Research Explorer

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Researcher

Freya Van Houtte

Awards & Distinctions

21 Results

2023

A human monoclonal antibody against HBsAg for the prevention and treatment of chronic HBV and HDV infection

Rani BurmFreya Van HoutteLieven VerhoyeAhmed Atef Ahmed Abouzeid MesalamS CiesekP RoingeardH WedemeyerGeert Leroux-RoelsPhilip Meuleman

A1 Journal Article in JHEP REPORTS

Novel prime-boost immune-based therapy inhibiting both hepatitis B and D virus infections

Rani BurmPanagiota MaraveliaGustaf AhlenSandra CiesekNoelia Caro PerezAnna PasettoStephan UrbanFreya Van HoutteLieven VerhoyeHeiner Wedemeyer et al.

A1 Journal Article in GUT

2021

A role for B cells to transmit hepatitis C virus infection

Isabelle DesombereFreya Van HoutteAliasghar Farhoudi MoghadamLieven VerhoyeCaroline BuysschaertYvonne GijbelsSibyl CouventW SwinnenHans Van VlierbergheAndré Elewaut et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2019

Hepatitis E virus prevalence in Flemish blood donors

Ann-Sofie VercouterFreya Van HoutteLieven VerhoyeIsabel González FraileLydia BlancoVeerle CompernollePhilip Meuleman

A1 Journal Article in JOURNAL OF VIRAL HEPATITIS

2018

Development and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeJonathan BallJean DubuissonSteven KH FoungArvind H PatelMats AA Persson et al.

A1 Journal Article in VIROLOGY

2017

A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo

Isabelle DesombereAhmed Atef Ahmed Abouzeid MesalamRichard A UrbanowiczFreya Van HoutteLieven VerhoyeZhen-Yong KeckAliasghar Farhoudi MoghadamKoen VercauterenKarin WeeningThomas F Baumert et al.

A1 Journal Article in ANTIVIRAL RESEARCH

Characterization of a novel monoclonal antibody targeting epitope II within hepatitis C virus E2 envelope glycoprotein

Philip MeulemanAhmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczFreya Van HoutteLieven VerhoyeZhen-Yong KeckAliasghar Farhoudi MoghadamKoen VercauterenKarin Weening et al.

Development and characterization of a human monoclonal antibody for prevention of HCV recurrence in liver transplant patients

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonKoen VercauterenAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan Ball et al.

2016

Characterization of a novel human monoclonal antibody targeting the hepatitis C virus envelope protein

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonKoen VercauterenAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan Ball et al.

Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus challenge

Isabelle DesombereSamira Fafi-KremerFreya Van HouttePatrick PessauxAliasghar Farhoudi MoghadamLaura HeydmannLieven VerhoyeSarah ColeJane A McKeatingGeert Leroux-Roels et al.

A1 Journal Article in HEPATOLOGY

2015

A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonKoen VercauterenAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeKarin WeeningMats Persson et al.

A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan BallGeert Leroux-Roels et al.

A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan BallGeert Leroux-Roels et al.

2010

Production, characterization and in vitro testing of HBcAg-specific VHH intrabodies

Benedikte SerruysFreya Van HoutteAliasghar Farhoudi MoghadamGeert Leroux-RoelsPeter Vanlandschoot

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

2009

Llama-Derived Single-Domain Intrabodies Inhibit Secretion of Hepatitis B Virions in Mice

Benedikte SerruysFreya Van HouttePhebe VerbruggheGeert Leroux-RoelsPeter Vanlandschoot

A1 Journal Article in HEPATOLOGY

2007

Contamination of a recombinant hepatitis B virus nucleocapsid preparation with a human B-cell activator

Peter VanlandschootFreya Van HoutteBenedikte SerruysGeert Leroux-Roels

A1 Journal Article in JOURNAL OF VIROLOGY

2006

Human hepatocytes secrete soluble CD14, a process not directly influenced by HBV and HCV infection

Philip MeulemanSophia SteyaertLouis LibbrechtSibyl CouventFreya Van HoutteFilip ClinckspoorBernard de HemptinneTania RoskamsPeter VanlandschootGeert Leroux-Roels

A1 Journal Article in CLINICA CHIMICA ACTA

2005

A temperature-dependent inhibitory activity of serum on the capacity of Saccharomyces cerevisiae-derived hepatitis B surface antigen to bind to monocytes

Peter VanlandschootFreya Van HoutteA ROOBROUCKF STELTERF GAVILANESGeert Leroux-Roels

A1 Journal Article in ARCHIVES OF VIROLOGY

Immunostimulatory potential of hepatitis B nucleocapsid preparations: lipopolysaccharide contamination should not be overlooked

Peter VanlandschootFreya Van HouttePeter UlrichtsJan TavernierGeert Leroux-Roels

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

The arginine-rich carboxy-terminal domain of the hepatitis B virus core protein mediates attachment of nucleocapsids to cell-surface-expressed heparan sulfate

Peter VanlandschootFreya Van HoutteBenedikte SerruysGeert Leroux-Roels

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

2003

Saccharomyces cerevisiae-derived HBsAg preparations differ in their attachment to monocytes, immune-suppressive potential, and T-cell immunogenicity

Peter VanlandschootFreya Van HoutteF HOEKR NIEUWLANDGeert Leroux-Roels

A1 Journal Article in JOURNAL OF MEDICAL VIROLOGY