Research Explorer

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Researcher

Greet Verstichel

Awards & Distinctions

21 Results

2017

Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

Yasmine Van CaeneghemStijn De MunterPaola TieppoGlenn GoetgelukKarin WeeningGreet VerstichelSarah BonteTom TaghonGeorges LeclercqTessa Kerre et al.

A1 Journal Article in ONCOIMMUNOLOGY

The checkpoint for agonist selection precedes conventional selection in human thymus

Greet VerstichelDavid VermijlenLiesbet MartensGlenn GoetgelukMargreet BrouwerNicolas ThiaultYasmine Van CaeneghemStijn De MunterKarin WeeningSarah Bonte et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

Thymic development of a new innate CD8+ T cell population

Greet VerstichelBart VandekerckhoveTessa Kerre

2016

Early TCRA rearrangements favor development of agonist selected CD8ααhi T cells in human

Greet VerstichelGlenn GoetgelukLiesbet MartensYvan SaeysTessa KerreHilde CheroutreDavid VermijlenBart Vandekerckhove

The checkpoint for agonist selection precedes conventional selection in human thymus

Greet VerstichelDavid VermijlenLiesbet MartensGlenn GoetgelukYvan SaeysHilde CheroutreBart Vandekerckhove

2015

A candidate agonist selected CD8SP subpopulation in the human thymus and cord blood

Greet VerstichelAline Van AckerGeorges LeclercqBart Vandekerckhove

Chimeric antigen receptor transgenic, T cell receptor/CD3 negative monospecific T cells generated from cord blood CD34 positive cells

Yasmine Van CaeneghemGlenn GoetgelukKarin WeeningGreet VerstichelSarah BonteTom TaghonGeorges LeclercqFritz OffnerHinrich AbkenTessa Kerre et al.

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

Stijn VanheeKatrien De MulderYasmine Van CaeneghemGreet VerstichelNadine Van RoyBjörn MentenImke VelgheJan PhilippéDominique De BleserBart Lambrecht et al.

A1 Journal Article in HAEMATOLOGICA

2014

In vitro and in vivo functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system

Sarah BonteSylvia SnauwaertGlenn GoetgelukH StaussR StripeckeM HeemskerkYasmine Van CaeneghemGreet VerstichelStijn VanheeBart Vandekerckhove et al.

In vitro generation of mature, naive antigen-specific CD8⁺ T cells with a single T-cell receptor by agonist selection

Sylvia SnauwaertGreet VerstichelSarah BonteGlenn GoetgelukStijn VanheeYasmine Van CaeneghemKatrien De MulderCarlo HeirmanHans StaussMiriam HM Heemskerk et al.

A1 Journal Article in LEUKEMIA

2013

CMYB expression during human in vitro hematopoiesis

Stijn VanheeYasmine Van CaeneghemKatrien De MulderImke VelgheSylvie TaveirneNadine Van RoyBjörn MentenSylvia SnauwaertGreet VerstichelMelissa Dullaers et al.

In vitro generation of antigen-specific T-cells from CD34+haematopoietic progenitor cells: a new and promising immunotherapeutic strategy

Sylvia SnauwaertS Van CoppernolleGreet VerstichelGlenn GoetgelukYasmine Van CaeneghemStijn VanheeImke VelgheJean PlumTessa KerreBart Vandekerckhove

2012

Evaluation of the receptor for hyaluronic acid mediated motility as a tumour-specific antigen in AML

Sylvia SnauwaertStijn VanheeYasmine Van CaeneghemGreet VerstichelGlenn GoetgelukImke VelgheBart VandekerckhoveTessa Kerre

Notch induces T cell receptor gamma delta thymocytes to differentiate along a bipotent CD4 CD8 double positive pathway

Bart VandekerckhoveStefanie Van CoppernolleGreet VerstichelSylvia SnauwaertAnton LangerakTessa Kerre

Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway

Stefanie Van CoppernolleStijn VanheeGreet VerstichelSylvia SnauwaertA van der SpekImke VelgheMieke SinnesaelMH HeemskerkTom TaghonGeorges Leclercq et al.

A1 Journal Article in LEUKEMIA

RHAMM/HMMR (CD168) is not an ideal target antigen for immunotherapy of acute myeloid leukemia

Sylvia SnauwaertStijn VanheeGlenn GoetgelukGreet VerstichelYasmine Van CaeneghemImke VelgheJan PhilippéZwi N BernemanJean PlumTom Taghon et al.

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

TCR-dependency of in vitro T cell maturation in OP9-DL1 cocultures

Greet VerstichelSylvia SnauwaertTessa KerreBart Vandekerckhove

2011

Double positive and double negative TCR gamma delta plus cells independently generate mature functional TCR gamma delta plus cells in the human thymus

Stefanie Van CoppernolleStijn VanheeGreet VerstichelSylvia SnauwaertImke VelgheMieke SinnesaelA van der SpekTom TaghonGeorges LeclercqJean Plum et al.

2009

CD4 and CD8 TCR alpha beta cells are selected on MHC expressed on thymocyte precursors in OP9-DL1 cultures

Stefanie Van CoppernolleBart VandekerckhoveGreet VerstichelImke VelgheTom TaghonGeorges LeclercqJean PlumTessa Kerre

Functionally mature CD4 and CD8 TCRαβ cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells

Stefanie Van CoppernolleGreet VerstichelFrank TimmermansImke VelgheDavid VermijlenMagda De SmedtGeorges LeclercqJean PlumTom TaghonBart Vandekerckhove et al.

A1 Journal Article in JOURNAL OF IMMUNOLOGY

2008

OP9-DL1 Cell Line Supports the Development of Phenotypically and Functionally Mature Tcr alpha beta And Tcr gamma delta T Cells, through Both Conventional and Aberrant Developmental Pathways

Tessa KerreGreet VerstichelStefanie Van CoppernolleImke VelgheFrank TimmermansJean PlumBart Vandekerckhove