Research Explorer

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Researcher

Griet Glorieux

Publications & Research Data

Awards & Distinctions

305 Results

2026

A guide to uraemic toxicity

Griet GlorieuxStephane BurteyPieter EvenepoelJoachim JankowskiLaetitia KoppeRosalinde MasereeuwRaymond Vanholder

A1 Journal Article in NATURE REVIEWS NEPHROLOGY

Host factors dictate gut microbiome alterations in chronic kidney disease more strongly than kidney function

H. KrukowskiSophie ValkenburgA. Vich VilaL. F. MacielJ. F. Vázquez-CastellanosTessa GrypMarie JoossensWim Van BiesenFrancis VerbekeM. Derrien et al.

A1 Journal Article in NATURE MICROBIOLOGY

Kidney function modulates gut microbial metabolism

Mara LauriolaSophie ValkenburgSander DejonghWard ZadoraHubert KrukowskiPieter EvenepoelJeroen RaesRicard FarréGriet GlorieuxBjörn Meijers

A1 Journal Article in TOXINS

Link between intestinally generated uraemic metabolites and the gut microbiome in chronic kidney disease

Sophie ValkenburgGriet GlorieuxFrancis Verbeke

Predicting dialyzer fiber blocking is hard due to high intrapatient variability and limited utility of thrombin generation markers

Sunny ElootTom MertensIván JosipovicJoke KoningsGriet GlorieuxLaura E. FredenburghMark RoestRolando AcostaFilip De SomerEthan P. Marin et al.

A1 Journal Article in SCIENTIFIC REPORTS

2025

A mutant zebrafish model in the search for new therapies for childhood chronic kidney disease

Pauline Van WesemaelJolien De VelderGriet GlorieuxSophie LobbestaelMarina HorvatPatrick SipsEvelien Snauwaert

A randomised cross-over trial of pre- vs post-dilution haemodiafiltration in children on maintenance dialysis : effect on inflammation and nutrition markers

Ayse AgbasNur CanpolatBruno RanchinClaus SchmittSacha FlammierMiriam SchwetlickLynsey StronachKate WalkerKathryn WatersSeha Saygili et al.

A specifically designed multi-biotic reduces uremic toxin generation and improves kidney function

Alice BeauJane NatividadBerengère BenoitPhilippe DeleriveStéphane DubouxYuan FengMarie JammesCecile BarnelGiuseppina SequinoClaudie Pinteur et al.

A1 Journal Article in GUT MICROBES

Assessment of within- and inter-patient variability of uremic toxin concentrations in children with CKD

Evelien SnauwaertStefanie De BuyserAn DesloovereWim Van BiesenAnn RaesGriet GlorieuxLaure CollardKoen Van HoeckMaria Van DyckNathalie Godefroid et al.

Home-based exercise and physical activity intervention after kidney transplantation : impact of exercise intensity (PHOENIX-Kidney) : protocol for a multicentre randomized controlled trial

Stefan De SmetMarieke VandecruysJasmine De BeirSofie LeunisKarsten Vanden WyngaertMarie RenierHenriette De LoorKaatje GoetschalckxMaarten NaesensDelphine De Smedt et al.

A1 Journal Article in CLINICAL KIDNEY JOURNAL

In silico prediction of optimal multifactorial intervention in chronic kidney disease

Agnieszka LatosinskaIoanna K. MinaThi Minh Nghia NguyenIgor GolovkoFelix KellerGert MayerPeter RossingJan A. StaessenChristian DellesJoachim Beige et al.

A1 Journal Article in JOURNAL OF TRANSLATIONAL MEDICINE

Indoxyl sulfate contributes to impaired height velocity in (pre-)school children

Evelien SnauwaertStefanie De BuyserWim Van BiesenAnn RaesGriet GlorieuxLaure CollardKoen Van HoeckMaria Van DyckNathalie GodefroidJohan Vande Walle et al.

Lymphocyte phenotypes and protein-bound uremic toxins as determinants of clinical outcomes in hemodialysis patients

Theodoros TourountzisGeorgios LiouliosStamatia StaiSteven Van LaeckeEleni MoysidouMichalis ChristodoulouAriadni FouzaAsimina FylaktouKonstantia KantartziGriet Glorieux et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Medium chain fatty acids are potent binding competitors to improve protein-bound uremic toxin clearance during hemodialysis

Laure-Anne RaillonNans FlorensFlorine PayelleMarie MartinLaurent SoulèreDan YiZoé Simon-OnfroyStéphane ChambertMarie LegrasLaurence Chardon et al.

A1 Journal Article in KIDNEY INTERNATIONAL

Metabolomics to identify unclassified uremic toxins : a comprehensive literature review

Raymond VanholderGriet GlorieuxAngel ArgilesStephane BurteyGerald CohenFlore DurantonLaetitia KoppeZiad A. MassyAlberto OrtizRosalinde Masereeuw et al.

A2 Journal Article in KIDNEY MEDICINE

Multi-disciplinary and omics-driven approaches to advance personalized medicine in cardiovascular and chronic kidney disease

Griet GlorieuxJulie KleinAgnieszka Latosinska

Editorial material

Randomized cross-over study to examine associations between dialyzer clotting, uremic toxin removal, and hemocompatibility during post-dilution hemodiafiltration with reduced anticoagulation

Sunny ElootAnsgar ErlenkotterAdam M. ZawadaIván JosipovicAlfred GagelWim Van BiesenFilip De SomerGriet GlorieuxKatrien DevreeseMatthieu Boone et al.

A1 Journal Article in ARTIFICIAL ORGANS

Terminally differentiated effector memory T cells in kidney transplant recipients : new crossroads

Steven Van LaeckeGriet Glorieux

A1 Journal Article in AMERICAN JOURNAL OF TRANSPLANTATION

The effect of ß-glucan prebiotic on kidney function, uremic toxins and gut microbiome in stage 3 to 5 chronic kidney disease (CKD) predialysis participants : a randomized controlled trial (vol 14, 805, 2022)

Zarina EbrahimSebastian ProostRaul Yhossef TitoJeroen RaesGriet GlorieuxMohammed Rafique MoosaRenee Blaauw

The omics-driven machine learning path to cost-effective precision medicine in chronic kidney disease

M LopesR Colettif DurantonGriet GlorieuxMA Jaimes CamposJulie KleinM LeyP PercoA SampriA Tur-Sinai

A1 Journal Article in PROTEOMICS

Time-averaged concentration estimation of uraemic toxins with different removal kinetics : a novel approach based on intradialytic spent dialysate measurements (vol 16, pg 735, 2023)

Joosep PaatsAnnika AdobergJurgen ArundAnnemieke DhondtAnders FernstromIvo FridolinGriet GlorieuxEmilio Gonzalez-ParraJana HolmarLiisi Leis et al.

Toxic microbiome and progression of chronic kidney disease : insights from a longitudinal CKD-microbiome study

Manolo LaiolaLaetitia KoppeAmine LarabiFlorence ThirionCeline LangeBenoit QuinquisAymeric DavidEmmanuelle Le ChatelierBerengere BenoitGiuseppina Sequino et al.

A1 Journal Article in GUT

Uremic toxins levels are associated with miR-223 in chronic kidney disease-associated anemia

Emma BrisotPierre-Marie LepretreEya HamzaOphelie FourdinierBenjamin BrigantHakim Ouled-HaddouGabriel ChoukrounZiad A. MassyFrancis VerbekeValerie Metzinger-Le Meuth et al.

A2 Journal Article in NON-CODING RNA RESEARCH

2024

Assessment of within- and inter-patient variability of uremic toxin concentrations in children with CKD

Evelien SnauwaertStefanie De BuyserAn DesloovereWim Van BiesenAnn RaesGriet GlorieuxLaure CollardKoen Van HoeckMaria Van DyckNathalie Godefroid et al.

A1 Journal Article in TOXINS

Association of uremic toxins with morbidity and mortality in patients on hemodialysis

Theodoros TourountzisGeorgios LiouliosSteven Van LaeckeStamatia StaiMichalis ChristodoulouEleni MoysidouAsimina FylaktouGriet GlorieuxMaria Stangou

Dialysis patients survival in HD centres from Belgium, Estonia, Spain, and Sweden-association with BMI and hypocalcemia

Jana HolmarMerike LumanAnnika AdobergLiisi LeisJoosep PaatsFredrik UhlinAlberto OrtizGriet GlorieuxAnnemieke DhondtKristjan Pilt et al.

Future of uremic toxin management

Raymond VanholderEvelien SnauwaertFrancis VerbekeGriet Glorieux

A1 Journal Article in TOXINS

Indoxyl sulfate contributes to impaired height velocity in (pre)school children

Evelien SnauwaertStefanie De BuyserWim Van BiesenAnn RaesGriet GlorieuxLaure CollardKoen Van HoeckMaria Van DyckNathalie GodefroidJohan Vande Walle et al.

A1 Journal Article in KIDNEY INTERNATIONAL REPORTS

Integration of urinary peptidome and fecal microbiome to explore patient clustering in chronic kidney disease

Emmanouil MavrogeorgisSophie ValkenburgJustyna SiwyAgnieszka LatosinskaGriet GlorieuxHarald MischakJoachim Jankowski

A2 Journal Article in PROTEOMES

Investigation of the human-gut-kidney axis by fecal proteomics, highlights molecular mechanisms affected in CKD

Sonnal LohiaSophie ValkenburgRafael StroggilosVasiliki LygirouManousos MakridakisJerome ZoidakisFrancis VerbekeGriet GlorieuxAntonia Vlahou

A1 Journal Article in HELIYON

Revitalizing the gut microbiome in chronic kidney disease : a comprehensive exploration of the therapeutic potential of physical activity

Marieke VandecruysStefan De SmetJasmine De BeirMarie RenierSofie LeunisHanne Van CriekingeGriet GlorieuxJeroen RaesKarsten Vanden WyngaertEvi Nagler et al.

A1 Journal Article in TOXINS

2023

Calprotectin is a contributor to and potential therapeutic target for vascular calcification in chronic kidney disease

Ana Amaya-GarridoManon BrunetBenedicte Buffin-MeyerAlexis PiedrafitaLucile GrzesiakEzechiel AgbegboArnaud Del BelloInes FerrandizSerban ArdeleanuMarcelino Bermudez-Lopez et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

Glycosylation analysis of urinary peptidome highlights IGF2 glycopeptides in association with CKD

Sonnal LohiaAgnieszka LatosinskaJerome ZoidakisManousos MakridakisHarald MischakGriet GlorieuxAntonia VlahouVera Jankowski

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut microbiome studies in CKD : opportunities, pitfalls and therapeutic potential

Hubert KrukowskiSophie ValkenburgAvra-Melina MadellaJohan GarssenJeroen van BergenhenegouwenSaskia Adriana OverbeekGeert R. B. HuysJeroen RaesGriet Glorieux

A1 Journal Article in NATURE REVIEWS NEPHROLOGY

Identification of glycosylated IGF2 in human urinary peptidome and its association with CKD

Sonnal LohiaAgnieszka LatosinskaJerome ZoidakisManousos MakridakisHarald MischakGriet GlorieuxAntonia VlahouVera Jankowski

Immunosenescence and immune exhaustion are associated with levels of protein-bound uremic toxins in patients on hemodialysis

Theodoros TourountzisGeorgios LiouliosSteven Van LaeckeEvdoxia GinikopoulouVasiliki NikolaidouEleni MoysidouStamatia StaiMichalis ChristodoulouAsimina FylaktouGriet Glorieux et al.

A1 Journal Article in BIOMEDICINES

Impact of symbiotics on uremic toxins production, renal function and pew syndrome in shime and CKD mice models

Alice BeauBerengere BenoitMarie JammesClaudie PinteurDenis FouqueGriet GlorieuxHubert VidalJane NatividadLaetitia Koppe

Machine learning-based urine peptidome analysis to predict and understand mechanisms of progression to kidney failure

Ziad A. MassyOriane LambertMarie MetzgerMohammed SedkiAdeline ChaubetBenjamin BreuilAcil JaafarIvan TackThao Nguyen-KhoaMelinda Alves et al.

A1 Journal Article in KIDNEY INTERNATIONAL REPORTS

Modulation of blood pressure through microbiome exchange between milan normotensive and hypertensive strains of rats

Yoko SuzumotoAbbas ShamsLuciano D'apolitoConsiglia LongobardiFrancesco TrepiccioneCristoforo SilvestriGriet GlorieuxVincenzo Di MarzoGiovambattista Capasso

Predictive value of protein-bound uremic toxins for heart failure events in patients with chronic kidney disease

Bert ZwaenepoelTine De BackerWim Van BiesenGriet GlorieuxFrancis Verbeke

Prognosis and personalized in silico prediction of treatment efficacy in cardiovascular and chronic kidney disease : a proof-of-concept study

Mayra Alejandra Jaimes CamposIvan AndujarFelix KellerGert MayerPeter RossingJan A. StaessenChristian DellesJoachim BeigeGriet GlorieuxAndrew L. Clark et al.

A1 Journal Article in PHARMACEUTICALS

Role of the microbiome in gut-heart-kidney cross talk

Griet GlorieuxSanjay K. NigamRaymond VanholderFrancis Verbeke

A1 Journal Article in CIRCULATION RESEARCH

Time-averaged concentration estimation of uraemic toxins with different removal kinetics : a novel approach based on intradialytic spent dialysate measurements

Joosep PaatsAnnika AdobergJürgen ArundAnnemieke DhondtAnders FernströmIIvo FridolinGriet GlorieuxEmilio Gonzalez-ParraJana HolmarLiisi Leis et al.

A1 Journal Article in CLINICAL KIDNEY JOURNAL

Uremic toxins are associated with immune-senescence and immune-exhaustion in hemodialysis patients

Theodoros TourountzisGeorgios LiouliosSteven Van LaeckeMichalis ChristodoulouEleni MoysidouStamatia StaiAsimina FylaktouGriet GlorieuxMaria Stangou

2022

A home-based exercise and physical activity intervention after kidney transplantation : impact of exercise intensity : the Phoenix-kidney study protocol

Marieke VandecruysStefan De SmetVéronique CornelissenJeroen RaesSabina De GeestMaarten NaesensSofie LeunisJasmine De BeirKarsten Vanden WyngaertEvi Nagler et al.

Contribution of hypoalbuminemia and anemia to the prognostic value of plasma p-cresyl sulfate and p-cresyl glucuronide for cardiovascular outcome in chronic kidney disease

Francis VerbekeRaymond VanholderWim Van BiesenGriet Glorieux

A1 Journal Article in JOURNAL OF PERSONALIZED MEDICINE

Dietary advanced glycation end products in an elderly population with diabetic nephropathy : an exploratory investigation

Mieke SteenbekeIgnace De DeckerSophie MarchandGriet GlorieuxWim Van BiesenBruno LapauwJoris DelangheMarijn Speeckaert

A1 Journal Article in NUTRIENTS

Effect of simplified dietary advice on nutritional status and uremic toxins in chronic kidney disease participants

Zarina EbrahimGriet GlorieuxM. Rafique MoosaRenee Blaauw

A2 Journal Article in SOUTH AFRICAN JOURNAL OF CLINICAL NUTRITION

Potassium and fiber : a controversial couple in the nutritional management of children with chronic kidney disease

Amina El AmouriKato DelvaAurélie FoulonCharlotte Vande MoortelKoen Van HoeckGriet GlorieuxWim Van BiesenJohan Vande WalleAnn RaesEvelien Snauwaert et al.

A1 Journal Article in PEDIATRIC NEPHROLOGY

The effect of ss-glucan prebiotic on kidney function, uremic toxins and gut microbiome in stage 3 to 5 chronic kidney disease (CKD) predialysis participants : a randomized controlled trial

Zarina EbrahimSebastian ProostRaul Yhossef TitoJeroen RaesGriet GlorieuxMohammed Rafique MoosaRenee Blaauw

A1 Journal Article in NUTRIENTS

The role of advanced glycation end products and its soluble receptor in kidney diseases

Mieke SteenbekeReinhart SpeeckaertStéphanie DesmedtGriet GlorieuxJoris DelangheMarijn Speeckaert

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Treatment with paracetamol can interfere with the intradialytic optical estimation in spent dialysate of uric acid but not of indoxyl sulfate

Annika AdobergJoosep PaatsJurgen ArundAnnemieke DhondtIvo FridolinGriet GlorieuxJana HolmarKai LauriLiisi LeisMerike Luman et al.

A1 Journal Article in TOXINS

What if not all metabolites from the uremic toxin generating pathways are toxic? A hypothesis

Raymond VanholderSanjay K. NigamStephane BurteyGriet Glorieux

A1 Journal Article in TOXINS

2021

A low aromatic amino-acid diet improves renal function and prevent kidney fibrosis in mice with chronic kidney disease

Christophe BarbaBerengere BenoitEmilie BresStephanie ChanonAurelie Vieille-MarchisetClaudie PinteurSandra PesentiGriet GlorieuxCecile PicardDenis Fouque et al.

A1 Journal Article in SCIENTIFIC REPORTS

Association between carbamylated albumin, gut microbiota and their derived metabolites in chronic kidney disease

Mieke SteenbekeSophie ValkenburgWim Van BiesenJoris DelangheMarijn SpeeckaertGriet Glorieux

Data sharing under the General Data Protection Regulation : time to harmonize law and research ethics?

Antonia VlahouDara HallinanRolf ApweilerAngel ArgilesJoachim BeigeAriela BenigniRainer BischoffPeter C. BlackFranziska BoehmJocelyn Ceraline et al.

A1 Journal Article in HYPERTENSION

Dietary fiber intake and gut-derived uraemic toxins in a Belgian paediatric CKD cohort

Amina El AmouriEvelien SnauwaertAn DesloovereAurélie FoulonCharlotte Vande MoortelGriet GlorieuxWim Van BiesenJohan Vande WalleSunny ElootAnn Raes

Dietary fibre intake is associated with serum levels of uraemic toxins in children with chronic kidney disease

Amina El AmouriEvelien SnauwaertAurélie FoulonCharlotte Vande MoortelMaria Van DyckKoen Van HoeckNathalie GodefroidGriet GlorieuxWim Van BiesenJohan Vande Walle et al.

A1 Journal Article in TOXINS

Dietary fibre intake is low in paediatric chronic kidney disease patients but its impact on levels of gut-derived uraemic toxins remains uncertain

Amina El AmouriEvelien SnauwaertAurélie FoulonCharlotte Vande MoortelMaria Van DyckKoen Van HoeckNathalie GodefroidGriet GlorieuxWim Van BiesenJohan Vande Walle et al.

A1 Journal Article in PEDIATRIC NEPHROLOGY

Free p-cresyl sulfate shows the highest association with cardiovascular outcome in chronic kidney disease

Griet GlorieuxRaymond VanholderWim Van BiesenAnneleen PletinckEva SchepersNathalie NeirynckMarijn SpeeckaertDirk De BacquerFrancis Verbeke

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Gut microbiome profiling uncovers a lower abundance of Butyricicoccus in advanced stages of chronic kidney disease

Tessa GrypKaroline FaustWim Van BiesenGeert R. B. HuysFrancis VerbekeMarijn SpeeckaertJeroen RaesMario VaneechoutteMarie JoossensGriet Glorieux

A1 Journal Article in JOURNAL OF PERSONALIZED MEDICINE

Gut microbiota and their derived metabolites, a search for potential targets to limit accumulation of protein-bound uremic toxins in chronic kidney disease

Mieke SteenbekeSophie ValkenburgTessa GrypWim Van BiesenJoris DelangheMarijn SpeeckaertGriet Glorieux

A1 Journal Article in TOXINS

Measured glomerular filtration rate : the query for a workable golden standard technique

Marijn SpeeckaertJesse SeegmillerGriet GlorieuxNorbert LameireWim Van BiesenRaymond VanholderJoris Delanghe

A1 Journal Article in JOURNAL OF PERSONALIZED MEDICINE

Potassium and fibre : a controversial couple in the nutritional management of children with chronic kidney disease

Amina El AmouriKato DelvaAurélie FoulonCharlotte Vande MoortelKoen Van HoeckGriet GlorieuxWim Van BiesenJohan Vande WalleEvelien SnauwaertSunny Eloot et al.

Syndecan-1 and free indoxyl sulfate levels are associated with miR-126 in chronic kidney disease

O. FourdinierGriet GlorieuxB BirgantM DioefAnneleen PletinckRaymond VanholderG ChoukrounFrancis VerbekeZ.A MazzyV Metzinger-Le Meuth et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The impact of intradialytic cycling on the removal of protein-bound uraemic toxins : a randomised cross-over study

Celine De VosLaure LemarcqAnnemieke DhondtGriet GlorieuxWim Van BiesenSunny Eloot

A1 Journal Article in INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

The urinary proteomics classifier chronic kidney disease 273 predicts cardiovascular outcome in patients with chronic kidney disease

Francis VerbekeJustyna SiwyWim Van BiesenHarald MischakAnneleen PletinckEva SchepersNathalie NeirynckPedro MagalhãesMartin PejchinovskiClaudia Pontillo et al.

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Uremic toxins and cardiovascular system

Sophie ValkenburgGriet GlorieuxRaymond Vanholder

A1 Journal Article in CARDIOLOGY CLINICS

2020

A low aromatic amino-acid diet improves renal function and prevents kidney fibrosis in mice with chronic kidney disease

Christophe BarbaChristophe SoulageGriet GlorieuxCecile PicardDenis FouqueLaetitia Koppe

Carbamoylated nail proteins as assessed by near-infrared analysis are associated with load of uremic toxins and mortality in hemodialysis patients

Sander De BruyneJonas HimpeSigurd DelangheGriet GlorieuxWim Van BiesenMarc De BuyzereMarijn SpeeckaertJoris Delanghe

A1 Journal Article in TOXINS

Comparison of five assays for DNA extraction from bacterial cells in human faecal samples

Tessa GrypGriet GlorieuxMarie JoossensMario Vaneechoutte

A1 Journal Article in JOURNAL OF APPLIED MICROBIOLOGY

Difference in profiles of the gut-derived tryptophan metabolite indole acetic acid between transplanted and non-transplanted patients with chronic kidney disease

S LiabeufSM LavilleGriet GlorieuxL CheddaniF BrazierD Titeca BeauportRaymond VanholderG ChoukrounZA Massy

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of fecal microbiota transplantation on composition in mice with CKD.

C BarbaCO SoulageG CaggianoGriet GlorieuxD FouqueL Koppe

A1 Journal Article in TOXINS

Exploring the possibilities of infrared spectroscopy for urine sediment examination and detection of pathogenic bacteria in urinary tract infections

Mieke SteenbekeSander De BruyneJerina BoelensMatthijs OyaertGriet GlorieuxWim Van BiesenJere LinjalaJoris DelangheMarijn Speeckaert

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Gut microbiota generation of protein-bound uremic toxins and related metabolites is not altered at different stages of chronic kidney disease see

Tessa GrypKim De PaepeRaymond VanholderFrederiek-Maarten KerckhofWim Van BiesenTom Van de WieleFrancis VerbekeMarijn SpeeckaertMarie JoossensMarie Madeleine Couttenye et al.

A1 Journal Article in KIDNEY INTERNATIONAL

Gut-derived metabolites and their role in immune dysfunction in chronic kidney disease

Griet GlorieuxTessa GrypAlessandra Perna

A1 Journal Article in TOXINS

Haemodiafiltration does not lower protein-bound uraemic toxin levels compared with haemodialysis in a paediatric population

Evelien SnauwaertWim Van BiesenAnn RaesGriet GlorieuxJohan Vande WalleSanne RoelsRaymond VanholderVarvara AskitiKarolis AzukaitisAysun Bayazit et al.

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Health utility but not uremic toxins are associated with one year mortality in HD patients

Wim Van BiesenAmaryllis Van CraenenbroeckDaniel AbramowiczHolvoet ElsVeys NicGriet GlorieuxMarie Madeleine CouttenyeSunny Eloot

Identification and quantification of uremic toxin precursors-generating gut bacteria in chronic kidney disease

Tessa GrypMario VaneechoutteMarie JoossensWim Van BiesenGriet Glorieux

Isolation and quantification of uremic toxin precursor-generating gut bacteria in chronic kidney disease patients

Tessa GrypGeert R. B. HuysMarie JoossensWim Van BiesenGriet GlorieuxMario Vaneechoutte

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Review on uremic toxins : classification, concentration, and interindividual variability (vol 63, pg 1934, 2003)

Raymond VanholderRita De SmetGriet Glorieux

Serum levels and removal by haemodialysis and haemodiafiltration of tryptophan-derived uremic toxins in ESKD patients

J PaatsA AdobergJ ArundAnnemieke DhondtA FernströmI FridolinGriet GlorieuxL LeisM LumanE Gonzales-Parra et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Spot urine versus 24-hour urine collection for estimation of the generation of uremic toxins originating from gut microbial metabolism : reply

Tessa GrypRaymond VanholderGriet Glorieux

A1 Journal Article in KIDNEY INTERNATIONAL

The gut-kidney axis : colon-derived protein-bound uremic toxins in chronic kidney disease

Tessa GrypGriet GlorieuxMario VaneechoutteMarie Joossens

Uremic toxins promote accumulation of oxidized protein and increased sensitivity to hydrogen peroxide in endothelial cells by impairing the autophagic flux

S RodriguesS SantosT MeirelesN RomeroGriet GlorieuxR Pecoits-FilhoD ZhangL Nakao

A1 Journal Article in BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

UV fluorescence-based determination of urinary advanced glycation end products in patients with chronic kidney disease

Mieke SteenbekeSander De BruyneElisabeth Van AkenGriet GlorieuxWim Van BiesenJonas HimpeGilles De MeesterMarijn SpeeckaertJoris Delanghe

A1 Journal Article in DIAGNOSTICS

2019

An in-vitro assay using human spermatozoa to detect toxicity of biologically active substances

Tino VollmerBorje LjungbergVera JankowskiJoachim JankowskiGriet GlorieuxBernd G Stegmayr

A1 Journal Article in SCIENTIFIC REPORTS

Concentrations of p-cresyl - and indoxyl sulfate and their precursors in different stages of chronic kidney disease : from feces to urine

Tessa GrypKim De PaepeFrederiek-Maarten KerckhofWim Van BiesenRaymond VanholderMarie JoossensMario VaneechoutteGriet Glorieux

Contribution of the uremic milieu to an increased pro-inflammatory monocytic phenotype in chronic kidney disease

Natalia Borges BonanEva SchepersRoberto Pecoits-FilhoAnnemieke DhondtAnneleen PletinckFilip De SomerRaymond VanholderWim Van BiesenAndrea Moreno-AmaralGriet Glorieux

A1 Journal Article in SCIENTIFIC REPORTS

Evolution of protein-bound uremic toxins indoxyl sulphate and p-cresyl sulphate in acute kidney injury

Laurens VeldemanJill VanmassenhoveWim Van BiesenZiad A MassySophie LiabeufGriet GlorieuxRaymond Vanholder

A1 Journal Article in INTERNATIONAL UROLOGY AND NEPHROLOGY

Gut microbiota dynamics and uraemic toxins : one size does not fit all

Marie JoossensKaroline FaustTessa GrypAnh Thi Loan NguyenJun WangSunny ElootEva SchepersAnnemieke DhondtAnneleen PletinckSara Vieira-Silva et al.

A1 Journal Article in GUT

Selective transport of protein-bound uremic toxins in erythrocytes

Olivier DeltombeGriet GlorieuxSami MarzoukiRosalinde MasereeuwDaniel SchneditzSunny Eloot

A1 Journal Article in TOXINS

Serum levels of miR-126 and miR-223 and outcomes in chronic kidney disease patients

Ophélie FourdinierEva SchepersValérie Metzinger-Le MeuthGriet GlorieuxSophie LiabeufFrancis VerbekeRaymond VanholderBenjamin BrigantAnneleen PletinckMomar Diouf et al.

A1 Journal Article in SCIENTIFIC REPORTS

The role of the intestinal microbiota in uremic solute accumulation : a focus on sulfur compounds

Alessandra F PernaGriet GlorieuxMiriam ZacchiaFrancesco TrepiccioneGiovanna CapolongoCarmela VigoritoEvgeniya AnishchenkoDiego Ingrosso

A1 Journal Article in JOURNAL OF NEPHROLOGY

Uremic toxin concentrations are related to residual kidney function in the pediatric hemodialysis population

Evelien SnauwaertEls HolvoetWim Van BiesenAnn RaesGriet GlorieuxJohan Vande WalleSanne RoelsRaymond VanholderVarvara AskitiKarolis Azukaitis et al.

A1 Journal Article in TOXINS

Uremic toxin concentrations are related to residual kidney function in the pediatric hemodialysis population

Evelien SnauwaertAmina El AmouriEls HolvoetWim Van BiesenAnn RaesGriet GlorieuxJ. Van de WalleRaymond VanholderV. Askiti et al.

2018

A plea for more uremic toxin research in children with chronic kidney disease

Evelien SnauwaertWim Van BiesenAnn RaesGriet GlorieuxRaymond VanholderJohan Vande WalleSunny Eloot

Editorial material

Accumulation of uraemic toxins is reflected only partially by estimated GFR in paediatric patients with chronic kidney disease

Evelien SnauwaertWim Van BiesenAnn RaesEls HolvoetGriet GlorieuxKoen Van HoeckMaria Van DyckNathalie GodefroidRaymond VanholderSanne Roels et al.

A1 Journal Article in PEDIATRIC NEPHROLOGY

Assessment of the association between increasing membrane pore size and endotoxin permeability using a novel experimental dialysis simulation set-up

Eva SchepersGriet GlorieuxSunny ElootMichael HulkoAdriana Boschetti-de-FierroWerner BeckBernd KrauseWim Van Biesen

A1 Journal Article in BMC NEPHROLOGY

Association between protein-bound uremic toxins and asymptomatic cardiac dysfunction in patients with chronic kidney disease

Shanmugakumar ChinnappaYu-Kang TuYi Chun YehGriet GlorieuxRaymond VanholderAndrew Mooney

A1 Journal Article in TOXINS

Binding of bromocresol green and bromocresol purple to albumin in hemodialysis patients

Sigurd DelangheWim Van BiesenNadeige Van de VeldeSunny ElootAnneleen PletinckEva SchepersGriet GlorieuxJoris DelangheMarijn Speeckaert

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Biochemical and clinical impact of organic uremic retention solutes : a comprehensive update

Raymond VanholderAnneleen PletinckEva SchepersGriet Glorieux

A1 Journal Article in TOXINS

Concentrations of protein-bound uremic toxins in children on conventional HD are mainly affected by residual urine production

Evelien SnauwaertWim Van BiesenAnn RaesGriet GlorieuxJohan Vande WalleSanne RoelsKarolis AzukaitisAysun BayazitNur CampolatMichel Fischbach et al.

Concentrations of representative uraemic toxins in a healthy versus non-dialysis chronic kidney disease paediatric population

Evelien SnauwaertWim Van BiesenAnn RaesGriet GlorieuxVALERIE VAN BOGAERTKoen Van HoeckMarc CoppensSanne RoelsJohan Vande WalleSunny Eloot

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Deleting death and dialysis : conservative care of cardio-vascular risk and kidney function loss in chronic kidney disease (CKD)

Raymond VanholderSteven Van LaeckeGriet GlorieuxFrancis VerbekeEsmeralda Castillo-RodriguezAlberto Ortiz

A1 Journal Article in TOXINS

Early and asymptomatic cardiac dysfunction in chronic kidney disease

Shanmugakumar ChinnappaEdward ChiteNigel LewisOmer BaldoYu-Kang TuGriet GlorieuxRaymond VanholderMeguid El NahasAndrew Mooney

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Endothelial glycocalyx damage in CKD : role of the uremic toxin indoxyl sulfate

Anneleen PletinckEva SchepersWim Van BiesenGriet Glorieux

Gut-derived metabolites and chronic kidney disease : the forest (f)or the trees?

Raymond VanholderGriet Glorieux

Editorial material

Hereditary polycystic kidney disease is characterized by lymphopenia across all stages of kidney dysfunction : an observational study

Steven Van LaeckeTessa KerreEvi NaglerBart MaesRogier CaluweEva SchepersGriet GlorieuxWim Van BiesenFrancis Verbeke

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Increased urinary osmolyte excretion indicates chronic kidney disease severity and progression rate

Ryan B GilAlberto OrtizMaria D Sanchez-NiñoKaterina MarkoskaEva SchepersRaymond VanholderGriet GlorieuxPhilippe Schmitt-KopplinSilke S Heinzmann

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Residual urine production decreases concentrations of protein-bound uremic toxins more effectively than increased convection with hemodiafiltration

Evelien SnauwaertWim Van BiesenAnn RaesGriet GlorieuxJohan Vande WalleSanne RoelsKarolis AzukaitisAysun BayazitNur CanpolatMichel Fischbach et al.

Towards optimised dialysis removal of protein-bound uraemic toxins

Olivier DeltombeD SchneditzR MasereeuwGriet GlorieuxSunny Eloot

Urea and chronic kidney disease : the comeback of the century? (in uraemia research)

Raymond VanholderTessa GrypGriet Glorieux

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Uremic toxin accumulation pattern in pediatric maintenance HD : uremic toxins and comorbiditis

Evelien SnauwaertEls HolvoetWim Van BiesenAnn RaesGriet GlorieuxJohan Vande WalleSanne RoelsRaymond VanholderV AskitiK Azukaitis et al.

Value of urinary proteome-based classifier associated with chronic kidney disease and its progression in the prognosis of a patient-relevant endpoint, mortality

Justyna SiwyPedro MagalhaesEva SchepersClaudia PontilloAntonia VlahouGriet GlorieuxHarald Mischak

2017

An exploration of the association between uraemic toxin concentrations and quality of life in children with chronic kidney disease

Evelien SnauwaertElke De BruyneCharlotte Van HerzeeleEls HolvoetAnn RaesWim Van BiesenGriet GlorieuxKoen Van HoeckMaria Van DyckNathalie Godefroid et al.

An exploration of the association between uraemic toxin concentrations and quality of life in children with chronic kidney disease

Evelien SnauwaertElke De BruyneCharlotte Van HerzeeleEls HolvoetGriet GlorieuxKoen Van HoeckMaria Van DijckNathalie GodefroidAnn RaesSanne Roels et al.

Effect of sample temperature, pH, and matrix on the percentage protein binding of protein-bound uraemic toxins

Olivier DeltombeAnnemieke DhondtWim Van BiesenGriet GlorieuxSunny Eloot

A1 Journal Article in ANALYTICAL METHODS

Exploring binding characteristics and related competition of different uraemic toxins

Olivier DeltombeHenriette de LoorGriet GlorieuxAnnemieke DhondtWim Van BiesenBjörn MeijersSunny Eloot

Exploring binding characteristics and the related competition of different protein-bound uremic toxins

Olivier DeltombeHenriette de LoorGriet GlorieuxAnnemieke DhondtWim Van BiesenBjörn MeijersSunny Eloot

A1 Journal Article in BIOCHIMIE

Exploring protein binding of different uraeic toxins

Olivier DeltombeH de LoorGriet GlorieuxAnnemieke DhondtWim Van BiesenB MeijersSunny Eloot

Exploring protein binding of different uraemic toxins

Olivier DeltombeHenriette de LoorGriet GlorieuxAnnemieke DhondtWim Van BiesenBjörn MeijersSunny Eloot

Metabolic profiling of human plasma and urine in chronic kidney disease by hydrophilic interaction liquid chromatography coupled with time-of-flight mass spectrometry : a pilot study

Jente BoelaertFrederic LynenGriet GlorieuxEva SchepersNathalie NeirynckRaymond Vanholder

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Not creatinine but protein bound uraemic toxins are predominant in the prediction of QOL in children with CKD

Evelien SnauwaertE De BruyneCharlotte Van HerzeeleAnn RaesWim Van BiesenGriet GlorieuxK Van HoeckS RoelsJohan Vande WalleSunny Eloot

p-cresol sulfate and indoxyl sulfate: some clouds are gathering in the uremic toxin sky

Pieter EvenepoelGriet GlorieuxBjorn Meijers

Editorial material

p-Cresyl glucuronide is a major metabolite of p-cresol in mouse : in contrast to p-cresyl sulphate, p-cresyl glucuronide fails to promote insulin resistance

Laetitia KoppePascaline M AlixMarine L CrozeStéphane ChambertRaymond VanholderGriet GlorieuxDenis FouqueChristophe O Soulage

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

p-Cresyl sulfate

Tessa GrypRaymond VanholderMario VaneechoutteGriet Glorieux

A1 Journal Article in TOXINS

Prediction of chronic kidney disease stage 3 by CKD273, a urinary proteomic biomarker

Claudia PontilloZhen-Yu ZhangJoost P SchanstraLotte JacobsPetra ZürbigLutgarde ThijsAdela Ramirez-TorrezHiddo JL HeerspinkMorten LindhardtRonald Klein et al.

A1 Journal Article in KIDNEY INTERNATIONAL REPORTS

Quantification of carbamylated albumin in serum based on capillary electrophoresis

Sigurd DelangheAlena MoermanAnneleen PletinckEva SchepersGriet GlorieuxWim Van BiesenJoris DelangheMarijn Speeckaert

A1 Journal Article in ELECTROPHORESIS

Spontaneous variability of pre-dialysis concentrations of uremic toxins over time in stable hemodialysis patients

Sunny ElootWim Van BiesenSanne RoelsWillem DelrueEva SchepersAnnemieke DhondtRaymond VanholderGriet Glorieux

A1 Journal Article in PLOS ONE

The place of large pore membranes in the treatment portfolio of patients on hemodialysis

Wim Van BiesenRaymond VanholderEva SchepersGriet GlorieuxAnnemieke DhondtSunny Eloot

A1 Journal Article in Contributions to Nephrology

Uraemic toxin accumulation in paediatric CKD patients is only partially reflected by estimated GFR

Evelien SnauwaertWim Van BiesenAnn RaesEls HolvoetGriet GlorieuxKoen Van HoeckMaria Van DijckNathalie GodefroidSanne RoelsJohan Vande Walle et al.

2016

Association of advanced age with concentrations of uraemic toxins in CKD

Merita RrojiSunny ElootAnnemieke DhondtWim Van BiesenGriet GlorieuxNathalie NeirynckNele Van Den NoortgateS LiabeufZiad MassyRaymond Vanholder

A1 Journal Article in JOURNAL OF NEPHROLOGY

Clinical management of the uraemic syndrome in chronic kidney disease

Raymond VanholderDenis FouqueGriet GlorieuxGunnar H HeineMehmet KanbayFrancesca MallamaciZiad A MassyAlberto OrtizPatrick RossignolAndrzej Wiecek et al.

A1 Journal Article in LANCET DIABETES & ENDOCRINOLOGY

Concentrations of representative uremic toxins in a healthy versus uremic pediatric population

Evelien SnauwaertVALERIE VAN BOGAERTGriet GlorieuxWim Van BiesenAnn RaesJohan Vande WalleSunny Eloot

Concentrations of representative uremic toxins in a healthy versus uremic pediatric population

Evelien SnauwaertGriet GlorieuxVALERIE VAN BOGAERTWim Van BiesenAnn RaesJohan Vande WalleSunny Eloot

Determination of asymmetric and symmetric dimethylarginine in serum from patients with chronic kidney disease: UPLC-MS/MS versus ELISA

Jente BoelaertEva SchepersGriet GlorieuxSunny ElootRaymond VanholderFrederic Lynen

A1 Journal Article in TOXINS

Development of a MALDI MS-based platform for early detection of acute kidney injury

Emma CarrickJill VanmassenhoveGriet GlorieuxJochen MetzgerMohammed DaknaMartin PejchinovskiVera JankowskiBahareh MansoorianHolger HusiWilliam Mullen et al.

A1 Journal Article in PROTEOMICS CLINICAL APPLICATIONS

Disruption, but not overexpression of urate oxidase alters susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice

Lisa ThyrionJeanelle PortelliRobrecht RaedtGriet GlorieuxLars Emil LarsenMathieu SprengersWouter Van LysebettensEvelien CarretteJean DelbekeKristl Vonck et al.

A1 Journal Article in EPILEPSIA

Estimated GFR poorly reflects the concentration of various uremic toxins in pediatric CKD patients

Evelien SnauwaertGriet GlorieuxWim Van BiesenAnn RaesJohan Vande WalleSunny Eloot

Estimated GFR poorly reflects the concentration of various uremic toxins in pediatric CKD patients

Evelien SnauwaertGriet GlorieuxWim Van BiesenAnn RaesJohan Vande WalleSunny Eloot

Estimated GFR poorly relfects the concentration of various uremic toxins in pediatric CKD patients

Evelien SnauwaertGriet GlorieuxWim Van BiesenAnn RaesJohan Vande Walle

Future avenues to decrease uremic toxin concentration

Raymond VanholderSunny ElootGriet Glorieux

A1 Journal Article in AMERICAN JOURNAL OF KIDNEY DISEASES

Intestinal metabolites, chronic kidney disease and renal transplantation : Enigma Variations?

Raymond VanholderGriet GlorieuxZiad A Massy

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Levels of indoxyl sulfate in kidney transplant patients, and the relationship with hard outcomes

Sophie LiabeufLucie DesjardinsZiad A MassyFrançois BrazierPierre François WesteelHakim MazouzDimitri Titeca-BeauportMomar DioufGriet GlorieuxRaymond Vanholder et al.

A1 Journal Article in CIRCULATION JOURNAL

New low-flux mixed matrix membranes that offer superior removal of protein-bound toxins from human plasma

Denys PavlenkoEsmée van GeffenMies J van SteenbergenGriet GlorieuxRaymond VanholderKarin GF GerritsenDimitrios Stamatialis

A1 Journal Article in SCIENTIFIC REPORTS

Possible role of microRNAs in CKD progression

Theofilos PapadopoulosDaniel BorrasEric NeauSzymon FilipKaterina MarkoskaGoce SpasovskiGriet GlorieuxRaymond VanholderBart JanssenAntonia Vlahou et al.

Protein-bound uremic toxin profiling as a tool to optimize hemodialysis

Sunny ElootDaniel SchneditzTom CornelisWim Van BiesenGriet GlorieuxAnnemieke DhondtJeroen KoomanRaymond Vanholder

A1 Journal Article in PLOS ONE

Response to Tsikas et al. comments on Boelaert et al. Determination of asymmetric and symmetric dimethylarginine in serum from patients with chronic kidney disease: UPLC-MS/MS versus ELISA. Toxins 2016, 8, 149

Jente BoelaertEva SchepersGriet GlorieuxSunny ElootRaymond VanholderFrederic Lynen

Editorial material

Uric acid is released in the brain during seizure activity and increases severity of seizures in a mouse model for acute limbic seizures

Lisa ThyrionRobrecht RaedtJeanelle PortelliPieter Van LooWytse WadmanGriet GlorieuxBart LambrechtSophie JanssensKristl VonckPaul Boon

A1 Journal Article in EXPERIMENTAL NEUROLOGY

Urinary proteomics analysis reveals multiple features associated with chronic kidney disease progression

Szymon FilipGriet GlorieuxKaterina MarkoskaGiorgos MermelekasMagdalena KrochmalWilliam MullenJerome ZoidakisJoachim JankowskiGoce SpasovskiRaymond Vanholder et al.

2015

Chronic kidney disease and fibrosis : the role of uremic retention solutes

Henricus AM MutsaersElisabeth GD StribosGriet GlorieuxRaymond VanholderPeter Olinga

A2 Journal Article in FRONTIERS IN MEDICINE

Development and validation of an ultra-high performance liquid chromatography-tandem mass spectrometry method to measure creatinine in human urine

S FraselleK De CremerW CouckeGriet GlorieuxJill VanmassenhoveEva SchepersNathalie NeirynckI Van OvermeireJ Van LocoWim Van Biesen et al.

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Exploring mechanisms of protein binding of uraemic toxins in CKD2-5 and haemodialysis patients

Olivier DeltombeAnnemieke DhondtGriet GlorieuxWim Van BiesenSunny Eloot

Exploring protein binding of uraemic toxins in chronic kidney disease and haemodialysis patients

Olivier DeltombeWim Van BiesenGriet GlorieuxZ MassyAnnemieke DhondtSunny Eloot

Exploring protein binding of uremic toxins in patients with different stages of chronic kidney disease and during hemodialysis

Olivier DeltombeWim Van BiesenGriet GlorieuxZiad MassyAnnemieke DhondtSunny Eloot

A1 Journal Article in TOXINS

High-resolution plasma proteome analysis identifies new changes in molecular mechanisms involved in chronic kidney disease

Griet GlorieuxWilliam MullenFlore DurantonSzymon FilipNathalie GayrardHolger HusiEva SchepersNathalie NeirynckJoost SchanstraAntonia Vlahou et al.

Influence of severity of illness on neutrophil gelatinase-associated lipocalin performance as a marker of acute kidney injury : a prospective cohort study of patients with sepsis

Jill VanmassenhoveGriet GlorieuxNorbert LameireEric HosteAnnemieke DhondtRaymond VanholderWim Van Biesen

A1 Journal Article in BMC NEPHROLOGY

Micro-inflammation and cardiovascular disease in chronic kidney disease: role of the uremic peptides

Nathalie NeirynckRaymond VanholderGriet Glorieux

New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis

Griet GlorieuxWilliam MullenFlore DurantonSzymon FilipNathalie GayrardHolger HusiEva SchepersNathalie NeirynckJoost P SchanstraJoachim Jankowski et al.

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

New methods and technologies for measuring uremic toxins and quantifying dialysis adequacy

Raymond VanholderJente BoelaertGriet GlorieuxSunny Eloot

A1 Journal Article in SEMINARS IN DIALYSIS

Once upon a time in dialysis: the last days of Kt/V?

Raymond VanholderGriet GlorieuxSunny Eloot

A1 Journal Article in KIDNEY INTERNATIONAL

Prediction of renal failure in sepsis patients by established CE-MS peptide marker panels

Jill VanmassenhoveWim Van BiesenGriet GlorieuxHarald MischakWilliam MullenRaymond VanholderJochen Metzger

Pro-inflammatory cytokines and leukocyte oxidative burst in chronic kidney disease: culprits or innocent bystanders?

Nathalie NeirynckGriet GlorieuxEva SchepersAnnemieke DhondtFrancis VerbekeRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Protein-bound solute removal during extended multipass versus standard hemodialysis

Sunny ElootWim Van BiesenMette AxelsenGriet GlorieuxRobert Smith PedersenJames Goya Heaf

A1 Journal Article in BMC NEPHROLOGY

Protein-bound uraemic toxins, dicarbonyl stress and advanced glycation end products in conventional and extended haemodialysis and haemodiafiltration

Tom CornelisSunny ElootRaymond VanholderGriet GlorieuxFrank M van der SandeJean L ScheijenKarel M LeunissenJeroen P KoomanCasper G Schalkwijk

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Soluble tumor necrosis factor receptor 1 and 2 predict outcomes in advanced chronic kidney disease : a prospective cohort study

Nathalie NeirynckGriet GlorieuxEva SchepersFrancis VerbekeRaymond Vanholder

A1 Journal Article in PLOS ONE

The intestine and the kidneys : a bad marriage can be hazardous

Raymond VanholderGriet Glorieux

A2 Journal Article in CLINICAL KIDNEY JOURNAL

Transcriptome analysis in patients with chronic kidney disease on hemodialysis disclosing a key role for CD16⁺CX3CR1⁺ monocytes

Eva SchepersErica HouthuysAnnemieke DhondtGRIMBERT DE MEYERNathalie NeirynckPascal BernaertRafael Van den BerghPeter BrouckaertRaymond VanholderGriet Glorieux

A1 Journal Article in PLOS ONE

Uraemic toxin concentration variability in HD patients: can we still rely on the results of cross-sectional studies?

Sunny ElootWillem DelrueWim Van BiesenAnnemieke DhondtGriet Glorieux

Uraemic toxins and new methods to control their accumulation : game changers for the concept of dialysis adequacy

Griet GlorieuxJames Tattersall

A2 Journal Article in CLINICAL KIDNEY JOURNAL

Urinary proteomics to decipher molecular pathophysiology of CKD progression

Szymon FilipKaterina MarkoskaGriet GlorieuxTheofilos PapadopoulosWilliam MullenJerome ZoidakisJoachim JankowskiJoost-Peter SchanstraRaymond VanholderGoce Spasovski et al.

Where and when to inject low molecular weight heparin in hemodiafiltration? : a cross over randomised trial

Annemieke DhondtRuben PauwelsKatrien DevreeseSunny ElootGriet GlorieuxRaymond Vanholder

A1 Journal Article in PLOS ONE

2014

AKI in early sepsis is a continuum from transient AKI without tubular damage over transient AKI with minor tubular damage to intrinsic AKI with severe tubular damage

Jill VanmassenhoveGriet GlorieuxEric HosteAnnemieke DhondtRaymond VanholderWim Van Biesen

A1 Journal Article in INTERNATIONAL UROLOGY AND NEPHROLOGY

Association between indoxyl sulfate and bone histomorphometry in pre-dialysis chronic kidney disease patients

Fellype Carvalho BarretoDaniela Veit BarretoMaria Eugênia Fernandes CanzianiCristianne TomiyamaAndrea HigaAnaïs MozarGriet GlorieuxRaymond VanholderZiad MassyAluizio Barbosa de Carvalho

A2 Journal Article in JORNAL BRASILEIRO DE NEFROLOGIA

Bedside monitoring of anticoagulation in chronic haemodialysis patients treated with tinzaparin

Ruben PauwelsKatrien DevreeseWim Van BiesenSunny ElootGriet GlorieuxRaymond VanholderAnnemieke Dhondt

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Elevated soluble tumor necrosis factor alpha receptor 1 and 2 concentrations in hemodialysis patients are not reflected by alterations in membrane expression

Nathalie NeirynckGriet GlorieuxEva SchepersAnnemieke DhondtRaymond Vanholder

Introduction: Uremic toxicity: state of the art 2014

Raymond VanholderGriet Glorieux

Editorial material

Looking beyond endotoxin: a comparative study of pyrogen retention by ultrafilters used for the preparation of sterile dialyis fluid

Griet GlorieuxMichael HulkoRose SpeidelKatrin BrodbeckBernd KrauseRaymond Vanholder

A1 Journal Article in SCIENTIFIC REPORTS

Metabolic profiling of human plasma and urine in chronic kidney disease by hydrophilic interaction liquid chromatography coupled with time-of-flight mass spectrometry: a pilot study

Jente BoelaertFrederic LynenGriet GlorieuxEva SchepersNathalie NeirynckRaymond Vanholder

p-Cresyl sulphate has pro-inflammatory and cytotoxic actions on human proximal tubular epithelial cells

Jonay PovedaMaria D Sanchez-NiñoGriet GlorieuxAna B SanzJesús EgidoRaymond VanholderAlberto Ortiz

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

State-of-the-art non-targeted metabolomics in the study of chronic kidney disease

Jente BoelaertRuben t'KindtEva SchepersLucie JorgeGriet GlorieuxNathalie NeirynckFrederic LynenPatrick SandraRaymond VanholderKoen Sandra

A1 Journal Article in METABOLOMICS

The uremic toxicity of indoxyl sulfate and p-cresyl sulfate: a systematic review

Raymond VanholderEva SchepersAnneleen PletinckEvi NaglerGriet Glorieux

A1 Journal Article in JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

2013

A novel UPLC–MS–MS method for simultaneous determination of seven uremic retention toxins with cardiovascular relevance in chronic kidney disease patients

Jente BoelaertFrederic LynenGriet GlorieuxSunny ElootMaria Van LandschootMARIA WATERLOOSPatrick SandraRaymond Vanholder

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A pro-inflammatory change in numbers of monocyte and dendritic cell subtypes occurs early in the course of CKD

Eva SchepersGriet GlorieuxTim Van den AbeeleNathalie NeirynckRaymond Vanholder

An update on uremic toxins

Nathalie NeirynckRaymond VanholderEva SchepersSunny ElootAnneleen PletinckGriet Glorieux

A1 Journal Article in INTERNATIONAL UROLOGY AND NEPHROLOGY

Assesment of different cut-off levels of serum creatinine increase to predict mortality in septic patients

Jill VanmassenhoveEric HosteGriet GlorieuxAnnemieke DhondtRaymond VanholderWim Van Biesen

Determination of asymmetric and symmetric dimethylarginine in serum from patients with chronic kidney disease : UPLC-MS/MS versus ELISA

Jente BoelaertEva SchepersGriet GlorieuxRaymond VanholderFrederic Lynen

Does beta-2-microglobulin exert avascular damaging effect by activating leukocytes?

Nathalie NeirynckGriet GlorieuxJente BoelaertSophie LiabeufZiad MassyRaymond Vanholder

Does p-cresylglucuronide have the same impact on mortality as other protein-bound uremic toxins?

Sophie LiabeufGriet GlorieuxAurelie LengletMomar DioufEva SchepersLucie DesjardinsGabriel ChoukrounRaymond VanholderZiad A Massy

A1 Journal Article in PLOS ONE

Does the adequacy parameter Kt/V-urea reflect uremic toxin concentrations in hemodialysis patients?

Sunny ElootWim Van BiesenGriet GlorieuxNathalie NeirynckAnnemieke DhondtRaymond Vanholder

A1 Journal Article in PLOS ONE

LC- and GC-MS-based non-targeted metabolomics in the study of chronic kidney disease

Jente BoelaertRuben t'KindtLucie JorgeGriet GlorieuxEva SchepersNathalie NeirynckRaymond VanholderFrederic LynenPatrick SandraKoen Sandra

Looking further than endotoxin: a comparative study of pyrogen retention by ultrafilters applied for preparation of sterile dialysis fluid

Griet GlorieuxMichael HulkoRose SpeidelKatrin BrodbeckBernd KrauseRaymond Vanholder

Median term outcome of renal function in patients admitted to ICU with sepsis

Jill VanmassenhoveEric HosteGriet GlorieuxAnnemieke DhondtRaymond VanholderWim Van Biesen

Metabolic profiling by hydrophilic interaction ultra-performance liquid chromatography time-of-flight mass spectrometry in the study of chronic kidney disease

Jente BoelaertGriet GlorieuxEva SchepersNathalie NeirynckRaymond VanholderFrederic Lynen

Mixed matrix hollow fiber membranes for removal of protein-bound toxins from human plasma

Marlon SL TijinkMaarten WesterGriet GlorieuxKarin GF GerritsenJunfen SunPieter C SwartZandrie BornemanMatthias WesslingRaymond VanholderJaap A Joles et al.

A1 Journal Article in BIOMATERIALS

Non-targeted metabolomics in the study of chronic kidney disease

Jente BoelaertRuben t' KindtGriet GlorieuxEva SchepersLucie JorgeNathalie NeirynckFrederic LynenPatrick SandraKoen SandraRaymond Vanholder

p-Cresyl sulfate promotes insulin resistance associated with CKD

Laetitia KoppeNicolas J PillonRoxane E VellaMarine L CrozeCaroline C PelletierStephane ChambertZiad MassyGriet GlorieuxRaymond VanholderYann Dugenet et al.

A1 Journal Article in JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Predictors associated with short and median-term outcome of patients admitted to ICU with sepsis

Jill VanmassenhoveEric HosteGriet GlorieuxAnnemieke DhondtRaymond VanholderWim Van Biesen

Protein-bound uremic toxins stimulate crosstalk between leukocytes and vessel wall

Anneleen PletinckGriet GlorieuxEva SchepersGerald CohenBertrand GondouinMaria Van LandschootSunny ElootAngelique RopsJohan Van de VoordeAn De Vriese et al.

A1 Journal Article in JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Review of protein-bound toxins, possibility for blood purification therapy

Nathalie NeirynckGriet GlorieuxEva SchepersAnneleen PletinckAnnemieke DhondtRaymond Vanholder

A1 Journal Article in BLOOD PURIFICATION

The uraemic toxin indoxylsulfate induces leukocyte-endothelial adhesion and induces impaired blood flow in the rat peritoneal microcirculation

Anneleen PletinckGriet GlorieuxEva SchepersMaria Van LandschootSunny ElootWim Van BiesenRaymond Vanholder

Uremia-related oxidative stress in leukocytes is not triggered by β2-microglobulin

Nathalie NeirynckGriet GlorieuxJente BoelaertEva SchepersSophie LiabeufAnnemieke DhondtZiad MassyRaymond Vanholder

A1 Journal Article in JOURNAL OF RENAL NUTRITION

Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration

HAM MutsaersMJG WilmerD ReijndersJ JansenPHH van den BroekM ForkinkEva SchepersGriet GlorieuxRaymond VanholderLP van den Heuvel et al.

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Urinary output and fractional excretion of sodium and urea as indicators of transient versus intrinsic acute kidney injury during early sepsis

Jill VanmassenhoveGriet GlorieuxEric HosteAnnemieke DhondtRaymond VanholderWim Van Biesen

A1 Journal Article in CRITICAL CARE

2012

An obituary for GFR as the main marker for kidney function?

Raymond VanholderSunny ElootEva SchepersNathalie NeirynckGriet GlorieuxZiad Massy

A1 Journal Article in SEMINARS IN DIALYSIS

An update on protein-bound uremic retention solutes

Raymond VanholderEva SchepersAnneleen PletinckNathalie NeirynckGriet Glorieux

A1 Journal Article in JOURNAL OF RENAL NUTRITION

Classification and list of uremic toxins

Nathalie NeirynckRITA DE SMETEva SchepersRaymond VanholderGriet Glorieux

Bookchapter in Uremic toxins

Determination of seven uremic retention toxins in serum of chronic kidney disease patients by UPLC-MS/MS

Jente BoelaertFrederic LynenSunny ElootGriet GlorieuxMaria Van LandschootMARIA WATERLOOSRaymond Vanholder

Development of an UPLC-MS/MS method for the determination of seven uremic retention toxins in serum of chronic kidney disease patients

Jente BoelaertFrederic LynenSunny ElootGriet GlorieuxMaria Van LandschootMarie-Anne WaterloosRaymond Vanholder

Dialysis water and fluid purity: more than endotoxin

Griet GlorieuxNathalie NeirynckNic VeysRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Estimated glomerular filtration rate is a poor predictor of the concentration of middle molecular weight uremic solutes in chronic kidney disease

Nathalie NeirynckSunny ElootGriet GlorieuxDaniela V BarretoFellype C BarretoSophie LiabeufAurélie LengletHorst D LemkeZiad A MassyRaymond Vanholder

A1 Journal Article in PLOS ONE

Guanidino compounds

Sunny ElootGriet GlorieuxPeter Paul De DeynRaymond Vanholder

Bookchapter in Uremic toxins

In vivo effects of the protein-bound uremic toxins p-cresylsulfate, p-cresylglucuronide and indoxylsulfate on the cross-talk between leukocytes and the vessel wall

Anneleen PletinckGriet GlorieuxEva SchepersMaria Van LandschootJohan Van de VoordeWim Van BiesenRaymond Vanholder

KT/V is a poor predictor of concentration of a broad range of uremic toxins

Sunny ElootGriet GlorieuxNathalie NeirynckRaymond Vanholder

Novel method for simultaneous determination of p-cresylsulphate and p-cresylglucuronide: clinical data and pathophysiological implications

Natalie MeertEva SchepersGriet GlorieuxMaria Van LandschootJan GoemanMARIA WATERLOOSAnnemieke DhondtJohan Van der EyckenRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

p-Cresyl sulfate

Anneleen PletinckRaymond VanholderGriet Glorieux

Bookchapter in Uremic toxins

Plasma beta-2 microglobulin is associated with cardiovascular disease in uremic patients

Sophie LiabeufAurélie LengletLucie DesjardinsNathalie NeirynckGriet GlorieuxHorst-Dieter LemkeRaymond VanholderMomar DioufGabriel ChoukrounZiad A Massy

A1 Journal Article in KIDNEY INTERNATIONAL

Prognostic implications of plasma myoglobin levels in patients with chronic kidney disease

Aurélie LengletSophie LiabeufLucie DesjardinsNathalie NeirynckGriet GlorieuxHorst-Dieter LemkeRaymond VanholderMichel BrazierGabriel ChoukrounZiad A Massy

A1 Journal Article in INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

Renal hypoperfusion, rather than tubular damage is the main initial event in AKI during early sepsis

Jill VanmassenhoveWim Van BiesenGriet GlorieuxRaymond Vanholder

Urinary NGAL at admission does not provide additional information than serum creatinine, urine output and first 24h fluid balance, for prediction of AKI in septic patients at ICU

Jill VanmassenhoveWim Van BiesenGriet GlorieuxRaymond Vanholder

2011

Comparison of removal capacity of two consecutive generations of high-flux dialysers during different treatment modalities

Natalie MeertSunny ElootEva SchepersHorst-Dieter LemkeAnnemieke DhondtGriet GlorieuxMaria Van LandschootMARIA WATERLOOSRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

EGFR is a poor predictor of uremic toxin concentrations

Sunny ElootEva SchepersDV BarretoFC BarretoS LiabeurWim Van BiesenFrancis VerbekeGriet GlorieuxG ChoukrounZ Massy et al.

Estimated glomerular filtration rate is a poor predictor of concentration for a broad range of uremic toxins

Sunny ElootEva SchepersDaniela V BarretoFellype C BarretoSophie LiabeufWim Van BiesenFrancis VerbekeGriet GlorieuxGabriel ChoukrounZiad Massy et al.

A1 Journal Article in CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

New uremic toxins: which solutes should be removed?

Griet GlorieuxRaymond Vanholder

A1 Journal Article in HEMODIAFILTRATION : A NEW ERA

Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease

Eva SchepersDaniela V BarretoSophie LiabeufGriet GlorieuxSunny ElootFellype C BarretoZiad MassyRaymond Vanholder

A1 Journal Article in CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Toll-like receptor expression in monocytes in patients with chronic kidney disease and haemodialysis: relation with inflammation

Mehmet KocAhmet ToprakHakki ArikanZekaver OdabasiYesim ElbirAysin TulunayEbru AsiciogluEmel Eksioglu-DemiralpGriet GlorieuxRaymond Vanholder et al.

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Warning: the unfortunate end of p-cresol as a uraemic toxin

Raymond VanholderBert BammensHenriette de LoorGriet GlorieuxBjorn MeijersEva SchepersZiad MassyPieter Evenepoel

Editorial material

2010

Advantages of new hemodialysis membranes and equipment

Raymond VanholderGriet GlorieuxWim Van Biesen

A1 Journal Article in NEPHRON CLINICAL PRACTICE

Dinucleoside polyphosphates : newly detected uraemic compounds with an impact on leucocyte oxidative burst

Eva SchepersGriet GlorieuxVera JankowskiAnnemieke DhondtJoachim JankowskiRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Free p-cresylsulphate is a predictor of mortality in patients at different stages of chronic kidney disease

Sophie LiabeufDaniela V BarretoFellype C BarretoNatalie MeertGriet GlorieuxEva SchepersMohammed TemmarGabriel ChoukrounRaymond VanholderZiad A Massy

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Guanidino compounds as cause of cardiovascular damage in chronic kidney disease: an in vitro evaluation

Eva SchepersGriet GlorieuxLaetitia DouClaire CeriniNathalie GayrardLoïc LouvetCharlotte MaugardPierre PreusMaria Rodriguez-OrtizAngel Argiles et al.

A1 Journal Article in BLOOD PURIFICATION

Prospective evaluation of the change of predialysis protein-bound uremic solute concentration with postdilution online hemodiafiltration

Natalie MeertMARIA WATERLOOSMaria Van LandschootAnnemieke DhondtIngid LedeboGriet GlorieuxJan GoemanJohan Van der EyckenRaymond Vanholder

A1 Journal Article in ARTIFICIAL ORGANS

The gut: the forgotten organ in Uremia?

Eva SchepersGriet GlorieuxRaymond Vanholder

A1 Journal Article in BLOOD PURIFICATION

Griet GlorieuxEva SchepersRaymond Vanholder

Bookchapter in Cardiorenal syndrome : mechanisms, risk and treatment

2009

A novel bio-assay increases the detection yield of microbiological impurity of dialysis fluid, in comparison to the LAL-test

Griet GlorieuxEva SchepersRalf SchindlerHorst-Dieter LemkeFrancis VerbekeAnnemieke DhondtNorbert LameireRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Dinucleoside polyphosphates: newly detected uremic compounds with an impact on leukocyte oxidative burst

Eva SchepersGriet GlorieuxVera JankowskiAnnemieke DhondtJoachim JankowskiRaymond Vanholder

Effective removal of protein-bound uraemic solutes by different convective strategies: a prospective trial

Natalie MeertSunny ElootMARIA WATERLOOSMaria Van LandschootAnnemieke DhondtGriet GlorieuxIngrid LedeboRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

EFFECTIVE REMOVAL OF UREMIC SOLUTES BY DIFFERENT CONVECTIVE STRATEGIES: A PROSPECTIVE CROSS-OVER TRIAL.

Natalie MeertSunny ElootMarjan WaterloosMaria Van LandschootAnnemieke DhondtGriet GlorieuxRaymond Vanholder

Evolution of protein-bound uraemic solutes during predilution haemofiltration

Natalie MeertCharles BeerenhoutEva SchepersGriet GlorieuxJeroen KoomanRaymond Vanholder

A1 Journal Article in JOURNAL OF NEPHROLOGY

Flow cytometric calcium flux assay: evaluation of cytoplasmic calcium kinetics in whole blood leukocytes

Eva SchepersGriet GlorieuxAnnemieke DhondtLuc LeybaertRaymond Vanholder

A1 Journal Article in JOURNAL OF IMMUNOLOGICAL METHODS

Genetics/Genomics in Chronic Kidney Disease-Towards Personalized Medicine?

K LuttroppB LindholmJJ CarreroGriet GlorieuxEva SchepersRaymond VanholderM SchallingP StenvinkelL Nordfors

A1 Journal Article in SEMINARS IN DIALYSIS

Granulocyte-inhibitory proteins and other proteinaceous molecules in acute kidney injury

Griet GlorieuxEva SchepersWim Van BiesenNorbert LameireRaymond Vanholder

Bookchapter in Critical care nephrology

Guanidino Compounds as Uremic (Neuro)Toxins

Peter Paul De DeynRaymond VanholderSunny ElootGriet Glorieux

A1 Journal Article in SEMINARS IN DIALYSIS

Metabolic waste products in acute uremia

Griet GlorieuxEva SchepersWim Van BiesenNorbert LameireRaymond Vanholder

Bookchapter in Critical care nephrology

Platelet/Leukocyte Activation, Inflammation, and Uremia

Griet GlorieuxG CohenJ JankowskiRaymond Vanholder

A1 Journal Article in SEMINARS IN DIALYSIS

Role of symmetric dimethylarginine in vascular damage by increasing ROS via store-operated calcium influx in monocytes

Eva SchepersGriet GlorieuxAnnemieke DhondtLuc LeybaertRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients

FC BarretoDV BarretoS LiabeufNatalie MeertGriet GlorieuxM TemmarG ChoukrounRaymond VanholderZA Massy

A1 Journal Article in CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

SYMMETRIC DIMETHYLARGININE (SDMA):A PRO-INFLAMMATORY UREMIC TOXIN ENHANCING CELLULAR CALCIUM INFLUX AND ACTIVATING NF kappa B

Eva SchepersGriet GlorieuxLuc LeybaertAnnemieke DhondtRaymond Vanholder

The Role of EUTox in Uremic Toxin Research

Raymond VanholderO Abou-DeifA ArgilesU BaurmeisterJ BeigePeter BrouckaertPhilippe BrunetG CohenPP De DeynTB Drueke et al.

A1 Journal Article in SEMINARS IN DIALYSIS

Uremic Toxins in Acute Kidney Injury

S Herget-RosenthalGriet GlorieuxJ JankowskiV Jankowski

A1 Journal Article in SEMINARS IN DIALYSIS

2008

A bench to bedside view of uremic toxins

Raymond VanholderU BaurmeisterP BrunetG CohenGriet GlorieuxJ Jankowski

A1 Journal Article in JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

From uremic toxin retention to removal by convection: do we know enough?

Raymond VanholderNatalie MeertEva SchepersGriet Glorieux

A1 Journal Article in HEMODIALYSIS: FROM BASIC RESEARCH TO CLINICAL TRIALS

Impact of hemodialysis duration on the removal of uremic retention solutes

Sunny ElootWim Van BiesenAnnemieke DhondtH Van De WynkeleGriet GlorieuxPascal VerdonckRaymond Vanholder

A1 Journal Article in KIDNEY INTERNATIONAL

Review on uraemic toxins III: recommendations for handling uraemic retention solutes in vitro - towards a standardized approach for research on uraemia (vol 22, pg 3381, 2007)

G CohenGriet GlorieuxP ThornalleyEva SchepersNatalie MeertJ JankowskiVera JankowskiA ArgilesB AnderstamP Brunet et al.

The middle-molecule hypothesis 30 years after: lost and rediscovered in the universe of uremic toxicity?

Raymond VanholderSTEVEN VAN LAECKEGriet Glorieux

A1 Journal Article in JOURNAL OF NEPHROLOGY

Uraemic toxins and cardiovascular disease: in vitro research versus clinical outcome studies

Raymond VanholderSTEVEN VAN LAECKEFrancis VerbekeGriet GlorieuxWim Van Biesen

A2 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION PLUS

Uremic toxins: do we know enough to explain uremia?

Raymond VanholderNatalie MeertEva SchepersGriet Glorieux

A1 Journal Article in BLOOD PURIFICATION

Vitamin D binding protein and the need for vitamin D in hemodialysis patients

Marijn SpeeckaertGriet GlorieuxRaymond VanholderWim Van BiesenYouri TaesFrédéric ClementCharline WehlouJoris Delanghe

A1 Journal Article in JOURNAL OF RENAL NUTRITION

What is new in uremic toxicity?

Raymond VanholderSTEVEN VAN LAECKEGriet Glorieux

A1 Journal Article in PEDIATRIC NEPHROLOGY

2007

A novel highly efficient bio-assay to monitor microbiological purity of dialysis fluids

Griet GlorieuxEva SchepersR SchindlerFRANCIS VERBEKENorbert LameireRaymond Vanholder

Clearance of urea and difficult to remove uremic toxins when modifying dialysis time only

Sunny ElootWim Van BiesenAnnemieke DhondtGriet GlorieuxPascal VerdonckRaymond Vanholder

Impact of dialysis time on the removal of urea and difficult to remove uremic toxins

Sunny ElootWim Van BiesenAnnemieke DhondtRITA DE SMETGriet GlorieuxPascal VerdonckRaymond Vanholder

P-cresylsulphate, the main in vivo metabolite of p-cresol, activates leucocyte free radical production

Eva SchepersNatalie MeertGriet GlorieuxJan GoemanJohan Van der EyckenRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Pigmentation markers: more color in the picture of uremic toxicity?

Raymond VanholderGriet GlorieuxISABELLE DEVOLDERSTEVEN VAN LAECKE

Editorial material

Review on uraemic solutes II: variability in reported concentrations: causes and consequences

Raymond VanholderNatalie MeertEva SchepersGriet GlorieuxA ArgilesP BrunetG CohenT DrükeH MischakG Spasovski et al.

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Review on uraemic toxins III: recommendations for handling uraemic retention solutes in vitro - towards a standardized approach for research on uraemia

G CohenGriet GlorieuxP ThornalleyEva SchepersNatalie MeertJ JankowskiVera JankowskiA ArgilesB AnderstamP Brunet et al.

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

The impact of modifying only dialysis duration on the removal of uremic toxins

Sunny ElootWim Van BiesenAnnemieke DhondtGriet GlorieuxRaymond Vanholder

Uremic toxins in chronic renal failure

Griet GlorieuxEva SchepersRaymond Vanholder

A2 Journal Article in PRILOZI - MAKEDONSKA AKADEMIJA NA NAUKITE I UMETNOSTITE. ODDELENIE ZA BIOLOŠKI I MEDICINSKI NAUKI

2006

Clamping of the dialysate outlet line in the Genius (R) dialysis system does not alter dialysate flow or clearances

Wim Van BiesenSunny ElootA VerleysenGriet GlorieuxNic VeysRaymond VanholderNorbert Lameire

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Diadenosine polyphosphates: newly detected uremic compounds with an impact on leukocyte oxidative burst activity

Eva SchepersVera JankowskiGriet GlorieuxJ JankowskiRaymond Vanholder

Impact of iron sucrose therapy on leucocyte surface molecules and reactive oxygen species in haemodialysis patients

G GUZGriet GlorieuxRITA DE SMETMARIA WATERLOOSRaymond VanholderAnnemieke Dhondt

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

The guanidine SDMA which previously was considered inert, has a leukocyte stimulating effect

Eva SchepersGriet GlorieuxRaymond Vanholder

2005

Diadenosine polyphosphates: newly detected uremic compounds with an impact on the leukocyte oxidative burst activity

Eva SchepersVera JankowskiP JacobsGriet GlorieuxJ JankowskiNorbert LameireRaymond Vanholder

Dialysate partitioning in the Genius (R) batch hemodialysis system: Effect of temperature and solute concentration

Annemieke DhondtSunny ElootD De WachterRITA DE SMETMARIA WATERLOOSGriet GlorieuxNorbert LameirePascal VerdonckRaymond Vanholder

A1 Journal Article in KIDNEY INTERNATIONAL

Effect of specific guanidino compounds retained in uremia on the respiratory burst activity of leukocytes

Eva SchepersGriet GlorieuxP JacobsRITA DE SMETNorbert LameireRaymond Vanholder

Modification of leukocyte response by phenolic protein-bound uremic retention solutes

P JacobsGriet GlorieuxEva SchepersRITA DE SMETNorbert LameireRaymond Vanholder

New insights in uremic toxicity

Raymond VanholderGriet GlorieuxNorbert Lameire

A1 Journal Article in CARDIOVASCULAR DISORDERS IN HEMODIALYSIS

2004

In vitro evidence for immune activating effect of specific AGE structures retained in uremia.

Griet GlorieuxR HellingT HenleP BrunetR DeppischNorbert LameireRaymond Vanholder

A1 Journal Article in KIDNEY INTERNATIONAL

In vitro study of the potential role of guanidines in leukocyte functions related to atherogenesis and infection

Griet GlorieuxAnnemieke DhondtPeter JacobsJ Van LangeraertNorbert LameirePP De DeynRaymond Vanholder

A1 Journal Article in KIDNEY INTERNATIONAL

Interleukin/cytokine profiles in haemodialysis and in continuous peritoneal dialysis

Peter JacobsGriet GlorieuxRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

P-cresol, a uremic retention solute, alters the endothelial barrier function in vitro

C CeriniL DouF AnfossoF SabatierS MoalGriet GlorieuxRITA DE SMETRaymond VanholderF Dignat-GeorgeJ Sampol et al.

A1 Journal Article in THROMBOSIS AND HAEMOSTASIS

2003

Cumulative inhibitory effect of protein-bound uremic toxins on leukocyte response

Peter JacobsGriet GlorieuxRITA DE SMETNorbert LameireRaymond Vanholder

Effects of uremic ultrafiltrate on the regulation of the parathyroid cell cycle by calcitriol

A CANALEJOY ALMADENR DE SMETGriet GlorieuxB GARFIAF LUQUERaymond VanholderM RODRIGUEZ

A1 Journal Article in KIDNEY INTERNATIONAL

Immune stimulating effect of genuine uremic AGEs

Griet GlorieuxT HenleR HellingR DeppischNorbert LameireRaymond Vanholder

In vitro study of the potential role of guanidines in uremia-related atherogenesis and infection

Griet GlorieuxAnnemieke DhondtJ Van LangeraertNorbert LameirePP De DeynRaymond Vanholder

Low water-soluble uremic toxins

Raymond VanholderGriet GlorieuxRITA DE SMETPP De Deyn

A1 Journal Article in ADVANCES IN RENAL REPLACEMENT THERAPY

New insights in uremic toxins

Raymond VanholderGriet GlorieuxR DE SMETNorbert Lameire

A1 Journal Article in KIDNEY INTERNATIONAL

Review on uremic toxins : classification, concentration, and interindividual variability

Raymond VanholderRITA DE SMETGriet GlorieuxANGEL ARGILESULRICH BAURMEISTERPHILIPPE BRUNETWILLIAM CLARKGERALD COHENPETER PAUL DE DEYNREINHOLD DEPPISCH et al.

A1 Journal Article in KIDNEY INTERNATIONAL

Specific characteristics of peritoneal leucocyte populations during sterile peritonitis associated with icodextrin CAPD fluids

Griet GlorieuxNorbert LameireWim Van BiesenC DEQUIDTRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Studies on dialysate mixing in the Genius (R) single-pass batch system for hemodialysis therapy

Annemieke DhondtRaymond VanholderRV DE SMETSA CLAUSMA WATERLOOSGriet GlorieuxJR DELANGHENorbert Lameire

A1 Journal Article in KIDNEY INTERNATIONAL

Survival of hemodialysis patients and uremic toxin removal

Raymond VanholderRITA DE SMETGriet GlorieuxAnnemieke Dhondt

A1 Journal Article in ARTIFICIAL ORGANS

2002

The other side of the coin: impact of toxin generation and nutrition on the uremic syndrome

Raymond VanholderGriet GlorieuxNorbert Lameire

Editorial material

2001

Blunted response to vitamin D in uremia

Griet GlorieuxRaymond Vanholder

A1 Journal Article in KIDNEY INTERNATIONAL

Effect of uremic retention solutes and dialysis-related factors on immune dysfunction and resistance to calcitriol in chronic renal failure

Griet GlorieuxNorbert LameireRaymond Vanholder

The anti-proliferative effect of calcitriol on HL-60 cells is neutralized by uraemic biological fluids.

Griet GlorieuxC HsuR De SmetAnnemieke DhondtJoannes Van EmmeloMA WaterloosNorbert LameireJean PlumRaymond Vanholder

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

2000

Effect of regional citrate anticoagulation on leukopenia, complement activation, and expression of leukocyte surface molecules during hemodialysis with unmodified cellulose membranes.

Annemieke DhondtRaymond VanholderC TielemansGriet GlorieuxMA WaterloosR De SmetNorbert Lameire

A1 Journal Article in NEPHRON

Vitamin E-bonded cellulose membrane and hemodialysis bioincompatibility: Absence of an acute benefit on expression of leukocyte surface molecules.

Annemieke DhondtRaymond VanholderGriet GlorieuxMA WaterloosRené De SmetGerrit LesafferNorbert Lameire

A1 Journal Article in AMERICAN JOURNAL OF KIDNEY DISEASES

1998

Citrate anticoagulation does not correct cuprophane bioincompatibility as evaluated by the expression of leukocyte surface molecules.

Annemieke DhondtRaymond VanholderMA WaterloosGriet GlorieuxRené De SmetNorbert Lameire

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

In vitro effect of cefodizime, imipenem/cilastatin and co-trimoxazole on dexamethasone and cyclosporin a depressed phagocytosis.

Annemieke DhondtRaymond VanholderMA WaterloosGriet GlorieuxRené De SmetSeverin Ringoir

A1 Journal Article in INFECTION

Inhibition of calcitriol-induced monocyte CD14 expression by uremic toxins: Role of purines.

Griet GlorieuxCH HsuRené De SmetAnnemieke DhondtJ Van KaerP VogeleereNorbert LameireRaymond Vanholder

A1 Journal Article in JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

1997

p-cresol and uric acid: two old uremic toxins revisited

René De SmetGriet GlorieuxC HsuRaymond Vanholder

A1 Journal Article in KIDNEY INTERNATIONAL

1996

Biodegradation of poly(3-hydroxyalkanoates) in anaerobic sludge and characterization of a poly(3-hydroxyalkanoates) degrading anaerobic bacterium

Joris MergaertGriet GlorieuxLysiane HaubenVirginie StormsMargit MauJean Swings

A1 Journal Article in SYSTEMATIC AND APPLIED MICROBIOLOGY

Leukocyte CD14 and CD45 expression during hemodialysis: polysulfone versus cuprophane.

Annemieke DhondtRaymond VanholderMAF WaterloosGriet GlorieuxSeverin Ringoir

A1 Journal Article in NEPHRON

1995

Second symposium on uremic toxicity: summary of a symposium held in Gent, Belgium

Raymond VanholderA Van LooAnnemieke DhondtGriet GlorieuxRené De SmetS Ringoir