Research Explorer

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Researcher

Francis Impens

Publications & Research Data

Awards & Distinctions

167 Results

2026

Belgian recommendations for tissue diagnosis of amyloidosis

Amélie DendoovenAnnelore VandendriesschePriyanka Joseph KoshyFrank TimmermansMarijn SpeeckaertNicolas KintLucas Van AelstMarie-Christiane VekemansNathalie MeulemanAnne-Catherine Pouleur et al.

A1 Journal Article in ACTA CLINICA BELGICA

Bioengineered baculovirus-derived extracellular vesicles loaded with of γ-carboxylated Gla-rich protein : dual modulation of inflammation and vascular calcification

Carla ViegasSimon PichardJoana CarreiraAdélia OvaNathalie Troffer-CharlierTeresa MaiaEvelina EdelweissAnjos L MacedoAntónio MatosTiago Q Faria et al.

A1 Journal Article in BIOMATERIALS ADVANCES

Increased plasma fibronectin mirrors intimal phenotypic switching of vascular smooth muscle cells in moyamoya arteriopathy

Caroline AsselmanJozefien MeersschautPatrick WillemsJulien MortierFrank VernaillenElisabeth DhondtAnne SiebenSasha LibbrechtMaria Fernandez FernandezKris Gevaert et al.

A1 Journal Article in SCIENTIFIC REPORTS

Large-scale proteomics profiling of peripheral blood of DM1 patients identifies biomarkers for disease severity and functional capacity

Daniël van AsTine ClaeysRenee SalzDelphi Van HaverSara DufourAmber van DeelenJolein GloerichRalf GabrielsPieter Jan VoldersVera Dobelmann et al.

A1 Journal Article in JOURNAL OF NEUROMUSCULAR DISEASES

Multi-omics profiling reveals molecular pathways involved in RNF216-mediated neurodegeneration

Axelle VersavelLauren VersluysLotte KeymeulenMarthe De BoeckAnne SiebenPatrick SantensJo Van DorpeFrancis ImpensSven EyckermanBart Dermaut et al.

Multi-omics profiling reveals molecular pathways involved in RNF216-mediated neurodegeneration

Axelle VersavelLauren VersluysLotte KeymeulenMarthe De BoeckAnne SiebenPatrick SantensJo Van DorpeFrancis ImpensSven EyckermanBart Dermaut et al.

Proteomics and tracer metabolomics link GAPDH ISGylation to glycolytic control

Denzel EggermontLissa EggermontNagihan AslantaşFabien Henri TheryKatie BoucherAntje BelingBart GhesquièreFrancis Impens

A1 Journal Article in GENOME BIOLOGY

Serum H-ferritin-to-ferritin ratio as a biomarker of hemophagocytic lymphohistiocytosis in critically ill patients with hyperferritinemia

France DebaugniesFrank GoetzingerFleur WolffFrancis ImpensSara DufourDelphi Van HaverPhilippe GottigniesRaphaël La SchiazzaBhavna MahadebNathalie Meuleman et al.

A1 Journal Article in AMERICAN JOURNAL OF HEMATOLOGY

2025

A multiyear longitudinal harmonization study of quality controls in mass spectrometry proteomics core facilities

Cristina ChivaRoger OlivellaAn StaesTeresa MaiaChristian PanseKarel StejskalThibaut DouchéBérangère LombardAndrea SchuhmannDamarys Loew et al.

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Blood proteome profiling for biomarker discovery in broilers with necrotic enteritis

Svitlana TretiakTeresa MaiaDelphi Van HaverAn StaesSimon DevosTom RijsselaereEvy GoossensFilip Van ImmerseelFrancis ImpensGunther Antonissen

A1 Journal Article in SCIENTIFIC REPORTS

Challenges and opportunities in mRNA vaccine development against bacteria

Ilke AernoutRein VerbekeFabien Henri TheryPatrick WillemsUri EliaStefaan De SmedtRino RappuoliDan PeerFrancis ImpensIne Lentacker

A1 Journal Article in NATURE MICROBIOLOGY

Characterization of RNF213 in antimicrobial defense and Moyamoya disease progression

Caroline AsselmanFrancis ImpensBart Dermaut

Collisional cross-section prediction for multiconformational peptide ions with IM2Deep

Robbe DevreeseAlireza NameniArthur DeclercqEmmy TerrynRalf GabrielsFrancis ImpensKris GevaertLennart MartensRobbin Bouwmeester

A1 Journal Article in ANALYTICAL CHEMISTRY

Comprehensive analysis of blood proteome response to necrotic enteritis in broiler chicken

Svitlana TretiakTeresa MaiaTom RijsselaereFilip Van ImmerseelRichard DucatelleFrancis ImpensGunther Antonissen

A1 Journal Article in VETERINARY RESEARCH

Current state of mRNA vaccine development against Mycobacterium tuberculosis

Ilke AernoutRein VerbekeStefaan De SmedtFrancis ImpensIne Lentacker

Bookchapter in Trends in mRNA vaccine research

Data-independent immunopeptidomics discovery of low-abundant bacterial epitopes

Patrick WillemsAn StaesLaia Miret CasalsVadim DemichevSimon DevosFrancis Impens

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Epitope Odyssey : data-driven tools to extend the known immunopeptide universe

Arthur DeclercqLennart MartensFrancis Impens

Getting close to RNF216 : proximity labeling reveals links between nuclear condensates, splicing and neurodegeneration

Lauren VersluysAxelle VersavelLotte KeymeulenAnne SiebenNika SchuermansElisabeth Mondragon RezolaPatrick SantensJo Van DorpeFrancis ImpensSven Eyckerman et al.

Identification of DksA as a novel pro-inflammatory mediator of <i>Pseudomonas aeruginosa</i> under conditions mimicking chronic cystic fibrosis lung infection

Merel WautersLaura BolléSara Van den BosscheLucia GrassiDelphi Van HaverSara DufourSimon DevosFrancis ImpensEva Van BraeckelAnna K.H. Hirsch et al.

Immunopeptidomics identified antigens for mRNA-lipid nanoparticle vaccines with alpha-galactosylceramide in multiple myeloma therapy

Arne van der VrekenFabien Henri TheryChenggong TuKevin MwangiSofie MeulewaeterLien De BeckEdith JanssensKim De VeirmanKarin VanderkerkenElke De Bruyne et al.

A1 Journal Article in JOURNAL FOR IMMUNOTHERAPY OF CANCER

Maximizing immunopeptidomics-based bacterial epitope discovery by multiple search engines and rescoring

Patrick WillemsFabien Henri TheryLaura Van MoortelMargaux De MeyerAn StaesAdillah GulLyudmila KovalchukeArthur DeclercqRobbe DevreeseRobbin Bouwmeester et al.

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Proteomic profiling of dysbiosis-challenged broilers reveals potential blood biomarkers for intestinal health

Svitlana TretiakTeresa MaiaRichard DucatelleMarc CherletTom RijsselaereFilip Van ImmerseelFrancis ImpensGunther Antonissen

A1 Journal Article in VETERINARY RESEARCH

Proteomics- and metabolomics-based analysis of the regulation of germination in Norway maple and sycamore embryonic axes

Ewa Marzena KalembaSara DufourKris GevaertFrancis ImpensPatrice Meimoun

A1 Journal Article in TREE PHYSIOLOGY

Proteomics-based analysis of laser-capture micro-dissected, formalin-fixed paraffin-embedded tissue samples

Teresa MaiaDelphi Van HaverSara DufourMalaïka Van der LindenAmélie DendoovenFrancis ImpensSimon Devos

Bookchapter in Tissue proteomics : methods and protocols

Structural and proteomic analysis of the mouse cathepsin B-DARPin 4m3 complex reveals species-specific binding determinants

Miki ZarićLivija TušarLovro KramerOlga VasiljevaMatej NovakFrancis ImpensAleksandra UsenikKris GevaertDušan TurkBoris Turk

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Target acquired : lock-on bacterial immunopeptides

Patrick WillemsLyudmila KovalchukeFrancis Impens

Editorial material

The surface proteome of bovine unsexed and sexed spermatozoa

Patrícia Pinto-PinhoJoana QuelhasFrancis ImpensSara DufourDelphi Van HaverGraça LopesAntónio RochaRosário Pinto-LeiteMargarida FardilhaBruno Colaço

A1 Journal Article in ANIMALS

The surface proteome of rabbit spermatozoa

Patrícia Pinto-PinhoFrancis ImpensSara DufourDelphi Van HaverRosário Pinto-LeiteJohn HowlMargarida FardilhaBruno Colaço

A1 Journal Article in ANIMAL REPRODUCTION SCIENCE

Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of Pseudomonas aeruginosa in an organotypic 3D lung epithelial cell model

Merel WautersSara Van den BosscheLucia GrassiMariana Fernandes GonçalvesDelphi Van HaverSara DufourSimon DevosLeander MeurisFrancis ImpensXavier Saelens et al.

A1 Journal Article in VIRULENCE

2024

Alpha-galactosylceramide improves the potency of mRNA LNP vaccines against cancer and intracellular bacteria

Sofie MeulewaeterIlke AernoutJoke DeprezYanou EngelenMargo De VelderLorenzo FranceschiniKarine BreckpotSerge Van CalenberghCaroline AsselmanKatie Boucher et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Benefit of in silico predicted spectral libraries in data-independent acquisition data analysis workflows

An StaesTeresa MaiaSara DufourRobbin BouwmeesterRalf GabrielsLennart MartensKris GevaertFrancis ImpensSimon Devos

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

From blood proteome to gut health : decoding blood-based biomarkers through proteomics

Svitlana TretiakGunther AntonissenFilip Van ImmerseelFrancis ImpensTom Rijsselaere

High-throughput nanoflow proteomics using a dual-column electrospray source

An StaesKatie BoucherSara DufourTeresa MaiaEvy TimmermanDelphi Van HaverJarne PauwelsHans DemolJonathan VandenbusscheKris Gevaert et al.

A1 Journal Article in ANALYTICAL CHEMISTRY

Host dependency factors of the influenza virus : a dual-omics approach

Annabel MaesXavier SaelensFrancis Impens

Immunopeptidomics mapping of Listeria monocytogenes T cell epitopes in mice

Adillah GulLecia L. PewePatrick WillemsRupert MayerFabien Henri TheryCaroline AsselmanIlke AernoutRein VerbekeDenzel EggermontLaura Van Moortel et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

In vivo proteolytic profiling of the type I and type II metacaspases in Chlamydomonas reinhardtii exposed to salt stress

Georgia Antonia VergouAmit K BajhaiyaLuisa CorredorSaul Lema AsquiEvy TimmermanFrancis ImpensChristiane Funk

A1 Journal Article in PHYSIOLOGIA PLANTARUM

ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection

Clara BredowFabien Henri TheryEva Katrin WirthSarah OchsMeike KespohlGunnar KleinauNicolas KelmNiclas GimberJan SchmoranzerMartin Voss et al.

A1 Journal Article in CARDIOVASCULAR RESEARCH

Loss of phospholipase PLAAT3 causes a mixed lipodystrophic and neurological syndrome due to impaired PPARγ signaling

Nika SchuermansSalima El ChehadehDimitri HemelsoetJeremie GautheronMarie-Christine VantyghemSonia NouiouaMeriem TazirCorinne VigourouxMartine AuclairElke Bogaert et al.

Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Joline IngelsLaurenz De CockDieter StevensRupert MayerFabien Henri TheryGuillem Sanchez SanchezDavid VermijlenKarin WeeningSaskia De SmetNele Lootens et al.

A1 Journal Article in CELL REPORTS MEDICINE

Paneth cell TNF signaling induces gut bacterial translocation and sepsis

Charlotte WallaeysNatalia Garcia GonzalezSteven TimmermansJolien VandewalleTineke VanderhaeghenSomara De BeulHester DufoorMelanie EggermontElise MoensVictor Bosteels et al.

A1 Journal Article in CELL HOST & MICROBE

Proteomic insights into the gut health of broilers : blood-based biomarkers to bridge inflammatory models

Svitlana TretiakTeresa MaiaFrancis ImpensTom RijsselaereFilip Van ImmerseelGunther Antonissen

Revealing the transitory and local effect of zebularine on development and on proteome dynamics of Salix purpurea

Andrea PaganoCarolina GomesEvy TimmermanPaweł SulimaJerzy Andrzej PrzyborowskiDariusz KruszkaFrancis ImpensJorge Almiro Pinto Paiva

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

Shifting mass spectrometry-based proteomics to the fast lane : an interplay between high throughput LC and data independent acquisition without compromising depth, precision or accuracy

An StaesKris GevaertFrancis ImpensSimon Devos

SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains

Arne JanssensVan Son NguyenAdam J CecilSander E Van der VerrenEvy TimmermanMichaël DegheltAlexander J PakJean-François ColletFrancis ImpensHan Remaut

A1 Journal Article in NATURE

Systematic review and meta-analysis of genome-wide pooled CRISPR screens to identify host factors involved in influenza A virus infection

Annabel MaesAlexander BotzkiJanick MathysFrancis ImpensXavier Saelens

A1 Journal Article in JOURNAL OF VIROLOGY

The association of protein-bound methionine sulfoxide with proteomic basis for aging in beech seeds

Ewa Marzena KalembaKris GevaertFrancis ImpensSara DufourAnna Czerwoniec

A1 Journal Article in BMC PLANT BIOLOGY

The promise of omics approaches for pediatric drug development

Sigrid VerhelstTess GoessensRoger Peró GascónMarthe De BoevreFrancis ImpensDieter DeforceMaarten Dhaenens

Bookchapter in Essentials of translational pediatric drug development : from past needs to future oportunities

2023

Cells responding to closely related cholesterol-dependent cytolysins release extracellular vesicles with a common proteomic content including membrane repair proteins

S AlvesJM PereiraRupert MayerADA GonçalvesFrancis ImpensD CabanesS Sousa

A1 Journal Article in TOXINS

Complementary peptides represent a credible alternative to agrochemicals by activating translation of targeted proteins

M OrmanceyB GuillotinR MerretL CambordeC DuboéB FabreC PouzetFrancis ImpensDelphi Van HaverMC Carpentier et al.

A1 Journal Article in NATURE COMMUNICATIONS

CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity

W GuoH WangA Kumar TharkeshwarJ CouthouisE BraemsP MasroriE Van SchoorY FanK AhujaM Moisse et al.

A1 Journal Article in ALZHEIMERS & DEMENTIA

CysQuant : simultaneous quantification of cysteine oxidation and protein abundance using data dependent or independent acquisition mass spectrometry

Jingjing HuangAn StaesFrancis ImpensVadim DemichevFrank Van BreusegemKris GevaertPatrick Willems

A1 Journal Article in REDOX BIOLOGY

Large-scale proteomics profiling of peripheral blood of DM1 patients identifies biomarkers for disease severity and physical activity

P. 't HoenD. van AsTine ClaeysR. SalzRalf GabrielsFrancis ImpensPieter-Jan VoldersLennart MartensB. van Engelen

Loss of phospholipase PLAAT3 causes a mixed lipodystrophic and neurological syndrome due to impaired PPARγ signaling

Nika SchuermansSalima El ChehadehDimitri HemelsoetJérémie GautheronMarie-Christine VantyghemSonia NouiouaMeriem TazirCorinne VigourouxMartine AuclairElke Bogaert et al.

A1 Journal Article in NATURE GENETICS

MIDRIXNEO-LUNG : safety and immunogenicity of a neoantigen-presenting autologous dendritic cell therapy in resected NSCLC patients

Joline IngelsLaurenz De CockDieter StevensKarin WeeningVeerle SurmontJo Van DorpeFrancis ImpensBjörn MentenKarim VermaelenBart Vandekerckhove

Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins

Livija TušarJure LobodaFrancis ImpensPiotr SosnowskiEmmy Van QuickelbergheRobert VidmarHans DemolKoen SedeynXavier SaelensMatej Vizovišek et al.

A1 Journal Article in COMMUNICATIONS BIOLOGY

Proteomics-based analysis and diagnosis of formalin-fixed paraffin-embedded amyloidosis samples

Delphi Van HaverAmélie DendoovenFrancis Impens

Bookchapter in Mass Spectrometry-Based Proteomics

RHOJ controls EMT-associated resistance to chemotherapy

M DebaugniesS Rodríguez-AcebesJ BlondeauMA ParentM ZoccoY SongV de MaertelaerV MoersM LatilC Dubois et al.

A1 Journal Article in NATURE

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

Lore BillietLaurenz De CockGuillem Sanchez SanchezRupert MayerGlenn GoetgelukStijn De MunterMelissa PilleJoline IngelsHanne JansenKarin Weening et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space

E AdriaenssensB AsselberghP Rivera-MejíasS BervoetsL VendredyV De WinterK SpaasRiet De RyckeGert Van IsterdaelFrancis Impens et al.

A1 Journal Article in NATURE CELL BIOLOGY

Spatial mechano-signaling regulation of GTPases through non-degradative ubiquitination

Raj N SewduthPaolo CaraiTonci IvanisevicMingzhen ZhangHyunbum JangBenoit LechatDelphi Van HaverFrancis ImpensRuth NussinovElizabeth Jones et al.

A1 Journal Article in ADVANCED SCIENCE

Systematic compositional analysis of exosomal extracellular vesicles produced by cells undergoing apoptosis, necroptosis and ferroptosis

Benjamin CappeMike VadiEliza SackLudivine WacheulBruno VerstraetenSara DufourJulien FranckWei XieFrancis ImpensAn Hendrix et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

The deubiquitinase OTUB1 governs lung cancer cell fitness by modulating proteostasis of OXPHOS proteins

A SheryazdanovaND AmoedoSara DufourFrancis ImpensR RossignolA Sablina

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The extracellular matrix dictates regional competence for tumour initiation

Nordin BansaccalPauline VieugueRahul SarateYura SongEsmeralda MinguijonYekaterina A MiroshnikovaDagmar ZeuschnerAmandine CollinJustine AllardDan Engelman et al.

A1 Journal Article in NATURE

The nutritional composition and cell size of microbial biomass for food applications are defined by the growth conditions

Myrsini SakarikaFrederiek-Maarten KerckhofLotte Van PeteghemAlexandra Pinto Martins PereiraTim Van Den BosscheRobbin BouwmeesterRalf GabrielsDelphi Van HaverBarbara UlčarLennart Martens et al.

A1 Journal Article in MICROBIAL CELL FACTORIES

2022

A cytosolic disulfide bridge-supported dimerization is crucial for stability and cellular distribution of Coxsackievirus B3 protein 3A

M VossG KleinauN GimberK JanekC BredowFabien Henri TheryFrancis ImpensJ SchmoranzerP ScheererPM Kloetzel et al.

A1 Journal Article in FEBS JOURNAL

A strong cation exchange chromatography protocol for examining N-terminal proteoforms

Esperanza FernándezAnnelies BogaertEvy TimmermanAn StaesFrancis ImpensKris Gevaert

Bookchapter in Yeast functional genomics : methods and protocols

An unexpected encounter : respiratory syncytial virus nonstructural protein 1 interacts with mediator subunit MED25

Tessa Van RoyenKoen SedeynGeorgios MoschonasWendy ToussaintM VuylstekeDelphi Van HaverFrancis ImpensSven EyckermanIrma LemmensJan Tavernier et al.

A1 Journal Article in JOURNAL OF VIROLOGY

Characterization of RBPome in oxidative stress conditions

Zhicheng ZhangEvy TimmermanFrancis ImpensFrank Van Breusegem

Bookchapter in Reactive oxygen species in plants : methods and protocols

Characterization of the Arabidopsis RBPome in oxidative stress conditions

Zhicheng ZhangEvy TimmermanFrancis ImpensFrank Van Breusegem

Functional characterization of RNF213 as newly discovered ISG15 sensor during infection

Lia MartinaFrancis ImpensSven Eyckerman

How tech-savvy employees make the difference in core facilities : recognizing core facility expertise with dedicated career tracks

Saskia LippensDominique AudenaertAlexander BotzkiStefaan DerveauxBart GhesquièreGeert GoeminneReza HassanzadehJurgen HaustraeteFrancis ImpensJochen Lamote et al.

Editorial material

Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes

Rupert MayerRein VerbekeCaroline AsselmanIlke AernoutAdillah GulDenzel EggermontKatie BoucherFabien Henri TheryTeresa MaiaHans Demol et al.

A1 Journal Article in NATURE COMMUNICATIONS

Moyamoya disease emerging as an immune-related angiopathy

Caroline AsselmanDimitri HemelsoetDenzel EggermontBart DermautFrancis Impens

A1 Journal Article in TRENDS IN MOLECULAR MEDICINE

Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division

S PetracchiniD HamaouiA DoyeA AsnaciosF FageE VitielloM BallandS JanelF LafontM Gupta et al.

A1 Journal Article in NATURE COMMUNICATIONS

Proteome-wide cellular thermal shift assay reveals unexpected cross-talk between brassinosteroid and auxin signaling

Qing LuYonghong ZhangJoakim HellnerCaterina GianniniXiangyu XuJarne PauwelsQian MaWim DejongheHuibin HanBrigitte Van De Cotte et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomics-based characterization of ISG15 signaling in host defense mechanisms against microbial infection

Fabien Henri TheryFrancis ImpensSven Eyckerman

Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials

Joline IngelsLaurenz De CockRupert MayerPam DevrekerKarin WeeningKelly HeynsNele LootensSaskia De SmetMarieke BrusseelStijn De Munter et al.

A1 Journal Article in CYTOTHERAPY

The final maturation state of β-actin involves N-terminal acetylation by NAA80, not N-terminal arginylation by ATE1

Adrian DrazicEvy TimmermanUlrike KajanMichaël MarieSylvia VarlandFrancis ImpensKris GevaertThomas Arnesen

A1 Journal Article in JOURNAL OF MOLECULAR BIOLOGY

2021

ATP13A3 is a major component of the enigmatic mammalian polyamine transport system

Norin Nabil HamoudaChris Van den HauteRoeland VanhoutteRagna SannerudMujahid AzfarRupert MayerAlvaro Cortes CalabuigJohannes V. SwinnenPatrizia AgostinisVeerle Baekelandt et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis

Ievgenia PastushenkoFederico MauriYura SongFlorian de CockBob MeeusenBenjamin SwedlundFrancis ImpensDelphi Van HaverMatthieu OpitzManuel Thery et al.

A1 Journal Article in NATURE

Identification of the MuRF1 skeletal muscle ubiquitylome through quantitative proteomics

LM BaehrDC HughesSA LynchDelphi Van HaverTeresa MaiaAG MarshallL RadoshevichFrancis ImpensDS WaddellSC Bodine

A2 Journal Article in FUNCTION (OXFORD)

Immunopeptidomics for next-generation bacterial vaccine development

Rupert MayerFrancis Impens

A1 Journal Article in TRENDS IN MICROBIOLOGY

Loss-of-function mutations in TRAF7 and KLF4 cooperatively activate RAS-like GTPase signaling and promote meningioma development

P NajmP ZhaoM SteklovRN SewduthMF BaiettiS PandolfiN CriemB LechatTeresa MaiaDelphi Van Haver et al.

A1 Journal Article in CANCER RESEARCH

Mechanisms of congenital heart disease caused by NAA15 haploinsufficiency

Tarsha L. WardWarren TaiSarah U. MortonFrancis ImpensPetra Van DammeDelphi Van HaverEvy TimmermanGabriela VenturiniKehan ZhangMin Young Jang et al.

A1 Journal Article in CIRCULATION RESEARCH

Proteome profiling of RNF213 depleted cells reveals nitric oxide regulator DDAH1 antilisterial activity

Lia MartinaCaroline AsselmanFabien Henri TheryKatie BoucherLouis DelhayeTeresa MaiaBart DermautSven EyckermanFrancis Impens

A1 Journal Article in FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

Proteomics mapping of the ISGylation landscape in innate immunity

Fabien Henri TheryDenzel EggermontFrancis Impens

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Quality standards in proteomics research facilities : common standards and quality procedures are essential for proteomics facilities and their users

C ChivaTeresa MaiaC PanseK StejskalT DouchéM MatondoD LoewD HelmM RettelK Mechtler et al.

Editorial material

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity

Fabien Henri TheryLia MartinaCaroline AsselmanHeidi RepoY ZhangKoen SedeynGeorgios MoschonasC BredowQW TeoJ Zhang et al.

A1 Journal Article in NATURE COMMUNICATIONS

Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions

Glenn VergauwenJoeri TulkensCláudio PinheiroFrancisco Avila CobosSandor DedeyneMarie-Angélique De ScheerderLinos VandekerckhoveFrancis ImpensIlkka MiinalainenGeert Braems et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers

Stijn MoensPeihua ZhaoMaria Francesca BaiettiOliviero MarinelliDelphi Van HaverFrancis ImpensGiuseppe FlorisElisabetta MarangoniPatrick NevenDaniela Annibali et al.

A1 Journal Article in SCIENTIFIC REPORTS

2020

Active nuclear import of the deacetylase Sirtuin-2 is controlled by its C-terminus and importins

Eldridge MJGJM PereiraFrancis ImpensMA Hamon

A1 Journal Article in SCIENTIFIC REPORTS

An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates

Jermaine GoveiaKaterina RohlenovaFederico TavernaLucas TrepsLena-Christin ConradiAndreas PircherVincent GeldhofLaura P. M. H. de RooijJoanna KaluckaLiliana Sokol et al.

A1 Journal Article in CANCER CELL

An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates (vol 37, pg 21.e1, 2020)

Jermaine GoveiaKaterina RohlenovaFederico TavernaLucas TrepsLena-Christin ConradiAndreas PircherVincent GeldhofLaura P. M. H. de RooijJoanna KaluckaLiliana Sokol et al.

Chemical genetics approach identifies abnormal inflorescence meristem 1 as a putative target of a novel sulfonamide that protects catalase2-deficient Arabidopsis against photorespiratory stress

Tom van der MeerArno VerleePatrick WillemsFrancis ImpensKris GevaertChrista TesterinkChristian StevensFrank Van BreusegemPavel Kerchev

A1 Journal Article in CELLS

Environmental conditions steer phenotypic switching in acute hepatopancreatic necrosis disease-causing Vibrio parahaemolyticus, affecting PirAVP/PirBVP toxins production

Vikash KumarSuvra RoySri Kartik BaruahDelphi Van HaverFrancis ImpensPeter Bossier

A1 Journal Article in ENVIRONMENTAL MICROBIOLOGY

Establishment of proximity-dependent biotinylation approaches in different plant model systems

Deepanksha AroraNikolaj B. AbelChen LiuPetra Van DammeKlaas YpermanDominique EeckhoutLam Dai VuJie WangAnna TornkvistFrancis Impens et al.

A1 Journal Article in PLANT CELL

Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1

Jasmine BarraGabriel S. GaidoshEzra BlumenthalFelipe BeckedorffMina M. TayariNina KirsteinTobias K. KarakachTorben Heick JensenFrancis ImpensKris Gevaert et al.

A1 Journal Article in SCIENCE ADVANCES

Listeria monocytogenes impairs SUMOylation for efficient infection (vol 464, pg 1192, 2010)

D RibetM HamonE GouinMA NahoriFrancis ImpensH Neyret-KahnKris GevaertJoël VandekerckhoveA DejeanP Cossart

Mutations in the ubiquitin ligase adaptor LZTR1 drive human disease by dysregulating RAS ubiquitination and signaling.

Mikhail SteklovSilvia PandolfiMaria Francesca BaiettiPaolo CaraiMingzhen ZhangHyunbum JangYanyan CaiEric LegiusJan TavernierKris Gevaert et al.

Protein modification with ISG15 blocks coxsackievirus pathology by antiviral and metabolic reprogramming

Meike KespohlClara BredowKarin KlingelMartin VoßAnna PaeschkeMartin ZicklerWolfgang PollerZiya KayaJohannes EcksteinHenry Fechner et al.

A1 Journal Article in SCIENCE ADVANCES

Removing the hidden data dependency of DIA with predicted spectral libraries

Bart Van PuyveldeSander WillemsRalf GabrielsSimon DaledLaura De ClerckSofie Vande CasteeleAn StaesFrancis ImpensDieter DeforceLennart Martens et al.

A1 Journal Article in PROTEOMICS

Simple peptide quantification approach for MS-based proteomics quality control

Teresa MaiaAn StaesKim PlasmanJarne PauwelsKatie BoucherAndrea ArgentiniLennart MartensTony MontoyeKris GevaertFrancis Impens

A1 Journal Article in ACS OMEGA

Stress-induced lncRNA LASTR fosters cancer cell fitness by regulating the activity of the U4/U6 recycling factor SART3

Linde De TroyerPeihua ZhaoTibor PastorMaria Francesca BaiettiJasmine BarraRoberto VendraminRuveyda DokBenoit LechatPaul NajmDelphi Van Haver et al.

A1 Journal Article in NUCLEIC ACIDS RESEARCH

The Noonan syndrome gene Lztr1 controls cardiovascular function by regulating vesicular trafficking

Raj Nayan SewduthSilvia PandolfiMikhail SteklovAidana SheryazdanovaPeihua ZhaoNathan CriemMaria F. BaiettiBenoit LechatRozeen QuarckFrancis Impens et al.

A1 Journal Article in CIRCULATION RESEARCH

Three decades of listeriology through the prism of technological advances

Francis ImpensOlivier Dussurget

A1 Journal Article in CELLULAR MICROBIOLOGY

2019

An update on the moFF algorithm for label-free quantitative proteomics

Andrea ArgentiniAn StaesBjörn Andreas GrüningSubina MehtaCaleb EasterlyTimothy GriffinPratik JagtapFrancis ImpensLennart Martens

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase

Jelle Van LeeneChao HanAstrid GadeyneDominique EeckhoutCaroline MatthijsBernard CannootNancy De WinneGeert PersiauEveline Van De SlijkeBrigitte Van De Cotte et al.

A1 Journal Article in NATURE PLANTS

High-throughput proteome analysis using 50 cm long micro pillar arraycolumns (µPAC)

Jeff Op De BeeckGeert Van RaemdonckPaul JacobsGert DesmetWim De MalscheFrancis ImpensKris Gevaert

PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome

Marco SpinazziEnrico RadaelliKatrien HorreAmaia M. ArranzNatalia V. GounkoPatrizia AgostinisTeresa MaiaFrancis ImpensVanessa Alexandra MoraisGuillermo Lopez-Lluch et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection

Jolien Van CleemputKatrien PoelaertKathlyn LavalFrancis ImpensWim Van Den BroeckKris GevaertHans Nauwynck

A1 Journal Article in SCIENTIFIC REPORTS

The generation and use of recombinant extracellular vesicles as biological reference material

Edward GeeurickxJoeri TulkensBert DhondtJan Van DeunLien LippensGlenn VergauwenElisa HeyrmanDelphine De SutterKris GevaertFrancis Impens et al.

A1 Journal Article in NATURE COMMUNICATIONS

The in vivo ISGylome links ISG15 to metabolic pathways and autophagy upon Listeria monocytogenes infection

Yifeng ZhangFabien Henri TheryNicholas C. WuEmma K. LuhmannOlivier DussurgetMariko FoeckeClara BredowDaniel Jiménez-FernándezKevin LeandroAntje Beling et al.

A1 Journal Article in NATURE COMMUNICATIONS

Ubiquitination of Listeria virulence factor InlC contributes to the host response to infection

E GouinD BalestrinoO RasidMA NahoriV VilliersFrancis ImpensS VolantT VoglY JacobO Dussurget et al.

A1 Journal Article in MBIO

2018

Comprehensive mapping of the antigenic peptide repertoire during bacterial infection

Rupert MayerTeresa MaiaKatie BoucherBart VandekerckhoveFrancis Impens

Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice

Marlies BallegeerKelly Van LooverenSteven TimmermansMelanie EggermontSofie VandevyverFabien Henri TheryKaren DendonckerJolien SouffriauJolien VandewalleLise Van Wyngene et al.

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

GSyellow, a multifaceted tag for functional protein analysis in monocot and dicot plants

Nienke BesbruggeJelle Van LeeneDominique EeckhoutBernard CannootShubhada Rajabhau KulkarniNancy De WinneGeert PersiauEveline Van De SlijkeMichiel BontinckStijn Aesaert et al.

A1 Journal Article in PLANT PHYSIOLOGY

Impairment of angiogenesis by fatty acid synthase inhibition involves mTOR malonylation

Ulrike BruningFrancisco Morales-RodriguezJoanna KaluckaJermaine GoveiaFederico TavernaKarla CS QueirozCharlotte DuboisAnna Rita CantelmoRongyuan ChenStefan Loroch et al.

A1 Journal Article in CELL METABOLISM

Infection reveals a modification of SIRT2 critical for chromatin association

Jorge M PereiraChristine ChevalierThibault ChazeQuentin GianettoFrancis ImpensMariette MatondoPascale CossartMélanie A Hamon

A1 Journal Article in CELL REPORTS

Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination

M SteklovS PandolfiMF BaiettiA BatiukP CaraiP NajmM ZhangH JangF RenziY Cai et al.

A1 Journal Article in SCIENCE

N-terminal acetylation levels are maintained during acetyl-CoA deficiency in Saccharomyces cerevisiae

Sylvia VarlandHenriette AksnesFedor KryuchkovFrancis ImpensDelphi Van HaverVeronique JonckheereMathias ZieglerKris GevaertPetra Van DammeThomas Arnesen

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

NAA80 is actin’s N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility

Adrian DrazicHenriette AksnesMichaël MarieMalgorzata BoczkowskaSylvia VarlandEvy TimmermanHåvard FoynNina GlomnesGrzegorz RebowskiFrancis Impens et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomics reveals scope of mycolactone-mediated Sec61 blockade and distinctive stress signature

Jean-David MorelAnja O PaateroJiajie WeiJonathan W YewdellLaure Guenin-MacéDelphi Van HaverFrancis ImpensNatalia PietrosemoliVille O PaavilainenCaroline Demangel

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Quantitative proteomics and systems analysis of cultured H9C2 cardiomyoblasts during differentiation over time supports a ‘function follows form’ model of differentiation

Cynthia KankeuKylie ClarkeDelphi Van HaverKris GevaertFrancis ImpensAnna DittrichH Llewelyn RoderickEgle PassanteHeinrich J Huber

A1 Journal Article in MOLECULAR OMICS

Rapid remodeling of the host epithelial cell proteome by the listeriolysin O pore-forming toxin

Julien Karim MaletFrancis ImpensFilipe CarvalhoMélanie Anne HamonPascale CossartDavid Ribet

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxElisa HeyrmanJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensIlkka Miinalainen et al.

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxElisa HeyrmanJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensIlkka Miinalainen et al.

The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages

Viacheslav MylkaJulie DeckersDariusz RatmanLode De CauwerJonathan ThommisRiet De RyckeFrancis ImpensClaude LibertJan TavernierWim Vanden Berghe et al.

A1 Journal Article in AUTOPHAGY

2017

A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics : the case of NPC1 deficiency

Arun Kumar Tharkeshwar RaghunathJesse TrekkerWendy VermeireJarne PauwelsRagna SannerudDavid A PriestmanDanielle te VruchteKatlijn VintsPieter BaatsenJean-Paul Decuypere et al.

A1 Journal Article in SCIENTIFIC REPORTS

Legionella pneumophila modulates mitochondrial dynamics to trigger metabolic repurposing of infected macrophages

Pedro EscollOk-Ryul SongFlávia VianaBernhard SteinerThibault LagacheJean-Christophe Olivo-MarinFrancis ImpensPriscille BrodinHubert HilbiCarmen Buchrieser

A1 Journal Article in CELL HOST & MICROBE

N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes

Francis ImpensNathalie RolhionLilliana RadoshevichChristophe BécavinMélodie DuvalJeffrey MellinFrancisco García del PortilloM Graciela PucciarelliAllison H WilliamsPascale Cossart

A1 Journal Article in NATURE MICROBIOLOGY

Phase separation of C9orf72 dipeptide repeats perturbs stress granule dynamics

Steven BoeynaemsElke BogaertDenes KovacsAlbert KonijnenbergEvy TimmermanAlex VolkovMainak GuharoyMathias De DeckerTom JaspersVeronica H Ryan et al.

A1 Journal Article in MOLECULAR CELL

Protease substrate profiling by N-terminal COFRADIC

An StaesPetra Van DammeEvy TimmermanBart RuttensElisabeth StesKris GevaertFrancis Impens

Bookchapter in Protein terminal profiling : methods and protocols

Quality control in mass spectrometry-based proteomics

Wout BittremieuxDavid L TabbFrancis ImpensAn StaesEvy TimmermanLennart MartensKris Laukens

A1 Journal Article in MASS SPECTROMETRY REVIEWS

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

Jeff E GrotzkePatrycja KozikJean-David MorelFrancis ImpensNatalia PietrosemoliPeter CresswellSebastian AmigorenaCaroline Demangel

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Legionella pneumophila genome evolved to accommodate multiple regulatory mechanisms controlled by the CsrA-system

Tobias SahrChristophe RusniokFrancis ImpensGiulia OlivaOdile SismeiroJean-Yves CoppéeCarmen Buchrieser

A1 Journal Article in PLOS GENETICS

2016

Intelligent mixing of proteomes for elimination of false positives in affinity purification-mass spectrometry

Sven EyckermanFrancis ImpensEmmy Van QuickelbergheNoortje SamynGiel VandemoorteleDelphine De SutterJan TavernierKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Mycolactone subverts immunity by selectively blocking the Sec61 translocon

L BaronAO PaateroJD MorelFrancis ImpensL Guenin-MacéS Saint-AuretN BlanchardR DillmannF NiangS Pellegrini et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2015

Fast profiling of protease specificity reveals similar substrate specificities for cathepsins K, L and S

Matej VizovišekRobert VidmarEmmy Van QuickelbergheFrancis ImpensUroš AndjelkovićBarbara SobotičVeronika StokaKris GevaertBoris TurkMarko Fonović

A1 Journal Article in PROTEOMICS

ISG15 counteracts Listeria monocytogenes infection

L RadoshevichFrancis ImpensD RibetJJ QueredaT Nam ThamMA NahoriH BierneO DussurgetJ Pizarro-CerdáKP Knobeloch et al.

A1 Journal Article in ELIFE

2014

Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli

Francis ImpensL RadoshevichP CossartD Ribet

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2013

A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis

Katrien Van ImpeJonas BethuyneSteven CoolFrancis ImpensDavid Ruano-GallegoOlivier De WeverBerlinda VanlooMarleen Van TroysKathleen LambeinCiska Boucherie et al.

A1 Journal Article in BREAST CANCER RESEARCH

A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection

Haig A. EskandarianFrancis ImpensMarie-Anne NahoriGuillaume SoubigouJean-Yves CoppéePascale CossartMelanie A. Hamon

A1 Journal Article in SCIENCE

Mapping proteolytic processing in the secretome of gastric cancer-associated myofibroblasts reveals activation of MMP-1, MMP-2, and MMP-3

Christopher HolmbergBart GhesquièreFrancis ImpensKris GevaertJ Dinesh KumarNicole CashSandhir KandolaPeter HegyiTimothy C WangGraham J Dockray et al.

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

The Online Protein Processing Resource (TOPPR) : a database and analysis platform for protein processing events

Niklaas ColaertDavy MaddeleinFrancis ImpensPetra Van DammeKim PlasmanKenny HelsensNiels HulstaertJoël VandekerckhoveKris GevaertLennart Martens

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Vpr content of HIV-1 virions determines infection of resting peripheral blood CD4⁺ lymphocytes

Anouk Van NuffelFrancis ImpensAnn BaeyensStijn VanheeWojciech WitkowskiElien VandermarliereHanne VanderstraetenEvelien NaessensKathleen Van LandeghemSophie Vermaut et al.

2012

A catalogue of putative HIV-1 protease host cell substrates

Francis ImpensEvy TimmermanAn StaesKathleen MoensKevin AriënBruno VerhasseltJoël VandekerckhoveKris Gevaert

A1 Journal Article in BIOLOGICAL CHEMISTRY

Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike

Magdalena WejdaFrancis ImpensNozomi TakahashiPetra Van DammeKris GevaertPeter Vandenabeele

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

The Apaf-1-binding protein Aven is cleaved by Cathepsin D to unleash its anti-apoptotic potential

IM MelzerSBM FernándezS BösserK LohrigU LewandrowskiD WoltersS KehrloesserM-L BrezniceanuAC TheosPM Irusta et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2011

m-Calpain activation in vitro does not require autolysis or subunit dissociation

Jordan S ChouFrancis ImpensKris GevaertPeter L Davies

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

N-Terminal combined fractional diagonal chromatographic (COFRADIC) analysis of the human platelet proteome

Francis ImpensKenny HelsensNiklaas ColaertLennart MartensJoël VandekerckhoveKris Gevaert

Bookchapter in Platelet proteomics : principles, analysis, and applications

Probing the efficiency of proteolytic events by positional proteomics

Kim PlasmanPetra Van DammeDion KaisermanFrancis ImpensKimberly DemeyerKenny HelsensMarc GoethalsPhillip I BirdJoël VandekerckhoveKris Gevaert

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Selecting protein N-terminal peptides by combined fractional diagonal chromatography

An StaesFrancis ImpensPetra Van DammeBart RuttensMarc GoethalsHans DemolEvy TimmermanJoël VandekerckhoveKris Gevaert

A1 Journal Article in NATURE PROTOCOLS

The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma

Pieter MestdaghAna-Karin BostromFrancis ImpensErik FredlundGert Van PeerPaquito De AntonelisKristoffer Von StedingkBart GhesquièreStefanie SchulteMichael Dews et al.

2010

A quantitative proteomics design for systematic identification of protease cleavage events

Francis ImpensNiklaas ColaertKenny HelsensBart GhesquièreEvy TimmermanPieter-Jan De BockBenjamin M ChainJoël VandekerckhoveKris Gevaert

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Listeria monocytogenes impairs SUMOylation for efficient infection

David RibetMelanie HamonEdith GouinMarie-Anne NahoriFrancis ImpensHelene Neyret-KahnKris GevaertJoël VandekerckhoveAnne DejeanPascale Cossart

A1 Journal Article in NATURE

mir-17-92 is a master regulator of TGFβ-pathway activity in neuroblastoma

Pieter MestdaghAnna-Karin BöstromFrancis ImpensErik FredlundKris Von StedingkBart GhesquièreStefanie SchlierfJohannes SchulteAlexander SchrammKris Gevaert et al.

MS-driven protease substrate degradomics

Francis ImpensNiklaas ColaertKenny HelsensKim PlasmanPetra Van DammeJoël VandekerckhoveKris Gevaert

A1 Journal Article in PROTEOMICS

Rover: a tool to visualize and validate quantitative proteomics data from different sources

Niklaas ColaertKenny HelsensFrancis ImpensJoël VandekerckhoveKris Gevaert

A1 Journal Article in PROTEOMICS

Studying in vitro and in vivo protease processing in models of cancer cell death and viral infection by N-terminal COFRADIC

Francis ImpensKris Gevaert

The miR-17-92 MicroRNA Cluster regulates multiple components of the TGF-beta Pathway in neuroblastoma

Pieter MestdaghAnna-Karin BostromFrancis ImpensErik FredlundGert Van PeerPasqualino De AntonellisKristoffer von StedingkBart GhesquièreStefanie SchulteMichael Dews et al.

A1 Journal Article in MOLECULAR CELL

Who gets cut during cell death?

Francis ImpensJoël VandekerckhoveKris Gevaert

A1 Journal Article in CURRENT OPINION IN CELL BIOLOGY

2009

Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity

Dieter DemonPetra Van DammeTom Vanden BergheAnnelies DeceuninckJoost Van DurmeJelle VerspurtenKenny HelsensFrancis ImpensMagdalena WejdaJoost Schymkowitz et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

2008

Mechanistic insight into taxol-induced cell death

Francis ImpensPetra Van DammeHans DemolJozef Van DammeJoël VandekerckhoveKris Gevaert

A1 Journal Article in ONCOGENE

Protein processing characterized by a gel-free proteomics approach

Petra Van DammeFrancis ImpensJoël VandekerckhoveKris Gevaert

Bookchapter in Functional proteomics, part III

Stable isotopic labeling in proteomics

Kris GevaertFrancis ImpensBart GhesquièrePetra Van DammeAnja LambrechtsJoël Vandekerckhove

A1 Journal Article in PROTEOMICS

2007

A la carte proteomics with an emphasis on gel-free techniques

Kris GevaertPetra Van DammeBart GhesquièreFrancis ImpensLennart MartensKenny HelsensJoël Vandekerckhove

A1 Journal Article in PROTEOMICS

Applications of diagonal chromatography for proteome-wide characterization of protein modifications and activity-based analyses

Kris GevaertFrancis ImpensPetra Van DammeBart GhesquièreXavier HanoulleJoël Vandekerckhove

A1 Journal Article in FEBS JOURNAL