Research Explorer

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Researcher

Gwenn Waerlop

Publications & Research Data

Awards & Distinctions

13 Results

2025

A novel carbohydrate fatty-acid monosulphate ester, squalane-in-water adjuvant is safe and enhances inactivated influenza vaccine immunogenicity in older adults

Valentino D'OnofrioBart JacobsAzhar AlhatemiSimon De GussemMarjolein VerstraeteSharon PorrezAnthony WillemsFien De BoeverGwenn WaerlopGeert Leroux-Roels et al.

A1 Journal Article in VACCINES

AS04 drives superior cross-protective antibody response by increased NOTCH signaling of dendritic cells and proliferation of memory B cells

Valentino D'OnofrioAna Carolina SantanaMarthe PauwelsGwenn WaerlopAnthony WillemsFien De BoeverMartin MüllerPeter SehrTim WaterboerIsabel Leroux-Roels et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2024

Evaluation of safety, immunogenicity and cross-reactive immunity of OVX836, a nucleoprotein-based universal influenza vaccine, in older adults

Bart JacobsIsabel Leroux-RoelsJacques BruhwylerNicola GrothGwenn WaerlopYorick JanssensJessika TourneurFien De BoeverAzhar AlhatemiPhilippe Moris et al.

A1 Journal Article in VACCINES

Safety and immunogenicity of a carbohydrate fatty acid monosulphate ester adjuvant combined with a low-dose quadrivalent split-virion inactivated influenza vaccine : a randomised, observer-blind, active-controlled, first-in-human, phase 1 study

Valentino D'OnofrioSharon PorrezBart JacobsAzhar AlhatemiFien De BoeverGwenn WaerlopEls MichelsFrancesca VanniAlessandro ManentiGeert Leroux-Roels et al.

A1 Journal Article in VACCINES

Safety and immunogenicity of the live-attenuated hRVFV-4s vaccine against Rift Valley fever in healthy adults : a dose-escalation, placebo-controlled, first-in-human, phase 1 randomised clinical trial

Isabel Leroux-RoelsChittappen Kandiyil PrajeethAmare AregayNiranjana NairGuus F RimmelzwaanAlbert D M E OsterhausSimone KardinahlSabrina PelzStephan BauerValentino D'Onofrio et al.

A1 Journal Article in LANCET INFECTIOUS DISEASES

2023

Harmonization of cellular immunoassays for the evaluation of influenza vaccine immunogenicity

Gwenn WaerlopIsabel Leroux-RoelsGeert Leroux-Roels

Immune responses in healthy adults elicited by a bivalent norovirus vaccine candidate composed of GI.4 and GII.4 VLPs without adjuvant

Gwenn WaerlopYorick JanssensBart JacobsFranziska JarczowskiAndré DiessnerGeert Leroux-RoelsVictor KlimyukIsabel Leroux-RoelsFrank Thieme

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Immunogenicity, safety, and preliminary efficacy evaluation of OVX836, a nucleoprotein-based universal influenza A vaccine candidate : a randomised, double-blind, placebo-controlled, phase 2a trial

Isabel Leroux-RoelsPaul WillemsGwenn WaerlopYorick JanssensJessika TourneurFien De BoeverJacques BruhwylerAzhar AlhatemiBart JacobsFlorence Nicolas et al.

A1 Journal Article in LANCET INFECTIOUS DISEASES

2022

A randomized, double-blind, placebo-controlled, dose-escalating phase I trial to evaluate safety and immunogenicity of a plant-produced, bivalent, recombinant norovirus-like particle vaccine

Isabel Leroux-RoelsCathy MaesJasper JoyeBart JacobsFranziska JarczowskiAndré DiessnerYorick JanssensGwenn WaerlopKirsi TamminenSuvi Heinimäki et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Harmonization and qualification of an IFN-γ Enzyme-Linked ImmunoSpot assay (ELISPOT) to measure influenza-specific cell-mediated immunity within the FLUCOP consortium

Gwenn WaerlopGeert Leroux-RoelsTeresa LambeDuncan BellamyDonata MedagliniElena PettiniRebecca Jane CoxMai-Chi TrieuRichard DaviesGeir Bredholt et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Harmonization and qualification of intracellular cytokine staining to measure influenza-specific CD4+ T cell immunity within the FLUCOP consortium

Sarah BegueGwenn WaerlopBruno SalaunMichel JanssensDuncan BellamyRebecca Jane CoxRichard DaviesElena GianchecchiDonata MedagliniEmanuele Montomoli et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Randomized, double-blind, reference-controlled, phase 2a study evaluating the immunogenicity and safety of OVX836, a nucleoprotein-based influenza vaccine

Isabel Leroux-RoelsGwenn WaerlopJessika TourneurFien De BoeverCatherine MaesJacques BruhwylerDelphine Guyon-GellinPhilippe MorisJudith Del CampoPaul Willems et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

The role of cell-mediated immunity against influenza and its implications for vaccine evaluation

Yorick JanssensJasper JoyeGwenn WaerlopFrédéric ClementGeert Leroux-RoelsIsabel Leroux-Roels

A1 Journal Article in FRONTIERS IN IMMUNOLOGY