Research Explorer

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Researcher

Filip Dumont

Awards & Distinctions

40 Results

2006

Influence of deposition and spray pattern of nasal powders on insulin bioavailability

Eveline PringelsC CALLENSChris VervaetFilip DumontGuido SlegersP FOREMANJean Paul Remon

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Synthesis and HPLC-purification of [Br-77]TMC125-R165335 (etravirine), a new anti-HIV drug of the DAPY-NNRTI class

Bart De SpiegeleerFilip DumontKathelijne PeremansChristian BurvenichLieven Van VoorenJ ROSIERL BAERTP WIGERINCKGuido Slegers

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

2005

In vivo evaluation of [I-123]-4-iodo-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-benzamide: a potential sigma receptor ligand for SPECT studies

Ludovicus StaelensRuth OltenfreiterFilip DumontRN WATERHOUSEK VANDENBULCKEPeter BlanckaertRudi DierckxGuido Slegers

A1 Journal Article in NUCLEAR MEDICINE AND BIOLOGY

2004

New radioiodinated carboxylic and hydroxamic matrix metalloproteinase inhibitor tracers as potential tumor imaging agents

Ruth OltenfreiterLudovicus StaelensA LEJEUNEFilip DumontF FRANKENNEJM FOIDARTGuido Slegers

A1 Journal Article in NUCLEAR MEDICINE AND BIOLOGY

Synthesis and preliminary in vivo evaluation of [18F] labelled derivatives of Org 13063 as potential PET radioligands for the 5-HT1A receptor

MN VandecapelleFilip DumontPeter BlanckaertFilip De VosKarel StrijckmansDCM LeysenKurt AudenaertRudi DierckxGuido Slegers

2003

Decreased 5-HT2a receptor binding in patients with anorexia nervosa

Kurt AudenaertK VAN LAEREFilip DumontMyriam VervaetIngeborg GoethalsGuido SlegersJ MERTENSCornelis Van HeeringenRudi Dierckx

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Imaging of the 5-HT2A system: age-, gender-, and Alzheimer's disease-related findings

JAN VERSIJPTKJ VAN LAEREFilip DumontD DECOOMarleen VandecapellePatrick SantensIngeborg GoethalsKurt AudenaertGuido SlegersRudi Dierckx et al.

A1 Journal Article in NEUROBIOLOGY OF AGING

Prefrontal 5-HT2a receptor binding index, hopelessness and personality characteristics in attempted suicide

Cornelis Van HeeringenKurt AudenaertKoenraad Van LaereFilip DumontGuido SlegersJ MERTENSRudi Dierckx

A1 Journal Article in JOURNAL OF AFFECTIVE DISORDERS

Regional binding index of the radiolabeled selective 5-ht2a antagonist 123I-5-1-r91150 in the normal canine brain imaged with single photon emission computed tomography

Kathelijne PeremansKurt AudenaertFrank CoopmanFilip JacobsFilip DumontGuido SlegersFrancis VerschootenHenri van BreeJ MertensRudi Dierckx

A1 Journal Article in VETERINARY RADIOLOGY & ULTRASOUND

Synthesis and in vivo evaluation in mice and rabbits of [123I]-3-(4-iodobenzyl)-8-methoxy-1,2,3,4-tetrahydrochromeno[3,4-c]pyridin-5-one as possible agent for imaging of the dopamine D4-receptor

Ludovicus StaelensRuth OltenfreiterFilip DumontVeerle KersemansBart CornelissenGuido Slegers

Synthesis and in vivo evaluation of [123I]-pyrimidine-Org 13063 as potential SPECT radioligand for the 5-HT1A receptor

M VandecapelleFilip DumontRuth OltenfreiterKurt AudenaertD LeysenRudi DierckxGuido Slegers

Synthesis and radiolabelling of [I-123]-4-iodo-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-benzamide, a potential dopamine D-3 antagonist for SPECT studies

Ludovicus StaelensFilip DumontF DE VOSRuth OltenfreiterMarleen VandecapelleRudi DierckxGuido Slegers

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Synthesis and radiolabelling of [I-123]-4-iodo-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-benzamide, a potential dopamine D-3 antagonist for SPECT studies

Ludovicus StaelensFilip DumontF DE VOSRuth OltenfreiterMarleen VandecapelleRudi DierckxGuido Slegers

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

2002

An infected hip prosthesis in a dog diagnosed with a Tc-99m-ciprofloxacin (infecton) scan.

Kathelijne PeremansF DE WINTERL JANSSENSFilip DumontHenri van BreeRudi Dierckx

A1 Journal Article in VETERINARY RADIOLOGY & ULTRASOUND

Biodistribution and displacement studies of the selective 5-HT2A receptor antagonist I-123-5-I-R91150 in the normal dog.

Kathelijne PeremansKurt AudenaertFilip JacobsFilip DumontF DE VOSC VAN DE WIELEMarleen VandecapelleHenri van BreeFrancis VerschootenGuido Slegers et al.

A1 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

Synthesis and in vitro evaluation of N,N '-diphenyl and N-naphthyl-N '-phenylguanidines as N-methyl-D-aspartate receptor ion-channel ligands.

Filip DumontA SULTANARN WATERHOUSE

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and in vivo evaluation of [123I]-4-iodo-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-benzamide, a potential sigma receptor ligand for SPECT studies

Ludovicus StaelensFilip DumontFilip De VosRuth OltenfreiterIngeborg GoethalsRudi DierckxGuido Slegers

Synthesis of [C-11] N-(2-chloro-5-thiomethylphenyl)-N '-(3-methoxyphenyl)-N '-methylguanidine ([C-11]GMOM): a candidate PET tracer for imaging the PCP site of the NMDA ion channel.

RN WATERHOUSEFilip DumontA SULTANAN SIMPSONM LARUELLE

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

2001

Automated stereotactic standardization of brain SPECT receptor data using single-photon transmission images

Koenraad Van LaereMichel KooleYves D'AsselerJAN VERSIJPTKurt AudenaertFilip DumontRudi Dierckx

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Biodistribution and dosimetry of 99mTc-ciprofloxacin, a promising agent for the diagnosis of bacterial infection.

F DE WINTERC VAN DE WIELEFilip DumontJoost Van DurmeK SOLANKIK BRITTONG SLEGERS

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE

Decreased frontal serotonin 5-HT2a receptor binding index in deliberate self-harm patients.

Kurt AudenaertKoenraad Van LaereFilip DumontG SLEGERSJ MERTENSCornelis Van HeeringenRudi Dierckx

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE

In vivo evaluation of serotonin-2A receptors in normal canine brain: a SPECT study with a selective 5-HT2a receptor ligand labelled with 123I

Kathelijne PeremansKurt AudenaertP De BondtChristophe Van De WieleFilip DumontFilip JacobsGuido SlegersFrancis VerschootenHenri van BreeRudi Dierckx

Is there a role for agonist gastrin-releasing peptide receptor radioligands in tumour imaging?

C VAN DE WIELEFilip DumontSimon Van BelleG SLEGERSSH PEERSRudi Dierckx

A1 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

Le système serotoninergique dans le comportement suicidaire

Kurt AudenaertK Van LaereFilip DumontGuido SlegersCornelis Van HeeringenRudi Dierckx

A4 Journal Article in NEURONE (EDITION FRANCAISE)

Non-invasive methods for absolute cerebral blood flow measurement using 99m-Tc-ECD: A correlation study

KJ VAN LAEREMichel KooleFilip DumontJAN VERSIJPTG SLEGERSRudi Dierckx

Synthesis and Preliminary in vivo Evaluation of 4-[123I]iodo-N-{2-[4-(6-trifluoromethylpyridin- 2-yl)-piperazin-1-yl]ethyl}benzamide, a potential SPECT radioligand for the 5- HT1a receptor.

M VANDECAPELLEFilip De VosFilip DumontKurt AudenaertD LEIJSENRudi DierckxG SLEGERS

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Title: Synthesis, biodistribution and blocking studies in mice of a new 123I-labeled dopamine D3 antagonist Dierckx RA, Slegers G

Ludovicus StaelensFilip DumontF DEVOSRuth OltenfreiterM VANDECAPELLEIngeborg GoethalsRudi DierckxGuido Slegers

2000

Pharmacological evaluation of [C-11]conepezil as tracer for visualization of acetylcholinesterase by PET.

F DE VOSPatrick SantensHildegarde VermeirschI DEWOLFFilip DumontG SLEGERSRudi DierckxJacques De Reuck

A1 Journal Article in NUCLEAR MEDICINE AND BIOLOGY

Synthesis and in vitro stability of 123I-labelled annexin V: a potential agent for SPECT imaging of apoptotic cells.

C LAHORTEFilip DumontG SLEGERSC VAN DE WIELERudi DierckxJan Philippé

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Technetium-99m RP527, a GRP analogue for visualisation of GRP receptor-expressing malignancies: a feasibility study.

C VAN DE WIELEFilip DumontR VANDEN BROECKEW OOSTERLINCKVeronique CocquytRudolphe SerreynS PEERSJ THORNBACKG SLEGERSRudi Dierckx

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE

1999

Biodistribution and dosimetry of (iodine-123)-iodomethyl-N,N-diethyltamoxifen, an (anti)oestrogen receptor radioligand.

Christophe Van De WieleFilip De VosJohan De SutterFilip DumontG SLEGERSRudi DierckxHubert Thierens

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE

Effect of aromatic short-chain analogues of ceramide on axonal growth in hippocampal neurons.

Ilse Van OvermeireSA BOLDINFilip DumontSerge Van CalenberghG SLEGERSDenis De KeukeleireAH FUTERMANPiet Herdewijn

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

In vivo evaluation in mice and metabolism in blood of human volunteers of [I-123]iodo-PK11195: a possible single-photon emission tomography tracer for visualization of inflammation.

Filip DumontFilip De VosJAN VERSIJPTH JANSENJ KORFRudi DierckxG SLEGERS

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE

1998

Biodistribution and dehalogenation studies of two radiohalogenated kynurenic acid derivatives, potent antagonists of the N-methyl-D-aspartate receptor

Filip DumontGuido Slegers

1997

Radiolabelling optimisation of 7-bromo-5-[I-123]-iodo-4-oxo-1,4-dihydroquinoline-2-carboxylic acid: A potential tracer for NMDA SPECT studies.

Filip DumontGuido Slegers

A1 Journal Article in JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY

Synthesis and in vivo evaluation of 7-chloro-5-[I-123]iodo-4-oxo-1,4-dihydroquinoline-2-carboxylic acid.

Filip DumontGuido Slegers

A1 Journal Article in APPLIED RADIATION AND ISOTOPES

Synthesis of 7-chloro-5-123I-iodokynurenic acid:a possible tracer for in vivo imaging of N-methyl-D-aspartate receptors

Filip DumontGuido SlegersRudi Dierckx

A2 Journal Article in European Journal of Nuclear Medicine, nr. 24/8, pp.989

1996

Synthesis of [Br-77] 5,7-dibromo-4-oxo-1,4-dihydroquinoline-2-carboxylic acid, a possible SPECT tracer for NMDA receptor studies.

Filip DumontGuido Slegers

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

1995

SYNTHESIS OF 7-BROMO-5-IODO-4-OXO-1,4-DIHYDROQUINOLINE-2-CARBOXYLIC ACID.

Filip DumontGuido Slegers

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1993

Synthesis of (J^BT)5, 7-dibromo-4-oxo-l,4-dihydroquinoline-2-carboxylic acid for PET studies of N-methyl-D-aspartate receptors

Filip DumontGuido Slegers

A2 Journal Article in J. Nucl. Biol. Med., 1993, vol. 37, p. 167 & J. Pharm. Belg., vol. 48, p. 140