Research Explorer

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Researcher

Eveline Verheugen

12 Results

2020

ER stress in antigen‐presenting cells promotes NKT cell activation through endogenous neutral lipids

Srinath GovindarajanEveline VerheugenKoen VenkenDjoere GaublommeMargaux MaelegheerEva ClootsFien GysensBruno De GeestTan‐Yun ChengD Branch MoodySophie JanssensMichael DrennanDirk Elewaut

A1 Journal Article in EMBO REPORTS

2019

RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients

Koen VenkenPeggy JacquesCéline MortierMark E. LabadiaTine DecruyJulie CoudenysKathleen HoytAnita L. WayneRobert HughesMichael TurnerSofie Van GassenLiesbet MartensDustin SmithChristian HarckenJoseph WahleChao-Ting WangEveline VerheugenNadia SchryversGaëlle VarkasHeleen CypersRuth WittoekYves PietteLieve GyselbrechtSerge Van CalenberghFilip Van den BoschYvan SaeysGerald NaboznyDirk Elewaut

A1 Journal Article in NATURE COMMUNICATIONS

2018

Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha

Srinath GovindarajanDjoere GaublommeRenée Van der CruyssenEveline VerheugenSofie Van GassenYvan SaeysSimon TavernierTakao IwawakiYehudi BlochSavvas SavvidesBart LambrechtSophie JanssensDirk ElewautMichael Drennan

A1 Journal Article in NATURE COMMUNICATIONS

2017

A20 inhibition of STAT1 expression in myeloid cells : a novel endogenous regulatory mechanism preventing development of enthesitis

Katelijne De WildeArne MartensStijn LambrechtPeggy JacquesMichael DrennanKarlijn DebusschereSrinath GovindarajanJulie CoudenysEveline VerheugenFien WindelsLeen CatrysseRik LoriesDennis McGonagleRudi BeyaertGeert van LooDirk Elewaut

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

2016

NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNF AIP3/A20

Michael DrennanSrinath GovindarajanEveline VerheugenJonathan CoquetJens StaalConor Mc GuireTom TaghonGeorges LeclercqRudi BeyaertGeert van LooBart LambrechtDirk Elewaut

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2015

Application of µCT in arthritis and osteoporosis research

Els LouagieIsabelle CambréAmélie De MuynckDjoere GaublommeElin PauwelsPieter VanderniepenFien WindelsJulie CoudenysNadia SchryversEveline VerheugenStijn LambrechtPeggy JacquesLuc Van HoorebekeDirk Elewaut

2014

A bidirectional crosstalk between iNKT cells and adipocytes mediated by leptin modulates susceptibility for T cell mediated hepatitis

Koen VenkenSylvie SeeuwsLennart ZabeauPeggy JacquesTine DecruyJulie CoudenysEveline VerheugenFien WindelsDominiek CatteeuwMichael DrennanSerge Van CalenberghBart LambrechtAkihiko YoshimuraJan TavernierDirk Elewaut

A1 Journal Article in JOURNAL OF HEPATOLOGY

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

Lieselotte Vande WalleNina Van OpdenboschPeggy JacquesAmelie FossoulEveline VerheugenPeter VogelRudi BeyaertDirk ElewautThirumala-Devi KannegantiGeert van LooMohamed Lamkanfi

A1 Journal Article in NATURE

Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells

Peggy JacquesStijn LambrechtEveline VerheugenElin PauwelsGeorge KolliasMaria ArmakaMarleen VerhoyeAnnemie Van der LindenEric AchtenRik J LoriesDirk Elewaut

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

2011

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

Mourad MatmatiPeggy JacquesJonathan MaelfaitEveline VerheugenMirjam KoolMozes SzeLies GeboesEls LouagieConor Mc GuireLars VereeckeYuanyuan ChuLouis BoonSteven StaelensPatrick MatthysBart LambrechtMarc Schmidt-SupprianManolis PasparakisDirk ElewautRudi BeyaertGeert van Loo

A1 Journal Article in NATURE GENETICS

A20 (TNFAIP3) deficiency in myeloid cells triggers rheumatoid arthritis

Dirk ElewautMourad MatmatiPeggy JacquesJonathan MaelfaitEveline VerheugenMirjam KoolMozes SzeLies GeboesEls LouagieConor Mc GuireLars VereeckeYuanyuan ChuSteven StaelensPatrick MatthysBart LambrechtMarc Schmidt-SupprianManolis PasparakisRudi BeyaertGeert van Loo

2010

Biomechanical stretch is a key initiating event in the development of enthesitis in murine spondyloarthritis

Peggy JacquesStijn LambrechtEveline VerheugenRJ LoriesG KolliasAugust VerbruggenDirk Elewaut