Research Explorer

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Researcher

Helena Catharine Aegerter

Publications & Research Data

Awards & Distinctions

21 Results

2026

Chitin is a potent inducer of type 2 airway inflammation independent of endogenous chitinolytic activity

Jozefien DeclercqHelena Catharine AegerterUrsula SmoleKarel Van DammeEllen KetelaereInés LammensCaroline De WolfKarl VergoteManon VanheerswynghelsSofie De Prijck et al.

A1 Journal Article in ALLERGY

Effectiveness of biologics for reducing occlusive mucus plugs in patients with severe asthma : a systematic review

Helena Catharine AegerterChristopher E. BrightlingEleanor M. DunicanBart LambrechtNjira L. LugogoJohn D. NewellCeleste PorsbjergSarah SvenningsenDeborah ClarkeAndrew W. Lindsley et al.

A1 Journal Article in RESPIRATORY RESEARCH

Innate type 2 lymphocytes trigger an inflammatory switch in alveolar macrophages

Stijn VerwaerdeJean-François HastirSjoerd SchettersUrsula SmoleLeen SeysAntonio Pires da Silva BaptistaKieran EnglishMartijn SchuijsHelena Catharine AegerterKarel Van Damme et al.

A1 Journal Article in IMMUNITY

2025

A genetically encoded endogenous antibody recruitment strategy for innate immune-mediated killing of cancer cells

Justine AelvoetZifu ZhongClaudia Mariela Brenis GómezHelena Catharine AegerterBenoit LouageBart LambrechtBruno De GeestMartijn Schuijs

A1 Journal Article in ADVANCED MATERIALS

2024

Modulation is not an independent determinant of the viscoelastic properties of sputum in cystic fibrosis

Iris JanssensLeander JonckheereHelena Catharine AegerterM. De ConinckYannick Vande WeygaerdeBart LambrechtEva Van Braeckel

The epithelial era of asthma research : knowledge gaps and future direction for patient care

Christopher E. BrightlingGianni MaroneHelena Catharine AegerterPascal ChanezEnrico HefflerIan D. PavordKlaus F. RabeLena UllerDel Dorscheid[ missing ] on behalf of the Epithelial Science Expert Group

A1 Journal Article in EUROPEAN RESPIRATORY REVIEW

Ym1 protein crystals promote type 2 immunity

Ines HeyndrickxKim DeswarteKenneth VerstraeteKoen VerschuerenUrsula SmoleHelena Catharine AegerterAnn DansercoerHamida HammadSavvas SavvidesBart Lambrecht

A1 Journal Article in ELIFE

2023

Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice

Karel Van DammePieter HertensArne MartensElisabeth GilisDario PriemInge BruggemanAmelie FossoulJozefien DeclercqHelena Catharine AegerterAndy Wullaert et al.

A1 Journal Article in SCIENTIFIC REPORTS

The pathology of asthma : what is obstructing our view?

Helena Catharine AegerterBart Lambrecht

A1 Journal Article in ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE

The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function

Chrysante S. IliakisJustina KulikauskaiteHelena Catharine AegerterFengqi LiFederica PiattiniClaudia V. JakubzickMartin GuilliamsManfred KopfAndreas Wack

Editorial material

2022

Biology of lung macrophages in health and disease

Helena Catharine AegerterBart LambrechtClaudia V. Jakubzick

A1 Journal Article in IMMUNITY

Emerging paradigms in type 2 immunity

Hamida HammadNincy DebeufHelena Catharine AegerterAndrew BrownBart Lambrecht

A1 Journal Article in ANNUAL REVIEW OF IMMUNOLOGY

The Charcot-Leyden crystal protein Galectin-10 is not a major determinant of human regulatory T-cell function

Rebeca Arroyo-HorneroHelena Catharine AegerterIbrahim HamadBeatriz Corte-RealKatrien StaesBas van Der WoningKenneth VerstraeteSavvas SavvidesBart LambrechtMarkus Kleinewietfeld

A1 Journal Article in ALLERGY

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Levi HosteLisa RoelsLeslie NaesensVictor BosteelsStijn VanheeSam DupontCedric BosteelsRobin BrowaeysNiels VandammeKevin Verstaen et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

WS17.04 CFTR modulation alters the visco-elastic properties of airway mucus in cystic fibrosis patients

Iris JanssensHelena Catharine AegerterUrsula SmoleM. De ConinckYannick Vande WeygaerdeBart LambrechtEva Van Braeckel

2021

Charcot-Leyden crystals and other protein crystals driving type 2 immunity and allergy

Helena Catharine AegerterUrsula SmoleInes HeyndrickxKenneth VerstraeteSavvas SavvidesHamida HammadBart Lambrecht

A1 Journal Article in CURRENT OPINION IN IMMUNOLOGY

Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID) : a factorial, randomised, controlled trial

Jozefien DeclercqKarel Van DammeElisabeth De LeeuwBastiaan MaesCedric BosteelsSimon TavernierStefanie De BuyserRoos ColmanMaya HitesGil Verschelden et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Inhibition of miR-99a-5p prevents allergen-driven airway exacerbations without compromising type-2 memory responses in the intestine following helminth infection

Lewis EntwistleHelena Catharine AegerterStephanie CziesoEleni AmanitiRiccardo GuidiAbdul SesayNikolay NikolovProbir ChakravatyAlison HuynhJessica Mills et al.

A1 Journal Article in MUCOSAL IMMUNOLOGY

2020

Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis

Elien GevaertTim DelemarreJoyceline De VolderNan ZhangGabriële HoltappelsNatalie De RuyckEmma PerssonInes HeyndrickxKenneth VerstraeteHelena Catharine Aegerter et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection

Helena Catharine AegerterJustina KulikauskaiteStefania CrottaHarshil PatelGavin KellyEdith M. HesselMatthias MackSoren BeinkeAndreas Wack

A1 Journal Article in NATURE IMMUNOLOGY

2019

Protein crystallization promotes type 2 immunity and is reversible by antibody treatment

Emma PerssonKenneth VerstraeteInes HeyndrickxElien GevaertHelena Catharine AegerterJean-Michel PercierKim DeswarteKoen VerschuerenAnn DansercoerDelphine Gras et al.

A1 Journal Article in SCIENCE