Research Explorer

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Researcher

Frauke Vanden Meerschaut

Publications & Research Data

Awards & Distinctions

57 Results

2025

Beheer van genetische risico’s bij behandelingen met donorsperma in België

Dorian AccoeGuido PenningsKelly TillemanFrauke Vanden MeerschautSandra JanssensHeidi Mertes

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

2024

Aligning genotyping and copy number data in single trophectoderm biopsies for aneuploidy prediction : uncovering incomplete concordance

Lisa De WitteMachteld BaetensKelly TillemanFrauke Vanden MeerschautSandra JanssensAriane Van TongerlooVirginie SzymczakDominic StoopAnnelies DheedeneSofie Symoens et al.

A1 Journal Article in HUMAN REPRODUCTION OPEN

High rate of detected variants in male PLCZ1 and ACTL7A genes causing failed fertilization after ICSI

Arantxa Cardona BarberánRamesh Reddy GuggillaCora ColenbierEmma Van der VeldenAndrei RybouchkinDominic StoopLuc LeybaertPaul CouckeSofie SymoensAnnekatrien Boel et al.

A1 Journal Article in HUMAN REPRODUCTION OPEN

Implicit bias in diagnosing mosaicism amongst preimplantation genetic testing providers : results from a multicenter study of 36 395 blastocysts

Mina PopovicLorena BorotAline R. LorenzonAna Luiza Rossi de Castro LopesDenny SakkasBelen LledoRuth MoralesJose Antonio OrtizNikolaos PolyzosMonica Parriego et al.

A1 Journal Article in HUMAN REPRODUCTION

Managing risks for genetic conditions in donor sperm treatment : current practices in Belgian fertility clinics

Dorian AccoeGuido PenningsKelly TillemanFrauke Vanden MeerschautSandra JanssensHeidi Mertes

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

The ethics of disclosing reported conditions in donor-conceived offspring to recipients of the same donor

Dorian AccoeGuido PenningsSandra JanssensFrauke Vanden MeerschautHeidi Mertes

2023

Assisted oocyte activation does not overcome recurrent embryo developmental problems

Arantxa Cardona BarberánDavina BonteAnnekatrien BoelVanessa ThysRuth ParedisFemke MachtelinckxPetra De SutterIlse De CrooLuc LeybaertDominic Stoop et al.

A1 Journal Article in HUMAN REPRODUCTION

Incidence of and indications for sperm donor restriction-analysis of patients continuing treatment : a retrospective single-centre study

Eva VanbelleghemVanessa MuyshondRoos ColmanFrauke Vanden MeerschautDominic StoopSandra JanssensKelly Tilleman

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

Monogenic and digenic variants in male PLCZ1, ACTL7A and ACTL9 genes cause fertilization failure after ICSI

Arantxa Cardona BarberánAnnekatrien BoelCora ColenbierEmma Van der VeldenDominic StoopPaul CouckeFrauke Vanden MeerschautBjörn Heindryckx

2022

Fertilization failure after human ICSI and the clinical potential of PLCZ1

Arantxa Cardona BarberánAnnekatrien BoelFrauke Vanden MeerschautDominic StoopBjörn Heindryckx

A1 Journal Article in REPRODUCTION

GENType : all-in-one preimplantation genetic testing by pedigree haplotyping and copy number profiling suitable for third-party reproduction

Lisa De WitteLennart RamanMachteld BaetensAndries De KokerNico CallewaertSofie SymoensKelly TillemanFrauke Vanden MeerschautAnnelies DheedeneBjörn Menten

A1 Journal Article in HUMAN REPRODUCTION

Human germline nuclear transfer to overcome mitochondrial disease and failed fertilization after ICSI

Maoxing TangAnnekatrien BoelNoemi CastelluccioArantxa Cardona BarberánAntonia ChristodoulakiBieke BekaertMina PopovicFrauke Vanden MeerschautPetra De SutterBjörn Menten et al.

A1 Journal Article in JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Screening of chlamydia trachomatis in non-partner donors : situation of stored donations and proposal for periodic screening

Stijn Van LandeghemKelly TillemanFrauke Vanden MeerschautElizaveta Padalko

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

Treatment options to overcome impaired fertilization and embryonic development caused by an oocyte-related deficiency in the Patl2-/- mouse model

Arantxa Cardona BarberánAntonia ChristodoulakiJosefien GoethalsVanessa ThysFrauke Vanden MeerschautC. ArnoultDominic StoopAnnekatrien BoelBjörn Heindryckx

2021

Impact of ARTs on oncological outcomes in young breast cancer survivors

M CondorelliM De VosS Lie FongC AutinA DelvigneFrauke Vanden MeerschautC WynsR ImbertC CheruyJ Bouziotis et al.

A1 Journal Article in HUMAN REPRODUCTION

2020

Assessment of molecular determinants underlying recurrent embryo developmental arrest and value of assisted oocyte activation as a treatment option

Annekatrien BoelDavina BonteArantxa Cardona BarberánVanessa ThysDominic StoopPetra De SutterPaul CouckeFrauke Vanden MeerschautBjörn Heindryckx

Diagnosis and treatment of male infertility-related fertilization failure

Arantxa Cardona BarberánAnnekatrien BoelFrauke Vanden MeerschautDominic StoopBjörn Heindryckx

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Germline nuclear transfer to overcome mitochondrial disease and female infertility

Maoxing TangAnnekatrien BoelRamesh Reddy GuggillaBieke BekaertPetra De SutterBjörn MentenFrauke Vanden MeerschautDominic StoopPaul CouckeBjörn Heindryckx

2019

Assisted oocyte activation significantly increases fertilization and pregnancy outcome in patients with low and total failed fertilization after intracytoplasmic sperm injection : a 17-year retrospective study

Davina BonteMinerva Ferrer BuitragoLien DhaenensMina PopovicVanessa ThysIlse De CrooStefanie De GheselleNathalie SteyaertAnnekatrien BoelFrauke Vanden Meerschaut et al.

A1 Journal Article in FERTILITY AND STERILITY

2018

Human oocyte calcium analysis predicts the response to assisted oocyte activation in patients experiencing fertilization failure after ICSI

Minerva Ferrer BuitragoLien DhaenensYuechao LuDavina BonteFrauke Vanden MeerschautPetra De SutterLuc LeybaertBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION

2017

Evaluating oocyte activation potential of sperm using calcium pattern analysis

Björn HeindryckxMinerva Ferrer BuitragoFrauke Vanden MeerschautPetra De Sutter

2016

Effect of two assisted oocyte activation protocols used to overcome fertilization failure on the activation potential and calcium releasing pattern

Dimitra NikiforakiFrauke Vanden MeerschautChloë De RooYuechao LuMinerva Ferrer BuitragoPetra De SutterBjörn Heindryckx

A1 Journal Article in FERTILITY AND STERILITY

2015

Human oocyte calcium analysis (HOCA) : a novel test for sperm oocyte-activation potential

Minerva Ferrer BuitragoSylvie LiermanFrauke Vanden MeerschautDimitra NikiforakiEtienne Van den AbbeelMargot Van der JeughtPetra De SutterBjörn Heindryckx

2014

Assisted oocyte activation following ICSI fertilization failure

Frauke Vanden MeerschautDimitra NikiforakiBjörn HeindryckxPetra De Sutter

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

Effect of ionomycin and calcium in the culture medium on the calcium releasing pattern of mouse oocytes and their subsequent embryonic development

Yuechao LuDimitra NikiforakiFrauke Vanden MeerschautJitesh NeupaneChen QianWinnok De VosJP OzilTom DerooPetra De SutterBjörn Heindryckx

First-trimester Down syndrome screening after assisted conception

Frauke Vanden MeerschautClaude GiorgettiPetra De Sutter

A1 Journal Article in FERTILITY AND STERILITY

Language development of children born following intracytoplasmic sperm injection (ICSI) combined with assisted oocyte activation (AOA)

Evelien D'haeseleerFrauke Vanden MeerschautKim BettensAnke LuytenHannelore GyselsYlenia ThienpontGriet De WitteBjörn HeindryckxAnn OostraHerbert Roeyers et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF LANGUAGE & COMMUNICATION DISORDERS

Neonatal and neurodevelopmental outcome of children aged 3-10 years born following assisted oocyte activation

Frauke Vanden MeerschautEvelien D'haeseleerHannelore GyselsYlenia ThienpontGrietje DewitteBjörn HeindryckxAnn OostraHerbert RoeyersKristiane Van LierdePetra De Sutter

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

Oocyte cryopreservation and in vitro culture affect calcium signalling during human fertilization

Dimitra NikiforakiFrauke Vanden MeerschautChen QianIlse De CrooYuechao LuTom DerooEtienne Van den AbbeelBjörn HeindryckxPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

Sperm involved in recurrent partial hydatidiform moles cannot induce the normal pattern of calcium oscillations

Dimitra NikiforakiFrauke Vanden MeerschautStefanie De GheselleChen QianEtienne Van den AbbeelWinnok De VosTom DerooPetra De SutterBjörn Heindryckx

A1 Journal Article in FERTILITY AND STERILITY

2013

Analysis of calcium oscillations pattern triggered by human sperm showing failed or low fertilization

Björn HeindryckxDimitra NikiforakiLeen CaluwaertsFrauke Vanden MeerschautTom DerooPetra De Sutter

Assisted oocyte activation overcomes fertilization failure in globozoospermic patients regardless of the DPY19L2 status

P KuentzFrauke Vanden MeerschautE ElInatiMH Nasr-EsfahaniT GurganN IqbalF Carré-PigeonF BrugnonSA GitlinJV de la Calle et al.

A1 Journal Article in HUMAN REPRODUCTION

Comparison of pre- and post-implantation development following the application of three artificial activating stimuli in a mouse model with round-headed sperm cells deficient for oocyte activation

Frauke Vanden MeerschautDimitra NikiforakiChloë De RooSylvie LiermanChen QianT Schmitt-JohnPetra De SutterBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION

De taalontwikkeling van kinderen geboren na kunstmatige bevruchting met geassisteerde eicelactivatie, een pilootstudie

Evelien D'haeseleerFrauke Vanden MeerschautKim BettensAnke LuytenHannelore GyselsYlenia ThienpontGriet De WitteBjörn HeindryckxAnn OostraHerbert Roeyers et al.

A2 Journal Article in LOGOPEDIE (HERENTALS)

Diagnostic and prognostic value of calcium oscillatory pattern analysis for patients with ICSI fertilization failure

Frauke Vanden MeerschautLuc LeybaertDimitra NikiforakiChen QianBjörn HeindryckxPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

Efficiency and safety of assisted oocyte activation (AOA) in the mouse and the human

Frauke Vanden MeerschautPetra De SutterBjörn Heindryckx

Evaluation of calcium machinery in a meiosis defect mouse model

Yuechao LuDimitra NikiforakiFrauke Vanden MeerschautJitesh NeupaneWinnok De VosSylvie LiermanTom DerooBjörn HeindryckxPetra De Sutter

Multivariate analysis identifies the estradiol level at ovulation triggering as an independent predictor of the first trimester pregnancy-associated plasma protein-A level in IVF/ICSI pregnancies

Claude GiorgettiFrauke Vanden MeerschautChloë De RooOdile SaunierEdwin QuarelloDominique HairionGuillaume PenarandaVéronique Chabert-OrsiniPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

Prospective, randomized trial on the effect of laser assisted hatching on frozen-thawed embryo transfer cycles

Ilse De CrooFrauke Vanden MeerschautStijn VansteelandtEtienne Van den AbbeelPetra De Sutter

Regulation of inositol 1,4,5-trisphosphate receptor during human oocyte maturation and fertilization

Dimitra NikiforakiLiesbeth VossaertFrauke Vanden MeerschautChen QianYuechao LuJ ParysWinnok De VosDieter DeforceTom DerooEtienne Van den Abbeel et al.

2012

Assisted oocyte activation is not beneficial for all patients with a suspected oocyte-related activation deficiency

Frauke Vanden MeerschautDimitra NikiforakiStefanie De GheselleValerie DullaertsEtienne Van den AbbeelJan GerrisBjörn HeindryckxPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

Calcium response during human oocyte activation : the effect of in vitro maturation and cryopreservation

Dimitra NikiforakiFrauke Vanden MeerschautChen QianEtienne Van den AbbeelBjörn HeindryckxPetra De Sutter

Calcium response during human oocyte activation : the effect of in vitro maturation and cryopreservation

Dimitra NikiforakiFrauke Vanden MeerschautChen QianEtienne Van den AbbeelBjörn HeindryckxPetra De Sutter

Calciumpatroonanalyse tijdens eicelrijping en na toepassing van geassisteerde eicelactivatie

Chloë De RooDimitra NikiforakiFrauke Vanden MeerschautYuechao LuSylvie LiermanChen QianBjörn HeindryckxPetra De Sutter

Comparison of the effect of ionomycin versus calcimycin on the intracellular calcium level in mouse and human oocytes and subsequent oocyte activation

Frauke Vanden MeerschautChloë De RooDimitra NikiforakiSylvie LiermanChen QianBjörn HeindryckxPetra De Sutter

Diagnostic calcium pattern analysis in mouse oocytes for patients with previous fertilization failure following ICSI

Frauke Vanden MeerschautDimitra NikiforakiChen QianBjörn HeindryckxLuc LeybaertPetra De Sutter

Genetic aspects and clinical outcomes of globozoospermia

E. ElInatiP. KuentzC. RedinFrauke Vanden MeerschautM. Nasr-EsfahaniT. GurganN. LouanjliN. IqbalF. Carre PigeonH. Gourabi et al.

Globozoospermia is mainly due to DPY19L2 deletion via non-allelic homologous recombination involving two recombination hotspots

Elias EllnatiPaul KuentzClaire RedinSara JaberFrauke Vanden MeerschautJoelle MakarianIsabelle KoscinskiMohammad H Nasr-EsfahaniAygul DemirolTimur Gurgan et al.

A1 Journal Article in HUMAN MOLECULAR GENETICS

Influence of human sperm motility and cryopreservation on the oocyte activating factor phospholipase C zeta

Björn HeindryckxDimitra NikiforakiFrauke Vanden MeerschautWinnok De VosSylvie LiermanPetra De Sutter

Neonatal and developmental outcome of children born following assisted oocyte activation (AOA)

Frauke Vanden MeerschautEvelien D'haeseleerHerbert RoeyersAnn OostraKristiane Van LierdePetra De Sutter

The effect of oocyte aging on the calcium oscillations and embryo development of in vivo and in vitro matured oocytes

Yuechao LuDimitra NikiforakiFrauke Vanden MeerschautJitesh NeupaneBjörn HeindryckxPetra De Sutter

2011

Calcium releasing ability of human sperm with deficient oocyte activation capacity

Dimitra NikiforakiFrauke Vanden MeerschautChen QianDieter DeforceEsther Van den AbbeelK CowardJ ParringtonLuc LeybaertBjörn HeindryckxPetra De Sutter

Phospholipase Cβ1 as a possible oocyte factor responsible for successful oocyte activation and embryo development

Frauke Vanden MeerschautBjörn HeindryckxChen QianDieter DeforceLuc LeybaertPetra De Sutter

2010

Anonieme donatie van gameten: de maatstaf?

Frauke Vanden MeerschautPetra De Sutter

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Comparison of three artificial activating stimuli using a mouse model deficient for oocyte activation

Björn HeindryckxFrauke Vanden MeerschautSylvie LiermanChen QianThomas O'LearyJan GerrisPetra De Sutter

Efficiency of assisted oocyte activation (AOA) in patients with an oocyte factor deficiency diagnosed by the mouse oocyte activation test (MOAT)

Frauke Vanden MeerschautBjörn HeindryckxStefanie De GheselleValerie DullaertsJan GerrisPetra De Sutter

2008

PCOS in lesbian and heterosexual women treated with artificial donor insemination

Petra De SutterTINEKE DUTREFrauke Vanden MeerschautIsabelle StuyverGEORGES VAN MAELEMarc Dhont

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE