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Researcher
Heleen Van Acker
Profile
Projects
Publications
Activities
Awards & Distinctions
25
Results
2022
Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease
Charlotte Rigauts
Juliana Aizawa
Steven Taylor
Geraint B. Rogers
Matthias Govaerts
Paul Cos
Lisa Ostyn
Sarah Sims
Eva Vandeplassche
Mozes Sze
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2022
2020
Improving antibiotics' penetration and efficiency for treating biofilm infections by laser-induced vapor nanobubbles
Eline Teirlinck
Ranhua Xiong
Toon Brans
Katrien Forier
Juan Fraire
Heleen Van Acker
Stefaan De Smedt
Tom Coenye
Kevin Braeckmans
P1
Conference
2020
2019
Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics
Aurélie Crabbé
Lisa Ostyn
Sorien Staelens
Charlotte Rigauts
Martijn Risseeuw
Maarten Dhaenens
Simon Daled
Heleen Van Acker
Dieter Deforce
Serge Van Calenbergh
et al.
A1
Journal Article
in
PLOS PATHOGENS
2019
Laser-induced vapor nanobubbles improve diffusion in biofilms of antimicrobial agents for wound care
Eline Teirlinck
Juan Fraire
Heleen Van Acker
Jasper Wille
Rosalie Swimberghe
Toon Brans
Ranhua Xiong
Maarten Meire
Roeland De Moor
Stefaan De Smedt
et al.
A2
Journal Article
in
BIOFILM
2019
The role of small proteins in Burkholderia cenocepacia J2315 biofilm formation, persistence and intracellular growth
Heleen Van Acker
Aurélie Crabbé
Dukas Jurėnas
Lisa Ostyn
Andrea Sass
Simon Daled
Maarten Dhaenens
Dieter Deforce
Eline Teirlinck
Herlinde De Keersmaecker
et al.
A2
Journal Article
in
BIOFILM
2019
Various Evolutionary Trajectories Lead to Loss of the Tobramycin-Potentiating Activity of the Quorum-Sensing Inhibitor Baicalin Hydrate in Burkholderia cenocepacia Biofilms
Andrea Sass
Lisa Slachmuylders
Heleen Van Acker
Ian Vandenbussche
Lisa Ostyn
Mona Bové
Aurélie Crabbé
Laurent R Chiarelli
Silvia Buroni
Filip Van Nieuwerburgh
et al.
A1
Journal Article
in
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2019
2018
Coumarin reduces virulence and biofilm formation in Pseudomonas aeruginosa by affecting quorum sensing, type III secretion and C-di-GMP levels
Yunhui Zhang
Andrea Sass
Heleen Van Acker
Jasper Wille
Bruno Verhasselt
Filip Van Nieuwerburgh
Volkhard Kaever
Aurélie Crabbé
Tom Coenye
A1
Journal Article
in
FRONTIERS IN MICROBIOLOGY
2018
Elucidation of the mechanism behind the potentiating activity of baicalin against Burkholderia cenocepacia biofilms
Lisa Slachmuylders
Heleen Van Acker
Gilles Brackman
Andrea Sass
Filip Van Nieuwerburgh
Tom Coenye
A1
Journal Article
in
PLOS ONE
2018
Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms
Eline Teirlinck
Ranhua Xiong
Toon Brans
Katrien Forier
Juan Fraire
Heleen Van Acker
Nele Matthijs
Riet De Rycke
Stefaan De Smedt
Tom Coenye
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2018
Targeting the nonmevalonate pathway in Burkholderia cenocepacia increases susceptibility to certain β-lactam antibiotics
Andrea Sass
Annelien Everaert
Heleen Van Acker
Freija Van den Driessche
Tom Coenye
A1
Journal Article
in
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2018
The mechanisms behind the potentiating activity of antibiotic adjuvants against Burkholderia cenocepacia biofilms
Lisa Slachmuylders
Tom Coenye
Heleen Van Acker
Dissertation
2018
2017
The role of reactive oxygen species in antibiotic-mediated killing of bacteria
Heleen Van Acker
Tom Coenye
A1
Journal Article
in
TRENDS IN MICROBIOLOGY
2017
2016
The role of efflux and physiological adaptation in biofilm tolerance and resistance
Heleen Van Acker
Tom Coenye
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2016
The role of reactive oxygen species in antibiotic-induced cell death in Burkholderia cepacia complex bacteria
Heleen Van Acker
Jan Gielis
Marloes Acke
Freya Cools
Paul Cos
Tom Coenye
A1
Journal Article
in
PLOS ONE
2016
2015
Genome-wide transcription start site profiling in biofilm-grown Burkholderia cenocepacia J2315
Andrea Sass
Heleen Van Acker
Konrad Förstner
Filip Van Nieuwerburgh
Dieter Deforce
Jörg Vogel
Tom Coenye
A1
Journal Article
in
BMC GENOMICS
2015
2014
Activity of disinfectants against multispecies biofilms formed by Staphylococcus aureus, Candida albicans and Pseudomonas aeruginosa
Didem Kart
Sarah Tavernier
Heleen Van Acker
Hans Nelis
Tom Coenye
A1
Journal Article
in
BIOFOULING
2014
Differential roles of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells
Silvia Buroni
Nele Matthijs
Francesca Spadaro
Heleen Van Acker
Viola C Scoffone
Maria Rosalia Pasca
Giovanna Riccardi
Tom Coenye
A1
Journal Article
in
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2014
Involvement of toxin-antitoxin modules in Burkholderia cenocepacia biofilm persistence
Heleen Van Acker
Andrea Sass
Inne Dhondt
Hans Nelis
Tom Coenye
A1
Journal Article
in
PATHOGENS AND DISEASE
2014
Molecular mechanisms of antimicrobial tolerance and resistance in bacterial and fungal biofilms
Heleen Van Acker
Patrick Van Dijck
Tom Coenye
A1
Journal Article
in
TRENDS IN MICROBIOLOGY
2014
Molecular mechanisms of persistence in Burkholderia cenocepacia biofilms
Heleen Van Acker
Tom Coenye
Hans Nelis
Dissertation
2014
The BCESM genomic region contains a regulator involved in quorum sensing and persistence in Burkholderia cenocepacia J2315
Heleen Van Acker
Evelien De Canck
Filip Van Nieuwerburgh
Andrea Sass
Dieter Deforce
Hans Nelis
Tom Coenye
A1
Journal Article
in
FUTURE MICROBIOLOGY
2014
2013
Biofilm-grown Burkholderia cepacia complex cells survive antibiotic treatment by avoiding production of reactive oxygen species
Heleen Van Acker
Andrea Sass
Silvia Bazzini
Karen De Roy
Claudia Udine
Thomas Messiaen
Giovanna Riccardi
Nico Boon
Hans Nelis
Eshwar Mahenthiralingam
et al.
A1
Journal Article
in
PLOS ONE
2013
Phenotypic and genotypic characterisation of Burkholderia cenocepacia J2315 mutants affected in homoserine lactone and diffusible signal factor-based quorum sensing systems suggests interplay between both types of systems
Claudia Udine
Gilles Brackman
Silvia Bazzini
Silvia Buroni
Heleen Van Acker
Maria Rosalia Pasca
Giovanna Riccardi
Tom Coenye
A1
Journal Article
in
PLOS ONE
2013
2011
Molecular mechanisms of Chlorhexidine tolerance in Burkholderia cenocepacia biofilms
Tom Coenye
Heleen Van Acker
Elke Peeters
Andrea Sass
Silvia Buroni
Giovanna Riccardi
Eshwar Mahenthiralingam
A1
Journal Article
in
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2011
2010
In vitro activity of temocillin against planktonic and sessile Burkholderia cepacia complex bacteria
Heleen Van Acker
Elisabeth Van Snick
Hans Nelis
Tom Coenye
A1
Journal Article
in
JOURNAL OF CYSTIC FIBROSIS
2010