Research Explorer

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Researcher

Isabela Roxana Birs

Publications & Research Data

Awards & Distinctions

90 Results

2026

Pharmacokinetic modelling during long-term anesthesia: minimizing the gap

Amani Rayene YninebErhan YumukDana CopotGhada Ben OthmanHamed FarbakhshIsabela Roxana BirsRobain De KeyserSamir LadaciCristina MuresanMartine Neckebroek et al.

U Journal Article in JOURNAL OF ADVANCED RESEARCH

2025

Integrated solution combining low-frequency forced oscillation technique and continuous equivital sensor monitoring for assessment of non-invasive ambulatory respiratory mechanics

Ghada Ben OthmanAmani Rayene YninebErhan YumukHamed FarbakhshCristina MuresanIsabela Roxana BirsAlexandra De RaeveCosmin CopotClara-Mihaela IonescuDana Copot

A1 Journal Article in APPLIED SCIENCES-BASEL

Modeling drug retention as memory effects in obese patients using fractional and augmented models

Amani Rayene YninebErhan YumukDana CopotBora AyvazBouchra KhoumeriGhada Ben OthmanMarcian n D. MihaiIsabela Roxana BirsCristina I. MuresanClara Ionescu

A1 Journal Article in SCIENTIFIC REPORTS

Online and personalised control of the Depth of hypnosis during induction using fractional order PID

Marcian MihaiIsabela Roxana BirsErwin HegedusAmani Rayene YninebDana CopotRobain De KeyserClara IonescuSamir LadaciCristina I. MuresanMartine Neckebroek

A1 Journal Article in JOURNAL OF ADVANCED RESEARCH

Personalised fractional-order autotuner for the maintenance phase of anaesthesia using sine-tests

Marcian D. MihaiIsabela Roxana BirsNicoleta E. BadauErwin T. HegedusAmani Rayene YninebCristina I. Muresan

A1 Journal Article in FRACTAL AND FRACTIONAL

Revisiting the impulse response creates an improved PID autotuner

Robain De KeyserIsabela Roxana BirsCristina MuresanClara Ionescu

A1 Journal Article in SCIENTIFIC REPORTS

The role of fractional calculus in modern optimization : a survey of algorithms, applications, and open challenges

Edson FernandezVictor HuilcapiIsabela Roxana BirsRicardo Cajo

A1 Journal Article in MATHEMATICS

Validation of a short relay test PID autotuner on a nonlinear process with stochastic disturbances*

Isabela Roxana BirsCatalina RizelMarcian MihaiCristina MuresanRobain De Keyser

2024

A compact fractional-order model for hypnosis in general anesthesia

Marcian MihaiIsabela Roxana BirsErwin HegedusDana CopotRobain De KeyserClara-Mihaela IonescuCristina MuresanMartine Neckebroek

A compartmental modelling framework for drug distribution in lean and obese patients in long-term general anesthesia

Amani Rayene YninebErhan YumukHamed FarbakhshGhada Ben OthmanDana CopotIsabela Roxana BirsCristina MuresanRobain De KeyserSamir LadaciClara-Mihaela Ionescu et al.

A decoupled fractional order control strategy to increase patient safety during anesthesia-hemodynamic interactions

Erwin HegedusMarcian D. MihaiIsabela Roxana BirsHamed FarbakhshErhan YumukDana CopotRobain De KeyserClara-Mihaela IonescuCristina Muresan

A fractional order impedance model for heterogeneous drug distribution in obese patients during general anesthesia

Amani Rayene YninebErhan YumukHamed FarbakhshGhada Ben OthmanDana CopotIsabela Roxana BirsCristina MuresanRobain De KeyserSamir LadaciClara-Mihaela Ionescu et al.

A novel decentralized-decoupled fractional-order control strategy for complete anesthesia-hemodynamic stabilization in patients undergoing surgical procedures

Erwin T. HegedusIsabela Roxana BirsClara-Mihaela IonescuCristina I. Muresan

A1 Journal Article in FRACTAL AND FRACTIONAL

A performant PID autotuner based on a short relay test

Robain De KeyserIsabela Roxana BirsClara-Mihaela IonescuCristina Muresan

A practical approach for transfer function estimation using short, transient process data

Robain De KeyserIsabela Roxana BirsCristina MuresanClara-Mihaela Ionescu

Analysis and preliminary results of a feedback-feedforward controller for depth of anesthesia

Erwin HegedusMarcian D. MihaiIsabela Roxana BirsHamed FarbakhshErhan YumukDana CopotEva Henrietta DulfRobain De KeyserClara-Mihaela IonescuCristina Muresan

Artificial intelligence-driven prognosis of respiratory mechanics : forecasting tissue hysteresivity using long short-term memory and continuous sensor data

Ghada Ben OthmanAmani Rayene YninebErhan YumukHamed FarbakhshCristina MuresanIsabela Roxana BirsAlexandra De RaeveCosmin CopotClara-Mihaela IonescuDana Copot

A1 Journal Article in SENSORS

Comparative analysis of pharmacokinetic-pharmacodynamic models for Propofol and Remifentanil using model predictive control

Amani Rayene YninebHamed FarbakhshGhada Ben OthmanYlva WahlquistIsabela Roxana BirsErhan YumukCristina MuresanRobain De KeyserDana CopotClara-Mihaela Ionescu et al.

Development, validation, and comparison of a novel nociception/anti-nociception monitor against two commercial monitors in general anesthesia

Clara-Mihaela IonescuDana CopotErhan YumukRobain De KeyserCristina MuresanIsabela Roxana BirsGhada Ben OthmanHamed FarbakhshAmani Rayene YninebMartine Neckebroek

A1 Journal Article in SENSORS

Enhancing pain level assessment in post-surgery patients using artificial intelligence algorithms

Ghada Ben OthmanErhan YumukDana CopotAmani Rayene YninebHamed FarbakhshIsabela Roxana BirsCristina MuresanRobain De KeyserInes ChihiClara-Mihaela Ionescu et al.

First-hand design of a fractional order PID for controlling the depth of hypnosis during induction

Marcian MihaiIsabela Roxana BirsErwin HegedusDana CopotMartine NeckebroekRobain De KeyserClara-Mihaela IonescuCristina Muresan

Fractional order PID control of propofol dosage and optimization in lean and obese patients

Amani Rayene YninebMarcian-David MIHAIErhan YumukGhada Ben OthmanHamed FarbakhshRobain De KeyserCristina MuresanIsabela Roxana BirsDana CopotClara-Mihaela Ionescu

Fractional-order modeling of the depth of analgesia as reference model for control purposes

Cristina MuresanErwin T. HegedüsMarcian D. MihaiGhada Ben OthmanIsabela Roxana BirsDana CopotEva Henrietta DulfRobain De KeyserClara-Mihaela IonescuMartine Neckebroek

A1 Journal Article in FRACTAL AND FRACTIONAL

Minimizing epistemic uncertainty for predictive control of general anesthesia

Clara-Mihaela IonescuRobain De KeyserDana CopotErhan YumukIsabela Roxana BirsErwin HegedusCristina MuresanMartine Neckebroek

PID control of data-driven patient response with fixed ratio co-administration of drugs for depth of hypnosis

Clara-Mihaela IonescuHamed FarbakhshCristina MuresanRobain De KeyserErhan YumukGhada Ben OthmanAmani Rayene YninebIsabela Roxana BirsDana CopotMartine Neckebroek

Uncertainty and Its Effect On Optimal Multidrug Control of Hemodynamic Variables

Teodora PopescuIsabela Roxana BirsGhada Ben OthmanErhan YumukMarcian MihaiErwin HegedusDana CopotRobain De KeyserClara-Mihaela IonescuCristina I. Muresan

2023

A novel toolbox for automatic design of fractional order PI controllers based on automatic system identification from step response data

Cristina I. MuresanIulia BunescuIsabela Roxana BirsRobain De Keyser

A1 Journal Article in MATHEMATICS

An advanced fractional order method for temperature control

Ricardo Alfredo Cajo DiazShiquan ZhaoIsabela Roxana BirsVictor EspinozaEdson Rodrigo Fernandez CornejoDouglas Antonio Plaza GuinglaGabriela Salcan-Reyes

A1 Journal Article in FRACTAL AND FRACTIONAL

Bioelectrical impedance analysis of thermal-induced cutaneous nociception

Mihaela GhitaIsabela Roxana BirsDana CopotCristina I. MuresanClara Ionescu

A1 Journal Article in BIOMEDICAL SIGNAL PROCESSING AND CONTROL

Context-aware control for quality improvement in liquid steel manufacturing

Isabela Roxana BirsCristina I. MuresanMircea SuscaVlad Mihai MihalyMihaela GhitaMaria GhitaRobain De KeyserClara-Mihaela Ionescu

Event-based fractional order MIMO control for hemodynamic stabilization during general anesthesia

Isabela Roxana BirsCristina MuresanMihaela GhitaMaria GhitaIoana NascuClara-Mihaela Ionescu

Model identification and control of electromagnetic actuation in continuous casting process with improved quality

Isabela Roxana BirsCristina MuresanDana CopotClara Ionescu

A1 Journal Article in IEEE-CAA JOURNAL OF AUTOMATICA SINICA

Model predictive control of hemodynamics during intravenous general anesthesia

Hamed FarbakhshErhan YumukGhada Ben OthmanRobain De KeyserDana CopotIsabela Roxana BirsClara-Mihaela Ionescu

Modelling of blood loss influence on propofol concentrations and anesthetic states in critical responses

Mihaela GhitaDana CopotIsabela Roxana BirsCristina MuresanMartine NeckebroekClara Ionescu

Parametric modeling and deep learning for enhancing pain assessment in postanesthesia

Mihaela GhitaIsabela Roxana BirsDana CopotCristina MuresanMartine NeckebroekClara-Mihaela Ionescu

A1 Journal Article in IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Reduced-order approximation of fractional-order controllers by keeping robust stability and robust performance

Vlad MihalyMircea SusçaIsabela Roxana BirsPetru Dobra

Robustness analysis of a fractional order control system for the hemodynamic variables in anesthetized patients

Erwin HegedusMihaela GhitaIsabela Roxana BirsDana CopotCristina I. Muresan

2022

A low-order approximation method for fractional order PID controllers

Isabela Roxana BirsCristina MuresanMaria GhitaClara-Mihaela IonescuRobain De Keyser

A review of recent developments in autotuning methods for fractional-order controllers

Cristina I. MuresanIsabela Roxana BirsClara-Mihaela IonescuEva H. DulfRobain De Keyser

A1 Journal Article in FRACTAL AND FRACTIONAL

A robust self-tuning PID-type control for time-varying process in the pharmaceutical industry

Mihaela GhitaDana CopotMaria GhitaIsabela Roxana BirsCristina MuresanRobain De KeyserClara-Mihaela Ionescu

Control of nonlinear mechatronic systems with context-dependent varying dynamics

Isabela Roxana BirsClara IonescuRobain De KeyserCosmin CopotCristina MuresanBogdan MuresanConstantin Florin Caruntu

Ergonomic and economic office light level control

Maria GhitaRicardo Alfredo Cajo DiazIsabela Roxana BirsDana CopotClara-Mihaela Ionescu

A1 Journal Article in ENERGIES

Fractional order models enabling control strategies based on material properties

Isabela Roxana BirsClara-Mihaela IonescuDana Copot

Fractional-order control strategy for anesthesia–hemodynamic stabilization in patients undergoing surgical procedures

Erwin T. HegedusIsabela Roxana BirsMihaela GhitaCristina I. Muresan

A1 Journal Article in FRACTAL AND FRACTIONAL

Fractional-order PI controller design based on reference-to-disturbance ratio

Cristina I. MuresanIsabela Roxana BirsDana CopotEva H. DulfClara-Mihaela Ionescu

A1 Journal Article in FRACTAL AND FRACTIONAL

Impedance spectroscopy sensing material properties for self-tuning ratio control in pharmaceutical industry

Mihaela GhitaIsabela Roxana BirsDana CopotIoana NascuClara-Mihaela Ionescu

A1 Journal Article in APPLIED SCIENCES-BASEL

Lumped parametric model for skin impedance data in patients with postoperative pain

Mihaela GhitaMaria GhitaDana CopotIsabela Roxana BirsCristina MuresanClara Ionescu

Optimizing radiotherapy with chemotherapy using PKPD modeling for lung cancer

Maria GhitaMihaela GhitaDana CopotIsabela Roxana BirsCristina MuresanClara-Mihaela Ionescu

Time-frequency varying tissue impedance properties from noxious stimulation protocols

Mihaela GhitaMaria GhitaDana CopotIsabela Roxana BirsRobain De KeyserClara-Mihaela Ionescu

Tuning guidelines and experimental comparisons of sine based auto-tuning methods for fractional order controllers

Isabela Roxana BirsCristina MuresanMarcian MihaiEva DulfRobain De Keyser

A1 Journal Article in IEEE ACCESS

Uncertainty minimization and feasibility study for managing the complex and interacting anesthesia-hemodynamic system

Mihaela GhitaDana CopotIsabela Roxana BirsCristina MuresanRobain De KeyserMartine NeckebroekMichel StruysClara-Mihaela Ionescu

Versatile solutions for the combine harvester header height control problem

Robain De KeyserIsabela Roxana BirsDana CopotMihaela GhitaCristina MuresanClara Ionescu

2021

A comparison between FOIMC and FOPI controllers for a submerged robot

Isabela Roxana BirsClara IonescuIoan NascuCristina Muresan

A review of recent advances in fractional-order sensing and filtering techniques

Cristina I. MuresanIsabela Roxana BirsEva H. DulfDana CopotLiviu Miclea

A1 Journal Article in SENSORS

An alternative design approach for Fractional Order Internal Model Controllers for time delay systems

C.I. MuresanIsabela Roxana BirsRobain De Keyser

A1 Journal Article in JOURNAL OF ADVANCED RESEARCH

An experimental approach towards motion modeling and control of a vehicle transiting a non-Newtonian environment

Isabela Roxana BirsCristina MuresanOvidiu ProdanSilviu FoleaClara-Mihaela Ionescu

A1 Journal Article in FRACTAL AND FRACTIONAL

Experimental comparison between discrete time and event-based PID controllers on a nonlinear process

Isabela Roxana BirsCristina MuresanIoan NascuRobain De Keyser

Fractional order control of the combined anaesthesia-hemodynamic system : a preliminary study

Erwin HegedusIsabela Roxana BirsCristina Muresan

2020

A non-Newtonian impedance measurement experimental framework: modeling and control inside blood-like environments—fractional-order modeling and control of a targeted drug delivery prototype with impedance measurement capabilities

Isabela Roxana BirsCristina Muresan

Bookchapter in Automated drug delivery in anesthesia

An energy-efficient context aware solution for environmental assessment

Isabela Roxana BirsCristina MuresanIoana NascuClara-Mihaela Ionescu

An event based implementation of a fractional order controller on a non-Newtonian transiting robot

Isabela Roxana BirsCristina MuresanClara-Mihaela Ionescu

Context aware control systems : an engineering applications perspective

Ricardo Alfredo Cajo DiazMihaela GhitaDana CopotIsabela Roxana BirsCristina MuresanClara-Mihaela Ionescu

A1 Journal Article in IEEE ACCESS

Event-based fractional order control

Isabela Roxana BirsIoana NascuClara-Mihaela IonescuCristina Muresan

A1 Journal Article in JOURNAL OF ADVANCED RESEARCH

Event-based implementation of fractional order IMC controllers for simple FOPDT processes

Cristina I. MuresanIsabela Roxana BirsEva H. Dulf

A1 Journal Article in MATHEMATICS

Experimental validation of the KC autotuner on a highly nonlinear vertical take-off and landing (VTOL) process

Robain De KeyserIsabela Roxana BirsCristina I. Muresan

A2 Journal Article in INTERNATIONAL JOURNAL OF ELECTRICAL AND ELECTRONIC ENGINEERING AND TELECOMMUNICATIONS

Mathematical modelling with experimental validation of viscoelastic properties in non-Newtonian fluids

Clara-Mihaela IonescuIsabela Roxana BirsDana CopotC., I MuresanR. Caponetto

A1 Journal Article in PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Robust hemodynamic control under general anesthesia conditions

Dana CopotCristina MuresanIsabela Roxana BirsLevente Kovacs

2019

A survey of recent advances in fractional order control for time delay systems

Isabela Roxana BirsCristina MuresanIoana NascuClara-Mihaela Ionescu

A1 Journal Article in IEEE ACCESS

Alternative approximation method for time delays in an IMC scheme

Cristina I. MuresanIsabela Roxana BirsCosmin DarabOvidiu ProdanRobain De Keyser

An autotuning method for a fractional order PD controller for vibration suppression

Cristina I. MuresanRobain De KeyserIsabela Roxana BirsSilviu FoleaOvidiu Prodan

An interdisciplinary, low-cost methodological framework for analysing dynamical material properties for control-related applications

Isabela Roxana BirsMihaela GhitaMaria GhitaDana CopotCristina I. MuresanClara-Mihaela Ionescu

Approximation methods for FO-IMC controllers for time delay systems

Cristina I. MuresanIsabela Roxana BirsOvidiu ProdanIoana NascuRobain De Keyser

Design and practical implementation of a fractional order proportional integral controller (FOPI) for a poorly damped fractional order process with time delay

Isabela Roxana BirsCristina MuresanDana CopotIoan NascuClara-Mihaela Ionescu

Electrical circuits to mimic respiratory diseases : an interdisciplinary bachelor project

Maria GhitaJasper JuchemMihaela GhitaIsabela Roxana BirsRicardo Alfredo Cajo DiazDana CopotClara-Mihaela Ionescu

Experiment design and estimation methodology of varying properties for non-Newtonian fluids

Isabela Roxana BirsDana CopotClaudio PilatoMihaela GhitaRiccardo CaponettoCristina I. MuresanClara-Mihaela Ionescu

Fractional-order modeling of impedance measurements in a blood-resembling experimental setup

Isabela Roxana BirsDana CopotMihaela GhitaCristina MuresanClara-Mihaela Ionescu

Identification for control of suspended objects in non-Newtonian fluids

Isabela Roxana BirsCristina MuresanDana CopotIoana NascuClara-Mihaela Ionescu

A1 Journal Article in FRACTIONAL CALCULUS AND APPLIED ANALYSIS

Robust fractional order PI control for cardiac output stabilisation

Isabela Roxana BirsDana CopotCristina I MuresanRobain De KeyserClara-Mihaela Ionescu

Tuning of fractional order proportional integral/proportional derivative controllers based on existence conditions

Cristina I. MuresanIsabela Roxana BirsClara-Mihaela IonescuRobain De Keyser

A1 Journal Article in PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART I-JOURNAL OF SYSTEMS AND CONTROL ENGINEERING

2018

A novel fractional-order model and controller for vibration suppression in flexible smart beam

Cristina I. MuresanSilviu FoleaIsabela Roxana BirsClara-Mihaela Ionescu

A1 Journal Article in NONLINEAR DYNAMICS

Analytical modeling and preliminary fractional order velocity control of a small scale submersible

Isabela Roxana BirsCristina MuresanOvidiu ProdanSilviu FoleaClara-Mihaela Ionescu

Benchmark challenge : a robust fractional order control autotuner for the refrigeration systems based on vapor compression

Cristina I. MuresanRobain De KeyserIsabela Roxana BirsDana CopotClara-Mihaela Ionescu

Experimental results of fractional order PI controller designed for second order plus dead time (SOPDT) processes

Isabela Roxana BirsCristina I. MuresanIoana NascuSilviu FoleaClara-Mihaela Ionescu

Experimental validation of a novel auto-tuning method for a fractional order PI controller on an UR10 robot

Cristina I. MuresanCosmin CopotIsabela Roxana BirsRobain De KeyserSteve VanlanduitClara-Mihaela Ionescu

A2 Journal Article in ALGORITHMS

Fractional order based velocity control system for a nanorobot in non-Newtonian fluids

C.I. MuresanIsabela Roxana BirsS. FoleaClara-Mihaela Ionescu

A1 Journal Article in BULLETIN OF THE POLISH ACADEMY OF SCIENCES-TECHNICAL SCIENCES

Fractional order modeling and control of a carrier prototype for targeted drug delivery

Isabela Roxana BirsCristina MuresanSilviu FoleaOvidiu ProdanClara-Mihaela Ionescu

Structural vibration attenuation using a fractional order PD controller designed for a fractional order process

Isabela Roxana BirsCristina I. MuresanOvidiu ProdanSilviu C. FoleaClara-Mihaela Ionescu

2017

Discrete-time implementation and experimental validation of a fractional order PD controller for vibration suppression in airplane wings

Silviu FoleaRobain De KeyserIsabela Roxana BirsCristina I. MuresanClara-Mihaela Ionescu

A1 Journal Article in ACTA POLYTECHNICA HUNGARICA

Fractional order modeling and control of a smart beam

Cristina I. MuresanSilviu FoleaIsabela Roxana BirsClara-Mihaela Ionescu

2016

Comparative analysis and experimental results of advanced control strategies for vibration suppression in aircraft wings

Isabela Roxana BirsSilviu FoleaDana CopotOvidiu ProdanCristina-I. Muresan