Research Explorer

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Researcher

Fien Verhamme

Awards & Distinctions

29 Results

2023

RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD

Hannelore Van EeckhoutteChantal DonovanRichard Y. KimThomas M. ConlonMeshal AnsariHaroon KhanRanjith JayaramanNicole G. HansbroYves DondelingerTom Delanghe et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

2021

Epigenome-wide association study on diffusing capacity of the lung

Natalie TerzikhanHanfei XuAhmed Edris MohamedKen BrackeFien VerhammeBruno H. C. StrickerJosée DupuisLies LahousseGeorge T. O'ConnorGuy Brusselle

A1 Journal Article in ERJ OPEN RESEARCH

Necroptosis signalling promotes inflammation, airway remodelling and emphysema in COPD

Zhe LuHannelore Van EeckhoutteGang LiuPrema M NairBernadette JonesCaitlin GillisB. Christina NalkurthiFien VerhammeTamariche Buyle-HuybrechtPeter Vandenabeele et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Quantification and role of innate lymphoid cell subsets in Chronic Obstructive Pulmonary Disease

Evy BlommeSharen ProvoostElise De SmetKatrien De GroveHannelore Van EeckhoutteJoyceline De VolderPhilip M HansbroMatteo BonatoMarina SaettaSara Wijnant et al.

A1 Journal Article in CLINICAL & TRANSLATIONAL IMMUNOLOGY

2020

Innate lymphoid cells in isocyanate-induced asthma : role of microRNA-155

Evy BlommeSharen ProvoostErica BazzanHannelore Van EeckhoutteMirjam RoffelLore PollarisAnnelies BontinckMatteo BonatoLouise VandenbrouckeFien Verhamme et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

The myokine GDF-15 is a potential biomarker for myositis and associates with the protein aggregates of sporadic inclusion body myositis.

Boel De PaepeFien VerhammeJan De Bleecker

A1 Journal Article in Cytokine

The role of miR-155 in cigarette smoke-induced pulmonary inflammation and COPD

Elise De SmetHannelore Van EeckhoutteFrancisco Avila CobosEvy BlommeFien VerhammeSharen ProvoostSTIJN VERLEDENKoen VenkenTania MaesGuy Joos et al.

A1 Journal Article in MUCOSAL IMMUNOLOGY

2019

Bone morphogenetic protein 6 (BMP-6) modulates lung function, pulmonary iron levels and cigarette smoke-induced inflammation

Fien VerhammeElise De SmetWannes Van HoosteJoris DelangheSE VerledenGuy JoosGuy BrusselleKen Bracke

A1 Journal Article in MUCOSAL IMMUNOLOGY

Expression of receptor interacting protein kinase-3 and mixed lineage kinase domain-like protein in patients with COPD

Fien VerhammeHannelore Van EeckhoutteT Buyle-HuybrechtGuy BrussellePeter VandenabeeleTom Vanden BergheKen Bracke

GDF-15 in pulmonary and critical care medicine

Fien VerhammeChristine M FreemanGuy BrusselleKen BrackeJeffrey L Curtis

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Modulation of innate lymphoid cell subsets in a mouse model of isocyanate-induced asthma

Evy BlommeSarah ProvoostL PollarisHannelore Van EeckhoutteL VandenbrouckeFien VerhammeGuy JoosGuy BrusselleJ VanoirbeekTania Maes

Necroptosis is activated in and drives pathogenesis of COPD

M FrickerZ LuHannelore Van EeckhoutteG LiuFien VerhammeT Buyle-HuybrechtGuy BrusselleJ MurphyKen BrackeP Hansbro

2018

Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD

Elise De SmetLeen SeysFien VerhammeBart M VanaudenaerdeGuy BrusselleColin D BingleKen Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

DPP4, the Middle East respiratory syndrome coronavirus receptor, is upregulated in lungs of smokers and chronic obstructive pulmonary disease patients

Leen SeysW WidagdoFien VerhammeAlex KleinjanWim JanssensGuy JoosKen BrackeBart L HaagmansGuy Brusselle

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Heritability and genome-wide association study of diffusing capacity of the lung

Natalie TerzikhanFangui SunFien VerhammeHieab HH AdamsDaan LothKen BrackeBruno HC StrickerLies LahousseJosée DupuisGuy Brusselle et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

The role of microRNA-155 in cigarette smoke-induced inflammation

Elise De SmetPieter MestdaghFrancisco Avila CobosEvy BlommeFien VerhammeSharen ProvoostTania MaesGuy JoosGuy BrusselleKen Bracke

2017

Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure

Fien VerhammeLeen SeysElise De SmetSharen ProvoostW JanssensDirk ElewautGuy JoosGuy BrusselleKen Bracke

A1 Journal Article in MUCOSAL IMMUNOLOGY

Increased levels of enzymes involved in local estradiol synthesis in chronic obstructive pulmonary disease

GFJ KoningsNL ReynaertB DelvouxFien VerhammeKen BrackeGuy BrusselleA RomanoJHJ Vernooy

A1 Journal Article in MOLECULAR AND CELLULAR ENDOCRINOLOGY

MicroRNA profiling reveals a role for microRNA-218-5p in the pathogenesis of chronic obstructive pulmonary disease

Griet ConickxPieter MestdaghFrancisco Avila CobosFien VerhammeTania MaesBart M VanaudenaerdeLeen SeysLies LahousseRichard Y KimAlan C Hsu et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

2016

Characterization and quantification of innate lymphoid cell subsets in human lung

Katrien De GroveSharen ProvoostFien VerhammeKen BrackeGuy JoosTania MaesGuy Brusselle

A1 Journal Article in PLOS ONE

Microrna-218-5p is implicated in the pathogenesis of chronic obstructive pulmonary disease

Griet ConickxPieter MestdaghFrancisco Avila CobosFien VerhammeTania MaesBM VanaudenaerdeLies LahousseGuy JoosJo VandesompeleKen Bracke et al.

2015

Airway surface dehydration aggravates cigarette smoke-induced hallmarks of COPD in mice

Leen SeysFien VerhammeLisa DupontElke DesauterJulia DuerrAyca Seyhan AgircanGriet ConickxGuy JoosGuy BrusselleMarcus A Mall et al.

A1 Journal Article in PLOS ONE

Role of B cell-activating factor in chronic obstructive pulmonary disease

Leen SeysFien VerhammeAnja SchinwaldHamida HammadDanen Mootoosamy CunoosamyClaudie Bantsimba-MalandaAlan SabirshEileen McCallLiz FlavellRonald Herbst et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of lymphoid follicles and transforming growth factor (TGF)-β superfamily in the pathogenesis of chronic obstructive pulmonary disease (COPD)

Fien VerhammeGuy BrusselleKen Bracke

Transforming growth factor-β superfamily in obstructive lung diseases: more suspects than TGF-β alone

Fien VerhammeKen BrackeGuy JoosGuy Brusselle

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

2014

Cigarette smoke extract induces a phenotypic shift in epithelial cells: involvement of HIF1α in mesenchymal transition

Irene MJ EurlingsNiki L ReynaertTwan van den BeuckenHarry R GoskerCC de TheijeFien VerhammeKen BrackeEmiel FM WoutersMieke A Dentener

A1 Journal Article in PLOS ONE

Genome-wide association analysis identifies six new loci associated with forced vital capacity

Daan W LothMaria Soler ArtigasSina A GharibLouise V WainNora FranceschiniBeate KochTess D PottingerAlbert Vernon SmithQing DuanChris Oldmeadow et al.

A1 Journal Article in NATURE GENETICS

Role of activin-A in cigarette smoke-induced inflammation and COPD

Fien VerhammeKen BrackeGimano D AmatngalimGeert M VerledenGeert Van PottelbergePieter S HiemstraGuy JoosGuy Brusselle

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

2013

Role of CXCL13 in cigarette smoke-induced lymphoid follicle formation and chronic obstructive pulmonary disease

Ken BrackeFien VerhammeLeen SeysClaudie Bantsimba-MalandaDanen Mootoosamy CunoosamyRonald HerbstHamida HammadBart LambrechtGuy JoosGuy Brusselle

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE