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Researcher
Fien De Leersnyder
Profile
Projects
Publications
Activities
Awards & Distinctions
15
Results
2019
A Quality by Design strategy for a continuous pharmaceutical manufacturing process of tablets based on wet granulation
Fien De Leersnyder
Thomas De Beer
Eric Ziemons
Dissertation
2019
Evaluation of an in-line NIR spectroscopic method for the determination of the residence time in a tablet press
Fien De Leersnyder
Valérie Vanhoorne
Ashish Kumar
Chris Vervaet
Thomas De Beer
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2019
Modeling of semicontinuous fluid bed drying of pharmaceutical granules with respect to granule size
Michael Ghijs
Elisabeth Schäfer
Ashish Kumar
Philippe Cappuyns
Ivo Van Assche
Fien De Leersnyder
Valérie Vanhoorne
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL SCIENCES
2019
2018
Breakage and drying behaviour of granules in a continuous fluid bed dryer : influence of process parameters and wet granule transfer
Fien De Leersnyder
Valérie Vanhoorne
H Bekaert
Jurgen Vercruysse
Michael Ghijs
Nils Bostijn
Maxim Verstraeten
P Cappuyns
I Van Assche
Y Vander Heyden
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
2018
Development and validation of an in-line NIR spectroscopic method for continuous blend potency determination in the feed frame of a tablet press
Fien De Leersnyder
Elisabeth Peeters
Hasna Djalabi
Valérie Vanhoorne
Bernd Van Snick
Ke Hong
Stephen Hammond
Angela Yang Liu
Eric Ziemons
Chris Vervaet
et al.
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2018
Liquid-to-solid ratio control as an advanced process control solution for continuous twin-screw wet granulation
Niels Nicolaï
Fien De Leersnyder
Dana Copot
Michiel Stock
Clara-Mihaela Ionescu
Krist V Gernaey
Ingmar Nopens
Thomas De Beer
A1
Journal Article
in
AICHE JOURNAL
2018
2017
Multivariate statistical process control of a continuous pharmaceutical twin-screw granulation and fluid bed drying process
Ana Tavares da Silva
MC Sarraguça
Margot Fonteyne
Jurgen Vercruysse
Fien De Leersnyder
Valérie Vanhoorne
Nils Bostijn
Maxim Verstraeten
Chris Vervaet
Jean Paul Remon
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2017
2016
Blend uniformity evaluation during continuous mixing in a twin screw granulator by in-line NIR using a moving F-test
Margot Fonteyne
Jurgen Vercruysse
Fien De Leersnyder
Rut Besseling
Ad Gerich
Wim Oostra
Jean Paul Remon
Chris Vervaet
Thomas De Beer
A1
Journal Article
in
ANALYTICA CHIMICA ACTA
2016
Development of a controlled release formulation by continuous twin screw granulation : influence of process and formulation parameters
Valérie Vanhoorne
Brecht Vanbillemont
J Vercruysse
Fien De Leersnyder
P Gomes
Thomas De Beer
Jean Paul Remon
Chris Vervaet
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2016
Development of a process map : a step towards a regime map for steady-state high shear wet twin screw granulation
Ashish Kumar
Jens Dhondt
Jurgen Vercruysse
Fien De Leersnyder
Valérie Vanhoorne
Chris Vervaet
Jean Paul Remon
Krist V. Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
POWDER TECHNOLOGY
2016
Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation : an experimental investigation
Ashish Kumar
Maija Alakarjula
Valérie Vanhoorne
Maunu Toiviainen
Fien De Leersnyder
Jurgen Vercruysse
Mikko Juuti
Jarkko Ketolainen
Chris Vervaet
Jean Paul Remon
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
2016
Model-based process analysis in continuous manufacturing of pharmaceuticals : calibration of a fluid bed dryer model
Michael Ghijs
Fien De Leersnyder
Daan Van Hauwermeiren
Valérie Vanhoorne
Jurgen Vercruysse
Philippe Cappuyns
Séverine Mortier
Thomas De Beer
Krist Gernaey
Ingmar Nopens
C3
Conference
2016
2015
Development of regime map for steady-state high shear wet twin-screw granulation
Ashish Kumar
Jens Dhondt
Jurgen Vercruysse
Fien De Leersnyder
Valérie Vanhoorne
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2015
Evaluation of an in-line particle imaging tool for monitoring twin-screw granulation performance
Ashish Kumar
Jens Dhondt
Fien De Leersnyder
Jurgen Vercruysse
Valérie Vanhoorne
Chris Vervaet
Jean Paul Remon
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
POWDER TECHNOLOGY
2015
Process analytical technology for continuous manufacturing of solid-dosage forms
Margot Fonteyne
Jurgen Vercruysse
Fien De Leersnyder
Bernd Van Snick
Chris Vervaet
Jean Paul Remon
Thomas De Beer
A1
Journal Article
in
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
2015