Research Explorer

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Researcher

Geert Trooskens

Publications & Research Data

Awards & Distinctions

42 Results

2025

Comprehensive analysis of the melanoma DNA methylome identifies LY75 methylation as an independent marker predicting poor clinical outcome

Karin van den HurkKim LommenLouis CoussementDanique van den KerkhofMara BeckersGeert TrooskensLeander Van NesteMarloes OosterhofRemco van DoornJoost J. van den Oord et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

2019

Cost-effectiveness of a two-gene urine biomarker assay in MRI strategies for the initial detection of prostate cancer

Tim GoversMatthew J. ResnickGeert TrooskensWim Van CriekingeJack A. Schalken

Validation of a two-gene mRNA urine test for detection of high-grade prostate cancer in German men

Derya TilkiDaphne HesselsGeert TrooskensSusan MuldersMichael BrawerWim Van CriekingeJack GroskopfAlexander Haese

2018

Exploratory analysis of the human breast DNA methylation profile upon soymilk exposure

Louis CoussementSelin BolcaWim Van CriekingeGeert TrooskensKlaas MensaertKatrien PoelsNathalie RochePhillip BlondeelLode GodderisHerman Depypere et al.

A1 Journal Article in SCIENTIFIC REPORTS

2017

Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer

Linda JW BoschGeert TrooskensPetur SnaebjornssonVeerle MH CoupéSandra MongeraJosien C HaanSusan D RichmanMiriam KoopmanJolien TolTim De Meyer et al.

A1 Journal Article in ONCOTARGET

Epigenetic profiling in cancer

Geert TrooskensWim Van CriekingeTim De Meyer

Genome-wide DNA methylation profiling reveals methylation markers associated with 3q gain for detection of cervical precancer and cancer

Wina VerlaatPeter JF SnijdersPutri W NoviantiSaskia M WiltingLise MA De StrooperGeert TrooskensJohan VandersmissenWim Van CriekingeG Bea A WismanChris JLM Meijer et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

2016

Detection of high-grade prostate cancer using a urinary molecular biomarker-based risk score

Leander Van NesteRianne J HendriksSiebren DijkstraGeert TrooskensErik B CornelSander A JanninkHans de JongDaphne HesselsFrank P SmitWillem JG Melchers et al.

A1 Journal Article in EUROPEAN UROLOGY

Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer

Grant D StewartThomas PowlesChristophe Van NesteAlison MeynertFiach O'MahonyAlexander LairdDieter DeforceFilip Van NieuwerburghGeert TrooskensWim Van Criekinge et al.

A1 Journal Article in ONCOTARGET

Identification of high-grade prostate cancer using urine-based molecular biomarkers combined with clinical risk factors

Leander Van NesteGeert TrooskensRianne J HendriksJack SchalkenWim Van Criekinge

WRN promoter CpG island hypermethylation does not predict more favorable outcomes for patients with metastatic colorectal cancer treated with irinotecan-based therapy

Linda JW BoschYanxin LuoVictoria V LaoPetur SnaebjornssonGeert TrooskensIlse VlassenbroeckSandra MongeraWeiliang TangPiri WelcshJames G Herman et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

2015

Effect of sunitinib treatment on mutations and methylation in metastatic renal cancer

Grant StewartChristophe Van NesteAlison MeynertColin SempleFinch O'MahonyAlexander LairdAlan MackayGeert TrooskensWim Van CriekingeTim De Meyer et al.

Epigenetic effects of casein-derived opioid peptides in SH-SY5Y human neuroblastoma cells

Malav S. TrivediNathaniel W. HodgsonStephen J. WalkerGeert TrooskensVineeth NairRichard C. Deth

A1 Journal Article in NUTRITION & METABOLISM

Genome-wide DNA methylation detection by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison

Tim De MeyerPierre BadyGeert TrooskensSebastian KurscheidJocelyne BlochJohan M KrosJohannes A HainfellnerRoger StuppMauro DelorenziMonika E Hegi et al.

A1 Journal Article in SCIENTIFIC REPORTS

WRN Promoter CpG island hypermethylation does not predict a favourable outcome for irinotecan-treated metastatic colorectal cancer patients

LJW BoschY LuoVV LaoP SnaebjornssonGeert TrooskensI VlassenbroeckS MongeraW TangP WelcshJ Herman et al.

2014

Food-derived opioid peptides inhibit cysteine uptake with redox and epigenetic consequences

Malav S TrivediJayni S ShahSara Al-MughairyNathaniel W HodgsonBenjamin SimmsGeert TrooskensWim Van CriekingeRichard C Deth

A1 Journal Article in JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Next-generation technologies and data analytical approaches for epigenomics

Klaas MensaertSimon DenilGeert TrooskensWim Van CriekingeOlivier ThasTim De Meyer

A1 Journal Article in ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

SNP-guided identification of monoallelic DNA-methylation events from enrichment-based sequencing data

Sandra SteyaertWim Van CriekingeAyla De PaepeSimon DenilKlaas MensaertKatrien VandepitteWim Vanden BergheGeert TrooskensTim De Meyer

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Strategies for validation and testing of DNA methylation biomarkers

C NoehammerW PulvererMR HasslerM HofnerM WielscherK VierlingerT LiloglouD McCarthyTJ JensenA Nygren et al.

A1 Journal Article in EPIGENOMICS

ViVar: a comprehensive platform for the analysis and visualization of structural genomic variation

Tom SanteSarah VergultPieter-Jan VoldersWigard P KloostermanGeert TrooskensKatleen De PreterAnnelies DheedeneFranki SpelemanTim De MeyerBjörn Menten

A1 Journal Article in PLOS ONE

2013

An epigenomic next-generation sequencing approach to identify predictive markers for PARP inhibitor response in breast cancer cells

Tim De MeyerGeert TrooskensMascha K WibbeSebastian B BartmannManon van EngelandWim Van CriekingeVivianne C Tjan-HeijnenRuth KnüchelJürgen Veeck

Association of DNA promoter hypermethylation of decoy receptor 1 (DCR1) with poor response to irinotecan in metastatic colorectal cancer

Wim Van CriekingeLinda JW BoschGeert TrooskensPeter SnaebjornssonJosien HaanLorraine Cheryl PelosofMiriam KoopmanJolien TolJoost LouwagieLuc Dehaspe et al.

Combining in silico prediction and ribosome profiling in a genome-wide search for novel putatively coding sORFs

Jeroen CrappéWim Van CriekingeGeert TrooskensEisuke HayakawaWalter LuytenGeert BaggermanGerben Menschaert

A1 Journal Article in BMC GENOMICS

Comprehensive analysis of the basal cell carcinoma functional methylome

T BrinkhuizenS DenilGeert TrooskensWim Van CriekingeV WinnepenninckxK MosterdM van EngelandM van Steensel

Expression of type 2 orexin receptor in human endometrium and its epigenetic silencing in endometrial cancer

P DehanC CanonGeert TrooskensM RehliC MunautWim Van CriekingeP Delvenne

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Methylation-specific digital karyotyping of HPV16E6E7 expressing human keratinocytes identifies novel methylation events in cervical carcinogenesis

Renske DM SteenbergenMaté OngenaertSuzanne SnellenbergGeert TrooskensWendy F van der MeideDeeksha PandeyNoga Bloushtain-QimronKornelia PolyakChris JLM MeijerPeter JF Snijders et al.

A1 Journal Article in JOURNAL OF PATHOLOGY

Micropeptides, the next best thing after micro-RNA? Combining in silico prediction and ribosome profiling in a genome-wide search for novel micropeptides

Jeroen CrappéGeert TrooskensEisuke HayakawaWalter LuytenGeert BaggermanWim Van CriekingeGerben Menschaert

Quality evaluation of methyl binding domain based kits for enrichment DNA-methylation sequencing

Tim De MeyerEvi MampaeyMichaël VlemmixSimon DenilGeert TrooskensJean-Pierre RenardSarah De KeulenaerPierre DehanGerben MenschaertWim Van Criekinge

A1 Journal Article in PLOS ONE

Staphylococcal enterotoxin B influences the DNA methylation pattern in nasal polyp tissue : a preliminary study

Claudina Perez NovoYuan ZhangSimon DenilGeert TrooskensTim De MeyerWim Van CriekingePaul Van CauwenbergeLuo ZhangClaus Bachert

A1 Journal Article in ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY

Transcriptional analysis through RNA sequencing of giant cells induced by Meloidogyne graminicola in rice roots

Hongli JiGodelieve GheysenSimon DenilKeith LindseyJennifer F ToppingKamrun NaharAnnelies HaegemanWinnok De VosGeert TrooskensWim Van Criekinge et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

2012

GalNAc/Gal-binding Rhizoctonia solani agglutinin has antiproliferative activity in Drosophila melanogaster S2 cells via MAPK and JAK/STAT signaling

Mohamad HamshouEls Van DammeGianni VandenborreBart GhesquièreGeert TrooskensKris GevaertGuy Smagghe

A1 Journal Article in PLOS ONE

Genome‐wide RNA‐ and MBD‐sequencing in HCT116 and DKO cells as a global re‐expression model

Joachim De SchrijverGeert TrooskensLinda JW BoschPierre DehanBeatriz CarvalhoLeander Van NesteGerrit MeijerSteve BaylinWim Van Criekinge

Micropeptides, the next best thing after micro-RNA?: combining in silico prediction and ribosome profiling in a genome-wide search for novel micropeptides

Jeroen CrappéGeert TrooskensEisuke HayakawaWalter LuytenGeert BaggermanWim Van CriekingeGerben Menschaert

Transcriptional reprogramming by root knot and migratory nematode infection in rice

Tina KyndtSimon DenilAnnelies HaegemanGeert TrooskensLander BautersWim Van CriekingeTim De MeyerGodelieve Gheysen

A1 Journal Article in NEW PHYTOLOGIST

Transcriptome analysis of rice mature root tissue and root tips in early development by massive parallel sequencing

Tina KyndtSimon DenilAnnelies HaegemanGeert TrooskensTim De MeyerWim Van CriekingeGodelieve Gheysen

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

2011

A non-parametric method to assess the presence of significant DNA-methylation in enrichment-based NGS data

Klaas MensaertGeert TrooskensWim Van CriekingeOlivier ThasTim De Meyer

Charting the methylome

Geert TrooskensTim De MeyerSimon DenilWim Van Criekinge

Interaction of the tobacco lectin with histone proteins

Dieter SchouppeBart GhesquièreGerben MenschaertWinnok De VosStéphanie BourqueGeert TrooskensPaul ProostKris GevaertEls Van Damme

A1 Journal Article in PLANT PHYSIOLOGY

Micro peptides as a new class of bio-active peptides in Eukaryotes

Jeroen CrappéGerben MenschaertGeert TrooskensJoachim De SchrijverGeert BaggermanWim Van Criekinge

2010

Exploring 3D pooled next-generation sequencing using SNP-Cub^3

Joachim De SchrijverBram De WildeGeert TrooskensJo VandesompeleWim Van Criekinge

Next-generation high throughput interpretation and visualization of genetic variants

Joachim De SchrijverGeert Trooskens

2005

Phylogenetic trees: visualizing, customizing and detecting incongruence

Geert TrooskensDavid De BeuleFrederik DecouttereWim Van Criekinge

A1 Journal Article in BIOINFORMATICS