Research Explorer

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Researcher

Igor Fijalkowski

Publications & Research Data

Awards & Distinctions

28 Results

2026

QKI dysregulation induces extensive splicing changes in T-cell acute lymphoblastic leukemia

Bruno PalhaisNitesh D. SharmaIgor FijalkowskiTim PietersDieter DeforceFilip Van NieuwerburghPieter MestdaghPanagiotis NtziachristosKsenia Matlawska-WasowskaPieter Van Vlierberghe

A1 Journal Article in HAEMATOLOGICA

2025

Combinatorial targeting of metabolic vulnerabilities in t-cell leukemia through NAMPT inhibition

Laura GuerreroKasper Thorhauge ChristensenIgor FijalkowskiCristina BorinTim PietersJonas De KeselManou WittouckJolien Van LaereFilip Van NieuwerburghNitesh Sharma et al.

HNRNPC and m6A RNA methylation control oncogenic transcription and metabolism in T-cell leukemia

Jonas De KeselIgor FijalkowskiTim PietersCristina BorinKasper Thorhauge ChristensenManou WittouckJolien Van LaereLaura GuerreroLindy ReunesMarino Caruso et al.

A1 Journal Article in BLOOD

SOX11 skews T-cell development and synergizes with LMO2 and MYCN to form T-cell acute lymphoblastic leukemia in mouse models

André Pedro Pinto De AlmeidaKasper Thorhauge ChristensenIgor FijalkowskiMarlies Vanden BemptJan CoolsTom TaghonPanagiotis NtziachristosPieter Van VlierbergheSteven GoossensTim Pieters

TET2 mutations drive cell-autonomous type I interferon production and selective advantage through TRIM4 silencing

Baosen JiaIgor FijalkowskiManon JaudMinh NguyenLewis TomalinEmmanuel OlivierChih-wei FanVrinda JethaliaNatthakan ThongonMax Dougherty et al.

Virotrap Reveals <i>Salmonella</i> SopB as A Ubiquitinated Cargo for Host ESCRT-0

Margaux De MeyerAnnick VerheeHanna GrzesikDelphine De SutterJon HuygheLouis DelhayeTessa Van de SteeneIgor FijalkowskiVeronique JonckheereLeander Meuris et al.

2024

A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia

Lisa DemoenFilip MatthijssensLindy ReunesBruno PalhaisBéatrice LintermansSara T'SasIgor FijalkowskiJoachim TaminauMuluembet Z. AkeleSiska Van Belle et al.

A1 Journal Article in SCIENCE ADVANCES

A positive feedback loop regulation between NOTCH1 and USP11 in T-cell leukemia

Igor FijalkowskiJin WangQi JinJolien Van LaereValentina SerafinJohn D. CrispinoPanagiotis Ntziachristos

A1 Journal Article in LEUKEMIA

Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T-cell lymphoblastic leukemia

André Pedro Pinto De AlmeidaSara T'SasLuca PagliaroIgor FijalkowskiWouter SleeckxHannah Van SteenbergeRaffaella ZamponiBéatrice LintermansWouter Van LoockeBruno Palhais et al.

A1 Journal Article in HEMASPHERE

Proteins à la carte : riboproteogenomic exploration of bacterial N-terminal proteoform expression

Igor FijalkowskiValdes SnauwaertPetra Van Damme

A1 Journal Article in MBIO

2023

Exposing the small protein load of bacterial life

Laure SimoensIgor FijalkowskiPetra Van Damme

A1 Journal Article in FEMS MICROBIOLOGY REVIEWS

2022

Hidden in plain sight : challenges in proteomics detection of small ORF-encoded polypeptides

Igor FijalkowskiPatrick WillemsVeronique JonckheereLaure SimoensPetra Van Damme

A2 Journal Article in MICROLIFE

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

Qi JinBlanca Gutierrez DiazTim PietersYalu ZhouSonali NarangIgor FijalkowskiCristina BorinJolien Van LaereMonique PaytonByoung-Kyu Cho et al.

A1 Journal Article in SCIENCE ADVANCES

Selective ribosome profiling reveals a role for SecB in the co-translational inner membrane protein biogenesis

Lena EismannIgor FijalkowskiCarla Verónica GalmozziJiří KoubekFrank TippmannPetra Van DammeGünter Kramer

A1 Journal Article in CELL REPORTS

Splicing dysregulation in human hematologic malignancies : beyond splicing mutations

Jonas De KeselIgor FijalkowskiJustin TaylorPanagiotis Ntziachristos

A1 Journal Article in TRENDS IN IMMUNOLOGY

2021

Capturing salmonella SspH2 host targets in virus-like particles

Margaux De MeyerIgor FijalkowskiVeronique JonckheereDelphine De SutterSven EyckermanPetra Van Damme

A1 Journal Article in FRONTIERS IN MEDICINE

Small protein enrichment improves proteomics detection of sORF encoded polypeptides

Igor FijalkowskiMarlies PeetersPetra Van Damme

A1 Journal Article in FRONTIERS IN GENETICS

2020

Bacterial riboproteogenomics : the era of N-terminal proteoform existence revealed

Daria FijalkowskaIgor FijalkowskiPatrick WillemsPetra Van Damme

A1 Journal Article in FEMS MICROBIOLOGY REVIEWS

Lost and found : re-searching and re-scoring proteomics data aids genome annotation and improves proteome coverage

Patrick WillemsIgor FijalkowskiPetra Van Damme

A1 Journal Article in MSYSTEMS

2017

The Lrp4R1170Q homozygous knock-in mouse recapitulates the bone phenotype of sclerosteosis in humans

E BoudinT YorganIgor FijalkowskiS SonntagE SteenackersG HendrickxS PeetersA De MaréB VervaetA Verhulst et al.

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

2016

A novel domain-specific mutation in a sclerosteosis patient suggests a role of LRP4 as an anchor for sclerostin in human bone

Igor FijalkowskiE GeetsE SteenackersV Van HoofFJ RamosG MortierAM FortunaW Van HulE Boudin

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

Eight mutations including 5 novel ones in the COL1A1 gene in Czech patients with osteogenesis imperfecta

L HruskovaIgor FijalkowskiW Van HulI MarikG MortierP MartasekI Mazura

A1 Journal Article in BIOMEDICAL PAPERS - OLOMOUC

Further delineation of facioaudiosymphalangism syndrome : description of a family with a novel NOG mutation and without hearing loss

A BayatIgor FijalkowskiT AndersenSA AbdulmunemJ van den EndeW Van Hul

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Genetic control of bone mass

E BoudinIgor FijalkowskiG HendrickxW Van Hul

A1 Journal Article in MOLECULAR AND CELLULAR ENDOCRINOLOGY

2014

Sclerosing bone dysplasias : leads toward novel osteoporosis treatments

Igor FijalkowskiE BoudinG MortierW Van Hul

A1 Journal Article in CURRENT OSTEOPOROSIS REPORTS

Variation in the Kozak sequence of WNT16 results in an increased translation and is associated with osteoporosis related parameters

G HendrickxE BoudinIgor FijalkowskiTL NielsenM AndersenK BrixenW Van Hul

A1 Journal Article in BONE

2013

Mutations in sFRP1 or sFRP4 are not a common cause of craniotubular hyperostosis

E BoudinE PitersIgor FijalkowskiG StevenheydensE SteenackersO KuisminJS MoilanenG MortierW Van Hul

A1 Journal Article in BONE

The role of extracellular modulators of canonical Wnt signaling in bone metabolism and diseases

E BoudinIgor FijalkowskiE PitersW Van Hul

A1 Journal Article in SEMINARS IN ARTHRITIS AND RHEUMATISM