Research Explorer

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Researcher

Hanne Huysmans

Awards & Distinctions

10 Results

2023

Investigating the impact of orientation of a subcutaneous sensor to its foreign body reaction and fibrotic capsule thickness in pigs using histological analysis

Jeroen CarlierLobke De BelsAsins AznarHanne HuysmansLieven VlaminckWard De SpiegelaereCharlotte Cuypers

The pig as surrogate model for humans for the rational design of an invisible sensor for subcutaneous continuous glucose detection for type 1 diabetes management

Jeroen CarlierMathias DevreeseE Asins AznarHanne HuysmansLieven VlaminckDanaë DelbekeKatrien VanderperrenWard De Spiegelaere

2021

Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs

Zifu ZhongSéan Mc CaffertyLisa OpsomerHaixiu WangHanne HuysmansJoyca De TemmermanStefan LienenklausJoão Portela CataniFrancis CombesNiek Sanders

A1 Journal Article in MOLECULAR THERAPY

2019

Expression kinetics and innate immune response after electroporation and LNP-mediated delivery of a self-amplifying mRNA in the skin

Hanne HuysmansZifu ZhongJoyca De TemmermanBarbara L MuiYing K TamSéan Mc CaffertyArlieke GitselsDaisy VanrompayNiek Sanders

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

Improving the repeatability and efficacy of intradermal electroporated self-replicating mRNA

Hanne HuysmansJoyca De TemmermanZifu ZhongSéan Mc CaffertyFrancis CombesFreddy HaesebrouckNiek Sanders

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

Intradermal delivery strategies of mRNA-based therapeutics in mice and pigs

Hanne HuysmansNiek Sanders

Mononuclear but not polymorphonuclear phagocyte depletion increases circulation times and improves mammary tumor-homing efficiency of donor bone marrow-derived monocytes

Francis CombesAlexandros Marios SofiasSéan Mc CaffertyHanne HuysmansJoyca De TemmermanSjoerd HakEvelyne MeyerNiek Sanders

A1 Journal Article in CANCERS

2018

Comparison of the expression kinetics and immunostimulatory activity of replicating mRNA, nonreplicating mRNA, and pDNA after intradermal electroporation in pigs

Bregje LeymanHanne HuysmansSéan Mc CaffertyFrancis CombesEric CoxBert DevriendtNiek Sanders

A1 Journal Article in MOLECULAR PHARMACEUTICS

mRNA therapeutics deliver a hopeful message

Zifu ZhongSéan Mc CaffertyFrancis CombesHanne HuysmansJoyca De TemmermanArlieke GitselsDaisy VanrompayJoão Portela CataniNiek Sanders

A1 Journal Article in NANO TODAY

2017

Evaluation of a xenogeneic vascular endothelial growth factor-2 vaccine in two preclinical metastatic tumor models in mice

Sofie DeniesBregje LeymanHanne HuysmansFrancis CombesSéan Mc CaffertyLaetitia CiccheleroMarjan SteppeJoyca De TemmermanNiek Sanders

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY