Research Explorer

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Researcher

Erwin Pannecoucke

Awards & Distinctions

6 Results

2022

The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement

Maximilian BrinkhausErwin PannecouckeElvera J. van der KooiArthur E. H. BentlageNinotska I. L. DerksenJulie AndriesBianca BalbinoMagdalena SipsPeter UlrichtsPeter Verheesen et al.

A1 Journal Article in NATURE COMMUNICATIONS

2021

Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting

Erwin PannecouckeMaaike Van TrimpontJohan DesmetTim PietersLindy ReunesLisa DemoenMarnik VuylstekeStefan LoverixKaren VandenbrouckePhilippe Alard et al.

A1 Journal Article in SCIENCE ADVANCES

Engineering and crystal structure of a monomeric FLT3 ligand variant

Erwin PannecouckeLaurens RaesSavvas Savvides

A1 Journal Article in ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS

2019

Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms

Benjamin H DurhamEstibaliz Lopez RodrigoJennifer PicarsicDavid AbramsonVeronica RotembergSteven De MunckErwin PannecouckeSydney X LuAlessandro PastoreAkihide Yoshimi et al.

A1 Journal Article in NATURE MEDICINE

An integrative approach towards unraveling the activation of oncogenic FLT3

Erwin PannecouckeSavvas Savvides

2013

Human IL-34 and CSF-1 establish structurally similar extracellular assemblies with their common hematopoietic receptor

Jan FélixJonathan ElegheertIrina GutscheAlexander ShkumatovYurong WenNathalie BrackeErwin PannecouckeIsabel VandenbergheBart DevreeseDmitri Svergun et al.

A1 Journal Article in STRUCTURE