Research Explorer

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Researcher

Giel Tanghe

Awards & Distinctions

9 Results

2023

Functions of the RIP kinase family members in the skin

Corinne UrwylerGiel TangheMichael DevosPaco HulpiauYvan SaeysWim Declercq

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

2020

Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation

Michael DevosGiel TangheBarbara GilbertEvelien DierickMaud VerheirstraetenJosephine NemegeerRichard de ReuverSylvie LefebvreJolien De MunckJan Rehwinkel et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2018

Co-activation of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ in murine skin prevents worsening of atopic march

Julie DeckersNadia BougarneViacheslav MylkaSofie DesmetAstrid LuypaertMichael DevosGiel TangheJustine Van MoorleghemManon VanheerswynghelsLode De Cauwer et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Keratinocyte-Specific Ablation of RIPK4 Allows Epidermal Cornification but Impairs Skin Barrier Formation

Corinne UrwylerGiel TangheKirsten LeursBarbara GilbertRiet De RyckeMichiel De BruyneSaskia LippensSona BartunkovaPhilippe De GrooteCarien Niessen et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mechanistic insights into the regulation of RIPK4 and its function in skin homeostasis and pathology

Giel TangheWim Declercq

RIPK4 activity in keratinocytes is controlled by the SCFβ-TrCP ubiquitin ligase to maintain cortical actin organization

Giel TangheCorinne UrwylerPhilippe De GrooteEmmanuel DejardinPieter-Jan De BockKris GevaertPeter VandenabeeleWim Declercq

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

2016

Generation of a new Gateway-compatible inducible lentiviral vector platform allowing easy derivation of co-transduced cells

Philippe De GrooteSasker GrootjansSaskia LippensChantal EichpergerKirsten LeursIrene KahrGiel TangheInge BruggemanWouter De SchamphelaireCorinne Urwyler et al.

A1 Journal Article in BIOTECHNIQUES

2015

A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes

Philippe De GrooteHong Tran ThiMathias FransenGiel TangheCorinne UrwylerBram De CraeneKirsten LeursBarbara GilbertGriet Van ImschootRiet De Rycke et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Lineage tracing mediated by Cre-recombinase activity

Susanne VorhagenJoanna JackowSimona Georgina MohorGiel TangheLuna TanrikuluClaudia Skazik-VogtFrederik Tellkamp

A2 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY