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Researcher

Iris Nelen

Profile

Projects

Publications & Research Data

Activities

Awards & Distinctions

Patents

2 Results

2026

Targeting replication stress in neuroblastoma by exploiting the synergistic potential of second generation RRM2 and CHK1 inhibitors

Iris NelenSoetkin LeysSarah-Lee BekaertFanny De VloedFien MartensEllen SandersAngeline Praveena Enton RajAnnika JeschkeShunya OhmuraThomas G P Grünewald et al.

A1 Journal Article in CELL DEATH & DISEASE

2026

2022

RRM2 enhances MYCN driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Lisa DepestelCarolina de Carvalho NunesLiselot MusIris NelenLouis DelhayeKaylee KellerVolodimir OlexioukFanny De VloedEllen SandersAline Eggermont et al.

C3 Conference

2022