Research Explorer

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Researcher

Frederick Verbeke

Awards & Distinctions

49 Results

2023

C-reactive protein interacts with amphotericin B liposomes and its potential clinical consequences

Joris DelangheJonas HimpeJerina BoelensDominique BenoitBram GadeyneMarijn SpeeckaertFrederick Verbeke

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Environment-functionality-cost balance of an analytical reagent

Hannah HirmzFrederick VerbekeBartosz WielgomasChristophe FurmanEmmanuelle LipkaBart De SpiegeleerEvelien Wynendaele

A1 Journal Article in SUSTAINABLE CHEMISTRY AND PHARMACY

2022

A bioanalytical screening method for Enterococcus faecalis RNPP-type quorum sensing peptides in murine feces

Frederick VerbekeNathan DebunneYorick JanssensBart De SpiegeleerEvelien Wynendaele

A1 Journal Article in BIOANALYSIS

A fit-for-purpose LC-MS/MS method for the analysis of selected Streptococcal quorum sensing peptides in human saliva

Frederick VerbekeKevin Van der borghtAnton De SpiegeleerNathan DebunneYorick JanssensEvelien WynendaeleBart De Spiegeleer

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Exploring the in-vivo role of quorum sensing peptides : preclinical and bioanalytical contributions

Frederick VerbekeBart De SpiegeleerEvelien Wynendaele

The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia

Anton De SpiegeleerEvelien WynendaeleAmélie DescampsNathan DebunneBart BraeckmanMarjan De MeyJulie CoudenysLiesbeth CrombezFrederick VerbekeYorick Janssens et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL MEDICINE

The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice : a new factor in the host-microbiome interaction

Evelien WynendaeleNathan DebunneYorick JanssensAnton De SpiegeleerFrederick VerbekeLiesa TackSophie Van WeldenEvy GoossensDaniel KnappeRalf Hoffmann et al.

A1 Journal Article in BMC BIOLOGY

2021

Faecal microbiota transplants : why do we not consider them as Advanced Therapy Medicinal Products?

Frederick VerbekeBart De Spiegeleer

A1 Journal Article in UNITED EUROPEAN GASTROENTEROLOGY JOURNAL

Purpura fulminans : how varicella zoster can result in acquired protein S deficiency

Frederick VerbekeBram De WildeJef WillemsKatrien Devreese

Editorial material

2020

A clinician’s perspective on yellow fever vaccine-associated neurotropic disease

Elien LecomteGuy LaureysFrederick VerbekeCristina Domingo CarrascoMarjan Van EsbroeckRalph Huits

A1 Journal Article in JOURNAL OF TRAVEL MEDICINE

LC-MS compatible antiadsorption diluent for peptide analysis

Frederick VerbekeNathalie BrackeNathan DebunneEvelien WynendaeleBart De Spiegeleer

A1 Journal Article in ANALYTICAL CHEMISTRY

MEK1/2 inhibition in murine heart and aorta after oral administration of refametinib supplemented drinking water

Felke SteijnsNathalie BrackeMarjolijn RenardJulie De BackerPatrick SipsNathan DebunneEvelien WynendaeleFrederick VerbekeBart De SpiegeleerLaurence Campens

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Quorum sensing peptides and their interactions with the host

Evelien WynendaeleNathan DebunneFrederick VerbekeYorick JanssensAnton De SpiegeleerBart De Spiegeleer

Bookchapter in Quorum sensing : microbial rules of life

2019

Biological characterisation of somatropin-derived cryptic peptides

Liesa TackNathalie BrackeFrederick VerbekeEvelien WynendaeleEwald PauwelsAlex MaesChristophe Van de WieleMike SathekgeBart De Spiegeleer

A1 Journal Article in INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS

Hot-melt preparation of a non-biodegradable peptide implant : a proof of principle

Matthias D'HondtFrederick VerbekePieter WuytensAndre SkirtachBart De SpiegeleerEvelien Wynendaele

A1 Journal Article in PROTEIN AND PEPTIDE LETTERS

2018

Analysis of iodinated quorum sensing peptides by LC-UV/ESI ion trap mass spectrometry

Yorick JanssensFrederick VerbekeNathan DebunneEvelien WynendaeleKathelijne PeremansBart De Spiegeleer

A1 Journal Article in JOURNAL OF PHARMACEUTICAL ANALYSIS

Chromatography of quorum sensing peptides : an important functional class of the bacterial peptidome

Nathan DebunneFrederick VerbekeYorick JanssensEvelien WynendaeleBart De Spiegeleer

A1 Journal Article in CHROMATOGRAPHIA

Detection and quantification of Enterococcus faecalis RNPP-type quorum sensing peptides in bacterial culture media by UHPLC-MS

Frederick VerbekeNathan DebunneYorick JanssensLiesa TackEvelien WynendaelePetra RigoleTom CoenyeBart De Spiegeleer

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Disbiome database : linking the microbiome to disease

Yorick JanssensJoachim NielandtAntoon BronselaerNathan DebunneFrederick VerbekeEvelien WynendaeleFilip Van ImmerseelYves-Paul VandewynckelGuy De TréBart De Spiegeleer

A1 Journal Article in BMC MICROBIOLOGY

Quality of isotopically labelled internal standards for peptide quantification

Nathan DebunneFrederick VerbekeYorick JanssensLiesa TackEvelien WynendaeleBart De Spiegeleer

Screening of quorum sensing peptides for biological effects in neuronal cells

Yorick JanssensEvelien WynendaeleFrederick VerbekeNathan DebunneBert GevaertKurt AudenaertChristophe Van De WieleBart De Spiegeleer

A1 Journal Article in PEPTIDES

2017

Analytics in microbiome : investigating quorum sensing peptides

Nathan DebunneFrederick VerbekeEvelien WynendaeleYorick JanssensBart De Spiegeleer

Faecal microbiota transplantation : a regulatory hurdle?

Frederick VerbekeYorick JanssensEvelien WynendaeleBart De Spiegeleer

Editorial material

In vitro functional quality characterization of NOTA-modified somatropins

Nathalie BrackeHan YaoEvelien WynendaeleFrederick VerbekeXiaolong XuBert GevaertAlex MaesChristophe Van De WieleMike SathekgeSarah De Saeger et al.

A1 Journal Article in ANALYTICAL CHEMISTRY

Peptides as quorum sensing molecules : measurement techniques and obtained levels in vitro and in vivo

Frederick VerbekeSeverine De CraemerNathan DebunneYorick JanssensEvelien WynendaeleChristophe Van de WieleBart De Spiegeleer

A1 Journal Article in FRONTIERS IN NEUROSCIENCE

2016

Bacterial quorum sensing peptides and the inter-kingdom communication with human cancer cells

Frederick VerbekeEvelien WynendaeleYorick JanssensBart De Spiegeleer

Fish hydrolysates : a regulatory perspective of bioactive peptides

Bert GevaertLieselotte VeryserFrederick VerbekeEvelien WynendaeleBart De Spiegeleer

A1 Journal Article in PROTEIN AND PEPTIDE LETTERS

Implementation of UHPLC-single quad MS platform : the next level transforming pharmaceutical quality control laboratories

Evelien WynendaeleBert GevaertLieselotte VeryserXiaolong XuFrederick VerbekeBart De Spiegeleer

Pre-clinical pharmacokinetics of selected quorum sensing peptides

Yorick JanssensEvelien WynendaeleFrederick VerbekeBart De Spiegeleer

Quality control of cationic cell-penetrating peptides

Sofie StalmansBert GevaertFrederick VerbekeMatthias D'HondtNathalie BrackeEvelien WynendaeleBart De Spiegeleer

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Quorum sensing peptides: the missing link between microbiome and disease?

Evelien WynendaeleFrederick VerbekeYorick JanssensNathan DebunneBart De Spiegeleer

The effects of quorum sensing peptides on colon cancer cells: implications for the role of the gut microbiome

Yorick JanssensEvelien WynendaeleFrederick VerbekeAn HendrixOlivier De WeverMarc BrackeBart De Spiegeleer

The human microbiota in health and disease: the role of quorum sensing peptides

Evelien WynendaeleFrederick VerbekeYorick JanssensBart De Spiegeleer

2015

Communication of quorum sensing peptides with breast cancer cells

Frederick VerbekeEvelien WynendaeleMarianne LauwersAn HendrixChristian BurvenichOlivier De WeverMarc BrackeBart De Spiegeleer

Crosstalk between the microbiome and cancer cells by quorum sensing peptides

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

A1 Journal Article in PEPTIDES

Exploring the chemical space of quorum sensing peptides

Evelien WynendaeleBert GevaertSofie StalmansFrederick VerbekeBart De Spiegeleer

A1 Journal Article in BIOPOLYMERS

Quality evaluation of synthetic quorum sensing peptides used in R&D

Frederick VerbekeEvelien WynendaeleSarah BraetMatthias D'HondtBart De Spiegeleer

A2 Journal Article in JOURNAL OF PHARMACEUTICAL ANALYSIS

Quorum sensing peptides selectively penetrate the blood-brain barrier

Evelien WynendaeleFrederick VerbekeSofie StalmansBert GevaertYorick JanssensChristophe Van De WieleKathelijne PeremansChristian BurvenichBart De Spiegeleer

A1 Journal Article in PLOS ONE

The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro

Bart De SpiegeleerFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeEvelien Wynendaele

A1 Journal Article in PLOS ONE

2014

Are plant N-alkylamide cosmenutriceuticals also active in the central nervous system?

Lieselotte VeryserEvelien WynendaeleLien TaevernierFrederick VerbekeTanmayee JoshiPratima TatkeBart De Spiegeleer

Crosstalk between mammalian cells and the microbiome through quorum sensing peptides, influencing cancer metastasis

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

Derringer desirability and kinetic plot LC-column comparison approach for MS-compatible lipopeptide analysis

Matthias D'HondtFrederick VerbekeSofie StalmansBert GevaertEvelien WynendaeleBart De Spiegeleer

A2 Journal Article in JOURNAL OF PHARMACEUTICAL ANALYSIS

How does the human microbiome affect cancer outcome?

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

N-alkylamides : from plant to brain

Lieselotte VeryserEvelien WynendaeleLien TaevernierFrederick VerbekeTanmayee JoshiPratima TatkeBart De Spiegeleer

A2 Journal Article in FUNCTIONAL FOODS IN HEALTH AND DISEASE

Quorum sensing peptides: missing link between microbiome and health?

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

Related impurities in peptide medicines

Matthias D'HondtNathalie BrackeLien TaevernierBert GevaertFrederick VerbekeEvelien WynendaeleBart De Spiegeleer

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

2013

Quorumpeps database : chemical space, microbial origin and functionality of quorum sensing peptides

Evelien WynendaeleAntoon BronselaerJoachim NielandtMatthias D'HondtSofie StalmansNathalie BrackeFrederick VerbekeChristophe Van De WieleGuy De TréBart De Spiegeleer

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Synthesis and evaluation of 5'-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors

Kiran TotiFrederick VerbekeMartijn RisseeuwVladimir FrecerHélène Munier-LehmannSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

2012

5,5'-Bis-substituted 2'-deoxyuridines as possible M. tuberculosis thymidylate kinase inhibitors

Kiran TotiFrederick VerbekeMartijn RisseeuwHélène Munier-LehmannSerge Van Calenbergh