Research Explorer

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Researcher

Francis Combes

Awards & Distinctions

15 Results

2021

Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs

Zifu ZhongSéan Mc CaffertyLisa OpsomerHaixiu WangHanne HuysmansJoyca De TemmermanStefan LienenklausJoão Portela CataniFrancis CombesNiek Sanders

A1 Journal Article in MOLECULAR THERAPY

Corticosteroids and mRNA vaccines : a word of caution

Zifu ZhongFrancis CombesNiek Sanders

A1 Journal Article in MOLECULAR THERAPY

In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation

Séan Mc CaffertyJoyca De TemmermanTasuku KitadaJacob R. BecraftRon WeissDarrell J. IrvineMathias DevreeseSiegrid De BaereFrancis CombesNiek Sanders

A1 Journal Article in MOLECULAR THERAPY

Squaric ester-based, pH-degradable nanogels : modular nanocarriers for safe, systemic administration of toll-like receptor 7/8 agonistic immune modulators

Anne HuppertsbergLeonard KapsZifu ZhongSascha SchmittJudith StickdornKim DeswarteFrancis CombesChristian CzyschJana De VriezeSabah Kasmi et al.

A1 Journal Article in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

2020

Imidazoquinoline-conjugated degradable coacervate conjugate for local cancer immunotherapy

Hui LiSimon Van HerckYongjun LiuYanyun HaoXiaochu DingLutz NuhnZifu ZhongFrancis CombesNiek SandersStefan Lienenklaus et al.

A1 Journal Article in ACS BIOMATERIALS SCIENCE & ENGINEERING

Immune cells as tumor drug delivery vehicles

Francis CombesEvelyne MeyerNiek Sanders

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2019

Improving the repeatability and efficacy of intradermal electroporated self-replicating mRNA

Hanne HuysmansJoyca De TemmermanZifu ZhongSéan Mc CaffertyFrancis CombesFreddy HaesebrouckNiek Sanders

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

Migration and distribution of systemically injected mononuclear phagocytes in tumor-bearing mice

Francis CombesNiek SandersEvelyne Meyer

Mononuclear but not polymorphonuclear phagocyte depletion increases circulation times and improves mammary tumor-homing efficiency of donor bone marrow-derived monocytes

Francis CombesAlexandros Marios SofiasSéan Mc CaffertyHanne HuysmansJoyca De TemmermanSjoerd HakEvelyne MeyerNiek Sanders

A1 Journal Article in CANCERS

2018

Nanoparticle-conjugate TLR7/8 agonist localized immunotherapy provokes safe antitumoral responses

Lutz NuhnStefaan De KokerSandra Van LintZifu ZhongJoão Portela CataniFrancis CombesKim DeswarteYupeng LiBart LambrechtStefan Lienenklaus et al.

A1 Journal Article in ADVANCED MATERIALS

Off-target and tumor-specific accumulation of monocytes, macrophages and myeloid-derived suppressor cells after systemic injection

Francis CombesSéan Mc CaffertyEvelyne MeyerNiek Sanders

A1 Journal Article in NEOPLASIA

mRNA therapeutics deliver a hopeful message

Zifu ZhongSéan Mc CaffertyFrancis CombesHanne HuysmansJoyca De TemmermanArlieke GitselsDaisy VanrompayJoão Portela CataniNiek Sanders

A1 Journal Article in NANO TODAY

2017

Evaluation of a xenogeneic vascular endothelial growth factor-2 vaccine in two preclinical metastatic tumor models in mice

Sofie DeniesBregje LeymanHanne HuysmansFrancis CombesSéan Mc CaffertyLaetitia CiccheleroMarjan SteppeJoyca De TemmermanNiek Sanders

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY

In vitro exploration of a myeloid-derived suppressor cell line as vehicle for cancer gene therapy

Sofie DeniesFrancis CombesCynthia GhekiereSéan Mc CaffertyLaetitia CiccheleroNiek Sanders

A1 Journal Article in CANCER GENE THERAPY

2015

Eigenschappen en toekomstperspectieven van mesenchymale stamcellen bij honden

Francis CombesEvelien de BakkerCatharina De SchauwerEvelyne Meyer

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT