Research Explorer

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Researcher

Hege Michiels

Publications & Research Data

Awards & Distinctions

5 Results

2024

Adjusting for time-varying treatment switches in randomized clinical trials : the danger of extrapolation and how to address it

Hege MichielsAn VandeboschStijn Vansteelandt

A1 Journal Article in STATISTICS IN BIOPHARMACEUTICAL RESEARCH

2023

Causal estimands and estimation for randomized clinical trials with intercurrent events : addressing extrapolation

Hege MichielsStijn VansteelandtAn Vandebosch

Estimands and their estimators for clinical trials impacted by the COVID-19 pandemic : a report from the NISS Ingram Olkin Forum Series on unplanned clinical trial disruptions

Kelly Van LanckerSergey TarimaJonathan BartlettMadeline BauerBharani Bharani-DharanFrank BretzNancy FlournoyHege MichielsCamila Olarte ParraJames L. Rosenberger et al.

A1 Journal Article in STATISTICS IN BIOPHARMACEUTICAL RESEARCH

2022

Estimation and interpretation of vaccine efficacy in COVID-19 randomized clinical trials

Hege MichielsAn VandeboschStijn Vansteelandt

A2 Journal Article in STATISTICAL COMMUNICATIONS IN INFECTIOUS DISEASES

2021

A novel estimand to adjust for rescue treatment in randomized clinical trials

Hege MichielsCristina SottoAn VandeboschStijn Vansteelandt

A1 Journal Article in STATISTICS IN MEDICINE