Research Explorer

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Researcher

Filip De Keyser

Publications & Research Data

Awards & Distinctions

376 Results

2022

Prevalence and management of drug interactions between nonsteroidal anti-inflammatory drugs and antithrombotics in ambulatory care

Els MehuysTine De BackerFilip De KeyserThierry ChristiaensThierry Van HeesSophie DemarcheInge Van TongelenKoen Boussery

A1 Journal Article in BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

2021

Incidence, prevalence and long-term progression of Goh algorithm rated interstitial lung disease in systemic sclerosis in two independent cohorts in flanders : a retrospective cohort study

Els VandecasteeleKarin MelsensAmber VanhaeckeDaniel BlockmansCarolien BonroyCharlotte CartonEllen DeschepperFilip De KeyserFrederic HoussiauYves Piette et al.

A1 Journal Article in SEMINARS IN ARTHRITIS AND RHEUMATISM

2020

Evaluation of the primary biliary cholangitis-related serologic profile in a large cohort of Belgian systemic sclerosis patients

LISA FLORINKaat RubbenAmber VanhaeckeKatrien DevreeseFilip De KeyserVanessa SmithCarolien Bonroy

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Pitfalls in the detection of myositis specific antibodies by lineblot in clinically suspected idiopathic inflammatory myopathy

Yves PietteMaxime De SloovereStien VandendriesscheJoke DehoorneJan De BleeckerLiesbet Van PraetAn-Sofie Vander MijnsbruggeSarah De SchepperPeggy JacquesFilip De Keyser et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

2019

Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases

Marialbert Acosta-HerreraMartin KerickDavid González-SernaCisca WijmengaAndre FrankePeter K GregersenLeonid PadyukovJane WorthingtonTimothy James VyseMarta Eugenia Alarcón-Riquelme et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Phenotypes determined by cluster analysis and their survival in the prospective European Scleroderma Trials and Research cohort of patients with systemic sclerosis

Vincent SobanskiJonathan GiovannelliYannick AllanoreGabriela RiemekastenSerena VettoriFranco CozziOliver DistlerMarco Matucci‐CerinicChristopher DentonDavid Launay et al.

A1 Journal Article in ARTHRITIS & RHEUMATOLOGY

Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis : a European Scleroderma Trials and Research (EUSTAR) analysis

Mike BeckerNicole GrafRafael SauterYannick AllanoreJohn CurramChristopher P DentonDinesh KhannaMarco Matucci-CerinicJanethe de Oliveira PenaJanet E Pope et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Progressive skin fibrosis is associated with a decline in lung function and worse survival in patients with diffuse cutaneous systemic sclerosis in the European Scleroderma Trials and Research (EUSTAR) cohort

Wanlong WuSuzana JordanNicole GrafJanethe de Oliveira PenaJohn CurramYannick AllanoreMarco Matucci-CerinicJanet E PopeChristopher P DentonDinesh Khanna et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

2018

A prospective, longitudinal study evaluating the baseline six-minute walk test as an individual reference value in systemic sclerosis patients

Els VandecasteeleKarin MelsensFilip De KeyserMichel De PauwEllen DeschepperSaskia DecumanYves PietteKristof ThevissenGuy BrusselleVanessa Smith

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Is laser speckle contrast analysis (LASCA) the new kid on the block in systemic sclerosis? : a systematic literature review and pilot study to evaluate reliability of LASCA to measure peripheral blood perfusion in scleroderma patients

Maurizio CutoloAmber VanhaeckeBarbara RuaroEllen DeschepperClaudia IckingerKarin MelsensYves PietteAmelia Chiara TrombettaFilip De KeyserVanessa Smith

A1 Journal Article in AUTOIMMUNITY REVIEWS

Nailfold capillaroscopy in systemic lupus erythematosus : a systematic review and critical appraisal

Maurizio CutoloKarin MelsensSara WijnantFrancesca IngegnoliKristof ThevissenFilip De KeyserSaskia DecumanUlf Müller-LadnerYves PietteValeria Riccieri et al.

A1 Journal Article in AUTOIMMUNITY REVIEWS

Reliability of simple capillaroscopic definitions in describing capillary morphology in rheumatic diseases

Maurizio CutoloKarin MelsensAriane L. HerrickIvan FoeldvariEllen DeschepperFilip De KeyserOliver DistlerFrancesca IngegnoliYora MostmansUlf Müller-Ladner et al.

A1 Journal Article in RHEUMATOLOGY

Two years follow-up of an open-label pilot study of treatment with rituximab in patients with early diffuse cutaneous systemic sclerosis

Karin MelsensEls VandecasteeleEllen DeschepperValérie BadotDaniel BlockmansGuy BrusselleEllen De LangheMichel De PauwClaire DebusschereSaskia Decuman et al.

A1 Journal Article in ACTA CLINICA BELGICA

2017

Nailfold capillaroscopy in systemic lupus erythematosus : a systematic review and critical appraisal

Sara WijnantF IngegnoliKarin MelsensKristof ThevissenFilip De KeyserSaskia DecumanEllen DeschepperG DistierU Mueller-LadnerYves Piette et al.

Prevalence and incidence of pulmonary arterial hypertension : 10-year follow-up of an unselected systemic sclerosis cohort

Els VandecasteeleKarin MelsensKristof ThevissenMichel De PauwEllen DeschepperSaskia DecumanYves PietteFilip De KeyserGuy BrusselleVanessa Smith

A2 Journal Article in JOURNAL OF SCLERODERMA AND RELATED DISORDERS

Role of the six-minute walk test in systemic sclerosis : five years evolution

Els VandecasteeleKarin MelsensFilip De KeyserMichel De PauwEllen DeschepperSaskia DecumanYves PietteKristof ThevissenGuy BrusselleVanessa Smith

Screening for pulmonary arterial hypertension in an unselected prospective systemic sclerosis cohort

Els VandecasteeleBENNY DRIEGHEKarin MelsensKristof ThevissenMichel De PauwEllen DeschepperSaskia DecumanCarolien BonroyYves PietteFilip De Keyser et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Six-minute walk test in or out in evaluation of systemic sclerosis patients?

Els VandecasteeleKristof ThevissenKarin MelsensFilip De KeyserMichel De PauwEllen DeschepperSaskia DecumanYves PietteGuy BrusselleVanessa Smith

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Systeemsclerose

Els VandecasteeleMichel De PauwEric DeromGuy BrusselleSofie De SchepperFilip De Keyser

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

The role of endothelial cells in the vasculopathy of systemic sclerosis : a systematic review

Y MostmansM CutoloC GiddeloSaskia DecumanKarin MelsensHeidi DeclercqEls VandecasteeleFilip De KeyserO DistlerJ Gutermuth et al.

A1 Journal Article in AUTOIMMUNITY REVIEWS

2016

An EULAR study group pilot study on reliability of simple capillaroscopic definitions to describe capillary morphology in rheumatic diseases

Vanessa SmithSam BeeckmanAriane L HerrickSaskia DecumanEllen DeschepperFilip De KeyserOliver DistlerIvan FoeldvariFrancesca IngegnoliUlf Müller-Ladner et al.

A1 Journal Article in RHEUMATOLOGY

Assessment of sensitivity to change of the European Scleroderma Study Group activity index

Karin MelsensFilip De KeyserSaskia DecumanGuy BrusselleMichel De PauwEllen DeschepperKatelijne De WildeDirk ElewautYVES PIETTEEls Vandecasteele et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Comparison of the Belgian Rheumatoid Arthritis Disability Assessment and Health Assessment questionnaires as tools to predict the need for support measures in patients with rheumatoid arthritis

Xavier JanssensSaskia DecumanFilip De Keyser

A1 Journal Article in PLOS ONE

Disease activity indices in systemic sclerosis : a systematic literature review

Karin MelsensFilip De KeyserSaskia DecumanYVES PIETTEEls VandecasteeleVanessa Smith

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Fuchs’ Uveitis syndrome : no longer a syndrome?

Elke O. KrepsTHIERRY DERVEAUXFilip De KeyserPhilippe Kestelyn

A1 Journal Article in OCULAR IMMUNOLOGY AND INFLAMMATION

Nailfold capillaroscopy and clinical applications in systemic sclerosis

Vanessa SmithKristof ThevissenAmelia C TrombettaCarmen PizzorniBarbara RuaroYVES PIETTESabrina PaolinoFilip De KeyserAlberto SulliKarin Melsens et al.

A1 Journal Article in MICROCIRCULATION

Reliability of the quantitative assessment of peripheral blood perfusion by laser speckle contrast analysis in a systemic sclerosis cohort

Valérie LambrechtMaurizio CutoloFilip De KeyserSaskia DecumanBarbara RuaroAlberto SulliEllen DeschepperVanessa Smith

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Screening for pulmonary arterial hypertension in an unselected prospective systemic sclerosis cohort : the DETECT algorithm vs. the 2009 European Society of Cardiology/European Respiratory Society guidellines on pulmonary hypertension

Els VandecasteeleBENNY DRIEGHEKarin MelsensKristof ThevissenMichel De PauwEllen DeschepperSaskia DecumanFilip De KeyserCarolien BonroyYves Piette et al.

Six-minute walk test in systemic sclerosis : a systematic review and meta-analysis

Els VandecasteeleMichel De PauwFilip De KeyserSaskia DecumanEllen DeschepperYVES PIETTEGuy BrusselleVanessa Smith

A1 Journal Article in INTERNATIONAL JOURNAL OF CARDIOLOGY

Six-minute walk test in systemic sclerosis patients

Els VandecasteeleKarin MelsensFilip De KeyserMichel De PauwEllen DeschepperSaskia DecumanYVES PIETTEGuy BrusselleVanessa Smith

Six-minute walk test in systemic sclerosis patients without interstitial lung disease and pulmonary arterial hypertension

Els VandecasteeleKarin MelsensFilip De KeyserMichel De PauwEllen DeschepperSaskia DecumanYVES PIETTEGuy BrusselleVanessa Smith

Specific antinuclear antibody level changes after B cell depletion therapy in systemic sclerosis are associated with improvement of skin thickening

Carolien BonroyVanessa SmithEllen DeschepperFilip De KeyserKatrien Devreese

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Stabilization of microcirculation in patients with early systemic sclerosis with diffuse skin involvement following rituximab treatment: an open-label study

Vanessa SmithCarmen PizzorniValeria RiccieriSaskia DecumanGuy BrusselleMichel De PauwEllen DeschepperYVES PIETTEBarbara RuaroAlberto Sulli et al.

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

The heart and pulmonary arterial hypertension in systemic sclerosis

Els VandecasteeleMichel De PauwGuy BrusselleSaskia DecumanYves PietteFilip De KeyserVanessa Smith

A1 Journal Article in ACTA CLINICA BELGICA

2015

An EULAR Study Group pilot study on reliability of simple capillaroscopic definitions to describe capillary morphology in rheumatic diseases

Vanessa SmithSam BeeckmanAriane L HerrickSaskia DecumanEllen DeschepperFilip De KeyserOliver DistlerIvan FoeldvariFrancesca IngegnoliUlf Müller-Ladner et al.

Evaluatie van activiteitenbeperkingen bij personen met reumatoïde artritis in het kader van de bestaande wettelijke referentiekaders in België

Xavier JanssensFilip De Keyser

Factors influencing the occupational trajectory of patients with systemic sclerosis: a qualitative study

Saskia DecumanVanessa SmithMaria GrypdonckFilip De KeyserSofie Verhaeghe

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Lupus anticoagulant-hypoprothrombinemia syndrome: report of two cases and review of the literature

SYLVIE MULLIEZFilip De KeyserCAROLINE VERBISTANNA VANTILBORGHW WijnsI BeukingaKatrien Devreese

A1 Journal Article in LUPUS

Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database

Britta MaurerNicole GrafBeat A MichelUlf Müller-LadnerLászló CzirjákChristopher P DentonAlan TyndallCarola MetzigVivian LaniusDinesh Khanna et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Reliability of the quantitative assessment of peripheral blood perfusion by laser speckle contrast analysis in a systemic sclerosis cohort

Valérie LambrechtMaurizio CutoloFilip De KeyserSaskia DecumanBarbara RuaroAlberto SulliEllen DeschepperVanessa Smith

Six-minute walk test in systemic sclerosis : systematic review and meta-analysis

Els VandecasteeleMichel De PauwFilip De KeyserSaskia DecumanEllen DeschepperYVES PIETTEGuy BrusselleVanessa Smith

Update on antinuclear antibodies in systemic sclerosis

Carolien BonroyFilip De KeyserKatrien Devreese

2014

Arbeidsparticipatie van mensen met systeemsclerose

Saskia DecumanFilip De KeyserSofie Verhaeghe

Assessment of activity limitations with the Health Assessment Questionnaire predicts the need for support measures in patients with rheumatoid arthritis : a multicenter observational study

Xavier JanssensSaskia DecumanFilip De Keyser

A1 Journal Article in PLOS ONE

Growth differentiation factor 15, a marker of lung involvement in systemic sclerosis, is involved in fibrosis development but is not indispensable for fibrosis development

Stijn LambrechtVanessa SmithKatelijne De WildeJulie CoudenysSaskia DecumanDieter DeforceFilip De KeyserDirk Elewaut

A1 Journal Article in ARTHRITIS & RHEUMATOLOGY

Longterm followup of rituximab therapy in patients with rheumatoid arthritis: results from the Belgian MabThera in Rheumatoid Arthritis registry

Filip De KeyserIlse HoffmanPatrick DurezMarie-Joëlle KaiserR Westhovens

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis

L van BonAJ AffandiJ BroenRB ChristmannRJ MarijnissenL StawskiGA FarinaG StifanoAL MathesM Cossu et al.

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

Relevance of different results of different anti-double-stranded DNA assays in reporting clinical studies : comment on the article by Petri et al

Carolien BonroyCharlotte VerfaillieEvy De WitteFilip De Keyser

A1 Journal Article in ARTHRITIS & RHEUMATOLOGY

Ten-year followup of infliximab therapy in rheumatoid arthritis patients with severe, longstanding refractory disease: a cohort study

Filip De KeyserJORIS DE KOCKHermine LeroiPatrick DurezRené Westhovens

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Tuberculin skin test versus interferon-gamma release assays for the diagnosis of tuberculosis infection

Eline De KeyserFilip De KeyserFrans De Baets

A1 Journal Article in ACTA CLINICA BELGICA

Work participation in patients with systemic sclerosis: a systematic review

Saskia DecumanVanessa SmithSofie VerhaegheAnn Van HeckeFilip De Keyser

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

2013

Automated indirect immunofluorescence antinuclear antibody analysis is a standardized alternative for visual microscope interpretation

Carolien BonroyCharlotte VerfaillieVanessa SmithLies PersijnEvy De WitteFilip De KeyserKatrien Devreese

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Cancer risk in immune-mediated inflammatory diseases (IMID)

Rudi BeyaertLaurent BeaugerieGert Van AsscheLieve BrochezJean-Christophe RenauldManuelle ViguierVeronique CocquytGuy JerusalemJean-Pascal MachielsHans Prenen et al.

A1 Journal Article in MOLECULAR CANCER

Construction and psychometric properties of the Belgian Rheumatoid Arthritis Disability Assessment (BRADA) questionnaire : a new tool for the evaluation of activity limitations in patients with rheumatoid arthritis

Xavier JanssensSaskia DecumanFilip De Keyser

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Nailfold capillaroscopy for prediction of novel future severe organ involvement in systemic sclerosis

Vanessa SmithValeria RiccieriCarmen PizzorniSaskia DecumanEllen DeschepperCarolien BonroyAlberto SulliYves PietteFilip De KeyserMaurizio Cutolo

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Optimal approaches to data collection and analysis of potential immune mediated disorders in clinical trials of new vaccines

Fernanda Tavares Da SilvaFilip De KeyserPaul-Henri LambertWilliam H RobinsonRené WesthovensChristian Sindic

A1 Journal Article in VACCINE

Oral administration of GLPG0259, an inhibitor of MAPKAPK5, a new target for the treatment of rheumatoid arthritis: a phase II, randomised, double-blind, placebo-controlled, multicentre trial

René WesthovensFilip De KeyserDmytro RekalovEvgeny L NasonovJohan BeetensAnnegret Van der AaPiet WigerinckFlorence NamourFrédéric VanhouttePatrick Durez

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Quantification of IFNγ- and IL17-producing cells after stimulation with citrullinated proteins in healthy subjects and RA patients

Katleen Van SteendamMarlies De CeuleneerKelly TillemanDirk ElewautFilip De KeyserDieter Deforce

A1 Journal Article in RHEUMATOLOGY INTERNATIONAL

The influence of ageing on the development and management of rheumatoid arthritis

Annemieke MH BootsAndrea B MaierPiet StinissenPierre MassonRik J LoriesFilip De Keyser

A1 Journal Article in NATURE REVIEWS RHEUMATOLOGY

The integration of the detection of systemic sclerosis-associated antibodies in a routine laboratory setting: comparison of different strategies

Carolien BonroyVanessa SmithKatleen Van SteendamJens Van PraetDieter DeforceKatrien DevreeseFilip De Keyser

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Two-year results of an open pilot study of a 2-treatment course with rituximab in patients with early systemic sclerosis with diffuse skin involvement

Vanessa SmithYVES PIETTEJens Van PraetSaskia DecumanEllen DeschepperDirk ElewautFilip De Keyser

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

2012

Do worsening scleroderma capillaroscopic patterns predict future severe organ involvement? : a pilot study

Vanessa SmithSaskia DecumanAlberto SulliCarolien BonroyYves PietteEllen DeschepperFilip De KeyserMaurizio Cutolo

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Fluoroenzymeimmunoassay to detect systemic sclerosis-associated antibodies : diagnostic performance and correlation with conventional techniques

Carolien BonroyVanessa SmithKatleen Van SteendamJens Van PraetDieter DeforceKatrien DevreeseFilip De Keyser

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Management of inflammatory bowel disease in pregnancy

Séverine VermeireFranck CarbonnelPierre G CoulieVincent GeenenJohanna MW HazesPierre L MassonFilip De KeyserEdouard Louis

A1 Journal Article in JOURNAL OF CROHNS & COLITIS

Optimization and diagnostic performance of a single multiparameter lineblot in the serological workup of systemic sclerosis

Carolien BonroyJens Van PraetVanessa SmithKatleen Van SteendamT MimoriEllen DeschepperDieter DeforceKatrien DevreeseFilip De Keyser

A1 Journal Article in JOURNAL OF IMMUNOLOGICAL METHODS

The autoimmune disease-associated IL2RA locus is involved in the clinical manifestations of systemic sclerosis

Jose-Ezequiel MartinF David CarmonaJasper CA BroenCarmen P SimeonMadelon C VonkPatricia CarreiraRaquel Ríos-FernándezGerard EspinosaEsther Vicente-RabanedaCarlos Tolosa et al.

A1 Journal Article in GENES AND IMMUNITY

The Belgian Systemic Sclerosis Cohort: correlations between disease severity scores, cutaneous subsets, and autoantibody profile

Marie VanthuyneVanessa SmithEllen De LangheJens Van PraetSeher AratGeneviève DepresseuxRene WesthovensDaniel BlockmansValérie BadotElie Cogan et al.

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Three-year follow-up of rituximab in rheumatoid arthritis: results from the Belgian MIRA (MabThera in Rheumatoid Arthritis) registry

Filip De KeyserPatrick DurezRené WesthovensMarie-Joëlle KaiserIlse Hoffman

Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database

Florian MP MeierKlaus W FrommerRobert DinserUlrich A WalkerLaszlo CzirjakChristopher P DentonYannick AllanoreOliver DistlerGabriela RiemekastenGabriele Valentini et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Work participation and work transition in patients with systemic sclerosis: a cross-sectional study

Saskia DecumanVanessa SmithSofie VerhaegheEllen DeschepperFrans VermeirenFilip De Keyser

A1 Journal Article in RHEUMATOLOGY

2011

A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort

Lara Bossini-CastilloJasper CA BroenCarmen P SimeonLorenzo BerettaMadelon C VonkNorberto Ortego-CentenoGerard EspinosaPatricia CarreiraMaría Teresa CampsNuria Navarette et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

A twelve-week exploratory phase II trial of GLPG0259 versus placebo in patients with active rheumatoid arthritis and inadequate response to methotrexate

Rene WesthovensFilip De KeyserDmitro RekalovEvgeny L NasonovJohan BeetensAnnegret Van der AaPiet WigerinckFlorence NamourFrederic VanhouttePatrick Durez

Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis

L Diaz-GalloP GourhJ BroenC SimeonV FonollosaN Ortego-CentenoS AgarwalMC VonkM CoenenG Riemekasten et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Dysregulated adaptive immunity in two models of immune mediated inflammatory diseases: rheumatoid arthritis and systemic sclerosis

Katleen Van SteendamDieter DeforceFilip De KeyserDirk Elewaut

GDF15, a distinct TGFb family member, is differentially regulated in spondyloarthritides compared to other rheumatic diseases

Stijn LambrechtJulie CoudenysFilip De KeyserAugust VerbruggenDieter DeforceDirk Elewaut

Hand radiological damage in systemic sclerosis: comparison with a control group and clinical and functional correlations

Sophie KoutaissoffMarie VanthuyneVanessa SmithEllen De LangheGenevieve DepresseuxRene WesthovensFilip De KeyserJacques MalghemFrédéric A Houssiau

A1 Journal Article in SEMINARS IN ARTHRITIS AND RHEUMATISM

Histopathological cutaneous alterations in systemic sclerosis : a clinicopathological study

Jens Van PraetVanessa SmithMarc HaspeslaghNele DegryseDirk ElewautFilip De Keyser

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy

Olga GorlovaJose-Ezequiel MartinBlanca RuedaBobby PC KoelemanJun YingMaria TeruelLina-Marcela Diaz-GalloJasper C BroenMadelon C VonkCarmen P Simeon et al.

A1 Journal Article in PLOS GENETICS

Is there a role for TNF-α antagonists in the treatment of SSc?: EUSTAR expert consensus development using the Delphi technique

JHW DistlerS JordanP AiròJJ Alegre-SanchoY AllanoreAB GurmanR CaporaliP CaramaschiPE CarreiraC Chizzolini et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Microscopic polyangiitis involving the breast

MIEKE DEVINCKBert Vander CruyssenKathleen LambeinFilip De KeyserMarleen PraetGuy Brusselle

A1 Journal Article in ACTA CLINICA BELGICA

Nailfold capillaroscopy for day-to-day clinical use: construction of a simple scoring modality as a clinical prognostic index for digital trophic lesions

Vanessa SmithFilip De KeyserCarmen PizzorniJens Van PraetSaskia DecumanAlberto SulliEllen DeschepperMaurizio Cutolo

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Novel autoantibody markers for early and seronegative rheumatoid arthritis

Klaartje SomersPiet GeusensDirk ElewautFilip De KeyserJean-Luc RummensMarieke CoenenMarlies BlomPiet StinissenVeerle Somers

A1 Journal Article in JOURNAL OF AUTOIMMUNITY

Reduced levels of the TGFB family member GDF15 in spondyloarthritis versus other rheumatic diseases

Stijn LambrechtJulie CoudenysFilip De KeyserAugust VerbruggenDieter DeforceDirk Elewaut

Rheumatoid arthritis and pregnancy: evolution of disease activity and pathophysiological considerations for drug use

Johanna MW HazesPierre G CoulieVincent GeenenSeverine VermeireFranck CarbonnelEdouard LouisPierre MassonFilip De Keyser

A1 Journal Article in RHEUMATOLOGY

Specific anti-nuclear antibodies in systemic sclerosis patients with and without skin involvement : an extended methodological approach

Jens Van PraetKatleen Van SteendamVanessa SmithGeorges De BruyneTsuneyo MimoriCarolien BonroyDirk ElewautDieter DeforceFilip De Keyser

A1 Journal Article in RHEUMATOLOGY

Two years follow-up results after rituximab treatment (baseline and month 6) in patients with 'early' systemic sclerosis with diffuse skin involvement

Vanessa SmithYVES PIETTESaskia DecumanJens Van PraetEllen De SchepperFilip De Keyser

2010

74-week follow-up of safety of infliximab in patients with refractory rheumatoid arthritis

Isabelle DelabayeFilip De Keyser

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins

Katleen Van SteendamKelly TillemanMarlies De CeuleneerFilip De KeyserDirk ElewautDieter Deforce

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

Timothy RDJ RadstakeOlga GorlovaBlanca RuedaJose-Ezequiel MartinBehrooz Z AlizadehRogelio Palomino-MoralesMarieke J CoenenMadelon C VonkAlexandre E VoskuylAnnemie J Schuerwegh et al.

A1 Journal Article in NATURE GENETICS

Hand radiological damage in systemic sclerosis: clinical and functional correlations

M VanthuyneJ MalghemVanessa SmithS AratE DelangheG DepresseuxFilip De KeyserR WesthovensFA HoussiauS Koutaissof

Intranasal administration of recombinant human cartilage glycoprotein-39 as a treatment for rheumatoid arthritis: a phase II, multicentre, double-blind, randomised, placebo-controlled, parallel-group, dose-finding trial

Robert BM LandewéJos GA HoubiersFilip Van den BoschJoanna in't HoutPatrick CPM VerschuerenJan H MeijerinkFrank HJ van den HoogenBedrich A MasekGeorge AW BruynJacques MGW Wouters et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Preventie en behandeling van A/H1N1-influenza bij patiënten met immuungemedieerde inflammatoire aandoeningen onder immunotherapie

Filip De KeyserMichel De La BrassinneJo LambertB LauwerysE LouisG Van AsscheA Van GompelR WesthovensMarc Van Ranst

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Reduced levels of the TGFB family member GDF15 in spondyloarthritis versus other rheumatic diseases

Stijn LambrechtFilip Van den BoschBert Vander CruyssenFilip De KeyserAugust VerbruggenDieter DeforceDirk Elewaut

Reliability of the qualitative and semiquantitative nailfold videocapillaroscopy assessment in a systemic sclerosis cohort : a two-centre study

Vanessa SmithCarmen PizzorniFilip De KeyserSaskia DecumanJens Van PraetEllen DeschepperAlberto SulliMaurizio Cutolo

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Reliability of the qualitative and semiquantitative nailfold videocapillaroscopy assessment in a systemic sclerosis cohort: a bi-centre study

Vanessa SmithC PizzorniFilip De KeyserSaskia DecumanJens Van PraetE De SchepperA SulliM Cutolo

Rituximab in diffuse cutaneous systemic sclerosis: an open-label clinical and histopathological study

Vanessa SmithJens Van PraetBERNARD VANDOORENBert Van der CruyssenJ.-M. NaeyaertSaskia DecumanDirk ElewautFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Seven-year follow-up of infliximab therapy in rheumatoid arthritis patients with severe long-standing refractory disease : attrition rate and evolution of disease activity

Bert Vander CruyssenPatrick DurezRene WesthovensFilip De Keyser

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis

Lode MelisBERNARD VANDOORENElli KruithofPeggy JacquesMartine De VosHerman MielantsAugust VerbruggenFilip De KeyserDirk Elewaut

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

The Belgian MIRA (MabThera In Rheumatoid Arthritis) registry: clues for the optimization of rituximab treatment strategies

Bert Vander CruyssenPatrick DurezRene WesthovensMarie-Joelle KaiserIlse HoffmanFilip De Keyser

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Vaccinations in patients with immune-mediated inflammatory diseases

Jean-François RahierMichel MoutschenAlfons Van GompelMarc Van RanstEdouard LouisSiegfried SegaertPierre MassonFilip De Keyser

A1 Journal Article in RHEUMATOLOGY

2009

Citrullination breaks T-cell tolerance in patients with inflammatory arthritides and in healthy persons

Katleen Van SteendamMarlies De CeuleneerFilip De KeyserDirk ElewautKelly TillemanDieter Deforce

Classification models for disease: the effect of associations between markers on calculating the risk for disease by likelihood ratio products

Ruth WittoekFilip De KeyserA BoonenKurt de VlamNathan VastesaegerHerman MielantsBert Vander Cruyssen

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Clinical Observations programme in SpA: disease parameters, treatment options and practical management issues

Dirk ElewautFilip Van den BoschAugust VerbruggenFilip De KeyserBert Vander CruyssenHerman Mielants

A1 Journal Article in Rheumatology International

Juvenile-onset systemic lupus erythematosus: different clinical and serological pattern than adult-onset systemic lupus erythematosus

IEA HoffmanBR LauwerysFilip De KeyserTWJ HuizingaD IsenbergL CebecauerJoke DehoorneRik JoosG HendrickxF Houssiau et al.

A1 Journal Article in Annals of the Rheumatic Diseases

Melanoma inhibitory activity, a biomarker related to chondrocyte anabolism, is reversibly suppressed by proinflammatory cytokines in rheumatoid arthritis

BERNARD VANDOORENTineke CantaertMJ van LieropE BosLeen De RyckeEric VeysFilip De KeyserB BresnihanFrank LuytenPeter Verdonk et al.

A1 Journal Article in Annals of the Rheumatic Diseases

Reversible changes in serum immunoglobulin galactosylation during the immune response and treatment of inflammatory autoimmune arthritis

Katrien Van BenedenKen CoppietersW LaroyFilip De KeyserIlse HoffmanFilip Van den BoschBert Vander CruyssenMichael DrennanPeggy JacquesP Rottiers et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis

Lode MelisBERNARD VANDOORENElli KruithofPeggy JacquesMartine De VosHerman MielantsAugust VerbruggenFilip De KeyserDirk Elewaut

T cell reactivity against citrullinated proteins does not differ between healthy persons and patients with inflammatory arthritis

Katleen Van SteendamMarlies De CeuleneerFilip De KeyserDirk ElewautKelly TillemanDieter Deforce

Validation of a manual ability questionnaire in patients with systemic sclerosis

Marie VanthuyneVanessa SmithSeher AratRene WesthovensFilip De KeyserFrederic HoussiauJean-Louis ThonnardLaure Vandervelde

A1 Journal Article in ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH

Validation of a new screening strategy for anti-extractable nuclear antigen antibodies

Jens Van PraetBert Vander CruyssenCarolien BonroyVanessa SmithJoris DelangheFilip De Keyser

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

2008

Do all anti-citrullinated protein/peptide antibody tests measure the same? Evaluation of discrepancy between anti-citrullinated protein/peptide antibody tests in patients with and without rheumatoid arthritis

Bert Vander CruyssenL NOGUEIRAJens Van PraetDieter DeforceDirk ElewautG SERREFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Identification and possible citrullination of antigens in immune complexes in patients with rheumatoid arthritis

Katleen Van SteendamKelly TillemanMarlies De CeuleneerMaarten DhaenensDirk ElewautFilip De KeyserDieter Deforce

Local and systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis

BERNARD VANDOORENLode MelisElli KruithofPeggy JacquesMartine De VosHerman MielantsAugust VerbruggenFilip De KeyserDirk Elewaut

Over-representation of construction-related occupations in male patients with systemic sclerosis

Vanessa SmithM. VanthuyneBert Vander CruyssenJens Van PraetF. VermeirenH. SmetsF. HoussiauFilip De Keyser

A1 Journal Article in Annals of the Rheumatic Diseases

Prediction models for disease: The effect of associations between markers on calculating the risk for disease by likelihood ratio products in SpA

Bert Vander CruyssenRuth WittoekA BOONENKurt De VlamN VASTESAEGERW NOELHerman MielantsFilip De Keyser

Reduced metallothionein expression in colonic Crohn's disease: evidence for a new disease-modifying gene

Debby LaukensHarald PeetersAnouk WaeytensSara BogaertBert Vander CruyssenDirk ElewautFilip De KeyserHerman MielantsClaude CuvelierKenny Knecht et al.

Reduced metallothionein expression in colonic Crohn's disease: evidence for it new disease-modifying gene

Debby LaukensHarald PeetersAnouk WaeytensSara BogaertBert Vander CruyssenDirk ElewautFilip De KeyserHerman MielantsClaude CuvelierP Van Hummelen et al.

Spontaneous amelioration in early RA: Role of antibody profiles in predicting decrease of disease activity

Bert Vander CruyssenAMM MILTENBURGFilip Van den BoschJ HOUBIERSRuth WittoekAMH BOOTSFilip De Keyser

Synovial detection and autoantibody reactivity of processed citrullinated isoforms of vimentin in inflammatory arthritides

Kelly TillemanKatleen Van SteendamTineke CantaertFilip De KeyserDirk ElewautDieter Deforce

A1 Journal Article in RHEUMATOLOGY

Tapering infliximab dosages after temporary dose increase does not affect treatment survival in an established RA population

Bert Vander CruyssenR WESTHOVENSP DUREZFilip Van den BoschHerman MielantsL DE CLERCKA PERETZM MALAISEL VERBRUGGENL DEWULF et al.

Validation of a new screening strategy for anti-ENA antibodies

Jens Van PraetBert Vander CruyssenCarolien BonroyVanessa SmithJoris DelangheFilip De Keyser

2007

A prospective randomised multicentre study comparing continuous and intermittent treatment with celecoxib in patients with osteoarthritis of the knee or hip

FP LUYTENP GEUSENSM MALAISEL DE CLERCKR WESTHOVENSF RAEMAND VANDER MIJNSBRUGGEL MATHYJP HAUZEURFilip De Keyser et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Anti-TNF-therapie bij patiënten met chronische artritis

Jens Van PraetPhilippe Winnock De GraveFilip De Keyser

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Anti-TNFalpha induced apoptosis contributes to the induction of autoantibodies but not the decrease of synovial inflammation in spondyloarthropathy (SpA)

LEEN DE RYCKETineke CantaertBERNARD VANDOORENElli KruithofCA WIJBRANDTSFilip De KeyserEric VeysPP TAKDominique Baeten

CARD15 variants determine a disturbed early response of monocytes to adherent-invasive Escherichia coli strain LF82 in Crohn's disease

Harald PeetersSara BogaertDebby LaukensPieter RottiersFilip De KeyserA Darfeuille-MichaudAL GlasserDirk ElewautMartine De Vos

A1 Journal Article in INTERNATIONAL JOURNAL OF IMMUNOGENETICS

Comparison of different outcome measures for psoriatic arthritis in patients treated with infliximab or placebo

BERT VANDER CRUYSSENFilip De KeyserELLI KRUITHOFHerman MielantsFilip Van den Bosch

Editorial material

Decrease of disease activity under ineffective therapy in DMARD-naive patients with early rheumatoid arthritis: Role of antibody profiles and carriage of the HLA shared epitope in predicting decrease of disease activity

BERT VANDER CRUYSSENAMM MILTENBURGFilip Van den BoschJGA HOUBIERSRuth WittoekAMH BOOTSFilip De Keyser

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Effects of intra-articular corticosteroids and anti-TNF therapy on neutrophil activation in rheumatoid arthritis

H WITTKOWSKID FOELLE AF KLINTLEEN DE RYCKEFilip De KeyserM FROSCHAK ULFGRENJ ROTH

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Endogenous HLA-DR-restricted presentation of the cartilage antigens human cartilage gp-39 and melanoma inhibitory activity in the inflamed rheumatoid joint

MJC VAN LIEROPL DEN HOEDJ HOUBIERSJ VENCOVSKYS RUZICKOVAO KRYSTUFKOVAM VAN SCHAARDENBURGF VAN DEN HOOGENBERNARD VANDOORENDominique Baeten et al.

A1 Journal Article in ARTHRITIS AND RHEUMATISM

In pursuit of B-cell synovial autoantigens in rheumatoid arthritis: Confirmation of citrullinated fibrinogen, detection of vimentin, and introducing carbonic anhydrase as a possible new synovial autoantigen

Kelly TillemanAnn UnionT CANTAERTS DE KEYSERA DANIELSDirk ElewautFilip De KeyserDieter Deforce

A1 Journal Article in PROTEOMICS CLINICAL APPLICATIONS

Non-pathogenic antinuclear antibodies contribute to the clearance of apoptotic antigens released during TNF alpha blockade in spondyloarthritis (SpA)

Tineke CantaertLEEN DE RYCKEBERNARD VANDOORENC WIJBRANDTSElli KruithofFilip De KeyserEric VeysPP TAKDominique Baeten

Polymorphisms in the ficolin 1 gene (FCN1) are associated with susceptibility to the development of rheumatoid arthritis

Bert Vander CruyssenLieve NuytinckLuc BoullartDirk ElewautWillem WaegemanMira Van ThielenE. DE MEESTERK. LEBEERR. ROSSAUFilip De Keyser

A1 Journal Article in RHEUMATOLOGY

Polymorphisms in the ficolin 1 gene (FCN1) are associated with susceptibility to the development of rheumatoid arthritis and may have an added value in prediction models

Bert Vander CruyssenLieve NuytinckFilip De Keyser

Prediction models for rheumatoid arthritis during diagnostic investigation: evaluation of combinations of rheumatoid factor, anti-citrullinated protein/peptide antibodies and the human leucocyte antigen-shared epitope

BERT VANDER CRUYSSENIlse HoffmanIsabelle PeeneAnn UnionHerman MielantsL MEHEUSFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Re: Pulmonary arterial hypertension in connective tissue diseases

Vanessa SmithMichel De PauwGuy BrusselleJens Van PraetFilip De Keyser

A1 Journal Article in RHEUMATOLOGY

Specifieke antinucleaire antilichamen bij patiënten met systeemsclerose

Jens Van PraetVanessa SmithFilip De Keyser

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Spondyloarthropathies

Filip De Keyser

Editorial material

2006

Accuracy of anti-ribosomal P protein antibody testing for the diagnosis of neuropsychiatric systemic lupus erythematosus - An international meta-analysis

FB KARASSAA AFELTRAA AMBROZICDM CHANGFilip De KeyserA DORIAM GALEAZZIS HIROHATAIlse HoffmanM INANC et al.

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Altered gut transcriptome in spondyloarthropathy

Debby LaukensHarald PeetersBert Vander CruyssenTom BoonefaesDirk ElewautFilip De KeyserHerman MielantsClaude CuvelierEric VeysKenny Knecht et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Alternative method to identify susceptibility genes for Crohn's disease through transcriptome analysis

D LAUKERSH PECTERSFilip De KeyserEric VeysClaude CuvelierDirk ElewautErik RemautMartine De VosP ROTTIERS

Anti-TNF alpha induced apoptosis contributes to the induction of Autoantibodies but not the decrease of synovial inflammation in spondyloarthropathy (SPA)

Tineke CantaertLEEN DE RYCKEBERNARD VANDOORENELLI KRUITHOFFilip De KeyserEric VeysDominique Baeten

Anti-TNF-alpha therapy in ankylosing spondylitis

Filip De KeyserFilip Van den BoschHerman Mielants

A1 Journal Article in CYTOKINE

Anti-TNFalpha induced apoptosis contributes to the induction of autoantibodies but not the decrease of synovial inflammation in spondyloarthropathy

Tineke CantaertLEEN DE RYCKEBERNARD VANDOORENELLI KRUITHOFC WIJBRANDTSFilip De KeyserEric VeysPP TAKDominique Baeten

Comparison of the anti-human citrullinated fibrinogen antibodies assayed by ELISA with 2 other ACPA assays: Diagnostic value and agreement between assays

Bert Vander CruyssenL NOGUEIRATineke CantaertC CAVELLEEN DE RYCKEM SEBAGDieter DeforceDirk ElewautG SERREFilip De Keyser

Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays

Bert Vander CruyssenTineke CantaertL NOGUEIRAC CLAVELLEEN DE RYCKEA DENDOVENM SEBAGDieter DeforceC VINCENTDirk Elewaut et al.

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Effect of age on prevalence of anticitrullinated protein/peptide antibodies in polyarticular juvenile idiopathic arthritis

Pieter DewintIlse HoffmanS ROGGER JOOSAnn UnionJ DEHOORNEJ DELANGHEEric VeysFilip De KeyserDirk Elewaut

A1 Journal Article in RHEUMATOLOGY

Four year follow-up of infliximab in rheumatoid arthritis patients refractory to multiple dmard treatment: Long-term clinical effect and prediction of attrition

Bert Vander CruyssenR WESTHOVENSP DUREZFilip Van den BoschHerman MielantsL DE CLERCKA PERETZM MALAISEL VERBRUGGENN VASTESAEGER et al.

Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity

Bert Vander CruyssenStijn Van LooyBart WynsR WESTHOVENSP DUREZFilip Van den BoschHerman MielantsL DE CLERCKA PERETZM MALAISE et al.

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Growth promoting effect of human cartilage glycoprotein-39 (HC gp-39) on synovial fibroblasts

BERNARD VANDOORENG VERHEIJDENTineke CantaertE BOSEric VeysFilip De KeyserA BOOTSDominique Baeten

Identification of synovial biomarkers of response to experimental treatment in early-phase clinical trials in spondylarthritis

ELLI KRUITHOFLEEN DE RYCKEBERNARD VANDOORENFilip De KeyserO FITZGERALDI MCINNESPP TAKB BRESNIHANEric VeysDominique Baeten

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Identification of synovial biomarkers of response to treatment in spondyloarthropathy

BERNARD VANDOORENELLI KRUITHOFLEEN DE RYCKEFilip De KeyserO FITZGERALDL MCINNESP TAKB BRESNIHANEric Veys

Leflunomide and methotrexate combination therapy in daily clinical practice

A DendoovenLEEN DE RYCKEXavier VerhelstHerman MielantsEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Mannose-binding lectin (MBL2) polymorphisms in rheumatoid arthritis (RA) are not associated with susceptibility or radiological progression rate

LEEN DE RYCKEIsabelle PeeneELLI KRUITHOFT Van De CasteeleL NuytinckEric VeysFilip De Keyser

Polymorphisms in the ficolin 1 gene (Fcn1) are associated with susceptibility to the development of rheumatoid arthritis

Bert Vander CruyssenLieve NuytinckFilip De Keyser

Prediction of dose escalation for rheumatoid arthritis patients under infliximab treatment

Stijn Van LooyBert Vander CruyssenJeroen MeeusBart WynsR WESTHOVENSP DUREZFilip Van den BoschN VASTESAEGERA GELDHOFLuc Boullart et al.

A1 Journal Article in ENGINEERING APPLICATIONS OF ARTIFICIAL INTELLIGENCE

Spondyloarthropathies

Filip De Keyser

Editorial material

Synovial inflammation does not change in the absence of effective treatment: implications for the use of synovial histopathology as biomarker in early phase clinical trials in rheumatoid arthritis

Dominique BaetenJ HOUBIERSELLI KRUITHOFBERNARD VANDOORENFilip Van den BoschAM BOOTSEric VeysAMM MILTENBURGFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

The diagnostic value of the anti-human citrullinated fibrinogen antibodies by elisa compared to anti-CCP2 antibodies, and their agreement with ACPA detected by 3 other substrates

Bert Vander CruyssenL NogueiraT CantaertC CavelLies De RyckeM SebagDieter DeforceDirk ElewautG SerreFilip De Keyser

2005

5-year safety and efficacy follow-up in 107 spondyloarthropathy patients with continued long-term infliximab treatment

Filip Van den BoschMIEKE DEVINCKElli KruithofG VERBRUGGENFilip De KeyserHerman MielantsEric Veys

Anti-citrullinated peptide antibodies may occur in patients with psoriatic arthritis

Bert Vander CruyssenIlse HoffmanHans-Georg ZmierczakMarthe Van Den BergheElli KruithofLeen De RyckeHerman MielantsEric VeysDominique BaetenFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Anti-citrullinated protein/peptide antibodies (ACPA) in rheumatoid arthritis: Specificity and relation with rheumatoid factor

Bert Vander CruyssenIsabelle PeeneTineke CantaertIlse HoffmanLeen De RyckeEric VeysFilip De Keyser

A1 Journal Article in AUTOIMMUNITY REVIEWS

Autoantibodies in rheumatology practice : relevance for diagnosis and associations with clinical features

Isabelle PeeneFilip De KeyserEric Veys

Bowel inflammation in rheumatic diseases: Trigger or consequence

Herman MielantsFilip De Keyser

CARD15 gene polymorphisms in patients with spondyloarthropathies identify a specific phenotype previously related to Crohn's disease

Debby LaukensHarald PeetersDENIS MARICHALBert Vander CruyssenHerman MielantsDirk ElewautPieter DemetterClaude CuvelierM VAN DEN BERGHEPieter Rottiers et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

CARD15 polymorphisms are associated with anti-Saccharomyces cerevisiae antibodies in caucasian Crohn's disease patients

Bert Vander CruyssenHarald PeetersIlse HoffmanDebby LaukensPaul CouckeDENIS MARICHALClaude CuvelierErik RemautEric VeysHerman Mielants et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Case number 34: Relapse of polyarteritis nodosa presenting as isolated and localised lower limb periostitis

P CARRONIlse HoffmanLeen De RyckeIsabelle PeeneEric VeysFilip De KeyserWOUTER BAUTERSMarleen Praet

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Chronically inflamed synovium from spondyloarthropathy and rheumatoid arthritis investigated by protein expression profiling followed by tandem mass spectrometry

Kelly TillemanKatrien Van BenedenAline DhondtIlse HoffmanFilip De KeyserEric VeysDirk ElewautDieter Deforce

A1 Journal Article in PROTEOMICS

Colon mucosa of patients both with spondyloarthritis and Crohn's disease is enriched with macrophages expressing the scavenger receptor CD163

Pieter DemetterMartine De VosJacques Van HuysseDominique BaetenLiesbeth FerdinandeHarald PeetersHerman MielantsEric VeysFilip De KeyserClaude Cuvelier

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Comparing statistics with machine learning models to predict dose increase of infliximab for rheumatoid arthritis patients

Stijn Van LooyBert Vander CruyssenBart WynsJeroen MeeusFilip De KeyserLuc Boullart

Comparison of Machine Learning models for prediction of dose increase in patients with rheumatoid arthritis

Stijn Van LooyJeroen MeeusBart WynsBert Vander CruyssenLuc BoullartFilip De Keyser

DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment

Bert Vander CruyssenStijn Van LooyBart WynsR WESTHOVENSP DUREZM MALAISEL VERBRUGGENN VASTESAEGERA GELDHOFLuc Boullart et al.

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Das28 correlates best with the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients

Bert Vander CruyssenStijn Van LooyR WESTHOVENSP DUREZFilip Van den BoschEM VEYSL DE CLERCKA PERETZM MALAISEJ DEVOGELAER et al.

DAS28 is a robust measure of the physician's clinical judgment of response infliximab therapy

Bert Vander CruyssenStijn Van LooyBart WynsR WESTHOVENSP DUREZF VAN DEN BOSHEric VeysHerman MielantsLISELOTTE DE CLERCKA PERETZ et al.

Diagnostic performance and predictive value of rheumatoid factor, anti-citrullinated peptide antibodies, and the HLA shared epitope for diagnosis of rheumatoid arthritis

Ilse HoffmanIsabelle PeeneH POTTELAnn UnionF HULSTAERTL MEHEUSK LEBEERL DE CLERCQL SCHATTEMANStefaan Poriau et al.

A1 Journal Article in CLINICAL CHEMISTRY

Differential expression and response to anti-TNF alpha treatment of infiltrating versus resident tissue macrophage subsets in autoimmune arthritis

Leen De RyckeDominique BaetenD FOELLElli KruithofEric VeysJ ROTHFilip De Keyser

A1 Journal Article in JOURNAL OF PATHOLOGY

Differential expression of hypoxia activated proteins in synovial tissue of inflammatory arthritides

Kelly TillemanAline DhondtPieter DewintFilip De KeyserDirk ElewautDieter Deforce

Effective immunomodulation of peripheral joint pathology in spondyloarthropathy by etanercept

Elli KruithofLeen De RyckeJ ROTHHerman MielantsFilip Van den BoschFilip De KeyserEric VeysDominique Baeten

Feature selection in the prediction of Infliximab dose increase

Stijn Van LooyJeroen MeeusBart WynsBert Vander CruyssenFilip De KeyserLuc Boullart

Fibrin deimination in synovial tissue is not specific for rheumatoid arthritis but commonly occurs during synovitides

S CHAPUY-REGAUDM SEBBAGDominique BaetenC CLAVELC FOULQUIERFilip De KeyserG SERRE

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Functional haplotypes of PAD14: Relevance for rheumatoid arthritis-specific synovial intracellular citruillinated proteins and anti-citrullinated protein antibodies

Tineke CantaertR COUCKELeen De RyckeEric VeysFilip De KeyserDominique Baeten

Functional haplotypes of PADI4: relevance for rheumatoid arthritis specific synovial intracellular citrullinated proteins and anticitrullinated protein antibodies

Tineke CantaertP COUCKELeen De RyckeEric VeysFilip De KeyserDominique Baeten

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Growth promoting effect of human cartilage glycoprotein-39 (HC gp-39)on synovial fibroblasts

BERNARD VANDOORENG VERHEIJDENE BOSEric VeysFilip De KeyserAM BOOTSDominique Baeten

Histological evidence that infliximab treatment leads to downregulation of inflammation and tissue remodelling of the synovial membrane in spondyloarthropathy

Elli KruithofDominique BaetenFilip Van den BoschHerman MielantsEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Human cartilage glycoprotein-39 (HC gp-39) as growth factor for synovial fibroblasts

BERNARD VANDOORENG VERHEIJDENE BOSEric VeysFilip De KeyserA BOOTSDominique Baeten

Identification of synovial biomarkers of response to treatment in spondyloarthropathy

Elli KruithofLeen De RyckeFilip De KeyserO FITZGERALDI MCINNESPP TAKB BRESNIHANEric VeysDominique Baeten

IgM anti-dsDNA antibodies are the main anti-nuclear reactivity induced by infliximab but not etanercept treatment: biological and clinical implications

Leen De RyckeDominique BaetenElli KruithofEric VeysFilip De Keyser

IgM anti-dsDNA autoantibodies are the main antinuclear reactivity induced by infliximab but not etanercept treatment in vivo: Biological and clinical implications

Leen De RyckeDominique BaetenElli KruithofFilip Van den BoschEric VeysFilip De Keyser

Immunomodulatory effects of etanercept on peripheral joint synovitis in the spondylarthropathies

Elli KruithofLeen De RyckeJ ROTHHerman MielantsFilip Van den BoschFilip De KeyserEric VeysDominique Baeten

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Impact of natural changes in disease activity on synovial histopathology in rheumatoid arthritis

Dominique BaetenJ HOUBIERSElli KruithofBERNARD VANDOORENFilip Van den BoschA BOOTSEric VeysA MILTENBURGFilip De Keyser

Increased systemic and local expression of toll-like receptor 2 and 4 in spondyloarthropathy is downmodulated by tumour necrosis factor alpha blockade

Leen De RyckeBERNARD VANDOORENElli KruithofFilip De KeyserEric VeysDominique Baeten

Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy

Dominique BaetenElli KruithofLeen De RyckeAM BOOTSHerman MielantsEric VeysFilip De Keyser

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Infliximab in ankylosing spondylitis

Filip De Keyser

Editorial material

Infliximab, but not etanercept, induces IgM anti-double-stranded DNA autoantibodies as main antinuclear reactivity : biologic and clinical implications in autoimmune arthritis

Leen De RyckeDominique BaetenElli KruithofFilip Van den BoschEric VeysFilip De Keyser

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Involvement of neurotrophins and their receptors in spondyloarthritis synovitis: relation to inflammation and response to treatment

M RIHLElli KruithofC BARTHELFilip De KeyserEric VeysH ZEIDLERDTY YUJG KUIPERSDominique Baeten

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Juvenile chronic arthritis displays synovial features distinct from both spondyloarthropathy and rheumatoid arthritis

Elli KruithofV VAN DEN BOSSCHELeen De RyckeBERNARD VANDOORENR JOOSDirk ElewautFilip De KeyserEric VeysDominique Baeten

Local production of the cartilage protein melanoma inhibitory activity (MIA) in the inflamed joint: Disease specificity, regulation by IL-1, and association with radiological joint damage

BERNARD VANDOORENMJC VAN LIEROPEric VeysAM BOOTSE BOSFilip De KeyserDominique Baeten

Mannose-binding lectin (MBL2) polymorphisms in rheumatoid arthritis (RA) are not associated with susceptibility or radiological progression rate

Leen De RyckeIsabelle PeeneElli KruithofT Van De CasteeleL NuytinckEric VeysI De CanckFilip De Keyser

Mannose-binding lectin (Mbl2) polymorphisms in rheumatoid arthritis are not associated with susceptibility, radiological progression rate, or serological markers

Leen De RyckeIsabelle PeeneElli KruithofIlse HoffmanBert Vander CruyssenJ JURASL NUYTINCKEric VeysFilip De Keyser

Mannose-binding lectin polymorphisms in rheumatoid arthritis and the associations with radiological progression rate and serological markers

Leen De RyckeIsabelle PeeneElli KruithofT Van De CasteeleLieve NuytinckEric VeysFilip De Keyser

Mannose-binding lectin polymorphisms in rheumatoid arthritis and the associations with radiological progression rate and serological markers

Leen De RyckeIsabelle PeeneElli KruithofT Van De CasteeleLieve NuytinckEric VeysFilip De Keyser

Preliminary evidence for a retardation of structural damage in patients with ankylosing spondylitis continuously treated with infliximab for 4 years

Filip Van den BoschMIEKE DEVINCKElli KruithofIlse HoffmanG VERBRUGGENFilip De KeyserHerman MielantsEric Veys

Presence of rheumatoid factor and antibodies to citrullinated peptides in systemic lupus erythematosus

Ilse HoffmanIsabelle PeeneL CEBECAUERD ISENBERGTWJ HUIZINGAAnn UnionL MEHEUSK DE BOSSCHEREF HULSTAERTEric Veys et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Relative increase in lung volume in fetuses with congenital diaphragmatic hernia treated by fetoscopic endoluminal tracheal occlusion (FETO)

M CANNIEJ JANID VAN SCHOUBROECKFilip De KeyserG MARCHALD GALLOTS DYMARKOWSKIJ DEPREST

Rheumatoid factor, but not anti-cyclic citrullinated peptide antibodies, is modulated by infliximab treatment in rheumatoid arthritis

Leen De RyckeXavier VerhelstElli KruithofFilip Van den BoschIlse HoffmanEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

S100A12-expression is upregulated by TNF and may serve as a marker for the success of anti-TNF therapy

H WITTKOWSKIAK ULFGRENLeen De RyckeFilip De KeyserL KLARESKOGJ ROTHD FOELL

Short and long term synovial immunumodulation by etanercept in spondyloarthropathy

Elli KruithofLeen De RyckeFilip Van den BoschHerman MielantsEric VeysFilip De KeyserDominique Baeten

Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis

Elli KruithofDominique BaetenLeen De RyckeBERNARD VANDOOREND FOELLJ ROTHJD CANETEAM BOOTSEric VeysFilip De Keyser

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase are pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity

Leen De RyckeAP NICHOLASTineke CantaertElli KruithofJD ECHOLSB VANDEKERCKHOVEEric VeysFilip De KeyserDominique Baeten

Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase are pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity

Leen De RyckeAR NICHOLASTineke CantaertElli KruithofJD ECHOLSB VANDEKERCKHOVEEric VeysFilip De KeyserDominique Baeten

Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase as pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity

Leen De RyckeAP NICHOLASTineke CantaertElli KruithofJD ECHOLSBart VandekerckhoveEric VeysFilip De KeyserDominique Baeten

A1 Journal Article in ARTHRITIS AND RHEUMATISM

The cartilage protein Melanoma Inhibitory Activity (MIA) is produced locally in the arthritic joint but does not correlate with radiological joint damage

BERNARD VANDOORENM VAN LIEROPE ROVERSM BRUISTENEric VeysA BOOTSE BOSFilip De KeyserDominique Baeten

The effect of TNFalpha blockade on the antinuclear antibody profile in patients with chronic arthritis: biological and clinical implications

Leen De RyckeDominique BaetenElli KruithofFilip Van den BoschEric VeysFilip De Keyser

A1 Journal Article in LUPUS

Tumor necrosis factor a blockade treatment down-modulates the increased systemic and local expression of toll-like receptor 2 and toll-like receptor 4 in spondylarthropathy

Leen De RyckeBERNARD VANDOORENElli KruithofFilip De KeyserEric VeysDominique Baeten

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Tumor necrosis factor-alpha blockade in ankylosing spondylitis: a potent but expensive anti-inflammatory treatment or true disease modification?

Filip Van den BoschFilip De KeyserHerman MielantsEric Veys

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

2004

Association of CD163+ macrophages and local production of soluble CD163 with decreased lymphocyte activation in spondylarthropathy synovitis

Dominique BaetenHJ MOLLERJ DELANGHEEric VeysSK MOESTRUPFilip De Keyser

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Building decision tree classifiers using a Kohonen self-organizing map

Stijn Van LooyBart WynsLuc BoullartDominique BaetenIlse HoffmanFilip De Keyser

Case number 29: Ochronosis: synovial histopathological characteristics

Elli KruithofDominique BaetenEric VeysFilip De KeyserStephanus SuykensLieven De WildeRené Verdonk

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Detection of major histocompatibility complex/human cartilage gp-39 complexes in rheumatoid arthritis synovitis as a specific and independent histologic marker

Dominique BaetenPGA STEENBAKKERSAMW RIJNDERSAM BOOTSEric VeysFilip De Keyser

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Diagnostic classification of spondylarthropathy and rheumatoid arthritis by synovial histopathology - A prospective study in 154 consecutive patients

Dominique BaetenElli KruithofLeen De RyckeBERNARD VANDOORENBart WynsLuc BoullartIlse HoffmanAM BOOTSEric VeysFilip De Keyser

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Diagnostic performance and predictive value of serum markers for the diagnosis of rheumatoid arthritis

Ilse HoffmanIsabelle PeeneAnn UnionL MEHEUSL DE CLERCQL SCHATTEMANS PORIAUHerman MielantsEric VeysFilip De Keyser

Differential expression and response to infliximab treatment of specific macrophage subsets in inflammatory synovitis

Leen De RyckeDominique BaetenD FOELLElli KruithofEric VeysJ ROTHFilip De Keyser

Effect of infliximab treatment on T cell cytokine responses in spondylarthropathy: comment on the article by Zou et al

Dominique BaetenBERNARD VANDOORENLeen De RyckeEric VeysFilip De Keyser

A1 Journal Article in ARTHRITIS AND RHEUMATISM

False positivity of rheumatoid factor and antibodies to citrullinated peptides in systemic lupus erythematosus

Ilse HoffmanIsabelle PeeneAnn UnionL MEHEUST HUIZINGAL CEBECAUERD ISENBERGK DE BOSSCHEREF HULSTAERTEric Veys et al.

History and diagnostic value of antibodies to citrullinated proteins in rheumatoid arthritis

Isabelle PeeneLeen De RyckeDominique BaetenIlse HoffmanEric VeysFilip De Keyser

A1 Journal Article in INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Identification of synovial histopathological parameters for diagnostic classification of inflammatory arthritis by SAM analysis and neural networks

Dominique BaetenBart WynsStijn Van LooyIlse HoffmanEric VeysLuc BoullartFilip De Keyser

Involvement of matrix metalloproteinases and their inhibitors in peripheral synovitis and down-regulation by tumor necrosis factor alpha blockade in spondylarthropathy

BERNARD VANDOORENElli KruithofDTY YUM RIHLJR GULeen De RyckeFilip Van den BoschEric VeysFilip De KeyserDominique Baeten

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Prediction of arthritis using a modified Kohonen mapping and case based reasoning

Bart WynsLuc BoullartS SETTEDominique BaetenIlse HoffmanFilip De Keyser

A1 Journal Article in ENGINEERING APPLICATIONS OF ARTIFICIAL INTELLIGENCE

Prediction of diagnosis in patients with early arthritis using a combined Kohonen mapping and instance-based evaluation criterion

Bart WynsS SETTELuc BoullartDominique BaetenIlse HoffmanFilip De Keyser

A1 Journal Article in ARTIFICIAL INTELLIGENCE IN MEDICINE

Protein expression profiling of inflamed synovial tissue in rheumatoid arthritis, spondyloarthropathy and osteoarthritis

Kelly TillemanAline DhondtIlse HoffmanFilip De KeyserEric VeysDieter DeforceDirk Elewaut

Radiological sacroiliitis is linked with CARD15 gene polymorphisms in patients with Crohn's disease

Bert Vander CruyssenHarald PeetersDebby LaukensP COUCKEHerman MielantsMartine De VosFilip De Keyser

Radiological sacroiliitis, a hallmark of spondylitis, is linked with CARD15 gene polymorphisms in patients with Crohn's disease

Harald PeetersBert Vander CruyssenDebby LaukensPaul CouckeDENIS MARICHALMARTINA VAN DEN BERGHEClaude CuvelierErik RemautHerman MielantsFilip De Keyser et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Rheumatoid factor and anticitrullinated protein antibodies in rheumatoid arthritis: diagnostic value, associations with radiological progression rate, and extra-articular manifestations

Leen De RyckeIsabelle PeeneIlse HoffmanElli KruithofAnn UnionL MEHEUSK LEBEERBart WynsC VINCENTHerman Mielants et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Serum levels of matrix metalloproteinase 3 and macrophage colony-stimulating factor 1 correlate with disease activity in ankylosing spondylitis

CH YANGJR GUM RIHLDominique BaetenF HUANGMS ZHAOHW ZHANGWP MAKSYMOWYCHFilip De KeyserEric Veys et al.

A1 Journal Article in ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH

Serum MRP8/MRP14 as a biomarker for inflammation in autoimmune arthritis

Leen De RyckeDominique BaetenD FOELLElli KruithofEric VeysJ ROTHFilip De Keyser

Specific antinuclear antibodies are associated with clinical features in systemic lupus erythematosus

Ilse HoffmanIsabelle PeeneL MEHEUSTWJ HUIZINGAL CEBECAUERD ISENBERGK DE BOSSCHEREF HULSTAERTEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Structure-modifying capacity of anti-tumour necrosis factor-alpha therapy in Ankylosing spondylitis

Filip De KeyserDominique BaetenFilip Van den BoschELLI KRUITHOFG VERBRUGGENHerman MielantsE VEYS

A1 Journal Article in DRUGS

Synovial tissue proteomics in rheumatoid arthritis and spondyloarthropathy

Kelly TillemanKatrien Van BenedenFilip De KeyserEric VeysDieter DeforceDirk Elewaut

Technical validation of cDNA based microarray as screening technique to identify candidate genes in synovial tissue biopsy specimens from patients with spondyloarthropathy

M RIHLDominique BaetenN SETAJ GUFilip De KeyserEric VeysJG KUIPERSH ZEIDLERDTY YU

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

The effect of infliximab on skin lesions in a patient with scleroderma (CREST)

Leen De RyckeDominique BaetenFilip Van den BoschHerman MielantsFilip De KeyserEric Veys

The histopathology of spondyloarthropathy

Dominique BaetenFilip De Keyser

A1 Journal Article in CURRENT MOLECULAR MEDICINE

The lunar achilles as a screening tool for osteoporosis: Comparison with spine DXA

S PORIAUP GEUSENSFilip Van den BoschFilip De Keyser

The presence of CARD15 polymorphisms is linked with higher ASCA titers in Crohn's disease

Harald PeetersBert Vander CruyssenDebby LaukensP COUCKEIlse HoffmanFilip De KeyserMartine De Vos

The presence of deiminated fibrin in the synovial membrane is not specific for rheumatoid arthritis

S CHAPUY-REGAUDM SEBBAGDominique BaetenC CLAVELFilip De KeyserG SERRE

Tumour necrosis factor alpha independent disease mechanisms in rheumatoid arthritis: a histopathological study on the effect of infliximab on rheumatoid nodules

Dominique BaetenFilip De KeyserEric VeysY THEATEFA HOUSSIAUP DUREZ

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Weight analysis of a topological map to determine parameter importance

Bart WynsStijn Van LooyLuc BoullartDominique BaetenIlse HoffmanFilip De Keyser

2003

Anti-Saccharomyces cerevisiae IgA antibodies are raised in ankylosing spondylitis and undifferentiated spondyloarthropathy

Ilse HoffmanPieter DemetterMarc PeetersMartine De VosHerman MielantsEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Antinuclear antibodies following infliximab treatment in patients with rheumatoid arthritis or spondylarthropathy

Leen De RyckeElli KruithofNancy Van DammeIlse HoffmanN VAN DEN BOSSCHEFilip Van den BoschEric VeysFilip De Keyser

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Association between ASCA-positivity and carrier of a CARD-15 mutation in patients with Crohn's disease

B VAN DER CRUYSSENFilip De KeyserHarald PeetersM VAN DEN BERGHED MARICHALIlse HoffmanT VAN OOSTVELDTDebby LaukensErik RemautL STEIDLER et al.

CARD15 mutations in patients with spondyloarthropathy are linked with disease progression and evolution to Crohn's disease

Martine De VosDebby LaukensDENIS MARICHALM VAN DEN BERGHEHarald PeetersDirk ElewautHerman MielantsFilip De KeyserClaude CuvelierEric Veys et al.

Changes in rheumatoid factor reflect the inflammatory response (CRP and ESR) to infliximab treatment

Leen De RyckeElli KruithofNancy Van DammeIlse HoffmanFilip Van den BoschEric VeysFilip De Keyser

Crohn's disease patients with CARD15 variants have higher risk of developing axial joint involvement

Martine De VosHarald PeetersBert Vander CruyssenDebby LaukensDenis MarichalMarthe VandenbergheT Van OostveldtDirk ElewautFilip De KeyserClaude Cuvelier et al.

Cutaneous polyarteritis nodosa: A distinct entity

Isabelle PeeneLeen De RyckeMarleen PraetEric VeysJean NaeyaertFilip De Keyser

Effect of infliximab on matrix metalloprotelinase (MMP)-1,-2,-3 and tissue inhibitors of matrix metalloproteinases (TIMP)-1,-2 in spondyloarthropathy (SpA) synovitis

BERNARD VANDOORENElli KruithofFilip De KeyserDTY YUEric VeysDominique Baeten

Infliximab in patients who have spondyloarthropathy: clinical efficacy, safety and biological immunomodulation

Filip De KeyserDominique BaetenFilip Van den BoschElli KruithofHerman MielantsEric Veys

A2 Journal Article in Rheumatic diseases Clin. N. Am.

Infliximab in patients who have spondyloarthropathy: clinical efficacy, safety, and biological immunomodulation

Filip De KeyserDominique BaetenFilip Van den BoschElli KruithofHerman MielantsEric Veys

A1 Journal Article in RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Local production of soluble CD163 in the spondyloarthropathic joint

Dominique BaetenHJ MOLLERJ DELANGHEEric VeysSK MOESTRUPFilip De Keyser

Localisation of MHC Class II/HC gp-39 complexes in synovia of rheumatoid arthritis patients using complex-specific monoclonal antibodies

Dominique BaetenPGA STEENBAKKERSE ROVERSEric VeysAMW RIJNDERSJ MEIJERINKFilip De KeyserA BOOTS

Localization of MHC class II/human cartilage glycoprotein-39 complexes in synovia of rheumatoid arthritis patients using complex-specific monoclonal antibodies

PGA STEENBAKKERSDominique BaetenE ROVERSEric VeysAWM RIJNDERSJ MEIJERINKFilip De KeyserAMH BOOTS

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Microarray data mining uncovers neurotrophins and their receptors as potential mediators in spondyloarthritis (SpA)

M RIHLJG KUIPERSFilip De KeyserEric VeysH ZEIDLERDTY YUDominique Baeten

Microarrays uncover serum elisa levels of metalloproteinase-3 (MMP3) as a useful parameter to measure disease activity in anky-losing spondylitis (AS)

F HUANGMS ZHAOCH YANGHW ZHANGJR GUM RIHLDominique BaetenFilip De KeyserEric VeysDTY YU

Myeloid-related protein (MRP) 8 and MRP 14 in rheumatoid arthritis and spondyloarthropathy

Leen De RyckeDominique BaetenD FOELLEric VeysFilip De KeyserJ ROTH

Peptidylarginine deiminase isoforms expressed in the synovial membrane of rheumatoid arthritis patients

S CHAPUY-REGAUDM SEBBAGR NACHATDominique BaetenV FOULQUIERM SIMONT SENSHUM YAMADAH TAKAHARAFilip De Keyser et al.

Prediction of arthritis using a modified Kohonen mapping and case based learning

Luc BoullartStefan SetteBart WynsDominique BaetenIlse HoffmanFilip De Keyser

Presence of anti-RNP-A and anti-RNP-C antibodies is inversely associated with renal symptoms of systemic lupus erythematosus

I HOFFMANIsabelle PeeneL MEHEUSK DE BOSSCHEREF HULSTAERTTWJ HUIZINGAL CEBECAUERD ISENBERGEric VeysFilip De Keyser

Rheumatoid factor and anti-citrullinated peptide antibodies in rheumatoid arthritis: Diagnostic value and association with radiological progression

Leen De RyckeIsabelle PeeneIlse HoffmanElli KruithofAnn UnionL MEHEUSEric VeysFilip De Keyser

Serum MRP 8/14 is an inflammatory marker for chronic arthritis, partially originating from the inflamed joint

Leen De RyckeDominique BaetenD FOELLEric VeysFilip De KeyserJ ROTH

Systematic safety follow up in a cohort of 107 patients with spondyloarthropathy treated with infliximab: a new perspective on the role of host defence in the pathogenesis of the disease?

Dominique BaetenElli KruithofFilip Van den BoschN VAN DEN BOSSCHEA HERSSENSHerman MielantsFilip De KeyserEric Veys

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Systematic safety follow-up in a cohort of 107 patients with spondylarthropathy treated with Infliximab: a new perspective of the role of host defence in the pathogenesis of the disease?

Dominique BaetenElli KruithofFilip Van den BoschN VAN DEN BOSSCHEMarianne HerssensHerman MielantsFilip De KeyserEric Veys

A2 Journal Article in Annals of Rheumatic Diseases

The diagnostic value of synovial histopathology in undifferentiated inflammatory arthritis: a prospective study in 154 consecutive patients

Dominique BaetenElli KruithofIlse HoffmanLeen De RyckeBERNARD VANDOORENEric VeysFilip De Keyser

The gut in ankylosing spondylitis and other spondyloarthropathies: Inflammation beneath the surface

Filip De KeyserHerman Mielants

Editorial material

The presentation of the immunodominant epitope of HC gp-39 in the context of the RA-associated HLA class II molecules is specific for RA synovium

Dominique BaetenP STEENBAKKERSA BOOTSEric VeysFilip De Keyser

The use of neural network algorithms for the classification of undifferentiated arthritis by synovial histopathology

Dominique BaetenBart WynsIlse HoffmanS SETTELuc BoullartFilip De Keyser

The use of neural network algorithms for the classification of undifferentiated arthritis by synovial histopathology

Dominique BaetenBart WynsIlse HoffmanS SETTELuc BoullartFilip De Keyser

2002

A 588-gene microarray analysis of the peripheral blood mononuclear cells of spondyloarthropathy patients.

J GUE MARKER-HERMANNDominique BaetenWC TSAID GLADMANM XIONGH DEISTERJG KUIPERSF HUANGYW SONG et al.

A1 Journal Article in RHEUMATOLOGY

Ankylosing spondylitis and bowel disease.

Dominique BaetenFilip De KeyserHerman MielantsEric Veys

A1 Journal Article in BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Anti-Ro52 reactivity is an independent and additional serum marker in connective tissue disease.

Isabelle PeeneL MEHEUSS DE KEYSERR HUMBELEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Clues to pathogenesis of spondyloarthropathy derived from synovial fluid mononuclear cell gene expression profiles.

J GUM RIHLE MARKER-HERMANNDominique BaetenJG KUIPERSYW SONGWP MAKSYMOWYCHR BURGOS-VARGASEric VeysFilip De Keyser et al.

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Detection of specific antinuclear reactivities in patients with negative anti-nuclear antibody immunofluorescence screening tests.

Ilse HoffmanIsabelle PeeneEric VeysFilip De Keyser

A1 Journal Article in CLINICAL CHEMISTRY

Diagnostic associations in a large and consecutively identified population positive for anti-SSA and/or anti-SSB: the range of associated diseases differs according to the getailed serotype.

Isabelle PeeneL MEHEUSEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Dynamic T cell receptor clonotype changes in synovial tissue of patients with early rheumatoid arthritis : effects of treatment with cyclosporin A (Neoral®)

Ann VanderBorghtFilip De KeyserPiet GeusensMarc De BackerMichel MalaiseDominique BaetenFilip Van den BoschEric VeysJef RausPiet Stinissen

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Gut inflammation and spondyloarthropathies.

Filip De KeyserDominique BaetenHerman MielantsMartine De VosClaude CuvelierEric Veys

A2 Journal Article in CURRENT RHEUMATOLOGY REPORTS

Identification of citrullinated rheumatoid arthritis-specific epitopes in natural filaggrin relevant for antifilaggrin autoantibody detection by line immunoassay.

Ann UnionL MEHEUSRL HUMBELK CONRADG STEINERH MOEREELSH POTTELG SERREFilip De Keyser

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Immune linkages between inflammatory bowel disease and spondyloarthropathies.

Dominique BaetenFilip De KeyserHerman MielantsEric Veys

A1 Journal Article in CURRENT OPINION IN RHEUMATOLOGY

Increase in lymphoid follicles and leukocyte adhesion molecules emphasizes a role for the gut in spondyloarthropathy pathogenesis.

Pieter DemetterJacques Van HuysseFilip De KeyserNancy Van DammeG VERBRUGGENHerman MielantsMartine De VosEric VeysClaude Cuvelier

A1 Journal Article in JOURNAL OF PATHOLOGY

Influence of the gut and cytokine patterns in spondyloarthropathy.

Dominique BaetenFilip De KeyserNancy Van DammeEric VeysHerman Mielants

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Is expression of intracellular citrullinated proteins in synovial tissue specific for rheumatoid arthritis? Comment on the article by Baeten et al - Reply.

Dominique BaetenEric VeysFilip De Keyser

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Macrophages expressing the scavenger receptor CD163: a link between immune alterations of the gut and synovial inflammation in spondyloarthropathy.

Dominique BaetenPieter DemetterClaude CuvelierElli KruithofNancy Van DammeMartine De VosEric VeysFilip De Keyser

A1 Journal Article in JOURNAL OF PATHOLOGY

Randomized double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor α (infliximab) versus placebo in active spondylarthropathy

Filip Van den BoschElli KruithofDominique BaetenAnnemie HerssensFilip De KeyserHerman MielantsEric Veys

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Repeated infusions of infliximab, a chimeric anti-TNFα monoclonal antibody, in patients with active spondyloarthropathy: one year follow up

Elli KruithofFilip Van den BoschDominique BaetenA HerssensFilip De KeyserHerman MielantsEric Veys

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Successful use of infliximab in a patient with treatment resistant spondyloarthropathy related uveitis

Elli KruithofPhilippe KestelynC ElewautDirk ElewautFilip Van den BoschHerman MielantsEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Tenosynovitis with acute onset: unexpected giant cell tumour of the tendon sheath.

Elli KruithofDominique BaetenP DIERCKXSENSEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

The cutting edge of spondyloarthropathy research in the millennium.

K GRANFORSE MARKER-HERMANFilip De KeyserMA KHANEric VeysD YU

A2 Journal Article in ARTHRITIS AND RHEUMATISM

2001

Characteristic macro- and microscopic aspect of the synovial membrane in crystal induced arthritis

Filip Van den BoschDominique BaetenElli KruithofFilip De KeyserEric Veys

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Current use of biologicals for the treatment of spondyloarthropathies.

Filip De KeyserHerman MielantsEric Veys

A2 Journal Article in Exp Opin Pharmacother

Detection and identification of antinuclear antibodies (ANA) in a large and consecutive cohort of serum samples referred for ANA testing.

Isabelle PeeneL MEHEUSEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Effects of anti-tumor necrosis factor alpha on synovium in patients with spondylarthropathy: Comment on the article by Baeten et al - Reply.

Dominique BaetenElli KruithofFilip Van den BoschHerman MielantsEric VeysFilip De Keyser

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Flow cytometric analysis of gut mucosal lymphocytes supports an impaired Th1 cytokine profile in spondyloarthropathy.

Nancy Van DammeMartine De VosDominique BaetenPieter DemetterHerman MielantsG VERBRUGGENC CUVELIEREric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Gut mucosal T cell lines from ankylosing spondylitis patients are enriched with alpha E beta 7 integrin.

Nancy Van DammeDirk ElewautDominique BaetenPieter DemetterClaude CuvelierG VERBRUGGENHerman MielantsEric VeysMartine De VosFilip De Keyser

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Immunomodulatory effects of anti-tumor necrosis factor α therapy on synovium in spondylarthropathy: histologic findings in eight patients from an open-label pilot study

Dominique BaetenElli KruithofFilip Van den BoschPieter DemetterNancy Van DammeClaude CuvelierMartine De VosHerman MielantsEric VeysFilip De Keyser

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Impaired Th1 cytokine production in spondyloarthropathy is restored by anti-TNFα

Dominique BaetenNancy Van DammeFilip Van den BoschElli KruithofMartine De VosHerman MielantsEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

New treatment options in spondyloarthropathies : increasing evidence for significant efficacy of anti-tumor necrosis factor therapy.

J BraunFilip De KeyserJ BrandtHerman MielantsJ SieperEric Veys

A1 Journal Article in CURRENT OPINION IN RHEUMATOLOGY

Phenotypical and functional characterisation of human intestinal lymphocytes from patients with spondyloarthropathy

Nancy Van DammeFilip De KeyserMartine De Vos

Specific presence of intracellular citrullinated proteins in rheumatoid arthritis synovium - Relevance to antifilaggrin autoantibodies.

Dominique BaetenIsabelle PeeneAnn UnionL MEHEUSM SEBBAGG SERREEric VeysFilip De Keyser

A1 Journal Article in ARTHRITIS AND RHEUMATISM

The proportion of Th1 cells, which prevail in gut mucosa, is decreased in inflammatory bowel syndrome.

Nancy Van DammeFilip De KeyserPieter DemetterDominique BaetenHerman MielantsG VERBRUGGENClaude CuvelierEric VeysMartine De Vos

A1 Journal Article in CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The stress protein BiP is overexpressed and is a major B and T cell target in rheumatoid arthritis.

S BLASSAnn UnionJ RAYMACKERSF SCHUMANNU UNGETHUMS MULLER-STEINBACHFilip De KeyserJM ENGELGR BURMESTER

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Treatment of active spondyloarthropathy with infliximab, the chimeric monoclonal antibody to tumour necrosis factor alpha.

Filip Van den BoschDominique BaetenElli KruithofFilip De KeyserHerman MielantsEric Veys

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

2000

Broadening of the T cell receptor spectrum among rheumatoid arthritis synovial cell-lines in relation to disease duration

Dirk ElewautFilip De KeyserFilip Van den BoschAugust VerbruggenEric Veys

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Chemical agents and enzymes used for the extraction of gut lymphocytes influence flow cytometric detection of T cell surface markers.

Nancy Van DammeDominique BaetenMartine De VosPieter DemetterDirk ElewautHerman MielantsG VERBRUGGENClaude CuvelierEric VeysFilip De Keyser

A1 Journal Article in JOURNAL OF IMMUNOLOGICAL METHODS

Comparative study of the synovial histology in rheumatoid arthritis, spondyloarthropathy, and osteoarthritis: influence of disease duration and activity

Dominique BaetenPieter DemetterClaude CuvelierFilip Van den BoschElli KruithofNancy Van DammeAugust VerbruggenHerman MielantsEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Crohn's disease associated with spondyloarthropathy: effect of TNF-alpha blockade with infliximab on articular symptoms.

Filip Van den BoschElli KruithofMartine De VosFilip De KeyserHerman Mielants

A1 Journal Article in LANCET

Effects of a loading dose regimen of three infusions of chimeric monoclonal antibody to tumour necrosis factor α (infliximab) in spondyloarthropathy: an open pilot study

Filip Van den BoschElli KruithofDominique BaetenFilip De KeyserHerman MielantsEric Veys

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Focal up-regulation of E-cadherin-catenin complex in inflamed bowel mucosa but reduced expression in ulcer associated cell lineage.

Pieter DemetterMartine De VosNancy Van DammeDominique BaetenDirk ElewautS VERMEULENMarcus MareelGillian BullockHerman MielantsG VERBRUGGEN et al.

A1 Journal Article in AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Human cartilage gp-39+, CD16+monocytes in peripheral blood and synovium : correlation with joint destruction in rheumatoid arthritis

Dominique BaetenAnnemieke MH BootsPeter GA SteenbakkersDirk ElewautEbo BosGijs FM VerheijdenAugust VerbruggenAndré MM MiltenburgAnthonius WM RijndersEric Veys et al.

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Immune-mediated pathology following hepatitis B vaccination. Two cases of polyarteritis nodosa and one case of pityriasis rosea-like drug eruption.

Filip De KeyserJM NAEYAERTP HINDRICKXDirk ElewautP VERPLANCKEIsabelle PeeneMarleen PraetEric Veys

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Immunopathology of the synovial membrane in autoimmune arthritis

Dominique BaetenFilip De KeyserEric Veys

Opportunities for immune modulation in the spondyloarthropathies with special reference to gut inflammation.

Filip De KeyserNancy Van DammeMartine De VosHerman MielantsEric Veys

A1 Journal Article in INFLAMMATION RESEARCH

Sensitivity of the HEp-2000 substrate for the detection of Anti-SSA/Ro60 antibodies.

Isabelle PeeneW VAN AELM VANDENBOSSCHET VERVAETEric VeysFilip De Keyser

A1 Journal Article in CLINICAL RHEUMATOLOGY

Spondyloarthropathy is underestimated in inflammatory bowel disease: Prevalence and HLA association.

Kurt De VlamHerman MielantsClaude CuvelierFilip De KeyserEric VeysMartine De Vos

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Subclinical gut inflammation in spondyloarthropathy patients is associated with upregulation of the E-cadherin/catenin complex.

Pieter DemetterDominique BaetenFilip De KeyserMartine De VosNancy Van DammeG VERBRUGGENS VERMEULENMarcus MareelDirk ElewautHerman Mielants et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies.

H BRAHMSJ RAYMACKERSAnn UnionFilip De KeyserL MEHEUSR LUHRMANN

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

1999

Anti-perinuclear factor compared with the so called "antikeratin" antibodies and antibodies to human epidermis filaggrin, in the diagnosis of arthritides.

C VINCENTFilip De KeyserC MASSON-BESSIEREM SEBBAGEric VeysG SERRE

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Crohn's disease and ulcerative colitis show different distribution patterns of CD83 positive dendritic cells

Pieter DemetterMartine De VosNancy Van DammeDominique BaetenHerman MielantsB LelieAugust VerbruggenFilip De KeyserEric VeysClaude Cuvelier

Effects of chemical agents and enzymes on lymphocyte surface markers

Nancy Van DammeDominique BaetenMartine De VosPieter DemetterDirk ElewautHerman MielantsAugust VerbruggenClaude CuvelierEric VeysFilip De Keyser

High frequency of 'missed' HLA-B loci by serologic determination in patients with spondyloarthropathy and chronic gut inflammation

Dirk ElewautHerman MielantsB VandekerckhoveAugust VerbruggenFilip De KeyserClaude CuvelierMartine De VosK GranforsEric Veys

Inflammatory arthropathy and inflammatory bowel disease

Martine De VosHerman MielantsFilip De KeyserC CUVELIERE VEYS

Inflammatory bowel disease and subclinical gut inflammation in spondyloarthropathy patients are associated with increased expression of the E-cadherin/catenin complex

Pieter DemetterMartine De VosDominique BaetenNancy Van DammeFilip De KeyserDirk ElewautS VermeulenMarcus MareelAugust VerbruggenHerman Mielants et al.

Inflammatory bowel disease and subclinical gut inflammation in spondyloarthropathy patients are associated with increased expression of the E-cadherin/catenin complex

Pieter DemetterMartine De VosDominique BaetenNancy Van DammeFilip De KeyserDirk ElewautS VermeulenMarcus Mareel

Intestinal mucosa of patients with spondyloarthropathy is enriched with T cells carrying alpha E beta 7 integrin, even in the absence of histologically defined inflammation

Dirk ElewautNancy Van DammeDominique BaetenPieter DemetterS SasMartine De VosClaude CuvelierAugust VerbruggenHerman MielantsFilip De Keyser et al.

Multicenter validation of recombinant, natural and synthetic antigens used in a single multiparameter assay for the detection of specific anti-nuclear autoantibodies in connective tissue disorders.

L MEHEUSWJ VAN VENROOIJA WIIKPJ CHARLESAG TZIOUFASO MEYERG STEINERD GIANOLAS BOMBARDIERIAnn Union et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Needle arthroscopy of the knee with synovial biopsy sampling: technical experience in 150 patients

Dominique BaetenFilip Van den BoschDirk ElewautA StuerEric VeysFilip De Keyser

A1 Journal Article in CLINICAL RHEUMATOLOGY

Polyarteritis nodosa mimicking polymyalgia rheumatica.

Elli KruithofDirk ElewautJean NaeyaertMarleen PraetHerman MielantsEric VeysFilip De Keyser

A1 Journal Article in CLINICAL RHEUMATOLOGY

Proinflammatory cytokine production and cell adhesion molecule expression compared in rheumatoid nodules and synovial membranes : comment on the article by Wikaningrum et al.

Dirk ElewautFilip De KeyserAugust VerbruggenEric Veys

A1 Journal Article in ARTHRITIS AND RHEUMATISM

T cell cytokines in gut mucosa of patients with spondyloarthropathy reflect immune alterations in Crohn's disease

Nancy Van DammeMartine De VosDominique BaetenPieter DemetterDirk ElewautClaude CuvelierHerman MielantsAugust VerbruggenEric VeysFilip De Keyser

1998

A comparative phenotypical analysis of rheumatoid nodules and rheumatoid synovium with special reference to adhesion molecules and activation markers.

Dirk ElewautFilip De KeyserN DE WEVERDominique BaetenNancy Van DammeG VERBRUGGENClaude CuvelierEric Veys

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Altered expression of ocEß7 integrin on intra-epithelial and lamina propria lymphocytes in patients with Crohn's disease

Dirk ElewautNancy Van DammeFilip De KeyserDominique BaetenPascale De PaepeHans Van VlierbergheHerman MielantsClaude CuvelierAugust VerbruggenEric Veys et al.

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Bone and joint diseases in inflammatory bowel disease

Martine De VosFilip De KeyserHerman MielantsClaude CuvelierEric Veys

A1 Journal Article in ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Bowel inflammation and the spondyloarthropathies.

Filip De KeyserDirk ElewautMartine De VosKurt De VlamClaude CuvelierHerman MielantsEric Veys

A1 Journal Article in RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

De pathofysiologie van lupus erythematodes.

Raymond VanholderFilip De KeyserJohan KipsMarleen PraetJean Naeyaert

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Distinctive activated cellular subsets in colon from patients with Crohn's disease and ulcerative colitis

Dirk ElewautFilip De KeyserClaude CuvelierAI LazarovitsHerman MielantsAugust VerbruggenS SasMartine De VosEric Veys

A1 Journal Article in SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Effects of chemical agents and enzymes on the detection of lymphocyte surface markers.

Nancy Van DammeDominique BaetenMartine De VosPieter DemetterDirk ElewautHerman MielantsG VERBRUGGENC CUVELIEREM VEYSFilip De Keyser

A2 Journal Article in Clinical and Experimental Immunology

Enrichment of T cells carrying 137 integrins in inflamed synovial tissue from patients with early spondyloarthropathy, compared to rheumatoid arthritis

Dirk ElewautFilip De KeyserFilip Van den BoschAI LazarovitsMartine De VosClaude CuvelierAugust VerbruggenHerman MielantsEric Veys

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Extracutane manifestaties van Lupus.

Marleen PraetJean NaeyaertJohan KipsFilip De KeyserRaymond Vanholder

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Increased expression of E 7 integrin in uninflamed mucosa of patients with spondyloarthropathy

Dirk ElewautNancy Van DammeDominique BaetenPieter DemetterS SASMartine De VosC CUVELIERG VERBRUGGENHerman MielantsFilip De Keyser et al.

A2 Journal Article in Gastroenterology, 1998

Isolation of colonie mucosal lamina propria and intra-epithelial lymphocytes : mechanical versus enzymatic isolation

Nancy Van DammeDominique BaetenFilip De KeyserPieter DemetterDirk ElewautMartine NeckebroekHans Van VlierbergheHerman MielantsG. VerbruggenC. Cuvelier et al.

A2 Journal Article in JOURNAL OF IMMUNOLOGICAL METHODS

Upregulation of E-cadherin and associated molecules (a-, ß- and y-catenins) in inflamed bowel mucosa

Pieter DemetterMartine De VosNancy Van DammeDominique BaetenE CESMELIDirk ElewautS VERMEULENM MAREELGillian BullockHerman Mielants et al.

A2 Journal Article in Am. J. Pathol, 1998

1997

De spondyloarthropathieën en hun relatie met inflammatoir darmlijden.

Filip De Keyser

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Dominant T cell receptor rearrangements in interleukin 2 expanded lymphocytes from rheumatoid nodules suggest antigen driven T cell activation in situ.

Filip De KeyserDirk ElewautJPM OVERMEERGRAUSP VANDENBROEKAWM RIJNDERSEric Veys

A1 Journal Article in JOURNAL OF RHEUMATOLOGY

Extra-intestinal manifestations of enteropathies : why are the joints involved?

Dirk ElewautK GranforsFilip De KeyserIlse HoffmanEric Veys

A2 Journal Article in RHEUMATOLOGY IN EUROPE

Human cartilage glycoprotein-39 as a candidate autoantigen in rheumatoid arthritis.

GFM VERHEIJDENAWM RIJNDERSE BOSCJJC DEROOCJ VANSTAVERENAMM MILTENBURGJH MEIJERINKDirk ElewautFilip De KeyserEric Veys et al.

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Immunopathology of the enteropathies

Claude CuvelierN De WeverDirk ElewautK BensbahoFilip De Keyser

A2 Journal Article in RHEUMATOLOGY IN EUROPE

Selection of self-reactive peptides within human aggrecan by use of a HLA-DRB1*0401 peptide binding motif.

AMH BOOTSGFM VERHEIJDENR SCHONINGHCJ VAN STAVERENE BOSDirk ElewautFilip De KeyserEric VeysI JOOSTENAWM RIJNDERS

A1 Journal Article in JOURNAL OF AUTOIMMUNITY

Specific immune activation in chronic arthritis and molecular targets for immune modulation

Dirk ElewautEric VeysFilip De Keyser

The immunological basis of inflammatory bowel disease

Martine De VosFilip De KeyserClaude Cuvelier

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

1996

Etiological factors and underlying conditions in patients with leucocytoclastic vasculitis

L GyselbrechtFilip De KeyserK OngenaeJean NaeyaertMarleen PraetEric Veys

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Polyarteritis nodosa and the antiphospholipid syndrome.

Renaat SchoonjansB VANVLEMS WEYERSFilip De KeyserMarleen PraetJacques VersieckAndré Elewaut

A1 Journal Article in CLINICAL RHEUMATOLOGY

The gut associated addressins : lymphocyte homing in the gut

Filip De KeyserDirk ElewautNathalie De WeverKhalid BensbahoClaude Cuvelier

A1 Journal Article in BAILLIERES CLINICAL RHEUMATOLOGY

1995

Churg-Strauss-syndrome presenting as polymyositis.

K DEVLAMFilip De KeyserS GOEMAEREMarleen PraetEric Veys

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

THE ROLE OF T-CELLS IN RHEUMATOID-ARTHRITIS.

Filip De KeyserDirk ElewautJ VERMEERSCHN DEWEVERClaude CuvelierEric Veys

A1 Journal Article in CLINICAL RHEUMATOLOGY

1994

An optimized method for routine HLA-B27 screening using flow cytometry.

F HULSTAERTJ ALBRECHTI HANNETP LANCASTERL BUCHNERJ KUNZA FALKENRODTM TONGIOFilip De KeyserEric Veys et al.

A1 Journal Article in CYTOMETRY

Classificatie en histopathologie van vasculitiden.

Marleen PraetFilip De KeyserJ NAEYAERTJ KEPSRaymond VanholderJan De BleeckerEric Veys

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Monoclonal-antibody therapy in rheumatoid-arthritis.

Filip De KeyserDirk ElewautAnne-Marie MalfaitEric Veys

A1 Journal Article in CLINICAL IMMUNOTHERAPEUTICS

Pathologie en reumatologische manifestaties bij sarcoidose.

Filip De KeyserEric Veys

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Second conference on spondylarthropathies and the gut - meeting report

Herman MielantsEric VeysFilip De KeyserG GHYSELENA MALFATT

Vasculitis: een morfologische benadering van een multidisciplinair probleem

Marleen PraetFilip De KeyserJean NaeyaertJohan KipsRaymond VanholderRomain PauwelsEric Veys

Vasculitis: een multidisciplinaire kijk.

Filip De KeyserEric Veys

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

1993

CHANGES IN ANTINUCLEAR SEROLOGY IN PATIENTS WITH SPONDYLARTHROPATHY UNDER SULFASALAZINE TREATMENT.

Filip De KeyserHerman MielantsJ PRAETS GOEMAEREEric Veys

A1 Journal Article in BRITISH JOURNAL OF RHEUMATOLOGY

Detection and identification of antinuclear autoantibodies in the serum of normal blood donors.

K DEVLAMFilip De KeyserG VERBRUGGENM VANDENBOSSCHEB VANNEUVILLED DHAESEEric Veys

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

INTERLABORATORY VARIABILITY OF THE ANTIPERINUCLEAR FACTOR (APF) TEST FOR RHEUMATOID-ARTHRITIS.

TEW FELTKAMPJM BERTHELOTAMT BOERBOOMSHGM GEERTZENR HOETFilip De KeyserWJ VANVENROOIJG VERBRUGGENEric VeysP YOUINOU

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Rheumatoid nodules : differential diagnosis and immunohistological findings

Eric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

T cell receptor Vbeta usage in rheumatoid nodules - marked oligoclonality among DL-2 expanded lymphocytes.

Filip De KeyserG VERBRUGGENEric VeysClaude CuvelierAnne-Marie MalfaitDominique BenoitDirk ElewautJ VERMEERSCHA HEIRWEGH

A1 Journal Article in CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY

1992

INTERVENTION WITH IMMUNOMODULATORY AGENTS - NEW PHARMACOLOGICAL DEVELOPMENTS.

Eric VeysHerman MielantsG VERBRUGGENFilip De Keyser

A1 Journal Article in BAILLIERES CLINICAL RHEUMATOLOGY

Molecular concepts in the approach to therapy

Eric VeysHerman MielantsAugust VerbruggenFilip De Keyser

T-cell receptor expression in patients with rheumatic diseases

Filip De KeyserDominique BenoitDirk ElewautBart LeroyAnne-Marie MalfaitAugust VerbruggenEric Veys

T-cell receptor expression in patients with rheumatic diseases

Filip De KeyserDominique BenoitDirk ElewautBart LeroyAnne-Marie MalfaitAugust VerbruggenEric Veys

A1 Journal Article in PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

1989

Microgel diffusieblotting : toepassing van de techniek bij de evaluatie van de serologische antinucleaire immuniteit bij patiënten met reumatische aandoeningen

Filip De KeyserEric Veys

Prediction of diagnosis in patients with early arthritis using a modified Kohonen mapping in combination with a case based learning evaluation criterion

Luc BoullartS SETTEBart WynsDominique BaetenIlse HoffmanFilip De Keyser