integrated metabolomics identifies CYP72A67 and CYP72A68 oxidases in the biosynthesis of Medicago truncatula oleanate sapogenins

Vered TzinJohn H SnyderDong Sik YangDavid V HuhmanBonnie S WatsonStacy N AllenYuhong TangKarel MiettinenPhilipp ArendtJacob Pollier et al.

A1 Journal Article in METABOLOMICS

Regulation of triterpene saponin biosynthesis in Medicago truncatula

Bianca RibeiroAlain GoossensJacob Pollier

The MYB transcription factor Emission of Methyl Anthranilate 1 stimulates emission of methyl anthranilate from Medicago truncatula hairy roots

Jacob PollierNathan De GeyterTessa MosesBenoît BoachonJosé Manuel Franco ZorrillaYuechen BaiElia LacchiniAzra GholamiRobin Vanden BosscheDanièle Werck‐Reichhart et al.

A1 Journal Article in PLANT JOURNAL

Triterpenoid biosynthesis and its regulation in Arabidopsis thaliana

Yuechen BaiAlain GoossensJacob PollierPatricia Fernández Calvo

2018

A user-friendly platform for yeast two-hybrid library screening using next generation sequencing

Marie-Laure ErffelinckBianca RibeiroMaría PerassoloLaurens PauwelsJacob PollierVeronique StormeAlain Goossens

A1 Journal Article in PLOS ONE

An engineered combinatorial module of transcription factors boosts production of monoterpenoid indole alkaloids in Catharanthus roseus

Fabian SchweizerMaite Colinas MartinezJacob PollierAlex Van MoerkerckeRobin Vanden BosscheRebecca De ClercqAlain Goossens

A1 Journal Article in METABOLIC ENGINEERING

Co-expression of squalene epoxidases with triterpene cyclases boosts production of triterpenoids in plants and yeast

Lemeng DongJacob PollierJean-Etienne BassardGeorgios NtallasAldo AlmeidaEleni LazaridiBekzod KhakimovPhilipp ArendtLouisi Souza de OliveiraFrederic Lota et al.

A1 Journal Article in METABOLIC ENGINEERING

The TriForC database : a comprehensive up-to-date resource of plant triterpene biosynthesis

Karel MiettinenSabrina IñigoLukasz KreftJacob PollierChristof De BoAlexander BotzkiFrederik CoppensSoren BakAlain Goossens

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2017

Abscisic acid as pathogen effector and immune regulator

Laurens LievensJacob PollierAlain GoossensRudi BeyaertJens Staal

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

An endoplasmic reticulum-engineered yeast platform for overproduction of triterpenoids

Philipp ArendtKarel MiettinenJacob PollierRiet De RyckeNico CallewaertAlain Goossens

A1 Journal Article in METABOLIC ENGINEERING

Identification of iridoid glucoside transporters in Catharanthus roseus

Bo LarsenVictoria L FullerJacob PollierAlex Van MoerkerckeFabian SchweizerRichard PayneMaite Colinas MartinezSarah E O'ConnorAlain GoossensBarbara A Halkier

A1 Journal Article in PLANT AND CELL PHYSIOLOGY

Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism

Prashant D. SonawaneJacob PollierSayantan PandaJedrzej SzymanskiHassan MassalhaMeital YonaTamar UngerSergey MalitskyPhilipp ArendtLaurens Pauwels et al.

A1 Journal Article in NATURE PLANTS

Strobilurins as growth-promoting compounds : how Stroby regulates Arabidopsis leaf growth

Judith Van DingenenChrystalla AntoniouPanagiota FilippouJacob PollierNathalie Gonzalez SanchezStijn DhondtAlain GoossensVasileios FotopoulosDirk Inzé

A1 Journal Article in PLANT CELL AND ENVIRONMENT

The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis

Karel MiettinenJacob PollierDieter BuystPhilipp ArendtRené CsukSven SommerwerkTessa MosesJan MertensPrashant D SonawaneLaurens Pauwels et al.

A1 Journal Article in NATURE COMMUNICATIONS

2016

Clade IVa basic helix–loop–helix transcription factors form part of a conserved jasmonate signaling circuit for the regulation of bioactive plant terpenoid biosynthesis

Jan MertensAlex Van MoerkerckeRobin Vanden BosscheJacob PollierAlain Goossens

A1 Journal Article in PLANT AND CELL PHYSIOLOGY

Cloning and functional characterization of cycloartenol synthase from the red seaweed Laurencia dendroidea

Gabriela CalegarioJacob PollierPhilipp ArendtLouisi Souza de OliveiraCristiane ThompsonAngélica Ribeiro SoaresRenato Crespo PereiraAlain GoossensFabiano L Thompson

A1 Journal Article in PLOS ONE

GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway

Pablo D CárdenasPrashant D SonawaneJacob PollierRobin Vanden BosscheVeena DewanganEfrat WeithornLior TalSagit MeirIlana RogachevSergey Malitsky et al.

A1 Journal Article in NATURE COMMUNICATIONS

Hypersensitivity of Arabidopsis TAXIMIN1 overexpression lines to light stress is correlated with decreased sinapoyl malate abundance and countered by the antibiotic cefotaxime

Janine CollingJacob PollierRobin Vanden BosscheNokwanda Pearl MakungaLaurens PauwelsAlain Goossens

A1 Journal Article in PLANT SIGNALING & BEHAVIOR

Isolation of protein complexes from the model legume Medicago truncatula by tandem affinity purification in hairy root cultures

Jonas GoossensNathan De GeyterAlan WaltonDominique EeckhoutJan MertensJacob PollierJennifer Liliana Fiallos JuradoAnnick De KeyserRebecca De ClercqJelle Van Leene et al.

A1 Journal Article in PLANT JOURNAL

Saponin determination, expression analysis and functional characterization of saponin biosynthetic genes in Chenopodium quinoa leaves

Jennifer Fiallos-JuradoJacob PollierTessa MosesPhilipp ArendtNoelia Barriga-MedinaEduardo MorilloiVenancio ArahanaMaria de Lourdes TorresAlain GoossensAntonio Leon-Reyes

A1 Journal Article in PLANT SCIENCE

Synthetic biology for production of natural and new-to-nature terpenoids in photosynthetic organisms

Philipp ArendtJacob PollierNico CallewaertAlain Goossens

A1 Journal Article in PLANT JOURNAL

The bHLH transcription factors TSAR1 and TSAR2 regulate triterpene saponin biosynthesis in Medicago truncatula

Jan MertensJacob PollierRobin Vanden BosscheIrene Lopez-VidrieroJosé Manuel Franco-ZorrillaAlain Goossens

A1 Journal Article in PLANT PHYSIOLOGY

2015

Iridoid synthase activity is common among the plant progesterone 5β-reductase family

Jennifer MunkertJacob PollierKarel MiettinenAlex Van MoerkerckeRichard PayneFrieder Müller-UriVincent BurlatSarah E O'ConnorJohan MemelinkWolfgang Kreis et al.

A1 Journal Article in MOLECULAR PLANT

OSC2 and CYP716A14v2 catalyze the biosynthesis of triterpenoids for the cuticle of aerial organs of Artemisia annua

Tessa MosesJacob PollierQian ShenSandra SoetaertJames ReedMarie-Laure ErffelinckFilip Van NieuwerburghRobin Vanden BosscheAnne OsbournJohan M Thevelein et al.

A1 Journal Article in PLANT CELL

The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus

Alex Van MoerkerckePriscille SteensmaFabian SchweizerJacob PollierIvo GariboldiRichard PayneRobin Vanden BosscheKarel MiettinenJaviera EspozPurin Candra Purnama et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unravelling the triterpenoid saponin biosynthesis of the African shrub Maesa lanceolata

Tessa MosesJacob PollierAhmad FaizalSandra ApersLuc PietersJohan M TheveleinDanny GeelenAlain Goossens

A1 Journal Article in MOLECULAR PLANT

2014

Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16α hydroxylase from Bupleurum falcatum

Tessa MosesJacob PollierLorena AlmagroDieter BuystMarc Van MontaguMaría A PedreñoJosé MartinsJohan M TheveleinAlain Goossens

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative analysis of CYP93E proteins for improved microbial synthesis of plant triterpenoids

Tessa MosesJohan M TheveleinAlain GoossensJacob Pollier

A1 Journal Article in PHYTOCHEMISTRY

Natural product biosynthesis in Medicago species

Azra GholamiNathan De GeyterJacob PollierSofie GoormachtigAlain Goossens

A1 Journal Article in NATURAL PRODUCT REPORTS

Selection and validation of reference genes for transcript normalization in gene expression studies in Catharanthus roseus

Jacob PollierRobin Vanden BosscheHeiko RischerAlain Goossens

A1 Journal Article in PLANT PHYSIOLOGY AND BIOCHEMISTRY

Taximin, a conserved plant-specific peptide is involved in the modulation of plant-specialized metabolism

Miriam OnrubiaJacob PollierRobin Vanden BosscheMarc GoethalsKris GevaertElisabet MoyanoHeriberto Vidal-LimonRosa M CusidóJavier PalazónAlain Goossens

A1 Journal Article in PLANT BIOTECHNOLOGY JOURNAL

The seco-iridoid pathway from Catharanthus roseus

Karel MiettinenLemeng DongNicolas NavrotThomas SchneiderVincent BurlatJacob PollierLotte WoittiezSander van der KrolRaphael LuganTina Ilc et al.

A1 Journal Article in NATURE COMMUNICATIONS

Tracking the sterol biosynthesis pathway of the diatom Phaeodactylum tricornutum

Michele FabrisMichiel MatthijsSophie CarbonelleTessa MosesJacob PollierRenaat DassevilleGino BaartWim VyvermanAlain Goossens

A1 Journal Article in NEW PHYTOLOGIST

2013

Analysis of RNA-Seq data with TopHat and Cufflinks for genome-wide expression analysis of jasmonate-treated plants and plant cell cultures

Jacob PollierStephane RombautsAlain Goossens

Bookchapter in Jasmonate signaling : methods and protocols

Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biology in vivo and in vitro

Tessa MosesJacob PollierJohan M TheveleinAlain Goossens

A1 Journal Article in NEW PHYTOLOGIST

CathaCyc, a metabolic pathway database built from Catharanthus roseus RNA-Seq data

Alex Van MoerkerckeMichele FabrisJacob PollierGino BaartStephane RombautsGhulam HasnainHeiko RischerJohan MemelinkKirsi-Marja Oksman-CaldenteyAlain Goossens

A1 Journal Article in PLANT AND CELL PHYSIOLOGY

Metabolite profiling of plant tissues by liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry

Jacob PollierAlain Goossens

Bookchapter in Jasmonate signaling : methods and protocols

The protein quality control system manages plant defence compound synthesis

Jacob PollierTessa MosesMiguel Gonzalez GuzmanNathan De GeyterSaskia LippensRobin Vanden BosschePeter MarhavyAnna KremerKris MorreelChris Guerin et al.

A1 Journal Article in NATURE

cDNA-AFLP-based transcript profiling for genome-wide expression analysis of jasmonate-treated plants and plant cultures

Janine CollingJacob PollierNokwanda P MakungaAlain Goossens

Bookchapter in Jasmonate signaling : methods and protocols

2012

Characterization of a RABE (Ras gene from rat brain E) GTPase expressed during morphogenesis in the unicellular green alga Micrasterias denticulata (Zygnematophyceae, Streptophyta)

Katrijn VannerumRiet De RyckeJacob PollierAlain GoossensDirk InzéWim Vyverman

A1 Journal Article in JOURNAL OF PHYCOLOGY

Jacob PollierAlain Goossens

A1 Journal Article in PHYTOCHEMISTRY

2011

An integrated PCR colony hybridization approach to screen cDNA libraries for full-length coding sequences

Jacob PollierMiguel Gonzalez GuzmanWilson Ardiles DiazDanny GeelenAlain Goossens

A1 Journal Article in PLOS ONE

Combinatorial biochemistry of triterpene saponins in plants

Jacob PollierAlain Goossens

Combinatorial biosynthesis in plants: a (p)review on its potential and future exploitation

Jacob PollierTessa MosesAlain Goossens

A1 Journal Article in NATURAL PRODUCT REPORTS

Dissection of the phytohormonal regulation of trichome formation and biosynthesis of the antimalarial compound artemisinin in Artemisia annua plants

Lies MaesFilip Van NieuwerburghYansheng ZhangDarwin W ReedJacob PollierSofie Vande CasteeleDirk InzéPatrick S CovelloDieter DeforceAlain Goossens

A1 Journal Article in NEW PHYTOLOGIST

Metabolite profiling of Triterpene Saponins in medicago truncatula hairy roots by liquid chromatography fourier transform Ion Cyclotron resonance mass spectrometry

Jacob PollierKris MorreelDanny GeelenAlain Goossens

A1 Journal Article in JOURNAL OF NATURAL PRODUCTS

Transcriptional analysis of cell growth and morphogenesis in the unicellular green alga Micrasterias (Streptophyta), with emphasis on the role of expansin

Katrijn VannerumMarie HuysmanRiet De RyckeMarnik VuylstekeFrédérik LeliaertJacob PollierUrsula Lutz-MeindlJeroen GillardLieven De VeylderAlain Goossens et al.

A1 Journal Article in BMC PLANT BIOLOGY

2009

Rapid quantification of 14 saponins of Maesa lanceolata by UPLC-MS/MS

K FoubertF CuykenM TheunisJacob PollierMiguel Gonzalez GuzmanEllen LambertDanny GeelenAlain GoossensA VlietinckL Pieters et al.

2007

Determination of saponins in Maesa lanceolata by LC-UV: development and validation

Mart HBL TheunisKenn FoubertJacob PollierMiguel Gonzalez GuzmanAlain GoossensArnold J VlietinckLuc AC PietersSandra Apers

A1 Journal Article in PHYTOCHEMISTRY