Research Explorer

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Researcher

Freya Joris

Awards & Distinctions

10 Results

2020

Cationic amphiphilic drugs boost the lysosomal escape of small nucleic acid therapeutics in a nanocarrier-dependent manner

Thijs Van de VyverBram BogaertLynn De BackerFreya JorisRoberta GuagliardoJelter Van HoeckPieterjan MerckxSerge Van CalenberghSrinivas RamishettiDan Peer et al.

A1 Journal Article in ACS NANO

2018

Repurposing cationic amphiphilic drugs as adjuvants to induce lysosomal siRNA escape in nanogel transfected cells

Freya JorisLynn De BackerThijs Van de VyverChiara BastiancichStefaan De SmedtKoen Raemdonck

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2017

Choose your cell model wisely : the in vitro nanoneurotoxicity of differentially coated iron oxide nanoparticles for neural cell labeling

Freya JorisDaniel ValdepérezBeatriz PelazTianqiang WangShareen H. DoakBella B. ManshianStefaan J. SoenenWolfgang J. ParakStefaan De SmedtKoen Raemdonck

A1 Journal Article in ACTA BIOMATERIALIA

Small molecules convey big messages : boosting non-viral nucleic acid delivery with low molecular weight drugs

Freya JorisStefaan De SmedtKoen Raemdonck

A1 Journal Article in NANO TODAY

The repurposing of low molecular weight drugs to induce lysosomal release of siRNA and in vitro approaches to probe the toxicity of inorganic nanoparticles

Freya JorisStefaan De SmedtKoen Raemdonck

2016

Cytosolic delivery of nanolabels prevents their asymmetric inheritance and enables extended quantitative in vivo cell imaging

Ranhua XiongFreya JorisSayuan LiangRiet De RyckeSaskia LippensJo DemeesterAndre SkirtachKoen RaemdonckUwe HimmelreichStefaan De Smedt et al.

A1 Journal Article in NANO LETTERS

The impact of species and cell type on the nanosafety profile of iron oxide nanoparticles in neural cells

Freya JorisDaniel ValdepérezBeatriz PelazStefaan J SoenenBella B ManshianWolfgang J ParakStefaan De SmedtKoen Raemdonck

A1 Journal Article in JOURNAL OF NANOBIOTECHNOLOGY

2015

Efficient delivery of quantum dots in live cells by gold nanoparticle mediated photoporation

Ranhua XiongFreya JorisIne De CockJo DemeesterStefaan De SmedtAndre SkirtachKevin Braeckmans

2014

Exploiting intrinsic nanoparticle toxicity: the pros and cons of nanoparticle-induced autophagy in biomedical research

Karen PeynshaertBella Barjouhi ManshianFreya JorisKevin BraeckmansStefaan De SmedtJo DemeesterStefaan Soenen

A1 Journal Article in CHEMICAL REVIEWS

2013

Assessing nanoparticle toxicity in cell-based assays : influence of cell culture parameters and optimized models for bridging the in vitro-in vivo gap

Freya JorisBella B ManshianKaren PeynshaertStefaan De SmedtKevin BraeckmansStefaan Soenen

A1 Journal Article in CHEMICAL SOCIETY REVIEWS