Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Researcher

George Dakwar

Awards & Distinctions

16 Results

2018

In vitro evaluation of anti-aggregation and degradation behavior of PEGylated polymeric nanogels under in vivo like conditions

Yinan ChenGeorge DakwarKevin BraeckmansTwan LammersWim E HenninkJosbert M Metselaar

A1 Journal Article in MACROMOLECULAR BIOSCIENCE

Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties

Bo LouAns De BeuckelaerGeorge DakwarKatrien RemautJohan GrootenKevin BraeckmansBruno De GeestEnrico MastrobattistaStefaan De KokerWim E. Hennink

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2017

Exploring the HYDRAtion method for loading siRNA on liposomes : the interplay between stability and biological activity in human undiluted ascites fluid

George DakwarKevin BraeckmansWim CeelenStefaan De SmedtKatrien Remaut

A1 Journal Article in DRUG DELIVERY AND TRANSLATIONAL RESEARCH

High-pressure nebulization as application route for the peritoneal administration of siRNA complexes

An-Katrien MinnaertGeorge DakwarJuan M BenitoJosé M García FernándezWim CeelenStefaan De SmedtKatrien Remaut

A1 Journal Article in MACROMOLECULAR BIOSCIENCE

Intracellular delivery of oligonucleotides in Helicobacter pylori by fusogenic liposomes in the presence of gastric mucus

Rita SantosGeorge DakwarElisa ZagatoToon BransCéu FigueiredoKoen RaemdonckNuno F AzevedoStefaan De SmedtKevin Braeckmans

A1 Journal Article in BIOMATERIALS

Nanomedicine-based intraperitoneal therapy for the treatment of peritoneal carcinomatosis : mission possible?

George DakwarMolood ShariatiWouter WillaertWim CeelenStefaan De SmedtKatrien Remaut

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

PEGylated and functionalized aliphatic polycarbonate polyplex nanoparticles for intravenous administration of HDAC5 siRNA in cancer therapy

Antoine FrèreAlexandra BaroniElodie HendrickAnne-Sophie DelvigneFrançois OrangeOlivier PeulenGeorge DakwarJérôme DiricqPhilippe DuboisBrigitte Evrard et al.

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

2016

Design of smart GE11-PLGA/PEG-PLGA blend nanoparticulate platforms for parenteral administration of hydrophilic macromolecular drugs : synthesis, preparation and in vitro/ex vivo characterization

Barbara ColzaniGiovanna SperanzaRossella DoratiBice ContiTiziana ModenaGiovanna BruniElisa ZagatoLotte VermeulenGeorge DakwarKevin Braeckmans et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Exploring the intraperitoneal route of administration for siRNA delivery in the treatment of pertitoneal carcinomatosis

George DakwarKatrien RemautStefaan De SmedtWim Ceelen

Freeze-dried mucoadhesive polymeric system containing pegylated lipoplexes : towards a vaginal sustained released system for siRNA

Tania FurstGeorge DakwarElisa ZagatoAnna LechanteurKatrien RemautBrigitte EvrardKevin BraeckmansGeraldine Piel

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2015

Disregarded effect of biological fluids in siRNA delivery : human ascites fluid severely restricts cellular uptake of nanoparticles

George DakwarKevin BraeckmansJo DemeesterWim CeelenStefaan De SmedtKatrien Remaut

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori

Rita SantosGeorge DakwarRanhua XiongKatrien ForierKatrien RemautStephan StremerschNuno GuimarãesSilvia FonteneteJesper WengelMarina Leite et al.

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

Intraperitoneal nonviral nucleic acid delivery in the treatment of peritoneal cancer

George DakwarStefaan De SmedtKatrien Remaut

Bookchapter in Intraperitoneal cancer therapy : principles and practice

Targeted decationized polyplexes for siRNA delivery

Luis NovoKaori M TakedaTamara PettetaGeorge DakwarJoep B van den DikkenbergKatrien RemautKevin BraeckmansCornelus F van NostrumEnrico MastrobattistaWim E Hennink

A1 Journal Article in MOLECULAR PHARMACEUTICS

2014

Colloidal stability of nano-sized particles in the peritoneal fluid : towards optimizing drug delivery systems for intraperitoneal therapy

George DakwarElisa ZagatoJoris DelangheSabina HobelAchim AignerHannelore DenysKevin BraeckmansWim CeelenStefaan De SmedtKatrien Remaut

A1 Journal Article in ACTA BIOMATERIALIA

Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy

Luís NovoLarissa Y RizzoSuzanne K GolombekGeorge DakwarBo LouKatrien RemautEnrico MastrobattistaCornelus F van NostrumWilhelm Jahnen-DechentFabian Kiessling et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE