Research Explorer

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Researcher

Gert-Jan Hofman

Awards & Distinctions

13 Results

2021

Fluorine NMR study of proline-rich sequences using fluoroprolines

Davy SinnaeveAbir Ben BouzayeneEmile OttoyGert-Jan HofmanEva ErdmannBruno LinclauIlya KuprovJosé MartinsVladimir TorbeevBruno Kieffer

A2 Journal Article in MAGNETIC RESONANCE

2019

Five-membered ring pucker conformational analysis of novel fluorinated prolines

Emile OttoySteven WorswickChris BrettGert-Jan HofmanBruno KiefferJosé MartinsBruno LinclauIlya KuprovDavy Sinnaeve

Synthesis and conformational properties of 3,4-difluoro-L-prolines

Gert-Jan HofmanEmile OttoyMark E. LightBruno KiefferJosé MartinsIlya KuprovDavy SinnaeveBruno Linclau

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

The synthesis of fluorinated proline analogues

Gert-Jan HofmanBruno LinclauDavy SinnaeveJosé Martins

2018

An accurate method for J-coupling based conformational analysis of five-membered rings : study of β- and γ-fluorinated prolines

Emile OttoySteven WorswickChris BrettGert-Jan HofmanBruno KiefferJosé MartinsBruno LinclauIlya KuprovDavy Sinnaeve

Full conformational characterization of novel fluorinated prolines

Emile OttoySteven WorswickChris BrettGert-Jan HofmanBruno KiefferJosé MartinsBruno LinclauIlya KuprovDavy Sinnaeve

Full conformational characterization of novel fluorinated prolines

Emile OttoySteven WorswickChris BrettGert-Jan HofmanBruno KiefferJosé MartinsBruno LinclauIlya KuprovDavy Sinnaeve

Minimising conformational bias in fluoroprolines through vicinal difluorination

Gert-Jan HofmanEmile OttoyMark E LightBruno KiefferIlya KuprovJosé MartinsDavy SinnaeveBruno Linclau

A1 Journal Article in CHEMICAL COMMUNICATIONS

Ring pucker and cis/trans isomerism of 3,4-difluoroprolines

Emile OttoyGert-Jan HofmanBruno LinclauJosé MartinsIlya KuprovDavy Sinnaeve

2017

Ab initio and NMR conformational analysis of β- and γ-fluorinated prolines

Emile OttoySteven WorswickChris BrettGert-Jan HofmanBruno KiefferJosé MartinsBruno LinclauIlya KuprovDavy Sinnaeve

Synthesis of fluoroprolines

Gert-Jan HofmanDavy SinnaeveJosé MartinsBruno Linclau

2016

Analysis of the five-membered ring pucker of β- and γ-fluorinated prolines by means of NMR spectroscopy and pseudorotation theory

Emile OttoyGert-Jan HofmanJosé MartinsBruno LinclauDavy Sinnaeve

Effects of fluorination on the conformation of proline : an NMR study

Emile OttoyGert-Jan HofmanBruno LinclauJosé MartinsDavy Sinnaeve