Research Explorer

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Researcher

Filip Van Nieuwerburgh

281 Results

2022

ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation

Richard de ReuverSimon VerdonckEvelien DierickJosephine NemegeerEline HessmannMaude JansGillian BlanckeFilip Van NieuwerburghLars VereeckeGeert van LooWim DeclercqPeter VandenabeeleJonathan Maelfait

A1 Journal Article in NATURE

Bringing science to the scene : novel strategies for portable DNA profiling

Olivier TytgatFilip Van NieuwerburghDieter Deforce

Cas9 targeted nanopore sequencing with enhanced variant calling improves CYP2D6-CYP2D7 hybrid allele genotyping

Kaat RubbenLaurentijn TillemanKoen DeserrannoOlivier TytgatDieter DeforceFilip Van Nieuwerburgh

U Journal Article in PLOS Genetics

Continuous activation of the IL-17F driven inflammatory pathway in acute and chronic digital dermatitis lesions in dairy cattle

Anne-Sofie VermeerschPeter GeldhofRichard DucatelleYannick GansemansFilip Van NieuwerburghDieter DeforceGeert Opsomer

A1 Journal Article in SCIENTIFIC REPORTS

Haplotyping pharmacogenes using TLA combined with Illumina or Nanopore sequencing

Laurentijn TillemanKaat RubbenWim Van CriekingeDieter DeforceFilip Van Nieuwerburgh

U Journal Article in Scientific Reports

Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts

Krishna PavaniTim MeeseOsvaldo Américo Bogado PascottiniXiaoyuan LinLuc PeelmanFilip Van NieuwerburghDieter DeforceAnnekatrien BoelBjörn HeindryckxKelly TillemanAnn Van SoomBart GadellaAn HendrixKatrien Smits

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lycopene supplementation to serum-free maturation medium improves in vitro bovine embryo development and quality and modulates embryonic transcriptomic profile

Osvaldo Américo Bogado PascottiniDaniel Angel VelezNima AzariDolatabadKrishna PavaniGretania ResidiwatiFilip Van NieuwerburghAnn Van Soom

A1 Journal Article in ANTIOXIDANTS

Metabolism and health effects of rare sugars in a CACO-2/HepG2 coculture model

Amar Daniël Emanuel Van LaarCharlotte GrootaertFilip Van NieuwerburghDieter DeforceTom DesmetKoen BeerensJohn Van Camp

A1 Journal Article in NUTRIENTS

Metallothioneins alter macrophage phenotype and represent novel therapeutic targets for acetaminophen-induced liver injury

Lindsey DevisscherSanne Van CampenhoutSander LefereSarah RaevensLaurentijn TillemanFilip Van NieuwerburghAnne HoorensAnja GeertsDebby LaukensHans Van Vlierberghe

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

Microbial diversity and antimicrobial susceptibility in endotracheal tube biofilms recovered from mechanically ventilated COVID-19 patients

Frits van CharanteAnneleen WiemePetra RigoleEvelien De CanckLisa OstynLucia GrassiDieter DeforceAurélie CrabbéPeter VandammeMarie JoossensFilip Van NieuwerburghPieter DepuydtTom Coenye

A2 Journal Article in BIOFILM

Multigenerational DNA methylation responses to copper exposure in daphnia : potential targets for epigenetic biomarkers?

Filip Van NieuwerburghJana Asselman

A1 Journal Article in CHEMOSPHERE

Nanopore sequencing of a forensic combined STR and SNP multiplex

Olivier TytgatSonja SkevinDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

PIWI proteins play an antiviral role in Lepidopteran cell lines

Filip Van Nieuwerburgh

A1 Journal Article in VIRUSES-BASEL

Phasing of the entire CYP2D6 locus with CRISPR-Cas9 enriched Nanopore sequencing

Laurentijn TillemanKaat RubbenFilip Van Nieuwerburgh

Profiling the aerobic window of horses in response to training by means of a modified lactate minimum speed test : flatten the curve

Lorie De MaréBerit BoshuizenCarmen Vidal Moreno de VegaConstance De meeûsLukas PlanckeYannick GansemansFilip Van NieuwerburghDieter DeforceMaarten OosterlinckCatherine Delesalle

A1 Journal Article in FRONTIERS IN PHYSIOLOGY

QueSTR probes : Quencher-labeled RNase H2-dependent probes for short tandem repeat genotyping

Olivier TytgatSonja SkevinDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SENSORS AND ACTUATORS B-CHEMICAL

RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Carolina de Carvalho NunesLisa DepestelLiselot MusLouis DelhayeAmber LouwagieMuhammad RishfiFanny De VloedEllen SandersAline EggermontSarah-Lee BekaertWouter Van LoockeJan Willem BekGivani DewynSiebe LoontiensGert Van IsterdaelBieke DecaestekerLaurentijn TillemanFilip Van NieuwerburghVanessa VermeirssenChristophe Van NesteBart GhesquièreSteven GoossensSven EyckermanKatleen De PreterBram De WildeKaat DurinckFranki Speleman

U Journal Article in Science Advances

Signatures of polygenic adaptation align with genome-wide methylation patterns in wild strawberry plants

Filip Van Nieuwerburgh

A1 Journal Article in NEW PHYTOLOGIST

TXNIP promotes human NK cell development but is dispensable for NK cell functionality

Eva PersynSigrid WahlenLaura KiekensSylvie TaveirneWouter Van LoockeEls Van AmmelFilip Van NieuwerburghTom TaghonBart VandekerckhovePieter Van VlierbergheGeorges Leclercq

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

Sigrid WahlenFilip MatthijssensWouter Van LoockeSylvie TaveirneLaura KiekensEva PersynEls Van AmmelZenzi De VosStijn De MunterFilip Van NieuwerburghTom TaghonBart VandekerckhovePieter Van VlierbergheGeorges Leclercq

A1 Journal Article in ELIFE

Transcriptional dynamics of gametogenesis in the green seaweed Ulva mutabilis identifies an RWP-RK transcription factor linked to reproduction

Xiaojie LiuJonas BlommeKenny BogaertSofie D'hondtDieter DeforceFilip Van NieuwerburghOlivier De Clerck

A1 Journal Article in BMC PLANT BIOLOGY

Veterinarians’ competence in applying basic genetic principles and daily implementation of clinical genetics : a study in a university environment

Evelien BogaertsLuc PeelmanFilip Van NieuwerburghJimmy SaundersBart Broeckx

A1 Journal Article in JOURNAL OF VETERINARY MEDICAL EDUCATION

2021

A case of phage therapy against pandrug-resistant Achromobacter xylosoxidans in a 12-year-old lung-transplanted cystic fibrosis patient

Maia MerabishviliLeen Van SimaeyHans DuyvejonckStefan VermeulenYannick GansemansFilip Van NieuwerburghMario Vaneechoutte

A1 Journal Article in VIRUSES-BASEL

ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation

Richard de ReuverEvelien DierickBartosz WiernickiKatrien StaesLeen SeysEllen De MeesterTuur MuyldermansAlexander BotzkiBart LambrechtFilip Van NieuwerburghPeter VandenabeeleJonathan Maelfait

A1 Journal Article in CELL REPORTS

Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells

Swati MishraJasin TaelmanMina PopovicLaurentijn TillemanEvi DuthooMargot Van der JeughtDieter DeforceFilip Van NieuwerburghBjörn MentenPetra De SutterAnnekatrien BoelSusana Marina Chuva de Sousa LopesBjörn Heindryckx

A1 Journal Article in STEM CELLS

Annelid genomes : Enchytraeus crypticus, a soil model for the innate (and primed) immune system

Yannick GansemansFilip Van Nieuwerburgh

A1 Journal Article in LAB ANIMAL

Cell-based non-invasive prenatal testing : circulating trophoblast enrichment and genetic analysis

Jana WeymaereFilip Van NieuwerburghDieter Deforce

Changes in DNA methylation in Arabidopsis thaliana plants exposed over multiple generations to gamma radiation

Filip Van Nieuwerburgh

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models

Helena DegrooteSander LefereBart VanderborghtTim MeeseFilip Van NieuwerburghXavier VerhelstAnja GeertsHans Van VlierbergheLindsey Devisscher

A2 Journal Article in ONCOTARGET

Circulating fetal trophoblast enrichment and single cell genetic analysis in the context of cell-based non-invasive prenatal testing

Ann-Sophie Vander PlaetsenFilip Van NieuwerburghDieter Deforce

Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences

Panagiotis StamatiadisAnnekatrien BoelGwenny CosemansMina PopovicBieke BekaertRamesh GuggillaMaoxing TangPetra De SutterFilip Van NieuwerburghBjörn MentenDominic StoopSusana Marina Chuva de Sousa LopesPaul CouckeBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION

Comparative genomics of Flavobacterium columnare unveils novel insights in virulence and antimicrobial resistance mechanisms

Annelies DeclercqLaurentijn TillemanYannick GansemansChloë De WitteFreddy HaesebrouckFilip Van NieuwerburghAnnemie Decostere

A1 Journal Article in VETERINARY RESEARCH

Detection of cytosine methylation in Burkholderia cenocepacia by single- molecule real- time sequencing and whole- genome bisulfite sequencing

Ian VandenbusscheAndrea SassFilip Van NieuwerburghTom Coenye

A1 Journal Article in MICROBIOLOGY-SGM

Digital polymerase chain reaction for assessment of mutant mitochondrial carry-over after nuclear transfer for In Vitro fertilization

Olivier TytgatWillem van SnippenbergAnnekatrien BoelYannick GansemansMichiel Van HerpSofie SymoensWim TrypsteenDieter DeforceBjörn HeindryckxPaul CouckeWard De SpiegelaereFilip Van Nieuwerburgh

A1 Journal Article in CLINICAL CHEMISTRY

Effect of overconditioning on the hepatic global gene expression pattern of dairy cows at the end of pregnancy

Osvaldo Américo Bogado PascottiniJenne De KosterFilip Van NieuwerburghMario Van PouckeLuc PeelmanVeerle FievezGeert Opsomer

A1 Journal Article in JOURNAL OF DAIRY SCIENCE

Effects of aleurone supplementation on glucose-insulin metabolism and gut microbiome in untrained healthy horses

Berit BoshuizenCarmen Vidal Moreno de VegaLorie De MaréConstance De meeûsYannick GansemansDieter DeforceFilip Van NieuwerburghCatherine Delesalle

A1 Journal Article in FRONTIERS IN VETERINARY SCIENCE

Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm

Laurentijn TillemanFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Enrichment of circulating trophoblasts from maternal blood using laminar microscale vortices

Ann-Sophie Vander PlaetsenJana WeymaereOlivier TytgatDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in PRENATAL DIAGNOSIS

Genetic responses of metabolically active limnospira indica strain PCC 8005 exposed to gamma-radiation during its lifecycle

Tim MeeseFilip Van Nieuwerburgh

A1 Journal Article in MICROORGANISMS

Genetics and epigenetics in clinical veterinary medicine : new approaches to deal with problems related to diagnostics and screening

Evelien BogaertsBart BroeckxJimmy SaundersLuc PeelmanFilip Van Nieuwerburgh

HES1 and HES4 have non-redundant roles downstream of Notch during early human T-cell development

Matthias De DeckerMarieke LavaertJuliette RoelsLaurentijn TillemanBart VandekerckhoveGeorges LeclercqFilip Van NieuwerburghPieter Van VlierbergheTom Taghon

A1 Journal Article in HAEMATOLOGICA

Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensFilip Van NieuwerburghDieter DeforceWouter Van LoockePieter Van VlierbergheJan PhilippéBarbara De Moerloose

A1 Journal Article in SCIENTIFIC REPORTS

MYCN-induced nucleolar stress drives an early senescence-like transcriptional program in hTERT-immortalized RPE cells

Sofia ZanottiSuzanne VanhauwaertChristophe Van NesteVolodimir OlexioukJolien Van LaereJoni Van der MeulenLiselot MusKaat DurinckLaurentijn TillemanDieter DeforceFilip Van NieuwerburghBieke DecaestekerFranki Speleman

A1 Journal Article in SCIENTIFIC REPORTS

Pharmacogenetics in clinical practice : current level of knowledge among Flemish physicians and pharmacists

Ahmed Edris MohamedAnna VanoverscheldeFilip Van NieuwerburghLies Lahousse

A1 Journal Article in PHARMACOGENOMICS JOURNAL

Pre-weaning inulin supplementation alters the ileal transcriptome in pigs regarding lipid metabolism

Dieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in VETERINARY SCIENCES

Profiling the aerobic window (AW) of horses in response to training by means of a new LMS (lactate minimum speed) test : flatten the curve

Lorie De MaréBerit BoshuizenCarmen Vidal Moreno de VegaConstance De meeûsLukas PlanckeYannick GansemansFilip Van NieuwerburghDieter DeforceCatherine Delesalle

RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia

Filip MatthijssensBéatrice LintermansWouter Van LoockeJuliette RoelsSofie PeirsLisa DemoenTim PietersLindy ReunesTim LammensBarbara De MoerlooseFilip Van NieuwerburghDieter DeforceMartijn RisseeuwSerge Van CalenberghSteven GoossensPieter Van Vlierberghe

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

Rare modifier variants alter the severity of cardiovascular disease in pseudoxanthoma elasticum : identification of novel candidate modifier genes and disease pathways through mixture of effects analysis

Eva De VilderPaul CouckeFilip Van NieuwerburghOlivier Vanakker

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions

Liselot MusStéphane Van HaverMina PopovicWim TrypsteenSteve LefeverEva JacobsEllen SandersChristophe Van NesteSuzanne VanhauwaertBieke DecaestekerDieter DeforceFilip Van NieuwerburghPieter MestdaghJo VandesompeleBjörn MentenKatleen De PreterBjörn HeindryckxKaat DurinckFranki Speleman

A1 Journal Article in GENES CHROMOSOMES & CANCER

STRide probes : single-labeled short tandem repeat identification probes

Olivier TytgatDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in BIOSENSORS & BIOELECTRONICS

T-BET and EOMES accelerate and enhance functional differentiation of human natural killer cells

Laura KiekensWouter Van LoockeSylvie TaveirneSigrid WahlenEva PersynEls Van AmmelZenzi De VosFilip Van NieuwerburghTom TaghonPieter Van VlierbergheBart VandekerckhoveGeorges Leclercq

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

TEAD4 regulates trophectoderm differentiation upstream of CDX2 in human preimplantation embryos

Panagiotis StamatiadisAnnekatrien BoelGwenny CosemansFilip Van NieuwerburghBjörn MentenPetra De SutterDominic Stoop

The genome of the extremophile Artemia provides insight into strategies to cope with extreme environments

Stephanie De VosStephane RombautsLouis CoussementWannes DermauwMarnik VuylstekePatrick SorgeloosFilip Van NieuwerburghParisa NorouzitallabThomas Van LeeuwenTim De MeyerGilbert Van StappenYves Van de PeerPeter Bossier

A1 Journal Article in BMC GENOMICS

The impact of maternal and piglet low protein diet and their interaction on the porcine liver transcriptome around the time of weaning

Kikianne KroeskeDieter DeforceFilip Van NieuwerburghMarc HeyndrickxSam Millet

A1 Journal Article in VETERINARY SCIENCES

Untangling the structural and molecular mechanisms underlying colour and rapid colour change in a lizard, Agama atra

Michaël NicolaïLiliana D'Alba AltamiranoJonathan GoldenbergYannick GansemansFilip Van NieuwerburghMatthew Shawkey

A1 Journal Article in MOLECULAR ECOLOGY

2020

Adjuvanting allergen extracts for sublingual immunotherapy : calcitriol downregulates CXCL8 production in primary sublingual epithelial cells

Michael PelstCharlotte WallaeysHilde De RoosterYannick GansemansFilip Van NieuwerburghBert DevriendtEric Cox

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

Juliette RoelsMorgan ThénozStien De ConinckLisa DemoenLien ProvezAnna KuchmiySteven StrubbeLindy ReunesTim PietersFilip MatthijssensWouter Van LoockeTim LammensBarbara De MoerlooseDieter DeforceFilip Van NieuwerburghSteven GoossensTom TaghonPieter Van Vlierberghe

A2 Journal Article in BLOOD CANCER DISCOVERY

Comparative study of preimplantation development following distinct assisted oocyte activation protocols in a PLC-zeta knockout mouse model

Minerva Ferrer BuitragoLaurentijn TillemanVanessa ThysAnnekatrien BoelFilip Van NieuwerburghDieter DeforceLuc LeybaertPetra De SutterBjörn Heindryckx

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development

Juliette RoelsAnna KuchmiyMatthias De DeckerSteven StrubbeMarieke LavaertKai Ling LiangGeorges LeclercqBart VandekerckhoveFilip Van NieuwerburghPieter Van VlierbergheTom Taghon

A1 Journal Article in NATURE IMMUNOLOGY

Distinct transcriptome signatures of Helicobacter suis and Helicobacter heilmannii strains upon adherence to human gastric epithelial cells

Helena BerlamontChloë De WitteEva BauwensHannah Min JouRichard DucatelleEllen De MeesterYannick GansemansDieter DeforceFilip Van NieuwerburghFreddy HaesebrouckAnnemieke Smet

A1 Journal Article in VETERINARY RESEARCH

Does the mode of dispersion determine the properties of dispersed Pseudomonas aeruginosa biofilm cells?

Jasper WilleAndrea SassFilip Van NieuwerburghKevin BraeckmansTom Coenye

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Ecological divergence of wild strawberry DNA methylation patterns at distinct spatial scales

Dieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in MOLECULAR ECOLOGY

Effect of oral aleurone supplementation on glucose and insulin dynamics of horses in training

Berit BoshuizenConstance De meeûsLorie De MaréCarmen Vidal Moreno de VegaYannick GansemansFilip Van NieuwerburghDieter DeforceCatherine Delesalle

Extracellular vesicles spread the RNA interference signal of Tribolium castaneum TcA cells

Yannick GansemansFilip Van Nieuwerburgh

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

First draft genome assembly of the desert locust, Schistocerca gregaria

Lieven SterckJia LiZhen LiYannick GansemansDieter DeforceFilip Van NieuwerburghYves Van de Peer

A2 Journal Article in F1000RESEARCH

Human thymic CD10+ PD-1+ intraepithelial lymphocyte precursors acquire interleukin-15 responsiveness at the CD1a– CD95+ CD28– CCR7– developmental stage

Lore BillietGlenn GoetgelukSarah BonteStijn De MunterLaurenz De CockMelissa PilleJoline IngelsHanne JansenKarin WeeningFilip Van NieuwerburghTessa KerreTom TaghonGeorges LeclercqBart Vandekerckhove

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Kinship analysis on single cells after whole genome amplification

Jana WeymaereAnn-Sophie Vander PlaetsenLaurentijn TillemanOlivier TytgatKaat RubbenDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Maternal recognition of pregnancy in the horse : are MicroRNAs the secret messengers?

Katrien SmitsYannick GansemansLaurentijn TillemanFilip Van NieuwerburghMargot Van de VeldeIlse GeritsCyrillus VerversKim RoelsJan GovaereLuc PeelmanDieter DeforceAnn Van Soom

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Murine induced pluripotent stem cell‐derived neuroimmune cell culture models emphasize opposite immune-effector functions of interleukin 13-primed microglia and macrophages in terms of neuroimmune toxicity

Tim MeeseFilip Van Nieuwerburgh

A1 Journal Article in GLIA

Myeloid IRE1a deletion alters hepatic macrophage phenotype and attenuates experimental non-alcoholic steatohepatitis-related hepatocellular carcinoma

Sanne Van CampenhoutLaurentijn TillemanSander LefereAnja GeertsXavier VerhelstFilip Van NieuwerburghHans Van VlierbergheLindsey Devisscher

Myeloid-specific IRE1alpha deletion reduces tumour development in a diabetic, non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model

Sanne Van CampenhoutLaurentijn TillemanSander LefereAster VandierendonckSarah RaevensXavier VerhelstAnja GeertsFilip Van NieuwerburghHans Van VlierbergheLindsey Devisscher

A1 Journal Article in METABOLISM-CLINICAL AND EXPERIMENTAL

Nanopore sequencing of a forensic STR multiplex reveals loci suitable for single-contributor STR profiling

Olivier TytgatYannick GansemansJana WeymaereKaat RubbenDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in GENES

Pan-cancer pharmacogenetics : targeted sequencing panels or exome sequencing?

Laurentijn TillemanBjörn HeindryckxDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in PHARMACOGENOMICS

Spatio-temporal patterns in the gene expression of the calanoid copepod Temora longicornis in the Belgian part of the North Sea

Ilias SemmouriKarel De SchamphelaereFilip Van NieuwerburghDieter DeforceColin JanssenJana Asselman

A1 Journal Article in MARINE ENVIRONMENTAL RESEARCH

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

Sylvie TaveirneSigrid WahlenWouter Van LoockeLaura KiekensEva PersynEls Van AmmelKatrien De MulderJuliette RoelsLaurentijn TillemanFilip Van NieuwerburghTessa KerreTom TaghonPieter Van VlierbergheBart VandekerckhoveGeorges Leclercq

A1 Journal Article in BLOOD

Validation of a new LMS (lactate minimum speed) exercise test for optimal assessment of the aerobic window of sport horses

Lorie De MaréBerit BoshuizenConstance De meeûsLukas PlanckeCarmen Vidal Moreno de VegaFilip Van NieuwerburghDieter DeforceCatherine Delesalle

Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis

Juan FraireGaëlle HouthaeveJing LiuLaurens RaesLotte VermeulenStephan StremerschToon BransSarah De KeulenaerFilip Van NieuwerburghRiet De RyckeJo VandesompelePieter MestdaghKoen RaemdonckStefaan De SmedtKevin Braeckmans

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2019

A multi-omics analysis of the grapevine pathogen Lasiodiplodia theobromae reveals that temperature affects the expression of virulence- and pathogenicity-related genes

Laurentijn TillemanYves Van de PeerDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Bovine embryo-secreted microRNA-30c is a potential non-invasive biomarker for hampered preimplantation developmental competence

Xiaoyuan LinEvy BeckersSéan Mc CaffertyYannick GansemansKatarzyna Joanna Szymańska-VandendriesscheKrishna PavaniJoão Portela CataniFilip Van NieuwerburghDieter DeforcePetra De SutterAnn Van SoomLuc Peelman

A1 Journal Article in FRONTIERS IN GENETICS

Comparative analysis of different nuclear transfer techniques to prevent the transmission of mitochondrial DNA variants

Maoxing TangYannick GansemansMargot Van der JeughtAnnekatrien BoelPanagiotis StamatiadisRudy Van CosterDieter DeforceFilip Van NieuwerburghPetra De SutterBjörn Heindryckx

Comparative analysis of different nuclear transfer techniques to prevent the transmission of mitochondrial DNA variants

Maoxing TangRamesh GuggillaYannick GansemansMargot Van der JeughtAnnekatrien BoelMina PopovicPanagiotis StamatiadisMinerva Ferrer BuitragoVanessa ThysRudy Van CosterDieter DeforcePetra De SutterFilip Van NieuwerburghBjörn Heindryckx

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Comparison of seven contemporary pharmacogenetic assays with the PharmGKB database

Laurentijn TillemanDieter DeforceFilip Van Nieuwerburgh

Contemporary pharmacogenetic assays in view of the PharmGKB database

Laurentijn TillemanJana WeymaereBjörn HeindryckxDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in PHARMACOGENOMICS

Dual RNA sequencing of Vitis vinifera during Lasiodiplodia theobromae infection unveils host-pathogen interactions

Laurentijn TillemanYves Van de PeerDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Emended description of Gardnerella vaginalis and description of Gardnerella leopoldii sp. nov., Gardnerella piotii sp. nov. and Gardnerella swidsinskii sp. nov., with delineation of 13 genomic species within the genus Gardnerella

Mario VaneechoutteLeen Van SimaeyYannick GansemansFilip Van NieuwerburghPiet Cools

A1 Journal Article in INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Feasibility of single-cell analysis of model cancer and foetal cells in blood after isolation by cell picking

Ann-Sophie Vander PlaetsenFilip Van Nieuwerburgh

A2 Journal Article in TUMOR BIOLOGY

Forensic lab-on-a-chip DNA analysis

Senne CornelisDieter DeforceFilip Van Nieuwerburgh

Forensic tri-allelic SNP genotyping using nanopore sequencing

Senne CornelisYannick GansemansAnn-Sophie Vander PlaetsenJana WeymaereSander WillemsDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Gain of 20q11.21 in human pluripotent stem cells impairs TGF-β-dependent neuroectodermal commitment

Laurentijn TillemanFilip Van Nieuwerburgh

A1 Journal Article in STEM CELL REPORTS

Generation of virus- and dsRNA-derived siRNAs with species-dependent length in insects

Luoluo WangOlivier ChristiaensKaat CappelleYannick GansemansFilip Van NieuwerburghGuy Smagghe

A1 Journal Article in VIRUSES-BASEL

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

Gloria MilaniFilip MatthijssensWouter Van LoockeKaat DurinckJuliette RoelsSofie PeirsMorgan ThénozTim PietersLindy ReunesBéatrice LintermansNiels VandammeTim LammensNadine Van RoyFilip Van NieuwerburghDieter DeforceBarbara De MoerlooseYves BenoitSteven GoossensGeert BerxPieter Van Vlierberghe

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Genome-wide stress responses to copper and arsenic in a field population of Daphnia

Jana AsselmanIlias SemmouriFilip Van NieuwerburghDieter DeforceKarel De Schamphelaere

A1 Journal Article in ENVIRONMENTAL SCIENCE & TECHNOLOGY

Honey bee predisposition of resistance to ubiquitous mite infestations

Bart BroeckxLina De SmetKevin MaebeMikalaï KhalenkowMario Van PouckeGuy SmaggheDieter DeforceFilip Van NieuwerburghLuc PeelmanDirk de Graaf

A1 Journal Article in SCIENTIFIC REPORTS

Increased primordial germ cell (PGC) specification from human embryonic stem cells (hESC) derived in Activin A

Swati MishraMargot Van der JeughtMina PopovicJasin TaelmanEvi DuthooKatarzyna Joanna Szymańska-VandendriesschePetra De SutterLaurentijn TillemanFilip Van NieuwerburghAnnekatrien BoelBjörn Heindryckx

Influence of microbiota in the susceptibility of parasitic wasps to abamectin insecticide : deep sequencing, esterase and toxicity tests

Ivan MeeusAnnelies BillietFilip Van NieuwerburghDieter DeforcePeter VandammeGuy Smagghe

A1 Journal Article in PEST MANAGEMENT SCIENCE

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

dr. Sandrine HerbeletEmma Clare HobbsCarl LachatFilip Van NieuwerburghRoosmarijn VandenbrouckeFrederik BerrevoetPieter Van Dessel

A1 Journal Article in DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION

Marine biogenics in sea spray : a new source of pharmaceuticals and nutritionals

Jana AsselmanEmmanuel Van AckerLaurentijn TillemanFilip Van NieuwerburghJan MeesKarel De SchamphelaereColin Janssen

Marine biogenics in sea spray aerosols interact with the mTOR signaling pathway

Jana AsselmanEmmanuel Van AckerLaurentijn TillemanFilip Van NieuwerburghJan MeesKarel De SchamphelaereColin Janssen

A1 Journal Article in SCIENTIFIC REPORTS

Rejections in an non-purpose bred assistance dog population : reasons, consequences and methods for screening

Evelien BogaertsChristel MoonsFilip Van NieuwerburghLuc PeelmanJimmy SaundersBart Broeckx

A1 Journal Article in PLOS ONE

Silicon µPCR chip for forensic STR profiling with hybeacon probe melting curves

Senne CornelisOlivier TytgatYannick GansemansAnn-Sophie Vander PlaetsenDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Small RNA NcS27 co-regulates utilization of carbon sources in Burkholderia cenocepacia J2315

Andrea SassStijn De WaeleSimon DaledBart DevreeseDieter DeforceFilip Van NieuwerburghTom Coenye

A1 Journal Article in MICROBIOLOGY-SGM

The inflammasome pathway is involved in PXE through IL1B upregulation in patients with a severe cardiovascular PXE phenotype

Eva De VilderPaul CouckeAnne De PaepeFilip Van NieuwerburghOlivier Vanakker

The transcriptome of the marine calanoid copepod Temora longicornis under heat stress and recovery

Ilias SemmouriJana AsselmanFilip Van NieuwerburghDieter DeforceColin JanssenKarel De Schamphelaere

A1 Journal Article in MARINE ENVIRONMENTAL RESEARCH

Transgenerational inheritance of DNA hypomethylation in Daphnia magna in response to salinity stress

João Alves BarbosaKarel De SchamphelaereFilip Van NieuwerburghDieter DeforceJana Asselman

Truncating SLC12A6 variants cause different clinical phenotypes in humans and dogs

Mario Van PouckeKimberley SteeLaurien SonckEmmelie StockJo Van DorpeFilip Van NieuwerburghDieter DeforceLuc PeelmanLuc Van HamSofie BhattiBart Broeckx

A1 Journal Article in EUROPEAN JOURNAL OF HUMAN GENETICS

Uncovering low-level mosaicism in human embryonic stem cells using high throughput single cell shallow sequencing

Laurentijn TillemanFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Various Evolutionary Trajectories Lead to Loss of the Tobramycin-Potentiating Activity of the Quorum-Sensing Inhibitor Baicalin Hydrate in Burkholderia cenocepacia Biofilms

Andrea SassLisa SlachmuyldersHeleen Van AckerIan VandenbusscheLisa OstynMona BovéAurélie CrabbéFilip Van NieuwerburghEmmanuel AbatihTom Coenye

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

WNT inhibition and increased fibroblast growth factor signaling promotes derivation of less heterogeneous primed human embryonic stem cells, compatible with differentiation

Jasin TaelmanMina PopovicLaurentijn TillemanSharat WarrierMargot Van der JeughtBjörn MentenDieter DeforcePetra De SutterFilip Van NieuwerburghBjörn HeindryckxSusana Marina Chuva de Sousa Lopes

A1 Journal Article in STEM CELLS AND DEVELOPMENT

YtrA(Sa), a GntR-family transcription factor, represses two genetic loci encoding membrane proteins in Sulfolobus acidocaldarius

Laurentijn TillemanFilip Van Nieuwerburgh

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

2018

A different gut microbial community between larvae and adults of a wild bumblebee nest (Bombus pascuorum)

Anneleen ParmentierIvan MeeusFilip Van NieuwerburghDieter DeforcePeter VandammeGuy Smagghe

A1 Journal Article in INSECT SCIENCE

A prokaryotic-eukaryotic relation in the fat body of Bombus terrestris

Anneleen ParmentierAnnelies BillietGuy SmagghePeter VandammeDieter DeforceFilip Van NieuwerburghIvan Meeus

A1 Journal Article in ENVIRONMENTAL MICROBIOLOGY REPORTS

Analysis of shared heritability in common disorders of the brain

Filip Van Nieuwerburgh

A1 Journal Article in SCIENCE

Chromosomal mosaicism in human blastocysts : the ultimate challenge of preimplantation genetic testing?

Mina PopovicAnnelies DheedeneJasin TaelmanLien DhaenensFilip Van NieuwerburghDieter DeforceEtienne Van den AbbeelPetra De SutterBjörn MentenBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION

Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background

Sabitri GhimireMargot Van der JeughtJitesh NeupaneMina PopovicFilip Van NieuwerburghPieter MestdaghJo VandesompeleDieter DeforceBjörn MentenPetra De SutterBjörn Heindryckx

A1 Journal Article in SCIENTIFIC REPORTS

Coumarin reduces virulence and biofilm formation in Pseudomonas aeruginosa by affecting quorum sensing, type III secretion and C-di-GMP levels

Yunhui ZhangAndrea SassHeleen Van AckerJasper WilleBruno VerhasseltFilip Van NieuwerburghAurélie CrabbéTom Coenye

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Crossing borders to mitigate mycotoxins : where microbiology, poly-omics and crop protection meet

Laura De MetsLeen De GelderFilip Van NieuwerburghKris Audenaert

Decreased susceptibility of Streptococcus anginosus to vancomycin in a multispecies biofilm is due to increased thickness of the cell wall

Sarah TavernierAndrea SassMichiel De BruyneFemke BaekeRiet De RyckeAurélie CrabbéIlse VandecandelaereFilip Van NieuwerburghTom Coenye

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Effect of β-adrenergic receptor agents on cardiac structure and function and whole-body gene expression in Daphnia magna

Jana AsselmanKarel De SchamphelaereFilip Van NieuwerburghDieter Deforce

A1 Journal Article in ENVIRONMENTAL POLLUTION

Elucidation of the mechanism behind the potentiating activity of baicalin against Burkholderia cenocepacia biofilms

Lisa SlachmuyldersHeleen Van AckerGilles BrackmanAndrea SassFilip Van NieuwerburghTom Coenye

A1 Journal Article in PLOS ONE

Intraobserver and interobserver agreement on the radiographical diagnosis of canine cranial cruciate ligament rupture

Evelien BogaertsElke Van der VekensGeert VerhoevenHilde De RoosterBernadette Van RyssenYves SamoyNausikaa DevriendtMiléva BertalStephanie ScheemaekerJeroen VerstrekenLaurien FeenstraLuc PeelmanFilip Van NieuwerburghJimmy SaundersBart Broeckx

A1 Journal Article in VETERINARY RECORD

Massively parallel sequencing of micro-manipulated cells targeting a comprehensive panel of disease-causing genes : a comparative evaluation of upstream whole-genome amplification methods

Lieselot DeleyeYannick GansemansDieter De ConinckFilip Van NieuwerburghDieter Deforce

A1 Journal Article in PLOS ONE

Microbial degradation of zearalenone by Actinobacteria : mind the toxicity

Laura De MetsKris AudenaertMarthe De BoevreArnau Vidal CorominasFilip Van NieuwerburghLeen De Gelder

Multiplex STR amplification sensitivity in a silicon microchip

Senne CornelisYannick GansemansAnn-Sophie Vander PlaetsenDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

PLCz knock-out sperm reveals the sole effect of altering calcium signals during assisted oocyte activation on later mouse embryogenesis

Minerva Ferrer BuitragoLaurentijn TillemanVanessa ThysFilip Van NieuwerburghLuc LeybaertPetra De SutterDieter DeforceBjörn Heindryckx

Photothermally triggered endosomal escape and its influence on transfection efficiency of gold-functionalized JetPEI/pDNA nanoparticles

Lotte VermeulenJuan FraireLaurens RaesEllen De MeesterSarah De KeulenaerFilip Van NieuwerburghStefaan De SmedtKatrien RemautKevin Braeckmans

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Positive human health effects of sea spray aerosols : molecular evidence from exposed lung cell lines

Jana AsselmanEmmanuel Van AckerLaurentijn TillemanFilip Van NieuwerburghJan MeesKarel De SchamphelaereColin Janssen

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

Renate De SmedtSofie PeirsJulie MorscioFilip MatthijssensJuliette RoelsLindy ReunesBéatrice LintermansSteven GoossensTim LammensNadine Van RoyFilip Van NieuwerburghDieter DeforceBarbara De MoerlooseYves BenoitPieter Van Vlierberghe

A1 Journal Article in HAEMATOLOGICA

Proteins involved in embryo-maternal interaction around the signalling of maternal recognition of pregnancy in the horse

Katrien SmitsSander WillemsKatleen Van SteendamMargot Van de VeldeCyrillus VerversKim RoelsJan GovaereFilip Van NieuwerburghLuc PeelmanDieter DeforceAnn Van Soom

A1 Journal Article in SCIENTIFIC REPORTS

Short tandem repeat analysis after whole genome amplification of single B-lymphoblastoid cells

Lieselot DeleyeAnn-Sophie Vander PlaetsenJana WeymaereDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

Bieke DecaestekerGeertrui DeneckerChristophe Van NesteWouter Van LoockeCarolina de Carvalho NunesFanny De VloedPauline DepuydtKaren VerboomDries RombautSiebe LoontiensJolien De WynKaat DurinckDieter DeforceFilip Van NieuwerburghPieter MestdaghSuzanne VanhauwaertKatleen De PreterFranki Speleman

A1 Journal Article in NATURE COMMUNICATIONS

The Chara genome : secondary complexity and implications for plant terrestrialization

Lisa VanderstraetenStephane RombautsAssia SaltykovaFilip Van NieuwerburghDieter DeforceYves Van de PeerDominique Van Der Straeten

A1 Journal Article in CELL

The molecular basis for positive health effects of sea spray on human lung cells

Jana AsselmanEmmanuel Van AckerLaurentijn TillemanFilip Van NieuwerburghJan MeesKarel De SchamphelaereColin Janssen

The presence of extracellular microRNAs in the media of cultured Drosophila cells

Yannick GansemansFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

The small RNA ncS35 regulates growth in Burkholderia cenocepacia J2315

Sanne KiekensAndrea SassFilip Van NieuwerburghDieter DeforceTom Coenye

A1 Journal Article in MSPHERE

Transcriptional landscape changes during human embryonic stem cell derivation

Sharat WarrierJasin TaelmanLaurentijn TillemanMargot Van der JeughtGalbha DuggalSylvie LiermanMina PopovicAnn Van SoomLuc PeelmanFilip Van NieuwerburghDieter DeforceSusana Marina Chuva de Sousa LopesPetra De SutterBjörn Heindryckx

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Transgenerational inheritance of DNA hypomethylation in Daphnia magna in response to salinity stress

Karel De SchamphelaereFilip Van NieuwerburghDieter DeforceJana Asselman

A1 Journal Article in ENVIRONMENTAL SCIENCE & TECHNOLOGY

Unravelling the molecular pathways responsible for sex determination in humans

Jasin TaelmanMina PopovicLaurentijn TillemanMargot Van der JeughtDieter DeforcePetra De SutterFilip Van NieuwerburghBjörn Heindryckx

2017

Characterization of the emerging zoonotic pathogen Arcobacter thereius by whole genome sequencing and comparative genomics

Francesca RovettoAurélien CarlierKoen IlleghemsFilip Van NieuwerburghKurt Houf

A1 Journal Article in PLOS ONE

Colony contact contributes to the diversity of gut bacteria in bumblebees (Bombus terrestris)

Annelies BillietIvan MeeusFilip Van NieuwerburghDieter DeforceGuy Smagghe

A1 Journal Article in INSECT SCIENCE

Comprehensive comparison of inner cell mass and trophectoderm reveals the complex nature of chromosomal mosaicism in human embryos

Mina PopovicAnnelies DheedeneMargot Van der JeughtFilip Van NieuwerburghDieter DeforcePetra De SutterEtienne Van den AbbeelBjörn MentenBjörn Heindryckx

Direct comparison of distinct naive pluripotent states in human embryonic stem cells

Sharat WarrierMargot Van der JeughtGalbha DuggalLaurentijn TillemanJasin TaelmanMina PopovicSylvie LiermanSusana Marina Chuva de Sousa LopesAnn Van SoomLuc PeelmanFilip Van NieuwerburghDieter De ConinckBjörn MentenPieter MestdaghJo VandesompeleDieter DeforcePetra De SutterBjörn Heindryckx

A1 Journal Article in NATURE COMMUNICATIONS

Discovery of the leinamycin family of natural products by mining actinobacterial genomes

Yannick GansemansFilip Van Nieuwerburgh

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of aleurone on equine fecal microbiome and glucose metabolism in non-training horses

Berit BoshuizenConstance De meeûsFilip Van NieuwerburghDieter DeforceLaura Van HauweCatherine Delesalle

Epigenetic sampling effects : nephrectomy modifies the clear cell renal cell cancer methylome

Christophe Van NesteWim Van CriekingeDieter DeforceFilip Van NieuwerburghTim De Meyer

A1 Journal Article in CELLULAR ONCOLOGY

Flagging false positives following untargeted LCMS characterization of histone PTM combinations

Sander WillemsMaarten DhaenensElisabeth GovaertLaura De ClerckPaulien MeertChristophe Van NesteFilip Van NieuwerburghDieter Deforce

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Forensic SNP genotyping using nanopore MinION sequencing

Senne CornelisYannick GansemansLieselot DeleyeDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Massively parallel sequencing in preimplantation and prenatal genetic diagnosis

Lieselot DeleyeFilip Van NieuwerburghDieter Deforce

Metabolic activity, urease production, antibiotic resistance and virulence in dual species biofilms of Staphylococcus epidermidis and Staphylococcus aureus

Ilse VandecandelaereFilip Van NieuwerburghDieter DeforceTom Coenye

A1 Journal Article in PLOS ONE

Microbial community profiling of fresh basil and pitfalls in taxonomic assignment of enterobacterial pathogenic species based upon 16S rRNA

Siele CeuppensDieter De ConinckFilip Van NieuwerburghMieke Uyttendaele

A1 Journal Article in INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

Steven GoossensSofie PeirsWouter Van LoockeFilip MatthijssensNiels VandammeFilip Van NieuwerburghDieter DeforceGeert BerxPieter Van Vlierberghe

A1 Journal Article in BLOOD

Origins of Human Embryonic Stem Cell Fate: Role of the Post Inner Cell Mass Intermediate

Sharat WarrierMina PopovicJasin TaelmanLaurentijn TillemanSylvie LiermanAnn Van SoomLuc PeelmanFilip Van NieuwerburghDieter DeforcePetra De SutterBjörn Heindryckx

Performance of four modern whole genome amplification methods for copy number variant detection in single cells

Lieselot DeleyeLaurentijn TillemanAnn-Sophie Vander PlaetsenSenne CornelisDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Preimplantation genetic diagnosis for chromosomal rearrangements with the use of array comparative genomic hybridization at the blastocyst stage

Annelies DheedeneBjörn HeindryckxFilip Van NieuwerburghDieter DeforcePetra De SutterBjörn MentenEtienne Van den Abbeel

A1 Journal Article in FERTILITY AND STERILITY

RMNE calculation in forensic profiles with a high number of loci and allelic drop-outs using polynomial expansion

Sander WillemsSenne CornelisYannick GansemansBart BroeckxDieter De ConinckChristophe Van NesteMaarten DhaenensDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods

Ann-Sophie Vander PlaetsenLieselot DeleyeSenne CornelisLaurentijn TillemanFilip Van NieuwerburghDieter Deforce

A1 Journal Article in SCIENTIFIC REPORTS

The transcriptome of Mycobacterium tuberculosis in a lipid-rich dormancy model through RNAseq analysis

Diana Angelica Aguilar AyalaLaurentijn TillemanFilip Van NieuwerburghDieter DeforceJuan Carlos PalominoPeter VandammeAnandi Martin

A1 Journal Article in SCIENTIFIC REPORTS

Unraveling the zearalenone degradation pathway using a poly-omics approach : first results

Laura De MetsKris AudenaertArnau Vidal CorominasFilip Van NieuwerburghLeen De Gelder

Wnt inhibition during hESC culture provides an improved pluripotent state starting point for directed differentiation

Jasin TaelmanLaurentijn TillemanFilip Van NieuwerburghSharat WarrierMina PopovicMargot Van der JeughtDieter DeforcePetra De SutterBjörn HeindryckxSusana Marina Chuva de Sousa Lopes

2016

Assessing the impact of minimizing arginine conversion in fully defined SILAC culture medium in human embryonic stem cells

Ellen ScheerlinckKatleen Van SteendamSimon DaledElisabeth GovaertLiesbeth VossaertPaulien MeertFilip Van NieuwerburghAnn Van SoomLuc PeelmanPetra De SutterBjörn HeindryckxMaarten DhaenensDieter Deforce

A1 Journal Article in PROTEOMICS

Divergence between the highly virulent zoonotic pathogen Helicobacter heilmannii and its closest relative, the low-virulence 'Helicobacter ailurogastricus' sp. nov.

Myrthe JoostenPeter VandammeFilip Van NieuwerburghKatharina D'HerdeWim Van Den BroeckBram FlahouDieter DeforceRichard DucatelleFreddy HaesebrouckAnnemieke Smet

A1 Journal Article in INFECTION AND IMMUNITY

Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer

Christophe Van NesteDieter DeforceFilip Van NieuwerburghGeert TrooskensWim Van CriekingeTim De Meyer

A1 Journal Article in ONCOTARGET

Forensic Loci Allele Database (FLAD) : automatically generated, permanent identifiers for sequenced forensic alleles

Christophe Van NesteWim Van CriekingeDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Impact of sugar syrup and pollen diet on the bacterial diversity in the gut of indoor-reared bumblebees (Bombus terrestris)

Annelies BillietIvan MeeusFilip Van NieuwerburghDieter DeforceGuy Smagghe

A1 Journal Article in APIDOLOGIE

In vivo study of Dicer-2-mediated immune response of the small interfering RNA pathway upon systemic infections of virulent and avirulent viruses in Bombus terrestris

Jinzhi NiuGuy SmaggheDieter De ConinckFilip Van NieuwerburghDieter DeforceIvan Meeus

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Massive parallel sequencing uncovers chromosomal mosaicism in human embryonic stem cells in both primed and naive culture conditions

Mina PopovicMargot Van der JeughtFranki SpelemanFilip Van NieuwerburghPetra De SutterBjörn MentenBjörn Heindryckx

Microbial diversity and metabolite composition of Belgian red-brown acidic ales

Isabel SnauwaertSanne RoelsFilip Van NieuwerburghAnita Van LandschootPeter Vandamme

A1 Journal Article in INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detection using massively parallel sequencing

Lieselot DeleyeDieter De ConinckAnnelies DheedenePetra De SutterBjörn MentenDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

Preimplantation genetic diagnosis (PGD) for translocation carriers using whole genome screening by microarray analysis at the blastocyst stage

Annelies DheedeneIlse De CrooBjörn HeindryckxLieselot DeleyeFilip Van NieuwerburghDieter DeforcePetra De SutterBjörn MentenEtienne Van den Abbeel

Statistical framework for detection of genetically modified organisms based on Next Generation Sequencing

Sander WillemsMarie-Alice FraitureDieter DeforceMarc De LooseFilip Van Nieuwerburgh

A1 Journal Article in FOOD CHEMISTRY

Strain prioritization and genome mining for enediyne natural products

Yannick GansemansFilip Van Nieuwerburgh

A1 Journal Article in MBIO

Suboptimal culture conditions induce more deviations in gene expression in male than female bovine blastocysts

Sonia Heras GarcíaDieter De ConinckMario Van PouckeKaren GoossensOsvaldo Américo Bogado PascottiniFilip Van NieuwerburghDieter DeforcePetra De SutterJo LeroyLuc PeelmanAnn Van Soom

A1 Journal Article in BMC GENOMICS

The equine embryo influences immune related gene expression in the oviduct

Katrien SmitsDieter De ConinckFilip Van NieuwerburghJan GovaereMario Van PouckeLuc PeelmanDieter DeforceAnn Van Soom

A1 Journal Article in BIOLOGY OF REPRODUCTION

The quorum sensing inhibitor hamamelitannin increases antibiotic susceptibility of Staphylococcus aureus biofilms by affecting peptidoglycan biosynthesis and eDNA release

Gilles BrackmanKoen BreyneRiet De RyckeArno VermoteFilip Van NieuwerburghEvelyne MeyerSerge Van CalenberghTom Coenye

A1 Journal Article in SCIENTIFIC REPORTS

Toward the most ideal case-control design with related and unrelated dogs in whole-exome sequencing studies

Bart BroeckxFrank CoopmanGeert VerhoevenSarah De KeulenaerEllen De MeesterValérie BavegemsPascale SmetsBernadette Van RyssenFilip Van NieuwerburghDieter Deforce

A1 Journal Article in ANIMAL GENETICS

Uncovering the novel role of mTORC2 subunit of the PI3K/AKT/mTORC pathway in establishing naive pluripotency in human embryonic stem cells

Sharat WarrierMargot Van der JeughtGalbha DuggalJasin TaelmanSylvie LiermanSusana Marina Chuva de Sousa LopesAnn Van SoomLuc PeelmanFilip Van NieuwerburghDieter De ConinckBjörn MentenDieter DeforcePetra De SutterBjörn Heindryckx

Unique long non-coding RNA expression signature in ETV6/RUNX1-Driven B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerlooseWouter Van LoockeAnnelynn WallaertFilip Van NieuwerburghDieter DeforceNadine Van RoyFranki SpelemanYves BenoitTim LammensPieter Van Vlierberghe

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerlooseWouter Van LoockeAnnelynn WallaertHetty HelsmoortelFilip Van NieuwerburghDieter DeforceNadine Van RoyFranki SpelemanYves BenoitTim LammensPieter Van Vlierberghe

A1 Journal Article in ONCOTARGET

2015

16S rRNA Amplicon sequencing demonstrates that indoor-reared bumblebees (Bombus terrestris) harbor a core subset of bacteria normally associated with the wild host

Ivan MeeusLaurian ParmentierAnnelies BillietKevin MaebeFilip Van NieuwerburghDieter DeforcePeter VandammeGuy Smagghe

A1 Journal Article in PLOS ONE

A doubling of microphytobenthos biomass coincides with a tenfold increase in denitrifier and total bacterial abundances in intertidal sediments of a temperate estuary

Helen DecleyreKim HeylenKoen SabbeBjorn TytgatDieter DeforceFilip Van NieuwerburghCarl Van ColenAnne Willems

A1 Journal Article in PLOS ONE

An heuristic filtering tool to identify phenotype-associated genetic variants applied to human intellectual disability and canine coat colors

Bart BroeckxFrank CoopmanGeert VerhoevenTim BosmansIngrid GielenWalter DingemanseJimmy SaundersDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in BMC BIOINFORMATICS

Canine whole exome sequencing : hip, hip, hurray?: the quest for genetic solutions for phenotypical problems

Bart BroeckxDieter DeforceFrank CoopmanGeert VerhoevenFilip Van Nieuwerburgh

Challenges and opportunities in the investigation of unexplained intellectual disability using family-based whole-exome sequencing

Filip Van Nieuwerburgh

A1 Journal Article in CLINICAL GENETICS

Comparative analysis of different culture conditions inducing naive pluripotency in human embryonic stem cells

Sharat WarrierGalbha DuggalJasin TaelmanSylvie LiermanAnn Van SoomLuc PeelmanFilip Van NieuwerburghDieter De ConinckBjörn MentenDieter DeforceMargot Van der JeughtPetra De SutterBjörn Heindryckx

Derivation conditions affect pluripotency and differentiation propensity of mouse embryonic stem cells

Sabitri GhimireMargot Van der JeughtJitesh NeupaneFilip Van NieuwerburghDieter DeforceSusana Marina Chuva de Sousa LopesPetra De SutterBjörn Heindryckx

Differential transcriptome analysis of the common shrimp Crangon crangon: special focus on the nuclear receptors and RNAi-related genes

Olivier ChristiaensChristophe Van NesteNa YuRuben De WildeFilip Van NieuwerburghDieter DeforceGuy Smagghe

A1 Journal Article in GENERAL AND COMPARATIVE ENDOCRINOLOGY

Effect of multiple allelic drop-outs in forensic RMNE calculations

Christophe Van NesteDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Efficiency of exome sequencing for the molecular diagnosis of Pseudoxanthoma Elasticum

Mohammad Jakir HosenFilip Van NieuwerburghWouter SteyaertDieter DeforceAnne De PaepePaul CouckeOlivier Vanakker

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Forensic massively parallel sequencing data analysis tool: implementation of MyFLq as a standalone web- and Illumina BaseSpace®-application

Christophe Van NesteYannick GansemansDieter De ConinckDavid Van HoofstatWim Van CriekingeDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Genome sequence of Devriesea agamarum, isolated from agamid lizards with dermatitis

Roel HaesendonckFilip Van NieuwerburghFreddy HaesebrouckDieter DeforceFrank PasmansAn Martel

A2 Journal Article in MICROBIOLOGY RESOURCE ANNOUNCEMENTS

Genome-wide transcription start site profiling in biofilm-grown Burkholderia cenocepacia J2315

Andrea SassHeleen Van AckerFilip Van NieuwerburghDieter DeforceTom Coenye

A1 Journal Article in BMC GENOMICS

Heuristic filtering of sequencing variants with the R-package "Mendelian"

Bart BroeckxFrank CoopmanGeert VerhoevenDieter DeforceFilip Van Nieuwerburgh

Improved canine exome designs, featuring ncRNAs and increased coverage of protein coding genes

Bart BroeckxFrank CoopmanGeert VerhoevenSarah De KeulenaerEllen De MeesterTim BosmansIngrid GielenHenri van BreeBernadette Van RyssenJimmy SaundersFilip Van NieuwerburghDieter Deforce

A1 Journal Article in SCIENTIFIC REPORTS

Novel phenotypes and genes in pseudoxanthoma elasticum-related soft tissue mineralization: results of an integrative approach

Eva De VilderMohammad Jakir HosenPaul CouckeAnne De PaepeFilip Van NieuwerburghOlivier Vanakker

OSC2 and CYP716A14v2 catalyze the biosynthesis of triterpenoids for the cuticle of aerial organs of Artemisia annua

Tessa MosesJacob PollierSandra SoetaertMarie-Laure ErffelinckFilip Van NieuwerburghRobin Vanden BosscheDieter DeforceAlain Goossens

A1 Journal Article in PLANT CELL

Phospho-iTRAQ : assessing isobaric labels for the large-scale study of phosphopeptide stoichiometry

Pieter GlibertPaulien MeertKatleen Van SteendamFilip Van NieuwerburghDieter De ConinckLennart MartensMaarten DhaenensDieter Deforce

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Porting forensic DNA analysis to deep sequencing

Christophe Van NesteDieter DeforceWim Van CriekingeFilip Van Nieuwerburgh

Prevalence of gender nonconformity in Flanders, Belgium

Eva Van CaenegemKatrien WierckxEls ElautAnn BuysseAlexis DewaeleFilip Van NieuwerburghGuy T'Sjoen

A1 Journal Article in ARCHIVES OF SEXUAL BEHAVIOR

Shallow whole genome sequencing is well suited for the detection of chromosomal aberrations in human blastocysts

Lieselot DeleyeAnnelies DheedeneDieter De ConinckTom SanteBjörn HeindryckxEtienne Van den AbbeelPetra De SutterDieter DeforceBjörn MentenFilip Van Nieuwerburgh

A1 Journal Article in FERTILITY AND STERILITY

Transcriptome analysis of Bombyx mori larval midgut during persistent and pathogenic cytoplasmic polyhedrosis virus infection

Filip Van NieuwerburghDieter DeforceGuy Smagghe

A1 Journal Article in PLOS ONE

Validation of a sensitive DNA walking strategy to characterise unauthorised GMOs using model food matrices mimicking common rice products

Marie-Alice FraitureMarc De LooseFilip Van NieuwerburghDieter Deforce

A1 Journal Article in FOOD CHEMISTRY

Viral small-RNA analysis of Bombyx mori larval midgut during persistent and pathogenic cytoplasmic polyhedrosis virus infection

Filip Van NieuwerburghDieter DeforceGuy Smagghe

A1 Journal Article in JOURNAL OF VIROLOGY

Whole exome sequencing as a novel tool for the detection of modifier genes in Pseudoxanthoma elasticum

Eva De VilderFilip Van NieuwerburghDieter DeforcePaul CouckeAnne De PaepeOlivier Vanakker

Whole exome sequencing as a novel tool for the detection of modifier genes in pseudoxanthoma elasticum

Eva De VilderFilip Van NieuwerburghDieter DeforceAnne De PaepeOlivier Vanakker

Whole exome sequencing the dog

Bart BroeckxFrank CoopmanGeert VerhoevenSarah De KeulenaerEllen De MeesterTim BosmansValérie BavegemsIngrid GielenHenri van BreeBernadette Van RyssenJimmy SaundersFilip Van NieuwerburghDieter Deforce

Whole genome amplification with SurePlex results in better copy number alteration detection using sequencing data compared to the MALBAC method

Lieselot DeleyeDieter De ConinckTom SanteAnnelies DheedeneBjörn HeindryckxEtienne Van den AbbeelPetra De SutterBjörn MentenDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in SCIENTIFIC REPORTS

2014

Autovaccination confers protection against Devriesea agamarum associated septicemia but not dermatitis in bearded dragons (Pogona vitticeps)

Tom HellebuyckKatleen Van SteendamDieter DeforceMark BlooiFilip Van NieuwerburghEvelien BullaertRichard DucatelleFreddy HaesebrouckFrank PasmansAn Martel

A1 Journal Article in PLOS ONE

Detailed method description for noninvasive monitoring of differentiation status of human embryonic stem cells

Ellen ScheerlinckKatleen Van SteendamMado VandewoestyneTrees LepezVeerle GobinPaulien MeertLiesbeth VossaertFilip Van NieuwerburghAnn Van SoomLuc PeelmanBjörn HeindryckxPetra De SutterMaarten DhaenensDieter Deforce

A1 Journal Article in ANALYTICAL BIOCHEMISTRY

Development and performance of a targeted whole exome sequencing enrichment kit for the dog (Canis Familiaris Build 3.1)

Bart BroeckxFrank CoopmanGeert VerhoevenValérie BavegemsSarah De KeulenaerEllen De MeesterFilip Van NieuwerburghDieter Deforce

A1 Journal Article in SCIENTIFIC REPORTS

Draft genome sequence of methicillin-resistant Staphylococcus epidermidis strain ET-024, isolated from an endotracheal tube biofilm of a mechanically ventilated patient

Ilse VandecandelaereFilip Van NieuwerburghDieter DeforceHans NelisTom Coenye

A4 Journal Article in GENOME ANNOUNCEMENTS

Illumina sequencing of 15 deafness genes using fragmented amplicons

Filip Van NieuwerburghSarah De KeulenaerJoachim De SchrijverJo VandesompeleWim Van CriekingePaul CouckeDieter Deforce

A2 Journal Article in BMC RESEARCH NOTES

Library construction for next-generation sequencing: overviews and challenges

Filip Van Nieuwerburgh

A1 Journal Article in BIOTECHNIQUES

My-Forensic-Loci-queries (MyFLq) framework for analysis of forensic STR data generated by massive parallel sequencing

Christophe Van NesteMado VandewoestyneWim Van CriekingeDieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Perfrin, a novel bacteriocin associated with netB positive Clostridium perfringens strains from broilers with necrotic eneteritis

Leen TimbermontLina De SmetFilip Van NieuwerburghGonzalez Van DriesscheFreddy HaesebrouckRichard DucatelleDieter DeforceBart DevreeseFilip Van Immerseel

A1 Journal Article in VETERINARY RESEARCH

Presence and analysis of plasmids in human and animal associated Arcobacter species

Laid DouidahLieven De ZutterFilip Van NieuwerburghDieter DeforceAnne-Marie Van Den AbeeleKurt Houf

A1 Journal Article in PLOS ONE

Quantification of integrated HIV DNA by repetitive-sampling Alu-HIV PCR on the basis of Poisson statistics

Ward De SpiegelaereEva MalatinkováFilip Van NieuwerburghPeter MessiaenLinos Vandekerckhove

A1 Journal Article in CLINICAL CHEMISTRY

Quantitative proteomics to characterize specific histone H2A proteolysis in chronic lymphocytic leukemia and the myeloid THP-1 cell line

Pieter GlibertLiesbeth VossaertKatleen Van SteendamStijn LambrechtFilip Van NieuwerburghFritz OffnerMaarten DhaenensDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Retrospective study of the impact of miniSTRs on forensic DNA profiling of touch DNA samples

Filip Van NieuwerburghDavid Van HoofstatChristophe Van NesteDieter Deforce

A1 Journal Article in SCIENCE & JUSTICE

Safety assessment of the butyrate-producing Butyricicoccus pullicaecorum strain 25-3T, a potential probiotic for patients with inflammatory bowel disease, based on oral toxicity tests and whole genome sequencing

Marjan SteppeFilip Van NieuwerburghGriet VercauterenFilip BoyenVenessa EeckhautDieter DeforceFreddy HaesebrouckRichard DucatelleFilip Van Immerseel

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

The BCESM genomic region contains a regulator involved in quorum sensing and persistence in Burkholderia cenocepacia J2315

Heleen Van AckerEvelien De CanckFilip Van NieuwerburghAndrea SassDieter DeforceHans NelisTom Coenye

A1 Journal Article in FUTURE MICROBIOLOGY

The effects of positioning, reason for screening and the referring veterinarian on prevalence estimates of canine hip dysplasia

Bart BroeckxGeert VerhoevenFrank CoopmanTim BosmansIngrid GielenJimmy SaundersHenri van BreeBernadette Van RyssenVanessa VerbekeKatleen Van SteendamFilip Van NieuwerburghDieter Deforce

A1 Journal Article in VETERINARY JOURNAL

2013

Ancient dispersal of the human fungal pathogen Cryptococcus gattii from the Amazon rainforest

Filip Van NieuwerburghDieter Deforce

A1 Journal Article in PLOS ONE

Caspase-14-deficient mice are more prone to the development of parakeratosis

Esther HosteGeertrui DeneckerBarbara GilbertFilip Van NieuwerburghBob AsselberghRiet De RyckeDieter DeforcePeter VandenabeeleWim Declercq

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Differential transcriptome analysis of glandular and filamentous trichomes in Artemisia annua

Sandra SoetaertChristophe Van NesteMado VandewoestyneAlain GoossensFilip Van NieuwerburghDieter Deforce

A1 Journal Article in BMC PLANT BIOLOGY

Genome sequence of Helicobacter heilmannii sensu stricto ASB1 isolated from the gastric mucosa of a kitten with severe gastritis

Annemieke SmetFilip Van NieuwerburghBram FlahouDieter DeforceRichard DucatelleFreddy Haesebrouck

A4 Journal Article in GENOME ANNOUNCEMENTS

Genome-wide association study of obsessive-compulsive disorder

Dieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in MOLECULAR PSYCHIATRY

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

Dieter DeforceFilip Van Nieuwerburgh

A1 Journal Article in PLOS GENETICS

PiTRAQ, a strategy to simultaneously correlate protein expression and phosphorylation stoichiometry between different samples: evaluation on different mass spectrometers

Pieter GlibertMaarten DhaenensPaulien MeertNiklaas ColaertFilip Van NieuwerburghLennart MartensDieter Deforce

Presence and potential of cell free DNA in different types of forensic samples

Mado VandewoestyneDavid Van HoofstatFilip Van NieuwerburghDieter Deforce

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Prevalence of genetic disorders in dogs from Belgium, the Netherlands and Germany

Bart BroeckxGeert VerhoevenTim BosmansIngrid GielenJimmy SaundersHenri van BreeFilip Van NieuwerburghBernadette Van RyssenKatleen Van SteendamDieter Deforce

Quantification of integrated HIV DNA by repetitive sampling Alu-HIV PCR and Poisson statistics

Ward De SpiegelaereEva MalatinkováFilip Van NieuwerburghLinos Vandekerckhove

The prevalence of nine genetic disorders in a dog population from Belgium, the Netherlands and Germany

Bart BroeckxFrank CoopmanGeert VerhoevenTim BosmansIngrid GielenJimmy SaundersSandra SoetaertHenri van BreeChristophe Van NesteFilip Van NieuwerburghBernadette Van RyssenElien VerelstKatleen Van SteendamDieter Deforce

A1 Journal Article in PLOS ONE

Transcriptome and small RNA analysis of larval midgut tissue persistently and acutely infected by cytoplasmic polyhedrosis virus (CPV) in the silkmoth Bombyx mori

Filip Van NieuwerburghGuy Smagghe

Trichomes, the key to an increased production of artemisinin in Artemisia annua

Sandra SoetaertDieter DeforceAlain GoossensFilip Van Nieuwerburgh

2012

Assessment of microbial diversity in biofilms recovered from endotracheal tubes using culture dependent and independent approaches

Ilse VandecandelaereNele MatthijsFilip Van NieuwerburghDieter DeforceLiesbet De BusHans NelisPieter DepuydtTom Coenye

A1 Journal Article in PLOS ONE

Catechol-O-methyltranferase gene expression is associated with response to citalopram in obsessive-compulsive disorder

Filip Van NieuwerburghDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE

Evaluation of a strategy for parallel protein phosphorylation and expression analysis

Pieter GlibertMaarten DhaenensPaulien MeertNiklaas ColaertFilip Van NieuwerburghLennart MartensDieter Deforce

Evaluation of three DNA extraction protocols for forensic STR typing after laser capture microdissection

Mado VandewoestyneFilip Van NieuwerburghDavid Van HoofstatDieter Deforce

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Fetal microchimeric cells in the blood of women with an autoimmune thyroid disease

Trees LepezMado VandewoestyneFilip Van NieuwerburghDieter Deforce

Forensic STR analysis using massive parallel sequencing

Christophe Van NesteFilip Van NieuwerburghDavid Van HoofstatDieter Deforce

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL-GENETICS

Full genome sequences of all nine Chlamydia psittaci genotype reference strains

Sarah Van LentDelphine Sylvie Anne BeeckmanFilip Van NieuwerburghDaisy Vanrompay

A1 Journal Article in JOURNAL OF BACTERIOLOGY

Illumina mate-paired DNA sequencing-library preparation using Cre-Lox recombination

Filip Van NieuwerburghDieter Deforce

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Laser capture microdissection in forensics

Mado VandewoestyneDavid Van HoofstatFilip Van NieuwerburghDieter Deforce

Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform

Sarah De KeulenaerJan HellemansSteve LefeverJean-Pierre RenardJoachim De SchrijverHendrik Van de VoordeFilip Van NieuwerburghDaisy FlamezFilip PattynBieke ScharlakenDieter DeforceSofie BekaertWim Van CriekingeJo VandesompelePaul Coucke

A1 Journal Article in BMC MEDICAL GENOMICS

Perfrin, a novel bacteriocin from a necrotic enteritis associated Clostridium perfringens strain

Leen TimbermontSofie GeeraertsLina De SmetFilip Van NieuwerburghGonzalez Van DriesscheFreddy HaesebrouckDieter DeforceBart DevreeseFilip Van Immerseel

Purification and characterization of Perfrin, a novel bacteriocin from a virulent Clostridium perfringens strain

Leen TimbermontLina De SmetAnouk LanckrietFilip Van NieuwerburghGonzalez Van DriesscheFreddy HaesebrouckRichard DucatelleDieter DeforceBart DevreeseFilip Van Immerseel

Relation between the FBN2 haplotype and phenotypical hip dysplasia

Bart BroeckxFrank CoopmanGeert VerhoevenTim BosmansIngrid GielenJimmy SaundersSandra SoetaertHenri van BreeFilip Van NieuwerburghBernadette Van RyssenDieter Deforce

Variations in the exome of the LNCaP prostate cancer cell line

Filip Van NieuwerburghDieter Deforce

A1 Journal Article in PROSTATE

2011

Directional RNA deep sequencing sheds new light on the transcriptional response of Anabaena sp strain PCC 7120 to combined-nitrogen deprivation

Filip Van Nieuwerburgh

A1 Journal Article in BMC GENOMICS

Dissection of the phytohormonal regulation of trichome formation and biosynthesis of the antimalarial compound artemisinin in Artemisia annua plants

Lies MaesFilip Van NieuwerburghJacob PollierSofie Vande CasteeleDirk InzéDieter DeforceAlain Goossens

A1 Journal Article in NEW PHYTOLOGIST

Fetal microchimeric cells in blood of women with an autoimmune thyroid disease

Trees LepezMado VandewoestyneShahid HussainFilip Van NieuwerburghJean KaufmanDieter Deforce

A1 Journal Article in PLOS ONE

Modification of citrulline residues with 2,3-butanedione facilitates their detection by liquid chromatography/mass spectrometry

Marlies De CeuleneerVanessa De WitKatleen Van SteendamFilip Van NieuwerburghKelly TillemanDieter Deforce

A1 Journal Article in RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Practical tools to implement massive parallel pyrosequencing of PCR products in next generation molecular diagnostics

Kim De LeeneerJoachim De SchrijverLieven ClementMachteld BaetensSteve LefeverSarah De KeulenaerWim Van CriekingeDieter DeforceFilip Van NieuwerburghSofie BekaertFilip PattynBram De WildePaul CouckeJo VandesompeleKathleen ClaesJan Hellemans

A1 Journal Article in PLOS ONE

Quantitative bias in Illumina TruSeq and a novel post amplification barcoding strategy for multiplexed DNA and small RNA deep sequencing

Filip Van NieuwerburghSandra SoetaertDieter Deforce

A1 Journal Article in PLOS ONE

Sources of DNA contamination and decontamination procedures in the forensic laboratory

Mado VandewoestyneDavid Van HoofstatSabine De GrooteNicky Van ThuyneSaskia HaerinckFilip Van NieuwerburghDieter Deforce

A2 Journal Article in INTERNATIONAL JOURNAL OF FORENSIC PRACTICE AND RESEARCH

Transcriptome analysis of apical and sub-apical cells of Artemisia annua trichomes with next-generation-sequencing

Sandra SoetaertFilip Van NieuwerburghAlain GoossensDieter Deforce

Whole genome sequence analysis of Helicobacter heilmannii

Annemieke SmetFilip Van NieuwerburghBram FlahouFrank PasmansDieter DeforceRichard DucatelleFreddy Haesebrouck

2010

Analysing 454 amplicon resequencing experiments using the modular and database oriented Variant Identification Pipeline

Joachim De SchrijverKim De LeeneerSteve LefeverNick SabbeFilip PattynFilip Van NieuwerburghPaul CouckeDieter DeforceJo VandesompeleSofie BekaertJan HellemansWim Van Criekinge

A1 Journal Article in BMC BIOINFORMATICS

Complete nucleotide sequence of CTX-M-15-plasmids from clinical Escherichia coli isolates: insertional events of transposons and insertion sequences

Annemieke SmetFilip Van NieuwerburghTom VandekerckhoveAn MartelDieter DeforcePatrick ButayeFreddy Haesebrouck

A1 Journal Article in PLOS ONE

Compulsivity in mouse strains homologous with chromosomes 7p and 15q linked tot obsessive-compulsive disorder

Filip Van NieuwerburghDieter Deforce

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

The role of the COMT Val158Met polymorphism in the phenotypic expression of obsessive-compulsive disorder

Filip Van NieuwerburghDieter Deforce

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

2009

Automatic detection of spermatozoa for laser capture microdissection

Mado VandewoestyneDavid Van HoofstatFilip Van NieuwerburghDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Impact of allelic dropout on evidential value of forensic DNA profiles

Filip Van NieuwerburghEls GoetghebeurMado VandewoestyneDieter Deforce

A1 Journal Article in BIOINFORMATICS

Metabolite analysis of laser captured apical and subapical cells of Artemisia annua trichomes

Sandra SoetaertFilip Van NieuwerburghSofie Vande CasteeleMado VandewoestyneAlain GoossensDieter Deforce

Phytohormonal regulation of gland formation and artemisinin biosynthesis in Artemisia annua

Filip Van NieuwerburghLies MaesSofie Vande CasteeleSandra SoetaertMarc Van MontaguDirk InzéDieter DeforceAlain Goossens

RMNE probability of Forensic DNA profiles with allelic drop-out

Filip Van NieuwerburghEls GoetghebeurMado VandewoestyneDieter Deforce

A2 Journal Article in Forensic science international. Genetics

Response to serotonin reuptake inhibitors in OCD is not influenced by common CYP2D6 polymorphisms

Filip Van NieuwerburghDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE

Suspension fluorescence in situ hybridization (S-FISH) combined with automatic detection and laser microdissection for STR profiling of male cells in male/female mixtures

Mado VandewoestyneDavid Van HoofstatFilip Van NieuwerburghDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF LEGAL MEDICINE

2008

Automatic detection of spermatozoa for laser capture microdissection

Mado VandewoestyneDavid Van HoofstatFilip Van NieuwerburghDieter Deforce

Response to paroxetine and venlafaxine in OCD is not determined by common CYP2D6 polymorphisms

Filip Van NieuwerburghDieter Deforce

Serotonin Related Genes Affect Antidepressant Treatment in Obsessive-Compulsive Disorder

Filip Van NieuwerburghDieter Deforce

A2 Journal Article in Progress in Neurotherapeutics and Neuropsychopharmacology

Serotonin related genes affect antidepressant treatment in obsessive-compulsive disorder

Filip Van NieuwerburghDieter Deforce

Bookchapter in Progress in Neurotherapeutics and Neuropsychopharmacology

Shorter CAG repeats in the androgen receptor gene may enhance hyperandrogenicity in polycystic ovary syndrome

Filip Van NieuwerburghMarc DhontDieter DeforcePetra De Sutter

A1 Journal Article in GYNECOLOGICAL ENDOCRINOLOGY

Shorter CAG repeats in the androgen receptor gene may enhance hyperandrogenicity in polycystic ovary syndrome (PCOS)

Filip Van NieuwerburghDominic StoopMarc DhontPetra De SutterDieter Deforce

2007

Gene discovery: Polymorphism association with obsessive-compulsive disorder and proteome analysis of Artemisia annua.

Filip Van Nieuwerburgh

Prediction of response to paroxetine and venlafaxine by serotonin-related genes in obsessive-compulsive disorder in a randomized, double-blind trial

Filip Van NieuwerburghDieter Deforce

A1 Journal Article in JOURNAL OF CLINICAL PSYCHIATRY

Virilizing clinical features of PCO patients with normal androgen levels may result from a shorter CAG repeat length of the androgen receptor gene

Filip Van NieuwerburghJan GerrisMarc DhontDieter DeforcePetra De Sutter

2006

Association between serotonergic candidate genes and specific phenotypes of obsessive compulsive disorder

Filip Van NieuwerburghDieter Deforce

A1 Journal Article in JOURNAL OF AFFECTIVE DISORDERS

Association between the dopamine D-2 receptor TaqI A2 allele and low activity COMT allele with obsessive-compulsive disorder in males

Filip Van NieuwerburghDieter Deforce

A1 Journal Article in EUROPEAN NEUROPSYCHOPHARMACOLOGY

Development and evaluation of different normalization strategies for gene expression studies in Candida albicans biofilms by real-time PCR

Heleen NailisTom CoenyeFilip Van NieuwerburghDieter DeforceHans Nelis

A1 Journal Article in BMC MOLECULAR BIOLOGY

Quantitation of artemisinin and its biosynthetic precursors in Artemisia annua L. by high performance liquid chromatography - electrospray quadrupole time-of-flight tandem mass spectrometry

Filip Van NieuwerburghSofie Vande CasteeleLies MaesAlain GoossensDirk InzéJan Van BocxlaerDieter Deforce

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

2005

Prediction of response to paroxetine and venlafaxine by serotonin related genes in obsessive-compulsive disorder

Filip Van NieuwerburghDieter Deforce