Research Explorer

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Researcher

Isabel Van Audenhove

Awards & Distinctions

13 Results

2022

Nuclear fascin regulates cancer cell survival

Campbell D LawsonSamantha PeelAsier JayoAdam CorriganPreeti IyerMabel Baxter DalrympleRichard J MarshSusan CoxIsabel Van AudenhoveJan Gettemans et al.

A1 Journal Article in ELIFE

2017

EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research

Jan Van DeunPieter MestdaghPatrizia AgostinisÖzden AkaySushma AnandJasper AnckaertZoraida Andreu MartinezTine BaetensEls BegheinLaurence Bertier et al.

A1 Journal Article in NATURE METHODS

Inhibitory cortactin nanobodies delineate the role of NTA- and SH3-domain-specific functions during invadopodium formation and cancer cell invasion

Laurence BertierCiska BoucherieOlivier ZwaenepoelBerlinda VanlooMarleen Van TroysIsabel Van AudenhoveJan Gettemans

A1 Journal Article in FASEB JOURNAL

VCA nanobodies target N-WASp to reduce invadopodium formation and functioning

Tim HebbrechtIsabel Van AudenhoveOlivier ZwaenepoelAdriaan VerhelleJan Gettemans

A1 Journal Article in PLOS ONE

2016

A new survivin tracer tracks, delocalizes and captures endogenous survivin at different subcellular locations and in distinct organelles

Els BegheinIsabel Van AudenhoveOlivier ZwaenepoelAdriaan VerhelleAriane De GanckJan Gettemans

A1 Journal Article in SCIENTIFIC REPORTS

Fascin rigidity and L-plastin flexibility cooperate in cancer cell invadopodia and filopodia

Isabel Van AudenhoveMajken DenertCiska BoucherieLeen PietersMaria CornelissenJan Gettemans

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Nanobodies as versatile tools to understand, diagnose, visualize and treat cancer

Isabel Van AudenhoveJan Gettemans

A1 Journal Article in EBIOMEDICINE

Nanobody-based high resolution mapping of actin regulators in cancer and immune cell invadosomes

Isabel Van AudenhoveJan Gettemans

Use of nanobodies to localize endogenous cytoskeletal proteins and to determine their contribution to cancer cell invasion by using an ECM degradation assay

Isabel Van AudenhoveJan Gettemans

Bookchapter in Cytoskeleton : methods and protocols

2015

Fascin actin bundling controls podosome turnover and disassembly while cortactin is involved in podosome assembly by its SH3 domain in THP-1 macrophages and dendritic cells

Isabel Van AudenhoveNincy DebeufCiska BoucherieJan Gettemans

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

2014

Combination of interleukin-12 gene therapy, metronomic cyclophosphamide and DNA cancer vaccination directs all arms of the immune system towards tumor eradication

Sofie DeniesLaetitia CiccheleroIsabel Van AudenhoveNiek Sanders

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization

Isabel Van AudenhoveCiska BoucherieLeen PietersOlivier ZwaenepoelBerlinda VanlooEvelien MartensCharlotte VerbruggeGholamreza Hassanzadeh-GhassabehJoël VandekerckhoveMaria Cornelissen et al.

A1 Journal Article in FASEB JOURNAL

2013

Mapping cytoskeletal protein function in cells by means of nanobodies

Isabel Van AudenhoveKatrien Van ImpeDavid Ruano-GallegoSarah De ClercqKevin De MuynckBerlinda VanlooHanne VerstraeteLuis Á FernándezJan Gettemans

A1 Journal Article in CYTOSKELETON