Research Explorer

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Researcher

Hannelore Denys

Awards & Distinctions

148 Results

2024

A phase II, multicenter, open-label study of abemaciclib and letrozole in patients with estrogen receptor-positive rare ovarian cancer : ALEPRO trial

Tine OttenbourgsToon van GorpFrédéric KridelkaThaïs BaertHannelore DenysFrédéric SelleInge BaasAnne-Sophie Van RompuyDiether LambrechtsEls Van Nieuwenhuysen

A1 Journal Article in INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

A plain language summary of publication of the efficacy and safety of individualized niraparib dosing based on baseline body weight and platelet count in the PRIMA/ENGOT-OV26/GOG-3012 trial

Mansoor R MirzaAntonio González-MartínWhitney S GraybillDavid M O'MalleyLydia GabaOi Wah Stephanie YapEva M GuerraPeter G RoseJean-François BaurainSharad A Ghamande et al.

A1 Journal Article in FUTURE ONCOLOGY

Identification of potentially actionable genetic variants in epithelial ovarian cancer : a retrospective cohort study

Charlotte FieuwsJoni Van der MeulenKristiaan ProesmansEmiel De JaeghereSiebe LoontiensJo Van DorpePhilippe TummersHannelore DenysKoen Van de VijverKathleen Claes

A1 Journal Article in NPJ PRECISION ONCOLOGY

Overall survival and exploratory biomarker analyses of abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus chemotherapy in HR+, HER2+ metastatic breast cancer patients

Sara M. TolaneyShom GoelJorge NadalHannelore DenysManuel R. BorregoLacey M. LitchfieldJiangang LiuAdams K. AppiahYanyun ChenFabrice André

A1 Journal Article in CLINICAL CANCER RESEARCH

Performance of MRI for detection of ≥pT1b disease in local staging of endometrial cancer

Leonie Van VyncktPhilippe TummersHannelore DenysMenekse GökerSifrid HendrickxEline NaertRawand SalihiKoen Van de VijverGabriëlle Grada Hendrika van RamshorstDonatienne Van Weehaeghe et al.

A1 Journal Article in CANCERS

Sexual health in Belgian cervical cancer survivors : an exploratory qualitative study

Eline NaertHans Van HulleEmiel De JaeghereMarjolein OrijeSarah RoelsRawand SalihiKoen J. TraenKristien WattyLise-Marie KinnaerHans Verstraelen et al.

A1 Journal Article in QUALITY OF LIFE RESEARCH

VIMAP-trial : vulvar cancer intra-operative margin assessment using PET-CT

Anne-Sofie De CremPhilippe TummersRawand SalihiAmin MakarGlenn VergauwenKoen Van de VijverPieter De VisschereKathia De ManDonatienne Van WeehaegheKatrien Vandecasteele et al.

2023

A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment

Elly De VlieghereKoen Van de VijverEva BlondeelNathan CarpentierRouba GhobeiraJarne PauwelsSebastian RiemannManon MinsartCharlotte FieuwsJohanna Mestach et al.

A1 Journal Article in BIOMATERIALS RESEARCH

Atezolizumab combined with bevacizumab and platinum-based therapy for platinum-sensitive ovarian cancer : placebo-controlled randomized phase III ATALANTE/ENGOT-ov29 trial

Jean-Emmanuel KurtzEric Pujade-LauraineAna OakninLisa BelinKatharina LeitnerDavid CibulaHannelore DenysOra RosengartenManuel RodriguesNikolaus de Gregorio et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

BrainStorm : a multicenter international study to tackle CNS metastases in solid tumors

Diogo Martins-BrancoGuilherme Nader-MartaAndrea GombosPhilippe BarthelemyAnthony GoncalvesEdith BorcomanFlorian ClatotStephane HolbrechtsEleonora De Maio D’EspositoClaire Cheymol et al.

A1 Journal Article in NATURE MEDICINE

Clinical decision-making in older patients with cancer : a cross-sectional single-centre study to assess the impact of clinical judgement and patient preferences

Annelies DeldyckeHannelore DenysAlexander DecruyenaereAnja VelgheEline Naert

A1 Journal Article in ACTA CLINICA BELGICA

Completion surgery after intensity-modulated arc therapy for locally advanced cervical cancer : long-term follow-up and update on surgical outcome and oncologic results of a unique tertiary care single-center retrospective cohort

Axel Van DammeJulie RombautAmin MakarEmiel De JaeghereEline NaertHannelore DenysRawand SalihiPhilippe TummersKatrien Vandecasteele

A1 Journal Article in WORLD JOURNAL OF SURGICAL ONCOLOGY

Efficacy and safety of mirvetuximab soravtansine in patients with platinum-resistant ovarian cancer with high folate receptor alpha expression : results from the SORAYA study

UA MatulonisD LorussoA OakninS PignataA DeanHannelore DenysN ColomboT Van GorpJA KonnerMR Marin et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

Efficacy of olaparib in advanced cancers with germline or somatic mutations in BRCA1, BRCA2, CHEK2 and ATM, a Belgian Precision tumor-agnostic phase II study

S. JorisHannelore DenysJ. CollignonM. RasschaertD. T’Kint de RoodenbekeF.P. DuhouxJ.-L. CanonS. TejparJ. MebisL. Decoster et al.

A1 Journal Article in ESMO OPEN

Endometrial carcinosarcoma

G BoganiI Ray-CoquardN ConcinNYL NgoiP MoriceG CarusoT EnomotoK TakeharaHannelore DenysD Lorusso et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Histologic tumor type as a determinant of survival in hormone receptor-positive, HER2-negative, pT1-3 invasive ductal and lobular breast cancer

Menekse GOKERHannelore DenysAn HendrixOlivier De WeverKoen Van de VijverGeert Braems

A1 Journal Article in BREAST CANCER RESEARCH

Incidence, evolution and risk factors of hypophosphatemia in patients with solid tumors receiving ferric carboxymaltose : a retrospective cohort study

Alexander DecruyenaereKoen KortbeekSigurd DelangheSylvie RotteyHannelore DenysLore Lapeire

A1 Journal Article in ACTA CLINICA BELGICA

Integrating automated liquid handling in the separation workflow of extracellular vesicles enhances specificity and reproducibility

Sofie Van DorpeLien LippensRobin BoiyCláudio PinheiroGlenn VergauwenPekka RappuIlkka MiinalainenPhilippe TummersHannelore DenysOlivier De Wever et al.

A1 Journal Article in JOURNAL OF NANOBIOTECHNOLOGY

Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma : results of the phase II PRIMMO study

Emiel De JaeghereSandra TuyaertsAn M. T. Van NuffelAnn BelmansKris BogaertsRegina Baiden-AmissahLien LippensPeter VuylstekeStéphanie HenryXuan Bich Trinh et al.

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY

Performance of MRI for detection of >=T1b disease in local staging of endometrial cancer

Leonie Van VyncktPhilippe TummersEmiel De JaeghereHannelore DenysMenekse GOKERHendrickx SigiEline NaertRawand SalihiKoen Van de VijverGabriëlle Grada Hendrika van Ramshorst et al.

Prospective evaluation of the tolerability and efficacy of niraparib dosing based on baseline body weight and platelet count : results from the PRIMA/ENGOT-OV26/GOG-3012 trial

MR MirzaA González-MartínWS GraybillDM O'MalleyL GabaOW Stephanie YapEM GuerraPG RoseJF BaurainSA Ghamande et al.

A1 Journal Article in CANCER

Reply to Z.R. McCaw et al

Ursula A. MatulonisDomenica LorussoAna OakninSandro PignataAndrew DeanHannelore DenysNicoletta ColomboToon Van GorpJason A. KonnerMargarita Romeo Marin et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

Tisotumab vedotin in combination with carboplatin, pembrolizumab, or bevacizumab in recurrent or metastatic cervical cancer : results from the innovaTV 205/GOG-3024/ENGOT-cx8 study

Ignace VergoteEls Van NieuwenhuysenRoisin E. O'CearbhaillAnneke WestermannDomenica LorussoSharad GhamandeDearbhaile C. CollinsSusana BanerjeeCara A. MathewsChristine Gennigens et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

Tumor-infiltrating lymphocytes and PD-L1 expression in pleomorphic lobular breast carcinoma

Menekse GOKERStephanie DeblaereHannelore DenysGlenn VergauwenEline NaertLiv VeldemanChristel MontenRudy Van den BroeckeJo Van DorpeGeert Braems et al.

A1 Journal Article in CANCERS

Vaginal morbidity, sexual functioning, and health-related quality of life in cervical cancer survivors : a cross-sectional multicenter study (VAMOS)

Eline NaertAlexander DecruyenaereRenée BultijnckEmiel De JaeghereMarjolein OrijeRawand SalihiHans VerstraelenPhilippe TummersHannelore DenysKatrien Vandecasteele

A1 Journal Article in SUPPORTIVE CARE IN CANCER

2022

2022-RA-638-ESGO Pembrolizumab with multimodal immunomodulation in chemotherapy-pretreated cervical, endometrial, and uterine cancer : the PRIMMO phase II trial

Emiel De JaeghereSandra TuyaertsAnn M.T. van NuffelAnn BelmansKris BogaertsRegina Baiden-AmissahPeter VuylstekeStéphanie HenryXuan Bich TrinhPeter A. van Dam et al.

A case of corneal melting in a patient with HER2-positive breast cancer

Deborah PeetersMelissa VereeckenHannelore DenysDimitri Roels

A2 Journal Article in CASE REPORTS IN OPHTHALMOLOGY

A clearer view on ovarian clear cell carcinoma

Aglaja De PauwEline NaertKoen Van de VijverPhilippe TummersKatrien VandecasteeleHannelore Denys

A1 Journal Article in ACTA CLINICA BELGICA

Association of cell death markers with tumor immune cell infiltrates after chemo-radiation in cervical cancer

Teodora-Eugenia OlteanLien LippensKelly LemeireCaroline De TenderMarnik VuylstekeHannelore DenysKatrien VandecasteelePeter VandenabeeleSandy Adjemian Catani

A1 Journal Article in FRONTIERS IN ONCOLOGY

Biomarkers in gynecological cancer : the potential of tumor infiltrating immune cells and circulating extracellular vesicles

Lien LippensHannelore DenysAn HendrixKatrien Vandecasteele

Clear cell carcinoma of the endometrium

Giorgio BoganiIsabelle Ray-CoquardNicole ConcinNatalie Y.L. NgoiPhilippe MoriceTakayuki EnomotoKazuhiro TakeharaHannelore DenysDomenica LorussoRobert Coleman et al.

A1 Journal Article in GYNECOLOGIC ONCOLOGY

Completeness and selection bias of a Belgian multidisciplinary, registration-based study on the EFFectiveness and quality of Endometrial Cancer Treatment (EFFECT)

J VanbrabandN Van DammeG BoucheG SilversmitA De GeyndtE de JongeG JacomenF GoffinHannelore DenysF Amant

A1 Journal Article in BMC CANCER

Distinct transcriptional programs in ascitic and solid cancer cells induce different responses to chemotherapy in high-grade serous ovarian cancer

Nele LoretNiels VandammeJordy De ConinckJoachim TaminauKato De ClercqGillian BlanckeSven JonckheereSteven GoossensKelly LemeireSofie De Prijck et al.

A1 Journal Article in MOLECULAR CANCER RESEARCH

Efficacy and safety of olaparib according to age in BRCA1/2-mutated patients with recurrent platinum-sensitive ovarian cancer : analysis of the phase III SOLO2/ENGOT-Ov21 study

F. TrillschS. MahnerB. AtasevenR. AsherN. AryalC. DubotA. ClampR. PensonA. OzaA. Amit et al.

A1 Journal Article in GYNECOLOGIC ONCOLOGY

European experts consensus : BRCA/homologous recombination deficiency testing in first-line ovarian cancer

I. VergoteA. González-MartínI. Ray-CoquardP. HarterN. ColomboP. PujolD. LorussoM.R. MirzaB. BrasiunieneR. Madry et al.

A1 Journal Article in ANNALS OF ONCOLOGY

Genomic assays for lobular breast carcinoma

Menekse GOKERHannelore DenysKoen Van de VijverGeert Braems

A2 Journal Article in JOURNAL OF CLINICAL AND TRANSLATIONAL RESEARCH

Homologous recombination repair deficiency (HRD) testing in newly diagnosed advanced-stage epithelial ovarian cancer : a Belgian expert opinion

I VergoteHannelore DenysS. AltintasJ. KergerJ-F BaurainV BoursS. HenryKoen Van de VijverD. LambrechtsC. Gennigens

A2 Journal Article in FACTS VIEWS AND VISION IN OBGYN

Mental health and quality of life among patients with cancer during the SARS-CoV-2 pandemic : results from the longitudinal ONCOVID survey study

Emiel De JaeghereHeini KanervoRoos ColmanWim SchrauwenPaulien WestNele VandemaeleAglaja De PauwCeline JacobsIngeborg HildersonMicky Saerens et al.

A1 Journal Article in CANCERS

Multiple Bayesian network meta-analyses to establish therapeutic algorithms for metastatic triple negative breast cancer

F SchettiniS VenturiniM GiulianoM LambertiniDJ PinatoCE OnestiP De PlacidoN HarbeckD LüftnerHannelore Denys et al.

A1 Journal Article in CANCER TREATMENT REVIEWS

Prospective non-interventional BELOVA/BGOG-ov16 study on safety of frontline bevacizumab in elderly patients with FIGO stage IV ovarian cancer : a study of the Belgian and Luxembourg Gynaecological Oncology Group

Ignace VergoteEls Van NieuwenhuysenStefanie De WaeleChristof VulstekeCaroline LamotHeidi Van den BulckNele ClaesMarie-Pascale GraasGuy DebrockIsabelle Spoormans et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

ROSALINE : a phase II, neoadjuvant study targeting ROS1 in combination with endocrine therapy in invasive lobular carcinoma of the breast

E AgostinettoG Nader-MartaM PaesmansL AmeyeI VeysL BuisseretP NevenD TaylorC FontaineFP Duhoux et al.

A1 Journal Article in FUTURE ONCOLOGY

Safety of pre- or postoperative accelerated radiotherapy in 5 fractions : a randomized pilot trial

Vincent VakaetHans VanhulleKoen Van de VijverIngeborg HildersonEline NaertWilfried De NeveJo Van DorpeAn HendrixMenekse GOKERHerman Depypere et al.

A1 Journal Article in BREAST

2021

Accelerated radiotherapy in 5 fractions in breast cancer patients : physician-assessed toxicity and patient-related outcomes

Hans Van HulleLiv VeldemanHannelore DenysAn Hendrix

Adherence to and patient satisfaction with the combination therapy of exemestane and everolimus in postmenopausal women with HR+ HER2- advanced breast cancer : results from the IPSOC-mamma study

Veerle FoulonCarrie VisserSandra De CosterLise-Marie KinnaerEllen ReyndersAnne DeblanderPatrick BertelootKevin PunieHans WildiersVeronique Cocquyt et al.

Automated liquid handling for highly specific and reproducible density‐based separation of extracellular vesicles from human body fluids

Sofie Van DorpeLien LippensRobin BoiyHannelore DenysOlivier De WeverAn Hendrix

Debulking and HIPEC for ovarian cancer : effects of perfusion temperature on morbidity and cisplatin pharmacokinetics

Jesse DemuytereCharlotte CarlierWouter WillaertPhilippe TummersHannelore DenysOlivier Van KerschaverJoseph WeertsSarah CosynsWim Ceelen

Pembrolizumab, SBRT, and immunomodulation for recurrent and/or refractory cervical or endometrial carcinoma

Emiel De JaeghereSandra TuyaertsAnn M.T. Van NuffelLien LippensAn HendrixP. VuylstekeS. HenryX.B. TrinhP.A. Van DamS. Aspeslagh et al.

Reducing overall treatment time, a pilot RCT of neo-adjuvant radiotherapy in early breast cancer

Vincent VakaetHans Van HulleGeert BraemsKatrien VandecasteeleWilfried De NeveHannelore DenysLiv Veldeman

Risk of thrombo-embolic events in ovarian cancer : does bevacizumab tilt the scale? A systematic review and meta-analysis

Micky SaerensEmiel De JaeghereHeini KanervoNele VandemaeleHannelore DenysEline Naert

A1 Journal Article in CANCERS

Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions

Glenn VergauwenJoeri TulkensCláudio PinheiroFrancisco Avila CobosSandor DedeyneMarie-Angélique De ScheerderLinos VandekerckhoveFrancis ImpensIlkka MiinalainenGeert Braems et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Standard of care in 2021 for patients with ovarian cancer in Belgium

Ignace VergoteHannelore DenysJacques De GrèveChristine GennigensKoen Van de VijverJoseph KergerPeter VuylstekeJean-Francois Baurain

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Uterine serous carcinoma

Giorgio BoganiIsabelle Ray-CoquardNicole ConcinNatalie Y.L. NgoiPhilippe MoriceTakayuki EnomotoKazuhiro TakeharaHannelore DenysRemi A. NoutDomenica Lorusso et al.

A1 Journal Article in GYNECOLOGIC ONCOLOGY

2020

Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma

Elien De ThayeKoen Van de VijverJoni Van der MeulenJoachim TaminauGlenn WagemansHannelore DenysJo Van DorpeGeert BerxWim CeelenJan Van Bocxlaer et al.

A1 Journal Article in SCIENTIFIC REPORTS

Feasibility study on pre or postoperative accelerated radiotherapy (POP-ART) in breast cancer patients

Hans Van HulleVincent VakaetGiselle PostAnnick Van GrevelingChristel MontenAn HendrixKoen Van de VijverJo Van DorpePieter De VisschereGeert Braems et al.

A2 Journal Article in PILOT AND FEASIBILITY STUDIES

Heterogeneous response of chemotherapy-related cognitive decline in patients with breast cancer : a prospective study

Wim SchrauwenJoris Van de CaveyGuy VingerhoetsStijn VanheuleRudy Van den BroeckeHannelore Denys

A1 Journal Article in JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Immunologic impact of chemoradiation in cervical cancer and how immune cell infiltration could lead towards personalized treatment

Lien LippensMieke Van BockstalEmiel De JaegherePhilippe TummersAmin MakarSofie De GeyterKoen Van de VijverAn HendrixKatrien VandecasteeleHannelore Denys

A1 Journal Article in International Journal of Cancer

Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction

Joeri TulkensGlenn VergauwenJan Van DeunEdward GeeurickxBert DhondtLien LippensMarie-Angélique De ScheerderIlkka MiinalainenPekka RappuBruno De Geest et al.

A1 Journal Article in GUT

Isolation and engraftment of circulating tumor cells into zebrafish embryos to predict tumor response of ovarian cancer patients

Charlotte FieuwsJeroen VierstraeteKoen Van de VijverHannelore DenysKathleen Claes

PKPD modeling and dosing considerations in advanced ovarian cancer patients treated with cisplatin-based intraoperative intraperitoneal chemotherapy

Feifan XieJan Van BocxlaerPieter ColinCharlotte CarlierOlivier Van KerschaverJoseph WeertsHannelore DenysPhilippe TummersWouter WillaertWim Ceelen et al.

A1 Journal Article in AAPS JOURNAL

Safety and tolerability of subcutaneous trastuzumab at home administration, results of the phase IIIb open-label BELIS study in HER2-positive early breast cancer

Hannelore DenysCL Martinez-MenaMT MartensRG D'HondtML GraasE EvronG FriedNE Ben-BaruchC VulstekeMM Van Steenberghe

A1 Journal Article in BREAST CANCER RESEARCH AND TREATMENT

Splenic 18F-FDG uptake on baseline PET/CT is associated with oncological outcomes and tumor immune state in uterine cervical cancer

Emiel De JaeghereFrederiek LalooLien LippensMieke Van BockstalKathia De ManEline NaertJo Van DorpeKoen Van de VijverPhilippe TummersAmin Makar et al.

A1 Journal Article in GYNECOLOGIC ONCOLOGY

Splenic hematopoietic and stromal cells in cancer progression

Jonas SteenbruggeEmiel De JaeghereEvelyne MeyerHannelore DenysOlivier De Wever

A1 Journal Article in CANCER RESEARCH

Strong vaccine responses during chemotherapy are associated with prolonged cancer survival

Melief CJMWelters MJPI VergoteJR KroepGG KenterPB OttevangerTjalma WAAHannelore Denysvan Poelgeest MIEHW Nijman et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

The nocebo effect and tobacco control : first, do no harm?

Emiel De JaeghereGauthier BouchePiet HoebekePieter HolbrouckHannelore Denys

A1 Journal Article in MEDICAL HYPOTHESES

Treatment algorithm in patients with ovarian cancer

I. VergoteHannelore DenysJ. De GreveC. GennigensKoen Van de VijverJ. KergerP. VuylstekeJ. F. Baurain

A2 Journal Article in FACTS VIEWS AND VISION IN OBGYN

2019

Algorithms for molecular testing in solid tumours

A. HébrantM. LammensC. Van den BroeckeN. D’HaeneJ. Van den OordA. VandersticheleA. DendoovenP. NevenK. PunieG. Floris et al.

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Corneal features in trastuzumab emtansine treatment : not a rare occurrence

Els DeklerckHannelore DenysElke kreps

A1 Journal Article in BREAST CANCER RESEARCH AND TREATMENT

Fibroblasts fuel immune escape in the tumor microenvironment

Emiel De JaeghereHannelore DenysOlivier De Wever

A1 Journal Article in TRENDS IN CANCER

Immunologic impact of chemoradiation in cervical cancer and how immune cell infiltration could lead towards personalized treatment

Lien LippensMieke Van BockstalEmiel De JaegherePhilippe TummersAmin MakarSofie De GeyterKoen Van de VijverAn HendrixKatrien VandecasteeleHannelore Denys

Is locally advanced cervix adenocarcinoma less radiosensitive than squamous cell carcinoma?

Katrien VandecasteeleEmiel De JaegherePhilippe TummersAmin MakarPieter De VisschereKoen Van de VijverEline NaertHannelore Denys

Molecular test algorithms for breast tumours

A HébrantK PunieFP DuhouxC ColpaertG FlorisK LambeinP NevenM BerlièreR SalgadoM Chintinne et al.

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Morphological effects of chemoradiation therapy on cervical adenocarcinoma

Ann-Sophie CandaeleJo Van DorpeEmiel De JaegherePhilippe TummersAmin MakarPieter De VisschereHannelore DenysKatrien VandecasteeleKoen Van de Vijver

Niraparib in patients with newly diagnosed advanced ovarian cancer

A González-MartínB PothuriI VergoteR DePont ChristensenW GraybillMR MirzaC McCormickD LorussoP HoskinsG Freyer et al.

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

PRIMMO study protocol : a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer

Sandra TuyaertsAn MT Van NuffelEline NaertPeter A Van DamPeter VuylstekeAlex De CaluwéSandrine AspeslaghPiet DirixLien LippensEmiel De Jaeghere et al.

A1 Journal Article in BMC CANCER

Splenic metabolic activity as biomarker in cervical cancer

Emiel De JaeghereFrederiek LalooLien LippensKathia De ManMieke Van BockstalKoen Van de VijverPhilippe TummersAmin MakarPieter De VisschereOlivier De Wever et al.

The generation and use of recombinant extracellular vesicles as biological reference material

Edward GeeurickxJoeri TulkensBert DhondtJan Van DeunLien LippensGlenn VergauwenElisa HeyrmanDelphine De SutterKris GevaertFrancis Impens et al.

A1 Journal Article in NATURE COMMUNICATIONS

The role of epithelial-to-mesenchymal plasticity in ovarian cancer progression and therapy resistance

Nele LoretHannelore DenysPhilippe TummersGeert Berx

A1 Journal Article in CANCERS

Treatment of ovarian cancer with intraperitoneal platinum : heating up the debate

Emiel De JaeghereFélix GremonprezPhilippe TummersWouter WillaertWim CeelenFrédéric AmantHannelore Denys

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

2018

Corneal changes in trastuzumab emtansine treatment

Elke krepsTHIERRY DERVEAUXHannelore Denys

A1 Journal Article in CLINICAL BREAST CANCER

EXclusion of non-Involved uterus from the Target Volume (EXIT-trial) : an individualized treatment for locally advanced cervical cancer using modern radiotherapy and imaging techniques

Katrien VandecasteelePhilippe TummersMieke Van BockstalPieter De VisschereTom VercauterenWerner De GersemHannelore DenysEline NaertAmin MakarWilfried De Neve

A1 Journal Article in BMC CANCER

Neo-adjuvant treatment of adenocarcinoma and squamous cell carcinoma of the cervix results in significantly different pathological complete response rates

KAREN COUVREUREline NaertEmiel De JaegherePhilippe TummersAmin MakarPieter De VisschereMieke Van BockstalJo Van DorpeWilfried De NeveHannelore Denys et al.

A1 Journal Article in BMC CANCER

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxElisa HeyrmanJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensIlkka Miinalainen et al.

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxElisa HeyrmanJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensIlkka Miinalainen et al.

The small GTPase Rab27B stimulates secretion of a subpopulation of ARRDC1-positive small extracellular vesicles (SEV)

Lien LippensRobin BoiyBert DhondtBruno De GeestKatrien VandecasteeleHannelore DenysOlivier De WeverAn Hendrix

2017

A JAK3/STAT3 passenger activation in a lapatinib-acquired resistance model of HER2-amplified breast cancer

Mieke Van BockstalNadine Van RoyGlenn VergauwenKathleen LambeinVeronique CocquytLouis LibbrechtHannelore DenysMarc BrackeOlivier De Wever

Comparison of HER2 amplification status among breast cancer subgroups offers new insights in pathways of breast cancer progression

Kathleen LambeinMieke Van BockstalLIES VANDEMAELERudy Van den BroeckeVeronique CocquytSOFIE GEENENHannelore DenysLouis Libbrecht

A1 Journal Article in VIRCHOWS ARCHIV

Confounding factors in extracellular vesicle ultrafiltration and protein analysis

Glenn VergauwenBert DhondtJan Van DeunEvy TimmermanKris GevaertGeert BraemsRudy Van den BroeckeVeronique CocquytHannelore DenysOlivier De Wever et al.

Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research

Glenn VergauwenBert DhondtJan Van DeunEva De SmedtGeert BerxEvy TimmermanKris GevaertIlkka MiinalainenVeronique CocquytGeert Braems et al.

A1 Journal Article in SCIENTIFIC REPORTS

Extracellular vesicles to diagnose and treat cancer

Joeri TulkensLien LippensGlenn VergauwenSarah JeurissenBert DhondtHannelore DenysAn Hendrix

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Identification of confounding factors of EV isolation and protein analysis

Glenn VergauwenBert DhondtJan Van DeunEvy TimmermanKris GevaertVeronique CocquytGeert BraemsRudy Van den BroeckeHannelore DenysOlivier De Wever et al.

Incorporating PARP-inhibitors into clinical routine : a tailored treatment strategy to tackle ovarian cancer

Emiel De JaeghereKatrien VandecasteeleKathleen ClaesAmin MakarPhilippe TummersVeronique CocquytHannelore Denys

A1 Journal Article in ACTA CLINICA BELGICA

PRIMMO study : combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer

Sandra TuyaertsAn Van NuffelPeter Van DamPeter VuylstekeAlex De CaluwéPiet DirixKatrien VandecasteeleHannelore Denys

Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth

Lore LapeireAn HendrixEvelyne LecoutereMieke Van BockstalJo VandesompeleDawn MaynardGeert BraemsRudy Van den BroeckeCathérine MüllerMarc Bracke et al.

A1 Journal Article in ONCOTARGET

The isolation of morphologically intact and biologically active extracellular vesicles from the secretome of cancer-associated adipose tissue

Sarah JeurissenGlenn VergauwenJan Van DeunLore LapeireVictoria DepoorterIlkka MiinalainenRaija SormunenRudy Van den BroeckeGeert BraemsVeronique Cocquyt et al.

A1 Journal Article in CELL ADHESION & MIGRATION

2016

Advanced ovarian cancer: primary or interval debulking? : five categories of patients in view of the results of randomize trials and tumor biology : primary debulking surgery an interval debulking surgery for advanced ovarian cancer

Amin MakarClaes G TropéPhilippe TummersHannelore DenysKatrien Vandecasteele

A1 Journal Article in ONCOLOGIST

2015

Effect of Cx-mimetic peptide administration on breast cancer brain metastasis development: a preclinical serial MRI study

Valerie De MeulenaereElke DecrockSara NeytOlivier De WeverFilip De VosChristian VanhoveHannelore DenysBenedicte DescampsKarel Deblaere

Effect of GAP27 on breast cancer brain metastasis development: initial results

Valerie De MeulenaereElke DecrockSara NeytOlivier De WeverFilip De VosChristian VanhoveHannelore DenysBenedicte DescampsKarel Deblaere

Resection of single metachronous liver metastases from breast cancer stage I-II yield excellent overall and disease-free survival: single center experience and review of the literature

Céline VertriestGiammauro BerardiFederico TomassiniRudy Van den BroeckeHerman DepypereVeronique CocquytHannelore DenysSimon Van BelleRoberto Troisi

A1 Journal Article in DIGESTIVE SURGERY

Stromal protein expression in breast cancer is differentially regulated by TGF-β1

Mieke Van BockstalKathleen LambeinMireille Van GeleElly De VlieghereRidha LimameGeert BraemsMarc BrackeHannelore DenysLouis LibbrechtOlivier De Wever

When fat becomes an ally of the enemy : adipose tissue as collaborator in human breast cancer

Lore LapeireHannelore DenysVeronique CocquytOlivier De Wever

A2 Journal Article in HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION

2014

2013 Update of the American Society of Clinical Oncology/College of American Pathologists guideline for human epidermal growth factor receptor 2 testing: impact on immunohistochemistry-negative breast cancers

Kathleen LambeinMieke Van BockstalHannelore DenysLouis Libbrecht

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and JAK3/STAT3 signaling

Lore LapeireAn HendrixKathleen LambeinMieke Van BockstalGeert BraemsRudy Van den BroeckeRidha LimamePieter MestdaghJo VandesompeleChristian Vanhove et al.

Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and Jak/STAT3 signaling

Lore LapeireAn HendrixKathleen LambeinMieke Van BockstalGeert BraemsRudy Van den BroeckeRIDHA LIMAMEPieter MestdaghJo VandesompeleChristian Vanhove et al.

A1 Journal Article in CANCER RESEARCH

Colloidal stability of nano-sized particles in the peritoneal fluid : towards optimizing drug delivery systems for intraperitoneal therapy

George DakwarElisa ZagatoJoris DelangheSabina HobelAchim AignerHannelore DenysKevin BraeckmansWim CeelenStefaan De SmedtKatrien Remaut

A1 Journal Article in ACTA BIOMATERIALIA

Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion

Mieke Van BockstalKathleen LambeinMireille Van GeleElly De VlieghereRIDHA LIMAMEGeert BraemsRudy Van den BroeckeVeronique CocquytHannelore DenysMarc Bracke et al.

A2 Journal Article in ONCOSCIENCE

HER2 status in breast cancer : an in-depth pathobiological analysis

Kathleen LambeinLouis LibbrechtHannelore Denys

Histopathological characterization of ductal carcinoma in situ (DCIS) of the breast according to HER2 amplification status and molecular subtype

Mieke Van BockstalKathleen LambeinHannelore DenysGeert BraemsANN NUYTSRudy Van den BroeckeVeronique CocquytOlivier De WeverLouis Libbrecht

A1 Journal Article in VIRCHOWS ARCHIV

Stromal characteristics are potential prognostic markers for ipsilateral locoregional recurrence in ductal carcinoma in situ (DCIS)

Mieke Van BockstalKathleen LambeinOlivier De WeverMarleen PraetVeronique CocquytRudy Van den BroeckeGeert BraemsHannelore DenysLouis Libbrecht

2013

Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling

Astrid De BoeckPatrick PauwelsKaren HensenJean-Luc RummensWendy WestbroekAn HendrixDawn MaynardHannelore DenysKathleen LambeinGeert Braems et al.

A1 Journal Article in GUT

Completion surgery after intensity-modulated arc therapy in the treatment of locally advanced cervical cancer feasibility, surgical outcome, and oncologic results

Philippe TummersAmin MakarKatrien VandecasteeleGert De MeerleerHannelore DenysPieter De VisschereLouke DelrueGeert VilleirsKathleen LambeinRudy Van den Broecke

A1 Journal Article in INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Distinguishing score 0 from score 1+ in HER2 immunohistochemistry-negative breast cancer: clinical and pathobiological relevance

Kathleen LambeinMieke Van BockstalLIES VANDEMAELESOFIE GEENENIsabelle RottiersANN NUYTSBART MATTHYSMarleen PraetHannelore DenysLouis Libbrecht

A1 Journal Article in AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Evaluation of the quality of the management of cancer of the corpus uteri: selection of relevant quality indicators and implementation in Belgium

J WerbrouckG BoucheE de JongeG JacomenV D'HondtHannelore DenysE Van LimbergenB VandermeerschH De SchutterE Van Eycken et al.

A1 Journal Article in GYNECOLOGIC ONCOLOGY

Multicenter cross-sectional study comparing quality of life, body image after breast cancer surgery

Daan De MaeseneerMICHIEL STRIJBOSPhillip BlondeelRudy Van den BroeckeHerman DepypereGeert BraemsHannelore DenysSimon Van BelleVeronique Cocquyt

Stromal architecture and periductal decorin are potential prognostic markers for ipsilateral locoregional recurrence in ductal carcinoma in situ of the breast

Mieke Van BockstalKathleen LambeinOlivier GevaertOlivier De WeverMarleen PraetVeronique CocquytRudy Van den BroeckeGeert BraemsHannelore DenysLouis Libbrecht

A1 Journal Article in HISTOPATHOLOGY

The addition of bevacizumab to standard chemotherapy in breast cancer : which patient benefits the most?

VIBEKE KRUSEHannelore DenysRudy Van den BroeckeSimon Van BelleVeronique Cocquyt

A1 Journal Article in SPRINGERPLUS

Vacuolar H+ ATPase expression and activity is required for Rab27B dependent invasive growth and metastasis of breast cancer

An HendrixRaija SormunenWendy WestbroekKathleen LambeinHannelore DenysGwen SysGeert BraemsRudy Van den BroeckeVeronique CocquytChristian Gespach et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

2012

Cytoreduction and hyperthermic intraperitoneal chemoperfusion in women with heavily pretreated recurrent ovarian cancer

Wim CeelenYves Van NieuwenhoveSimon Van BelleHannelore DenysPiet Pattyn

A1 Journal Article in ANNALS OF SURGICAL ONCOLOGY

Intensity-modulated arc therapy with cisplatin as neo-adjuvant treatment for primary irresectable cervical cancer : toxicity, tumour response and outcome

Katrien VandecasteeleAmin MakarRudy Van den BroeckeLouke DelrueHannelore DenysKathleen LambeinBieke LambertMarc Van EijkerenPhilippe TummersGert De Meerleer

A1 Journal Article in STRAHLENTHERAPIE UND ONKOLOGIE

Postoperative intensity-modulated arc therapy for cervical and endometrial cancer : a prospective report on toxicity

Katrien VandecasteelePhilippe TummersAmin MakarMarc Van EijkerenLouke DelrueHannelore DenysBieke LambertANNE-SOPHIE BEERENSRudy Van den BroeckeKathleen Lambein et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Surgery after intensity modulated arc therapy in the treatment of locally advanced cervical cancer : feasibility and surgical outcome

Philippe TummersAmin MakarKatrien VandecasteeleGert De MeerleerHannelore DenysPieter De VisschereGeert VilleirsKathleen LambeinRudy Van den Broecke

Value of magnetic resonance and 18FDG PET-CT in predicting tumor response and resectability of primary locally advanced cervical cancer after treatment with intensity-modulated arc therapy : a prospective pathology-matched study

Katrien VandecasteeleLouke DelrueBieke LambertAmin MakarKathleen LambeinHannelore DenysPhilippe TummersRudy Van den BroeckeGeert VilleirsGert De Meerleer

A1 Journal Article in INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Whole abdominopelvic radiotherapy (WAPRT) using intensity modulated arc therapy (IMAT) as palliation for chemotherapy-resistant ovarian cancer

Katrien VandecasteeleAmin MakarPhilippe TummersHannelore DenysRudy Van den BroeckeLouke DelruePieter De VisscherePiet OstGert De Meerleer

2011

Adipose tissue in breast cancer : not an idle bystander but an active participant in breast cancer progression

Lore LapeireAn HendrixKathleen LambeinGeert BraemsP ValetRudy Van den BroeckeMarc BrackeVeronique CocquytHannelore DenysOlivier De Wever

PARP inhibitors in oncology: a new synthetic lethal approach to cancer therapy

VIBEKE KRUSESylvie RotteyOle De BackerSimon Van BelleVeronique CocquytHannelore Denys

A1 Journal Article in ACTA CLINICA BELGICA

PARP-inhibitors in breast and ovarian cancer

VIBEKE KRUSEVeronique CocquytRudy Van den BroeckeGeert BraemsHannelore Denys

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Relationship between pathological features, HER2 protein expression and HER2 and CEP17 copy number in breast cancer: biological and methodological considerations

Kathleen LambeinMarleen PraetRamses ForsythRudy Van den BroeckeGeert BraemsBART MATTHYSVeronique CocquytHannelore DenysPatrick PauwelsLouis Libbrecht

A1 Journal Article in JOURNAL OF CLINICAL PATHOLOGY

Use of tamoxifen before and during pregnancy

Geert BraemsHannelore DenysOlivier De WeverVeronique CocquytRudy Van den Broecke

A1 Journal Article in ONCOLOGIST

Whole abdominopelvic radiotherapy using intensity-modulated arc therapy in the palliative treatment of chemotherapy-resistant ovarian cancer with bulky peritoneal disease: a single-institution experience

Gert De MeerleerKatrien VandecasteelePiet OstLouke DelrueHannelore DenysAmin MakarBruno SpeleersSimon Van BelleRudy Van den BroeckeValérie Fonteyne et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

2010

2010 Impakt breast cancer conference

Hannelore DenysGeert Braems

Cardiac toxicity of trastuzumab : experience at the Ghent University Hospital, Belgium

CAROLINE LAMOTSylvie RotteyTine De BackerLucas Van BortelHugo RobaysSimon Van BelleHannelore DenysVeronique Cocquyt

A1 Journal Article in ACTA CLINICA BELGICA

Cytoreduction and hyperthermic intraperitoneal chemoperfusion in women with heavily pretreated recurrent ovarian cancer

Wim CeelenYves Van NieuwenhoveSimon Van BelleHannelore DenysPiet Pattyn

Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis

An HendrixDawn MaynardPatrick PauwelsGeert BraemsHannelore DenysRudy Van den BroeckeJo LambertSimon Van BelleVeronique CocquytChristian Gespach et al.

A1 Journal Article in JOURNAL OF THE NATIONAL CANCER INSTITUTE

The secretory GTPase RAB27b drives poor prognosis in ER alpha-positive breast cancer

An HendrixHannelore DenysGeert BraemsPatrick PauwelsRudy Van den BroeckeVeronique CocquytWendy WestbroekMarc BrackeOlivier De Wever

2009

Assessment of the resectability after chemoradiation of primary irresectable cervical cancer by MRI

Louke DelrueKatrien VandecasteeleBieke LambertAmin MakarKathleen LambeinGeert VilleirsPhilippe DuyckPhilippe TummersHannelore DenysGert De Meerleer

Biomarkers ER, PR, HER-2 En topoisomerase II alpha in correlation with response to neoadjuvant chemotherapy for primary breast cancer

Kathleen LambeinPatrick PauwelsMICHIEL BUIJSROGGEHannelore DenysRudy Van den BroeckeHerman DepypereSimon Van BelleE DochyVeronique Cocquyt

Development and validation of a liquid chromatographic method for the simultaneous determination of four anthracyclines and their respective 13-S-dihydro metabolites in plasma and saliva

Kristof MaudensChristophe StoveVeronique CocquytHannelore DenysWilly Lambert

A1 Journal Article in Journal of Chromatography B

Magnetic resonance imaging to assess the resectability after chemoradiation of primary irresectable cervical cancer

Louke DelrueKatrien VandecasteeleBieke LambertAmin MakarKathleen LambeinGeert VilleirsPhilippe TummersWilfried De NeveHannelore DenysGert De Meerleer

The extracellular matrix regulates cancer progression and therapy response: implications for prognosis and treatment

Hannelore DenysGeert BraemsKathleen LambeinPatrick PauwelsAn HendrixAstrid De BoeckVeronique MathieuMarc BrackeOlivier De Wever

A1 Journal Article in CURRENT PHARMACEUTICAL DESIGN

The secretory small GTPase Rab27B regulates invasive tumor growth and metastasis through extracellular heat shock protein 90 alpha

An HendrixD MaynardP PauwelsG BraemsHannelore DenysRudy Van den BroeckeSimon Van BelleVeronique CocquytMarc BrackeM Seabra et al.

Trastuzumab: de eerste monoklonale antistof als therapie in de strijd tegen borstkanker

Liesbeth DamenHannelore DenysVeronique CocquytRudy Van den Broecke

A2 Journal Article in Tijdschrift voor Geneeskunde

2008

A pilot study to investigate the feasibility and cardiac effects of pegylated liposomal doxorubicin (PL-DOX) as adjuvant therapy in medically fit elderly breast cancer patients

Hans WildiersRuxandra JurcutJavier GanameLieven HerbotsPatrick NevenJulie De BackerHannelore DenysVeronique CocquytFrank RademakersJens-Uwe Voigt et al.

A1 Journal Article in CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Differential impact of TGF-β and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion

Hannelore DenysLara DeryckeAn HendrixWendy WestbroekAlexander GheldofKishan NarinePatrick PauwelsChristian GespachMarc BrackeOlivier De Wever

A1 Journal Article in CANCER LETTERS

OSTEOSARCOMA WITH EXTENSIVE CALCIFIED PLEURAL METASTASES AT DIAGNOSIS

NATACHA VERBEKEKoenraad VerstraeteGwen SysRamses ForsythD. KluyskensHannelore DenysDirk UyttendaeleSylvie Rottey

A1 Journal Article in Acta Clinica Belgica

Pathological response in radical hysterectomy following intensity modulated arc therapy (IMAT) in the multimodality treatment of locally advanced cervical carcinoma

Kathleen LambeinKatrien VandecasteeleAmin MakarGeert VilleirsHannelore DenysVeronique CocquytRudy Van den BroeckeValérie FonteyneLouke DelruePhilippe Tummers et al.

Preceding Sentinel Node Biopsy in Early Breast Cancer: Does it Affect the Number of Axillary Lymph Nodes?

Geert BraemsHannelore DenysVeronique CocquytRudy Van den Broecke

A1 Journal Article in ACTA CHIRURGICA BELGICA

Radical hysterectomy following Intensity Modulated Arc Therapy (IMAT) in the multimodality treatment of locally advanced cervical cancer

Amin MakarKatrien VandecasteeleGeert VilleirsHannelore DenysRudy Van den BroeckeVeronique CocquytKathleen LambeinValérie FonteyneLouke DelruePhilippe Tummers et al.

Strain Rate Imaging Detects Early Cardiac Effects of Pegylated Liposomal Doxorubicin as Adjuvant Therapy in Elderly Patients with Breast Cancer

Ruxandra JurcutHans WildiersJavier GanameJan D'hoogeJulie De BackerHannelore DenysRobert ParidaensFrank RademakersJens-Uwe Voigt

A1 Journal Article in JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY

Toxicity, tumour response, and resectability after IMAT +/- cisplatin for primary irresectable carcinoma of the cervix

Katrien VandecasteeleAmin MakarGeert VilleirsHannelore DenysWilfried De NeveValérie FonteyneRudy Van den BroeckeVeronique CocquytKathleen LambeinCarlos De Wagter et al.