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Researcher
Guy Brusselle
Profile
Projects
Publications
Activities
Awards & Distinctions
566
Results
2025
Anti-IL-5 treatment, but not neutrophil interference, attenuates inflammation in a mixed granulocytic asthma mouse model, elicited by air pollution
Joyceline De Volder
Annelies Bontinck
Valerie Haelterman
Louis Boon
Guy Joos
Guy Brusselle
Tania Maes
A1
Journal Article
in
RESPIRATORY RESEARCH
2025
Augmenting clinical trials in asthma through digital technology, decentralised designs, and person-centric endpoints : opportunities and challenges
Job F M van Boven
Richard W Costello
Kit C B Roes
Guy Brusselle
Kjeld Hansen
Jerry A Krishnan
Christopher E Brightling
Nicolas Roche
Salman Siddiqui
Bruce J Kirenga
et al.
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2025
Biologics and airway remodeling in asthma : early, late, and potential preventive effects
G. Varricchi
R. Poto
M. Lommatzsch
Guy Brusselle
F. Braido
J. C. Virchow
G. W. Canonica
A1
Journal Article
in
ALLERGY
2025
Dupilumab induces long-term on-treatment clinical remission in patients with type 2 asthma
Ian D. Pavord
Klaus F. Rabe
Elliot Israel
Stanley J. Szefler
Guy Brusselle
Nami Pandit-Abid
Arman Altincatal
Zhen Chen
Nikhil Amin
Asif H. Khan
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2025
Impact of respiratory and cardiovascular drug exposure on lung function trajectories
Xander Bertels
Delphine Vauterin
Sebastian Riemann
Frauke Van Vaerenbergh
Kristiaan Proesmans
André G. Uitterlinden
M. Arfan Ikram
Guy Brusselle
Bruno H. Stricker
Lies Lahousse
A1
Journal Article
in
ANNALS OF THE AMERICAN THORACIC SOCIETY
2025
Preserved ratio impaired spirometry (PRISm) : prognostic, preventable and treatable?
Guy Brusselle
Sebastian Riemann
Editorial material
2025
Prospective REALITI-A study : 2-year real-world benefits of mepolizumab in severe asthma
Cristiano Caruso
G. Walter Canonica
Manish Patel
Andrew Smith
Mark C. Liu
Rafael Alfonso-Cristancho
Robert G. Price
Rupert W. Jakes
Lydia Demetriou
Antonio Valero
et al.
A2
Journal Article
in
CHEST PULMONARY
2025
Relapse of Eosinophilic Granulomatosis With Polyangiitis (EGPA) Despite Maintenance Treatment With Low-Dose Mepolizumab
Aurelie Vanthuyne
Sebastian Riemann
Guy Brusselle
U
Journal Article
in
Respirology Case Reports
2025
Roads to remission : evolving treatment concepts in type 2 inflammatory diseases
Marek Lommatzsch
Katharina Blumchen
Lisa A. Beck
Jean Bousquet
Guy Brusselle
Wytske J. Fokkens
Eckard Hamelmann
Susanne Lau
Hagen Ott
Oliver Pfaar
et al.
A1
Journal Article
in
ECLINICALMEDICINE
2025
Unraveling inflammatory responses in pollutant-aggravated allergic asthma
Joyceline De Volder
Tania Maes
Guy Brusselle
Dissertation
2025
2024
Aanbevelingen voor de behandeling van astma bij volwassenen in de eerstelijnsgezondheidszorg
Sebastian Riemann
Guy Brusselle
A4
Journal Article
in
MEDI-SFEER
2024
All-cause mortality of Staging of Airflow Obstruction by Ratio-categorized patients with Chronic Obstructive Pulmonary Disease among the general population
Xander Bertels
Sebastian Riemann
Delphine Vauterin
Lies Lahousse
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2024
Anti-inflammatoire reliever (AIR) als eerstekeuzebehandeling bij mild astma : nieuwe aanbevelingen op basis van de 2023 ERS Task Force ICS/formoterol in mild astma
Sebastian Riemann
Guy Brusselle
A4
Journal Article
in
BLOEDVATEN, HART, LONGEN
2024
Baseline characteristics and ICS/LAMA/LABA response in asthma : analyses from the CAPTAIN study
Louis -Philippe Boulet
Carl Abbott
Guy Brusselle
Dawn Edwards
John Oppenheimer
Ian D. Pavord
Emilio Pizzichini
Hironori Sagara
David Slade
Michael E. Wechsler
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2024
Case report : dual monoclonal antibody therapy in chronic rhinosinusitis with nasal polyps and severe eosinophilic asthma : a proteome analysis
Manon Blauwblomme
Philippe Gevaert
Sharon Van Nevel
Sebastian Riemann
Elke Vandewalle
Gabriële Holtappels
Natalie De Ruyck
Lara Derycke
Anne-Sophie Eeckels
Stijn Vanhee
et al.
A2
Journal Article
in
FRONTIERS IN ALLERGY
2024
Clinical course of suspected familial and sporadic idiopathic pulmonary fibrosis : data from the PROOF-Next registry
Antoine Froidure
Benjamin Bondue
Caroline Dahlqvist
Julien Guiot
Natacha Gusbin
Gil Wirtz
Guy Brusselle
Danielle Strens
Hans Slabbynck
Wim A. Wuyts
A1
Journal Article
in
RESPIROLOGY
2024
Clinical relevance of lung function trajectory clusters in middle-aged and older adults
Xander Bertels
James C. Ross
Rosa Faner
Michael H. Cho
M. Arfan Ikram
Guy Brusselle
Lies Lahousse
A1
Journal Article
in
ERJ OPEN RESEARCH
2024
Evaluating β2-agonists as siRNA delivery adjuvants for pulmonary surfactant-coated nanogel inhalation therapy
Pieterjan Merckx
GRIET CONICKX
Evy Blomme
Tania Maes
Ken Bracke
Guy Brusselle
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2024
Exploring the genetics of airflow limitation in lung function across the lifespan : a polygenic risk score study
Natalia Hernandez-Pacheco
Anna Kilanowski
Ashish Kumar
John A. Curtin
Núria Olvera
Sara Kress
Xander Bertels
Lies Lahousse
Laxmi Bhatta
Raquel Granell
et al.
A1
Journal Article
in
ECLINICALMEDICINE
2024
Flemish network on rare connective tissue diseases (CTD) : patient pathways in systemic sclerosis : first steps taken
Yves Piette
Freek Van den Bossche
J. Aerts
N. Aerts
S. Ajeganova
V. Badot
N. Berghen
D. Blockmans
Guy Brusselle
N. Caeyers
et al.
A1
Journal Article
in
ACTA CLINICA BELGICA
2024
Genome-wide association study of preserved ratio impaired spirometry (PRISm)
Daniel H. Higbee
Alvin Lirio
Fergus Hamilton
Raquel Granell
Annah B. Wyss
Stephanie J. London
Traci M. Bartz
Sina A. Gharib
Michael H. Cho
Emily Wan
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2024
Impact of exogenous sex steroids in asthma : interim results of the ENIGI-lung study
Sebastian Riemann
Jeroen Vervalcke
Guy T'Sjoen
Guy Brusselle
C3
Conference
2024
Need for sex-stratified reference values for exhaled nitric oxide as biomarker in chronic cough
Sebastian Riemann
Johnmary Tochukwu Arinze
Andrei Malinovschi
Guy Brusselle
A1
Journal Article
in
ERJ OPEN RESEARCH
2024
Phenotyping of severe asthma in the era of broad-acting anti-asthma biologics
A Bourdin
Guy Brusselle
S Couillard
ML Fajt
LG Heaney
E Israel
PJ McDowell
A Menzies-Gow
N Martin
PD Mitchell
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2024
Respiratory epidemiology in the advancement of precision medicine
Xander Bertels
Lies Lahousse
Guy Brusselle
Dissertation
2024
Revisiting the clinical interpretation of CT-measured pulmonary artery-to-aorta ratio : the Rotterdam study
C. F. Khan
M. Kamran Ikram
Natalie Terzikhan
Guy Brusselle
Daniel Bos
A1
Journal Article
in
ACADEMIC RADIOLOGY
2024
Run-in periods and treatment outcomes in asthma trials : a narrative review
Emilio Pizzichini
Guy Brusselle
Dawn Edwards
Peter G. Gibson
Huib A. Kerstjens
Alison Moore
David Slade
Robert A. Wise
Shiyuan Zhang
A2
Journal Article
in
CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS
2024
Selective replacement of cholesterol with cationic amphiphilic drugs enables the design of lipid nanoparticles with improved RNA delivery
Bram Bogaert
Aliona Debisschop
Thomas Ehouarne
Hannelore Van Eeckhoutte
Joyceline De Volder
An Jacobs
Eline Pottie
Riet De Rycke
Aurélie Crabbé
Pieter Mestdagh
et al.
A1
Journal Article
in
NANO LETTERS
2024
The AGE-RAGE axis associates with chronic pulmonary diseases and smoking in the Rotterdam study
Tianqi Lu
Lies Lahousse
Sara Wijnant
Jinluan Chen
Guy Brusselle
Mandy van Hoek
M. Carola Zillikens
A1
Journal Article
in
RESPIRATORY RESEARCH
2024
The protective role of testosterone and its precursors in asthma and asthma-related symptoms : cross-sectional findings from the Rotterdam Study
Sebastian Riemann
Layal Chaker
Guy Brusselle
C3
Conference
2024
The role of circulating sex hormones in mild-to-moderate asthma : cross-sectional analysis within the Rotterdam Study
Sebastian Riemann
Layal Chaker
Guy Brusselle
C3
Conference
2024
2023
Advanced glycation end products (AGEs) in relation to COPD and lung function : the Rotterdam Study
Tianqi Lu
Lies Lahousse
Sara Wijnant
Jinluan Chen
Guy Brusselle
Mandy Van Hoek
M. Carola Zillikens
C3
Conference
2023
Association of a polygenic risk score for chronic obstructive pulmonary disease with lung function across the lifespan
Natalia Hernandez-Pacheco
Anna Kilanowski
Ashish Kumar
John A. Curtin
Nuria Olvera
Sara Kress
Xander Bertels
Lies Lahousse
Laxmi Bhatta
Raquel Granell
et al.
C3
Conference
2023
Development and validation of an electronic daily control score for asthma (e-DASTHMA) : a real-world direct patient data study
Bernardo Sousa-Pinto
Cristina Jacome
Ana Margarida Pereira
Frederico S. Regateiro
Rute Almeida
Wienczyslawa Czarlewski
Marek Kulus
Mohamed H. Shamji
Louis-Philippe Boulet
Matteo Bonini
et al.
A1
Journal Article
in
LANCET DIGITAL HEALTH
2023
Development of core outcome measures sets for paediatric and adult Severe Asthma (COMSA)
Ekaterina Khaleva
Anna Rattu
Chris Brightling
Andrew Bush
Apostolos Bossios
Arnaud Bourdin
Kian Fan Chung
Rekha Chaudhuri
Courtney Coleman
Sven-Erik Dahlen
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2023
Dupilumab efficacy in patients with uncontrolled or oral corticosteroid-dependent allergic and nonallergic asthma
Guy Brusselle
Santiago Quirce
Alberto Papi
Piotr Kuna
Bradley E. Chipps
Nicola A. Hanania
Michael Blaiss
Jerome Msihid
Juby A. Jacob-Nara
Yamo Deniz
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2023
Effect of stepping up to high-dose inhaled corticosteroids in patients with asthma : UK database study
Ian D Pavord FMedSci
Trung N Tran
Rupert C Jones
Javier Nuevo
Maarten van den Berge
Guy Brusselle
Andrew N Menzies-Gow
Derek Skinner
Victoria Carter
Janwillem W H Kocks
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2023
Frailty transitions in older persons with lung function impairment : a population-based study
Sara Wijnant
Elizabeth Benz
Annemarie I Luik
Fernando Rivadeneira
Trudy Voortman
Guy Brusselle
Lies Lahousse
A1
Journal Article
in
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
2023
Global access and patient safety in the transition to environmentally friendly respiratory inhalers : the Global Initiative for Asthma perspective
Mark L Levy
Eric D Bateman
Keith Allan
Leonard B Bacharier
Matteo Bonini
Louis-Philippe Boulet
Arnaud Bourdin
Chris Brightling
Guy Brusselle
Roland Buhl
et al.
Editorial material
2023
Is efficacy of tezepelumab independent of severe asthma phenotype?
Guy Brusselle
Sebastian Riemann
Editorial material
2023
Long-term efficacy of dupilumab in severe asthma by baseline oral corticosteroid dose
Christian Domingo
Klaus F Rabe
David Price
Guy Brusselle
Michael E. Wechsler
Changming Xia
Nami Pandit-Abid
Rebecca Gall
Paul J. Rowe
Yamo Deniz
et al.
A1
Journal Article
in
ERJ OPEN RESEARCH
2023
Mepolizumab attenuates ILC2s proliferation and activity in adults with severe eosinophilic asthma
Guy Brusselle
Sebastian Riemann
Tania Maes
Editorial material
2023
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
Nick Shrine
Abril G. Izquierdo
Jing Chen
Richard Packer
Robert J. Hall
Anna L. Guyatt
Chiara Batini
Rebecca J. Thompson
Chandan Pavuluri
Vidhi Malik
et al.
A1
Journal Article
in
NATURE GENETICS
2023
Novel genetic variants associated with inhaled corticosteroid treatment response in older adults with asthma
Alberta L. Wang
Lies Lahousse
Amber Dahlin
Ahmed Edris Mohamed
Michael McGeachie
Sharon M. Lutz
Joanne E. Sordillo
Guy Brusselle
Jessica Lasky-Su
Scott T. Weiss
et al.
A1
Journal Article
in
THORAX
2023
Oral corticosteroid use and sarcopenia-related traits in older people with chronic airway disease : a population-based study
Elizabeth Benz
Lies Lahousse
Johnmary Tochukwu Arinze
Sara Wijnant
Maria de Ridder
Fernando Rivadeneira
Guy Brusselle
Bruno H. Stricker
A1
Journal Article
in
ERJ OPEN RESEARCH
2023
Parasitic infections related to anti-type 2 immunity monoclonal antibodies : a disproportionality analysis in the food and drug administration’s adverse event reporting system (FAERS)
Victor Pera
Guy Brusselle
Sebastian Riemann
Jan A. Kors
Erik M. Van Mulligen
Rowan Parry
Marcel de Wilde
Peter R. Rijnbeek
Katia Verhamme
A1
Journal Article
in
FRONTIERS IN PHARMACOLOGY
2023
Phenotyping asthma with airflow obstruction in middle-aged and older adults : a CADSET clinical research collaboration
Xander Bertels
Ahmed Edris Mohamed
Judith Garcia-Aymerich
Rosa Faner
Howraman Meteran
Torben Sigsgaard
Peter Alter
Claus Vogelmeier
Nuria Olvera
Nazanin Zounemat Kermani
et al.
A1
Journal Article
in
BMJ OPEN RESPIRATORY RESEARCH
2023
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD
Hannelore Van Eeckhoutte
Chantal Donovan
Richard Y. Kim
Thomas M. Conlon
Meshal Ansari
Haroon Khan
Ranjith Jayaraman
Nicole G. Hansbro
Yves Dondelinger
Tom Delanghe
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2023
Remission outcomes in severe eosinophilic asthma with mepolizumab therapy : analysis of the REDES study
Ian Pavord
Frances Gardiner
Liam G. Heaney
Christian Domingo
Robert G. Price
Alison Pullan
John Oppenheimer
Guy Brusselle
Hiroyuki Nagase
Geoffrey Chupp
et al.
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2023
Reply to Lipworth and Chan
Sebastian Riemann
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2023
Risk stratifying interstitial lung abnormalities to guide early diagnosis interstitial lung diseases
Marlies S Wijsenbeek
Guy Brusselle
Editorial material
2023
Role of low-dose mepolizumab maintenance therapy in preventing flare-ups in ANCA+ EGPA : a case-report
Sebastian Riemann
Aurelie Vanthuyne
Guy Brusselle
C3
Conference
2023
Safety and effectiveness of as-needed formoterol in asthma patients taking inhaled corticosteroid (ICS)-formoterol or ICS-salmeterol maintenance therapy
Helen Kathryn Reddel
Guy Brusselle
Rosa Lamarca
Per Gustafson
Gary P Anderson
Carin Jorup
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2023
Smoking-related dysregulation of plasma circulating microRNAs : the Rotterdam study
Irma Karabegovic
Silvana C. E. Maas
Yu Shuai
M. Arfan Ikram
Bruno Stricker
Joachim Aerts
Guy Brusselle
Lies Lahousse
Trudy Voortman
Mohsen Ghanbari
A1
Journal Article
in
HUMAN GENOMICS
2023
The role of regulated cell death in chronic obstructive pulmonary disease (COPD)
Hannelore Van Eeckhoutte
Ken Bracke
Guy Brusselle
Tom Vanden Berghe
Dissertation
2023
Trajectory of neutrophilic responses in a mouse model of pollutant-aggravated allergic asthma
Joyceline De Volder
Annelies Bontinck
Katrien De Grove
Iris Dirven
Valerie Haelterman
Guy Joos
Guy Brusselle
Tania Maes
A1
Journal Article
in
ENVIRONMENTAL POLLUTION
2023
Trends in outpatient azithromycin prescribing in respiratory diseases
Victor Pera
Helen Panen
Maria A. J. De Ridder
Lies Lahousse
Guy Brusselle
Peter R. Rijnbeek
Katia Verhamme
C3
Conference
2023
2022
Anti–interleukin-5 therapy is associated with attenuated lung function decline in severe eosinophilic asthma patients from the Belgian Severe Asthma Registry
Sophie Graff
Guy Brusselle
Shane Hanon
Carine Sohy
Lieven Dupont
Rudy Peche
Alain Michils
Charles Pilette
Guy Joos
Lies Lahousse
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2022
Associations of pulmonary function with MRI brain volumes : a coordinated multi-study analysis
Stefan Frenzel
Joshua C. Bis
Elias F. Gudmundsson
Adrienne O'Donnell
Jeannette Simino
Amber Yaqub
Traci M. Bartz
Guy Brusselle
Robin Buelow
Charles S. DeCarlil
et al.
A1
Journal Article
in
JOURNAL OF ALZHEIMERS DISEASE
2022
B cells and their crosstalk with fibroblasts in chronic obstructive pulmonary disease (COPD) : translational research during the COVID-19 pandemic
Merel Jacobs
Ken Bracke
Guy Brusselle
Dissertation
2022
Biologic therapies for severe asthma
Guy Brusselle
Gerard H. Koppelman
A1
Journal Article
in
NEW ENGLAND JOURNAL OF MEDICINE
2022
Changes in lung function in European adults born between 1884 and 1996 and implications for the diagnosis of lung disease : a cross-sectional analysis of ten population-based studies
James P Allinson
Shoaib Afzal
Yunus Çolak
Debbie Jarvis
Helena Backman
Maarten van den Berge
H Marike Boezen
Marie-Kathrin Breyer
Robab Breyer-Kohansal
Guy Brusselle
et al.
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2022
Characterization of asthma by age of onset : a multi-database cohort study
Esme J Baan
Emmely de Roos
Marjolein Engelkes
Maria de Ridder
Lars Pedersen
Klara Berencsi
Dani Prieto-Alhambra
Francesco Lapi
Melissa K Van Dyke
Peter Rijnbeek
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2022
Classification of COPD : fostering prevention and precision medicine in the Lancet Commission on COPD
Guy Brusselle
Marc Humbert
Editorial material
2022
Disease-modifying anti-asthmatic drugs
Marek Lommatzsch
Guy Brusselle
G. Walter Canonica
David J. Jackson
Parameswaran Nair
Roland Buhl
Johann Christian Virchow
Editorial material
2022
ERS statement : a core outcome set for clinical trials evaluating the management of chronic obstructive pulmonary disease (COPD) exacerbations
Alexander G. Mathioudakis
Fekri Abroug
Alvar Agusti
Sachin Ananth
Per Bakke
Konstantinos Bartziokas
Bianca Beghe
Andras Bikov
Thomas Bradbury
Guy Brusselle
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2022
Epidemiology of interstitial lung diseases and their progressive-fibrosing behaviour in six European countries
Ole Hilberg
Anna-Maria Hoffmann-Vold
Vanessa Smith
Demosthenes Bouros
Maritta Kilpeläinen
Julien Guiot
Antonio Morais
Susana Clemente
Zoe Daniil
Despina Papakosta
et al.
A1
Journal Article
in
ERJ OPEN RESEARCH
2022
Genetic associations and architecture of asthma-chronic obstructive pulmonary disease overlap
Catherine John
Anna L. Guyatt
Nick Shrine
Richard Packer
Thorunn A. Olafsdottir
Jiangyuan Liu
Lystra P. Hayden
Su H. Chu
Jukka T. Koskela
Jian’an Luan
et al.
A1
Journal Article
in
CHEST
2022
Global Initiative for Asthma Strategy 2021 : executive summary and rationale for key changes
Helen K. Reddel
Leonard B. Bacharier
Eric D. Bateman
Christopher E. Brightling
Guy Brusselle
Roland Buhl
Alvaro A. Cruz
Liesbeth Duijts
Jeffrey M. Drazen
J. Mark FitzGerald
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2022
Global Initiative for Asthma Strategy 2021 : executive summary and rationale for key changes
Helen K. Reddel
Leonard B. Bacharier
Eric D. Bateman
Christopher E. Brightling
Guy Brusselle
Roland Buhl
Alvaro A. Cruz
Liesbeth Duijts
Jeffrey M. Drazen
J. Mark FitzGerald
et al.
A1
Journal Article
in
ARCHIVOS DE BRONCONEUMOLOGIA
2022
Global Initiative for Asthma Strategy 2021 : executive summary and rationale for key changes
Helen K. Reddel
Leonard B. Bacharier
Eric D. Bateman
Christopher E. Brightling
Guy Brusselle
Roland Buhl
Alvaro A. Cruz
Liesbeth Duijts
Jeffrey M. Drazen
J. Mark FitzGerald
et al.
A1
Journal Article
in
RESPIROLOGY
2022
Global Initiative for Asthma Strategy 2021 : executive summary and rationale for key changes
Helen K. Reddel
Leonard B. Bacharier
Eric D. Bateman
Christopher E. Brightling
Guy Brusselle
Roland Buhl
Alvaro A. Cruz
Liesbeth Duijts
Jeffrey M. Drazen
J. Mark FitzGerald
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2022
Global initiative for Asthma Strategy 2021 : executive summary and rationale for key changes
Helen K. Reddel
Leonard B. Bacharier
Eric D. Bateman
Christopher E. Brightling
Guy Brusselle
Roland Buhl
Alvaro A. Cruz
Liesbeth Duijts
Jeffrey M. Drazen
J. Mark FitzGerald
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2022
IL-10 producing regulatory B cells are decreased in blood from smokers and COPD patients
Merel Jacobs
Sven Verschraegen
Bihiyga Salhi
Jasper Anckaert
Pieter Mestdagh
Guy Brusselle
Ken Bracke
A1
Journal Article
in
RESPIRATORY RESEARCH
2022
Lung function impairment in relation to cognition and vascular brain lesions : the Rotterdam Study
Tian Xiao
Sara Wijnant
Isabelle van der Velpen
Natalie Terzikhan
Lies Lahousse
M. Kamran Ikram
Meike W Vernooij
Guy Brusselle
M. Arfan Ikram
A1
Journal Article
in
JOURNAL OF NEUROLOGY
2022
Multi-ancestry genome-wide association study of asthma exacerbations
Esther Herrera-Luis
Victor E. Ortega
Elizabeth J. Ampleford
Yang Yie Sio
Raquel Granell
Emmely de Roos
Natalie Terzikhan
Ernesto Elorduy Vergara
Natalia Hernandez-Pacheco
Javier Perez-Garcia
et al.
A1
Journal Article
in
PEDIATRIC ALLERGY AND IMMUNOLOGY
2022
NO in de uitgeademde lucht, een overzicht
H. Vanneste
Eric Derom
Guy Brusselle
Guy Joos
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2022
Non-typeable Haemophilus influenzae–Moraxella catarrhalis vaccine for the prevention of exacerbations in chronic obstructive pulmonary disease : a multicentre, randomised, placebo-controlled, observer-blinded, proof-of-concept, phase 2b trial
Guy Brusselle
Tom M A Wilkinson
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2022
Pharmacogenetics of inhaled corticosteroids and exacerbation risk in adults with asthma
Ahmed Edris Mohamed
Emmely de Roos
Michael J. McGeachie
Katia Verhamme
Guy Brusselle
Kelan G. Tantisira
Carlos Iribarren
Meng Lu
Ann Chen Wu
Bruno H. Stricker
et al.
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
2022
Pulmonary function and blood DNA methylation a multiancestry epigenome-wide association meta-analysis
Mikyeong Lee
Tianxiao Huan
Daniel L. McCartney
Geetha Chittoor
Maaike de Vries
Lies Lahousse
Jennifer N. Nguyen
Jennifer A. Brody
Juan Castillo-Fernandez
Natalie Terzikhan
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2022
Pulmonary hypertension in interstitial lung disease : an area of unmet clinical need
Sebastiaan Dhont
Bert Zwaenepoel
Els Vandecasteele
Guy Brusselle
Michel De Pauw
A1
Journal Article
in
ERJ OPEN RESEARCH
2022
Real-life effectiveness of mepolizumab in severe asthma : a systematic literature review
Elliot Israel
Giorgio Walter Canonica
Guy Brusselle
Shibing Yang
Peter H. Howarth
Amber L. Martin
Maria Koufopoulou
Steven G. Smith
Rafael Alfonso-Cristancho
A1
Journal Article
in
JOURNAL OF ASTHMA
2022
Sarcopenia, systemic immune-inflammation index and all-cause mortality in middle-aged and older people with COPD and asthma : a population-based study
Elizabeth Benz
Sara Wijnant
Katerina Trajanoska
Johnmary Tochukwu Arinze
Emmely de Roos
Maria de Ridder
Ross Williams
Frank van Rooij
Katia M. C. Verhamme
M. Arfan Ikram
et al.
A1
Journal Article
in
ERJ OPEN RESEARCH
2022
Serum immunoglobulins, pneumonia risk, and lung function in middle-aged and older individuals : a population-based cohort study
Samer R. Khan
Anna Vanoverschelde
Lies Lahousse
Robin P. Peeters
P. Martin van Hagen
Guy Brusselle
Layal Chaker
Virgil A. S. H. Dalm
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2022
The interrelationship of chronic cough and depression : a prospective population-based study
Johnmary Tochukwu Arinze
Amy Hofman
Emmely de Roos
Maria A. J. de Ridder
Katia Verhamme
Bruno Stricker
Guy Brusselle
Annemarie Luik
A1
Journal Article
in
ERJ OPEN RESEARCH
2022
The low flyers : persistent airflow limitation in young adults
Francesca Polverino
George R. Washko
Ronina A. Covar
Eric B. Hysinger
Tillie L. Hackett
Surya P. Bhatt
Guy Brusselle
Shyamali C. Dharmage
Editorial material
2022
Validation of clinical COPD phenotypes for prognosis of long-term mortality in Swedish and Dutch cohorts
S. Gagatek
Sara Wijnant
B. Stallberg
K. Lisspers
Guy Brusselle
X. Zhou
M. Hasselgren
S. Montgomeryi
J. Sundhj
C. Janson
et al.
A1
Journal Article
in
COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
2022
2021
3TR : a pan-European cross-disease research consortium aimed at improving personalised biological treatment of asthma and COPD
Celeste Porsbjerg
Anke H. Maitland-van der Zee
Guy Brusselle
Giorgio Walter Canonica
Alvar Agusti
Rosa Faner
Claus F. Vogelmeier
Martijn Nawijn
Maarten van den Berge
Franca Rusconi
et al.
Editorial material
2021
A microRNA-21–mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis
Richard Y. Kim
Krishna P. Sunkara
Ken R. Bracke
Andrew G. Jarnicki
Chantal Donovan
Alan C. Hsu
Antonio Ieni
Emma L. Beckett
Izabela Galvão
Sara Wijnant
et al.
A1
Journal Article
in
SCIENCE TRANSLATIONAL MEDICINE
2021
A systematic analysis of protein-altering exonic variants in chronic obstructive pulmonary disease
Matthew Moll
Victoria E. Jackson
Bing Yu
Megan L. Grove
Stephanie J. London
Sina A. Gharib
Traci M. Bartz
Colleen M. Sitlani
Josee Dupuis
George T. O'Connor
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
2021
ARIA digital anamorphosis : digital transformation of health and care in airway diseases from research to practice
Jean Bousquet
Josep M. Anto
Claus Bachert
Tari Haahtela
Torsten Zuberbier
Wienczyslawa Czarlewski
Anna Bedbrook
Sinthia Bosnic-Anticevich
G. Walter Canonica
Victoria Cardona
et al.
A1
Journal Article
in
ALLERGY
2021
Beclometasone dipropionate/formoterol maintenance and reliever therapy asthma exacerbation benefit increases with blood eosinophil level
Guy Brusselle
Gabriele Nicolini
Luigi Santoro
Daniele Guastalla
Alberto Papi
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2021
Cluster analysis of inflammatory biomarker expression in the International Severe Asthma Registry (ISAR)
E. Denton
D. Price
T. Tran
G. Canonica
A. Menzies-Gow
J. Fitzgerald
M. Sadatsafavi
L. Prerez De Llano
G. Christoff
A. Quinton
et al.
C3
Conference
2021
Cluster analysis of inflammatory biomarker expression in the international severe asthma registry
Eve Denton
David B. Price
Trung N. Tran
G. Walter Canonica
Andrew Menzies-Gow
J. Mark FitzGerald
Mohsen Sadatsafavi
Luis Perez de Llano
George Christoff
Anna Quinton
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2021
Comparison of cerebral blood flow in subjects with and without chronic obstructive pulmonary disease from the population-based Rotterdam Study
Sara Wijnant
Daniel Bos
Guy Brusselle
Maxim Grymonprez
Ernst Rietzschel
Meike W. Vernooij
Natalie Terzikhan
Lies Lahousse
A1
Journal Article
in
BMJ OPEN
2021
Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
Merel Jacobs
Lies Lahousse
Hannelore Van Eeckhoutte
Sara Wijnant
Joris Delanghe
Guy Brusselle
Ken Bracke
A1
Journal Article
in
ERJ OPEN RESEARCH
2021
Effect of beta-blockers on the risk of COPD exacerbations according to indication of use : the Rotterdam Study
Leila Karimi
Lies Lahousse
Phebe De Nocker
Bruno H. Stricker
Guy Brusselle
Katia Verhamme
A1
Journal Article
in
ERJ OPEN RESEARCH
2021
Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN) : a double-blind, randomised, phase 3A trial
Laurie A Lee
Zelie Bailes
Neil Barnes
Louis-Philippe Boulet
Dawn Edwards
Andrew Fowler
Nicola A Hanania
Huib A M Kerstjens
Edward Kerwin
Robert Nathan
et al.
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2021
Eosinophilic and noneosinophilic asthma : an expert consensus framework to characterize phenotypes in a global real-life severe asthma cohort
Liam G. Heaney
Luis Perez de Llano
Mona Al-Ahmad
Vibeke Backer
John Busby
Giorgio Walter Canonica
George C. Christoff
Borja G. Cosio
J. Mark FitzGerald
Enrico Heffler
et al.
A1
Journal Article
in
CHEST
2021
Epigenome-wide association study on diffusing capacity of the lung
Natalie Terzikhan
Hanfei Xu
Ahmed Edris Mohamed
Ken Bracke
Fien Verhamme
Bruno H. C. Stricker
Josée Dupuis
Lies Lahousse
George T. O'Connor
Guy Brusselle
A1
Journal Article
in
ERJ OPEN RESEARCH
2021
Incidence and predictors of asthma exacerbations in middleaged and older adults : the Rotterdam Study
Emmely de Roos
Lies Lahousse
Katia Verhamme
Gert-Jan Braunstahl
Johannes J. C. C. M. in 't Veen
Bruno H. Stricker
Guy Brusselle
A1
Journal Article
in
ERJ OPEN RESEARCH
2021
Incidence, prevalence and long-term progression of Goh algorithm rated interstitial lung disease in systemic sclerosis in two independent cohorts in flanders : a retrospective cohort study
Els Vandecasteele
Karin Melsens
Amber Vanhaecke
Daniel Blockmans
Carolien Bonroy
Charlotte Carton
Ellen Deschepper
Filip De Keyser
Frederic Houssiau
Yves Piette
et al.
A1
Journal Article
in
SEMINARS IN ARTHRITIS AND RHEUMATISM
2021
Lung function impairment and the risk of incident dementia : the Rotterdam study
Tian Xiao
Sara Wijnant
Silvan Licher
Natalie Terzikhan
Lies Lahousse
M. Kamran Ikram
Guy Brusselle
M. Arfan Ikram
A1
Journal Article
in
JOURNAL OF ALZHEIMERS DISEASE
2021
Mepolizumab for chronic rhinosinusitis with nasal polyps
Guy Brusselle
Philippe Gevaert
Editorial material
2021
MiR-223 is increased in lungs of patients with COPD and modulates cigarette smoke-induced pulmonary inflammation
Mirjam Roffel
Tania Maes
Corry-Anke Brandsma
Maarten van den Berge
Bart M. Vanaudenaerde
Guy Joos
Guy Brusselle
Irene H. Heijink
Ken Bracke
A1
Journal Article
in
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
2021
Necroptosis signalling promotes inflammation, airway remodelling and emphysema in COPD
Zhe Lu
Hannelore Van Eeckhoutte
Gang Liu
Prema M Nair
Bernadette Jones
Caitlin Gillis
B. Christina Nalkurthi
Fien Verhamme
Tamariche Buyle-Huybrecht
Peter Vandenabeele
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2021
Patient characteristics, biomarkers, and exacerbation risk in severe, uncontrolled asthma
Monica Kraft
Guy Brusselle
J. Mark FitzGerald
Ian D. Pavord
Matthew Keith
Malin Fagerås
Esther Garcia Gil
Ian Hirsch
Mitchell Goldman
Gene Colice
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2021
Phenotyping adults with impaired pulmonary function in the era of precision medicine
Sara Wijnant
Guy Brusselle
Lies Lahousse
Ernst Rietzschel
Dissertation
2021
Quantification and role of innate lymphoid cell subsets in Chronic Obstructive Pulmonary Disease
Evy Blomme
Sharen Provoost
Elise De Smet
Katrien De Grove
Hannelore Van Eeckhoutte
Joyceline De Volder
Philip M Hansbro
Matteo Bonato
Marina Saetta
Sara Wijnant
et al.
A1
Journal Article
in
CLINICAL & TRANSLATIONAL IMMUNOLOGY
2021
Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function
Tianzhong Yang
Victoria E. Jackson
V Smith, Albert
Han Chen
Traci M. Bartz
Colleen M. Sitlani
Bruce M. Psaty
Sina A. Gharib
George T. O'Connor
Josee Dupuis
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2021
Sarcopenia in older people with chronic airway diseases : the Rotterdam study
Elizabeth Benz
Katerina Trajanoska
Josje D. Schoufour
Lies Lahousse
Emmely de Roos
Natalie Terzikhan
Carolina Medina-Gomez
Katia Verhamme
Ross Williams
Bruno H. Stricker
et al.
A1
Journal Article
in
ERJ OPEN RESEARCH
2021
The ALPACA study : (in)appropriate LAMA prescribing in asthma : a cohort analysis
E. J. Baan
C. E. Hoeve
M. De Ridder
L. Demoen
Lies Lahousse
Guy Brusselle
Katia Verhamme
A1
Journal Article
in
PULMONARY PHARMACOLOGY & THERAPEUTICS
2021
The interrelatedness of chronic cough and chronic pain
Johnmary Tochukwu Arinze
Katia Verhamme
Annemarie I. Luik
Bruno Stricker
Joyce B. J. van Meurs
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2021
Treatment options in type-2 low asthma
Timothy S.C. Hinks
Stewart J. Levine
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2021
2020
A cross-omics integrative study of metabolic signatures of chronic obstructive pulmonary disease
Ivana Prokic
Lies Lahousse
Maaike de Vries
Jun Liu
Marita Kalaoja
Judith M. Vonk
Diana van der Plaat
Cleo van Diemen
Ashley van der Spek
Alexandra Zhernakova
et al.
A1
Journal Article
in
BMC PULMONARY MEDICINE
2020
A new once-daily long-acting beta(2)-adrenoceptor agonist-inhaled corticosteroid combination therapy for asthma
Guy Brusselle
Editorial material
2020
Blood eosinophil level and lung function trajectories : cross-sectional and longitudinal studies in European cohorts
Ida Mogensen
Judith M. Vonk
Sara Wijnant
Xingwu Zhou
H. Marike Boezen
Guy Brusselle
Lies Lahousse
Christer Janson
Andrei Malinovschi
A1
Journal Article
in
ERJ OPEN RESEARCH
2020
COVID-19 and biologics in severe asthma : data from the Belgian Severe Asthma Registry
Shane Hanon
Guy Brusselle
Maud Deschampheleire
Renaud Louis
Alain Michils
Rudi Peche
Charles Pilette
Peter Rummens
Daniel Schuermans
Helene Simonis
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2020
COVID-19, asthma, and inhaled corticosteroids : another beneficial effect of inhaled corticosteroids?
Tania Maes
Ken Bracke
Guy Brusselle
Editorial material
2020
Change in blood eosinophils following treatment with inhaled corticosteroids may predict long-term clinical response in COPD
Alexander G. Mathioudakis
Andras Bikov
Philip Foden
Lies Lahousse
Guy Brusselle
Dave Singh
Jorgen Vestbo
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2020
Charting extracellular transcriptomes in the human biofluid RNA atlas
Eva Hulstaert
Annelien Morlion
Francisco Avila Cobos
Kimberly Verniers
Justine Nuytens
Eveline Vanden Eynde
Nurten Yigit
Jasper Anckaert
Anja Geerts
Pieter Hindryckx
et al.
A1
Journal Article
in
CELL REPORTS
2020
Chronic obstructive pulmonary disease and related phenotypes : polygenic risk scores in population-based and case-control cohorts
Matthew Moll
Phuwanat Sakornsakolpat
Nick Shrine
Brian D. Hobbs
Dawn L. DeMeo
Catherine John
Anna L. Guyatt
Michael J. McGeachie
Sina A. Gharib
Ma'en Obeidat
et al.
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2020
Chronic oral corticosteroids use and persistent eosinophilia in severe asthmatics from the Belgian severe asthma registry
Simon Graff
Sarah Vanwynsberghe
Guy Brusselle
S. Hanon
C. Sohy
L. J. Dupont
R. Peche
A. Michils
C. Pilette
Guy Joos
et al.
A1
Journal Article
in
RESPIRATORY RESEARCH
2020
Core outcome set for the management of acute exacerbations of chronic obstructive pulmonary disease : the COS-AECOPD ERS Task Force study protocol
Alexander G. Mathioudakis
Fekri Abroug
Alvar Agusti
Per Bakke
Konstantinos Bartziokas
Bianca Beghe
Andras Bikov
Thomas Bradbury
Guy Brusselle
Cordula Cadus
et al.
A1
Journal Article
in
ERJ OPEN RESEARCH
2020
Effect of fixed-dose subcutaneous reslizumab on asthma exacerbations in patients with severe uncontrolled asthma and corticosteroid sparing in patients with oral corticosteroid-dependent asthma : results from two phase 3, randomised, double-blind, placebo-controlled trials
Jonathan A Bernstein
J Christian Virchow
Kevin Murphy
Jorge Fernando Maspero
Joshua Jacobs
Yochai Adir
Marc Humbert
Mario Castro
Douglas A Marsteller
Jennifer McElhattan
et al.
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2020
Expanding the spectrum of European Respiratory Society official scientific documents : short documents complement clinical practice guidelines, statements and technical standards
Nicolas Roche
Thomy Tonia
Marc Miravitlles
Valerie Vaccaro
Celine Genton
Tobias Welte
Thierry Troosters
Guy Brusselle
Chris Brightling
Editorial material
2020
Expression of ACE2, the SARS-CoV-2 receptor, in lung tissue of patients with type 2 diabetes
Sara Wijnant
Merel Jacobs
Hannelore Van Eeckhoutte
Bruno Lapauw
Guy Joos
Ken Bracke
Guy Brusselle
A1
Journal Article
in
DIABETES
2020
F-ENO as a biomarker guide for inhaled corticosteroid step down in patients with mild-to-moderate well-controlled asthma
Anh Tuan Dinh-Xuan
Guy Brusselle
Editorial material
2020
GINA fosters World Asthma Day 2020 to prevent asthma deaths
Louis-Philippe Boulet
Helen K. Reddel
Chris Brightling
Guy Brusselle
Editorial material
2020
Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects
Merel Jacobs
Hannelore Van Eeckhoutte
Sara Wijnant
Wim Janssens
Guy Joos
Guy Brusselle
Ken Bracke
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2020
Inhaled corticosteroids and COVID-19 reply
Tania Maes
Ken Bracke
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2020
Innate defense proteins BPIFA1/B1 and microRNAs in the pathogenesis of COPD
Elise De Smet
Guy Brusselle
Ken Bracke
Pieter Mestdagh
Dissertation
2020
Innate lymphoid cells in isocyanate-induced asthma : role of microRNA-155
Evy Blomme
Sharen Provoost
Erica Bazzan
Hannelore Van Eeckhoutte
Mirjam Roffel
Lore Pollaris
Annelies Bontinck
Matteo Bonato
Louise Vandenbroucke
Fien Verhamme
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2020
Innate lymphoid cells in the pathogenesis of asthma and COPD
Evy Blomme
Tania Maes
Guy Brusselle
Dissertation
2020
International severe asthma registry (ISAR) : protocol for a global registry
J. Mark FitzGerald
Trung N. Tran
Marianna Alacqua
Alan Altraja
Vibeke Backer
Leif Bjermer
Unnur Bjornsdottir
Arnaud Bourdin
Guy Brusselle
Lakmini Bulathsinhala
et al.
A1
Journal Article
in
BMC MEDICAL RESEARCH METHODOLOGY
2020
International severe asthma registry mission statement
G. Walter Canonica
Marianna Alacqua
Alan Altraja
Vibeke Backer
Elisabeth Bel
Leif Bjermer
Unnur Bjornsdottir
Arnaud Bourdin
Guy Brusselle
George C. Christoff
et al.
A1
Journal Article
in
CHEST
2020
Multinational cohort study of mortality in patients with asthma and severe asthma
Marjolein Engelkes
Maria A. J. de Ridder
Elisabeth Svensson
Klara Berencsi
Daniel Prieto-Alhambra
Francesco Lapi
Carlo Giaquinto
Gino Picelli
Nada Boudiaf
Frank C. Albers
et al.
A1
Journal Article
in
RESPIRATORY MEDICINE
2020
Next-generation Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence
Jean Bousquet
Holger J Schünemann
Akdis Togias
Claus Bachert
Martina Erhola
Peter Hellings
Ludger Klimek
Oliver Pfaar
Dana Wallace
Ignacio Ansotegui
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2020
Objectives, design and main findings until 2020 from the Rotterdam Study
M. Arfan Ikram
Guy Brusselle
Mohsen Ghanbari
Andre Goedegebure
M. Kamran Ikram
Maryam Kavousi
Brenda C. T. Kieboom
Caroline C. W. Klaver
Robert J. de Knegt
Annemarie I. Luik
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF EPIDEMIOLOGY
2020
Prevalence and incidence of, and risk factors for chronic cough in the adult population : the Rotterdam Study
Johnmary T. Arinze
Emmely W. de Roos
Leila Karimi
Katia Verhamme
Bruno H. Stricker
Guy Brusselle
A1
Journal Article
in
ERJ OPEN RESEARCH
2020
Recent advances in chronic obstructive pulmonary disease pathogenesis : from disease mechanisms to precision medicine
Corry-Anke Brandsma
Maarten Van den Berge
Tillie-Louise Hackett
Guy Brusselle
Wim Timens
A1
Journal Article
in
JOURNAL OF PATHOLOGY
2020
Safety of reslizumab in uncontrolled asthma with eosinophilia : a pooled analysis from 6 trials
J. Christian Virchow
Rohit Katial
Guy Brusselle
Yael Shalit
Margaret Garin
Mirna McDonald
Mario Castro
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2020
Severe eosinophilic asthma with nasal polyposis : a phenotype for improved sinonasal and asthma outcomes with mepolizumab therapy
Peter Howarth
Geoffrey Chupp
Linda M. Nelsen
Eric S. Bradford
Daniel J. Bratton
Steven G. Smith
Frank C. Albers
Guy Brusselle
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2020
The global significance of PRISm : how data from low- and middle-income countries link physiology to inflammation
Sara Wijnant
Lies Lahousse
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2020
The impact of the prostaglandin D₂ receptor 2 and its downstream effects on the pathophysiology of asthma
Christopher E Brightling
Guy Brusselle
Pablo Altman
A1
Journal Article
in
ALLERGY
2020
The role of miR-155 in cigarette smoke-induced pulmonary inflammation and COPD
Elise De Smet
Hannelore Van Eeckhoutte
Francisco Avila Cobos
Evy Blomme
Fien Verhamme
Sharen Provoost
STIJN VERLEDEN
Koen Venken
Tania Maes
Guy Joos
et al.
A1
Journal Article
in
MUCOSAL IMMUNOLOGY
2020
Trajectory and mortality of preserved ratio impaired spirometry : the Rotterdam Study
Sara Wijnant
Emmely de Roos
Maryam Kavousi
Bruno Hugo Stricker
Natalie Terzikhan
Lies Lahousse
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2020
Translational research into the effects of cigarette smoke on inflammatory mediators and epithelial TRPV1 in Crohn’s disease
Liesbeth Allais
Stephanie Verschuere
Tania Maes
Rebecca De Smet
Sarah Devriese
Bryan Gonzales
Harald Peeters
Koen Van Crombruggen
Claus Bachert
Martine De Vos
et al.
A1
Journal Article
in
PLOS ONE
2020
2019
Adherence to controller therapy in chronic obstructive pulmonary disease : real life setting
Leila Karimi
Esme J Baan
Tiana Geeraerd
Johan Van der Lei
Bruno HC Stricker
Guy Brusselle
Lies Lahousse
Katia M Verhamme
C3
Conference
2019
Adherence trajectories in asthmatic patients
Esme Baan
Leila Karimi
Astrid Heeremans
Guy Brusselle
Miriam Sturkenboom
Hettie M Janssens
Lies Lahousse
Johan C de Jongste
Katia Verhamme
C3
Conference
2019
Association between inhaled corticosteroid therapy for COPD and diabetes onset and progression
K Kostikas
J Voorham
N Roche
J Stephens
H Park
R Fogel
A Clemens
Guy Brusselle
D Price
C3
Conference
2019
Association of alcohol consumption with allergic disease and asthma : a multi-centre Mendelian randomization analysis
Tea Skaaby
Tuomas O. Kilpelainen
Amy E. Taylor
Yuvaraj Mahendran
Andrew Wong
Tarunveer S. Ahluwalia
Lavinia Paternoster
Stella Trompet
David J. Stott
Claudia Flexeder
et al.
A1
Journal Article
in
ADDICTION
2019
Association of elevated fractional exhaled nitric oxide concentration and blood eosinophil count with severe asthma exacerbations
David B Price
Sinthia Bosnic-Anticevich
Ian D Pavord
Nicolas Roche
David MG Halpin
Leif Bjermer
Omar S Usmani
Guy Brusselle
Simon Wan Yau Ming
Sarang Rastogi
A1
Journal Article
in
CLINICAL AND TRANSLATIONAL ALLERGY
2019
Atherosclerotic calcification in major vessel beds in chronic obstructive pulmonary disease : the Rotterdam Study
Lies Lahousse
Daniel Bos
Sara Wijnant
Maryam Kavousi
Bruno H. Stricker
Aad van der Lugt
Meike W. Vernooij
Guy Brusselle
A1
Journal Article
in
ATHEROSCLEROSIS
2019
Azithromycin during acute chronic obstructive pulmonary disease exacerbations requiring hospitalization (BACE) : a multicenter, randomized, double-blind, placebo-controlled trial
Kristina Vermeersch
Maria Gabrovska
Joseph Aumann
Ingel K Demedts
Jean-Louis Corhay
Eric Marchand
Hans Slabbynck
Christel Haenebalcke
Michiel Haerens
Shane Hanon
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2019
Beta(2)-adrenergic receptor (ADRB2) gene polymorphisms and risk of COPD exacerbations : the Rotterdam study
Leila Karimi
Lies Lahousse
Mohsen Ghanbari
Natalie Terzikhan
Andre G. Uitterlinden
Johan van der Lei
Guy Brusselle
Bruno H. Stricker
Katia Verhamme
A1
Journal Article
in
JOURNAL OF CLINICAL MEDICINE
2019
Bone morphogenetic protein 6 (BMP-6) modulates lung function, pulmonary iron levels and cigarette smoke-induced inflammation
Fien Verhamme
Elise De Smet
Wannes Van Hooste
Joris Delanghe
SE Verleden
Guy Joos
Guy Brusselle
Ken Bracke
A1
Journal Article
in
MUCOSAL IMMUNOLOGY
2019
Chronic Airway Diseases Early Stratification (CADSET) : a new ERS clinical research collaboration
Alvar Agusti
Rosa Faner
Gavin Donaldson
Elise Heuvelin
Robab Breyer-Kohansal
Erik Melen
Anke H Maitland-van der Zee
Jorgen Vestbo
James P Allinson
Lowie EGW Vanfleteren
et al.
Editorial material
2019
Chronic obstructive pulmonary disease and the development of atrial fibrillation
Maxim Grymonprez
Vincent Vakaet
Maryam Kavousi
Bruno H Stricker
M Arfan Ikram
Jan Heeringa
Oscar H Franco
Guy Brusselle
Lies Lahousse
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CARDIOLOGY
2019
Chronic use of oral corticosteroids in severe asthmatics in the Belgian Severe Asthma Registry (BSAR)
S Vanwynsberghe
F Schleich
R Louis
O Vandenplas
C Pilette
R Peche
Guy Joos
S Dobbelaere
D Schuermans
S Hanon
et al.
C3
Conference
2019
DNA methylation is associated with lung function in never smokers
Maaike de Vries
Ivana Nedeljkovic
Diana A. van der Plaat
Alexandra Zhernakova
Lies Lahousse
Guy Brusselle
Najaf Amin
Cornelia M. van Duijn
Judith M. Vonk
H. Marike Boezen
A1
Journal Article
in
RESPIRATORY RESEARCH
2019
Does maintenance azithromycin reduce asthma exacerbations? : an individual participant data meta-analysis
Sarah A Hiles
Vanessa M McDonald
Michelle Guilhermino
Guy Brusselle
Peter G Gibson
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2019
Dupilumab effect on asthma control and health-related quality of life in patients with oral corticosteroid-dependent severe asthma with comorbid chronic rhinosinusitis with and without nasal polyps
M Castro
KF Rabe
Guy Brusselle
MS Rice
P Rowe
Y Deniz
S Kamat
A Khan
C3
Conference
2019
ERS/EAACI statement on severe exacerbations in asthma in adults : facts, priorities and key research questions
Arnaud Bourdin
Leif Bjermer
Christopher Brightling
Guy Brusselle
Pascal Chanez
Kian Fan Chung
Adnan Custovic
Zuzana Diamant
Sarah Diver
Ratko Djukanovic
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2019
Effect of a 3-month low-dose azithromycin intervention for COPD exacerbations requiring hospitalization on subsequent respiratory events and mortality : the BACE trial
W Janssens
K Vermeersch
T Troosters
Guy Brusselle
C3
Conference
2019
Efficacy of mepolizumab in patients with severe eosinophilic asthma by age of asthma onset : meta-analysis of two phase III trials
FC Albers
NA Hanania
M Kraft
DJ Bratton
E Bradford
SG Smith
CM Prazma
Guy Brusselle
C3
Conference
2019
Exacerbation rate reduction according to baseline blood eosinophilic count in patients with asthma treated with ICS/LABA maintenance and reliever therapy
Guy Brusselle
A Papi
G Nicolini
L Santoro
D Guastalla
C3
Conference
2019
Expression of receptor interacting protein kinase-3 and mixed lineage kinase domain-like protein in patients with COPD
Fien Verhamme
Hannelore Van Eeckhoutte
T Buyle-Huybrecht
Guy Brusselle
Peter Vandenabeele
Tom Vanden Berghe
Ken Bracke
C3
Conference
2019
GDF-15 in pulmonary and critical care medicine
Fien Verhamme
Christine M Freeman
Guy Brusselle
Ken Bracke
Jeffrey L Curtis
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
2019
GINA 2019 : a fundamental change in asthma management
Helen K Reddel
J Mark FitzGerald
Eric D Bateman
Leonard B Bacharier
Allan Becker
Guy Brusselle
Roland Buhl
Alvaro A Cruz
Louise Fleming
Hiromasa Inoue
et al.
Editorial material
2019
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
Phuwanat Sakornsakolpat
Dmitry Prokopenko
Maxime Lamontagne
Nicola F Reeve
Anna L Guyatt
Victoria E Jackson
Nick Shrine
Dandi Qiao
Traci M Bartz
Deog Kyeom Kim
et al.
A1
Journal Article
in
NATURE GENETICS
2019
Guidance to 2018 good practice : ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma
J Bousquet
A Bedbrook
W Czarlewski
GL Onorato
S Arnavielhe
D Laune
E Mathieu-Dupas
J Fonseca
E Costa
O Lourenco
et al.
A1
Journal Article
in
CLINICAL AND TRANSLATIONAL ALLERGY
2019
Lifetime risk and multimorbidity of non-communicable diseases and disease-free life expectancy in the general population : a population-based cohort study
Silvan Licher
Alis Heshmatollah
Kimberly D van der Willik
Bruno HCh Stricker
Rikje Ruiter
Emmely W de Roos
Lies Lahousse
Peter J Koudstaal
Albert Hofman
Lana Fani
et al.
A1
Journal Article
in
PLOS MEDICINE
2019
Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population
Diana A van der Plaat
Judith M Vonk
Lies Lahousse
Kim de Jong
Alen Faiz
Ivana Nedeljkovic
Najaf Amin
Cleo C van Diemen
Guy Brusselle
Yohan Bosse
et al.
A1
Journal Article
in
BMC PULMONARY MEDICINE
2019
Long-term safety and clinical benefit of mepolizumab in patients with the most severe eosinophilic asthma : the COSMEX study
Sandhya Khurana
Guy Brusselle
Elisabeth H. Bel
J. Mark FitzGerald
Matthew Masoli
Stephanie Korn
Motokazu Kato
Frank C. Albers
Eric S. Bradford
Martyn J. Gilson
et al.
A1
Journal Article
in
CLINICAL THERAPEUTICS
2019
Modulation of innate lymphoid cell subsets in a mouse model of isocyanate-induced asthma
Evy Blomme
Sarah Provoost
L Pollaris
Hannelore Van Eeckhoutte
L Vandenbroucke
Fien Verhamme
Guy Joos
Guy Brusselle
J Vanoirbeek
Tania Maes
C3
Conference
2019
Moving forward from drug-centred to patient-centred research
Denis Lacombe
Colm O'Morain
Barbara Casadei
Kate Hill
Elsa Mateus
Rik Lories
Guy Brusselle
Editorial material
2019
Necroptosis is activated in and drives pathogenesis of COPD
M Fricker
Z Lu
Hannelore Van Eeckhoutte
G Liu
Fien Verhamme
T Buyle-Huybrecht
Guy Brusselle
J Murphy
Ken Bracke
P Hansbro
C3
Conference
2019
Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course
Herman T den Dekker
Kimberley Burrows
Janine F Felix
Lucas A Salas
Ivana Nedeljkovic
Jin Yao
Sheryl L Rifas-Shiman
Carlos Ruiz-Arenas
N Amin
Mariona Bustamante
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2019
Next-generation ARIA care pathways for rhinitis and asthma : a model for multimorbid chronic diseases
J Jean Bousquet
Holger J Schunemann
Alkis Togias
Marina Erhola
Peter W Hellings
Torsten Zuberbier
Ioana Agache
Ignacio J Ansotegui
Josep M Anto
Claus Bachert
et al.
A1
Journal Article
in
CLINICAL AND TRANSLATIONAL ALLERGY
2019
Next-generation care pathways for allergic rhinitis and asthma multimorbidity : a model for multimorbid non-communicable diseases : meeting report (part 1)
Jean Bousquet
Nhan Pham-Thi
Anna Bedbrook
Ioana Agache
Isabella Annesi-Maesano
Ignacio Ansotegui
Josep M Anto
Claus Bachert
Samuel Benveniste
Mike Bewick
et al.
A1
Journal Article
in
JOURNAL OF THORACIC DISEASE
2019
Next-generation care pathways for allergic rhinitis and asthma multimorbidity : a model for multimorbid non-communicable diseases : meeting report (part 2)
Jean Bousquet
Nhan Pham-Thi
Anna Bedbrook
Ioana Agache
Isabella Annesi-Maesano
Ignacio Ansotegui
Josep M Anto
Claus Bachert
Samuel Benveniste
Mike Bewick
et al.
A1
Journal Article
in
JOURNAL OF THORACIC DISEASE
2019
Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression
Diana van Der Plaat
Judith M Vonk
Natalie Terzikhan
Kim de Jong
Maaike de Vries
Sacha La Bastide-van Gemert
Cleo C van Diemen
Lies Lahousse
Guy Brusselle
Ivana Nedeljkovic
et al.
A1
Journal Article
in
HUMAN MOLECULAR GENETICS
2019
Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma
Paraskevi Katsaounou
Roland Buhl
Guy Brusselle
Pascal Pfister
Rafael Martinez
Ulrich Wahn
Jean Bousquet
A1
Journal Article
in
RESPIRATORY MEDICINE
2019
Omega-3 fatty acids and genome-wide interaction analyses reveal DPP10-pulmonary function association
Jiayi Xu
Nathan C Gaddis
Traci M Bartz
Ruixue Hou
Ani W Manichaikul
Nathan Pankratz
Albert V Smith
Fangui Sun
Natalie Terzikhan
Christina A Markunas
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2019
Prevalence and burden of asthma in China : time to act
Guy Brusselle
Fanny Wai-San Ko
Editorial material
2019
Prevalence and characteristics of asthma-chronic obstructive pulmonary disease overlap in routine primary care practices
Jerry A Krishnan
Anjan Nibber
Alison Chisholm
David Price
Eric D Bateman
Leif Bjermer
Job FM van Boven
Guy Brusselle
Richard W Costello
Ronald J Dandurand
et al.
A1
Journal Article
in
ANNALS OF THE AMERICAN THORACIC SOCIETY
2019
Prevalence of asthma and COPD and blood eosinophil count in a middle-aged Belgian population
Sara Wijnant
Lies Lahousse
Marc De Buyzere
Guy Brusselle
Ernst Rietzschel
A1
Journal Article
in
JOURNAL OF CLINICAL MEDICINE
2019
Quality standards in respiratory real-life effectiveness research : the REal Life EVidence AssessmeNt Tool (RELEVANT) : report from the Respiratory Effectiveness Group - European Academy of Allergy and Clinical Immunology Task Force
Nicolas Roche
Jonathan D Campbell
Jerry A Krishnan
Guy Brusselle
Alison Chisholm
Leif Bjermer
Mike Thomas
Eric van Ganse
Maarten van den Berge
George Christoff
et al.
A1
Journal Article
in
CLINICAL AND TRANSLATIONAL ALLERGY
2019
Real-life effectiveness of omalizumab in difficult-to-treat versus severe asthma : a national cohort study in Belgium
Katia Verhamme
Catherine Lucet
Alain Van Meerhaeghe
Guy Brusselle
Marie-Laurence Lambert
A1
Journal Article
in
ERJ OPEN RESEARCH
2019
Sarcopenia in COPD : a systematic review and meta-analysis
Elizabeth Benz
Katerina Trajanoska
Lies Lahousse
Josje D Schoufour
Natalie Terzikhan
Emmely de Roos
Gerdien B de Jonge
Ross Williams
Oscar H Franco
Guy Brusselle
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY REVIEW
2019
Simultaneous inhibition of thymic stromal lymphopoietin, IL-33 and IL-25 : a therapeutic option in asthma?
Tania Maes
Guy Brusselle
Editorial material
2019
The ERS fellowship portfolio : fostering excellence and diversity
Rory E Morty
Louise E Donnelly
Daiana Stolz
Nicolas Roche
Tobias Welte
Kathryn A Forrest
Christopher E Brightling
Guy Brusselle
Editorial material
2019
The REal Life EVidence AssessmeNt Tool (RELEVANT) : development of a novel quality assurance asset to rate observational comparative effectiveness research studies
Jonathan D Campbell
Robert Perry
Nikolaos G Papadopoulos
Jerry Krishnan
Guy Brusselle
Alison Chisholm
Leif Bjermer
Michael Thomas
Eric van Ganse
Maarten van den Berge
et al.
A1
Journal Article
in
CLINICAL AND TRANSLATIONAL ALLERGY
2019
The association between dietary protein intake, energy intake and physical frailty : results from the Rotterdam Study
Josje D Schoufour
Oscar H Franco
Jessica C Kiefte-de Jong
Katerina Trajanoska
Bruno Stricker
Guy Brusselle
Fernando Rivadeneira
Lies Lahousse
Trudy Voortman
A1
Journal Article
in
BRITISH JOURNAL OF NUTRITION
2019
The human biofluid RNA atlas : expanding the liquid biopsy field beyond the blood stream
Eva Hulstaert
Kimberly Verniers
Justine Nuytens
Eveline Vanden Eynde
Nurten Yigit
Jasper Anckaert
Anja Geerts
Peggy Jacques
Guy Brusselle
THIERRY DERVEAUX
et al.
C3
Conference
2019
The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD : current evidence and future prospects
Eric Derom
Guy Brusselle
Guy Joos
A1
Journal Article
in
THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE
2019
Tralokinumab did not demonstrate oral corticosteroid-sparing effects in severe asthma
William W Busse
Guy Brusselle
Stephanie Korn
Piotr Kuna
Antoine Magnan
David Cohen
Karin Bowen
Teresa Piechowiak
Millie M Wang
Gene Colice
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2019
Treatment failure and hospital readmissions in severe COPD exacerbations treated with azithromycin versus placebo - a post-hoc analysis of the BACE randomized controlled trial
Kristina Vermeersch
Ann Belmans
Kris Bogaerts
Iwein Gyselinck
Nina Cardinaels
Maria Gabrovska
Joseph Aumann
Ingel K. Demedts
Jean-Louis Corhay
Eric Marchand
et al.
A1
Journal Article
in
RESPIRATORY RESEARCH
2019
Update on immunogenicity in severe asthma : experience with mepolizumab
Hector G Ortega
Erik Meyer
Guy Brusselle
Koichiro Asano
Charlene M Prazma
Frank C Albers
Stephen A Mallett
Steve W Yancey
Gerald J Gleich
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2019
Variability in total serum IgE over 1 year in severe asthmatics
Renaud Louis
Charles Pilette
Olivier Michel
Alain Michils
Guy Brusselle
Antoine Poskin
Jan Van Schoor
Kris Denhaerynck
Stefaan Vancayzeele
Ivo Abraham
et al.
A1
Journal Article
in
ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY
2019
2018
A genome-wide linkage study for chronic obstructive pulmonary disease in a Dutch genetic isolate identifies novel rare candidate variants
Ivana Nedeljkovic
Natalie Terzikhan
Judith M Vonk
Diana A van der Plaat
Lies Lahousse
Cleo C van Diemen
Brian D Hobbs
Dandi Qiao
Michael H Cho
Guy Brusselle
et al.
A1
Journal Article
in
FRONTIERS IN GENETICS
2018
A prospective, longitudinal study evaluating the baseline six-minute walk test as an individual reference value in systemic sclerosis patients
Els Vandecasteele
Karin Melsens
Filip De Keyser
Michel De Pauw
Ellen Deschepper
Saskia Decuman
Yves Piette
Kristof Thevissen
Guy Brusselle
Vanessa Smith
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
2018
After asthma : redefining airways diseases
Ian D Pavord
Richard Beasley
Alvar Agusti
Gary P Anderson
Elisabeth Bel
Guy Brusselle
Paul Cullinan
Adnan Custovic
Francine M Ducharme
John V Fahy
et al.
A1
Journal Article
in
LANCET
2018
Anti-MDA5 positive dermatomyositis complicated with rapidly progressive interstitial lung disease : a case report
Eva De Backer
Félix Gremonprez
Guy Brusselle
Pieter Depuydt
Jo Van Dorpe
Carole Van Haverbeke
Pieter Goeminne
Eric Derom
A1
Journal Article
in
ACTA CLINICA BELGICA
2018
Association between blood eosinophil count and risk of readmission for patients with asthma : historical cohort study
Marjan Kerkhof
Trung N Tran
Maarten van den Berge
Guy Brusselle
Gokul Gopalan
Rupert CM Jones
Janwillem WH Kocks
Andrew Menzies-Gow
Javier Nuevo
Ian D Pavord
et al.
A1
Journal Article
in
PLOS ONE
2018
Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD
Elise De Smet
Leen Seys
Fien Verhamme
Bart M Vanaudenaerde
Guy Brusselle
Colin D Bingle
Ken Bracke
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
2018
Asthma and its comorbidities in middle-aged and older adults : the Rotterdam study
Emmely de Roos
Lies Lahousse
Katia Verhamme
Gert-Jan Braunstahl
M Arfan Ikram
Johannes CCM in't Veen
Bruno HCh Stricker
Guy Brusselle
A1
Journal Article
in
RESPIRATORY MEDICINE
2018
Blood eosinophil levels as a biomarker in COPD
Guy Brusselle
Ian D Pavord
Sarah Landis
Steven Pascoe
Sally Lettis
Nikhil Morjaria
Neil Barnes
Emma Hilton
A1
Journal Article
in
RESPIRATORY MEDICINE
2018
COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression
Ivana Nedeljkovic
Lies Lahousse
Elena Carnero-Montoro
Alen Faiz
Judith M Vonk
Kim de Jong
Diana A van der Plaat
Cleo C van Diemen
Maarten van den Berge
Ma'en Obeidat
et al.
A1
Journal Article
in
HUMAN MOLECULAR GENETICS
2018
COPD is associated with an increased risk of peripheral artery disease and mortality
Natalie Terzikhan
Lies Lahousse
Katia Verhamme
Oscar H Franco
Arfan M Ikram
Bruno H Stricker
Guy Brusselle
A2
Journal Article
in
ERJ OPEN RESEARCH
2018
DPP4, the Middle East respiratory syndrome coronavirus receptor, is upregulated in lungs of smokers and chronic obstructive pulmonary disease patients
Leen Seys
W Widagdo
Fien Verhamme
Alex Kleinjan
Wim Janssens
Guy Joos
Ken Bracke
Bart L Haagmans
Guy Brusselle
A1
Journal Article
in
CLINICAL INFECTIOUS DISEASES
2018
Dupilumab in patients with corticosteroid-dependent severe asthma : efficacy and safety results from the randomized, double-blind, placebo-controlled phase 3 LIBERTY ASTHMA VENTURE study
KF Rabe
PK Nair
Guy Brusselle
JF Maspero
M Castro
H Zhu
H Staudinger
G Pirozzi
C Antoni
N. Amin
et al.
C3
Conference
2018
ERS clinical research collaborations : underpinning research excellence
Chris Brightling
Celine Genton
Werner Bill
Tobias Welte
Mina Gaga
Elise Heuvelin
Guy Brusselle
Editorial material
2018
Efficacy and safety of dupilumab in glucocorticoid-dependent severe asthma
Klaus F Rabe
Parameswaran Nair
Guy Brusselle
Jorge F Maspero
Mario Castro
Lawrence Sher
Hongjie Zhu
Jennifer D Hamilton
Brian N Swanson
Asif H. Khan
et al.
A1
Journal Article
in
NEW ENGLAND JOURNAL OF MEDICINE
2018
Genetic and non-genetic determinants and clinical consequences of impaired lung function
Natalie Terzikhan
Guy Brusselle
BH Stricker
Lies Lahousse
Katia Verhamme
Dissertation
2018
Heritability and genome-wide association study of diffusing capacity of the lung
Natalie Terzikhan
Fangui Sun
Fien Verhamme
Hieab HH Adams
Daan Loth
Ken Bracke
Bruno HC Stricker
Lies Lahousse
Josée Dupuis
Guy Brusselle
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2018
IL-33 signalling contributes to pollutant-induced allergic airway inflammation
Katrien De Grove
Sharen Provoost
Harald Braun
Evy Blomme
Andrea Renate Teufelberger
Olga Krysko
Rudi Beyaert
Guy Brusselle
Guy Joos
Tania Maes
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
2018
Influence of genetic variants on childhood lung function : the Generation R study
Sara S Shagiwal
Herman T den Dekker
Johan C de Jongste
Guy Brusselle
Vincent WV Jaddoe
Janine F Felix
Liesbeth Duijts
A1
Journal Article
in
PEDIATRIC ALLERGY AND IMMUNOLOGY
2018
Insights in particulate matter-induced allergic airway inflammation : focus on the epithelium
Katrien De Grove
Sharen Provoost
Guy Brusselle
Guy Joos
Tania Maes
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
2018
Measures of subclinical cardiac dysfunction and increased filling pressures associate with pulmonary arterial pressure in the general population : results from the population-based Rotterdam Study
Ryan J Billar
Maarten JG Leening
Daphne Merkus
Guy Brusselle
Albert Hofman
Bruno HCh Stricker
H Ardeschir Ghofrani
Oscar H Franco
Henning Gall
Janine F Felix
A1
Journal Article
in
EUROPEAN JOURNAL OF EPIDEMIOLOGY
2018
Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function
Jiayi Xu
Traci M Bartz
Geetha Chittoor
Gudny Eiriksdottir
Ani W Manichaikul
Fangui Sun
Natalie Terzikhan
Xia Zhou
Sarah L Booth
Guy Brusselle
et al.
A1
Journal Article
in
BRITISH JOURNAL OF NUTRITION
2018
Meta-analysis of exome array data identifies six novel genetic loci for lung function
VE Jackson
JC Latourelle
LV Wain
AV Smith
ML Grove
TM Bartz
M Obeidat
MA Province
W Gao
B Qaiser
et al.
A2
Journal Article
in
WELLCOME OPEN RESEARCH
2018
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
Florence Demenais
Patricia Margaritte-Jeannin
Kathleen C Barnes
William OC Cookson
Janine Altmueller
Wei Ang
R Graham Barr
Terri H Beaty
Allan B Becker
John Beilby
et al.
A1
Journal Article
in
NATURE GENETICS
2018
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function
Annah B Wyss
Tamar Sofer
Mi Kyeong Lee
Natalie Terzikhan
Jennifer N Nguyen
Lies Lahousse
Jeanne C Latourelle
Albert Vernon Smith
Traci M Bartz
Mary F Feitosa
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2018
New era for European Respiratory Society clinical practice guidelines : joining efficiency and high methodological standards
Marc Miravitlles
Thomy Tonia
David Rigau
Nicolas Roche
Celine Genton
Valerie Vaccaro
Tobias Welte
Mina Gaga
Guy Brusselle
Editorial material
2018
Performance of database-derived severe exacerbations and asthma control measures in asthma : responsiveness and predictive utility in a UK primary care database with linked questionnaire data
Gene Colice
Alison Chisholm
Alexandra L. Dima
Helen K. Reddel
Annie Burden
Richard J. Martin
Guy Brusselle
Todor A. Popov
Julie von Ziegenweidt
David B. Price
A2
Journal Article
in
PRAGMATIC AND OBSERVATIONAL RESEARCH
2018
Personalized medicine with biologics for severe type 2 asthma : current status and future prospects
Marie Godar
Christophe Blanchetot
Hans de Haard
Bart Lambrecht
Guy Brusselle
A1
Journal Article
in
MABS
2018
Physical activity and cause-specific mortality : the Rotterdam Study
Chantal M Koolhaas
Klodian Dhana
Josje D Schoufour
Lies Lahousse
Frank JA van Rooij
M Arfan Ikram
Guy Brusselle
Henning Tiemeier
Oscar H Franco
A1
Journal Article
in
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
2018
Sarcopenia and its clinical correlates in the general population : the Rotterdam study
Katerina Trajanoska
Josje D Schoufour
Sirwan KL Darweesh
Elizabeth Benz
Carolina Medina-Gomez
Louise JM Alferink
Lies Lahousse
Guy Brusselle
Bruno Stricker
Sarwa Darwish Murad
et al.
A1
Journal Article
in
JOURNAL OF BONE AND MINERAL RESEARCH
2018
Serum phosphate levels are related to all-cause, cardiovascular and COPD mortality in men
Natalia Campos-Obando
Lies Lahousse
Guy Brusselle
Bruno H Stricker
Albert Hofman
Oscar H Franco
André G Uitterlinden
M Carola Zillikens
A1
Journal Article
in
EUROPEAN JOURNAL OF EPIDEMIOLOGY
2018
The European Respiratory Society : ensuring excellence through education best practice
Amy Farr
Mina Gaga
Tobias Welte
Thierry Troosters
Guy Joos
Carlos Robalo Cordeiro
O Chris Burghuber
Guy Brusselle
Christina-Georgia Gratziou
Andrew Bush
et al.
Editorial material
2018
The European Respiratory Society's 10 principles for lung health
Ildiko Horvath
Maeve Barry
Guy Brusselle
Otto Chris Burghuber
Andrew Bush
Carlos Robalo Cordeiro
Mina Gaga
Christina Gratziou
Isabel Saraiva
Daiana Stolz
et al.
Editorial material
2018
The role of microRNA-155 in cigarette smoke-induced inflammation
Elise De Smet
Pieter Mestdagh
Francisco Avila Cobos
Evy Blomme
Fien Verhamme
Sharen Provoost
Tania Maes
Guy Joos
Guy Brusselle
Ken Bracke
C3
Conference
2018
The significance of eosinophilic inflammation in chronic obstructive pulmonary disease
Christopher B Cooper
Guy Brusselle
Steven J Pascoe
Ian D Pavord
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2018
Toward effective prescription of inhaled corticosteroids in chronic airway disease
Zuzana Diamant
Guy Brusselle
Richard E Russell
Editorial material
2018
Two years follow-up of an open-label pilot study of treatment with rituximab in patients with early diffuse cutaneous systemic sclerosis
Karin Melsens
Els Vandecasteele
Ellen Deschepper
Valérie Badot
Daniel Blockmans
Guy Brusselle
Ellen De Langhe
Michel De Pauw
Claire Debusschere
Saskia Decuman
et al.
A1
Journal Article
in
ACTA CLINICA BELGICA
2018
Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics
Ivana Nedeljkovic
Elena Carnero-Montoro
Lies Lahousse
Diana A van der Plaat
Kim de Jong
Judith M Vonk
Cleo C van Diemen
Alen Faiz
Maarten van den Berge
Ma'en Obeidat
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2018
Urgent need for pragmatic trial platforms in severe asthma
Charles Pilette
Chris Brightling
Denis Lacombe
Guy Brusselle
Editorial material
2018
2017
A genome-wide linkage study for COPD in a Dutch genetic isolate
Ivana Nedeljkovic
Natalie Terzikhan
Judith M Vonk
Diana A van der Plaat
Lies Lahousse
Cleo C van Diemen
Guy Brusselle
H Marike Boezen
Cornelia M van Duijn
Najaf Amin
C3
Conference
2017
Adherence to the 2015 Dutch dietary guidelines and risk of non-communicable diseases and mortality in the Rotterdam study
Trudy Voortman
Jessica C Kiefte-de Jong
M Arfan Ikram
Bruno H Stricker
Frank JA van Rooij
Lies Lahousse
Henning Tiemeier
Guy Brusselle
Oscar H Franco
Josje D Schoufour
A1
Journal Article
in
EUROPEAN JOURNAL OF EPIDEMIOLOGY
2017
Association between blood eosinophil count and exacerbation risk in patients with asthma receiving medium- or high-dosage inhaled corticosteroids
Marjan Kerkhof
Trung N Tran
Maarten van den Berge
Guy Brusselle
Gokul Gopalan
Rupert Jones
JanWillem Kocks
Andrew Menzies-Gow
Javier Nuevo
Ian Pavord
et al.
C3
Conference
2017
Association between blood eosinophil counts and risk of rehospitalization in patients with asthma
Marjan Kerkhof
Trung N Tran
Maarten van den Berge
Guy Brusselle
Gokul Gopalan
Rupert Jones
JanWillem Kocks
Andrew Menzies-Gow
Javier Nuevo
Ian Pavord
et al.
C3
Conference
2017
Association between lutein intake and lung function in adults : the Rotterdam Study
Debora Melo van Lent
Elisabeth TM Leermakers
Albert Hofman
Bruno H Stricker
Guy Brusselle
Oscar H Franco
Lies Lahousse
Jessica C Kiefte-de Jong
A1
Journal Article
in
BRITISH JOURNAL OF NUTRITION
2017
Azithromycin in uncontrolled asthma
Guy Brusselle
Ian Pavord
Editorial material
2017
Blood eosinophil count and exacerbation risk in patients with COPD
Marjan Kerkhof
Samatha Sonnappa
Dirkje S Postma
Guy Brusselle
Alvar Agusti
Antonio Anzueto
Rupert Jones
Alberto Papi
Ian Pavord
Emilio Pizzichini
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2017
Blood eosinophils and smoking history affect outcome with high dose N-acetylcysteine treatment in COPD
Alberto Papi
Guy Brusselle
Francesco Sergio
Marco Pannacci
Jinping Zheng
Gerard Criner
C3
Conference
2017
Care pathways for the selection of a biologic in severe asthma
Jean Bousquet
Guy Brusselle
Roland Buhl
William W Busse
Alvaro A Cruz
Ratko Djukanovic
Christian Domingo
Nicola A Hanania
Marc Humbert
Andrew Menzies Gow
et al.
Editorial material
2017
Comparing the use and onset of palliative care services in chronic obstructive pulmonary disease (COPD) and lung cancer : a population-based mortality follow-back survey
Charlotte Scheerens
Kim Beernaert
Guy Brusselle
J Cohen
Luc Deliens
Kenneth Chambaere
C3
Conference
2017
Design of a frailty index among community living middle-aged and older people : the Rotterdam study
Josje D Schoufour
Nicole S Erler
Loes Jaspers
Jessica C Kiefte-de Jong
Trudy Voortman
Gijsbertus Ziere
Jan Lindemans
Caroline C Klaver
Henning Tiemeier
Bruno Stricker
et al.
A1
Journal Article
in
MATURITAS
2017
Development of a healthy aging score in the population-based Rotterdam study : evaluating age and sex differences
Loes Jaspers
Josje D Schoufour
Nicole S Erler
Sirwan KL Darweesh
Marileen LP Portegies
Sanaz Sedaghat
Lies Lahousse
Guy Brusselle
Bruno H Stricker
Henning Tiemeier
et al.
A1
Journal Article
in
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
2017
Dietary mineral intake and lung cancer risk : the Rotterdam study
Taulant Muka
Bledar Kraja
Rikje Ruiter
Lies Lahousse
Catherine E De Keyser
Albert Hofman
Oscar H Franco
Guy Brusselle
Bruno H Stricker
Jessica C Kiefte-de Jong
A1
Journal Article
in
EUROPEAN JOURNAL OF NUTRITION
2017
Direct detection of circulating microRNAs unveiled the absence of microRNA-218-5p in smoker subjects : reply
Griet Conickx
Pieter Mestdagh
Jo Vandesompele
Guy Brusselle
Ken Bracke
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2017
Dysregulation of type 2 innate lymphoid cells and TH2 cells impairs pollutant-induced allergic airway responses
Katrien De Grove
Sharen Provoost
Rudi W Hendriks
Andrew NJ McKenzie
Leen Seys
Smitha Kumar
Tania Maes
Guy Brusselle
Guy Joos
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2017
Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure
Fien Verhamme
Leen Seys
Elise De Smet
Sharen Provoost
W Janssens
Dirk Elewaut
Guy Joos
Guy Brusselle
Ken Bracke
A1
Journal Article
in
MUCOSAL IMMUNOLOGY
2017
End-stage cystic fibrosis lung disease is characterised by a diverse inflammatory pattern : an immunohistochemical analysis
Elise J Lammertyn
Elly Vandermeulen
Hannelore Bellon
Stephanie Everaerts
Stijn E Verleden
Kathleen Van den Eynde
Ken Bracke
Guy Brusselle
Pieter C Goeminne
Erik K Verbeken
et al.
A1
Journal Article
in
RESPIRATORY RESEARCH
2017
Epidemiology and impact of chronic bronchitis in chronic obstructive pulmonary disease
Lies Lahousse
Leen Seys
Guy Joos
Oscar H Franco
Bruno H Stricker
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2017
Evaluation of the psychometric properties of the St George's Respiratory Questionnaire in patients with severe asthma
Linda M Nelsen
Margaret Vernon
Hector Ortega
Sarah M Cockle
Steven W Yancey
Guy Brusselle
Frank C Albers
Paul W Jones
A1
Journal Article
in
RESPIRATORY MEDICINE
2017
Evidence for large-scale gene-by-smoking interaction effects on pulmonary function
Hugues Aschard
Martin D Tobin
Dana B Hancock
David Skurnik
Akshay Sood
Alan James
Albert Vernon Smith
Aniw Manichaikul
Archie Campbell
Bram P Prins
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
2017
FeNO and blood eosinophils as biomarkers in predicting asthma exacerbations
S Rastogi
S Bosnic-Antievich
I Pavord
N Roche
D Halpin
L Bjermer
OS Usmani
Guy Brusselle
S Wan Yau Ming
S Halim
et al.
C3
Conference
2017
Genes and pathways underlying susceptibility to impaired lung function in the context of environmental tobacco smoke exposure
K de Jong
JM Vonk
M Imboden
Lies Lahousse
A Hofman
Guy Brusselle
NM Probst-Hensch
DS Postma
HM Boezen
A1
Journal Article
in
RESPIRATORY RESEARCH
2017
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis
Brian D Hobbs
Kim de Jong
Maxime Lamontagne
Yohan Bosse
Nick Shrine
Maria Soler Artigas
Louise V Wain
Ian P Hall
Victoria E Jackson
Annah B Wyss
et al.
A1
Journal Article
in
NATURE GENETICS
2017
Genome-wide association study on the FEV1/FVC ratio in never-smokers identifies HHIP and FAM13A
Diana A van der Plaat
Kim de Jong
Lies Lahousse
Alen Faiz
Judith M Vonk
Cleo C. van Diemen
Ivana Nedeljkovic
Najaf Amin
Guy Brusselle
Albert Hofman
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2017
Immunological diversity in phenotypes of chronic lung allograft dysfunction : a comprehensive immunohistochemical analysis
Elly Vandermeulen
Elise Lammertyn
Stijn E Verleden
David Ruttens
Hannelore Bellon
Mario Ricciardi
Jana Somers
Ken Bracke
Kathleen Van Den Eynde
Thomas Tousseyn
et al.
A1
Journal Article
in
TRANSPLANT INTERNATIONAL
2017
Improvement in rhinosinusitis health related quality of life in patients with severe eosinophilic asthma
Linda Nelsen
Eric S Bradford
Daniel J Bratton
Frank C Albers
Guy Brusselle
C3
Conference
2017
Increased levels of enzymes involved in local estradiol synthesis in chronic obstructive pulmonary disease
GFJ Konings
NL Reynaert
B Delvoux
Fien Verhamme
Ken Bracke
Guy Brusselle
A Romano
JHJ Vernooy
A1
Journal Article
in
MOLECULAR AND CELLULAR ENDOCRINOLOGY
2017
Increased risk of peripheral arterial disease in individuals with COPD
Natalie Terzikhan
Lies Lahousse
Katia Verhamme
Oscar Franco
Guy Brusselle
Bruno Stricker
C3
Conference
2017
Influence of chronic azithromycin treatment on the composition of the oropharyngeal microbial community in patients with severe asthma
Guido Lopes dos Santos Santiago
Guy Brusselle
Kenny Dauwe
Pieter Deschaght
Chris Verhofstede
Dries Vaneechoutte
Ellen Deschepper
Paul Jordens
Guy Joos
Mario Vaneechoutte
A1
Journal Article
in
BMC MICROBIOLOGY
2017
MicroRNA profiling reveals a role for microRNA-218-5p in the pathogenesis of chronic obstructive pulmonary disease
Griet Conickx
Pieter Mestdagh
Francisco Avila Cobos
Fien Verhamme
Tania Maes
Bart M Vanaudenaerde
Leen Seys
Lies Lahousse
Richard Y Kim
Alan C Hsu
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2017
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD
Hoeke A Baarsma
Wioletta Skronska-Wasek
Kathrin Mutze
Florian Ciolek
Darcy E Wagner
Gerrit John-Schuster
Katharina Heinzelmann
Andreas Günther
Ken Bracke
Maylis Dagouassat
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2017
Peripheral artery disease in patients with chronic obstructive pulmonary disease
Guy Brusselle
Ken Bracke
Michel De Pauw
Editorial material
2017
Prevalence and incidence of pulmonary arterial hypertension : 10-year follow-up of an unselected systemic sclerosis cohort
Els Vandecasteele
Karin Melsens
Kristof Thevissen
Michel De Pauw
Ellen Deschepper
Saskia Decuman
Yves Piette
Filip De Keyser
Guy Brusselle
Vanessa Smith
A2
Journal Article
in
JOURNAL OF SCLERODERMA AND RELATED DISORDERS
2017
Prevalence of hypertension among elderly asthmatics : the Rotterdam Study
Emmely De Roos
Lies Lahousse
Arfan Ikram
Bruno Stricker
Guy Brusselle
Katia Verhamme
C3
Conference
2017
Pulmonary artery to aorta ratio and risk of all-cause mortality in the general population : the Rotterdam Study
Natalie Terzikhan
Daniel Bos
Lies Lahousse
Lennard Wolff
Katia MC Verhamme
Maarten JG Leening
Janine F Felix
Henning Gall
Hossein A Ghofrani
Oscar H Franco
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2017
Pulmonary function and diffusion capacity are associated with pulmonary arterial systolic pressure in the general population : the Rotterdam study
Daan W Loth
Lies Lahousse
Maarten JG Leening
Bouwe P Krijthe
Janine F Felix
Henning Gall
Albert Hofman
H Ardeschir Ghofrani
Oscar H Franco
Bruno H Stricker
et al.
A1
Journal Article
in
RESPIRATORY MEDICINE
2017
Qualitative evaluation of the St George's Respiratory Questionnaire in patients with severe asthma
Linda M Nelsen
Miriam Kimel
Lindsey T Murray
Hector Ortega
Sarah M Cockle
Steven W Yancey
Guy Brusselle
Frank C Albers
Paul W Jones
A1
Journal Article
in
RESPIRATORY MEDICINE
2017
Reduced frizzled receptor 4 expression prevents WNT/β-catenin-driven alveolar lung repair in chronic obstructive pulmonary disease
Wioletta Skronska-Wasek
Kathrin Mutze
Hoeke A Baarsma
Ken Bracke
Hani N Alsafadi
Mareike Lehmann
Rita Costa
Mariano Stornaiuolo
Ettore Novellino
Guy Brusselle
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2017
Reslizumab in eosinophilic asthma : a review
Emma D Deeks
Guy Brusselle
A1
Journal Article
in
DRUGS
2017
Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils
Guy Brusselle
Matthew Germinaro
Sivan Weiss
James Zangrilli
A1
Journal Article
in
PULMONARY PHARMACOLOGY & THERAPEUTICS
2017
Role of microRNAs in the pathogenesis of chronic obstructive pulmonary disease (COPD)
Griet Conickx
Guy Brusselle
Ken Bracke
Dissertation
2017
Role of the six-minute walk test in systemic sclerosis : five years evolution
Els Vandecasteele
Karin Melsens
Filip De Keyser
Michel De Pauw
Ellen Deschepper
Saskia Decuman
Yves Piette
Kristof Thevissen
Guy Brusselle
Vanessa Smith
C3
Conference
2017
Screening for pulmonary arterial hypertension in an unselected prospective systemic sclerosis cohort
Els Vandecasteele
BENNY DRIEGHE
Karin Melsens
Kristof Thevissen
Michel De Pauw
Ellen Deschepper
Saskia Decuman
Carolien Bonroy
Yves Piette
Filip De Keyser
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2017
Sex-differences in mortality within the COPD chronic bronchitis phenotype
Lies Lahousse
Leen Seys
Guy Joos
Oscar Franco
Bruno Stricker
Guy Brusselle
C3
Conference
2017
Sex-specific genetic risk factors for chronic obstructive pulmonary disease
Guy Brusselle
Lies Lahousse
Editorial material
2017
Six-minute walk test in or out in evaluation of systemic sclerosis patients?
Els Vandecasteele
Kristof Thevissen
Karin Melsens
Filip De Keyser
Michel De Pauw
Ellen Deschepper
Saskia Decuman
Yves Piette
Guy Brusselle
Vanessa Smith
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
2017
Sputum neutrophil elastase as a biomarker for disease activity in bronchiectasis
Guy Brusselle
Eva Van Braeckel
Editorial material
2017
Stratification of eosinophilic asthma patients treated with reslizumab and GINA Step 4 or 5 therapy
Guy Brusselle
Janice Canvin
Sivan Weiss
Shawn X Sun
Roland Buhl
A2
Journal Article
in
ERJ OPEN RESEARCH
2017
Systeemsclerose
Els Vandecasteele
Michel De Pauw
Eric Derom
Guy Brusselle
Sofie De Schepper
Filip De Keyser
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2017
Taken to task : what is and is not an appropriate response to an ERS guidelines task force?
Guy Joos
Andrew Bush
Otto Chris Burghuber
Carlos Robalo Cordeiro
Mina Gaga
G John Gibson
Christina Gratziou
David Rigau
Gernot Rohde
Dan Smyth
et al.
Editorial material
2017
The Rotterdam study : 2018 update on objectives, design and main results
M Arfan Ikram
Guy Brusselle
Sarwa Darwish Murad
Cornelia M van Duijn
Oscar H Franco
Andr Goedegebure
Caroline CW Klaver
Tamar EC Nijsten
Robin P Peeters
Bruno H Stricker
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF EPIDEMIOLOGY
2017
The role of dicer in alveolar macrophages and dendritic cells in smoke-induced inflammation
Elise De Smet
Pieter Mestdagh
S Provoost
Leen Seys
Guy Joos
Karim Vermaelen
Guy Brusselle
Ken Bracke
C3
Conference
2017
microRNA profiling in lung tissue and bronchoalveolar lavage of cigarette smoke-exposed mice and in COPD patients : a translational approach
Griet Conickx
Francisco Avila Cobos
Maarten van den Berge
Alen Faiz
Wim Timens
Pieter S. Hiemstra
Guy Joos
Guy Brusselle
Pieter Mestdagh
Ken Bracke
A1
Journal Article
in
SCIENTIFIC REPORTS
2017
2016
A qualitative interpretation of challenges associated with helping patients with multiple chronic diseases identify their goals
Pauline Boeckxstaens
Sara Willems
Mieke Lanssens
Charlotte Decuypere
Guy Brusselle
Thomas Kühlein
Jan De Maeseneer
An De Sutter
A2
Journal Article
in
JOURNAL OF COMORBIDITY
2016
AZALEA trial highlights antibiotic overuse in acute asthma attacks
Guy Brusselle
Eva Van Braeckel
Editorial material
2016
Aggravation of allergic airway inflammation by cigarette smoke in mice is CD44-dependent
Smitha Kumar
Ellen Lanckacker
Mieke Dentener
Ken Bracke
Sharen Provoost
Katrien De Grove
Guy Brusselle
Emiel Wouters
Tania Maes
Guy Joos
A1
Journal Article
in
PLOS ONE
2016
Assessment of sensitivity to change of the European Scleroderma Study Group activity index
Karin Melsens
Filip De Keyser
Saskia Decuman
Guy Brusselle
Michel De Pauw
Ellen Deschepper
Katelijne De Wilde
Dirk Elewaut
YVES PIETTE
Els Vandecasteele
et al.
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
2016
Asthma inflammatory phenotypes show differential microRNA expression in sputum
Tania Maes
Francisco Avila Cobos
Florence Schleich
Valentina Sorbello
Monique Henket
Katleen De Preter
Ken Bracke
Griet Conickx
Claire Mesnil
Jo Vandesompele
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2016
Cardiac effects of current treatments of chronic obstructive pulmonary disease
Lies Lahousse
Katia Verhamme
Bruno H Stricker
Guy Brusselle
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2016
Changes in initial COPD treatment choice over time and factors influencing prescribing decisions in UK primary care : in UK primary care: a real-world, retrospective, observational
Kevin Gruffydd-Jones
Guy Brusselle
Rupert Jones
Marc Miravitlles
Michael Baldwin
Rebecca Stewart
Anna Rigazio
Emily Davis
Dorothy L Keininger
David Price
A1
Journal Article
in
NPJ PRIMARY CARE RESPIRATORY MEDICINE
2016
Characterization and quantification of innate lymphoid cell subsets in human lung
Katrien De Grove
Sharen Provoost
Fien Verhamme
Ken Bracke
Guy Joos
Tania Maes
Guy Brusselle
A1
Journal Article
in
PLOS ONE
2016
Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut
Liesbeth Allais
Frederiek-Maarten Kerckhof
Stephanie Verscheure
Ken Bracke
Rebecca De Smet
Debby Laukens
Pieter Van den Abbeele
Martine De Vos
Nico Boon
Guy Brusselle
et al.
A1
Journal Article
in
ENVIRONMENTAL MICROBIOLOGY
2016
Chronic obstructive pulmonary disease and sudden cardiac death: a systematic review
Marten E van den Berg
Bruno H Stricker
Guy Brusselle
Lies Lahousse
A1
Journal Article
in
TRENDS IN CARDIOVASCULAR MEDICINE
2016
Chronic obstructive pulmonary disease and the risk of stroke: the Rotterdam study
Marileen L Portegies
Lies Lahousse
Guy Joos
Albert Hofman
Peter J Koustaal
Bruno H Stricker
Guy Brusselle
M Arfan Ikram
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2016
Cigarette smoking and inflammatory bowel disease : insights into microbial and immune homeostasis
Liesbeth Allais
Claude Cuvelier
Guy Brusselle
Dissertation
2016
Determinants and impact of suboptimal asthma control in Europe: the INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study
Fulvio Braido
Guy Brusselle
Daniele Guastalla
Eleonora Ingrassia
Gabriele Nicolini
David Price
Nicolas Roche
Joan B Soriano
Heinrich Worth
A1
Journal Article
in
RESPIRATORY RESEARCH
2016
Efficacy of tiotropium-olodaterol fixed-dose combination in COPD
Eric Derom
Guy Brusselle
Guy Joos
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
2016
Epidemiology of chronic bronchitis in chronic obstructive pulmonary disease (COPD)
Leen Seys
Lies Lahousse
Guy Joos
A Hofman
B Stricker
Guy Brusselle
C3
Conference
2016
LncRNAs in the context of Chronic Obstructive Pulmonary Disease (COPD) are associated to immune response and metabolism of xenobiotics
Francisco Avila Cobos
Ken Bracke
Jo Vandesompele
Kimberly Verniers
Guy Joos
Katleen De Preter
Guy Brusselle
Pieter Mestdagh
C3
Conference
2016
Lung function abnormalities in smokers with ischemic heart disease
Frits ME Franssen
Joan B Soriano
Nicolas Roche
Paul H Bloomfield
Guy Brusselle
Leonardo M Fabbri
Francisco García-Rio
Mark T Kearney
Namhee Kwon
Bo Lundbäck
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2016
Meta-analysis of the association of serum vitamin D with pulmonary function
J Xu
TM Bartz
G Chittoor
G Eiriksdottir
AC Frazier-Wood
Lies Lahousse
J Latourelle
AW Manichaikul
F Sun
Natalie Terzikhan
et al.
C3
Conference
2016
Microrna-218-5p is implicated in the pathogenesis of chronic obstructive pulmonary disease
Griet Conickx
Pieter Mestdagh
Francisco Avila Cobos
Fien Verhamme
Tania Maes
BM Vanaudenaerde
Lies Lahousse
Guy Joos
Jo Vandesompele
Ken Bracke
et al.
C3
Conference
2016
Mucosal immunity in COPD : from mucociliary dysfunction to lymphoid follicles
Leen Seys
Guy Brusselle
Ken Bracke
Dissertation
2016
Prevalence and incidence of COPD in smokers and non-smokers: the Rotterdam study
Natalie Terzikhan
Katia MC Verhamme
Albert Hofman
Bruno H Stricker
Guy Brusselle
Lies Lahousse
A1
Journal Article
in
EUROPEAN JOURNAL OF EPIDEMIOLOGY
2016
Pro- and anti-inflammatory role of ChemR23 signaling in pollutant-induced inflammatory lung responses
Sharen Provoost
Katrien De Grove
Graeme L Fraser
Vincent J Lannoy
Kurt Tournoy
Guy Brusselle
Tania Maes
Guy Joos
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2016
Prostaglandin D₂ receptor antagonism: a novel therapeutic option for eosinophilic asthma?
Guy Brusselle
Sharen Provoost
Tania Maes
Editorial material
2016
Risk of frailty in elderly with COPD : a population-based study
Lies Lahousse
Gijsbertus Ziere
Vincentius JA Verlinden
M Carola Zillikens
André G Uitterlinden
Fernando Rivadeneira
Henning Tiemeier
Guy Joos
Albert Hofman
M Arfan Ikram
et al.
A1
Journal Article
in
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
2016
Rol van microRNA in neutrofiel astma
Tania Maes
Francisco Avila Cobos
Florence Schleich
Valentina Sorbello
Monique Henket
Katleen De Preter
Ken Bracke
Griet Conickx
Claire Mesnil
Jo Vandesompele
et al.
A4
Journal Article
in
BLOEDVATEN HART LONGEN
2016
Screening for pulmonary arterial hypertension in an unselected prospective systemic sclerosis cohort : the DETECT algorithm vs. the 2009 European Society of Cardiology/European Respiratory Society guidellines on pulmonary hypertension
Els Vandecasteele
BENNY DRIEGHE
Karin Melsens
Kristof Thevissen
Michel De Pauw
Ellen Deschepper
Saskia Decuman
Filip De Keyser
Carolien Bonroy
Yves Piette
et al.
C3
Conference
2016
Serum phosphate is related to all-cause, cardiovascular and COPD mortality in men: the Rotterdam study
MC Zillikens
N Campos-Obando
Lies Lahousse
Guy Brusselle
BH Stricker
OH Franco
AG Uitterlinden
C3
Conference
2016
Six-minute walk test in systemic sclerosis : a systematic review and meta-analysis
Els Vandecasteele
Michel De Pauw
Filip De Keyser
Saskia Decuman
Ellen Deschepper
YVES PIETTE
Guy Brusselle
Vanessa Smith
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CARDIOLOGY
2016
Six-minute walk test in systemic sclerosis patients
Els Vandecasteele
Karin Melsens
Filip De Keyser
Michel De Pauw
Ellen Deschepper
Saskia Decuman
YVES PIETTE
Guy Brusselle
Vanessa Smith
C3
Conference
2016
Six-minute walk test in systemic sclerosis patients without interstitial lung disease and pulmonary arterial hypertension
Els Vandecasteele
Karin Melsens
Filip De Keyser
Michel De Pauw
Ellen Deschepper
Saskia Decuman
YVES PIETTE
Guy Brusselle
Vanessa Smith
C3
Conference
2016
Stabilization of microcirculation in patients with early systemic sclerosis with diffuse skin involvement following rituximab treatment: an open-label study
Vanessa Smith
Carmen Pizzorni
Valeria Riccieri
Saskia Decuman
Guy Brusselle
Michel De Pauw
Ellen Deschepper
YVES PIETTE
Barbara Ruaro
Alberto Sulli
et al.
A1
Journal Article
in
JOURNAL OF RHEUMATOLOGY
2016
Targeted therapy for older patients with uncontrolled severe asthma: current and future prospects
Emmely de Roos
JCCM in 't Veen
G-J Braunstahl
Lies Lahousse
Guy Brusselle
A1
Journal Article
in
DRUGS & AGING
2016
The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial
Kristina Vermeersch
Maria Gabrovska
Griet Deslypere
Ingel K Demedts
Hans Slabbynck
Joseph Aumann
Vincent Ninane
Geert M Verleden
Thierry Troosters
Kris Bogaerts
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
2016
The European Respiratory Society evaluates its 2013-2018 strategic plan implementation
Giovanni Battista Migliori
Elisabeth Bel
Guy Joos
Mark Elliott
Gernot Rohde
Stephen T Holgate
Christina Gratziou
Dan Smyth
Mina Gaga
Carlos Robeiro Cordeiro
et al.
Editorial material
2016
The effects of lutein on respiratory health across the life course : a systematic review
Debora Melo van Lent
Elisabeth T. M. Leermakers
Sirwan K. L. Darweesh
Eduardo M. Moreira
Myrte J. Tielemans
Taulant Muka
Anna Vitezova
Rajiv Chowdhury
Wichor M. Bramer
Guy Brusselle
et al.
A2
Journal Article
in
CLINICAL NUTRITION ESPEN
2016
The ever-expanding ERS fellowship programmes : achievements over the past 3 years
Maria G Belvisi
Rory E Morty
Gernot Rohde
Marc Mriavitlles
Kathryn A Forrest
Céline Genton
Nathalie Ritter
Nikoleta Luludi
Albert Jimenez
David Rigau
et al.
Editorial material
2016
The evolving role of the community pharmacist : focus on medication screening in older patients with polypharmacy and medication counselling for patients with chronic obstructive pulmonary disease
Eline Tommelein
Koen Boussery
Mirko Petrovic
Guy Brusselle
Dissertation
2016
The heart and pulmonary arterial hypertension in systemic sclerosis
Els Vandecasteele
Michel De Pauw
Guy Brusselle
Saskia Decuman
Yves Piette
Filip De Keyser
Vanessa Smith
A1
Journal Article
in
ACTA CLINICA BELGICA
2016
Treatable traits : toward precision medicine of chronic airway diseases
Alvar Agusti
Elisabeth Bel
Mike Thomas
Claus Vogelmeier
Guy Brusselle
Stephen Holgate
Marc Humbert
Paul Jones
Peter G Gibson
Jørgen Vestbo
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2016
Understanding age-related diseases : report of the 2015 Ageing Summit
Lies Lahousse
Emmanuel Moyse
Slavica Krantic
Guy Brusselle
Editorial material
2016
Using a bronchial airway gene expression classifier
Karim Vermaelen
Guy Brusselle
Biography
2016
Vilanterol fluticasone and mortality in comorbid COPD GOLD B
Guy Brusselle
Editorial material
2016
2015
Airway surface dehydration aggravates cigarette smoke-induced hallmarks of COPD in mice
Leen Seys
Fien Verhamme
Lisa Dupont
Elke Desauter
Julia Duerr
Ayca Seyhan Agircan
Griet Conickx
Guy Joos
Guy Brusselle
Marcus A Mall
et al.
A1
Journal Article
in
PLOS ONE
2015
Are the antimicrobial properties of macrolides required for their therapeutic efficacy in chronic neutrophilic airway diseases?
Guy Brusselle
Editorial material
2015
Chronic obstructive pulmonary disease and cerebrovascular disease: a comprehensive review
Lies Lahousse
Henning Tiemeier
M Arfan Ikram
Guy Brusselle
A1
Journal Article
in
RESPIRATORY MEDICINE
2015
Chronic obstructive pulmonary disease and sudden cardiac death: the Rotterdam study
Lies Lahousse
Maartje N Niemeijer
Marten E van den Berg
Peter R Rijnbeek
Guy Joos
Albert Hofman
Oscar H Franco
Jaap W Deckers
Mark Eijgelsheim
Bruno H Stricker
et al.
A1
Journal Article
in
EUROPEAN HEART JOURNAL
2015
Dysregulated fibulin-5 expression and elastogenesis in COPD lungs: pyromaniac or fire fighter?
Guy Brusselle
Editorial material
2015
ERS guidelines, statements and technical standards published in the ERJ in 2014: a year in review
Guy Brusselle
Mina Gaga
Editorial material
2015
Elucidating COPD pathogenesis by large-scale genetic analyses
Guy Brusselle
Ken Bracke
Editorial material
2015
Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers : implications for autoimmunity in rheumatoid arthritis
Elena B Lugli
Raquel ESM Correia
Roman Fischer
Karin Lundberg
Ken Bracke
Anna B Montgomery
Benedikt M Kessler
Guy Brusselle
Patrick J Venables
A1
Journal Article
in
ARTHRITIS RESEARCH & THERAPY
2015
Gait patterns in COPD : the Rotterdam Study
Lies Lahousse
Vincentius JA Verlinden
Jos N van der Geest
Guy Joos
Albert Hofman
Bruno HC Stricker
Guy Brusselle
M Arfan Ikram
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2015
Identification of differentially expressed microRNAs in neutrophilic asthma
Tania Maes
Katleen De Preter
FN Schleich
M Henket
Ken Bracke
Lies Lahousse
Pieter Mestdagh
Guy Joos
Guy Brusselle
R Louis
C3
Conference
2015
MicroRNA miR-22 drives TH17 responses in emphysema
Guy Brusselle
Ken Bracke
Editorial material
2015
Molecular mechanisms underlying variations in lung function: a systems genetics analysis
Ma'en Obeidat
Ke Hao
Yohan Bossé
David C Nickle
Yunlong Nie
Dirkje S Postma
Michel Laviolette
Andrew J Sandford
Denise D Daley
James C Hogg
et al.
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2015
Non-coding RNAs and respiratory disease
Pieter Mestdagh
Jo Vandesompele
Guy Brusselle
Karim Vermaelen
A1
Journal Article
in
THORAX
2015
Non-coding RNAs in the pathogenesis of COPD
Elise De Smet
Pieter Mestdagh
Jo Vandesompele
Guy Brusselle
Ken Bracke
A1
Journal Article
in
THORAX
2015
Prevalence of pulmonary hypertension in the general population : the Rotterdam study
Eduardo M Moreira
Henning Gall
Maarten JG Leening
Lies Lahousse
Daan W Loth
Bouwe P Krijthe
Jessica C Kiefte-de Jong
Guy Brusselle
Albert Hofman
Bruno H Stricker
et al.
A1
Journal Article
in
PLOS ONE
2015
Real-world research and its importance in respiratory medicine
David Price
Guy Brusselle
Nicolas Roche
Daryl Freeman
Alison Chisholm
A2
Journal Article
in
BREATHE
2015
Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials
Mario Castro
James Zangrilli
Michael E Wechsler
Eric D Bateman
Guy Brusselle
Philip Bardin
Kevin Murphy
Jorge F Maspero
Christopher O'Brien
Stephanie Korn
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2015
Risk of a biased assessment of the evidence when limiting literature searches to the English language : macrolides in asthma as an illustrative example
Guy Brusselle
Francesco Blasi
Editorial material
2015
Role of B cell-activating factor in chronic obstructive pulmonary disease
Leen Seys
Fien Verhamme
Anja Schinwald
Hamida Hammad
Danen Mootoosamy Cunoosamy
Claudie Bantsimba-Malanda
Alan Sabirsh
Eileen McCall
Liz Flavell
Ronald Herbst
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2015
Role of lymphoid follicles and transforming growth factor (TGF)-β superfamily in the pathogenesis of chronic obstructive pulmonary disease (COPD)
Fien Verhamme
Guy Brusselle
Ken Bracke
Dissertation
2015
Six-minute walk test in systemic sclerosis : systematic review and meta-analysis
Els Vandecasteele
Michel De Pauw
Filip De Keyser
Saskia Decuman
Ellen Deschepper
YVES PIETTE
Guy Brusselle
Vanessa Smith
C3
Conference
2015
Targeted therapy with inhaled corticosteroids in COPD according to blood eosinophil counts
Guy Brusselle
Ken Bracke
Lies Lahousse
Editorial material
2015
The Rotterdam Study : 2016 objectives and design update
Albert Hofman
Guy Brusselle
Sarwa Darwish Murad
Cornelia M van Duijn
Oscar H Franco
André Goedegebure
M Arfan Ikram
Caroline CW Klaver
Tamar EC Nijsten
Robin P Peeters
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF EPIDEMIOLOGY
2015
The Rotterdam study : why fall in COPD?
Lies Lahousse
Vincentius JA Verlinden
M Arfan Ikram
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2015
The effect of cigarette smoke exposure on the development of inflammation in lungs, gut and joints of TNFΔARE mice
Liesbeth Allais
Smitha Kumar
Karlijn Debusschere
Stephanie VERSCHUERE
Tania Maes
Rebecca De Smet
Griet Conickx
Martine De Vos
Debby Laukens
Guy Joos
et al.
A1
Journal Article
in
PLOS ONE
2015
The inevitable drift to triple therapy in COPD: an analysis of prescribing pathways in the UK
Guy Brusselle
David Price
Kevin Gruffydd-Jones
Marc Miravitlles
Dorothy L Keininger
Rebecca Stewart
Michael Baldwin
Rupert C Jones
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
2015
Transforming growth factor-β superfamily in obstructive lung diseases: more suspects than TGF-β alone
Fien Verhamme
Ken Bracke
Guy Joos
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
2015
2014
A practice-based analysis of combinations of diseases in patients aged 65 or older in primary care
Pauline Boeckxstaens
Wim Peersman
Gwendolyn Goubin
Souhila Ghali
Jan De Maeseneer
Guy Brusselle
An De Sutter
A1
Journal Article
in
BMC FAMILY PRACTICE
2014
Accuracy of the Medication Adherence Report Scale (MARS-5) as a quantitative measure of adherence to inhalation medication in patients with COPD
Eline Tommelein
Els Mehuys
Inge Van Tongelen
Guy Brusselle
Koen Boussery
A1
Journal Article
in
ANNALS OF PHARMACOTHERAPY
2014
Adverse outcomes of frailty in the elderly: the Rotterdam study
Lies Lahousse
Bastiaan Maes
Gijsbertus Ziere
Daan W Loth
Vincentius JA Verlinden
M Carola Zillikens
André G Uitterlinden
Fernando Rivadeneira
Henning Tiemeier
Oscar H Franco
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF EPIDEMIOLOGY
2014
Bone mineral density and chronic lung disease mortality: the Rotterdam study
Natalia Campos-Obando
Martha C Castano-Betancourt
Ling Oei
Oscar H Franco
Bruno HCh Stricker
Guy Brusselle
Lies Lahousse
Albert Hofman
Henning Tiemeier
Fernando Rivadeneira
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
2014
Cause-specific mortality in mild COPD : the Rotterdam study
Lies Lahousse
Guy Joos
Albert Hofman
Bruno Stricker
Guy Brusselle
C3
Conference
2014
Cigarette smoke exposure alters the development of inflammation in experimental Crohn-like colitis
Liesbeth Allais
Stephanie Verscheure
Ken Bracke
Rebecca De Smet
Debby Laukens
Claus Bachert
Martine De Vos
Guy Brusselle
Claude Cuvelier
C3
Conference
2014
Common genes underlying asthma and COPD? : genome-wide analysis on the Dutch hypothesis
Joanna Smolonska
Gerard H Koppelman
Cisca Wijmenga
Judith M Vonk
Pieter Zanen
Marcel Bruinenberg
Ivan Curjuric
Medea Imboden
Gian-Andri Thun
Lude Franke
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2014
Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease
Maria Sabater-Lleal
Aners Mälarstig
Lasse Folkersen
María Soler Artigas
Damiano Baldassarre
Maryam Kavousi
Peter Almgren
Fabrizio Veglia
Guy Brusselle
Albert Hofman
et al.
A1
Journal Article
in
PLOS ONE
2014
De doeltreffendheid van farmaceutische zorg bij patiënten met COPD: bespreking van de recent gepubliceerde PHARMACOP-studie
Eline Tommelein
Els Mehuys
T Van Hees
Els Adriaens
Lucas Van Bortel
Thierry Christiaens
Inge Van Tongelen
Jean Paul Remon
Koen Boussery
Guy Brusselle
A4
Journal Article
in
FARMACEUTISCH TIJDSCHRIFT VOOR BELGIE [1971]
2014
Early origins of chronic obstructive lung diseases across the life course
Liesbeth Duijts
Irwin K Reiss
Guy Brusselle
Johan C de Jongste
A1
Journal Article
in
EUROPEAN JOURNAL OF EPIDEMIOLOGY
2014
Een 75-jarige vrouw met inspanningsgebonden kortademigheid en desaturatie
Maarten De Smet
Eline Naert
Thomas Malfait
Guy Brusselle
Eric Derom
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2014
Effectiveness of pharmaceutical care for patients with chronic obstructive pulmonary disease ( PHARMACOP): a randomized controlled trial
Eline Tommelein
Els Mehuys
Thierry Van Hees
Els Adriaens
Lucas Van Bortel
Thierry Christiaens
Inge Van Tongelen
Jean Paul Remon
Koen Boussery
Guy Brusselle
A1
Journal Article
in
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
2014
Epidemiology of comorbidities in chronic obstructive pulmonary disease
Lies Lahousse
Guy Brusselle
BH Stricker
Dissertation
2014
Frequent exacerbators: a distinct phenotype of severe asthma
M Kupczyk
A ten Brinke
PJ Sterk
EH Bel
A Papi
P Chanez
E Nizankowska-Mogilnicka
M Gjomarkaj
M Gaga
Guy Brusselle
et al.
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
2014
Genome-wide association analysis identifies six new loci associated with forced vital capacity
Daan W Loth
Maria Soler Artigas
Sina A Gharib
Louise V Wain
Nora Franceschini
Beate Koch
Tess D Pottinger
Albert Vernon Smith
Qing Duan
Chris Oldmeadow
et al.
A1
Journal Article
in
NATURE GENETICS
2014
Het optimaliseren van de farmacotherapie bij patiënten met chronisch obstructief longlijden (COPD) in de officina-apotheek: een kosten-effectiviteitsanalyse
JFM van Boven
Eline Tommelein
Koen Boussery
Els Mehuys
S Vegter
Guy Brusselle
MPMH Rutten-van Mölken
MJ Postma
A4
Journal Article
in
FARMACEUTISCH TIJDSCHRIFT VOOR BELGIE [1971]
2014
Heterogeneity of phenotypes in severe asthmatics: the Belgian Severe Asthma Registry (BSAR)
F Schleich
Guy Brusselle
R Louis
O Vandenplas
A Michils
C Pilette
R Peche
M Manise
Guy Joos
A1
Journal Article
in
RESPIRATORY MEDICINE
2014
Improving inhaler adherence in patients with Chronic Obstructive Pulmonary Disease : a cost-effectiveness analysis
Job FM van Boven
Eline Tommelein
Koen Boussery
Els Mehuys
Stefan Vegter
Guy Brusselle
Maureen PMH Rutten-van Mölken
Maarten J Postma
A1
Journal Article
in
RESPIRATORY RESEARCH
2014
Inflammasomes in respiratory disease: from bench to bedside
Guy Brusselle
Sharen Provoost
Ken Bracke
Anna Kuchmiy
Mohamed Lamkanfi
A1
Journal Article
in
CHEST
2014
Investigation of 5-HT4 receptors in bronchial hyperresponsiveness in cigarette smoke-exposed mice
Lisa Dupont
Ken Bracke
Joris H De Maeyer
Valérie Compan
Guy Joos
Romain Lefebvre
Guy Brusselle
A1
Journal Article
in
PULMONARY PHARMACOLOGY & THERAPEUTICS
2014
Is there a role for macrolides in severe asthma?
Guy Brusselle
Guy Joos
A1
Journal Article
in
CURRENT OPINION IN PULMONARY MEDICINE
2014
Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function
Wenbo Tang
Matthew Kowgier
Daan W Loth
María Soler Artigas
Bonnie R Joubert
Emily Hodge
Sina A Gharib
Albert V Smith
Ingo Ruczinski
Vilmundur Gudnason
et al.
A1
Journal Article
in
PLOS ONE
2014
Management of COPD in the UK primary-care setting: an analysis of real-life prescribing patterns
David Price
Daniel West
Guy Brusselle
Kevin Gruffydd-Jones
Rupert Jones
Marc Miravitlles
Andrea Rossi
Catherine Hutton
Valerie L Ashton
Rebecca Stewart
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
2014
Mechanistic links between COPD and lung cancer: a role of microRNA let-7?
Jae Il Shin
Guy Brusselle
A1
Journal Article
in
NATURE REVIEWS CANCER
2014
Mepolizumab treatment in patients with severe eosinophilic asthma
Hector G Ortega
Mark C Liu
Ian D Pavord
Guy Brusselle
J Mark FitzGerald
Alfredo Chetta
Marc Humbert
Lynn E Katz
Oliver N Keene
Steven W Yancey
et al.
A1
Journal Article
in
NEW ENGLAND JOURNAL OF MEDICINE
2014
Multimorbidity : a quantitative and qualitative exploration in primary care
Pauline Boeckxstaens
An De Sutter
Guy Brusselle
Jean-Marie Degryse
Dissertation
2014
Opportunities to diagnose chronic obstructive pulmonary disease in routine care in the UK: a retrospective study of a clinical cohort
Rupert CM Jones
David Price
Dermot Ryan
Erika J Sims
Julie von Ziegenweidt
Laurence Mascarenhas
Anne Burden
David MG Halpin
Robert Winter
Sue Hill
et al.
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2014
Optimalisation de la pharmacothérapie en pharmacie d'officine chez des patients atteints de Bronchopneumopathie Chronique Obstructive (BPCO): une analyse coût-efficacité
JFM van Boven
Eline Tommelein
Koen Boussery
Els Mehuys
S Vegter
Guy Brusselle
MPMH Rutten-van Mölken
MJ Postma
A4
Journal Article
in
JOURNAL DE PHARMACIE DE BELGIQUE
2014
Quality standards for real-world research: focus on observational database studies of comparative effectiveness
Nicolas Roche
Helen Reddel
Richard Martin
Guy Brusselle
Alberto Papi
Mike Thomas
Dirjke Postma
Vicky Thomas
Cynthia Rand
Alison Chisholm
et al.
A2
Journal Article
in
ANNALS OF THE AMERICAN THORACIC SOCIETY
2014
Role of Transient Receptor Potential Channel A1, serotonin receptor 5-HT4R and soluble guanylyl cyclase in the pathogenesis of chronic obstructive pulmonary disease
Lisa Dupont
Guy Brusselle
Guy Joos
Dissertation
2014
Role of activin-A in cigarette smoke-induced inflammation and COPD
Fien Verhamme
Ken Bracke
Gimano D Amatngalim
Geert M Verleden
Geert Van Pottelberge
Pieter S Hiemstra
Guy Joos
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2014
Role of the nitric oxide-soluble guanylyl cyclase pathway in obstructive airway diseases
Lisa Dupont
Constantinos Glynos
Ken Bracke
Peter Brouckaert
Guy Brusselle
A1
Journal Article
in
PULMONARY PHARMACOLOGY & THERAPEUTICS
2014
Self-medication in persistent rhinitis: overuse of decongestants in half of the patients
Els Mehuys
Philippe Gevaert
Guy Brusselle
Thierry Van Hees
Els Adriaens
Thierry Christiaens
Lucas Van Bortel
Inge Van Tongelen
Jean Paul Remon
Koen Boussery
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY IN PRACTICE
2014
Self-medication in persistent rhinitis: overuse of decongestants in half of the patients
Philippe Gevaert
Els Mehuys
Guy Brusselle
T Van Hees
Thierry Christiaens
Lucas Van Bortel
Inge Van Tongelen
Jean Paul Remon
Koen Boussery
C3
Conference
2014
Should we pursue pulmonary vasodilation in patients with COPD?
Guy Brusselle
Editorial material
2014
Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma
M Kupczyk
B Dahlen
PJ Sterk
E Nizankowska-Mogilnicka
A Papi
EH Bel
P Chanez
PH Howarth
ST Holgate
Guy Brusselle
et al.
A1
Journal Article
in
ALLERGY
2014
Susceptibility to chronic mucus hypersecretion, a genome wide association study
Akkelies E Dijkstra
Joanna Smolonska
Maarten van den Berge
Ciska Wijmenga
Pieter Zanen
Marjan A Luinge
Mathieu Platteel
Jan-Willem Lammers
Magnus Dahlback
Kerrie Tosh
et al.
A1
Journal Article
in
PLOS ONE
2014
Targeting immune pathways for therapy in asthma and chronic obstructive pulmonary disease
Guy Brusselle
Ken Bracke
A2
Journal Article
in
ANNALS OF THE AMERICAN THORACIC SOCIETY
2014
The effect of chronic cigarette smoke exposure on gut microbial diversity in healthy mice
Liesbeth Allais
Frederiek-Maarten Kerckhof
Stephanie Verscheure
Ken Bracke
Rebecca De Smet
Debby Laukens
Pieter Van den Abbeele
Martine De Vos
Nico Boon
Guy Brusselle
et al.
C3
Conference
2014
The effect of chronic cigarette smoke exposure on the gut microbiome in healthy mice
Liesbeth Allais
Frederiek-Maarten Kerckhof
Stephanie Verscheure
Ken Bracke
Rebecca De Smet
Debby Laukens
Pieter Van den Abbeele
Martine De Vos
Nico Boon
Guy Brusselle
et al.
C3
Conference
2014
Trustworthy guidelines on severe asthma thanks to ERS and ATS
Guy Brusselle
Monica Kraft
Editorial material
2014
Usage of inhalation devices in asthma and chronic obstructive pulmonary disease: a Delphi consensus statement
Vincent Ninane
Guy Brusselle
Louis Renaud
Lieven Dupont
Giuseppe Liistro
Wilfried De Backer
Marc Schlesser
Walter Vincken
A1
Journal Article
in
EXPERT OPINION ON DRUG DELIVERY
2014
Use of tiotropium Respimat versus HandiHaler and mortality in patients with COPD
Katia MC Verhamme
Miriam CJM Sturkenboom
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2014
Why doesn't reducing exacerbations decrease COPD mortality?
Guy Brusselle
Editorial material
2014
β-adrenoceptor blockers and pulmonary function in the general population: the Rotterdam Study
Daan W Loth
Guy Brusselle
Lies Lahousse
Albert Hofman
Hubert GM Leufkens
Bruno H Stricker
A1
Journal Article
in
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
2014
2013
Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial
Guy Brusselle
Christine VanderStichele
Paul Jordens
René Deman
Hans Slabbynck
Veerle Ringoet
Geert Verleden
Ingel K Demedts
Katia Verhamme
ANJA DELPORTE
et al.
A1
Journal Article
in
THORAX
2013
COPD awareness survey: do Belgian pulmonary physicians comply with the GOLD guidelines 2010?
M Decramer
Guy Brusselle
J Buffels
JL Corhay
W De Backer
JM Degryse
W Janssens
E Marchand
P Van den Brande
W Vincken
et al.
A1
Journal Article
in
ACTA CLINICA BELGICA
2013
Challenges of COPD diagnosis
David Price
Guy Brusselle
A2
Journal Article
in
EXPERT OPINION ON MEDICAL DIAGNOSTICS
2013
Chronic cigarette smoke exposure alters the murine gut microbiome
Liesbeth Allais
Frederiek-Maarten Kerckhof
Stephanie Verschuere
Ken Bracke
Rebecca De Smet
Debby Laukens
Martine De Vos
Nico Boon
Guy Brusselle
Tom Van de Wiele
et al.
C3
Conference
2013
Chronic cigarette smoke exposure alters the murine gut microbiome
Liesbeth Allais
Frederiek-Maarten Kerckhof
Stephanie Verschuere
Ken Bracke
Rebecca De Smet
Debby Laukens
Martine De Vos
Nico Boon
Guy Brusselle
Tom Van de Wiele
et al.
C3
Conference
2013
Chronic cigarette smoke exposure alters the murine gut microbiome
Liesbeth Allais
Frederiek-Maarten Kerckhof
Stephanie Verscheure
Ken Bracke
Rebecca De Smet
Debby Laukens
Martine De Vos
Nico Boon
Guy Brusselle
Tom Van de Wiele
et al.
C3
Conference
2013
Chronic obstructive pulmonary disease (COPD) exacerbations and carotid artery plaques : the Rotterdam study
Lies Lahousse
Quirijn JA van den Bouwhuijsen
Daan W Loth
Guy Joos
Albert Hofman
Jacqueline CM Witteman
Aad van der Lugt
Guy Brusselle
Bruno C Stricker
C3
Conference
2013
Chronic obstructive pulmonary disease and cerebral microbleeds: the Rotterdam study
Lies Lahousse
Meike W Vernooij
Sirwan KL Darweesh
Saloua Akoudad
Daan W Loth
Guy Joos
Albert Hofman
Bruno H Stricker
M Arfan Ikram
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2013
Chronic obstructive pulmonary disease and lipid core carotid artery plaques in the elderly: the Rotterdam Study
Lies Lahousse
Quirijn JA van den Bouwhuijsen
Daan W Loth
Guy Joos
Albert Hofman
Jacqueline CM Witteman
Aad van der Lugt
Guy Brusselle
Bruno H Stricker
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2013
Contribution of four common pulmonary function tests to diagnosis of patients with respiratory symptoms : a prospective cohort study
Marc Decramer
Wim Janssens
Eric Derom
Guy Joos
Vincent Ninane
René Deman
Dirk Van Renterghem
Giuseppe Liistro
Kris Bogaerts
the Belgian Pulmonary Study Investigators
et al.
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2013
Eosinophilic airway inflammation in nonallergic asthma
Guy Brusselle
Tania Maes
Ken Bracke
Editorial material
2013
Exposing a deadly alliance: novel insights into the biological links between COPD and lung cancer
Karim Vermaelen
Guy Brusselle
A1
Journal Article
in
PULMONARY PHARMACOLOGY & THERAPEUTICS
2013
Frailty affects quality of spirometry : the Rotterdam study
Lies Lahousse
DW Loth
VJA Verlinden
G Ziere
M Zillikens
AG Uitterlinden
F Rivadeneira
H Tiemeier
M Ikram
A Hofman
et al.
C3
Conference
2013
Hand-held fractional exhaled nitric oxide measurements as a non-invasive indicator of systemic inflammation in Crohn's disease
Laure-Ann Quenon
Pieter Hindryckx
Martine De Vos
Danny De Looze
Guy Joos
Guy Brusselle
Harald Peeters
A1
Journal Article
in
JOURNAL OF CROHNS & COLITIS
2013
Impact of frailty on interpretability of spirometry : the Rotterdam study
Lies Lahousse
Bastiaan Maes
DW Loth
VJA Verlinden
G Ziere
MC Zillikens
A Uitterlinden
F Rivadeneira
H Tiemeier
MA Ikram
et al.
C3
Conference
2013
Integrating real-life studies in the global therapeutic research framework
Nicolas Roche
Helen K Reddel
Alvar Agusti
Eric D Bateman
Jerry A Krishnan
Richard J Martin
Alberto Papi
Dirkje Postma
Mike Thomas
Guy Brusselle
et al.
A1
Journal Article
in
LANCET RESPIRATORY MEDICINE
2013
InternationaL cross-sectIonAl and longItudinal assessment on aSthma cONtrol in European adult patients: the LIAISON study protocol
Fulvio Braido
Guy Brusselle
Eleonora Ingrassia
Gabriele Nicolini
David Price
Nicolas Roche
Joan B Soriano
Heinrich Worth
A1
Journal Article
in
BMC PULMONARY MEDICINE
2013
Leptin as regulator of pulmonary immune responses: involvement in respiratory diseases
Juanita HJ Vernooy
Niki DJ Ubags
Guy Brusselle
Jan Tavernier
Benjamin T Suratt
Guy Joos
Emiel FM Wouters
Ken Bracke
A1
Journal Article
in
PULMONARY PHARMACOLOGY & THERAPEUTICS
2013
Long-acting bronchodilators improve Health Related Quality of Life in patients with COPD
Fulvio Braido
Ilaria Baiardini
Mario Cazzola
Guy Brusselle
Fiorenza Marugo
Giorgio Walter Canonica
A1
Journal Article
in
RESPIRATORY MEDICINE
2013
Normal spirometry values in healthy elderly: the Rotterdam Study
Daan Willem Loth
Till Ittermann
Lies Lahousse
Albert Hofman
Hubert Gerardus Maria Leufkens
Guy Brusselle
Bruno Hugo Stricker
A1
Journal Article
in
EUROPEAN JOURNAL OF EPIDEMIOLOGY
2013
Of flies, mice and men : a systematic approach to understanding the early life origins of chronic lung disease
Susanne Krauss-Etschmann
Andrew Bush
Saverio Bellusci
Guy Brusselle
Sven Erik K Dahlén
Stefan Dehmel
Oliver Eickelberg
Greg Gibson
Machteld N Hylkema
Petra Knaus
et al.
A1
Journal Article
in
THORAX
2013
Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma
Philippe Gevaert
LIEN CALUS
Thibaut Van Zele
Katrien Blomme
Natalie De Ruyck
WOUTER BAUTERS
Peter Hellings
Guy Brusselle
Dirk De Bacquer
Paul Van Cauwenberge
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2013
Pulmonary function is associated with pulmonary artery systolic pressure in the general population : the Rotterdam study
Daan Loth
Lies Lahousse
Maarten Leening
Bouwe Krijthe
Janine Felix
Henning Tiede
Ardeschir Ghofrani
Oscar Franco
Bruno Stricker
Guy Brusselle
C3
Conference
2013
Risk-to-benefit ratio of inhaled corticosteroids in patients with COPD
David Price
Barbara Yawn
Guy Brusselle
Andrea Rossi
A1
Journal Article
in
PRIMARY CARE RESPIRATORY JOURNAL
2013
Role of CXCL13 in cigarette smoke-induced lymphoid follicle formation and chronic obstructive pulmonary disease
Ken Bracke
Fien Verhamme
Leen Seys
Claudie Bantsimba-Malanda
Danen Mootoosamy Cunoosamy
Ronald Herbst
Hamida Hammad
Bart Lambrecht
Guy Joos
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2013
Should clinicians use omalizumab for the treatment of nasal polyps?: reply
LIEN CALUS
Peter Hellings
Guy Brusselle
Claus Bachert
Philippe Gevaert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2013
Spirometric reference values for an East-African population
Sanctus Musafiri
Jan Van Meerbeeck
Laurent Musango
Eric Derom
Guy Brusselle
Guy Joos
Claver Rutayisire
guy joos
A1
Journal Article
in
RESPIRATION
2013
Statins, systemic inflammation and risk of death in COPD: the Rotterdam Study
Lies Lahousse
Daan W Loth
Guy Joos
Albert Hofman
Hubert GM Leufkens
Guy Brusselle
Bruno H Stricker
A1
Journal Article
in
PULMONARY PHARMACOLOGY & THERAPEUTICS
2013
The role of soluble guanylyl cyclase in Chronic Obstructive Pulmonary Disease
Constantinos Glynos
Lisa Dupont
Theodoros Vassilakopoulos
Andreas Papapetropoulos
Peter Brouckaert
Athanassios Giannis
Guy Joos
Ken Bracke
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2013
Use of tiotropium Respimat Soft Mist Inhaler versus HandiHaler and mortality in patients with COPD
Katia MC Verhamme
Ana Afonso
Silvana Romio
Bruno C Stricker
Guy Brusselle
Miriam CJM Sturkenboom
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2013
2012
Altered cigarette smoke-induced lung inflammation due to ablation of Grx1
Ine Kuipers
Ken Bracke
Guy Brusselle
Scott W Aesif
Renske Krijgsman
Ilja C Arts
Emiel FM Wouters
Niki L Reynaert
A1
Journal Article
in
PLOS ONE
2012
COPD is associated with reduced pulmonary interstitial expression of pentraxin-3
Geert Van Pottelberge
Ken Bracke
Nele Pauwels
Frank Vermassen
Guy Joos
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2012
Chronic obstructive pulmonary disease and comorbidities through the eyes of the patient
Pauline Boeckxstaens
Marina Deregt
Piet Vandesype
Sara Willems
Guy Brusselle
An De Sutter
A1
Journal Article
in
CHRONIC RESPIRATORY DISEASE
2012
Chronic rejection pathology after orthotopic lung transplantation in mice : the development of a murine BOS model and its drawbacks
Stephanie De Vleeschauwer
Wolfgang Jungraithmayr
Shana Wauters
Stijn Willems
Manuela Rinaldi
Annemie Vaneylen
Stijn Verleden
Anna Willems-Widyastuti
Ken Bracke
Guy Brusselle
et al.
A1
Journal Article
in
PLOS ONE
2012
Cigarette smoke and the terminal ileum: increased autophagy in murine follicle-associated epithelium and Peyer's patches
Stephanie VERSCHUERE
Liesbeth Allais
Ken Bracke
Saskia Lippens
Rebecca De Smet
Peter Vandenabeele
Guy Brusselle
Claude Cuvelier
A1
Journal Article
in
HISTOCHEMISTRY AND CELL BIOLOGY
2012
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction
Jemma B Wilk
Nick RG Shrine
Laura R Loehr
Jing Hua Zhao
Ani Manichaikul
Lorna M Lopez
Albert Vernon Smith
Susan R Heckbert
Joanna Smolonska
Wenbo Tang
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2012
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function
Dana B Hancock
María Soler Artigas
Sina A Gharib
Amanda Henry
Ani Manichaikul
Adaikalavan Ramasamy
Daan W Loth
Medea Imboden
Beate Koch
Wendy L McArdle
et al.
A1
Journal Article
in
PLOS GENETICS
2012
I have taken my umbrella, so of course it does not rain
DS Postma
Guy Brusselle
A Bush
JW Holloway
A1
Journal Article
in
THORAX
2012
Omalizumab is effective in allergic and non-allergic patients with nasal polyps and asthma
Philippe Gevaert
LIEN CALUS
Thibaut Van Zele
Katrien Blomme
Natalie De Ruyck
WOUTER BAUTERS
P Hellings
Dirk De Bacquer
Guy Brusselle
Paul Van Cauwenberge
et al.
C3
Conference
2012
Onset of bronchodilation with fluticasone/formoterol combination versus fluticasone/salmeterol in an open-label, randomized study
René Aalbers
Guy Brusselle
Tammy McIver
Birgit Grothe
Anna Bodzenta-Lukaszyk
A1
Journal Article
in
ADVANCES IN THERAPY
2012
Patient-centred assessment of COPD in primary care: experience from a cross-sectional study of health-related quality of life in Europe
Paul W Jones
Guy Brusselle
Roberto W Dal Negro
Montse Ferrer
Peter Kardos
Mark L Levy
Thierry Perez
Juan José Soler Cataluña
Thys van der Molen
Lukasz Adamek
et al.
A1
Journal Article
in
PRIMARY CARE RESPIRATORY JOURNAL
2012
Real-life effectiveness of extrafine beclometasone dipropionate/formoterol in adults with persistent asthma according to smoking status
Guy Brusselle
Rudi Peché
Paul Van den Brande
Albert Verhulst
Wim Hollanders
Jacques Bruhwyler
A1
Journal Article
in
RESPIRATORY MEDICINE
2012
Risk of cardiac valve regurgitation with dopamine agonist use in Parkinson's disease and hyperprolactinaemia: a multi-country, nested case-control study
Gianluca Trifirò
M Mostafa Mokhles
Jeanne P Dieleman
Eva M van Soest
Katia Verhamme
Giampiero Mazzaglia
Ron Herings
Cynthia de Luise
Douglas Ross
Guy Brusselle
et al.
A1
Journal Article
in
DRUG SAFETY
2012
Smoke decreases reversible oxidations S-glutathionylation and S-nitrosylation in mice
Ine Kuipers
Ken Bracke
Guy Brusselle
Emiel F Wouters
Niki L Reynaert
A1
Journal Article
in
FREE RADICAL RESEARCH
2012
Targeting interleukin-4 in asthma : lost in translation?
Tania Maes
Guy Joos
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
2012
The effect of cigarette smoke on mucosal immunity of the terminal ileum
Stephanie VERSCHUERE
Claude Cuvelier
Guy Brusselle
Dissertation
2012
The risk of new onset heart failure associated with dopamine agonist use in Parkinson's disease
M Mostafa Mokhles
Gianluca Trifirò
Jeanne P Dieleman
Mendel D Haag
Eva M van Soest
Katia MC Verhamme
Giampiero Mazzaglia
Ron Herings
Cynthia de Luise
Douglas Ross
et al.
A1
Journal Article
in
PHARMACOLOGICAL RESEARCH
2012
Tiotropium Handihaler and the risk of cardio- or cerebrovascular events and mortality in patients with COPD
KMC Verhamme
ASM Afonso
C van Noord
MD Haag
PJ Koudstaal
Guy Brusselle
MCJM Sturkenboom
A1
Journal Article
in
PULMONARY PHARMACOLOGY & THERAPEUTICS
2012
2011
Activation of the WNT/β-catenin pathway attenuates experimental emphysema
Nikolaus Kneidinger
Ali Oender Yildirim
Lens Callegari
Shinji Takenaka
Maria Magdalena Stein
Rio Dumitrascu
Alexander Bohla
Ken Bracke
Rory E Morty
Guy Brusselle
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2011
Alternatively activated macrophages and impaired phagocytosis of S-aureus in chronic rhinosinusitis
Olga Krysko
Gabriële Holtappels
Nan Zhang
Malgorzata Kubica
Kim Deswarte
Lara Derycke
Sofie Claeys
Hamida Hammad
Guy Brusselle
Peter Vandenabeele
et al.
A1
Journal Article
in
ALLERGY
2011
COPD in the general population: prevalence, incidence and survival
Ana SM Afonso
Katia MC Verhamme
Miriam CJM Sturkenboom
Guy Brusselle
A1
Journal Article
in
RESPIRATORY MEDICINE
2011
Chronic smoke exposure is associated with autophagy in murine Peyer's patches
Stephanie VERSCHUERE
Ken Bracke
Rebecca De Smet
Liesbeth Allais
Guy Brusselle
Claude Cuvelier
C3
Conference
2011
Cigarette smoking alters epithelial apoptosis and immune composition in murine GALT
Stephanie VERSCHUERE
Ken Bracke
Tine Demoor
Maud Plantinga
Phebe Verbrugghe
Liesbeth Ferdinande
Bart Lambrecht
Guy Brusselle
Claude Cuvelier
A1
Journal Article
in
LABORATORY INVESTIGATION
2011
Cigarette smoking alters intestinal barrier function and Peyer's Patch composition
Stephanie VERSCHUERE
Ken Bracke
Tine Demoor
Maud Plantinga
Bart Lambrecht
Guy Brusselle
Claude Cuvelier
C3
Conference
2011
Effect of different asthma treatments on risk of cold-related exacerbations
HK Reddel
C Jenkins
S Quirce
MR Sears
ED Bateman
PM O'Byrne
M Humbert
R Buhl
T Harrison
Guy Brusselle
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2011
Exacerbation of cigarette smoke-induced pulmonary inflammation by Staphylococcus aureus enterotoxin B in mice
Wouter Huvenne
Ellen Lanckacker
Olga Krysko
Ken Bracke
Tine Demoor
Peter W Hellings
Guy Brusselle
Guy Joos
Claus Bachert
Tania Maes
A1
Journal Article
in
RESPIRATORY RESEARCH
2011
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
Maria Soler Artigas
Daan W Loth
Louise V Wain
Sina A Gharib
Ma'en Obeidat
Wenbo Tang
Guangju Zhai
Jing Hua Zhao
Albert Vernon Smith
Jennifer E Huffman
et al.
A1
Journal Article
in
NATURE GENETICS
2011
Health-related quality of life in patients by COPD severity within primary care in Europe
PW Jones
Guy Brusselle
RW Dal Negro
M Ferrer
P Kardos
ML Levy
T Perez
JJ Soler-Cataluna
T van der Molen
L Adamek
et al.
A1
Journal Article
in
RESPIRATORY MEDICINE
2011
Inhaled anticholinergic drugs and risk of acute urinary retention
Ana SM Afonso
Katia MC Verhamme
Bruno HC Stricker
Miriam CJM Sturkenboom
Guy Brusselle
A1
Journal Article
in
BJU INTERNATIONAL
2011
Interleukin 6 (IL6) plasma levels, common variation In the IL6 gene and the risk of chronic obstructive pulmonary disease : a prospective population-based cohort study
Lies Lahousse
YANNICK VAN DURME
KMC Verhamme
L Stolk
M Eijgelsheim
D Loth
AG Uitterlinden
M Breteler
Guy Joos
A Hofman
et al.
C3
Conference
2011
Mendelian randomization study of interleukin-6 in chronic obstructive pulmonary disease
YANNICK VAN DURME
Lies Lahousse
Katia MC Verhamme
Lisette Stolk
Mark Eijgelsheim
Daan W Loth
Andre G Uitterlinden
Monique MB Breteler
Guy Joos
Albert Hofman
et al.
A1
Journal Article
in
RESPIRATION
2011
MicroRNA expression in induced sputum of smokers and patients with chronic obstructive pulmonary disease
Geert Van Pottelberge
Pieter Mestdagh
Ken Bracke
Olivier Thas
YANNICK VAN DURME
Guy Joos
Jo Vandesompele
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2011
Microscopic polyangiitis involving the breast
MIEKE DEVINCK
Bert Vander Cruyssen
Kathleen Lambein
Filip De Keyser
Marleen Praet
Guy Brusselle
A1
Journal Article
in
ACTA CLINICA BELGICA
2011
Neomacrolides in the treatment of patients with severe asthma and/or bronchiectasis : a retrospective observational study
Mathieu Coeman
YANNICK VAN DURME
Fre Bauters
Ellen Deschepper
Ingel Demedts
Peter Smeets
Guy Joos
Guy Brusselle
A2
Journal Article
in
THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE
2011
New insights into the immunology of chronic obstructive pulmonary disease
Guy Brusselle
Guy Joos
Ken Bracke
A1
Journal Article
in
LANCET
2011
Prevalence of atopy, asthma and COPD in an urban and a rural area of an African country
Sanctus Musafiri
Jan Van Meerbeeck
Laurent Musango
Guy Brusselle
Guy Joos
Benoit Seminega
Claver Rutayisire
A1
Journal Article
in
RESPIRATORY MEDICINE
2011
Properties of the COPD assessment test in a cross-sectional European study
PW Jones
Guy Brusselle
RW Dal Negro
M Ferrer
P Kardos
ML Levye
T Perez
JJ Soler Cataluña
T van der Molen
L Adamek
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2011
Role of IL-1α and the Nlrp3/caspase-1/IL-1β axis in cigarette smoke-induced pulmonary inflammation and COPD
NS Pauwels
Ken Bracke
Lisa Dupont
Geert Van Pottelberge
Sharen Provoost
Tom Vanden Berghe
Peter Vandenabeele
Bart Lambrecht
Guy Joos
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2011
The role of ChemR23 in the induction and resolution of cigarette smoke-induced inflammation
Tine Demoor
Ken Bracke
Lisa Dupont
Maud Plantinga
Benjamin Bondue
Marie-Odile Roy
Vincent Lannoy
Bart Lambrecht
Guy Brusselle
Guy Joos
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2011
Viruses and bacteria in acute asthma exacerbations : a GA2LEN-DARE* systematic review
NG Papadopoulos
I Christodoulou
G Rohde
I Agache
C Almqvist
A Bruno
S Bonini
L Bont
A Bossios
J Bousquet
et al.
A1
Journal Article
in
ALLERGY
2011
2010
A 41-year-old man with breast cancer and dyspnoea: an exceptional complication in an uncommon disease
VERONIQUE BUYSE
Guy Brusselle
Veronique Cocquyt
Simon Van Belle
A1
Journal Article
in
ACTA CLINICA BELGICA
2010
Behandeling van COPD : waar ligt de rol van de officina-apotheker?
Els Mehuys
Koen Boussery
Els Adriaens
Lucas Van Bortel
Leen De Bolle
Inge Van Tongelen
Jean Paul Remon
Guy Brusselle
A4
Journal Article
in
FARMACEUTISCH TIJDSCHRIFT VOOR BELGIE [1971]
2010
COPD management in primary care : an observational, community pharmacy-based study
Els Mehuys
Koen Boussery
Els Adriaens
Lucas Van Bortel
Leen De Bolle
Inge Van Tongelen
Jean Paul Remon
Guy Brusselle
C3
Conference
2010
COPD management in primary care: an observational, community pharmacy-based study
Els Mehuys
Koen Boussery
Els Adriaens
Lucas Van Bortel
Leen De Bolle
Inge Van Tongelen
Jean Paul Remon
Guy Brusselle
A1
Journal Article
in
ANNALS OF PHARMACOTHERAPY
2010
Chronic cough in upper airway diseases
Jean-Baptiste Watelet
Thibaut Van Zele
Guy Brusselle
A1
Journal Article
in
RESPIRATORY MEDICINE
2010
Cigarette smoke induces PTX3 expression in pulmonary veins of mice in an IL-1 dependent manner
Nele Pauwels
Ken Bracke
Tania Maes
Geert Van Pottelberge
Cecilia Garlanda
Alberto Mantovani
Guy Joos
Guy Brusselle
A1
Journal Article
in
RESPIRATORY RESEARCH
2010
Different regulation of cigarette smoke induced inflammation in upper versus lower airways
Wouter Huvenne
Claudina Perez Novo
Lara Derycke
Natalie De Ruyck
Olga Krysko
Tania Maes
Nele Pauwels
Lander Robays
Ken Bracke
Guy Joos
et al.
A1
Journal Article
in
RESPIRATORY RESEARCH
2010
Enhanced deposition of low-molecular-weight hyaluronan in lungs of cigarette smoke-exposed mice
Ken Bracke
Mieke A Dentener
Eleni Papakonstantinou
Juhanita HJ Vernooy
Tine Demoor
Nele Pauwels
Jack Cleutjens
Robert Jan van Suylen
Guy Joos
Guy Brusselle
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
2010
GINA en GOLD, een update
An Simpelaere
Eric Derom
Guy Brusselle
Guy Joos
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2010
Hedgehog-interacting protein is a COPD susceptibility gene: the Rotterdam Study
YANNICK VAN DURME
M Eijgelsheim
Guy Joos
A Hofman
AG Uitterlinden
Guy Brusselle
BHC Stricker
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2010
Increased T-regulatory cells in lungs and draining lymph nodes in a murine model of COPD
Tine Demoor
Ken Bracke
Guy Joos
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2010
Leptin modulates innate and adaptive immune cell recruitment after cigarette smoke exposure in mice
JHJ Vernooy
Ken Bracke
NEA Drummen
NSA Pauwels
Lennart Zabeau
RJ van Suylen
Jan Tavernier
Guy Joos
EFM Wouters
Guy Brusselle
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2010
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
Dana B Hancock
Mark Eijgelsheim
Jemma B Wilk
Sina A Gharib
Laura R Loehr
Kristin D Marciante
Nora Franceschini
YANNICK VAN DURME
Ting-Hsu Chen
R Graham Barr
et al.
A1
Journal Article
in
NATURE GENETICS
2010
Plasmacytoid dendritic cells in pulmonary lymphoid follicles of patients with COPD
Geert Van Pottelberge
Ken Bracke
Sarah Van den Broeck
Suzanne M Reinartz
Cornelis M van Drunen
Emiel FM Wouters
Geert M Verleden
Frank Vermassen
Guy Joos
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2010
Plasmacytoid dendritic cells in pulmonary lymphoid follicles of patients with COPD
Geert Van Pottelberge
Ken Bracke
Sarah Van den Broeck
Suzanne Reinartz
Cornelis M van Drunen
Emiel FM Wouters
Geert M Verleden
Frank Vermassen
Guy Joos
Guy Brusselle
C3
Conference
2010
Reduced expression of pentraxin-3 in the lungs of patients with COPD
Geert Van Pottelberge
Ken Bracke
N Pauwels
YANNICK VAN DURME
GM Verleden
Frank Vermassen
Guy Joos
Guy Brusselle
C3
Conference
2010
Rheumatoid arthritis and interstitial lung disease
Guy Brusselle
Editorial material
2010
Selective accumulation of Langerhans-type dendritic cells in small airways of patients with COPD
Geert Van Pottelberge
Ken Bracke
Ingel Demedts
Kim De Rijck
Suzanne Reinartz
Cornelis van Drunen
Geert Verleden
Frank Vermassen
Guy Joos
Guy Brusselle
A1
Journal Article
in
RESPIRATORY RESEARCH
2010
The role of interleukin-6 in pulmonary and systemic manifestations in a murine model of chronic obstructive pulmonary disease
Nele Pauwels
Ken Bracke
Tania Maes
Charles Pilette
Guy Joos
Guy Brusselle
A1
Journal Article
in
EXPERIMENTAL LUNG RESEARCH
2010
2009
"Real-life" effectiveness of omalizumab in patients with severe persistent allergic asthma: The PERSIST study
Guy Brusselle
A Michils
R Louis
L Dupont
BV de Maele
A Delobbe
C Pilette
CS Lee
S Gurdain
S Vancayzeele
et al.
A1
Journal Article
in
RESPIRATORY MEDICINE
2009
C-reactive protein levels, haplotypes and the risk of incident chronic obstructive pulmonary disease
YANNICK VAN DURME
Katia Verhamme
Albert-Jan Aarnoudse
Geert Van Pottelberge
Albert Hofman
Jacqueline Witteman
Guy Joos
Guy Brusselle
Bruno Stricker
A1
Journal Article
in
American Journal of Respiratory Critical Care Medicine
2009
CCR7 Modulates Pulmonary and Lymph Node Inflammatory Responses in Cigarette Smoke-Exposed Mice
Tine Demoor
Ken Bracke
Karim Vermaelen
Lisa Dupont
Guy Joos
Guy Brusselle
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2009
Cigarette smoke induces apoptosis in the follicle-associated epithelium of murine Peyer's patches
Stephanie VERSCHUERE
Philip Vlummens
Phebe Verbrugghe
Ken Bracke
Isabelle Rottiers
Guy Brusselle
Claude Cuvelier
C3
Conference
2009
Concomittant inhalation of cigarette smoke and aerosolized protein activates airway dendritic cells and induces allergic airway inflammation in a TLR-independent way
Lander Robays
Ellen Lanckacker
Katrien Moerloose
Tania Maes
Ken Bracke
Guy Brusselle
Guy Joos
Karim Vermaelen
A1
Journal Article
in
Journal of Immunology
2009
Decreased FOXP3 protein expression in patients with asthma
Sharen Provoost
Tania Maes
YANNICK VAN DURME
Philippe Gevaert
Claus Bachert
C.B. Schmidt-Weber
Guy Brusselle
Guy Joos
Kurt Tournoy
A1
Journal Article
in
Allergy
2009
Different regulation of cigarette smoke induced inflammation in upper versus lower airways: findings from a mouse model
Wouter Huvenne
Claudina Perez Novo
Natalie De Ruyck
Nele Pauwels
Lander Robays
Tania Maes
Paul Van Cauwenberge
Guy Joos
Guy Brusselle
Claus Bachert
C3
Conference
2009
Enhanced pulmonary leptin expression in patients with severe COPD and asymptomatic smokers
JHJ Vernooy
NEA Drummen
RJ Van Suylen
RHE Cloots
GM Moller
Ken Bracke
S Zuyderduyn
MA Dentener
Guy Brusselle
PS Hiemstra
et al.
A1
Journal Article
in
Thorax
2009
Extrapulmonary manifestations of chronic obstructive pulmonary disease in a mouse model of chronic cigarette smoke exposure
Ken Bracke
Guy Joos
Guy Brusselle
A1
Journal Article
in
American Journal of Respiratory Cell and Molecular Biology
2009
Lymphoid follicles in (very) severe COPD: beneficial or harmful?
Guy Brusselle
Tine Demoor
Ken Bracke
C.-A. Brandsma
W. Timens
A1
Journal Article
in
European Respiratory Journal
2009
Matrix Metalloproteinase 12, Asthma, and COPD
Guy Brusselle
Editorial material
2009
Prevalence, incidence and lifetime risk for the development of COPD in the elderly : the Rotterdam study
YANNICK VAN DURME
Katia Verhamme
Theo Stijnen
Frank Van Rooij
Geert Van Pottelberge
Albert Hofman
Guy Joos
Bruno Stricker
Guy Brusselle
A1
Journal Article
in
CHEST
2009
Role of Lymphotoxin (alpha) in Cigarette Smoke-Induced Inflammation and Lymphoid Neogenesis
Tine Demoor
Ken Bracke
Tania Maes
BERNARD VANDOOREN
Dirk Elewaut
Charles Pilette
Guy Joos
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2009
Role of tachykinin NK1 receptor in a murine model of cigarette-smoke induced pulmonary inflammation
Katelijne De Swert
Ken Bracke
Tine Demoor
Guy Brusselle
Guy Joos
A1
Journal Article
in
Respiratory Research
2009
The Role of Dendritic Cells in the Pathogenesis of COPD: Liaison Officers in the Front Line
Geert Van Pottelberge
Ken Bracke
Guy Joos
Guy Brusselle
A1
Journal Article
in
COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
2009
2008
Comment on "cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent"
Tania Maes
Ken Bracke
Guy Joos
Guy Brusselle
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2008
Dendritic cells in chronic obstructive pulmonary disease - New players in an old game
M TSOUMAKIDOU
INGEL DEMEDTS
Guy Brusselle
PK JEFFERY
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2008
Effectiveness of pharmacist intervention for asthma control improvement
Els Mehuys
Lucas Van Bortel
Leen De Bolle
Inge Van Tongelen
Lieven Annemans
Jean Paul Remon
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2008
Inhaled anticholinergic drugs and risk of acute urinary retention
ASM AFONSO
KMC VERHAMME
BC STRICKER
Guy Brusselle
MCJM STURKENBOOM
C3
Conference
2008
Outpatient Pharmacotherapy
Guy Brusselle
Bookchapter
in
Pharmacotherapy of Asthma
2008
Pharmacist interventions in asthma - Reply
E MEHUYS
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2008
TNF alpha receptor genotype influences smoking-induced muscle-fibre-type shift and atrophy in mice
Boel De Paepe
Guy Brusselle
Tania Maes
Kim Creus
Sophie D'hose
Nele D'Haese
Ken Bracke
An D'hulst
Guy Joos
Jan De Bleecker
A1
Journal Article
in
ACTA NEUROPATHOLOGICA
2008
2007
Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease
Ingel Demedts
Ken Bracke
Geert Van Pottelberge
Dries Testelmans
Geert M Verleden
Frank Vermassen
Guy Joos
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2007
Bilateral spontaneous pneumothorax in a patient with pulmonary rheumatoid nodules, secondary infected by Aspergillus
L WINNE
Marleen Praet
Guy Brusselle
Eric Veys
Herman Mielants
A1
Journal Article
in
CLINICAL RHEUMATOLOGY
2007
Chemokine receptor CCR2 but not CCR5 or CCR6 mediates the increase in pulmonary dendritic cells during allergic airway inflammation.
Lander Robays
Tania Maes
S LEBECQUE
SA LIRA
WA KUZIEL
Guy Brusselle
Guy Joos
Karim Vermaelen
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2007
Cigarette smoke-induced pulmonary inflammation, but not airway remodelling, is attenuated in chemokine receptor 5-deficient mice
Ken Bracke
An D'hulst
Tania Maes
INGEL DEMEDTS
Katrien Moerloose
WA KUZIEL
Guy Joos
Guy Brusselle
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
2007
Dendritic cell maturity and obstructive airway disease
Ingel Demedts
Guy Joos
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2007
Interstitiële longafwijkingen bij reumatoide artritis
E VAN SCHOOTE
L VANWALLEGHEM
F DE KEYSER
Guy Joos
Guy Brusselle
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2007
Mechanisms of virus-induced asthma exacerbations: state-of-the-art. A GA(2)LEN and InterAirways document
NG PAPADOPOULOS
P XEPAPADAKI
P MALLIA
Guy Brusselle
Jean-Baptiste Watelet
M XATZIPSALTI
G FOTEINOS
CM VAN DRUNEN
WJ FOKKENS
C D'AMBROSIO
et al.
A1
Journal Article
in
ALLERGY
2007
Pulmonary dendritic cells: playing ball in the BAL?
IK DEMEDTS
Guy Joos
Guy Brusselle
Editorial material
2007
Pulmonary-renal syndromes
Guy Brusselle
A1
Journal Article
in
ACTA CLINICA BELGICA
2007
Re: Pulmonary arterial hypertension in connective tissue diseases
Vanessa Smith
Michel De Pauw
Guy Brusselle
Jens Van Praet
Filip De Keyser
A1
Journal Article
in
RHEUMATOLOGY
2007
Role of dendritic cells and matrix metalloproteinase-12 in the pathogenesis of COPD
Ingel Demedts
Guy Brusselle
Guy Joos
Romain Pauwels
Dissertation
2007
Sporen wij astmapatiënten aan tot zelfzorg? : een enquête bij Vlaamse huisartsen en pneumologen : brief aan de redactie
Els Mehuys
Lucas Van Bortel
Guy Brusselle
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2007
Systeemsclerose
Vanessa Smith
Guy Brusselle
Michel De Pauw
Daniël De Wolf
A2
Journal Article
in
Tijdschrift voor Geneeskunde
2007
TNF alpha receptor signalling influences the expression of myosin heavy chain isoforms in musculus gastrocnemius of the mouse
Boel De Paepe
Kim Creus
Sophie D'hose
Guy Brusselle
Jan De Bleecker
C3
Conference
2007
2006
Animal models of allergen-induced tolerance in asthma: are T-regulatory-1 cells (Tr-1) the solution for T-helper-2 cells (Th-2) in asthma?
Kurt Tournoy
Chris Van Hove
Johan Grooten
K MOERLOOSE
Guy Brusselle
Guy Joos
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
2006
Cigarette smoke exposure facilitates allergic sensitization in mice
Katrien Moerloose
Lander Robays
Tania Maes
Guy Brusselle
Kurt Tournoy
Guy Joos
A1
Journal Article
in
RESPIRATORY RESEARCH
2006
Cigarette smoke-induced pulmonary inflammation and emphysema are attenuated in CCR6-deficient mice
Ken Bracke
An D'hulst
Tania Maes
Katrien Moerloose
Ingel Demedts
S LEBECQUE
Guy Joos
Guy Brusselle
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2006
Corticosteroids and the risk of atrial fibrillation
CS VAN DER HOOFT
J HEERINGA
Guy Brusselle
A HOFMAN
JCM WITTEMAN
JH KINGMA
MCJM STURKENBOOM
BHC STRICKER
A1
Journal Article
in
ARCHIVES OF INTERNAL MEDICINE
2006
Different roles for human lung dendritic cell subsets in pulmonary immune defense mechanisms
Ingel Demedts
Ken Bracke
Tania Maes
Guy Joos
Guy Brusselle
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
2006
Elevated MMP-12 protein levels in induced sputum from patients with COPD
IK DEMEDTS
A MOREL-MONTERO
S LEBECQUE
Y PACHECO
D CATALDO
Guy Joos
Romain Pauwels
Guy Brusselle
A1
Journal Article
in
THORAX
2006
Medication use and disease control of asthmatic patients in Flanders: A cross-sectional community pharmacy study
Els Mehuys
Lucas Van Bortel
Lieven Annemans
Jean Paul Remon
Inge Van Tongelen
E VAN GANSE
L LAFOREST
G CHAMBA
Guy Brusselle
A1
Journal Article
in
RESPIRATORY MEDICINE
2006
Murine TLR4 is implicated in cigarette smoke-induced pulmonary inflammation
Tania Maes
Ken Bracke
Karim Vermaelen
Ingel Demedts
Guy Joos
Romain Pauwels
Guy Brusselle
A1
Journal Article
in
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
2006
Murine models of COPD
Guy Brusselle
Ken Bracke
Tania Maes
An D'hulst
Katrien Moerloose
Guy Joos
Romain Pauwels
A1
Journal Article
in
PULMONARY PHARMACOLOGY & THERAPEUTICS
2006
Mycobacterium avium complex with a distinct clinical and iconographic presentation: The lady Windermere syndrome
H GOEMINNE
Renaat Peleman
Guy Brusselle
Kurt Tournoy
A1
Journal Article
in
ACTA CLINICA BELGICA
2006
Observational study on respiratory symptoms and household cleaning activities in female workers
Inge Gevaert
Philippe Kiss
Marc De Meester
Guy Brusselle
C3
Conference
2006
Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema
Ingel Demedts
Tine Demoor
Ken Bracke
Guy Joos
Guy Brusselle
A1
Journal Article
in
RESPIRATORY RESEARCH
2006
Role of tumour necrosis factor-alpha receptor p75 in cigarette smoke-induced pulmonary inflammation and emphysema
An D'hulst
Ken Bracke
Tania Maes
Jan De Bleecker
Romain Pauwels
Guy Joos
Guy Brusselle
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2006
2005
Cigarette smoke-induced pulmonary emphysema in scid-mice. Is the acquired immune system required?
An D'hulst
Tania Maes
Ken Bracke
Ingel Demedts
Kurt Tournoy
Guy Joos
Guy Brusselle
A1
Journal Article
in
RESPIRATORY RESEARCH
2005
De vuurspuwerslong: een bijzondere casus van aspiratiepneumonitis
Fre Bauters
Kurt Tournoy
Robert Gosselin
Guy Brusselle
Guy Joos
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2005
Identification and characterization of human pulmonary dendritic cells
Ingel Demedts
Guy Brusselle
Karim Vermaelen
Romain Pauwels
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
2005
Matrix metalloproteinase-12 and cathepsin D expression in pulmonary macrophages and dendritic cells of cigarette smoke-exposed mice
Ken Bracke
D CATALDO
Tania Maes
M GUEDERS
A NOEL
JM FOIDART
Guy Brusselle
Romain Pauwels
A1
Journal Article
in
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
2005
Matrix metalloproteinases in asthma and COPD
Ingel Demedts
Guy Brusselle
Ken Bracke
Karim Vermaelen
Romain Pauwels
A1
Journal Article
in
CURRENT OPINION IN PHARMACOLOGY
2005
Positioning of glucocorticosteroids in asthma and allergic rhinitis guidelines (versus other therapies)
Guy Joos
Guy Brusselle
Helen Van Hoecke
Paul Van Cauwenberge
Jean Bousquet
Romain A Pauwels
A1
Journal Article
in
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
2005
Time course of cigarette smoke-induced pulmonary inflammation in mice
AI D'HULST
KY VERMAELEN
Guy Brusselle
Guy Joos
Romain Pauwels
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2005
2003
Tiotropium bromide : a long-acting anticholinergic bronchodilator for the treatment of patients with chronic obstructive pulmonary disease
Guy Joos
Guy Brusselle
Eric Derom
Romain Pauwels
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
2003
2000
Interleukin 5 regulates the isoform expression of its own receptor alpha-subunit.
Jan Tavernier
J VAN DER HEYDEN
A VERHEE
Guy Brusselle
Xaveer Van Ostade
Joël Vandekerckhove
J NORTH
SM RANKIN
AB KAY
DS ROBINSON
A1
Journal Article
in
BLOOD
2000
1998
Cytokines and their receptors as therapeutic targets in asthma
Romain Pauwels
Guy Brusselle
Kurt Tournoy
Bart Lambrecht
Johan Kips
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
1998
1997
Cytokine manipulation in animal models of asthma.
Romain Pauwels
Guy Brusselle
Johan Kips
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
1997
Role of IFN-gamma in the inhibition of the allergic airway inflammation caused by IL-12.
Guy Brusselle
Johan Kips
Renaat Peleman
Guy Joos
RR DEVOS
Jan Tavernier
Romain Pauwels
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
1997
Serum neuron-specific enolase as a tumor marker in the diagnosis and follow-up of small-cell lung cancer.
Philippe Pinson
Guy Joos
Patrick Watripont
Guy Brusselle
Romain Pauwels
A1
Journal Article
in
RESPIRATION
1997
1996
Interleukin-12 inhibits antigen-induced airway hyperresponsiveness in mice.
Johan Kips
Guy Brusselle
Guy Joos
Renaat Peleman
Jan Tavernier
RR DEVOS
Romain Pauwels
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
1996
1995
Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-defïcient mice.
Guy Brusselle
Johan Kips
Guy Joos
H BLUETHMANN
Romain Pauwels
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
1995
Importance of interleukin-4 and interleukin-12 in allergen-induced airway changes in mice.
Johan Kips
Guy Brusselle
Guy Joos
Renaat Peleman
RR DEVOS
Jan Tavernier
Romain Pauwels
A1
Journal Article
in
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
1995
Inhibition of the allergen induced eosinophil influx in murine airways by EL-12 is not mediated through IFN-gamma
J KIPS
Guy Brusselle
Renaat Peleman
Guy Joos
Romain Pauwels
A2
Journal Article
in
American Journal Resp. Critical Care Medicine, 151, A826, 1 tab
1995
1994
ATTENUATION OF ALLERGIC AIRWAY INFLAMMATION IN IL-4 DEFICIENT MICE.
Guy Brusselle
Johan Kips
Jan Tavernier
JG VANDERHEYDEN
Claude Cuvelier
Romain Pauwels
H BLUETHMANN
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
1994
An in vivo mouse model of allergic airway inflammation and airway hyperresponsiveness
Guy Brusselle
J KIPS
Renaat Peleman
Guy Joos
Romain Pauwels
A2
Journal Article
in
American Journal Resp. Crit. Care Med., 149, nr. 4, p. A754, 1 tab
1994
Immune responses in Interleukin 4-deficient mice
Guy Brusselle
GLE Gros
G Kohler
N Schultze
P Köbel
Johan Kips
Romain Pauwels
H Blüthmann
Bookchapter
in
Transgenesis and targeted mutagenesis for immune system analysis
1994
Interleukin-12 inhibits allergen induced airway inflammation and hyperresponsiveness in mice
Johan Kips
Guy Brusselle
Renaat Peleman
Guy Joos
J TAVERNIER
M GATELY
Romain Pauwels
A2
Journal Article
in
American Journal Resp. Crit. Care Med., New York, 149, nr. 4, p. A754, 1 tab
1994
1992
Organization and chromosomal localization of the human interleukin 5 receptor cc-chain gene
T Tuypens
G Plaetinck
E Baker
G Sutherland
Guy Brusselle
Walter Fiers
R Devos
Jan Tavernier
A2
Journal Article
in
EUROPEAN CYTOKINE NETWORK
1992