Research Explorer

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Researcher

Heleen Van Acker

24 Results

2022

Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease

Charlotte RigautsLisa OstynEva VandeplasscheMozes SzeYves DondelingerLars VereeckeHeleen Van AckerAnne WillemsTom CoenyeAurélie Crabbé

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

2019

Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics

Aurélie CrabbéLisa OstynCharlotte RigautsMartijn RisseeuwMaarten DhaenensSimon DaledHeleen Van AckerDieter DeforceSerge Van CalenberghTom Coenye

A1 Journal Article in PLOS PATHOGENS

Laser-induced vapor nanobubbles improve diffusion in biofilms of antimicrobial agents for wound care

Eline TeirlinckJuan FraireHeleen Van AckerJasper WilleRosalie SwimbergheToon BransRanhua XiongMaarten MeireRoeland De MoorStefaan De SmedtTom CoenyeKevin Braeckmans

A2 Journal Article in BIOFILM

The role of small proteins in Burkholderia cenocepacia J2315 biofilm formation, persistence and intracellular growth

Heleen Van AckerAurélie CrabbéLisa OstynAndrea SassSimon DaledMaarten DhaenensDieter DeforceEline TeirlinckHerlinde De KeersmaeckerKevin BraeckmansTom Coenye

A2 Journal Article in BIOFILM

Various Evolutionary Trajectories Lead to Loss of the Tobramycin-Potentiating Activity of the Quorum-Sensing Inhibitor Baicalin Hydrate in Burkholderia cenocepacia Biofilms

Andrea SassLisa SlachmuyldersHeleen Van AckerIan VandenbusscheLisa OstynMona BovéAurélie CrabbéFilip Van NieuwerburghEmmanuel AbatihTom Coenye

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

2018

Coumarin reduces virulence and biofilm formation in Pseudomonas aeruginosa by affecting quorum sensing, type III secretion and C-di-GMP levels

Yunhui ZhangAndrea SassHeleen Van AckerJasper WilleBruno VerhasseltFilip Van NieuwerburghAurélie CrabbéTom Coenye

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Elucidation of the mechanism behind the potentiating activity of baicalin against Burkholderia cenocepacia biofilms

Lisa SlachmuyldersHeleen Van AckerGilles BrackmanAndrea SassFilip Van NieuwerburghTom Coenye

A1 Journal Article in PLOS ONE

Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms

Eline TeirlinckRanhua XiongToon BransKatrien ForierJuan FraireHeleen Van AckerNele MatthijsRiet De RyckeStefaan De SmedtTom CoenyeKevin Braeckmans

A1 Journal Article in NATURE COMMUNICATIONS

Targeting the nonmevalonate pathway in Burkholderia cenocepacia increases susceptibility to certain β-lactam antibiotics

Andrea SassAnnelien EveraertHeleen Van AckerFreija Van den DriesscheTom Coenye

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The mechanisms behind the potentiating activity of antibiotic adjuvants against Burkholderia cenocepacia biofilms

Lisa SlachmuyldersTom CoenyeHeleen Van Acker

2017

The role of reactive oxygen species in antibiotic-mediated killing of bacteria

Heleen Van AckerTom Coenye

A1 Journal Article in TRENDS IN MICROBIOLOGY

2016

The role of efflux and physiological adaptation in biofilm tolerance and resistance

Heleen Van AckerTom Coenye

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

The role of reactive oxygen species in antibiotic-induced cell death in Burkholderia cepacia complex bacteria

Heleen Van AckerTom Coenye

A1 Journal Article in PLOS ONE

2015

Genome-wide transcription start site profiling in biofilm-grown Burkholderia cenocepacia J2315

Andrea SassHeleen Van AckerFilip Van NieuwerburghDieter DeforceTom Coenye

A1 Journal Article in BMC GENOMICS

2014

Activity of disinfectants against multispecies biofilms formed by Staphylococcus aureus, Candida albicans and Pseudomonas aeruginosa

Sarah TavernierHeleen Van AckerHans NelisTom Coenye

A1 Journal Article in BIOFOULING

Differential roles of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells

Nele MatthijsHeleen Van AckerTom Coenye

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Involvement of toxin-antitoxin modules in Burkholderia cenocepacia biofilm persistence

Heleen Van AckerAndrea SassInne DhondtHans NelisTom Coenye

A1 Journal Article in PATHOGENS AND DISEASE

Molecular mechanisms of antimicrobial tolerance and resistance in bacterial and fungal biofilms

Heleen Van AckerTom Coenye

A1 Journal Article in TRENDS IN MICROBIOLOGY

Molecular mechanisms of persistence in Burkholderia cenocepacia biofilms

Heleen Van AckerTom CoenyeHans Nelis

The BCESM genomic region contains a regulator involved in quorum sensing and persistence in Burkholderia cenocepacia J2315

Heleen Van AckerEvelien De CanckFilip Van NieuwerburghAndrea SassDieter DeforceHans NelisTom Coenye

A1 Journal Article in FUTURE MICROBIOLOGY

2013

Biofilm-grown Burkholderia cepacia complex cells survive antibiotic treatment by avoiding production of reactive oxygen species

Heleen Van AckerAndrea SassKaren De RoyThomas MessiaenNico BoonHans NelisTom Coenye

A1 Journal Article in PLOS ONE

Phenotypic and genotypic characterisation of Burkholderia cenocepacia J2315 mutants affected in homoserine lactone and diffusible signal factor-based quorum sensing systems suggests interplay between both types of systems

Gilles BrackmanHeleen Van AckerTom Coenye

A1 Journal Article in PLOS ONE

2011

Molecular mechanisms of Chlorhexidine tolerance in Burkholderia cenocepacia biofilms

Tom CoenyeHeleen Van AckerElke Peeters

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

2010

In vitro activity of temocillin against planktonic and sessile Burkholderia cepacia complex bacteria

Heleen Van AckerHans NelisTom Coenye

A1 Journal Article in JOURNAL OF CYSTIC FIBROSIS