Research Explorer

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Researcher

Eva Malatinková

Awards & Distinctions

41 Results

2021

Measuring proviral HIV-1 DNA : hurdles and improvements to an assay monitoring integration events utilising human alu repeat sequences

Eva MalatinkováJordan ThomasWard De SpiegelaereSofie RutsaertAnna Maria GerettiGeorgios PollakisWilliam A. PaxtonLinos VandekerckhoveAlessandra Ruggiero

A1 Journal Article in LIFE-BASEL

2020

Underestimated effect of intragenic HIV-1 DNA methylation on viral transcription in infected individuals

Sam KintWim TrypsteenWard De SpiegelaereEva MalatinkováSabine Kinloch-de LoesTim De MeyerWim Van CriekingeLinos Vandekerckhove

A1 Journal Article in CLINICAL EPIGENETICS

2019

Decreased NEAT1 and MALAT1 levels in HIV-1 positive individuals with high viral load

Clarissa Van HeckeSabine Kinloch-de LoesTinus SchynkelEva MalatinkováKaren VervischSofie RutsaertWim Trypsteen

Decreased NEAT1 and MALAT1 levels in HIV-1 positive individuals with high viral load

Clarissa Van HeckeSabine Kinloch-de LoesTinus SchynkelEva MalatinkováKaren VervischSofie RutsaertWim TrypsteenLinos Vandekerckhove

Early treated HIV-1 positive individuals demonstrate similar restriction factor expression profile as long-term non-progressors

Clarissa Van HeckeWim TrypsteenEva MalatinkováWard De SpiegelaereKaren VervischSofie RutsaertSabine Kinloch-de LoesMagdalena SipsLinos Vandekerckhove

A1 Journal Article in EBIOMEDICINE

2018

Beneficial impact of early treatment on restriction factor expression profile

Clarissa Van HeckeWim TrypsteenEva MalatinkováWard De SpiegelaereKaren VervischMargaret JohnsonSabine Kinloch-de LoesMagdalena SipsLinos Vandekerckhove

Beneficial impact of early treatment on restriction factor expression profile

Clarissa Van HeckeMagdalena SipsEva MalatinkováWard De SpiegelaereKaren VervischMargaret JohnsonSabine Kinloch-de LoesWim TrypsteenLinos Vandekerckhove

2017

Beneficial impact of early treatment on restriction factor expression profile

Clarissa Van HeckeMagdalena SipsEva MalatinkováWard De SpiegelaereKaren VervischMargaret JohnsonSabine Kinloch-de LoesWim TrypsteenLinos Vandekerckhove

HIV integration sites in latently infected cell lines : evidence of ongoing replication

Jori SymonsAbha ChopraEva MalatinkováWard De SpiegelaereShay LearyDon CooperChike O AbanaAjantha RhodesSimin D RezaeiLinos Vandekerckhove et al.

A1 Journal Article in RETROVIROLOGY

HIV reservoir characterization symposium 19 September 2016, Ghent, Belgium

Eva MalatinkováWard De SpiegelaereLinos VandekerckhoveMagdalena Sips

A1 Journal Article in JOURNAL OF VIRUS ERADICATION

Highlights from the 24th conference on retroviruses and opportunistic infections, 13-16 February 2017, Seattle, Washington, USA

Trevor A CrowellHermione LyallEva MalatinkováSanjay BhaganiDenise HsuDonn J ColbyChristina PolyakChristina PsomasAndrew HillEsther N Gathogo et al.

A1 Journal Article in JOURNAL OF VIRUS ERADICATION

The expression profile of host restriction factors in different cohorts of HIV-1 infected patients

Clarissa Van HeckeEva MalatinkováMargaret JohnsonSabine Kinloch-de LoesWim TrypsteenLinos Vandekerckhove

Utility of integrated HIV-1 DNA quantification in cure studies

Alessandra RuggieroEva MalatinkováSofie RutsaertWilliam A PaxtonLinos VandekerckhoveWard De Spiegelaere

A1 Journal Article in FUTURE VIROLOGY

2016

Integrated and total HIV-1 DNA predict ex vivo viral outgrowth

Maja KiselinovaWard De SpiegelaereMaria Jose BuzonEva MalatinkováMathias LichterfeldLinos Vandekerckhove

A1 Journal Article in PLOS PATHOGENS

Modeling HIV-1 latency in primary T cells using a replication-competent virus

Laura MartinsPawel BonczkowskiAdam M SpivakWard De SpiegelaereCamille L NovisAna Beatriz DePaula-SilvaEva MalatinkováWim TrypsteenAlberto BosqueLinos Vandekerckhove et al.

A1 Journal Article in AIDS RESEARCH AND HUMAN RETROVIRUSES

Protein expression from unintegrated HIV-1 DNA introduces bias in primary in vitro post-integration latency models

Pawel BonczkowskiMarie-Angélique De ScheerderEva MalatinkováAlexandra BorchZora MelkovaRenate KoenigWard De SpiegelaereLinos Vandekerckhove

A1 Journal Article in SCIENTIFIC REPORTS

The long lasting impact of early treatment initiation on the size and dynamics of HIV-1 reservoirs

Eva MalatinkováLinos VandekerckhoveWard De Spiegelaere

Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection

Kristin HöhneRamona BusingerAnouk Van NuffelSebastian BolduanHerwig KoppensteinerAnn BaeyensJOLIEN VERMEIREEva MalatinkováBruno VerhasseltMichael Schindler

A1 Journal Article in OPEN BIOLOGY

2015

Accurate quantification of episomal HIV-1 two-long terminal repeat circles by use of optimized DNA isolation and droplet digital PCR

Eva MalatinkováMaja KiselinovaPawel BonczkowskiWim TrypsteenPeter MessiaenJOLIEN VERMEIREBruno VerhasseltKAREN VERVISCHLinos VandekerckhoveWard De Spiegelaere

A1 Journal Article in JOURNAL OF CLINICAL MICROBIOLOGY

Aviremia 10 years postdiscontinuation of antiretroviral therapy initiated during primary human immunodeficiency virus-1 infection and association with gag-specific T-cell responses

Sabine Kinloch-de LoesLucy DorellHongbing YangGareth AD HardySabine YerlyCristina CelleraiLinos VandekerckhoveWard De SpiegelaereEva MalatinkováWillie Wee Lee Koh et al.

A1 Journal Article in OPEN FORUM INFECTIOUS DISEASES

Comparison of methods for in-house screening of HLA*B57:01 to prevent abacavir hypersensitivity in HIV-1 care

Ward De SpiegelaereJan PhilippéKAREN VERVISCHChris VerhofstedeEva MalatinkováMaja KiselinovaWim TrypsteenPawel BonczkowskiDirk VogelaersSteven Callens et al.

A1 Journal Article in PLOS ONE

Comprehensive longitudinal characterization of HIV-1 reservoir markers in patients on stable antiretroviral treatment

Maja KiselinovaWard De SpiegelaereMaria Jose BuzonEva MalatinkováMathias LichterfeldLinos Vandekerckhove

Extreme value theory for threshold determination in droplet digital PCR experiments

Matthijs VynckWim TrypsteenJan De NevePawel BonczkowskiMaja KiselinovaEva MalatinkováKAREN VERVISCHOlivier ThasLinos VandekerckhoveWard De Spiegelaere

HIV-1 RNA and HIV-1 DNA persistence during suppressive ART with PI-based or nevirapine-based regimens

Maja KiselinovaAnna Maria GerettiEva MalatinkováKAREN VERVISCHApostolos BeloukasPeter MessiaenPawel BonczkowskiWim TrypsteenSteven CallensChris Verhofstede et al.

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

IAS towards an HIV cure Symposium : people focused, science driven 18-19 July 2015, Vancouver, Canada

Sarah FidlerJohn ThornhillEva MalatinkováRobert ReinhardRosanne LamploughJintanat AnanworanichAnn Chahroudi

A2 Journal Article in JOURNAL OF VIRUS ERADICATION

Impact of a decade of successful antiretroviral therapy initiated at HIV-1 seroconversion on blood and mucosal reservoirs

Eva MalatinkováWard De SpiegelaerePawel BonczkowskiMaja KiselinovaWim TrypsteenMargaret JohnsonChris VerhofstedeDanny De LoozeCharles MurraySabine Kinloch-de Loes et al.

A1 Journal Article in ELIFE

Impact of a decade of successful antiretroviral therapy started during HIV-1 seroconversion on blood and gut reservoirs

Sabine Kinloch-de LoesEva MalatinkováWard De SpiegelaerePawel BonczkowskiMaja KiselinovaKAREN VERVISCHWim TrypsteenMargaret JohnsonDanny De LoozeLinos Vandekerckhove

Integrated and total HIV-1 DNA can predict quantitative viral outgrowth in patients on long-term ART

Ward De SpiegelaereMaja KiselinovaMaria J BuzonEva MalatinkováMathias LichterfeldLinos Vandekerckhove

Integration site analysis of latently infected cell lines: evidence of ongoing replication

Jory SymonsSharon LewinAbha ChopraEva MalatinkováWard De SpiegelaereShay LearyDavid CooperLinos VandekerckhoveSimon MallalPaul Cameron

Long-term early antiretroviral therapy limits the HIV-1 reservoir size as compared to later treatment initiation but not to levels found in long-term non-progressors

Eva MalatinkováWard De SpiegelaerePawel BonczkowskiMaja KiselinovaKAREN VERVISCHWim TrypsteenMargaret JohnsonChris VerhofstedeDanny De LoozeCharles Murray et al.

Threshold determination in droplet digital PCR experiments using extreme value theory

Matthijs VynckWim TrypsteenJan De NevePawel BonczkowskiMaja KiselinovaEva MalatinkováKAREN VERVISCHOlivier ThasLinos VandekerckhoveWard De Spiegelaere

ddcRquant: threshold determination for single channel droplet digital PCR experiments

Wim TrypsteenMatthijs VynckJan De NevePawel BonczkowskiMaja KiselinovaEva MalatinkováKAREN VERVISCHOlivier ThasLinos VandekerckhoveWard De Spiegelaere

ddpcRquant: threshold determination for single channel droplet digital PCR experiments

Wim TrypsteenMatthijs VynckJan De NevePawel BonczkowskiMaja KiselinovaEva MalatinkováKAREN VERVISCHOlivier ThasLinos VandekerckhoveWard De Spiegelaere

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

2014

Accurate episomal HIV 2-LTR circles quantification using optimized DNA isolation and droplet digital PCR

Eva MalatinkováMaja KiselinovaPawel BonczkowskiWim TrypsteenPeter MessiaenJOLIEN VERMEIREBruno VerhasseltKaren VervischLinos VandekerckhoveWard De Spiegelaere

Quantification of integrated HIV DNA by repetitive-sampling Alu-HIV PCR on the basis of Poisson statistics

Ward De SpiegelaereEva MalatinkováLindsay LynchFilip Van NieuwerburghPeter MessiaenUna O'DohertyLinos Vandekerckhove

A1 Journal Article in CLINICAL CHEMISTRY

Replication competent virus as an important source of bias in HIV latency models utilizing single round viral constructs

Pawel BonczkowskiWard De SpiegelaereAlberto BosqueCory H WhiteAnouk Van NuffelEva MalatinkováMaja KiselinovaWim TrypsteenWojciech WitkowskiJOLIEN VERMEIRE et al.

A1 Journal Article in RETROVIROLOGY

The impact of nevirapine- versus protease inhibitor-based regimens on virological markers of HIV-1 persistence during seemingly suppressive ART

Maja KiselinovaMaria AnnaEva MalatinkováKAREN VERVISCHApostolos BeloukasPeter MessiaenPawel BonczkowskiWim TrypsteenSteven CallensChris Verhofstede et al.

2013

Droplet digital PCR, the new tool in HIV reservoir quantification?

Ward De SpiegelaereMaja KiselinovaEva MalatinkováAlexander PasternakBen BerkhoutLinos Vandekerckhove

Quantification of integrated HIV DNA by repetitive sampling Alu-HIV PCR and Poisson statistics

Ward De SpiegelaereEva MalatinkováFilip Van NieuwerburghUna O'DohertyLinos Vandekerckhove

Touchdown digital PCR for quantification of difficult amplicons in the HIV genome

Ward De SpiegelaereEva MalatinkováMaja KiselinovaPawel BonczkowskiChris VerhofstedeDirk VogelaersLinos Vandekerckhove

Touchdown digital polymerase chain reaction for quantification of highly conserved sequences in the HIV-1 genome

Ward De SpiegelaereEva MalatinkováMaja KiselinovaPawel BonczkowskiChris VerhofstedeDirk VogelaersLinos Vandekerckhove

A1 Journal Article in ANALYTICAL BIOCHEMISTRY