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Researcher
Geert Berx
Profile
Projects
Publications
Activities
Awards & Distinctions
173
Results
2024
Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics
Jana Ramon
Yanou Engelen
Herlinde De Keersmaecker
Ilia Goemaere
Deep Punj
Julián Mejía Morales
Cédric Bonte
Geert Berx
Esther Hoste
Stephan Stremersch
et al.
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2024
2023
A role for partial epithelial-to-mesenchymal transition in enabling stemness in homeostasis and cancer
Jeroen Verstappe
Geert Berx
A1
Journal Article
in
SEMINARS IN CANCER BIOLOGY
2023
Impact of EMT on regulated cell death and immune activation in colorectal cancer
Hanne Verschuere
Peter Vandenabeele
Geert Berx
Dissertation
2023
The epithelial-mesenchymal plasticity landscape: principles of design and mechanisms of regulation
Jef Haerinck
Steven Goossens
Geert Berx
A1
Journal Article
in
NATURE REVIEWS GENETICS
2023
2022
Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1
Yingying Han
Alvaro Villarreal-Ponce
Guadalupe Gutierrez
Quy Nguyen
Peng Sun
Ting Wu
Benjamin Sui
Geert Berx
Thomas Brabletz
Kai Kessenbrock
et al.
A1
Journal Article
in
CELL REPORTS
2022
Distinct transcriptional programs in ascitic and solid cancer cells induce different responses to chemotherapy in high-grade serous ovarian cancer
Nele Loret
Niels Vandamme
Jordy De Coninck
Joachim Taminau
Kato De Clercq
Gillian Blancke
Sven Jonckheere
Steven Goossens
Kelly Lemeire
Sofie De Prijck
et al.
A1
Journal Article
in
MOLECULAR CANCER RESEARCH
2022
Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis
Willeke de Haan
Wouter Dheedene
Katerina Apelt
Sofiane Decombas-Deschamps
Stefan Vinckier
Stefaan Verhulst
Andrea Conidi
Thomas Deffieux
Michael W. Staring
Petra Vandervoort
et al.
A1
Journal Article
in
CARDIOVASCULAR RESEARCH
2022
Epithelial-mesenchymal transition (EMT) as a therapeutic target
Sven Jonckheere
Jamie Adams
Dominic De Groote
Kyra Campbell
Geert Berx
Steven Goossens
A1
Journal Article
in
CELLS TISSUES ORGANS
2022
Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state
Farzaneh Ghazavi
Jelle Huysentruyt
Jordy De Coninck
Stephanie Kourula
Sofie Martens
Behrouz Hassannia
Tim Wartewig
Tatyana Divert
Ria Roelandt
Bastian Popper
et al.
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2022
MLKL deficiency in BrafV600EPten-/- melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice
Sofie Martens
Nozomi Takahashi
Gillian Blancke
Niels Vandamme
Hanne Verschuere
Tatyana Divert
Marnik Vuylsteke
Geert Berx
Peter Vandenabeele
A1
Journal Article
in
CELL DEATH & DISEASE
2022
Myb drives B-cell neoplasms and myeloid malignancies in vivo
Tim Pieters
André Pedro Pinto De Almeida
Sara T'Sas
Kelly Lemeire
Tino Hochepied
Geert Berx
Alex Kentsis
Steven Goossens
Pieter Van Vlierberghe
A1
Journal Article
in
BLOOD ADVANCES
2022
Therapeutic targeting of ZEB1-mediated EMT in metastatic colorectal cancer
Sven Jonckheere
Geert Berx
Steven Goossens
Dissertation
2022
2021
Cellular plasticity and heterogeneity in ovarian cancer progression and therapy resistance
Nele Loret
Geert Berx
Philippe Tummers
Bart Lambrecht
Dissertation
2021
Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice
Tim Pieters
Sara T'Sas
Stijn Vanhee
André Pedro Pinto De Almeida
Yasmine Driege
Juliette Roels
Wouter Van Loocke
Willem Daneels
Mathijs Baens
Arnaud Marchand
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2021
Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients
Marion Picard
Satoru Yonekura
Karolina Slowicka
Ioanna Petta
Conrad Rauber
Bertrand Routy
Corentin Richard
Valerio Iebba
Maryam Tidjani Alou
Sonia Becharef
et al.
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2021
Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity
Jueqiong Wang
Carlos Farkas
Aissa Benyoucef
Catherine Carmichael
Katharina Haigh
Nick Wong
Danny Huylebroeck
Marc P. Stemmler
Simone Brabletz
Thomas Brabletz
et al.
A1
Journal Article
in
PLOS BIOLOGY
2021
Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells
Maria Lasierra Losada
Melissa Pauler
Niels Vandamme
Steven Goossens
Geert Berx
Moritz Leppkes
Harald Schuhwerk
Simone Brabletz
Thomas Brabletz
Marc P. Stemmler
A1
Journal Article
in
CELL DEATH DISCOVERY
2021
Partial EMT takes the lead in cancer metastasis
Jef Haerinck
Geert Berx
Editorial material
2021
The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma
Manuel Ruh
Marc P. Stemmler
Isabell Frisch
Kathrin Fuchs
Ruthger Roey
Julia Kleemann
Maike Roas
Harald Schuhwerk
Rebecca L. Eccles
Abbas Agaimy
et al.
A1
Journal Article
in
JOURNAL OF PATHOLOGY
2021
The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer
Rahul Sreekumar
Hajir Al-Saihati
Muhammad Emaduddin
Karwan Moutasim
Massimiliano Mellone
Ashish Patel
Seval Kilic
Metin Cetin
Sule Erdemir
Marta Salgado Navio
et al.
A1
Journal Article
in
MOLECULAR ONCOLOGY
2021
XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells
Adam Wahida
Madeleine Mueller
Andreas Hiergeist
Bastian Popper
Katja Steiger
Caterina Branca
Markus Tschurtschenthaler
Thomas Engleitner
Sainitin Donakonda
Jordy De Coninck
et al.
A1
Journal Article
in
SCIENCE IMMUNOLOGY
2021
2020
Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma
Elien De Thaye
Koen Van de Vijver
Joni Van der Meulen
Joachim Taminau
Glenn Wagemans
Hannelore Denys
Jo Van Dorpe
Geert Berx
Wim Ceelen
Jan Van Bocxlaer
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2020
Guidelines and definitions for research on epithelial–mesenchymal transition
Jing Yang
Parker Antin
Geert Berx
Cédric Blanpain
Thomas Brabletz
Marianne Bronner
Kyra Campbell
Amparo Cano
Jordi Casanova
Gerhard Christofori
et al.
A1
Journal Article
in
NATURE REVIEWS MOLECULAR CELL BIOLOGY
2020
Immunodominant AH1 antigen-deficient necroptotic, but not apoptotic, murine cancer cells induce antitumor protection
Tania Love Aaes
Hanne Verschuere
Agnieszka Kaczmarek
Liesbeth Heyndrickx
Bartosz Wiernicki
Iris Delrue
Bram De Craene
Joachim Taminau
Tinneke Delvaeye
Mathieu Bertrand
et al.
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2020
Intrinsic balance between ZEB family members is important for melanocyte homeostasis and melanoma progression
Kenneth Bruneel
Jeroen Verstappe
Niels Vandamme
Geert Berx
A1
Journal Article
in
CANCERS
2020
Publisher correction : Zeb2 drives invasive and microbiota-dependent colon carcinoma
Karolina Slowicka
Ioanna Petta
Gillian Blancke
Esther Hoste
Emilie Dumas
Mozes Sze
Hanna-Kaisa Vikkula
Enrico Radaelli
Jody J. Haigh
Sven Jonckheere
et al.
Correction
2020
The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1
Catherine L. Carmichael
Jueqiong Wang
Thao Nguyen
Oluseyi Kolawole
Aissa Benyoucef
Charlotte De Mazière
Anna Milne
Sona Samuel
Kevin Robert Gillinder
Soroor Hediyeh-zadeh
et al.
A1
Journal Article
in
BLOOD
2020
The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype
Niels Vandamme
Geertrui Denecker
Kenneth Bruneel
Gillian Blancke
Ozden Akay
Joachim Taminau
Jordy De Coninck
Eva De Smedt
Nicolas Skrypek
Wouter Van Loocke
et al.
A1
Journal Article
in
CANCER RESEARCH
2020
Tumor engineered model for low-grade serous ovarian carcinoma (LGSOC) : mimicking the tumor environment on a cellular and biophysical level
Elly De Vlieghere
Eva Blondeel
Wim Ceelen
Bruno De Geest
Geert Berx
Sandra Van Vlierberghe
Olivier De Wever
C3
Conference
2020
Zeb2 drives invasive and microbiota-dependent colon carcinoma
Karolina Slowicka
Ioanna Petta
Gillian Blancke
Esther Hoste
Emilie Dumas
Mozes Sze
Hanna-Kaisa Vikkula
Enrico Radaelli
Jody J. Haigh
Sven Jonckheere
et al.
A1
Journal Article
in
NATURE CANCER
2020
2019
A new mouse model to study the role of ectopic Nanos3 expression in cancer
Vanessa Andries
Evi De Keuckelaere
Katrien Staes
Tino Hochepied
Joachim Taminau
Kelly Lemeire
Philippe Birembaut
Geert Berx
Frans Van Roy
A1
Journal Article
in
BMC CANCER
2019
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
Hannah Van Hove
Liesbet Martens
Isabelle Scheyltjens
Karen De Vlaminck
Ana Rita Pombo Antunes
Sofie De Prijck
Niels Vandamme
Sebastiaan De Schepper
Gert Van Isterdael
Charlotte Scott
et al.
A1
Journal Article
in
NATURE NEUROSCIENCE
2019
An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation
Daniel Haensel
Peng Sun
Adam L MacLean
Xianghui Ma
Yuan Zhou
Marc P Stemmler
Simone Brabletz
Geert Berx
Maksim V Plikus
Qing Nie
et al.
A1
Journal Article
in
EMBO REPORTS
2019
From neural crest cells to melanocytes : cellular plasticity during development and beyond
Niels Vandamme
Geert Berx
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2019
Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia
Gloria Milani
Filip Matthijssens
Wouter Van Loocke
Kaat Durinck
Juliette Roels
Sofie Peirs
Morgan Thénoz
Tim Pieters
Lindy Reunes
Béatrice Lintermans
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2019
Human decellularized dermal matrix seeded with adipose-derived stem cells enhances wound healing in a murine model : experimental study
Maarten Doornaert
Bernard Depypere
David Creytens
Heidi Declercq
Joachim Taminau
Kelly Lemeire
Stan Monstrey
Geert Berx
Phillip Blondeel
A2
Journal Article
in
ANNALS OF MEDICINE AND SURGERY
2019
Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies
Tim Pieters
Sara T'Sas
Lisa Demoen
André Pedro Pinto De Almeida
Lieven Haenebalcke
Filip Matthijssens
Kelly Lemeire
Jinke D'Hont
Frédérique Vanrockeghem
Tino Hochepied
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2019
The role of epithelial-to-mesenchymal plasticity in ovarian cancer progression and therapy resistance
Nele Loret
Hannelore Denys
Philippe Tummers
Geert Berx
A1
Journal Article
in
CANCERS
2019
Tumor engineering a clinical relevant model that recapitulates the tumor environment of peritoneal metastases in vitro and in vivo
Elly De Vlieghere
Emiel De Jaeghere
Glenn Wagemans
Thibaut Van Acker
Christian Vanhove
Sarah Neyts
Geert Berx
Frank Vanhaecke
Wim Ceelen
Bruno De Geest
et al.
C3
Conference
2019
USP7 cooperates with NOTCH1 to drive the oncogenic transcriptional program in T-cell leukemia
Qi Jin
Carlos A Martinez
Kelly M Arcipowski
Yixing Zhu
Blanca T Gutierrez-Diaz
Kenneth K Wang
Megan R Johnson
Andrew G Volk
Feng Wang
Jian Wu
et al.
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2019
Xenogen-free isolation and culture of human adipose mesenchymal stem cells
Maarten Doornaert
Elisabeth De Maere
Julien Colle
Heidi Declercq
Joachim Taminau
Kelly Lemeire
Geert Berx
Phillip Blondeel
A1
Journal Article
in
STEM CELL RESEARCH
2019
ZEB1 as 'jack-of-all-trades' in breast cancer progression
Eva De Smedt
Geert Berx
Dissertation
2019
ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms
Steven Goossens
Jueqiong Wang
Cedric Tremblay
Jelle De Medts
Sara T'Sas
Thao Nguyen
Jesslyn Saw
Katharina Haigh
David J Curtis
Pieter Van Vlierberghe
et al.
A1
Journal Article
in
HAEMATOLOGICA
2019
ZEB2 in T-cells and T-ALL
Stien De Coninck
Geert Berx
Tom Taghon
Pieter Van Vlierberghe
Steven Goossens
A2
Journal Article
in
ADVANCES IN BIOLOGICAL REGULATION
2019
2018
Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice
Marjolijn Renard
Suzanne Vanhauwaert
Marine Vanhomwegen
Ali Rihani
Niels Vandamme
Steven Goossens
Geert Berx
Pieter Van Vlierberghe
Jody J Haigh
Bieke Decaesteker
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2018
Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo
Emiel De Jaeghere
Elly De Vlieghere
Jasper Van Hoorick
Sandra Van Vlierberghe
Glenn Wagemans
Leen Pieters
Elodie Melsens
Marleen Praet
Jo Van Dorpe
Matthieu Boone
et al.
A1
Journal Article
in
BIOMATERIALS
2018
Nanos genes and their role in development and beyond
Evi De Keuckelaere
Paco Hulpiau
Yvan Saeys
Geert Berx
Frans Van Roy
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2018
TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia
Karen Verboom
Wouter Van Loocke
Jo Vandesompele
Niels Vandamme
Geert Berx
Liesbet Martens
Yvan Saeys
Pieter Van Vlierberghe
Franki Speleman
Kaat Durinck
C3
Conference
2018
The TLX1 oncogene modules the enhancer RNA landscape in T-ALL
Karen Verboom
Wouter Van Loocke
Jo Vandesompele
Niels Vandamme
Geert Berx
Yvan Saeys
Liesbet Martens
Pieter Van Vlierberghe
Franki Speleman
Kaat Durinck
C3
Conference
2018
The role of Nanos3 in tumor progression
Evi De Keuckelaere
Frans Van Roy
Geert Berx
Dissertation
2018
The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages
Charlotte Scott
Wouter T'Jonck
Liesbet Martens
Helena Todorov
Dorine Sichien
Bieke Soen
Johnny Bonnardel
Sofie De Prijck
Niels Vandamme
Robrecht Cannoodt
et al.
A1
Journal Article
in
IMMUNITY
2018
ZEB proteins in leukemia : friends, foes, or friendly foes?
Bieke Soen
Niels Vandamme
Geert Berx
Jürg Schwaller
Pieter Van Vlierberghe
Steven Goossens
A2
Journal Article
in
HEMASPHERE
2018
ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition
Nicolas Skrypek
Kenneth Bruneel
Cindy Vandewalle
Eva De Smedt
Bieke Soen
Nele Loret
Joachim Taminau
Steven Goossens
Niels Vandamme
Geert Berx
A1
Journal Article
in
EPIGENETICS & CHROMATIN
2018
Zeb1 and Zeb2 : master regulators of mononuclear phagocyte development and homeostasis
Bieke Soen
Geert Berx
Charlotte Scott
Dissertation
2018
2017
Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research
Glenn Vergauwen
Bert Dhondt
Jan Van Deun
Eva De Smedt
Geert Berx
Evy Timmerman
Kris Gevaert
Ilkka Miinalainen
Veronique Cocquyt
Geert Braems
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2017
EMT transcription factors in cancer development re-evaluated : beyond EMT and MET
Steven Goossens
Niels Vandamme
Pieter Van Vlierberghe
Geert Berx
A1
Journal Article
in
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
2017
EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research
Jan Van Deun
Pieter Mestdagh
Patrizia Agostinis
Özden Akay
Sushma Anand
Jasper Anckaert
Zoraida Andreu Martinez
Tine Baetens
Els Beghein
Laurence Bertier
et al.
A1
Journal Article
in
NATURE METHODS
2017
Elevated ΔNp63α levels facilitate epidermal and biliary oncogenic transformation
Michael Devos
Barbara Gilbert
Geertrui Denecker
Kirsten Leurs
Conor Mc Guire
Kelly Lemeire
Tino Hochepied
Marnik Vuylsteke
Jo Lambert
Caroline Van den Broecke
et al.
A1
Journal Article
in
JOURNAL OF INVESTIGATIVE DERMATOLOGY
2017
Epithelial-to-mesenchymal transition : epigenetic reprogramming driving cellular plasticity
Nicolas Skrypek
Steven Goossens
Eva De Smedt
Niels Vandamme
Geert Berx
A1
Journal Article
in
TRENDS IN GENETICS
2017
Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo
Emiel De Jaeghere
Elly De Vlieghere
Jasper Van Hoorick
Glenn Wagemans
Leen Pieters
Elodie Melsens
Sara Neyt
Rouba Ghobeira
Rino Morent
Jo Van Dorpe
et al.
C3
Conference
2017
In vivo visualisation of vessel formation in peritoneal tumour scaffolds with μCT
Emiel De Jaeghere
Elly De Vlieghere
Sara Neyt
Bert Vandeghinste
Jasper Van Hoorick
Glenn Wagemans
Leen Pieters
Elodie Melsens
Geert Berx
Sandra Van Vlierberghe
et al.
C3
Conference
2017
Mouse cutaneous melanoma induced by mutant BRaf arises from expansion and dedifferentiation of mature pigmented melanocytes
Corinna Kohler
David Nittner
Florian Rambow
Enrico Radaelli
Fabio Stanchi
Niels Vandamme
Arianna Baggiolini
Lukas Sommer
Geert Berx
Joost J van den Oord
et al.
A1
Journal Article
in
CELL STEM CELL
2017
Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia
Steven Goossens
Sofie Peirs
Wouter Van Loocke
Jueqiong Wang
Mina Takawy
Filip Matthijssens
Stefan E Sonderegger
Katharina Haigh
Thao Nguyen
Niels Vandamme
et al.
A1
Journal Article
in
BLOOD
2017
Structure-function studies in mouse embryonic stem cells using recombinase-mediated cassette exchange
Tim Pieters
Lieven Haenebalcke
Kenneth Bruneel
Niels Vandamme
Tino Hochepied
Jolanda van Hengel
Dagmar Wirth
Geert Berx
Jody J Haigh
Frans Van Roy
et al.
A1
Journal Article
in
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
2017
Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia
Sofie Peirs
V Frismantas
Filip Matthijssens
W Van Loocke
Tim Pieters
Niels Vandamme
Béatrice Lintermans
MP Dobay
Geert Berx
Bruce Poppe
et al.
A1
Journal Article
in
LEUKEMIA
2017
ZEB1 and ZEB2 dictate melanocyte differentiation and melanoma phenotype switching
Niels Vandamme
Geert Berx
Dissertation
2017
Zeb2 regulates cell fate at the exit from epiblast state in mouse embryonic stem cells
Agata Stryjewska
Ruben Dries
Tim Pieters
Griet Verstappen
Andrea Conidi
Kathleen Coddens
Annick Francis
Lieve Umans
Wilfred FJ van IJcken
Geert Berx
et al.
A1
Journal Article
in
STEM CELLS
2017
2016
BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Tim Pieters
Niels Vandamme
Geert Berx
Bruce Poppe
Pieter Van Vlierberghe
C3
Conference
2016
BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Tim Pieters
Niels Vandamme
Geert Berx
Bruce Poppe
Pieter Van Vlierberghe
C3
Conference
2016
Cyclin D2 overexpression recapitulates mantle cell lymphoma in mice
Tim Pieters
Steven Goossens
Sara T'Sas
Geert Berx
Jody J Haigh
Pieter Van Vlierberghe
C3
Conference
2016
Fast generation of conditional ROSA26-based mouse models that recapitulate genomic events in human T-ALL
Tim Pieters
Steven Goossens
Sara T'Sas
Lieven Haenebalcke
Tino Hochepied
Béatrice Lintermans
Sofie Peirs
Filip Matthijssens
J Haigh
Geert Berx
et al.
C3
Conference
2016
Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia
Gloria Milani
Kaat Durinck
Filip Matthijssens
Sofie Peirs
Tim Pieters
Lindy Reunes
Béatrice Lintermans
Niels Vandamme
Tim Lammens
Yunlei Li
et al.
C3
Conference
2016
LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19
Hetty Helsmoortel
Barbara De Moerloose
Tim Pieters
Farzaneh Ghazavi
Silvia Bresolin
Helene Cave
Andrica de Vries
Valerie de Haas
Christian Flotho
Veerle Labarque
et al.
A1
Journal Article
in
HAEMATOLOGICA
2016
Oncogenic ZEB2 activation drives sensitivity towards LSD1 inhibition in T-Cell acute lymphoblastic leukemia
Steven Goossens
Sofie Peirs
Geert Berx
Pieter Van Vlierberghe
Jody J Haigh
C3
Conference
2016
Targeting BET family proteins improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Béatrice Lintermans
Tim Pieters
Niels Vandamme
Geert Berx
Bruce Poppe
Pieter Van Vlierberghe
C3
Conference
2016
Targeting BET family proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia
Sofie Peirs
Viktoras Frismantas
Filip Matthijssens
Béatrice Lintermans
Tim Pieters
Niels Vandamme
Wouter Van Loocke
Geert Berx
Bruce Poppe
Jean-Pierre Bourquin
et al.
C3
Conference
2016
The combination of ABT-199 and JQ1 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Tim Pieters
Niels Vandamme
Béatrice Lintermans
Lindy Reunes
Geert Berx
Bruce Poppe
Pieter Van Vlierberghe
C3
Conference
2016
The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2
Charlotte Scott
Bieke Soen
Liesbet Martens
Nicolas Skrypek
Wouter Saelens
Joachim Taminau
Gillian Blancke
Gert Van Isterdael
Danny Huylebroeck
Jody Haigh
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2016
Tissue factor induced by epithelial-mesenchymal transition triggers a procoagulant state that drives metastasis of circulating tumor cells
Morgane Bourcy
Meggy Suarez-Carmona
Justine Lambert
Marie-Emilie Francart
Hélène Schroeder
Céline Delierneux
Nicolas Skrypek
Erik W Thompson
Guy Jérusalem
Geert Berx
et al.
A1
Journal Article
in
CANCER RESEARCH
2016
Vaccination with necroptotic cancer cells induces efficient anti-tumor immunity
Tania Love Aaes
Agnieszka Kaczmarek
Tinneke Delvaeye
Bram De Craene
Stefaan De Koker
Liesbeth Heyndrickx
Iris Delrue
Joachim Taminau
Bartosz Wiernicki
Philippe De Groote
et al.
A1
Journal Article
in
CELL REPORTS
2016
p120 Catenin-mediated stabilization of E-cadherin is essential for primitive endoderm specification
Tim Pieters
Steven Goossens
Lieven Haenebalcke
Vanessa Andries
Agata Stryjewska
Riet De Rycke
Kelly Lemeire
Tino Hochepied
Danny Huylebroeck
Geert Berx
et al.
A1
Journal Article
in
PLOS GENETICS
2016
2015
A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes
Philippe De Groote
Hong Tran Thi
Mathias Fransen
Giel Tanghe
Corinne Urwyler
Bram De Craene
Kirsten Leurs
Barbara Gilbert
Griet Van Imschoot
Riet De Rycke
et al.
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2015
Development and characterization of a new human hepatic cell line
Eva Ramboer
Bram De Craene
Joey De Kock
Geert Berx
Vera Rogiers
Tamara Vanhaecke
Mathieu Vinken
A1
Journal Article
in
EXCLI JOURNAL
2015
NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest
Vanessa Andries
Karl Vandepoele
Katrien Staes
Geert Berx
Pieter Bogaert
Gert Van Isterdael
Daisy Ginneberge
Eef Parthoens
Jonathan Vandenbussche
Kris Gevaert
et al.
A1
Journal Article
in
BMC CANCER
2015
Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium
Katja Horvay
Thierry Jardé
Franca Casagranda
Victoria M Perreau
Katharina Haigh
Christian M Nefzger
Reyhan Akhtar
Thomas Gridley
Geert Berx
Jody Haigh
et al.
A1
Journal Article
in
EMBO JOURNAL
2015
Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection
Mary van Helden
Steven Goossens
Cécile Daussy
Anne-Laure Mathieu
Fabrice Faure
Antoine Marçais
Niels Vandamme
Natalie Farla
Katia Mayol
Sébastien Viel
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2015
Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells
Elly De Vlieghere
Félix Gremonprez
Laurine Verset
Lore Mariën
Christopher Jones
Bram De Craene
Geert Berx
Benedicte Descamps
Christian Vanhove
Jean Paul Remon
et al.
A1
Journal Article
in
BIOMATERIALS
2015
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling
Steven Goossens
Enrico Radaelli
Odile Blanchet
Kaat Durinck
Joni Van der Meulen
Sofie Peirs
Tom Taghon
Cedric S Tremblay
Magdaline Costa
Morvarid Farhang Ghahremani
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2015
2014
Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability
Mauricio Quimbaya Gomez
Eric Raspé
Geertrui Denecker
Bram De Craene
Ria Roelandt
Wim Declercq
Xavier Sagaert
Lieven De Veylder
Geert Berx
A1
Journal Article
in
NEOPLASIA
2014
Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential
Bram De Craene
Geertrui Denecker
Petra Vermassen
Joachim Taminau
C Mauch
Annie Derore
J Jonkers
E Fuchs
Geert Berx
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2014
Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression
Geertrui Denecker
Niels Vandamme
Ozden Akay
D Koludrovic
Joachim Taminau
Kelly Lemeire
Alexander Gheldof
Bram De Craene
Mireille Van Gele
Lieve Brochez
et al.
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2014
Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity
Niels Vandamme
Geert Berx
A2
Journal Article
in
FRONTIERS IN ONCOLOGY
2014
Strategies for immortalization of primary hepatocytes
Eva Ramboer
Bram De Craene
Joery De Kock
Tamara Vanhaecke
Geert Berx
Vera Rogiers
Mathieu Vinken
A1
Journal Article
in
JOURNAL OF HEPATOLOGY
2014
ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins
Marianthi Tatari
Bram De Craene
Bieke Soen
Joachim Taminau
Petra Vermassen
Steven Goossens
Katharina Haigh
Silvia Cazzola
Jo Lambert
Danny Huylebroeck
et al.
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2014
2013
Cadherins and epithelial-to-mesenchymal transition
Alexander Gheldof
Geert Berx
A1
Journal Article
in
Progress in Molecular Biology and Translational Science
2013
Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1
Veronique van den Berghe
Elke Stappers
Bram Vandesande
Jordane Dimidschstein
Roel Kroes
Annick Francis
Andrea Conidi
Flore Lesage
Ruben Dries
Silvia Cazzola
et al.
A1
Journal Article
in
NEURON
2013
Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression
Benjamin Koopmansch
Geert Berx
Jean-Michel Foidart
Christine Gilles
Rosita Winkler
A1
Journal Article
in
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
2013
Regulatory networks defining EMT during cancer initiation and progression
Bram De Craene
Geert Berx
A1
Journal Article
in
NATURE REVIEWS CANCER
2013
2012
Concepts of metastasis in flux: the stromal progression model
Jonathan P Sleeman
Gerhard Christofori
Riccardo Fodde
John G Collard
Geert Berx
Charles Decraene
Curzio Rüegg
A1
Journal Article
in
SEMINARS IN CANCER BIOLOGY
2012
Evolutionary functional analysis and molecular regulation of the ZEB transcription factors
Alexander Gheldof
Paco Hulpiau
Frans Van Roy
Bram De Craene
Geert Berx
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2012
Gene expression profiling to dissect the complexity of cancer biology: pitfalls and promise
Eric Raspé
Charles Decraene
Geert Berx
A1
Journal Article
in
SEMINARS IN CANCER BIOLOGY
2012
Identification of putative cancer genes through data integration and comparative genomics between plants and humans
Mauricio Quimbaya Gomez
Klaas Vandepoele
Eric Raspé
Michiel Matthijs
Stijn Dhondt
Gerrit Beemster
Geert Berx
Lieven De Veylder
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2012
2011
Functional analysis of the EMT inducing transcription factor ZEB1 during malignant carcinoma progression
Alexander Gheldof
Geert Berx
Dissertation
2011
Identification of novel conserved cell cycle genes through data integration and comparative genomics between plants and humans
Mauricio Quimbaya Gomez
Lieven De Veylder
Geert Berx
Dissertation
2011
The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization
Steven Goossens
Viktor Janzen
Sona Bartunkova
Tomomasa Yokomizo
Benjamin Drogat
Mihaela Crisan
Katharina Haigh
Eve Seuntjens
Lieve Umans
Tamara Riedt
et al.
A1
Journal Article
in
BLOOD
2011
2010
Key signalling nodes in mammary gland development and cancer: the snail1-twist1 conspiracy in malignant breast cancer progression
Ellen Foubert
Bram De Craene
Geert Berx
A1
Journal Article
in
BREAST CANCER RESEARCH
2010
Module network inference from a cancer gene expression data set identifies microRNA regulated modules
Eric Bonnet
Marianthi Tatari
Anagha Joshi
Tom Michoel
Kathleen Marchal
Geert Berx
Yves Van de Peer
A1
Journal Article
in
PLOS ONE
2010
Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma
Michael Herfs
Pascale Hubert
Meggy Suarez-Carmona
Anca Reschner
Sven Saussez
Geert Berx
Pierre Savagner
Jacques Boniver
Philippe Delvenne
A1
Journal Article
in
AMERICAN JOURNAL OF PATHOLOGY
2010
The MCM-Binding Protein ETG1 Aids Sister Chromatid Cohesion Required for Postreplicative Homologous Recombination Repair
Naoki Takahashi
Mauricio Quimbaya Gomez
Veit Schubert
Tim Lammens
Klaas Vandepoele
Ingo Schubert
Minami Matsui
Dirk Inzé
Geert Berx
Lieven De Veylder
A1
Journal Article
in
PLOS GENETICS
2010
2009
Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes
J Van den Bossche
Pieter Bogaert
Jolanda van Hengel
Chris Guerin
Geert Berx
K Movahedi
R Van den Bergh
A Pereira-Fernandes
JMC Geuns
H Pircher
et al.
A1
Journal Article
in
BLOOD
2009
Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells
Omar Nyabi
Michaël Naessens
Katharina Haigh
Agnieszka Gembarska
Steven Goossens
Marion Maetens
Sarah De Clercq
Benjamin Drogat
Lieven Haenebalcke
Sona Bartunkova
et al.
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2009
Involvement of members of the Cadherin superfamily in cancer
Geert Berx
Frans Van Roy
A1
Journal Article
in
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
2009
The role of the ZEB family of transcription factors in development and disease
Cindy Vandewalle
Frans Van Roy
Geert Berx
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2009
Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex affair
Jean-Christophe Marine
Geert Berx
A1
Journal Article
in
BREAST CANCER RESEARCH
2009
2008
A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes
Karl Vandepoele
Vanessa Andries
Nadine Van Roy
Katrien Staes
Jo Vandesompele
Genevieve Laureys
Els De Smet
Geert Berx
Franki Speleman
Frans Van Roy
A1
Journal Article
in
PLOS ONE
2008
A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the the human NBPF1 and ACCN1 genes
Frans Van Roy
Klaas Vandepoele
Nadine Van Roy
Vanessa Andries
Katrien Staes
Jo Vandesompele
Genevieve Laureys
Els De Smet
Geert Berx
Franki Speleman
C3
Conference
2008
Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front
Olivier De Wever
Patrick Pauwels
Bram De Craene
M SABBAH
S EMAMI
G REDEUILH
C GESPACH
Marc Bracke
Geert Berx
A1
Journal Article
in
HISTOCHEMISTRY AND CELL BIOLOGY
2008
Snail promotes Wnt target gene expression and interacts with beta-catenin
V STEMMER
Bram De Craene
Geert Berx
J BEHRENS
A1
Journal Article
in
ONCOGENE
2008
The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression
A BONNOMET
M POLETTE
Kristin Strumane
C GILLES
V DALSTEIN
C KILEZTKY
Geert Berx
Frans Van Roy
P BIREMBAUT
B NAWROCKI-RABY
A1
Journal Article
in
ONCOGENE
2008
The cell-cell adhesion molecule E-cadherin
Frans Van Roy
Geert Berx
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2008
Transforming growth factor-beta 1-mediated slug and snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression
M HERFS
P HUBERT
N KHOLOD
JH CABERG
C GILLES
Geert Berx
P SAVAGNER
J BONIVER
P DELVENNE
A1
Journal Article
in
AMERICAN JOURNAL OF PATHOLOGY
2008
2007
Direct repression of cyclin d1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition
J MEJLVANG
M KRIAJEVSKA
Cindy Vandewalle
T CHERNOVA
AE SAYAN
Geert Berx
JK MELLON
E TULCHINSKY
A1
Journal Article
in
MOLECULAR BIOLOGY OF THE CELL
2007
Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer
Geert Berx
Eric Raspé
G CHRISTOFORI
JP THIERY
JP SLEEMAN
A1
Journal Article
in
CLINICAL & EXPERIMENTAL METASTASIS
2007
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail
AJ EVANS
RC RUSSELL
O ROCHE
TN BURRY
JE FISH
VWK CHOW
WY KIM
A SARAVANAN
MA MAYNARD
ML GERVAIS
et al.
A1
Journal Article
in
MOLECULAR AND CELLULAR BIOLOGY
2007
2006
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer
S SPADERNA
O SCHMALHOFER
F HLUBEK
Geert Berx
A EGER
S MERKEL
A JUNG
T KIRCHNER
T BRABLETZ
A1
Journal Article
in
GASTROENTEROLOGY
2006
E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion
Kristin Strumane
Arnaud Bonnomet
Christophe Stove
Roosmarijn Vandenbroucke
Beatrice Nawrocki-Raby
Erik Bruyneel
Marcus Mareel
Philippe Birembaut
Geert Berx
Frans Van Roy
A1
Journal Article
in
CANCER RESEARCH
2006
Modulation of iron transport proteins in human colorectal carcinogenesis
MJ BROOKES
S HUGHES
FE TURNER
G REYNOLDS
N SHARMA
T ISMAIL
Geert Berx
AT MCKIE
N HOTCHIN
GJ ANDERSON
et al.
A1
Journal Article
in
GUT
2006
Regulation of vimentin by SIP1 in human epithelial breast tumor cells
S BINDELS
M MESTDAGT
Cindy Vandewalle
N JACOBS
L VOLDERS
A NOEL
Frans Van Roy
Geert Berx
JM FOIDART
C GILLES
A1
Journal Article
in
ONCOGENE
2006
Snail in the frame of malignant tumor recurrence
Bram De Craene
Geert Berx
A1
Journal Article
in
BREAST CANCER RESEARCH
2006
2005
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
A EGER
K AIGNER
S SONDEREGGER
B DAMPIER
S OEHLER
M SCHREIBER
Geert Berx
A CANO
H BEUG
R FOISNER
A1
Journal Article
in
ONCOGENE
2005
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions
Cindy Vandewalle
Joke Comijn
Bram De Craene
Petra Vermassen
Erik Bruyneel
H Andersen
E Tulchinsky
Frans Van Roy
Geert Berx
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2005
The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program
Bram De Craene
Barbara Gilbert
Christophe Stove
Erik Bruyneel
Frans Van Roy
Geert Berx
A1
Journal Article
in
CANCER RESEARCH
2005
Unraveling signalling cascades for the Snail family of transcription factors
Bram De Craene
Frans Van Roy
Geert Berx
A1
Journal Article
in
CELLULAR SIGNALLING
2005
2004
Cadherins in cancer
Kristin Strumane
Geert Berx
Frans Van Roy
Bookchapter
in
Handbook of Experimental Pharmacology
2004
Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons
Katleen De Preter
Filip Pattyn
Geert Berx
Kristin Strumane
Björn Menten
Frans Van Roy
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
BMC GENOMICS
2004
Epithelial cell plasticity by dynamic transcriptional regulation of E-cadherin
Geert Berx
Frans Van Roy
Bookchapter
in
Rise and fall of epithelial phenotype
2004
GATA-4 and MEF2C transcription factors control the tissue-specific expression of the αT-catenin gene CTNNA3
Griet Vanpoucke
Steven Goossens
Bram De Craene
Barbara Gilbert
Frans Van Roy
Geert Berx
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2004
2003
Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells
PHILIP DEBRUYNE
Stefan Vermeulen
Geert Berx
M POCARD
ASC DA ROCHA
XD LI
L CIRNES
MF POUPON
Frans Van Roy
Marcus Mareel
A1
Journal Article
in
ONCOGENE
2003
Identification of excretory-secretory products of larval and adult Ostertagia ostertagi by immunoscreening of cDNA libraries
Isabel Vercauteren
Peter Geldhof
Iris Peelaers
Edwin Claerebout
Geert Berx
Jozef Vercruysse
A1
Journal Article
in
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
2003
Identification of potential protective antigens of Ostertagia ostertagi with local antibody probes
Veerle De Maere
Isabel Vercauteren
Heidi Saverwyns
Edwin Claerebout
Geert Berx
Jozef Vercruysse
C1
Conference
2003
Protein disulphide isomerase of Ostertagia ostertagi: an excretory-secretory product of L4 and adult worms?
Peter Geldhof
Isabel Vercauteren
D KNOX
V DEMAERE
Annelies Van Zeveren
Geert Berx
Jozef Vercruysse
Edwin Claerebout
A1
Journal Article
in
INTERNATIONAL JOURNAL FOR PARASITOLOGY
2003
The role of E-cadherin in epithelial differentiation and cancer progression
Kristin Strumane
Frans Van Roy
Geert Berx
Bookchapter
in
Recent Research Development in Cellular Biochemistry
2003
2002
Identification of potential protective antigens of Ostertagia ostertagi with local antibody probes
Veerle De Maere
Isabel Vercauteren
Heidi Saverwyns
Edwin Claerebout
Geert Berx
Jozef Vercruysse
A1
Journal Article
in
PARASITOLOGY
2002
Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type I patients.
Nadine Van Roy
Jo Vandesompele
Geert Berx
K STAES
Mireille Van Gele
Els De Smet
Anne De Paepe
Genevieve Laureys
P VAN DER DRIFT
R VERSTEEG
et al.
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2002
Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells.
N MULLER
A REINACHER-SCHICK
S BALDUS
Jolanda van Hengel
Geert Berx
A BAAR
Frans Van Roy
W SCHMIEGEL
I SCHWARTE-WALDHOFF
A1
Journal Article
in
ONCOGENE
2002
2001
E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma.
JC MACHADO
C OLIVEIRA
R CARVALHO
P SOARES
Geert Berx
C CALDAS
R SERUCA
F CARNEIRO
M SOBRINHO-SIMOES
A1
Journal Article
in
ONCOGENE
2001
Expression of the E-cadherin-catenin complex in lung neuroendocrine tumours.
CE CLAVEL
Friedel Nollet
Geert Berx
S TEJPAR
B NAWORCKI-RABY
HH KAPLAN
Frans Van Roy
PL BIREMBAUT
A1
Journal Article
in
JOURNAL OF PATHOLOGY
2001
The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression
Geert Berx
Frans Van Roy
A1
Journal Article
in
BREAST CANCER RESEARCH
2001
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion.
Joke Comijn
Geert Berx
P VERMASSEN
K VERSCHUEREN
L VAN GRUNSVEN
Erik Bruyneel
Marcus Mareel
D HUYLEBROECK
Frans Van Roy
A1
Journal Article
in
MOLECULAR CELL
2001
1999
Distinct deleted regions on chromosome segment 16q23-24 associated with metastases in prostate cancer.
CD LI
Geert Berx
C LARSSON
G AUER
U ASPENBLAD
Y PAN
B SUNDELIN
P EKMAN
M NORDENSKJOLD
Frans Van Roy
et al.
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
1999
E-cadherin gene mutations provide a genetic basis for the phenotypic divergence of mixed gastric carcinomas.
JC MACHADO
P SOARES
F CARNEIRO
A ROCHA
S BECK
N BLIN
Geert Berx
M SOBRINHO-SIMOES
A1
Journal Article
in
LABORATORY INVESTIGATION
1999
Identification of eleven novel tumor-associated E-cadherin mutations
Karl-Friedrich Becker
Ulrike Reich
Christina Schott
Ingrid Becker
Geert Berx
Frans Van Roy
Heinz Höfler
A2
Journal Article
in
HUMAN MUTATION
1999
Neuroblastoma: from molecular cytogenetics to gene expression profiling
Jo Vandesompele
Nadine Van Roy
Geert Berx
D PLANTAZ
Anne De Paepe
Genevieve Laureys
Frans Van Roy
Franki Speleman
C3
Conference
1999
Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis.
Marc Van De Craen
Geert Berx
I VAN DEN BRANDE
Walther Fiers
Wim Declercq
Peter Vandenabeele
A1
Journal Article
in
FEBS LETTERS
1999
The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer.
Friedel Nollet
Geert Berx
Frans Van Roy
A2
Journal Article
in
Molecular Cell Biol. Res. Commun.
1999
1998
Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas.
Geert Berx
Friedel Nollet
Frans Van Roy
A1
Journal Article
in
CELL ADHESION AND COMMUNICATION
1998
Mutations of the human E-cadherin (CDH1) gene.
Geert Berx
KF BECKER
H HOFLER
Frans Van Roy
A1
Journal Article
in
HUMAN MUTATION
1998
1997
Allelic imbalance at the beta-catenin gene (CTNNB1 at 3p22-21.3) in various human tumor types.
Friedel Nollet
A VANDENBERG
AM KERSEMAEKERS
AM CLETONJANSEN
Geert Berx
AY VANDERVEEN
C EICHPERGER
I WIELAND
J DEGREVE
GJ LIEFERS
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF ONCOLOGY
1997
An efficient and reliable multiplex PCR-SSCP mutation analysis test applied to the human E-cadherin gene.
Geert Berx
Friedel Nollet
Kristin Strumane
Frans Van Roy
A1
Journal Article
in
HUMAN MUTATION
1997
E-cadherin gene alterations are rare events in thyroid tumors.
P SOARES
Geert Berx
Frans Van Roy
M SOBRINHO-SIMOES
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
1997
E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis.
CBJ VOS
AM CLETONJANSEN
Geert Berx
WJF DELEEUW
NT TERHAAR
Frans Van Roy
CJ CORNELISSE
JL PETERSE
MJ VANDEVIJVER
A1
Journal Article
in
BRITISH JOURNAL OF CANCER
1997
Simultaneous loss of E-cadherin and catenins in invasive lobular breast cancer and lobular carcinoma in situ.
WJF DELEEUW
Geert Berx
CBJ VOS
JL PETERSE
MJ VANDEVIJVER
S LITVINOV
Frans Van Roy
CJ CORNELISSE
AM CLETONJANSEN
A1
Journal Article
in
JOURNAL OF PATHOLOGY
1997
1996
Cadherin/catenin complex: A target for antiinvasive therapy?
Marcus Mareel
Geert Berx
Frans Van Roy
Marc Bracke
A1
Journal Article
in
JOURNAL OF CELLULAR BIOCHEMISTRY
1996
E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain.
Geert Berx
AM CLETONJANSEN
Kristin Strumane
WJF DELEEUW
Friedel Nollet
Frans Van Roy
C CORNELISSE
A1
Journal Article
in
ONCOGENE
1996
Genomic organization of the human beta-catenin gene (CTNNB1).
Friedel Nollet
Geert Berx
F MOLEMANS
Frans Van Roy
A1
Journal Article
in
GENOMICS
1996
Het menselijke E-cadherine gen : moleculaire karakterisering en analyse van genetische defecten in menselijke tumoren
Geert Berx
Walther Fiers
F. Van Roy
Dissertation
1996
The cadherin/catenin complex: a target for antiinvasive therapy ?
Marcus Mareel
Geert Berx
Frans Van Roy
Marc Bracke
A2
Journal Article
in
Journal Cellular Biochem., 61
1996
1995
Assignment of the human beta-catenin gene (CTNNB1) to 3p22->p21.3 by fluorescence in situ hybridization.
J VANHENGEL
F NOLLET
Geert Berx
Nadine Van Roy
Franki Speleman
Frans Van Roy
A1
Journal Article
in
CYTOGENETICS AND CELL GENETICS
1995
CLONING AND CHARACTERIZATION OF THE HUMAN INVASION SUPPRESSOR GENE E-CADHERIN (CDH1).
Geert Berx
K STAES
J VANHENGEL
F MOLEMANS
MJG BUSSEMAKERS
A VANBOKHOVEN
Frans Van Roy
A1
Journal Article
in
GENOMICS
1995
E-cadherin is a tumour invasion suppressor gene mutated in human lobular breast cancers.
Geert Berx
AM CLETONJANSEN
F NOLLET
WJF DELEEUW
MJ VANDEVIJVER
C CORNELISSE
Frans Van Roy
A1
Journal Article
in
EMBO JOURNAL
1995
ISOLATION AND CHARACTERIZATION OF A HUMAN PSEUDOGENE (CTNNAP1) FOR ALPHA-E-CATENIN (CTNNA1) - ASSIGNMENT OF THE PSEUDOGENE TO 5Q22 AND THE ALPHA-E-CATENIN GENE TO 5Q31.
F NOLLET
J VANHENGEL
Geert Berx
F MOLEMANS
Frans Van Roy
A1
Journal Article
in
GENOMICS
1995
Transition from the noninvasive to the invasive phenotype and loss of α-catenin in human colon cancer cells
Stefan Vermeulen
Erik Bruyneel
Marc Bracke
Georges De Bruyne
Krist'l M Vennekens
Kris Vleminckx
Geert Berx
Frans Van Roy
Marcus Mareel
A1
Journal Article
in
CANCER RESEARCH
1995
1992
The invasion suppressor role of E-cadherin
Frans Van Roy
K Vleminckx
Luc Vakaet
Geert Berx
Walther Fiers
Marcus Mareel
Bookchapter
in
Metastasis : basic research and its clinical applications
1992