Research Explorer

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Researcher

Freya Van Houtte

Awards & Distinctions

23 Results

2023

A human monoclonal antibody against HBsAg for the prevention and treatment of chronic HBV and HDV infection

Rani BurmFreya Van HoutteLieven VerhoyeAhmed Atef Ahmed Abouzeid MesalamS CiesekP RoingeardH WedemeyerGeert Leroux-RoelsPhilip Meuleman

A1 Journal Article in JHEP REPORTS

Novel prime-boost immune-based therapy inhibiting both hepatitis B and D virus infections

Rani BurmPanagiota MaraveliaGustaf AhlenSandra CiesekNoelia Caro PerezAnna PasettoStephan UrbanFreya Van HoutteLieven VerhoyeHeiner Wedemeyer et al.

A1 Journal Article in GUT

The phosphatidylserine receptor TIM1 promotes infection of enveloped hepatitis E virus.

Laura CorneillieIrma LemmensClaire MontpellierMartin FerriéKarin WeeningFreya Van HoutteXavier HanoulleLaurence CocquerelAli AmaraJan Tavernier et al.

U Journal Article in Cellular and molecular life sciences : CMLS

Virus-Host Protein Interaction Network of the Hepatitis E Virus ORF2-4 by Mammalian Two-Hybrid Assays.

Laura CorneillieIrma LemmensKarin WeeningAmse De MeyerFreya Van HoutteJan TavernierPhilip Meuleman

U Journal Article in Viruses

2021

A role for B cells to transmit hepatitis C virus infection

Isabelle DesombereFreya Van HoutteAliasghar Farhoudi MoghadamLieven VerhoyeCaroline BuysschaertYvonne GijbelsSibyl CouventW SwinnenHans Van VlierbergheAndré Elewaut et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2019

Hepatitis E virus prevalence in Flemish blood donors

Ann-Sofie VercouterFreya Van HoutteLieven VerhoyeIsabel González FraileLydia BlancoVeerle CompernollePhilip Meuleman

A1 Journal Article in JOURNAL OF VIRAL HEPATITIS

2018

Development and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeJonathan BallJean DubuissonSteven KH FoungArvind H PatelMats AA Persson et al.

A1 Journal Article in VIROLOGY

2017

A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo

Isabelle DesombereAhmed Atef Ahmed Abouzeid MesalamRichard A UrbanowiczFreya Van HoutteLieven VerhoyeZhen-Yong KeckAliasghar Farhoudi MoghadamKoen VercauterenKarin WeeningThomas F Baumert et al.

A1 Journal Article in ANTIVIRAL RESEARCH

Characterization of a novel monoclonal antibody targeting epitope II within hepatitis C virus E2 envelope glycoprotein

Philip MeulemanAhmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczFreya Van HoutteLieven VerhoyeZhen-Yong KeckAliasghar Farhoudi MoghadamKoen VercauterenKarin Weening et al.

Development and characterization of a human monoclonal antibody for prevention of HCV recurrence in liver transplant patients

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonKoen VercauterenAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan Ball et al.

2016

Characterization of a novel human monoclonal antibody targeting the hepatitis C virus envelope protein

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonKoen VercauterenAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan Ball et al.

Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus challenge

Isabelle DesombereSamira Fafi-KremerFreya Van HouttePatrick PessauxAliasghar Farhoudi MoghadamLaura HeydmannLieven VerhoyeSarah ColeJane A McKeatingGeert Leroux-Roels et al.

A1 Journal Article in HEPATOLOGY

2015

A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonKoen VercauterenAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeKarin WeeningMats Persson et al.

A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan BallGeert Leroux-Roels et al.

A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan BallGeert Leroux-Roels et al.

2010

Production, characterization and in vitro testing of HBcAg-specific VHH intrabodies

Benedikte SerruysFreya Van HoutteAliasghar Farhoudi MoghadamGeert Leroux-RoelsPeter Vanlandschoot

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

2009

Llama-Derived Single-Domain Intrabodies Inhibit Secretion of Hepatitis B Virions in Mice

Benedikte SerruysFreya Van HouttePhebe VerbruggheGeert Leroux-RoelsPeter Vanlandschoot

A1 Journal Article in HEPATOLOGY

2007

Contamination of a recombinant hepatitis B virus nucleocapsid preparation with a human B-cell activator

Peter VanlandschootFreya Van HoutteBenedikte SerruysGeert Leroux-Roels

A1 Journal Article in JOURNAL OF VIROLOGY

2006

Human hepatocytes secrete soluble CD14, a process not directly influenced by HBV and HCV infection

Philip MeulemanSophia SteyaertLouis LibbrechtSibyl CouventFreya Van HoutteFilip ClinckspoorBernard de HemptinneTania RoskamsPeter VanlandschootGeert Leroux-Roels

A1 Journal Article in CLINICA CHIMICA ACTA

2005

A temperature-dependent inhibitory activity of serum on the capacity of Saccharomyces cerevisiae-derived hepatitis B surface antigen to bind to monocytes

Peter VanlandschootFreya Van HoutteA ROOBROUCKF STELTERF GAVILANESGeert Leroux-Roels

A1 Journal Article in ARCHIVES OF VIROLOGY

Immunostimulatory potential of hepatitis B nucleocapsid preparations: lipopolysaccharide contamination should not be overlooked

Peter VanlandschootFreya Van HouttePeter UlrichtsJan TavernierGeert Leroux-Roels

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

The arginine-rich carboxy-terminal domain of the hepatitis B virus core protein mediates attachment of nucleocapsids to cell-surface-expressed heparan sulfate

Peter VanlandschootFreya Van HoutteBenedikte SerruysGeert Leroux-Roels

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

2003

Saccharomyces cerevisiae-derived HBsAg preparations differ in their attachment to monocytes, immune-suppressive potential, and T-cell immunogenicity

Peter VanlandschootFreya Van HoutteF HOEKR NIEUWLANDGeert Leroux-Roels

A1 Journal Article in JOURNAL OF MEDICAL VIROLOGY