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Researcher
Francis Impens
Profile
Projects
Publications
Activities
106
Results
2023
Cells responding to closely related cholesterol-dependent cytolysins release extracellular vesicles with a common proteomic content including membrane repair proteins
Rupert Mayer
Francis Impens
A1
Journal Article
in
TOXINS
2023
Complementary peptides represent a credible alternative to agrochemicals by activating translation of targeted proteins
Francis Impens
Delphi Van Haver
Kris Gevaert
A1
Journal Article
in
NATURE COMMUNICATIONS
2023
Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space
Riet De Rycke
Gert Van Isterdael
Francis Impens
A1
Journal Article
in
NATURE CELL BIOLOGY
2023
2022
A cytosolic disulfide bridge-supported dimerization is crucial for stability and cellular distribution of Coxsackievirus B3 protein 3A
Fabien Henri Thery
Francis Impens
A1
Journal Article
in
FEBS JOURNAL
2022
A strong cation exchange chromatography protocol for examining N-terminal proteoforms
Annelies Bogaert
Evy Timmerman
An Staes
Francis Impens
Kris Gevaert
Bookchapter
in
Yeast functional genomics : methods and protocols
2022
An unexpected encounter : respiratory syncytial virus nonstructural protein 1 interacts with mediator subunit MED25
Tessa Van Royen
Koen Sedeyn
Georgios Moschonas
Wendy Toussaint
Delphi Van Haver
Francis Impens
Sven Eyckerman
Irma Lemmens
Jan Tavernier
Bert Schepens
Xavier Saelens
A1
Journal Article
in
JOURNAL OF VIROLOGY
2022
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity
Francis Impens
A1
Journal Article
in
ALZHEIMERS & DEMENTIA
2022
Characterization of RBPome in oxidative stress conditions
Zhicheng Zhang
Evy Timmerman
Francis Impens
Frank Van Breusegem
Bookchapter
in
Reactive oxygen species in plants : methods and protocols
2022
Characterization of the Arabidopsis RBPome in oxidative stress conditions
Zhicheng Zhang
Evy Timmerman
Francis Impens
Frank Van Breusegem
C3
Conference
2022
Functional characterization of RNF213 as newly discovered ISG15 sensor during infection
Lia Martina
Francis Impens
Sven Eyckerman
Dissertation
2022
How tech-savvy employees make the difference in core facilities : recognizing core facility expertise with dedicated career tracks
Saskia Lippens
Dominique Audenaert
Alexander Botzki
Stefaan Derveaux
Bart Ghesquière
Geert Goeminne
Jurgen Haustraete
Francis Impens
Jochen Lamote
Niels Vandamme
Gert Van Isterdael
Geert Van Minnebruggen
Editorial material
2022
Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes
Rupert Mayer
Rein Verbeke
Caroline Asselman
Ilke Aernout
Adillah Gul
Denzel Eggermont
Katie Boucher
Fabien Henri Thery
Teresa Maia
Hans Demol
Ralf Gabriels
Lennart Martens
Stefaan De Smedt
Bart Vandekerckhove
Ine Lentacker
Francis Impens
A1
Journal Article
in
NATURE COMMUNICATIONS
2022
Moyamoya disease emerging as an immune-related angiopathy
Caroline Asselman
Dimitri Hemelsoet
Denzel Eggermont
Bart Dermaut
Francis Impens
A1
Journal Article
in
TRENDS IN MOLECULAR MEDICINE
2022
Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division
Francis Impens
A1
Journal Article
in
NATURE COMMUNICATIONS
2022
Proteome-wide cellular thermal shift assay reveals unexpected cross-talk between brassinosteroid and auxin signaling
Qing Lu
Yonghong Zhang
Xiangyu Xu
Jarne Pauwels
Qian Ma
Wim Dejonghe
Brigitte Van De Cotte
Francis Impens
Kris Gevaert
Ive De Smet
Eugenia Russinova
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2022
Proteomics-based characterization of ISG15 signaling in host defense mechanisms against microbial infection
Fabien Henri Thery
Francis Impens
Sven Eyckerman
Dissertation
2022
Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials
Joline Ingels
Laurenz De Cock
Rupert Mayer
Pam Devreker
Karin Weening
Kelly Heyns
Stijn De Munter
Melissa Pille
Lore Billiet
Glenn Goetgeluk
Sarah Bonte
Hanne Jansen
Sandra Van Lint
Georges Leclercq
Tom Taghon
Björn Menten
Karim Vermaelen
Francis Impens
Bart Vandekerckhove
A1
Journal Article
in
CYTOTHERAPY
2022
The final maturation state of β-actin involves N-terminal acetylation by NAA80, not N-terminal arginylation by ATE1
Evy Timmerman
Francis Impens
Kris Gevaert
A1
Journal Article
in
JOURNAL OF MOLECULAR BIOLOGY
2022
2021
ATP13A3 is a major component of the enigmatic mammalian polyamine transport system
Rupert Mayer
Francis Impens
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2021
Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis
Francis Impens
Delphi Van Haver
A1
Journal Article
in
NATURE
2021
Identification of the MuRF1 skeletal muscle ubiquitylome through quantitative proteomics
Delphi Van Haver
Teresa Maia
Francis Impens
A2
Journal Article
in
FUNCTION (OXFORD)
2021
Immunopeptidomics for next-generation bacterial vaccine development
Rupert Mayer
Francis Impens
A1
Journal Article
in
TRENDS IN MICROBIOLOGY
2021
Loss-of-function mutations in TRAF7 and KLF4 cooperatively activate RAS-like GTPase signaling and promote meningioma development
Teresa Maia
Delphi Van Haver
Sven Eyckerman
Francis Impens
A1
Journal Article
in
CANCER RESEARCH
2021
Mechanisms of congenital heart disease caused by NAA15 haploinsufficiency
Francis Impens
Petra Van Damme
Delphi Van Haver
Evy Timmerman
Kris Gevaert
A1
Journal Article
in
CIRCULATION RESEARCH
2021
Proteome profiling of RNF213 depleted cells reveals nitric oxide regulator DDAH1 antilisterial activity
Lia Martina
Caroline Asselman
Fabien Henri Thery
Katie Boucher
Louis Delhaye
Teresa Maia
Bart Dermaut
Sven Eyckerman
Francis Impens
A1
Journal Article
in
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
2021
Proteomics mapping of the ISGylation landscape in innate immunity
Fabien Henri Thery
Denzel Eggermont
Francis Impens
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2021
Quality standards in proteomics research facilities : common standards and quality procedures are essential for proteomics facilities and their users
Teresa Maia
Francis Impens
Editorial material
2021
Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity
Fabien Henri Thery
Lia Martina
Caroline Asselman
Heidi Repo
Koen Sedeyn
Georgios Moschonas
Denzel Eggermont
Delphine De Sutter
Katie Boucher
Tino Hochepied
Nele Festjens
Nico Callewaert
Xavier Saelens
Bart Dermaut
Sven Eyckerman
Francis Impens
A1
Journal Article
in
NATURE COMMUNICATIONS
2021
Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions
Glenn Vergauwen
Joeri Tulkens
Cláudio Pinheiro
Francisco Avila Cobos
Sandor Dedeyne
Marie-Angélique De Scheerder
Linos Vandekerckhove
Francis Impens
Geert Braems
Kris Gevaert
Pieter Mestdagh
Jo Vandesompele
Hannelore Denys
Olivier De Wever
An Hendrix
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2021
The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers
Delphi Van Haver
Francis Impens
A1
Journal Article
in
SCIENTIFIC REPORTS
2021
2020
Active nuclear import of the deacetylase Sirtuin-2 is controlled by its C-terminus and importins
Francis Impens
A1
Journal Article
in
SCIENTIFIC REPORTS
2020
An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates
Francis Impens
A1
Journal Article
in
CANCER CELL
2020
An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates (vol 37, pg 21.e1, 2020)
Francis Impens
Correction
2020
Chemical genetics approach identifies abnormal inflorescence meristem 1 as a putative target of a novel sulfonamide that protects catalase2-deficient Arabidopsis against photorespiratory stress
Tom van der Meer
Arno Verlee
Patrick Willems
Francis Impens
Kris Gevaert
Christian Stevens
Frank Van Breusegem
Pavel Kerchev
A1
Journal Article
in
CELLS
2020
Environmental conditions steer phenotypic switching in acute hepatopancreatic necrosis disease-causing Vibrio parahaemolyticus, affecting PirAVP/PirBVP toxins production
Vikash Kumar
Suvra Roy
Sri Kartik Baruah
Delphi Van Haver
Francis Impens
Peter Bossier
A1
Journal Article
in
ENVIRONMENTAL MICROBIOLOGY
2020
Establishment of proximity-dependent biotinylation approaches in different plant model systems
Deepanksha Arora
Petra Van Damme
Klaas Yperman
Dominique Eeckhout
Lam Dai Vu
Jie Wang
Francis Impens
Jelle Van Leene
Alain Goossens
Geert De Jaeger
Daniël Van Damme
A1
Journal Article
in
PLANT CELL
2020
Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1
Jasmine Barra
Francis Impens
Kris Gevaert
A1
Journal Article
in
SCIENCE ADVANCES
2020
Listeria monocytogenes impairs SUMOylation for efficient infection (vol 464, pg 1192, 2010)
Francis Impens
Kris Gevaert
Joël Vandekerckhove
Correction
2020
Mutations in the ubiquitin ligase adaptor LZTR1 drive human disease by dysregulating RAS ubiquitination and signaling.
Jan Tavernier
Kris Gevaert
Francis Impens
C3
Conference
2020
Protein modification with ISG15 blocks coxsackievirus pathology by antiviral and metabolic reprogramming
Fabien Henri Thery
Francis Impens
A1
Journal Article
in
SCIENCE ADVANCES
2020
Removing the hidden data dependency of DIA with predicted spectral libraries
Bart Van Puyvelde
Sander Willems
Ralf Gabriels
Simon Daled
Laura De Clerck
Sofie Vande Casteele
An Staes
Francis Impens
Dieter Deforce
Lennart Martens
Sven Degroeve
Maarten Dhaenens
A1
Journal Article
in
PROTEOMICS
2020
Simple peptide quantification approach for MS-based proteomics quality control
Teresa Maia
An Staes
Kim Plasman
Jarne Pauwels
Katie Boucher
Andrea Argentini
Lennart Martens
Tony Montoye
Kris Gevaert
Francis Impens
A1
Journal Article
in
ACS OMEGA
2020
Stress-induced lncRNA LASTR fosters cancer cell fitness by regulating the activity of the U4/U6 recycling factor SART3
Delphi Van Haver
Francis Impens
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2020
The Noonan syndrome gene Lztr1 controls cardiovascular function by regulating vesicular trafficking
Francis Impens
A1
Journal Article
in
CIRCULATION RESEARCH
2020
Three decades of listeriology through the prism of technological advances
Francis Impens
A1
Journal Article
in
CELLULAR MICROBIOLOGY
2020
2019
An update on the moFF algorithm for label-free quantitative proteomics
Andrea Argentini
An Staes
Francis Impens
Lennart Martens
A1
Journal Article
in
JOURNAL OF PROTEOME RESEARCH
2019
Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase
Jelle Van Leene
Chao Han
Astrid Gadeyne
Dominique Eeckhout
Caroline Matthijs
Bernard Cannoot
Nancy De Winne
Geert Persiau
Eveline Van De Slijke
Brigitte Van De Cotte
Elisabeth Stes
Michiel Van Bel
Veronique Storme
Francis Impens
Kris Gevaert
Klaas Vandepoele
Ive De Smet
Geert De Jaeger
A1
Journal Article
in
NATURE PLANTS
2019
High-throughput proteome analysis using 50 cm long micro pillar arraycolumns (µPAC)
Francis Impens
Kris Gevaert
C3
Conference
2019
PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome
Teresa Maia
Francis Impens
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2019
Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection
Jolien Van Cleemput
Katrien Poelaert
Kathlyn Laval
Francis Impens
Wim Van Den Broeck
Kris Gevaert
Hans Nauwynck
A1
Journal Article
in
SCIENTIFIC REPORTS
2019
The generation and use of recombinant extracellular vesicles as biological reference material
Edward Geeurickx
Joeri Tulkens
Bert Dhondt
Jan Van Deun
Lien Lippens
Glenn Vergauwen
Delphine De Sutter
Kris Gevaert
Francis Impens
Pieter-Jan Van Bockstal
Thomas De Beer
Geert Braems
Nico Callewaert
Pieter Mestdagh
Jo Vandesompele
Hannelore Denys
Sven Eyckerman
Olivier De Wever
An Hendrix
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
The in vivo ISGylome links ISG15 to metabolic pathways and autophagy upon Listeria monocytogenes infection
Fabien Henri Thery
Francis Impens
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
Ubiquitination of Listeria virulence factor InlC contributes to the host response to infection
Francis Impens
A1
Journal Article
in
MBIO
2019
2018
Comprehensive mapping of the antigenic peptide repertoire during bacterial infection
Rupert Mayer
Teresa Maia
Katie Boucher
Bart Vandekerckhove
Francis Impens
C3
Conference
2018
GSyellow, a multifaceted tag for functional protein analysis in monocot and dicot plants
Nienke Besbrugge
Jelle Van Leene
Dominique Eeckhout
Bernard Cannoot
Shubhada Rajabhau Kulkarni
Nancy De Winne
Geert Persiau
Eveline Van De Slijke
Michiel Bontinck
Stijn Aesaert
Francis Impens
Kris Gevaert
Daniël Van Damme
Maria Van Lijsebettens
Dirk Inzé
Klaas Vandepoele
Hilde Nelissen
Geert De Jaeger
A1
Journal Article
in
PLANT PHYSIOLOGY
2018
Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice
Marlies Ballegeer
Kelly Van Looveren
Steven Timmermans
Melanie Eggermont
Sofie Vandevyver
Fabien Henri Thery
Karen Dendoncker
Jolien Souffriau
Jolien Vandewalle
Lise Van Wyngene
Riet De Rycke
Nozomi Takahashi
Peter Vandenabeele
Francis Impens
Rudi Beyaert
Karolien De Bosscher
Roosmarijn Vandenbroucke
Claude Libert
A1
Journal Article
in
JOURNAL OF CLINICAL INVESTIGATION
2018
Impairment of angiogenesis by fatty acid synthase inhibition involves mTOR malonylation
Evy Timmerman
An Staes
Kris Gevaert
Francis Impens
A1
Journal Article
in
CELL METABOLISM
2018
Infection reveals a modification of SIRT2 critical for chromatin association
Francis Impens
A1
Journal Article
in
CELL REPORTS
2018
Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination
Jan Tavernier
Kris Gevaert
Francis Impens
Sven Eyckerman
A1
Journal Article
in
SCIENCE
2018
N-terminal acetylation levels are maintained during acetyl-CoA deficiency in Saccharomyces cerevisiae
Francis Impens
Delphi Van Haver
Veronique Jonckheere
Kris Gevaert
Petra Van Damme
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2018
NAA80 is actin’s N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility
Evy Timmerman
Francis Impens
Kris Gevaert
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2018
Proteomics reveals scope of mycolactone-mediated Sec61 blockade and distinctive stress signature
Delphi Van Haver
Francis Impens
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2018
Quantitative proteomics and systems analysis of cultured H9C2 cardiomyoblasts during differentiation over time supports a ‘function follows form’ model of differentiation
Delphi Van Haver
Kris Gevaert
Francis Impens
A1
Journal Article
in
MOLECULAR OMICS
2018
Rapid remodeling of the host epithelial cell proteome by the listeriolysin O pore-forming toxin
Francis Impens
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2018
Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research
Edward Geeurickx
Jan Van Deun
Lien Lippens
Joeri Tulkens
Bert Dhondt
Glenn Vergauwen
Kris Gevaert
Francis Impens
Pieter-Jan Van Bockstal
Thomas De Beer
Sven Eyckerman
Pieter Mestdagh
Jo Vandesompele
Geert Braems
Hannelore Denys
Olivier De Wever
An Hendrix
C3
Conference
2018
Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research
Edward Geeurickx
Jan Van Deun
Lien Lippens
Joeri Tulkens
Bert Dhondt
Glenn Vergauwen
Kris Gevaert
Francis Impens
Pieter-Jan Van Bockstal
Thomas De Beer
Sven Eyckerman
Pieter Mestdagh
Jo Vandesompele
Geert Braems
Hannelore Denys
Marc Bracke
Olivier De Wever
An Hendrix
C3
Conference
2018
The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages
Viacheslav Mylka
Julie Deckers
Dariusz Ratman
Lode De Cauwer
Jonathan Thommis
Riet De Rycke
Francis Impens
Claude Libert
Jan Tavernier
Kris Gevaert
Karolien De Bosscher
A1
Journal Article
in
AUTOPHAGY
2018
2017
Legionella pneumophila modulates mitochondrial dynamics to trigger metabolic repurposing of infected macrophages
Francis Impens
A1
Journal Article
in
CELL HOST & MICROBE
2017
N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes
Francis Impens
A1
Journal Article
in
NATURE MICROBIOLOGY
2017
Phase separation of C9orf72 dipeptide repeats perturbs stress granule dynamics
Evy Timmerman
Francis Impens
A1
Journal Article
in
MOLECULAR CELL
2017
Protease substrate profiling by N-terminal COFRADIC
An Staes
Petra Van Damme
Evy Timmerman
Bart Ruttens
Elisabeth Stes
Kris Gevaert
Francis Impens
Bookchapter
in
Protein terminal profiling : methods and protocols
2017
Quality control in mass spectrometry-based proteomics
Francis Impens
An Staes
Evy Timmerman
Lennart Martens
A1
Journal Article
in
MASS SPECTROMETRY REVIEWS
2017
Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export
Francis Impens
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2017
The Legionella pneumophila genome evolved to accommodate multiple regulatory mechanisms controlled by the CsrA-system
Francis Impens
A1
Journal Article
in
PLOS GENETICS
2017
2016
Intelligent mixing of proteomes for elimination of false positives in affinity purification-mass spectrometry
Sven Eyckerman
Francis Impens
Emmy Van Quickelberghe
Noortje Samyn
Giel Vandemoortele
Delphine De Sutter
Jan Tavernier
Kris Gevaert
A1
Journal Article
in
JOURNAL OF PROTEOME RESEARCH
2016
Mycolactone subverts immunity by selectively blocking the Sec61 translocon
Francis Impens
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2016
2015
Fast profiling of protease specificity reveals similar substrate specificities for cathepsins K, L and S
Emmy Van Quickelberghe
Francis Impens
Kris Gevaert
A1
Journal Article
in
PROTEOMICS
2015
ISG15 counteracts Listeria monocytogenes infection
Francis Impens
A1
Journal Article
in
ELIFE
2015
2014
Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli
Francis Impens
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2014
2013
A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis
Katrien Van Impe
Jonas Bethuyne
Steven Cool
Francis Impens
Olivier De Wever
Berlinda Vanloo
Marleen Van Troys
Kathleen Lambein
Ciska Boucherie
Evelien Martens
Olivier Zwaenepoel
Joël Vandekerckhove
Kris Gevaert
Niek Sanders
Jan Gettemans
A1
Journal Article
in
BREAST CANCER RESEARCH
2013
A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection
Francis Impens
A1
Journal Article
in
SCIENCE
2013
Mapping proteolytic processing in the secretome of gastric cancer-associated myofibroblasts reveals activation of MMP-1, MMP-2, and MMP-3
Bart Ghesquière
Francis Impens
Kris Gevaert
A1
Journal Article
in
JOURNAL OF PROTEOME RESEARCH
2013
The Online Protein Processing Resource (TOPPR) : a database and analysis platform for protein processing events
Niklaas Colaert
Davy Maddelein
Francis Impens
Petra Van Damme
Kim Plasman
Kenny Helsens
Niels Hulstaert
Joël Vandekerckhove
Kris Gevaert
Lennart Martens
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2013
Vpr content of HIV-1 virions determines infection of resting peripheral blood CD4⁺ lymphocytes
Anouk Van Nuffel
Francis Impens
Ann Baeyens
Stijn Vanhee
Wojciech Witkowski
Elien Vandermarliere
Hanne Vanderstraeten
Evelien Naessens
Kathleen Van Landeghem
Sophie Vermaut
Kathleen Moens
Petra Van Damme
Kris Gevaert
Bruno Verhasselt
C3
Conference
2013
2012
A catalogue of putative HIV-1 protease host cell substrates
Francis Impens
Evy Timmerman
An Staes
Kathleen Moens
Kevin Ariën
Bruno Verhasselt
Joël Vandekerckhove
Kris Gevaert
A1
Journal Article
in
BIOLOGICAL CHEMISTRY
2012
Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike
Magdalena Wejda
Francis Impens
Nozomi Takahashi
Petra Van Damme
Kris Gevaert
Peter Vandenabeele
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2012
The Apaf-1-binding protein Aven is cleaved by Cathepsin D to unleash its anti-apoptotic potential
Francis Impens
Kris Gevaert
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2012
2011
N-Terminal combined fractional diagonal chromatographic (COFRADIC) analysis of the human platelet proteome
Francis Impens
Kenny Helsens
Niklaas Colaert
Lennart Martens
Joël Vandekerckhove
Kris Gevaert
Bookchapter
in
Platelet proteomics : principles, analysis, and applications
2011
Probing the efficiency of proteolytic events by positional proteomics
Kim Plasman
Petra Van Damme
Francis Impens
Kimberly Demeyer
Kenny Helsens
Marc Goethals
Joël Vandekerckhove
Kris Gevaert
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2011
Selecting protein N-terminal peptides by combined fractional diagonal chromatography
An Staes
Francis Impens
Petra Van Damme
Bart Ruttens
Marc Goethals
Hans Demol
Evy Timmerman
Joël Vandekerckhove
Kris Gevaert
A1
Journal Article
in
NATURE PROTOCOLS
2011
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma
Pieter Mestdagh
Francis Impens
Gert Van Peer
Bart Ghesquière
Kris Gevaert
Franki Speleman
Jo Vandesompele
C3
Conference
2011
m-Calpain activation in vitro does not require autolysis or subunit dissociation
Francis Impens
Kris Gevaert
A1
Journal Article
in
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
2011
2010
A quantitative proteomics design for systematic identification of protease cleavage events
Francis Impens
Niklaas Colaert
Kenny Helsens
Bart Ghesquière
Evy Timmerman
Pieter-Jan De Bock
Joël Vandekerckhove
Kris Gevaert
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2010
Listeria monocytogenes impairs SUMOylation for efficient infection
Francis Impens
Kris Gevaert
Joël Vandekerckhove
A1
Journal Article
in
NATURE
2010
MS-driven protease substrate degradomics
Francis Impens
Niklaas Colaert
Kenny Helsens
Kim Plasman
Petra Van Damme
Joël Vandekerckhove
Kris Gevaert
A1
Journal Article
in
PROTEOMICS
2010
Rover: a tool to visualize and validate quantitative proteomics data from different sources
Niklaas Colaert
Kenny Helsens
Francis Impens
Joël Vandekerckhove
Kris Gevaert
A1
Journal Article
in
PROTEOMICS
2010
Studying in vitro and in vivo protease processing in models of cancer cell death and viral infection by N-terminal COFRADIC
Francis Impens
Kris Gevaert
Dissertation
2010
The miR-17-92 MicroRNA Cluster regulates multiple components of the TGF-beta Pathway in neuroblastoma
Pieter Mestdagh
Francis Impens
Gert Van Peer
Bart Ghesquière
Kris Gevaert
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
MOLECULAR CELL
2010
Who gets cut during cell death?
Francis Impens
Joël Vandekerckhove
Kris Gevaert
A1
Journal Article
in
CURRENT OPINION IN CELL BIOLOGY
2010
mir-17-92 is a master regulator of TGFβ-pathway activity in neuroblastoma
Pieter Mestdagh
Francis Impens
Bart Ghesquière
Kris Gevaert
Franki Speleman
Jo Vandesompele
C3
Conference
2010
2009
Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity
Dieter Demon
Petra Van Damme
Tom Vanden Berghe
Annelies Deceuninck
Joost Van Durme
Jelle Verspurten
Kenny Helsens
Francis Impens
Magdalena Wejda
Annemieke Madder
Joël Vandekerckhove
Wim Declercq
Kris Gevaert
Peter Vandenabeele
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2009
2008
Mechanistic insight into taxol-induced cell death
Francis Impens
Petra Van Damme
Hans Demol
Jozef Van Damme
Joël Vandekerckhove
Kris Gevaert
A1
Journal Article
in
ONCOGENE
2008
Protein processing characterized by a gel-free proteomics approach
Petra Van Damme
Francis Impens
Joël Vandekerckhove
Kris Gevaert
Bookchapter
in
Functional proteomics, part III
2008
Stable isotopic labeling in proteomics
Kris Gevaert
Francis Impens
Bart Ghesquière
Petra Van Damme
Anja Lambrechts
Joël Vandekerckhove
A1
Journal Article
in
PROTEOMICS
2008
2007
A la carte proteomics with an emphasis on gel-free techniques
Kris Gevaert
Petra Van Damme
Bart Ghesquière
Francis Impens
Lennart Martens
Kenny Helsens
Joël Vandekerckhove
A1
Journal Article
in
PROTEOMICS
2007
Applications of diagonal chromatography for proteome-wide characterization of protein modifications and activity-based analyses
Kris Gevaert
Francis Impens
Petra Van Damme
Bart Ghesquière
Joël Vandekerckhove
A1
Journal Article
in
FEBS JOURNAL
2007