Research Explorer

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Researcher

Irma Lemmens

Awards & Distinctions

41 Results

2022

An unexpected encounter : respiratory syncytial virus nonstructural protein 1 interacts with mediator subunit MED25

Tessa Van RoyenKoen SedeynGeorgios MoschonasWendy ToussaintM VuylstekeDelphi Van HaverFrancis ImpensSven EyckermanIrma LemmensJan Tavernier et al.

A1 Journal Article in JOURNAL OF VIROLOGY

2021

Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function

Karen RosierMolly T. McDevittJoél SmetBrendan J. FloydMaxime VerschooreMaria J. MarcaidaCraig A. BingmanIrma LemmensMatteo Dal PeraroJan Tavernier et al.

A1 Journal Article in ISCIENCE

2020

A reference map of the human binary protein interactome

Katja LuckDae-Kyum KimLuke LambourneKerstin SpirohnBridget E. BeggWenting BianRuth BrignallTiziana CafarelliFrancisco J. Campos-LaborieBenoit Charloteaux et al.

A1 Journal Article in NATURE

2019

Discovering cellular protein-protein interactions : technological strategies and opportunities

Kevin TitecaIrma LemmensJan TavernierSven Eyckerman

A1 Journal Article in MASS SPECTROMETRY REVIEWS

2018

KISS : a mammalian two-hybrid method for in situ analysis of protein-protein interactions

Delphine MasschaeleSarah GerloIrma LemmensSam LievensJan Tavernier

Bookchapter in Two-hybrid systems : methods and protocols

2017

MAPPI-DAT : data management and analysis for protein-protein interaction data from the high-throughput MAPPIT cell microarray platform

Surya GuptaVeronic De PuysseleyrJosé Van Der HeydenDavy MaddeleinIrma LemmensSam LievensSven DegroeveJan TavernierLennart Martens

A1 Journal Article in BIOINFORMATICS

2016

A combined binary interaction and phenotypic map of C. elegans cell polarity proteins

Thijs KoormanDiana KlompstraMonique van der VoetIrma LemmensJoão J RamalhoSusan NieuwenhuizeSander van den HeuvelJan TavernierJeremy NanceMike Boxem

A1 Journal Article in NATURE CELL BIOLOGY

An omics strategy to unravel the role of the β2-adrenergic receptor in inflammation

Sarah GerloGuy LaureysKrzysztof KolmusSven EyckermanKris GevaertIrma LemmensJan Tavernier

Proteome-scale binary interactomics in human cells

Sam LievensJosé Van Der HeydenDelphine MasschaeleLeentje De CeuninckIoanna PettaSurya GuptaVeronic De PuysseleyrVirginie VauthierIrma LemmensDries De Clercq et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

2015

Ryanodine receptors are targeted by anti-apoptotic Bcl-X-L involving its BH4 domain and Lys87 from its BH3 domain

Tim VervlietIrma LemmensElien VandermarliereElke DecrockHristina IvanovaGiovanni MonacoVincenzo SorrentinoNael Nadif KasriLudwig MissiaenLennart Martens et al.

A1 Journal Article in SCIENTIFIC REPORTS

Spatiotemporal 16p11.2 protein network implicates cortical late mid-fetal brain development and KCTD13-Cul3-RhoA pathway in psychiatric diseases

Guan Ning LinRoser CorominasIrma LemmensXinping YangJan TavernierDavid E HillMarc VidalJonathan SebatLilia M Iakoucheva

A1 Journal Article in NEURON

2014

A proteome-scale map of the human interactome network

Thomas RollandMurat TaşanBenoit CharloteauxSamuel J PevznerQuan ZhongNidhi SahniSong YiIrma LemmensCelia FontanilloRoberto Mosca et al.

A1 Journal Article in CELL

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

Yao-Cheng LinMorgane BooneLeander MeurisIrma LemmensNadine Van RoyArne SoeteJoke ReumersMatthieu MoisseStéphane PlaisanceRadoje Drmanac et al.

A1 Journal Article in NATURE COMMUNICATIONS

Kinase Substrate Sensor (KISS), a mammalian in situ protein interaction sensor

Sam LievensSarah GerloIrma LemmensDries De ClercqMartijn RisseeuwNele VanderroostAnne-Sophie De SmetElien RuyssinckEric ChevetSerge Van Calenbergh et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser CorominasXinping YangGuan Ning LinShuli KangYun ShenLila GhamsariMartin BrolyMaria RodriguezStanley TamShelly A Trigg et al.

A1 Journal Article in NATURE COMMUNICATIONS

2013

MAPPIT and Co: the importance of system artifacts

Jan TavernierLeentje De CeuninckSarah GerloIrma LemmensSam LievensJosé Van Der HeydenJoris Wauman

2012

Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses

Nicolas SimonisJean-François RualIrma LemmensMathieu BoxusTomoko Hirozane-KishikawaJean-Stéphane GatotAmélie DricotTong HaoDidier VertommenSébastien Legros et al.

A1 Journal Article in RETROVIROLOGY

Random mutagenesis MAPPIT analysis identifies binding sites for Vif and Gag in both cytidine deaminase domains of Apobec3G

Isabel UyttendaeleDelphine LavensDominiek CatteeuwIrma LemmensCelia BovijnJan TavernierFrank Peelman

A1 Journal Article in PLoS ONE

2011

MAPPIT: a protein interaction toolbox built on insights in cytokine receptor signaling

Sam LievensFrank PeelmanKarolien De BosscherIrma LemmensJan Tavernier

A1 Journal Article in CYTOKINE & GROWTH FACTOR REVIEWS

2010

Large-scale protein interactome mapping: strategies and opportunities

Sam LievensSven EyckermanIrma LemmensJan Tavernier

A1 Journal Article in EXPERT REVIEW OF PROTEOMICS

Strategies towards high-quality binary protein interactome maps

Irma LemmensSam LievensJan Tavernier

A1 Journal Article in JOURNAL OF PROTEOMICS

2009

An empirical framework for binary interactome mapping

Kavitha VenkatesanJean-Francois RualAlexei VazquezUlrich StelzlIrma LemmensTomoko Hirozane-KishikawaTong HaoMartina ZenknerXiaofeng XinKwang-Il Goh et al.

A1 Journal Article in NATURE METHODS

An experimentally derived confidence score for binary protein-protein interactions

Pascal BraunMurat TasanMatija DrezeMiriam Barrios-RodilesIrma LemmensHaiyuan YuJulie M. SahalieRyan R. MurrayLuba RoncariAnne-Sophie De Smet et al.

A1 Journal Article in NATURE METHODS

Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network

Nicolas SimonisJean-Francois RualAnne-Ruxandra CarvunisMurat TasanIrma LemmensTomoko Hirozane-KishikawaTong HaoJulie M. SahalieKavitha VenkatesanFana Gebreab et al.

A1 Journal Article in NATURE METHODS

MAPPIT (Mammalian Protein-Protein Interaction Trap) analysis of early steps in Toll-like receptor signalling

Peter UlrichtsIrma LemmensDelphine LavensRudi BeyaertJan Tavernier

Bookchapter in Toll-like receptors : methods and protocols

Mammalian two-hybrids come of age

Sam LievensIrma LemmensJan Tavernier

A1 Journal Article in TRENDS IN BIOCHEMICAL SCIENCES

2008

A protein domain-based interactome network for C. elegans early embryogenesis

Mike BoxemZoltan MaligaNiels KlitgordNa LiIrma LemmensMiyeko ManaLorenzo de LichterveldeJoram D MulDiederik van de PeutMaxime Devos et al.

A1 Journal Article in CELL

High-quality binary protein interaction map of the yeast interactome network

HY YUP BRAUNMA YILDIRIMIrma LemmensK VENKATESANJ SAHALIET HIROZANE-KISHIKAWAF GEBREABN LIN SIMONIS et al.

A1 Journal Article in SCIENCE

MAPPIT (MAmmalian Protein-Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells

Els PattynDelphine LavensJosé Van Der HeydenAnnick VerheeSam LievensIrma LemmensS HALLENBERGERD JOCHMANSJan Tavernier

A1 Journal Article in JOURNAL OF VIROLOGICAL METHODS

MAPPIT: a versatile tool to study cytokine receptor signalling

Irma LemmensSam LievensJan Tavernier

A1 Journal Article in BIOCHEMICAL SOCIETY TRANSACTIONS

2007

Mammalian protein-protein interaction trap (MAPPIT) analysis of STAT5, CIS, and SOCS2 interactions with the growth hormone receptor

Isabel UyttendaeleIrma LemmensAnnick VerheeAnne-Sophie De SmetJoël VandekerckhoveDelphine LavensFrank PeelmanJan Tavernier

A1 Journal Article in MOLECULAR ENDOCRINOLOGY

The MAPPIT toolbox: novel strategies to analyze molecular interactions in intact cells

Jan TavernierIrma LemmensSam Lievens

2006

Analysis of leptin signalling in hematopoietic cells using an adapted MAPPIT strategy

Tony MontoyeJulie PiessevauxDelphine LavensJoris WaumanDominiek CatteeuwJoël VandekerckhoveIrma LemmensJan Tavernier

A1 Journal Article in FEBS LETTERS

Reverse MAPPIT detects disruptors of protein-protein interactions in human cells

Irma LemmensSam LievensSven EyckermanJan Tavernier

A1 Journal Article in NATURE PROTOCOLS

Two-hybrid and its recent adaptations

Sam LievensIrma LemmensTony MontoyeSven EyckermanJan Tavernier

A2 Journal Article in DRUG DISCOVERY TODAY. TECHNOLOGIES

2005

A systematic scan of interactions with tyrosine motifs in the erythropoietin receptor using a mammalian 2-hybrid approach

Tony MontoyeIrma LemmensDominiek CatteeuwSven EyckermanJan Tavernier

A1 Journal Article in BLOOD

Reverse MAPPIT: screening for protein-protein interaction modifiers in mammalian cells

Sven EyckermanIrma LemmensDominiek CatteeuwAnnick VerheeJoël VandekerckhoveSam LievensJan Tavernier

A1 Journal Article in NATURE METHODS

2003

Heteromeric MAPPIT: a novel strategy to study modification-dependent protein-protein interactions in mammalian cells

Irma LemmensSven EyckermanLennart ZabeauDominiek CatteeuwEls VertentenK VERSCHUEREND HUYLEBROECKJoël VandekerckhoveJan Tavernier

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2002

Design and use of a mammalian protein-protein interaction trap (MAPPIT)

Sven EyckermanIrma LemmensSam LievensJ VAN DER HEYDENA VERHEEJoël VandekerckhoveJan Tavernier

A2 Journal Article in Science's signal transduction knowledge environment

MAPPIT: a cytokine receptor-based two-hybrid method in mammalian cells.

Jan TavernierSven EyckermanIrma LemmensJ VAN DER HEYDENJoël VandekerckhoveXaveer Van Ostade

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

2001

Design and application of a cytokine-receptor-based interaction trap.

Sven EyckermanA VERHEEJ VAN DER HEYDENIrma LemmensXaveer Van OstadeJoël VandekerckhoveJan Tavernier

A1 Journal Article in NATURE CELL BIOLOGY