Research Explorer

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Researcher

Hubert Thierens

Awards & Distinctions

332 Results

2022

Tumour characteristics of screen-detected and interval cancers in the Flemish Breast Cancer Screening Programme : a mammographic breast density study

Lore TimmermansIsabel De BrabanderNancy Van DammeLuc BleyenPatrick MartensKoen Van HerckHubert ThierensKlaus BacherHerman Depypere

A1 Journal Article in MATURITAS

2019

Flemish Breast Cancer Screening programme : is stratification of women according to breast density indicated?

Lore TimmermansKlaus BacherHubert ThierensKoen Van Herck

2018

A new approach for modeling patient overall radiosensitivity and predicting multiple toxicity endpoints for breast cancer patients

Chamberlain MbahKim De RuyckSilke De SchrijverCharlotte De SutterKimberly SchiettecatteChristel MontenLeen PaelinckWilfried De NeveHubert ThierensCatharine West et al.

A1 Journal Article in ACTA ONCOLOGICA

Challenges in predicting normal tissue toxicity in radiotherapy

Chamberlain MbahLiv VeldemanOlivier ThasHubert Thierens

DNA double strand breaks induced by low dose mammography X-rays in breast tissue: A pilot study

Julie DepuydtTanguy ViaenePhillip BlondeelNathalie RocheRudy Van den BroeckeHubert ThierensAnne Vral

A1 Journal Article in ONCOLOGY LETTERS

2017

Investigation of the influence of calibration practices on cytogenetic laboratory performance for dose estimation

François TrompierMarion BaumannLleonard BarriosEric GregoireMichael AbendElizabeth AinsburyStephen BarnardJoan Francesc BarquineroJuan Antonio BautistaBeata Brzozowska et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

RENEB : running the European network of biological dosimetry and physical retrospective dosimetry

Ulrike KulkaMichael AbendElizabeth AinsburyChristophe BadieJoan Francesc BarquineroLleonard BarriosChristina BeinkeEmanuela BortolinAlexandra CucuAndrea De Amicis et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

RENEB intercomparison exercises analyzing micronuclei (Cytokinesis-block Micronucleus Assay)

Julie DepuydtAns BaeyensStephen BarnardChristina BeinkeAnett BenedekPhilip BeukesIwona BuraczewskaFirouz DarroudiStefania De SanctisInmaculada Dominguez et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Screen-detected versus interval cancers : effect of imaging modality and breast density in the Flemish Breast Cancer Screening Programme

Lore TimmermansLuc BleyenKlaus BacherKoen Van HerckKim LemmensChantal Van OngevalAndre Van SteenPatrick MartensIsabel De BrabanderMathieu Goossens et al.

A1 Journal Article in EUROPEAN RADIOLOGY

Uncertainty of fast biological radiation dose assessment for emergency response scenarios

Elizabeth A AinsburyManuel HiguerasPedro PuigJochen EinbeckDaniel SamagaJoan Francesc BarquineroLleonard BarriosBeata BrzozowskaPaola FattibeneEric Gregoire et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

2016

A semi-automated FISH-based micronucleus-centromere assay for biomonitoring of hospital workers exposed to low doses of ionizing radiation

Anne VralVeerle DecorteJulie DepuydtAndré WambersieHubert Thierens

A1 Journal Article in MOLECULAR MEDICINE REPORTS

In vitro cellular radiosensitivity in relationship to late normal tissue reactions in breast cancer patients : a multi-endpoint case-control study

Charlot VandevoordeJulie DepuydtLiv VeldemanWilfried De NeveNatividad SebastiaGreet WiemeAnnelot BaertSofie De LangheJan PhilippéHubert Thierens et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients

Christian Nicolaj AndreassenBarry S RosensteinSarah L KernsHarry OstrerDirk De RuysscherJamie A CesarettiGillian C BarnettAlison M DunningLeila DorlingCatharine ML West et al.

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Pitfalls in prediction modeling for normal tissue toxicity in radiation therapy: an illustration with the individual radiation sensitivity and mammary carcinoma risk factor investigation cohorts

Chamberlain MbahHubert ThierensOlivier ThasJan De NeveJenny Chan-ClaudePetra SeibodAkke BotmaCatherine WestKim De Ruyck

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Radiation sensitivity of human CD34+ cells versus peripheral blood T lymphocytes of newborns and adults: DNA repair and mutagenic effects

Charlot VandevoordeAnne VralBart VandekerckhoveJan PhilippéHubert Thierens

A1 Journal Article in RADIATION RESEARCH

The cellular response to different radiation qualities in relation to breast cancer screening and treatment

Julie DepuydtAnne VralHubert Thierens

The role of Size-Specific Dose Estimate (SSDE) in patient-specific organ dose and cancer risk estimation in paediatric chest and abdominopelvic CT examinations

Caro FranckCharlot VandevoordeIngeborg GoethalsPeter SmeetsEric AchtenKoenraad VerstraeteHubert ThierensKlaus Bacher

A1 Journal Article in EUROPEAN RADIOLOGY

2015

Analysis of metal artifact reduction tools for dental hardware in CT scans of the oral cavity: kVp, iterative reconstruction, dual-energy CT, metal artifact reduction software: does it make a difference?

An De CropJan CasselmanTom Van HoofMelissa DierensElke VereeckeNicolas BossuJaime PamplonaKatharina D'HerdeHubert ThierensKlaus Bacher

A1 Journal Article in NEURORADIOLOGY

Biomarker investigation of the health effects of CT X-ray exposure in children : a plea to 'image gently'

Charlot VandevoordeHubert ThierensKlaus Bacher

Correlation of clinical and physical-technical image quality in chest CT : a human cadaver study applied on iterative reconstruction

An De CropPeter SmeetsTom Van HoofMEREL VERGAUWENTom DewaeleMATHIAS VAN BORSELEric AchtenKoenraad VerstraeteKatharina D'HerdeHubert Thierens et al.

A1 Journal Article in BMC MEDICAL IMAGING

Dose-reducing technology in diagnostic cardiac X-ray imaging

Liesbeth ElootHubert ThierensKlaus Bacher

EPI-CT: in vitro assessment of the applicability of the γ-H2AX-foci assay as cellular biomarker for exposure in a multicentre study of children in diagnostic radiology

Charlot VandevoordeMaria GomolkaUte RoesslerDaniel SamagaCarita LindholmMaria FernetJanet HallEileen PernotHoussein El SaghireSarah Baatout et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Image quality evaluation in X-ray medical imaging based on Thiel embalmed human cadavers

An De CropHubert ThierensKatharina D'Herde

Novel X-ray imaging technology enables significant patient dose reduction in interventional cardiology while maintaining diagnostic image quality

Liesbeth ElootHubert ThierensYvo TaeymansBENNY DRIEGHEJan De PooterSYLVIE VAN PETEGHEMDimitri BuytaertThomas GijsRégine LapereKlaus Bacher

A1 Journal Article in CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

Operational guidance for radiation emergency response organisations in Europe for using biodosimetric tools developed in EU MULTIBIODOSE project

Alicja JaworskaElizabeth A AinsburyPaola FattibeneCarita LindholmUrsula OestreicherKai RothkammHorst RommHubert ThierensFrancois TrompierPhilippe Voisin et al.

A1 Journal Article in RADIATION PROTECTION DOSIMETRY

Organ doses and radiation risk of computed tomographic coronary angiography in a clinical patient population: how do low-dose acquisition modes compare?

Liesbeth ElootDaniel DevosSTEPHEN VAN MEERBEECKEric AchtenKoenraad VerstraeteHubert ThierensKlaus Bacher

A1 Journal Article in JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY

Realising the European network of biodosimetry: RENEB-status quo

U KulkaL AinsburyM AtkinsonS BarnardR SmithJF BarquineroL BarriosC BassinetC BeinkeA Cucu et al.

A1 Journal Article in RADIATION PROTECTION DOSIMETRY

The first gamma-H2AX biodosimetry intercomparison exercise of the developing European biodosimetry network RENEB

S BarnardEA AinsburyJ Al-hafidhV HadjidekovaR HristovaC LindholmO Monteiro GilJ MoquetM MorenoU Rössler et al.

A1 Journal Article in RADIATION PROTECTION DOSIMETRY

γ-H2AX foci as in vivo effect biomarker in children emphasize the importance to minimize x-ray doses in paediatric CT imaging

Charlot VandevoordeCaro FranckKlaus BacherLuc BreysemMaria Helena SmetAdelard De BackerKris Van De MoortelePeter SmeetsHubert Thierens

A1 Journal Article in EUROPEAN RADIOLOGY

2014

A let-7 microRNA polymorphism in the KRAS 3'-UTR is prognostic in oropharyngeal cancer

Kim De RuyckFréderic DuprezLiesbeth FerdinandeChamberlain MbahEmmanuel Rios-VelazquezFrank HoebersMarleen PraetPhilippe DeronKatrien BonteErnst-Jan Speel et al.

A1 Journal Article in CANCER EPIDEMIOLOGY

Biological responses after low doses X-ray exposure: gene expression and mechanistic studies

Houssein El SaghireHubert ThierensSarah Baatout

Factors modifying the risk for developing acute skin toxicity after whole-breast intensity modulated radiotherapy

Sofie De LangheTHOMAS MULLIEZLiv VeldemanVincent RemouchampsAnnick van GrevelingMonique GilsoulELINE DE SCHEPPERKim De RuyckWilfried De NeveHubert Thierens

A1 Journal Article in BMC CANCER

Impact of the digitalisation of mammography on performance parameters and breast dose in the Flemish Breast Cancer Screening Programme

Lore TimmermansAn De HauwereKlaus BacherHilde BosmansKim LemmensLuc BleyenErik Van LimbergenPatrick MartensAndre Van SteenMargarete Mortier et al.

A1 Journal Article in EUROPEAN RADIOLOGY

Integrated models for the prediction of late genitourinary complaints after high-dose intensity modulated radiotherapy for prostate cancer: making informed decisions

Sofie De LangheGert De MeerleerKim De RuyckPiet OstValérie FonteyneWilfried De NeveHubert Thierens

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Intensity modulated radiotherapy induces pro-inflammatory and pro-survival responses in prostate cancer patients

Houssein El SaghireCharlot VandevoordePiet OstPieter MonsieursArlette MichauxGert De MeerleerSarah BaatoutHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF ONCOLOGY

Inter- and intra-laboratory comparison of a multibiodosimetric approach to triage in a simulated, large scale radiation emergency

Elizabeth AinsburyJenna Al-HafidhAinars BajinskisStephen BarnardJoan Fracesc BarquineroChristina BeinkeVirginie de GelderEric GregoireAlicja JaworskaCarita Lindholm et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Is a semi-automated approach indicated in the application of the automated micronucleus assay for triage purposes?

Hubert ThierensAnne VralCharlot VandevoordeVeerle VandersickelVirginie de GelderH RommU OestreicherK RothkammS BarnardE Ainsbury et al.

A1 Journal Article in RADIATION PROTECTION DOSIMETRY

Multibiodose radiation emergency triage categorization software

Elizabeth A AinsburyStephen BarnardLleonard BarriosPaola FattibeneVirginie de GelderEric GregoireCarita LindholmDavid LloydInger NergaardKai Rothkamm et al.

A1 Journal Article in HEALTH PHYSICS

Predicting normal tissue toxicity in radiotherapy : can we improve clinical decision-making?

Sofie De LangheHubert ThierensWilfried De Neve

Radiogenomics: radiobiology enters the era of big data and team science

Barry S RosensteinCatherine M WestSøren M BentzenJan AlsnerChristian Nicolaj AndreassenDavid AzriaGillian C BarnettMichael BaumannNeil BurnetJenny Chang-Claude et al.

Editorial material

The REQUITE project: validating predictive models and biomarkers of radiotherapy toxicity to reduce side-effects and improve quality of life in cancer survivors

C WestD AzriaJ Chang-ClaudeS DavidsonP LambinB RosensteinD De RuysscherC TalbotHubert ThierensR Valdagni et al.

Editorial material

Validation of semi-automatic scoring of dicentric chromosomes after simulation of three different irradiation scenarios

H RommE AinsburyS BarnardL BarriosJF BarquineroC BeinkeM DeperasE GregoireA KoivistoinenC Lindholm et al.

A1 Journal Article in HEALTH PHYSICS

Web-based scoring of the dicentric assay, a collaborative biodosimetric scoring strategy for population triage in large scale radiation accidents

H RommE AinsburyA BajinskisS BarnardJF BarquineroL BarriosC BeinkeR Puig-CasanovasM Deperas-KaminskaE Gregoire et al.

A1 Journal Article in RADIATION AND ENVIRONMENTAL BIOPHYSICS

2013

A predictive model for dysphagia following IMRT for head and neck cancer: introduction of the EMLasso technique

Kim De RuyckFréderic DuprezJoke WerbrouckNick SabbeSofie De LangheTom BoterbergIndira MadaniOlivier ThasWilfried De NeveHubert Thierens

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Acute radiation-induced nocturia in prostate cancer patients is associated with pretreatment symptoms, radical prostatectomy, and genetic markers in the TGFβ1 gene

Sofie De LangheKim De RuyckPiet OstValérie FonteyneJoke WerbrouckGert De MeerleerWilfried De NeveHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Automatic scoring of dicentric chromosomes as a tool in large scale radiation accidents

H RommE AinsburyS BarnardL BarriosJF BarquineroC BeinkeM DeperasE GregoireA KoivistoinenC Lindholm et al.

A1 Journal Article in MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Comparison of established and emerging biodosimetry assays

K RothkammC BeinkeH RommC BadieY BalagurunathanS BarnardN BernardH Boulay-GreeneM BrenguesA De Amicis et al.

A1 Journal Article in RADIATION RESEARCH

Early biomarkers related to secondary primary cancer risk in radiotherapy treated prostate cancer patients: IMRT versus IMAT

Joke WerbrouckPiet OstValérie FonteyneGert De MeerleerWilfried De NeveEvelien BogaertLaurence BeelsKlaus BacherAnne VralHubert Thierens

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Gene set enrichment analysis highlights different gene expression profiles in whole blood samples X-irradiated with low and high doses

Houssein El SaghireHubert ThierensPieter MonsieursArlette MichauxCharlot VandevoordeSarah Baatout

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Laboratory intercomparison of the cytokinesis-block micronucleus assay

H RommS BarnardH Boulay-GreeneA De AmicisS De SanctisM FrancoF HerodinA JonesU KulkaF Lista et al.

A1 Journal Article in RADIATION RESEARCH

Low doses of ionizing radiation induce immune-stimulatory responses in isolated human primary monocytes

Houssein El SaghireArlette MichauxHubert ThierensSarah Baatout

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Manual versus automated γ-H2AX foci analysis across five European laboratories: can this assay be used for rapid biodosimetry in a large scale radiation accident?

Kai RothkammStephen BarnardElizabeth A AinsburyJenna Al-HafidhJoan-Francesc BarquineroCarita LindholmJayne MoquetMarjo PeräläSandrine Roch-LefèvreHarry Scherthan et al.

A1 Journal Article in MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Relative biological effectiveness of mammography X-rays at the level of DNA and chromosomes in lymphocytes

Julie DepuydtAnnelot BaertVeerle VandersickelHubert ThierensAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Technical and clinical breast cancer screening performance indicators for computed radiography versus direct digital radiography

Hilde BosmansAn De HauwereKim LemmensFederica ZancaHubert ThierensChantal Van OngevalKoen Van HerckAndre Van SteenPatrick MartensLuc Bleyen et al.

A1 Journal Article in EUROPEAN RADIOLOGY

Three-dimensional rotational X-ray acquisition technique is reducing patients' cancer risk in coronary angiography

Liesbeth ElootKlaus BacherFemke SteenbekeBENNY DRIEGHEPeter GheeraertYvo TaeymansHubert Thierens

A1 Journal Article in CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

2012

Adipose derived-stem cells as source of endothelial cells for cardiac tissue engineering

Pamela SomersFrancesca ColazzoIvan CarubelliA ChesterMaria CornelissenHubert ThierensGuido Van Nooten

An optimized growth factor cocktail for ovine mesenchymal stem cells

Pamela SomersMaria CornelissenHubert ThierensGuido Van Nooten

A1 Journal Article in GROWTH FACTORS

Bioactive porcine matrices in heart valve tissue engineering

Pamela SomersFilip De SomerMaria CornelissenHubert ThierensGuido Van Nooten

A1 Journal Article in JOURNAL OF HEART VALVE DISEASE

Combining radiotherapy and sorafinib for treatment of hepatocellular carcinoma: an in vitro study of multicellular tumour sheroids

Koen MertensBieke LambertMaria CornelissenFilip De VosIngeborg GoethalsHans Van VlierbergheHubert Thierens

Correlation of contrast-detail analysis and clinical image quality assessment in chest radiography with a human cadaver study

An De CropKlaus BacherTom Van HoofPeter SmeetsBARBARA SMETMEREL VERGAUWENURSZULA KIENDYSPhilippe DuyckKoenraad VerstraeteKatharina D'Herde et al.

A1 Journal Article in RADIOLOGY

Decellularization of heart valve matrices : search for the ideal balance

Pamela SomersFilip De SomerMaria CornelissenHubert ThierensGuido Van Nooten

A1 Journal Article in ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY

Dose-length product of scanners correlates with DNA damage in patients undergoing contrast CT

Laurence BeelsKlaus BacherPeter SmeetsKoenraad VerstraeteAnne VralHubert Thierens

A1 Journal Article in EUROPEAN JOURNAL OF RADIOLOGY

Epigenetic changes in lymphocytes of solvent-exposed individuals

Lode GodderisKarel De RaedtAli M TabishKatrien PoelsNathalie MaertensKim De RuyckSimon BulterysHubert ThierensMaria K Viaene

A1 Journal Article in EPIGENOMICS

Impact of digitalization of mammographic units on average glandular doses in the Flemish Breast Cancer Screening Program

An De HauwereHubert Thierens

No association between TGF-β1 polymorphisms and radiation-induced lung toxicity in a European cohort of lung cancer patients

An M VoetsCary OberijeRobin B StruijkBart ReymenKim De RuyckHubert ThierensKatrien VandecasteeleWilfried De NeveRuud HoubenDirk De Ruysscher et al.

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Non-cytotoxic cross-linking of bioactive porcine matrices

Pamela SomersFilip De SomerMaria CornelissenHubert ThierensGuido Van Nooten

Platelet gel supernatant as a potential tool to repopulate acellular heart valves

Pamela SomersLieselot RobynsEvelien NolletFilip De SomerMaria CornelissenHubert ThierensGuido Van Nooten

A1 Journal Article in CELL PROLIFERATION

Realising the European Network of Biodosimetry (RENEB)

U KulkaL AinsburyM AtkinsonJF BarquineroL BarriosC BeinkeG BognarA CucuF DarroudiP Fattibene et al.

A1 Journal Article in RADIATION PROTECTION DOSIMETRY

2011

A semi-automated micronucleus-centromere assay to assess low-dose radiation exposure in human lymphocytes

Ans BaeyensRosemary SwansonOlivia HerdElizabeth AinsburyThulani MabhenguPascale WillemHubert ThierensJacobus P SlabbertAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Combined effect of polymorphisms in Rad51 and XRCC3 on breast cancer risk and chromosomal radiosensitivity

Anne VralPetra WillemsKathleen ClaesBruce PoppeAns BaeyensGianpaolo PerlettiHubert Thierens

A1 Journal Article in MOLECULAR MEDICINE REPORTS

Comparison of the colony formation and crystal violet cell proliferation assays to determine cellular radiosensitivity in a repair-deficient MCF10A cell line

Veerle VandersickelJacobus SlabbertHubert ThierensAnne Vral

A1 Journal Article in RADIATION MEASUREMENTS

DNA double-strand breaks induced by low-dose exposure to x-rays used in medical diagnostics

Laurence BeelsHubert ThierensAnne Vral

Development of a multicomponent prediction model for acute esophagitis in lung cancer patients receiving chemoradiotherapy

Kim De RuyckNick SabbeCary OberijeKatrien VandecasteeleOlivier ThasDirk De RuysscherPhillipe LambinJan Van MeerbeeckWilfried De NeveHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Lack of a correlation between γH2AX foci kinetics in lymphocytes and the severity of acute normal tissue reactions during IMRT treatment for head and neck cancer

Joke WerbrouckFréderic DuprezWilfried De NeveHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

The 4th International comparison on EPR dosimetry with tooth enamel, part 1: report on the results

P FattibeneA WieserE AdolfssonLA BenevidesM BraiFreddy CallensV ChumakV CiesielskiS Della MonacaK Emerich et al.

A1 Journal Article in RADIATION MEASUREMENTS

The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure

Anne VralMichel FenechHubert Thierens

A1 Journal Article in MUTAGENESIS

Virtual electron microscopy in cell biology

Sylvia MioneKlaus BacherHubert ThierensMaria Cornelissen

A1 Journal Article in MICROSCOPY RESEARCH AND TECHNIQUE

2010

Association of TGFβ1 polymorphisms involved in radiation toxicity with TGFβ1 secretion in vitro

Kim De RuyckLaurence BeelsJan Van MeerbeeckWilfried De NeveHubert Thierens

A1 Journal Article in CYTOKINE

Automated micronucleus (MN) scoring for population triage in case of large scale radiation events

Petra WillemsLiezel AugustJacobus SlabbertHorst RommUrsula OestreicherHubert ThierensAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

DNA double-strand break repair: association with cancer susceptibility and clinical radiosensitivity

Joke WerbrouckHubert ThierensWilfried De Neve

Dose response and repair kinetics of γ-H2AX foci induced by in vitro irradiation of whole blood and T-lymphocytes with X- and γ-radiation

Laurence BeelsJoke WerbrouckHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Early increase of radiation-induced gamma H2AX foci in a human Ku70/80 knockdown cell line characterized by an enhanced radiosensitivity

Veerle VandersickelJulie DepuydtBram Van BockstaeleGianpaolo PerlettiJan PhilippéHubert ThierensAnne Vral

A1 Journal Article in JOURNAL OF RADIATION RESEARCH

Early increase of radiation-induced γH2AX foci in a human Ku70/80 knockdown cell line characterized by an enhanced radiosensitivity

Veerle VandersickelJulie DepuydtBram Van BockstaeleGianpaolo PerlettiJan PhilippéHubert ThierensAnne Vral

A1 Journal Article in JOURNAL OF RADIATION RESEARCH

Establishment of a radiogenomics consortium

Catharine WestBarry S. RosensteinJan AlsnerDavid AzriaGillian BarnettAdrian BeggSoren BentzenNeil BurnetJenny Chang-ClaudeEric Chuang et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Genetic susceptibility in solvent induced neurobehavioral effects

Lode GodderisN MaertensVirginie de GelderA De LamperKim De RuyckM VernimmenS BulterysG MoensHubert ThierensMK Viaene

A1 Journal Article in NEUROTOXICITY RESEARCH

Genetic variation in three candidate genes and nicotine dependence, withdrawal and smoking cessation in hospitalized patients

Kim De RuyckKristiaan NackaertsLaurence BeelsJoke WerbrouckAnnick De VolderMarc MeysmanBihiyga SalhiJan Van MeerbeeckHubert Thierens

A1 Journal Article in PHARMACOGENOMICS

Lentivirus-mediated RNA interference of Ku70 to enhance radiosensitivity of human mammary epithelial cells

Veerle VandersickelM ManciniE MarrasP WillemsJ SlabbertJan PhilippéEllen DeschepperHubert ThierensG PerlettiAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Prediction of late normal tissue complications in RT treated gynaecological cancer patients: potential of the γ-H2AX foci assay and association with chromosomal radiosensitivity

Joke WerbrouckKim De RuyckLaurence BeelsAnne VralMarc Van EijkerenWilfried De NeveHubert Thierens

A1 Journal Article in ONCOLOGY REPORTS

Semi-automated micronucleus-centromere scoring in assessing cellular damage in patients exposed to low doses of ionizing radiation

Ans BaeyensJakobus P SlabbertRose SwansonHubert ThierensPetra WillemsAnne Vral

The radiosensitizing effect of Ku70/80 knockdown in MCF10A cells irradiated with X-rays and p(66)+Be(40) neutrons

Veerle VandersickelMonica ManciniJacobus SlabbertEmanuela MarrasHubert ThierensGianpaolo PerlettiAnne Vral

A1 Journal Article in RADIATION ONCOLOGY

The role of the Ku heterodimer in the response of human MCF10A cells to low-and high-LET radiation qualities

Veerle VandersickelAnne VralHubert Thierens

2009

A large-scale multicentre study of patient skin doses in interventional cardiology: dose–area product action levels and dose reference levels

Evelien BogaertKlaus BacherKim LemmensMarc CarlierWalter DesmetXavier De WagterDominique DjianClaude HanetGuy HeyndrickxVictor Legrand et al.

A1 Journal Article in BRITISH JOURNAL OF RADIOLOGY

A polymorphism in the promoter region of Ku70/XRCC6, associated with breast cancer risk and oestrogen exposure

Petra WillemsKim De RuyckRudy Van den BroeckeAmin MakarGianpaolo PerlettiHubert ThierensAnne Vral

A1 Journal Article in JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose and association with genetic polymorphisms in DNA DSB repair genes

Joke WerbrouckKim De RuyckFréderic DuprezLiv VeldemanKathleen ClaesMarc Van EijkerenTom BoterbergPetra WillemsAnne VralWilfried De Neve et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Association of TGFβ1 polymorphisms involved in radiation toxicity with TGFβ1 secretion in vitro

Kim De RuyckLaurence BeelsJan Van MeerbeeckWilfried De NeveHubert Thierens

Characterization of the c.190T > C missense mutation in BRCA1 codon 64 (Cys64Arg)

Petra WillemsV. MagriM. CretnikM. FasanoA. JakubowskaS. LevanatJ. LubinskiE. MarasV. MusaniHubert Thierens et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF ONCOLOGY

Does digital flat detector technology tip the scale towards better image quality or reduced patient dose in interventional cardiology?

Evelien BogaertKlaus BacherRégine LapereHubert Thierens

A1 Journal Article in EUROPEAN JOURNAL OF RADIOLOGY

Dose response relationships for chromosome aberrations induced by low doses of alpha-particle radiation

EJ TawnHubert Thierens

A1 Journal Article in RADIATION PROTECTION DOSIMETRY

Polymorphisms in DNA double-strand break repair genes: link with breast cancer susceptibility and in vitro chromosomal radiosensitivity.

Petra WillemsAnne VralHubert Thierens

The influence of small field sizes, penumbra, spot size and measurement depth on perturbation factors for microionization chambers

Frederik CropN ReynaertGEERT PITTOMVILSLeen PaelinckCarlos De WagterLuc VakaetHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

The micronucleus assay in radiation accidents

Hubert ThierensAnne Vral

A1 Journal Article in ANNALI DELL ISTITUTO SUPERIORE DI SANITA

The radiosensitizing effect of Ku70-80 knockdown by RNA interference in the MCF10A breast epithelial cell line irradiated with low LET X-rays and high LET radiotherapy neutrons

Veerle VandersickelM ManciniJP SlabbertE MarrasHubert ThierensG PerlettiAnne Vral

Typetesting of physical characteristics of digital mammography systems for screening within the Flemish breast cancer screening programme

Hubert ThierensHilde BosmansNico BulsAn De HauwereKlaus BacherJ JacobsP Clerinx

A1 Journal Article in EUROPEAN JOURNAL OF RADIOLOGY

γ-H2AX foci as biomarker for patient X-ray exposure in pediatric cardiac catheterization: are we underestimating radiation risks?

Laurence BeelsKlaus BacherDaniël De WolfJoke WerbrouckHubert Thierens

A1 Journal Article in Circulation

2008

A large-scale multicentre study in Belgium of dose area product values and effective doses in interventional cardiology using contemporary X-ray equipment

Evelien BogaertKlaus BacherHubert Thierens

A1 Journal Article in RADIATION PROTECTION DOSIMETRY

Chromosomal radiosensitivity in head and neck cancer patients: evidence for genetic predisposition?

Kim De RuyckVirginie de GelderMarc Van EijkerenTom BoterbergWilfried De NeveAnne VralHubert Thierens

A1 Journal Article in BRITISH JOURNAL OF CANCER

Discrepancies between in silico and in vitro data in the functional analysis of a breast cancer-associated polymorphism in the XRCC6/Ku70 gene

E MARRASPetra WillemsVeerle VandersickelI CERIANIHubert ThierensAnne VralG PERLETTI

A1 Journal Article in MOLECULAR MEDICINE REPORTS

Evaluation of Patient Dose and Image Receptor Performance in Interventional Cardiology

Evelien BogaertHubert Thierens

In vitro and in vivo evaluation of direct rhenium-188-labeled anti-CD52 monoclonal antibody alemtuzumab for radioimmunotherapy of B-cell chronic lymphocytic leukemia

Mario De DeckerKlaus BacherHubert ThierensGuido SlegersRudi DierckxFilip De Vos

A1 Journal Article in NUCLEAR MEDICINE AND BIOLOGY

Interventional cardiovascular procedures in Belgium: Effective dose and conversion factors

Evelien BogaertKlaus BacherHubert Thierens

On the calibration process of film dosimetry: OLS inverse regression versus WLS inverse prediction

Frederik CropBart Van RompayeLeen PaelinckLuc VakaetHubert ThierensCarlos De Wagter

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Polymorphisms in nonhomologous end-joining genes associated with breast cancer risk and chromosomal radiosensitivity

Petra WillemsKathleen ClaesAns BaeyensVeerle VandersickelJoke WerbrouckKim De RuyckBruce PoppeRudy Van den BroeckeAmin MakarEmanuela Marras et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Single-nucleotide polymorphisms in DNA double-strand break repair genes: Association with head and neck cancer and interaction with tobacco use and alcohol consumption

Joke WerbrouckKim De RuyckFréderic DuprezMarc Van EijkerenErnst RietzschelSofie BekaertAnne VralWilfried De NeveHubert Thierens

A1 Journal Article in MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The use of [I-123]-2-iodo-L-phenylalanine as an early radiotherapy evaluation tool: In vitro R1M rabdomyosarcoma cell and in vivo mouse experiments

Veerle KersemansValentijn VergoteVirginie de GelderIndira MadaniHubert ThierensWilfried De NeveJ MERTENSGuido SlegersChristian Paul G. BurvenichKathelijne Peremans et al.

A1 Journal Article in CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

mBAND analysis of chromosome aberrations in lymphocytes exposed invitro to alpha-particles and gamma-rays

E JANETCA WHITEHOUSED HOLDSWORTHKim De RuyckKatia VandenbulckeHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

2007

Biologically conformal radiation therapy and Monte Carlo dose calculations in the clinic

Barbara VanderstraetenHubert ThierensWilfried De Neve

Comparison of 6 MV and 18 MV photons for IMRT treatment of lung cancer

Indira MadaniBarbara VanderstraetenS BRALMARC COGHEWerner De GersemCarlos De WagterHubert ThierensWilfried De Neve

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Conversion of CT numbers into tissue parameters for Monte Carlo dose calculations: a multi-centre study

Barbara VanderstraetenPW CHINM FIXA LEALG MORANick ReynaertJ SECOM SOUKUPE SPEZIWilfried De Neve et al.

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Evaluation of pinpoint properties and central electrode material in clinical beam dosimetry by MC calculations

Frederik CropNick ReynaertGEERT PITTOMVILSCarlos De WagterWilfried De NeveLuc VakaetHubert Thierens

Evaluation of uncertainty-based stopping criteria for Monte Carlo calculations of intensity-modulated radiotherapy and arc therapy patient dose distributions

Barbara VanderstraetenAna Maria Luiza OlteanuNick ReynaertA LEALWilfried De NeveHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Implementation of biologically conformal radiation therapy in the clinic

Barbara VanderstraetenWerner De GersemIndira MadaniWilfried De NeveHubert Thierens

Monte Carlo modeling of the ModuLeaf miniature MLC for small field dosimetry and quality assurance of the clinical treatment planning system

Frederik CropNick ReynaertGEERT PITTOMVILSLeen PaelinckWerner De GersemCarlos De WagterLuc VakaetWilfried De NeveHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Polymorphisms in base-excision repair and nucleotide-excision repair genes in relation to lung cancer risk

Kim De RuyckMarcin SzaumkesselIsabelle De RudderANNELORE DEHOORNEAnne VralKathleen ClaesAnja VelgheJan Van MeerbeeckHubert Thierens

A1 Journal Article in MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Positron emission tomography-guided, focal-dose escalation using intensity-modulated radiotherapy for head and neck cancer

Indira MadaniWIM DUTHOYCRISTINA DERIEWerner De GersemTom BoterbergMickey SAERENSFilip JacobsVincent GREGOIREMax LONNEUXLuc Vakaet et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Predicting risk of radiation-induced lung injury

Indira MadaniKim De RuyckH GOEMINNEWilfried De NeveHubert ThierensJan Van Meerbeeck

A1 Journal Article in JOURNAL OF THORACIC ONCOLOGY

TYPETESTING OF PHYSICAL CHARACTERISTICS OF DIGITAL MAMMOGRAPHY SYSTEMS: FIRST EXPERIENCES WITHIN THE FLEMISH BREAST CANCER SCREENING PROGRAMME

Hubert ThierensHilde BosmansNico BulsKlaus BacherAn De HauwereJ JacobsR Clerinx

A1 Journal Article in JBR-BTR

The characterization and transmissibility of chromosome aberrations induced in peripheral blood lymphocytes by in vitro alpha-particle radiation

EJ TAWNCA WHITEHOUSEKim De RuyckL HODGSONKatia VandenbulckeHubert Thierens

A1 Journal Article in RADIATION RESEARCH

The influence of air cavities within the PTV on Monte Carlo-based IMRT optimization

Bart De SmedtBarbara VanderstraetenNick ReynaertWerner De GersemWilfried De NeveHubert Thierens

2006

Accuracy of patient dose calculation for lung IMRT: A comparison of Monte Carlo, convolution/superposition, and pencil beam computations

Barbara VanderstraetenNick ReynaertLeen PaelinckIndira MadaniCarlos De WagterW GERSEMWilfried De NeveHubert Thierens

A1 Journal Article in MEDICAL PHYSICS

Accuracy of patient dose calculations for IMRT treatment of lung cancer

Barbara VanderstraetenNick ReynaertLeen PaelinckIndira MadaniWerner De GersemCarlos De WagterWilfried De NeveHubert Thierens

Assessment of supra-additive effects of cytotoxic drugs and low dose rate irradiation in an in vitro model for hepatocellular carcinoma

Bieke LambertLeo De RidderFilip De VosGuido SlegersVirginie de GelderChristophe Van De WieleHubert Thierens

A1 Journal Article in CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Comparison of dose-volume histograms of IMRT treatment plans for ethmoid sinus cancer computed by advanced treatment planning systems including Monte Carlo

Leen PaelinckBart De SmedtNick ReynaertMARC COGHEWerner De GersemCarlos De WagterBarbara VanderstraetenHubert ThierensWilfried De Neve

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Denoising of Monte Carlo dose calculations: Smoothing capabilities versus introduction of systematic bias

B DE SMEDTM FIPPELNick ReynaertHubert Thierens

A1 Journal Article in MEDICAL PHYSICS

Development of a Monte Carlo dose engine for IMRT treatment planning

Bart De SmedtHubert ThierensCarlos De Wagter

Image quality and radiation dose in digital chest imaging: comparison of an amorphous silicon and amorphous selenium flat-panel system

Klaus BacherPeter SmeetsAn De HauwereTony VoetPhilippe DuyckKoenraad VerstraeteHubert Thierens

Image quality and radiation dose on digital chest imaging: Comparison of amorphous silicon and amorphous selenium flat-panel systems

Klaus BacherPeter SmeetsLudovic VereeckenAn De HauwerePhilippe DuyckR DE MANKoenraad VerstraeteHubert Thierens

A1 Journal Article in AMERICAN JOURNAL OF ROENTGENOLOGY

Image quality performance of LCD devices: influence of display resolution, magnification and window settings on contrast-detail detection

Klaus BacherPeter SmeetsAn De HauwereTony VoetPhilippe DuyckKoenraad VerstraeteHubert Thierens

Image quality performance of liquid crystal display systems: Influence of display resolution, magnification and window settings on contrast-detail detection

Klaus BacherPeter SmeetsAn De HauwereTony VoetPhilippe DuyckKoenraad VerstraeteHubert Thierens

A1 Journal Article in EUROPEAN JOURNAL OF RADIOLOGY

Implementation and validation of an add-on MLC for Monte Carlo dose calculations in conformal stereotactic radiosurgery

Frederik CropNick ReynaertWerner De GersemGEERT PITTOMVILSMARC COGHEWilfried De NeveLuc VakaetHubert Thierens

Implementation of biologically conformal radiation therapy (BCRT) in an algorithmic segmentation-based inverse planning approach

Barbara VanderstraetenWerner De GersemWIM DUTHOYWilfried De NeveHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

In vitro radiosensitivity of peripheral blood lymphocytes in multiple sclerosis patients

I PETCUD SAVUHubert ThierensG NAGELSAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

In vitro screening for synergism of high-linear energy transfer Bi-213-radiotherapy with other therapeutic agents for the treatment of B-Cell chronic lymphocytic leukemia

Katia VandenbulckeHubert ThierensFilip De VosJan PhilippéFritz OffnerAnne JanssensC APOSTOLIDISA MORGENSTERNKlaus BacherVirginie de Gelder et al.

A1 Journal Article in CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

RADIOSTABILITY OF VANCOMYCIN

Samuel BodéElien VangheluweBram BaertN VAN HOOFLuc Van HoorebekeHubert ThierensJean Paul RemonHubert De BrabanderBart De Spiegeleer

Re-188-HDD/lipiodol therapy for hepatocellular carcinoma: an activity escalation study

Bieke LambertKlaus BacherLuc DefreyneHans Van VlierbergheJae Min JeongRong Fu WangJan Van MeerbeeckPeter SmeetsRoberto TroisiHubert Thierens et al.

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

TGF beta 1 polymorphisms and late clinical radiosensitivity in patients treated for gynecologic tumors

Kim De RuyckMarc Van EijkerenKathleen ClaesKlaus BacherAnne VralWilfried De NeveHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

[F-18]fluoro-deoxy-glucose positron emission tomography ([F-18]FDG-PET) voxel intensity-based intensity-modulated radiation therapy (IMRT) for head and neck cancer

Barbara VanderstraetenWIM DUTHOYWerner De GersemWilfried De NeveHubert Thierens

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

2005

Accurate dosimetry: an essential step towards good clinical practice in nuclear medicine

Klaus BacherHubert Thierens

A1 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

Analysis of image quality in digital chest imaging

An De HauwereKlaus BacherPeter SmeetsKoenraad VerstraeteHubert Thierens

A1 Journal Article in RADIATION PROTECTION DOSIMETRY

Chromosomal radio sensitivity of breast cancer with a CHEK2 mutation

Ans BaeyensKathleen ClaesPetra WillemsKim De RuyckHubert ThierensAnne Vral

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

Chromosomal radiosensitivity in breast cancer patients : influence of age of onset of the disease

Ans BaeyensRudy Van den BroeckeAmin MakarHubert ThierensLeo De RidderAnne Vral

A1 Journal Article in ONCOLOGY REPORTS

Conversion of CT numbers into tissue parameters for Monte Carlo dose calculations

Barbara VanderstraetenE BORNM FIPPELA LEALG MORANick ReynaertJ SECOM SOUKUPE SPEZIBart De Smedt et al.

Cytogenetic biodosimetry of an accidental exposure of a radiological worker using multiple assays

Hubert ThierensKim De RuyckAnne VralVirginie de GelderCA WHITEHOUSEFJ TAWNI BOESMAN

A1 Journal Article in RADIATION PROTECTION DOSIMETRY

Decoupling initial electron beam parameters for Monte Carlo photon beam modelling by removing beam-modifying filters from the beam path

Bart De SmedtNick ReynaertF FLACHETMARC COGHEMG THOMPSONLeen PaelinckGEERT PITTOMVILSCarlos De WagterWilfried De NeveHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Effects of estradiol and progesterone on the variability of the micronucleus assay

Ans BaeyensVeerle VandersickelHubert ThierensLeo De RidderAnne Vral

A1 Journal Article in MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Experimental verification of lung dose with radiochromic film: comparison with Monte Carlo simulations and commercially available treatment planning systems

Leen PaelinckNick ReynaertHubert ThierensWilfried De NeveCarlos De Wagter

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

IMRT dose distributions for ethmoid sinus cancer calculated by five different treatment planning systems

Leen PaelinckBart De SmedtNick ReynaertMARC COGHEWerner De GersemCarlos De WagterBarbara VanderstraetenHubert ThierensWilfried De Neve

In vitro chromosomal radiosensitivity in breast cancer patients

Ans BaeyensAnne VralHubert Thierens

In vivo evaluation and dosimetry of I-123-2-iodo-D-phenylalanine, a new potential tumor-specific tracer for SPECT in an R1M rhabdomyrosarcoma athymic mouse model

Veerle KersemansBart CornelissenKlaus BacherK KERSEMANSHubert ThierensRudi DierckxBart De SpiegeleerGuido SlegersJ MERTENS

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Investigation of geometrical and scoring grid resolution for Monte Carlo dose calculations for IMRT

Bart De SmedtBarbara VanderstraetenNick ReynaertWilfried De NeveHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Microsatellite polymorphisms in DNA repair genes XRCC1, XRCC3 and XRCC5 in patients with gynecological tumors: Association with late clinical radiosensitivity and cancer incidence

Kim De RuyckCS WILDINGMarc Van EijkerenR MORTHIEREJ TAWNHubert Thierens

A1 Journal Article in RADIATION RESEARCH

New strategies in radionuclide therapy for hepatocellular carcinoma

Bieke LambertChristophe Van De WieleHubert Thierens

Optimised tracer-dependent dosage cards to obtain weight-independent effective doses

Filip JacobsHubert ThierensA PIEPSZKlaus BacherChristophe Van De WieleHamphrey HamRudi Dierckx

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Optimization of the mean energy of the incident electron beam for MCTP by removing the beam-modifying filters from the linac head

Bart De SmedtNick ReynaertFemke FlachetMARC COGHELeen PaelinckGEERT PITTOMVILSJ SCHAUVLIEGECarlos De WagterWilfried De NeveHubert Thierens

Osteopontin and bone metabolism: a histology and scintigraphy study in rats

Madjid GordjestaniLuc DermautLeo De RidderHubert ThierensP De WaeleW De Leersnijder WillyF Bosman

A1 Journal Article in INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Patient dosimetry in radionuclide therapy: the whys and the wherefores

Hubert ThierensMyriam MonsieursKlaus Bacher

A1 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

Patient-specific dose and radiation risk estimation in pediatric cardiac catheterization

Klaus BacherEvelien BogaertRégine LapereDaniël De WolfHubert Thierens

A1 Journal Article in CIRCULATION

Pulsatile tinnitus and the intrameatal vascular loop: Why do we not hear our carotids?

D DE RIDDERLeo De RidderV NOWEHubert ThierensP VAN DE HEYNINGA MOLLER

A1 Journal Article in NEUROSURGERY

Radiation-induced damage to normal tissues after radiotherapy in patients treated for gynecologic tumors: Association with single nucleotide polymorphisms in XRCC1, XRCC3, and OGG1 genes and in vitro chromosomal radiosensitivity in lymphocytes

Kim De RuyckMarc Van EijkerenKathleen ClaesR MORTHIERAnne De PaepeAnne VralLeo De RidderHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Re-188-HDD/Lipiodol therapy for hepatocellular carcinoma: a phase I clinical trial

Bieke LambertKlaus BacherLuc DefreyneFilip GemmelHans Van VlierbergheJae Min JeongRudi DierckxChristophe Van De WieleHubert ThierensFilip De Vos

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Re-188-HDD/lipiodol for treatment of hepatocellular carcinoma: A feasibility study in patients with advanced cirrhosis

BIEKE LAMBERTKlaus BacherKATRIEN DE KEUKELEIREPeter SmeetsIsabelle ColleJM JEONGHubert ThierensRoberto TroisiFilip De VosChristophe Van De Wiele

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

The effect of geometrical and scoring voxel dimensions on accuracy and efficacy of Monte Carlo dose calculations for IMRT

Bart De SmedtBarbara VanderstraetenNick ReynaertWilfried De NeveHubert Thierens

The importance of accurate linear accelerator head modelling for IMRT Monte Carlo calculations

Nick ReynaertMARC COGHEBart De SmedtLeen PaelinckBarbara VanderstraetenWerner De GersemBART VAN DUYSECarlos De WagterWilfried De NeveHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

2004

Are genetic polymorphisms in OGG1, XRCC1 and XRCC3 genes predictive for the DNA strand break repair phenotype and genotoxicity in workers exposed to low dose ionising radiations?

P AKAR MATEUCAJP BUCHETHubert ThierensM KIRSCH-VOLDERS

A1 Journal Article in MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Biodistribution and dosimetry of Tc-99m-depreotide (P829) in patients suffering from breast carcinoma

BIEKE VAN DEN BOSSCHEE D'HAENINCKKlaus BacherHubert ThierensSimon Van BelleRudi DierckxChristophe Van De Wiele

A1 Journal Article in CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Biologic dosimetry of Re-188-HDD/lipiodol versus I-131-lipiodol therapy in patients with hepatocellular carcinoma

Kim De RuyckBieke LambertKlaus BacherF GEMMELFILIP DE VOSAnne VralLeo De RidderRudi DierckxHubert Thierens

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Chromosomal aberrations and in vitro radiosensitivity: intra-individual versus inter-individual variability

Anne VralHubert ThierensAns BaeyensLeo De Ridder

A1 Journal Article in TOXICOLOGY LETTERS

Chromosomal radiosensitivity in BRCA1 and BRCA2 mutation carriers

Ans BaeyensHubert ThierensKathleen ClaesBruce PoppeLeo De RidderAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Chromosomal radiosensitivity in secondary-progressive multiple sclerosis patients

Ileana PetcuDiana SavuAnne VralHubert ThierensGuy NagelsLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Comparison of the real-life radiation burden to relatives of patients treated with I-131-Lipiodol or Re-188-HDD/Lipiodol

Klaus BacherBieke LambertFilip De VosChristophe Van De WieleRudi DierckxHubert Thierens

DOSSCORE: An accelerated DOSXYZnrc code with an efficient stepping algorithm and scoring grid

Bart De SmedtNick ReynaertHubert ThierensWilfried De Neve

DOSSCORE: an accelerated DOSXYZnrc code with an efficient stepping algorithm and scoring grid

Bart De SmedtNick ReynaertWilfried De NeveHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Development, pharmaceutical validation and radioprotection properties of a new concept of 188W/188Re generator

Filip De VosM De DeckerKlaus BacherBieke LambertB DavidHubert ThierensGuido SlegersRudi Dierckx

Importance of receptor density in alpha radioimmunotherapy in B cell malignancies: an in-vitro study

Katia VandenbulckeHubert ThierensFritz OffnerAnne JanssensVirginie de GelderKlaus BacherJan PhilippéFilip De VosRudi DierckxC APOSTOLIDIS et al.

A1 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

Incorporation of biological imaging voxel intensity information into the IMRT optimization algorithm

Barbara VanderstraetenWerner De GersemWim DuthoyWilfried De NeveHubert Thierens

MCDE: a new Monte Carlo dose engine for IMRT

Nick ReynaertBart De SmedtMARC COGHELeen PaelinckBART VAN DUYSEWerner De GersemCarlos De WagterWilfried De NeveHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Patient doses in gamma-intracoronary radiotherapy: The radiation burden assessment study

Hubert ThierensNick ReynaertKlaus BacherMarc Van EijkerenYvo Taeymans

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Radiolabeling, biodistribution, and dosimetry of I-123-mAb 14C5: A new mAb for radioimmunodetection of tumor growth and metastasis in vivo

CMM LAHORTEKlaus BacherIngrid BurvenichElisabeth CoeneClaude CuvelierC DE POTTERHubert ThierensChristophe Van De WieleRudi DierckxGuido Slegers

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Screening for supra-additive effects of cytotoxic drugs and gamma irradiation in an in vitro model for hepatocellular carcinoma

Bieke LambertLeo De RidderGuido SlegersVirginie de GelderRudi DierckxHubert Thierens

A1 Journal Article in CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

The use of EBV-transformed cell lines of breast cancer patients to measure chromosomal radiosensitivity

Ans BaeyensHubert ThierensKatia VandenbulckeLeo De RidderAnne Vral

A1 Journal Article in MUTAGENESIS

The use of IL-2 cultures to measure chromosomal radiosensitivity in breast cancer patients

Ans BaeyensKatia VandenbulckeJan PhilippéHubert ThierensLeo De RidderAnne Vral

A1 Journal Article in MUTAGENESIS

2003

Alpha-immunotherapy compared to external gamma irradiation, cold antibody and chemotherapy in B-CLL in vitro: Correlation with clinical chemotherapy sensitivity

K VANDENBULCKEFritz OffnerFilip De VosA JANSSENST NIKULAC APOSTOLIDESR MOLINETW JANSSENSHubert ThierensRudi Dierckx et al.

Biodistribution and dosimetry study of I-123-rh-annexin V in mice and humans

CMM LAHORTEChristophe Van De WieleKlaus BacherBIEKE VAN DEN BOSSCHEHubert ThierensSimon Van BelleG SLEGERSRudi Dierckx

A1 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

Cold and alpha-conjugated anti-CD20 induce different in vitro apoptosis reponses in B-chronic lymphocytic leukaemia (B-CLL)and splenic lymphoma with villous lymphocytes (SLVL)

K VANDENBULCKEFritz OffnerGuido SlegersFilip De VosVirginie de GelderA WILLEMSS MARTINR MOLINETC APOSTOLIDISTK NIKULA et al.

Cytotoxicity of gamma versus alpha radiation in lymphoid cell lines with defects in the TNF receptor family mediated and NF-kappa B related apoptotic and anti-apoptotic pathways

KJ VANDENBULCKEK VANDENBULCKERudi BeyaertC APOSTOLIDEST NIKULAW JANSSENSANN JANSSENSVirginie de GelderAnnick WillemsGuido Slegers et al.

Dose reduction in patients undergoing chest imaging: Digital amorphous silicon flat-panel detector radiography versus conventional film-screen radiography and phosphor-based computed radiography

Klaus BacherPeter SmeetsAn De HauwereKoenraad VerstraeteHubert Thierens

A1 Journal Article in AMERICAN JOURNAL OF ROENTGENOLOGY

In vitro evaluation of Bi-213-rituximab versus external gamma irradiation for the treatment of B-CLL patients: Relative biological efficacy with respect to apoptosis induction and chromosomal damage by the micronucleus assay

K VANDENBULCKEFilip De VosFritz OffnerJan PhilippéC APOSTOLIDISR MOLINETTK NIKULAKlaus BacherVirginie de GelderAnne Vral et al.

In vitro evaluation of Bi-213-rituximab versus external gamma irradiation for the treatment of B-CLL patients: relative biological efficacy with respect to apoptosis induction and chromosomal damage

Katia VandenbulckeFILIP DE VOSFritz OffnerJan PhilippéC APOSTOLIDISR MOLINETTK NIKULAKlaus BacherV DE GELDERAnne Vral et al.

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Intra-arterial radionuclide therapy for liver tumours: effect of selectivity of catheterization and 131I-lipiodol delivery on tumour uptake and response

B BransKlaus BacherVincent VandevyverPeter VanlangenhovePeter SmeetsHubert ThierensRudi DierckxLuc Defreyne

A1 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

Introduction of scoregrids into a Monte-Carlo based treatment planning system

Nick ReynaertBart De SmedtHubert ThierensMARC COGHECarlos De WagterWilfried De Neve

Monte Carlo model of the Elekta SLiplus accelerator: validation of a new MLC component module in BEAM for a 6 MV beam

J VAN DE WALLEC MARTENSNick ReynaertH PALMANSMARC COGHEWilfried De NeveCarlos De WagterHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Patient dosimetry for I-131-lipiodol therapy

Myriam MonsieursKlaus BacherB BRANSAnne VralLeo De RidderRudi DierckxHubert Thierens

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

The necessity of a divergent initial electron beam in the Monte-Carlo model of a linear accelerator

Bart De SmedtNick ReynaertMARC COGHELeen PaelinckB VAN DUYSSECarlos De WagterWilfried De NeveHubert Thierens

The value of radiochromic film dosimetry around air cavities: experimental results and Monte Carlo simulations

Leen PaelinckNick ReynaertHubert ThierensCarlos De WagterWilfried De Neve

The value of radiochromic film dosimetry around air cavities: experimental results and Monte Carlo simulations

Leen PaelinckNick ReynaertHubert ThierensCarlos De WagterWilfried De Neve

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Use of a calcium phosphate matrix as a temporary cast for bony defect repair: a pilot study

A ROELSMaria CornelissenEAP DE MAEYERHubert ThierensRonald VerbeeckLuc Dermaut

A1 Journal Article in JOURNAL OF MATERIALS SCIENCE

2002

Absorbed dose to water based dosimetry versus air kerma based dosimetry for high-energy photon beams: an experimental study.

H PALMANSL NAFAAJ DE JANSS GILLISMT HOORNAERTC MARTENSM PIESSENSHubert ThierensA VAN DER PLAETSENS VYNCKIER

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Alpha-immunotherapy compared to gamma-radiation, cold antibody, and chemotherapy in B-CLL in vitro: Correlation with clinical chemosensitivity

Fritz OffnerKL VANDENBULCKEF DEVOSANN JANSSENSJan PhilippéGuido SlegersHubert ThierensT NIKULAC APOSTOLIDESW JANSSENS et al.

Assessment of genotoxic effects related to chronic low level exposure to ionizing radiation using biomarkers for DNA damage and repair

N TouilP Vande AkaJP BuchetHubert ThierensM Kirsch-Volders

A1 Journal Article in MUTAGENESIS

Chromosomal radiosensitivity in breast cancer patients with a known or putative genetic predisposition

Ans BaeyensHubert ThierensKathleen ClaesBruce PoppeLudwine MessiaenLeo De RidderAnne Vral

A1 Journal Article in BRITISH JOURNAL OF CANCER

Chromosomal radiosensitivity study of temporary nuclear workers and the support of the adaptive response induced by occupational exposure.

Hubert ThierensAnne VralM BARBEM MEIJLAERSAns BaeyensLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Digital amorphous silicon flat-panel detector vs screen-film and storage phosphor systems in chest imaging: Comparison of the entrance skin dose

Peter SmeetsKlaus BacherPhilippe DuyckKoenraad VerstraeteHubert Thierens

Dose distributions for Y-90 intravascular brachytherapy sources used with balloon catheters.

M PIESSENSNick ReynaertJ POTEMPAHubert ThierensW WIJNSL VERBEKE

A1 Journal Article in MEDICAL PHYSICS

Induction and disappearance of G2 chromatid breaks in lymphocytes after low doses of low-LET gamma-rays and high-LET fast neutrons.

Anne VralHubert ThierensAns BaeyensLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Interphase death in human peripheral blood lymphocytes after moderate and high doses of low and high LET radiation: an electron microscopic approach

Maria CornelissenHubert ThierensLeo De Ridder

A1 Journal Article in ANTICANCER RESEARCH

Micronucleus assay reveals no radiation effects among nuclear power plant workers.

Hubert ThierensAnne VralM BARBELeo De Ridder

A1 Journal Article in HEALTH PHYSICS

Parameter dependence of the MCNP electron transport in determining dose distributions.

Nick ReynaertHugo PalmansHubert ThierensR JERAJ

A1 Journal Article in MEDICAL PHYSICS

Patient dose reduction with a digital amorphous silicon flat panel detector compared to conventional screen-film and phosphor-based computed radiography systems in chest imaging

Klaus BacherPV SMEETSA DE HAUWEREKoenraad VerstraeteHubert Thierens

Patient dosimetry for 131I-MIBG therapy for neuroendocrine tumors based on 123I-MIBG scans.

M MONSIEURSB BRANSKlaus BacherRudi DierckxHubert Thierens

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Patient-specific Monte Carlo calculation of the effective dose in pediatric interventional cardiology

Klaus BacherI SEAUXDaniël De WolfHubert Thierens

The micronucleus and G(2)-phase assays for human blood lymphocytes as biomarkers of individual sensitivity to ionizing radiation: Limitations imposed by intraindividual variability.

Anne VralHubert ThierensAns BaeyensLeo De Ridder

A1 Journal Article in RADIATION RESEARCH

Thyroid uptake and radiation dose after (131)I-lipiodol treatment: is thyroid blocking by potassium iodide necessary?

Klaus BacherB BransMyriam MonsieursF De WinterRudi DierckxHubert Thierens

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Thyroidal uptake and radiation dose after repetitive I-131-MIBG treatments: Influence of potassium iodide for thyroid blocking.

B BRANSMyriam MonsieursGenevieve LaureysJean KaufmanHubert ThierensRudi Dierckx

A1 Journal Article in MEDICAL AND PEDIATRIC ONCOLOGY

Toepassingen van de radionuclidentherapie: radiofarmaca, werkingsmechanismen en stralingsbescherming

B BRANSMyriam MonsieursKlaus BacherF DE VOSHubert ThierensGuido SlegersRudi Dierckx

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Towards a standardization of biological dosimetry by cytogenetics.

P VOISINF BARQUINEROB BLAKELYC LINDHOLMD LLOYDC LUCCIONIS MILLERF PALITTIP PRASANNAG STEPHAN et al.

A1 Journal Article in CELLULAR AND MOLECULAR BIOLOGY

Underdosage of the upper-airway mucosa for small fields as used in intensity-modulated radiation therapy: A comparison between radiochromic film measurements, Monte Carlo simulations, and collapsed cone convolution calculations.

Chantal MartensNick ReynaertCarlos De WagterP NILSSONMARC COGHEH PALMANSHubert ThierensWilfried De Neve

A1 Journal Article in MEDICAL PHYSICS

2001

131I-Lipiodol therapy: influence of potassiumiodide on thyroidal uptake and dose

Klaus BacherB BransRoberto TroisiMyriam MonsieursLuc DefreynePeter VanlangenhoveIsabelle ColleBernard de HemptinneHubert ThierensRudi Dierckx

188-Re-lipiodol: Prediction of the patient dose based on 131-I-lipiodol bi-planar scanning and Monte-Carlo simulation

Klaus BacherHubert ThierensS VAN DE PUTTEB BRANSMyriam MonsieursRudi Dierckx

A critical discussion of the 2nd intercomparison on electron paramagnetic resonance dosimetry with tooth enamel.

Gauthier VanhaelewynSami AmiraR DEBUYSTFreddy CallensT GLORIEUXG LELOUPHubert Thierens

A1 Journal Article in RADIATION MEASUREMENTS

A higher micronucleus yield in B- versus T-cells after low-dose gamma-irradiation is not linked with defective Ku86 protein.

Anne VralHubert ThierensP BRYANTLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Biodistribution and dosimetry of Tc-99m-RP527, a gastrin-releasing peptide (GRP) agonist for the visualization of GRP receptor-expressing malignancies

C Van De WieleFilip DumontRudi DierckxSH PeersJ ThornbackG SleghersHubert Thierens

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Comparison of in vitro apoptosis induction by alpha-irradiation versus gamma-irradiation in B-CLL

Fritz OffnerFilip De VosK VANDENBULCKEANN JANSSENSR MOLINETC APOSTOLIDISW JANSSENST NIKULAChristophe LahorteB BRANS et al.

Dosimetry from organ to cellular dimensions.

Hubert ThierensMA MONSIEURSB BRANST VAN DRIESSCHEI CHRISTIAENSRudi Dierckx

A1 Journal Article in COMPUTERIZED MEDICAL IMAGING AND GRAPHICS

Dosimetry of 192Ir sources used for endovascular brachytherapy

Nick ReynaertMarc Van EijkerenYvo TaeymansHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Experimental p(wall) and p(cel) correction factors for ionization chambers in low-energy clinical proton bearras.

Hugo PalmansFrans VerhaegenJM DENISS VYNCKIERHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Patient dosimetry after I-131-MIBG therapy for neuroblastoma and carcinoid tumours.

MA MONSIEURSHubert ThierensAnne VralB BRANSLeo De RidderRudi Dierckx

A1 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

Translocation frequencies measured in patients one year after radioactive iodine therapy for thyrotoxicosis.

V LAMBERTHubert ThierensM MONSIEURSC RONCANCIOC LAURENT

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

2000

Adaptive response in patients treated with 131I.

MA MONSIEURSHubert ThierensAnne VralC VAN DE WIELELeo De RidderRudi Dierckx

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

An organotypical in vitro model for vascular tissue remodelling and its application to study radiation effects.

M VERBEKEHubert ThierensYvo TaeymansLeo De Ridder

A1 Journal Article in CYTOTECHNOLOGY

Analysis of chromosome loss and chromosome segregation in cytokinesis-blocked human lymphocytes: non-disjunction is the prevalent mistake in chromosome segregation produced by low dose exposure to ionizing radiation.

N TOUILA ELHAJOUJIHubert ThierensM KIRSCH-VOLDERS

A1 Journal Article in MUTAGENESIS

Biodistribution and dosimetry of [I-123]iodo-PK 11195: a potential agent for SPET imaging of the peripheral benzodiazepine receptor

JAN VersijptFilip DumontHubert ThierensHugo JansenFilip De VosG SlegersPatrick SantensRudi DierckxJ Korf

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE

Biomonitoring of radiation workers in Belgium : results of large scale cytogenetic studies using the micronucleus-centromere assay

Hubert ThierensAnne VralB AousalahM BarbéR MorthierLeo De Ridder

Co-57-EDTA renal imaging in rats.

C VAN DE WIELEP GOETHALSA VOLKAERTF DE WINTERHubert ThierensRudi Dierckx

A1 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

Correlation of patient skin doses in cardiac interventional radiology with dose-area product.

Sascha Van De PutteF VERHAEGENYvo TaeymansHubert Thierens

A1 Journal Article in BRITISH JOURNAL OF RADIOLOGY

Cytogenetic monitoring of hospital workers occupationally exposed to ionizing radiation using the micronucleus centromere assay

Hubert ThierensAnne VralR MorthierB AousalahLeo De Ridder

A1 Journal Article in MUTAGENESIS

In vitro apoptosegevoeligheid van B-cel chronische lymfatische leukemie-lymfocyten en hun moleculair-biologische kenmerken

G Van CausbroeckA JanssensW Vanden BergheHubert ThierensG HaegemanJan Philippé

A4 Journal Article in TIJDSCHRIFT VAN DE BELGISCHE VERENIGING VAN LABORATORIUM-TECHNOLOGEN = REVUE DE L'ASSOCIATION BELGE DES TECHNOLOGUES DE LABORATOIRE

Verification of the absorbed dose values determined with plane parallel ionization chambers in therapeutic electron beams using ferrous sulphate dosimetry.

Ann Van Der PlaetsenHubert ThierensHugo Palmans

1999

57Co-ETDA renal imaging in rats

Christophe Van De WielePatrick GoethalsA VOLKAERTF DE WINTERHubert ThierensRudi Dierckx

A cytogenetic study of nuclear power plant workers using the micronucleus-centromere assay.

Hubert ThierensAnne VralM BARBEB AOUSALAHLeo De Ridder

A1 Journal Article in MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

A multidisciplinary approach to the healing of cranial and residual maxillary cleft defects by means of allogenous demineralized osseous implants and polylactic acid casts in dogs.

Martinus KuylHubert ThierensLuc DermautLeo De Ridder

A1 Journal Article in CLEFT PALATE-CRANIOFACIAL JOURNAL

Absorbed dose beam quality correction factors k(Q) for the NE2571 chamber in a 5 MV and a 10 MV photon beam.

Hugo PalmansWilly MondelaersHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Apoptosis induced by γ irradiation in peripheral blood mononuclear cells is not mediated by cytochrome-c release and only partially involves caspase-3-like proteases

Henk LouagiePeter SchotteAnne VralMaria CornelissenHubert ThierensRudi BeyaertLeo De RidderJan Philippé

A1 Journal Article in CELL BIOLOGY INTERNATIONAL

Biodistribution and dosimetry of (iodine-123)-iodomethyl-N,N-diethyltamoxifen, an (anti)oestrogen receptor radioligand.

Christophe Van De WieleFilip De VosJohan De SutterFilip DumontG SLEGERSRudi DierckxHubert Thierens

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE

Changes in peripheral blood lymphocyte subsets in patients undergoing radiotherapy.

Henk LouagieMarc Van EijkerenJan PhilippéHubert ThierensLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Cytogenetische studies bij patiënten behandeld met 131I-Nal voor schildklieraandoeningen of 131I-MIBG voor neuroblastoma

Myriam MonsieursHubert ThierensAnne VralChristophe Van De WieleLeo De RidderRudi Dierckx

A2 Journal Article in TIJDSCHRIFT VOOR NUCLEAIRE GENEESKUNDE

Dose measurements compared with Monte Carlo simulations of narrow 6 MV multileaf collimator shaped photon beams.

K DE VLAMYNCKH PALMANSF VERHAEGENCarlos De WagterWilfried De NeveHubert Thierens

A1 Journal Article in MEDICAL PHYSICS

Estimation of risk based on biological dosimetry for patients treated with radioiodine.

Myriam MonsieursHubert ThierensChristophe Van De WieleAnne VralIA MEIRLAENHilde De WinterCJ DE SADELEERLeo De RidderJean KaufmanRudi Dierckx

A1 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

Inter-laboratory comparison of cytogenetic endpoints for the biomonitoring of radiological workers.

Hubert ThierensAnne VralLeo De RidderN TOUILM KIRSCH-VOLDERSV LAMBERTC LAURENT

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Monte Carlo calculations of dose distributions around 32P and 198Au stents for intravascular brachytherapy

Nick ReynaertF VerhaegenYvo TaeymansMarc Van EijkerenHubert Thierens

A1 Journal Article in MEDICAL PHYSICS

Status report from Belgium: Analysis of the TRS-381 code of practice - verification of the absorbed dose values determined with plane-parallel ionisation chambers in therapeutic electron beams using ferrous sulphate dosimetry.

Ann Van Der PlaetsenHugo PalmansHubert Thierens

A4 Journal Article in SSDL Newsletters (Vienna : IAEA)

The effect of caspase-inhibitors on radiation induced apoptosis in human peripheral blood lymphocytes: an electron microscopic approach

Maria CornelissenAnne VralHubert ThierensLeo De Ridder

A1 Journal Article in APOPTOSIS

The life span of the BD-PND bubble detector.

F VANHAVEREM LOOSHubert Thierens

A1 Journal Article in RADIATION PROTECTION DOSIMETRY

1998

A combined use of the BD-PND and BDT bubble detectors in neutron dosimetery.

F VANHAVEREM LOOSAJM PLOMPENE WATTECAMPSHubert Thierens

A1 Journal Article in RADIATION MEASUREMENTS

Apoptosis induced by fast neutrons versus Co-60 gamma-rays in human peripheral blood lymphocytes

Anne VralMaria CornelissenHubert ThierensHenk LouagieJan PhilippéKarel StrijckmansLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Biodistribution and dosimetry of carbon-11-methoxyprogabidic acid, a possible ligand for GABA-receptors in the brain.

Patrick SantensFilip De VosHubert ThierensD DECOOGuido SlegersRudi DierckxJacques De Reuck

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Flow cytometric scoring of apoptosis compared to electron microscopy in γ irradiated lymphocytes

Henk LouagieMaria CornelissenJan PhilippéAnne VralHubert ThierensLeo De Ridder

A1 Journal Article in CELL BIOLOGY INTERNATIONAL

In water calibration of PDR 192Ir brachytherapy sources with an NE2571 ionization chamber

Nick ReynaertFrans VerhaegenHubert Thierens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Inductie van micronuclei apoptose in natural killer cellen in vergelijking met T lymfocyten na γ-bestraling

L LouagieJan PhilippéAnne VralMaria CornelissenHubert ThierensLeo De Ridder

A4 Journal Article in TIJDSCHRIFT VAN DE BELGISCHE VERENIGING VAN LABORATORIUM-TECHNOLOGEN = REVUE DE L'ASSOCIATION BELGE DES TECHNOLOGUES DE LABORATOIRE

Induction of micronuclei and apoptosis in natural killer cells compared to T lymphocytes after gamma-irradiation.

H LOUAGIEJan PhilippéAnne VralMaria CornelissenHubert ThierensI DE RIDDER

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Micronucleus frequencies in cytokinesis-blocked human B lymphocytes after low dose gamma-irradiation.

Anne VralHenk LouagieHubert ThierensJan PhilippéMaria CornelissenLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Real-life radiation burden to relatives of patients treated with iodine-131: a study in eight centres in Flanders (Belgium).

M MONSIEURSHubert ThierensRudi DierckxK CASIERE DE BAERELeo De RidderC DE SAEDELEERHilde De WinterM LIPPENSS VAN IMSCHOOT et al.

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE

1997

Flow cytometry as a quantitative and sensitive method to evaluate low dose radiation induced apoptosis in vitro in human peripheral blood lymphocytes

Koen HertveldtJan PhilippéHubert ThierensMaria CornelissenAnne VralLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

In vitro micronucleus-centromere assay to detect radiation-damage induced by low doses in human lymphocytes

Anne VralHubert ThierensLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Quantification of apoptosis in lymphocyte subsets and effect of apoptosis on apparent expression of membrane antigens

Jan PhilippéHenk LouagieHubert ThierensAnne VralMaria CornelissenLeo De Ridder

A1 Journal Article in CYTOMETRY

Relationschip of decreased chemotaxis of technetium-99-m-HMPAO-labeled lymphocytes to apoptosis

Christophe Van De WieleJan PhilippéJP VAN HAELSTJozef Van DammeHubert ThierensGeert Leroux-RoelsRudi Dierckx

A2 Journal Article in Journal Nuclear Medicine, nr. 38, pp. 1417-1421, 2 figg

Relationship of decreased chemotaxis of technetium-99m-HMPAO-labeled lymphocytes to apoptosis

C Van de WieleJan PhilippéJP Van HaelstJozef Van DammeHubert ThierensGeert Leroux-RoelsRudi Dierckx

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Semi-automated micronucleus scoring in cytokinesis-blocked lymphocytes after irradiation

Hubert ThierensAnne VralF De ScheerderLeo De RidderA Tates

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

1996

A cytogenetic study of radiological workers: effect of age, smoking and radiation burden on the micronucleus frequency

Hubert ThierensAnne VralLeo De Ridder

A1 Journal Article in MUTATION RESEARCH-ENVIRONMENTAL MUTAGENESIS AND RELATED SUBJECTS

Effects of ionizing radiation on cartilage: emphasis on the extracellular matrix

Maria CornelissenHubert ThierensLeo De Ridder

A2 Journal Article in SCANNING MICROSCOPY

Kinetics of [methyl-C-11]thymidine in patients with squamous cell carcinoma of the head and neck

ME VANEIJKERENHubert ThierensJ SEUNTJENSPatrick GoethalsIgnace LemahieuKarel Strijckmans

A1 Journal Article in ACTA ONCOLOGICA

Mechanism of age-dependent involution in embryonic chick notochords

E GhanemMaria CornelissenHubert ThierensLeo De Ridder

A1 Journal Article in EXPERIENTIA

Methyl-11 C Thymidine for in Vivo Measurement of Cell Proliferation

P GOETHALSNorbert LameireM VAN EIJKEREND KESTELOOTHubert ThierensR DAMS

A2 Journal Article in J. Nuclear Med., 37, n° 6, pp. 1048-1052

Micronucleus induction by 60Co γ-rays and fast neutrons in ataxia telangiectasia lymphocytes

Anne VralHubert ThierensLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Optimalisatie van de in vitro micronucleus methode voor humane lymfocyten via in situ hybridisatie met een centromeer probe

Anne VralHubert ThierensLeo De Ridder

Water calorimetry and ionization chamber dosimetry in an 85-MeV clinical proton beam.

H PALMANSJ SEUNTJENSF VERHAEGENJM DENISS VYNCKIERHubert Thierens

A1 Journal Article in MEDICAL PHYSICS

Water calorimetry measurements in a 85 MeV clinical proton beam

H PALMANSJan SeuntjensFrans VerhaegenJM DENISS VYNCKIERHubert Thierens

A2 Journal Article in Bull. Cancer/Radiother., 83(Suppl 1) pp.l76s-178s, 1996

[Methyl-carbon-11]thymidine for in vivo measurement of cell proliferation

Patrick GoethalsNorbert LameireM VANEIJKEREND KESTELOOTHubert ThierensRichard Dams

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

1995

A Study of Ion Chamber Response Compared with Water Calorimetry in a Clinical 85 MeV Proton Beam

H PALMANSJan SeuntjensFrans VerhaegenJ DENISS VYNCKIERHubert Thierens

A2 Journal Article in Radiotherapy and Oncology, 37, 1995 (suppl. 1), p. S44

Characteristics of creatine release during acute myocardial-infarction, unstable angina and cardiac-surgery.

Joris DelangheMarc De BuyzereIK DESCHEERDERLP CLUYSEHubert Thierens

A1 Journal Article in CLINICAL CHEMISTRY

Micronucleus induction in peripheral blood lymphocytes of patients under radiotherapy treatment for cervical cancer or Hodgkin's disease.

Hubert ThierensAnne VralMarc Van EijkerenFranki SpelemanLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Water Calorimetry for Clinical Proton Beams

Jan SeuntjensH PALMANSFrans VerhaegenJ DENISS VYNCKIERHubert Thierens

1994

2ND EUROMET COMPARISON OF AIR KERMA RATE AND ACTIVITY MEASUREMENTS OF IR-192 BRACHYTHERAPY WIRES.

DFG REHERAHL AALBERSH BJERKEN DRUGGET GENKAMJ ROSSITERD SANTRYJP SEPHTONG SIBBENSJ SEUNTJENS et al.

A1 Journal Article in NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT

Biokinetics and dosimetry for [methyl-11C] thymidine

Hubert ThierensM VANEIJKERENPatrick Goethals

A1 Journal Article in BRITISH JOURNAL OF RADIOLOGY

COMPARISON OF MEASURED AND CALCULATED DOSE DISTRIBUTIONS IN LUNG AFTER ELECTRON-BEAM TREATMENT OF THE CHEST-WALL.

J SEUNTJENSA VANDERPLAETSENHubert ThierensM PIESSENS

A1 Journal Article in MEDICAL PHYSICS

Dose-response curve of the effects of serotonin and ketanserin on the functional morphology of skin in vitro

Hilde BeeleHubert ThierensLeo De Ridder

A1 Journal Article in SKIN PHARMACOLOGY

EMISSION OF ALPHA-PARTICLES DURING THE SPONTANEOUS FISSION OF PU-244.

M VERBOVENEtienne JacobsD DEFRENNEHubert ThierensP DHONDT

A1 Journal Article in PHYSICAL REVIEW C-NUCLEAR PHYSICS

INFRARED-LASER AND BONE METABOLISM - A PILOT-STUDY.

M GORDJESTANILuc DermautHubert Thierens

A1 Journal Article in INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Micronuclei induced by fast-neutrons versus 60Co γ-rays in human peripheral blood lymphocytes

Anne VralFrans VerhaegenHubert ThierensLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Scoring of radiation-induced micronuclei in cytokinesis-blocked human lymphocytes by automated image analysis

Frans VerhaegenAnne VralJ SeuntjensNW SchipperLeo De RidderHubert Thierens

A1 Journal Article in CYTOMETRY

Study of correction factors and the relative heat defect of a water calorimetric determination of absorbed dose to water in high energy photon beams

Jan SeuntjensAnn Van Der PlaetsenKoenraad Van LaereHubert Thierens

The in vitro cytokinesis-block micronucleus assay : a detailed description of an improved slide preparation technique for the automated detection of micronuclei in human lymphocytes.

Anne VralFrans VerhaegenHubert ThierensLeo De Ridder

A1 Journal Article in MUTAGENESIS

Verification of absorbed doses determined with thimble and parallel-plate ionization chambers in clinical electron-beams using ferrous sulphate dosimetry.

A VANDERPLAETSENJ SEUNTJENSHubert ThierensS VYNCKIER

A1 Journal Article in MEDICAL PHYSICS

1993

Calculation of acute myocardial infarction size making use of cumulative myoglobin release in serum

Joris DelangheMarc De BuyzereLP CLUYSEHubert ThierensDenis Clement

A2 Journal Article in Eur. J. Clin. Chem. Clin. Biochem. (1992) 30: pp 823-830, 2 figg., 4 tabb

Correction factors for a cylindrical ionisation chamber used in medium-energy x-ray beams.

J SEUNTJENSHubert ThierensU SCHNEIDER

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Effects of ionizing radiation on the size distribution of proteoglycan aggregates synthesized by chondrocytes in agarose

Maria CornelissenHubert ThierensLeo De Ridder

A1 Journal Article in SCANNING MICROSCOPY

Radiation damage to endothelial cells in vitro, as judged by micronucleus assay

M RaicuAnne VralHubert ThierensLeo De Ridder

A1 Journal Article in MUTAGENESIS

Radiation effects on the matrix synthesis in non-ossifying embryonic cartilage in vitro: a functional and morphological study

Maria CornelissenHubert ThierensLeo De Ridder

A1 Journal Article in TISSUE & CELL

Study of the relative heat-defect and correction factors of a water calo-rimetric determination of absorbed dose to water in high energy photon beams.

Jan SeuntjensAnn Van Der PlaetsenKoenraad Van LaereHubert Thierens

1992

192IR brachytherapy sources : calibration of the NPL secondary standard radionuclide calibrator

MJ WoodsMJ RossiterJP SephtonTT WilliamsSEM LucasDFG ReherB DeneckeA AalbersHubert Thierens

A1 Journal Article in NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT

Acute myocardial infarction size and myoglobin release into serum.

Joris DelangheMarc De BuyzereLP CLUYSEHubert ThierensDenis Clement

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY

Calibration of low activity 192Ir brachytherapy sources in terms of reference air kerma rate with large volume spherical ionization chambers

Frans VerhaegenE van DijkHubert ThierensA AalbersJan Seuntjens

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Comparison of measured and calculated dose distributions in lung after electron beam treatment of the chest wall.

Ann Van Der PlaetsenJan SeuntjensM PIESSENSHubert Thierens

Effects of dose rate on the micronucleus yield in human lymphocytes exposed to X-rays

Anne VralHubert ThierensLeo De Ridder

Lymphocyte labeling with technetium-99M-HPPAO : a radiotoxicity study using the micronucleus assay

Hubert ThierensAnne VralJean P Van HaelstChristophe Van De WieleKarel HG SchelstraeteLeo De Ridder

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Role of the 5HT₂ receptor in the effects of serotonin and ketanserin on proliferation and differentiation of embryonic chick skin

Hilde BeeleHubert ThierensLeo De Ridder

A1 Journal Article in PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Skin organ culture model to test the toxicity of polyoxyethylene networks

Hilde BeeleHubert ThierensRobert DeveuxEric GoethalsLeo De Ridder

A1 Journal Article in BIOMATERIALS

Study of dose rate and split dose effects on the in vitro micronucleus yield in human lymphocytes exposed to X-rays

Anne VralHubert ThierensLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Study of dose-response and split-dose effects on the micronucleus (MN) yield in human lymphocytes exposed to different radiation qualities

Anne VralHubert ThierensLeo De Ridder

The healing of cranial defects by demineralised osseous implants: a radiographic, histological and radio-isotope study in rats

AC De BieLuc DermautHubert ThierensLeo De Ridder

Water calorimetry and ferrous sulphate dosimetry in high energy photon beams.

Jan SeuntjensAnn Van Der PlaetsenKoenraad Van LaereHubert Thierens

1991

Biological dosimetry using the micronucleus assay for lymphocytes : interindividual differences in dose response

Hubert ThierensAnne VralLeo De Ridder

A1 Journal Article in HEALTH PHYSICS

Evaluatie van stralingsschade door middel van de in vitro micronucleus test in perifere bloedlymfocyten

Anne VralHubert ThierensLeo De Ridder

A4 Journal Article in TIJDSCHRIFT VAN DE BELGISCHE VERENIGING VAN LABORATORIUM-TECHNOLOGEN = REVUE DE L'ASSOCIATION BELGE DES TECHNOLOGUES DE LABORATOIRE

Perturbation correction factors for some ionization chambres commonly applied in electron-beams

F WittkamperHubert ThierensAnn Van Der PlaetsenCarlos De WagterB Mijnheer

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

R59949, a diacylglycerolkinase inhibitor, stimulates collagen synthesis in embryonic chick skin and adult human skin in vitro

Hilde BeeleHubert ThierensLeo De Ridder

Radiation effects on the matrix synthesis of embryonic cartilage in vitro: a functional and electron microscopic investigation

Maria CornelissenHubert ThierensLeo De Ridder

The healing of cranial defects by demineralized osseous implants: a radiographical, histological and radio-isotope study in rats

A De BieLuc DermautHubert ThierensLeo De Ridder

A2 Journal Article in JOURNAL DE BIOLOGIE BUCCALE

1990

Effects of serotonin and ketanserin on the functional morphology of chick down feather bulbi in vitro

Hilde BeeleHubert ThierensBruno VerhasseltLeo De Ridder

A1 Journal Article in EXPERIENTIA

In vitro culture of chick down feather bulbi: a tool to obtain proliferating and differentiating keratinocytes in an organotypic structure

Hilde BeeleBruno VerhasseltHubert ThierensLeo De Ridder

A1 Journal Article in EXPERIENTIA

1989

The effects of ionizing radiation on the glycosaminoglycan synthesis in embryonic cartilage in vitro

Dirk De CraemerHubert ThierensMaria CornelissenHilde BeeleSabine LepercqueLeo De Ridder

A2 Journal Article in CYTOTECHNOLOGY

Calibration of low activity brachytherapy sources in terms of air kerma rate with a PTWLS-10 spherical ionizationchamber. Proc. Algemene Wetenschappelijke Vergadering van de Belgische Vereniging van Ziekenhuisfysici, Namur, 1991,9 p. (1991).

Hubert ThierensFrans VerhaegenJan Seuntjens

Dosimetry from organ to cellular dimensions. Computerized Medical Imaging and Graphics, 25, 2001, 187-194.

Hubert ThierensMA MONSIEURSB BRANST VAN DRIESSCHEI CHRISTIAENSRudi Dierckx

Perturbation correction factors for a NE2571 ionization chamber for 100 -280 kV X-rays Proceedings of the Second Biennal Meeting on Physics in Clinical Radiotherapy, may 28-30, Prague, Czech Republic, 1993, p. 11 (abstract).

Jan SeuntjensHubert ThierensU SCHNEIDER

Testing the temperature compensated BD-PND bubble detector Radiation Protection Dosimetry 65, 1996, pp. 425-428, 3 figg.

F VANHAVEREHubert ThierensM LOOS