Research Explorer

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Researcher

Eveline Verheugen

Awards & Distinctions

15 Results

2025

Intestinal epithelial expression of human TNF is sufficient to induce small bowel inflammation and sacroiliitis, mimicking human spondyloarthritis

Karlijn DebusschereDonald SouzaGerald H. NaboznyEmilie DumasEveline VerheugenJulie CoudenysTeddy ManuelloFlore StappersTine DecruyMargaux Maelegheer et al.

A1 Journal Article in RHEUMATOLOGY

2023

Gut inflammation in axial spondyloarthritis patients is characterized by a marked type 17 skewed mucosal innate‐like T cell signature

Céline MortierKatrien QuintelierAnn-Sophie De CraemerThomas RensonLiselotte DerooEmilie DumasEveline VerheugenJulie CoudenysTine DecruyZuzanna Łukasik et al.

A1 Journal Article in ARTHRITIS & RHEUMATOLOGY

2020

ER stress in antigen‐presenting cells promotes NKT cell activation through endogenous neutral lipids

Srinath GovindarajanEveline VerheugenKoen VenkenDjoere GaublommeMargaux MaelegheerEva ClootsFien GysensBruno De GeestTan‐Yun ChengD Branch Moody et al.

A1 Journal Article in EMBO REPORTS

2019

RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients

Koen VenkenPeggy JacquesCéline MortierMark E. LabadiaTine DecruyJulie CoudenysKathleen HoytAnita L. WayneRobert HughesMichael Turner et al.

A1 Journal Article in NATURE COMMUNICATIONS

2018

Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha

Srinath GovindarajanDjoere GaublommeRenée Van der CruyssenEveline VerheugenSofie Van GassenYvan SaeysSimon TavernierTakao IwawakiYehudi BlochSavvas Savvides et al.

A1 Journal Article in NATURE COMMUNICATIONS

2017

A20 inhibition of STAT1 expression in myeloid cells : a novel endogenous regulatory mechanism preventing development of enthesitis

Katelijne De WildeArne MartensStijn LambrechtPeggy JacquesMichael DrennanKarlijn DebusschereSrinath GovindarajanJulie CoudenysEveline VerheugenFien Windels et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Burden of hepatitis E virus infection in patients with rheumatic diseases

Peggy JacquesElizaveta PadalkoEveline VerheugenLien CattoirXavier VerhelstE NysS Van GuchtV HutseV SuinDirk Elewaut

2016

NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNF AIP3/A20

Michael DrennanSrinath GovindarajanEveline VerheugenJonathan CoquetJens StaalConor Mc GuireTom TaghonGeorges LeclercqRudi BeyaertGeert van Loo et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2015

Application of µCT in arthritis and osteoporosis research

Els LouagieIsabelle CambréAmélie De MuynckDjoere GaublommeElin PauwelsPieter VanderniepenFien WindelsJulie CoudenysNadia SchryversEveline Verheugen et al.

2014

A bidirectional crosstalk between iNKT cells and adipocytes mediated by leptin modulates susceptibility for T cell mediated hepatitis

Koen VenkenSylvie SeeuwsLennart ZabeauPeggy JacquesTine DecruyJulie CoudenysEveline VerheugenFien WindelsDominiek CatteeuwMichael Drennan et al.

A1 Journal Article in JOURNAL OF HEPATOLOGY

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

Lieselotte Vande WalleNina Van OpdenboschPeggy JacquesAmelie FossoulEveline VerheugenPeter VogelRudi BeyaertDirk ElewautThirumala-Devi KannegantiGeert van Loo et al.

A1 Journal Article in NATURE

Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells

Peggy JacquesStijn LambrechtEveline VerheugenElin PauwelsGeorge KolliasMaria ArmakaMarleen VerhoyeAnnemie Van der LindenEric AchtenRik J Lories et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

2011

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

Mourad MatmatiPeggy JacquesJonathan MaelfaitEveline VerheugenMirjam KoolMozes SzeLies GeboesEls LouagieConor Mc GuireLars Vereecke et al.

A1 Journal Article in NATURE GENETICS

A20 (TNFAIP3) deficiency in myeloid cells triggers rheumatoid arthritis

Dirk ElewautMourad MatmatiPeggy JacquesJonathan MaelfaitEveline VerheugenMirjam KoolMozes SzeLies GeboesEls LouagieConor Mc Guire et al.

2010

Biomechanical stretch is a key initiating event in the development of enthesitis in murine spondyloarthritis

Peggy JacquesStijn LambrechtEveline VerheugenRJ LoriesG KolliasAugust VerbruggenDirk Elewaut