Research Explorer

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Researcher

Elly De Vlieghere

Awards & Distinctions

53 Results

2023

A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment

Elly De VlieghereKoen Van de VijverEva BlondeelNathan CarpentierRouba GhobeiraJarne PauwelsSebastian RiemannManon MinsartCharlotte FieuwsJohanna Mestach et al.

A1 Journal Article in BIOMATERIALS RESEARCH

Increasing hydrogel complexity from 2D towards 3D towards intestinal tissue engineering

Anna SzabóElly De VliegherePedro F. CostaIndi GeursKoen DewettinckSandra Van Vlierberghe

A2 Journal Article in GIANT

Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts

Suzanne FischerDavid CreytensSofie De GeyterElly De VliegherePiet PattynSarah-Lee BekaertKaat DurinckNadine Van RoyAn HendrixLore Lapeire et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL MEDICINE

Volumetric printing of thiol‐ene photo‐cross‐linkable poly(ε‐caprolactone) : a tunable material platform serving biomedical applications

Quinten ThijssenAstrid QuaakJoseph ToombsElly De VlieghereLaurens ParmentierHayden TaylorSandra Van Vlierberghe

A1 Journal Article in ADVANCED MATERIALS

2022

Hybrid scaffolds as long-term in vitro co-culture model for targeted treatment of ovarian cancer

Elly De VlieghereEva BlondeelNathan CarpentierKoen Van de VijverSandra Van VlierbergheOlivier De Wever

Hybrid scaffolds to create long-term in vitro co-culture model for targeted treatment of ovarian cancer

Elly De VlieghereEva BlondeelNathan CarpentierKoen Van de VijverSandra Van VlierbergheOlivier De Wever

Metastasized orthotopic patient-derived xenografts as preclinical model to guide therapeutic decision making in soft tissue sarcoma patients

Suzanne FischerElly De VlieghereDavid CreytensOlivier De WeverAn HendrixLore LapeireGwen Sys

Preclinical platform for long-term evaluation of drug efficacy using three-dimensional tumor-stroma spheroids embedded in stiffness-tunable scaffolds

Elly De VlieghereEva BlondeelNathan CarpentierManon MinsartKoen Van de VijverSandra Van VlierbergheOlivier De Wever

2021

MISpheroID : a knowledgebase and transparency tool for minimum information in spheroid identity

Arne PeirsmanEva BlondeelTasdiq AhmedJasper AnckaertDominique AudenaertTom BoterbergKrisztina BuzasNeil CarragherGastone CastellaniFlávia Castro et al.

A1 Journal Article in NATURE METHODS

Tissue engineered hybrid scaffold with relevant stiffness and extracellular matrix (ECM) as long-term in vitro model for low-grade serous ovarian carcinoma (LGSOC)

Elly De VlieghereEva BlondeelNathan CarpentierSebastian RiemannWim CeelenSandra Van VlierbergheOlivier De Wever

2020

Localization and expression of nuclear factor of activated T-cells 5 in myoblasts exposed to pro-inflammatory cytokines or hyperosmolar stress and in biopsies from myositis patients

dr. Sandrine HerbeletElly De VlieghereAmanda GonçalvesBoel De PaepeKarsten SchmidtEline NysLaurens WeynantsJoachim WeisGert Van PeerJo Vandesompele et al.

Bookchapter in Myokines, adipokines, cytokines in muscle pathophysiology

Tumor engineered model for low-grade serous ovarian carcinoma (LGSOC) : mimicking the tumor environment on a cellular and biophysical level

Elly De VlieghereEva BlondeelWim CeelenBruno De GeestGeert BerxSandra Van VlierbergheOlivier De Wever

2019

Laser ablation-tandem ICP-mass spectrometry (LA-ICP-MS/MS) imaging of iron oxide nanoparticles in Ca-rich gelatin microspheres

Thibaut Van AckerEduardo Bolea FernandezElly De VlieghereJingxian GaoOlivier De WeverFrank Vanhaecke

A1 Journal Article in JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY

Tumor engineered model for peritoneal metastasis with controllable stiffness

Elly De VlieghereWim CeelenBruno De GeestHeidi DeclercqSandra Van VlierbergheOlivier De Wever

Tumor engineered scaffolds recapitulate a human peritoneal tumor environment at the cellular and biophysical level

Elly De VlieghereWim CeelenBruno De GeestHeidi DeclercqSandra Van VlierbergheOlivier De Wever

Tumor engineering a clinical relevant model that recapitulates the tumor environment of peritoneal metastases in vitro and in vivo

Elly De VlieghereEmiel De JaeghereGlenn WagemansThibaut Van AckerChristian VanhoveSarah NeytsGeert BerxFrank VanhaeckeWim CeelenBruno De Geest et al.

2018

Applications of laser ablation-inductively coupled plasma-mass spectrometry imaging in experimental peritoneal metastatic cancer research regarding tissue engineered biomaterials

Thibaut Van AckerElly De VlieghereEduardo Bolea FernandezOlivier De WeverFrank Vanhaecke

Glucocorticoids indirectly decrease colon cancer cell proliferation and invasion via effects on cancer-associated fibroblasts

Zuzanna DrebertElly De VlieghereJolien BridelanceOlivier De WeverKarolien De BosscherMarc BrackeIlse Beck

A1 Journal Article in EXPERIMENTAL CELL RESEARCH

Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo

Emiel De JaeghereElly De VlieghereJasper Van HoorickSandra Van VlierbergheGlenn WagemansLeen PietersElodie MelsensMarleen PraetJo Van DorpeMatthieu Boone et al.

A1 Journal Article in BIOMATERIALS

Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo

Olivier De WeverEmiel De JaeghereElly De Vlieghere

Hypoxia imaging with 18F-FAZA PET/CT predicts radiotherapy response in esophageal adenocarcinoma xenografts

Elodie MelsensElly De VlieghereBenedicte DescampsChristian VanhoveKen KersemansFilip De VosIngeborg GoethalsBoudewijn BransOlivier De WeverWim Ceelen et al.

A1 Journal Article in RADIATION ONCOLOGY

Localization and expression of nuclear factor of activated T-cells 5 in myoblasts exposed to pro-inflammatory cytokines or hyperosmolar stress and in biopsies from myositis patients

dr. Sandrine HerbeletElly De VlieghereAmanda GonçalvesBoel De PaepeKarsten SchmidtEline NysLaurens WeynantsJoachim WeisGert Van PeerJo Vandesompele et al.

A1 Journal Article in FRONTIERS IN PHYSIOLOGY

Radiotherapy-activated cancer-associated fibroblasts promote tumor progression through paracrine IGF1R activation

Joke TommeleinElly De VlieghereLaurine VersetElodie MelsensJustine LeendersBenedicte DescampsAnnelies DebucquoyChristian VanhovePatrick PauwelsChristian P Gespach et al.

A1 Journal Article in CANCER RESEARCH

Some diffuse large B cell lymphomas (DLBCLs) present with clone-dependent TTF-1 positivity

Mieke Van BockstalAlessandra CamboniElly De VlieghereFREDERIC DE RYCKAnn-Sophie CandaeleSOFIE GEENENLIES VANDEMAELEOlivier De WeverLouis LibbrechtSofie Verbeke et al.

A1 Journal Article in HISTOPATHOLOGY

Targeting Polo-like kinase 1 and TRAIL enhances apoptosis in non-small cell lung cancer

Alfiah NoorIjeoma Adaku UmeloPeter KronenbergerPhilipe GironElly De VlieghereOlivier De WeverErik TeugelsJacques De Grève

A2 Journal Article in ONCOTARGET

2017

ADAM-17/FHL2 colocalisation suggests interaction and role of these proteins in colorectal cancer

Laurine VersetJoke TommeleinChristine DecaesteckerElly De VlieghereMarc BrackeIsabelle SalmonOlivier De WeverPieter Demetter

A1 Journal Article in TUMOR BIOLOGY

Heterocellular 3D scaffolds as biomimetic of peritoneal metastases

Elly De VlieghereEmiel De JaeghereJasper Van HoorickGlenn WagemansLeen PietersElodie MelsensSara NeytBruno De GeestPeter DubruelWim Ceelen et al.

Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo

Elly De VlieghereEmiel De JaeghereJasper Van HoorickGlenn WagemansLeen PietersElodie MelsensSara NeytBruno De GeestPeter DubruelWim Ceelen et al.

Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo

Emiel De JaeghereElly De VlieghereJasper Van HoorickGlenn WagemansLeen PietersElodie MelsensSara NeytRouba GhobeiraRino MorentJo Van Dorpe et al.

Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo

Elly De VlieghereEmiel De JaeghereJasper Van HoorickGlenn WagemansLeen PietersElodie MelsensSara NeytBruno De GeestPeter DubruelWim Ceelen et al.

Improved xenograft efficiency of esophageal adenocarcinoma cell lines through in vivo selection

Elodie MelsensElly De VlieghereBenedicte DescampsChristian VanhoveOlivier De WeverWim CeelenPiet Pattyn

A1 Journal Article in ONCOLOGY REPORTS

In vivo visualisation of vessel formation in peritoneal tumour scaffolds with μCT

Emiel De JaeghereElly De VlieghereSara NeytBert VandeghinsteJasper Van HoorickGlenn WagemansLeen PietersElodie MelsensGeert BerxSandra Van Vlierberghe et al.

2016

Age and cellular context influence rectal prolapse formation in mice with caecal wall colorectal cancer xenografts

Joke TommeleinFélix GremonprezLaurine VersetElly De VlieghereGlenn WagemansChristian GespachTom BoterbergPieter DemetterWim CeelenMarc Bracke et al.

A1 Journal Article in ONCOTARGET

Dissemination and adhesion of peritoneal cancer cells to the peritoneal wall

Elly De VlieghereMarc BrackeLaurine VersetPieter DemetterOlivier De Wever

Bookchapter in Intraperitoneal cancer therapy : principles and practice

NFAT5 in Duchenne muscular dystrophy cultured myoblasts after exposure to hyperosmolar salt conditions

dr. Sandrine HerbeletAmanda GonçalvesElly De VlieghereGert Van PeerBoel De PaepeChris GuerinJo VandesompeleOlivier De WeverJan De Bleecker

NFAT5 in inflammatory myopathies and Duchenne muscular dystrophy

dr. Sandrine HerbeletAmanda GonçalvesElly De VlieghereBoel De PaepeChris GuerinOlivier De WeverJan De Bleecker

Preclinical activity of melflufen (J1) in ovarian cancer

Charlotte CarlierSara StreseKristina ViktorssonEbba VelanderPeter NygrenMaria UustaluTherese JunttiRolf LewensohnRolf LarssonJack Spira et al.

A1 Journal Article in ONCOTARGET

Quantitative evaluation of single cell spread on collagen matrices

Elly De VlieghereGlenn WagemansS De BackerZuzanna DrebertJoke TommeleinQuentin RousseauB WeynMarleen Van TroysMarc BrackeOlivier De Wever

A1 Journal Article in EXPERIMENTAL CELL RESEARCH

The core protein to myogenesis NFAT5 forms aggresomes in normal and Duchenne muscular dystrophy myotubes exposed to cell stressors

dr. Sandrine HerbeletElly De VlieghereAmanda GonçalvesBoel De PaepeChris GuerinOlivier De WeverJan De Bleecker

The core protein to myogenesis NFAT5 forms aggresomes in normal and Duchenne muscular dystrophy myotubes exposed to cell stressors

dr. Sandrine HerbeletElly De VlieghereGert Van PeerBoel De PaepeEline NysLaurens WeynantsJo VandesompeleOlivier De WeverJens SchmidtJan De Bleecker

2015

Addition of NaCl upregulates NFAT5 expression in Duchenne muscular dystrophy cultured myotubes

Laurens WeynantsEline Nysdr. Sandrine HerbeletBoel De PaepeElly De VlieghereLiselot MusLynn FeysOlivier De WeverJan De Bleecker

Biomimics of the peritoneal tumor-environment

Elly De VlieghereMarc BrackeJean Paul Remon

Cancer-associated fibroblasts as target and tool in cancer therapeutics and diagnostics

Elly De VlieghereLaurine VersetPieter DemetterMarc BrackeOlivier De Wever

A1 Journal Article in VIRCHOWS ARCHIV

Data on in vivo selection of SK-OV-3 Luc ovarian cancer cells and intraperitoneal tumor formation with low inoculation numbers

Elly De VlieghereCharlotte CarlierWim CeelenMarc BrackeOlivier De Wever

A2 Journal Article in DATA IN BRIEF

Impact of neoadjuvant therapy on cancer-associated fibroblasts in rectal cancer

Laurine VersetJoke TommeleinXavier Moles LopezChristine DecaesteckerTom BoterbergElly De VlieghereIsabelle SalmonMarcus MareelMarc BrackeOlivier De Wever et al.

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Stromal protein expression in breast cancer is differentially regulated by TGF-β1

Mieke Van BockstalKathleen LambeinMireille Van GeleElly De VlieghereRidha LimameGeert BraemsMarc BrackeHannelore DenysLouis LibbrechtOlivier De Wever

Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells

Elly De VlieghereFélix GremonprezLaurine VersetLore MariënChristopher JonesBram De CraeneGeert BerxBenedicte DescampsChristian VanhoveJean Paul Remon et al.

A1 Journal Article in BIOMATERIALS

2014

Bio-hybrid tumor cell-templated capsules: a generic formulation strategy for tumor associated antigens in view of immune therapy

Lien LybaertElly De VlieghereRiet De RyckeNane VanparijsOlivier De WeverStefaan De KokerBruno De Geest

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion

Mieke Van BockstalKathleen LambeinMireille Van GeleElly De VlieghereRIDHA LIMAMEGeert BraemsRudy Van den BroeckeVeronique CocquytHannelore DenysMarc Bracke et al.

A2 Journal Article in ONCOSCIENCE

Micro-particle encapsulated carcinoma-associated fibroblast (CAF) deceive and redirect disseminated cancer cells

Elly De VlieghereLaurine VersetChristian VanhoveLore MariënJean Paul RemonPieter DemetterMarc BrackeBruno De GeestOlivier De Wever

2013

CAF-encapsulated mico-particels capture free cancer cells from the peritoneal fluid

Elly De VlieghereLaurine VersetChristian VanhoveLore MariënJean Paul RemonPieter DemetterMarc BrackeBruno De GeestOlivier De Wever

Polysaccharide-based responsive nanogels for controlled drug delivery

Rachel Auzely-VeltyJing JingEmilie HachetDavid AlaimoElly De VlieghereAnna SzarpakChristine JeromeBruno De Geest

Tunable self-assembled nanogels composed of well-defined thermoresponsive hyaluronic acid-polymer conjugates

Jing JingDavid AlaimoElly De VlieghereChristine JérômeOlivier De WeverBruno De GeestRachel Auzély-Velty

A1 Journal Article in JOURNAL OF MATERIALS CHEMISTRY B