Research Explorer

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Researcher

Ellen Sanders

Publications & Research Data

Awards & Distinctions

32 Results

2026

RUVBL1 and RUVBL2 are druggable MYC effector regulators in neuroblastoma cells

Joachim SiawArne ClaeysWei-Yun LaiMarcus BorenäsElien HilgertSarah-Lee BekaertEllen SandersIrem KayaJo Van DorpeFranki Speleman et al.

A1 Journal Article in ISCIENCE

Targeting replication stress in neuroblastoma by exploiting the synergistic potential of second generation RRM2 and CHK1 inhibitors

Iris NelenSoetkin LeysSarah-Lee BekaertFanny De VloedFien MartensEllen SandersAngeline Praveena Enton RajAnnika JeschkeShunya OhmuraThomas G P Grünewald et al.

A1 Journal Article in CELL DEATH & DISEASE

2025

Second-generation AURKA-targeting PROTACs : structural optimization toward in vivo degradation in neuroblastoma

Simon KrolsMuhammad RishfiFien MartensAnouk Van HauwermeirenEllen SandersPieter-Jan De SutterAn VermeulenKaat De WeverSarah-Lee BekaertM. Emmy M. Dolman et al.

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Synergistic inhibition of CHK1 and MUS81 to combat replication stress resistance in high-risk neuroblastoma

Elien HilgertChristophe Van NesteSarah-Lee BekaertFien MartensSuzanne VanhauwaertEllen SandersPeter VerstraelenMartijn RisseeuwEllen M. WesterhoutMark A. Grannetia et al.

A1 Journal Article in SCIENTIFIC REPORTS

2023

SOX11 is a mediator of core regulatory circuit robustness : upregulation of SWI/SNF components and recruitment of transcriptional enhancer NONO

Amber LouwagieBieke DecaestekerSarah-Lee BekaertFanny De VloedEllen SandersStéphane Van HaverTim PietersPieter Van VlierbergheS RobertsS Ek et al.

Targeted AURKA degradation : towards new therapeutic agents for neuroblastoma

Muhammad RishfiSimon KrolsFien MartensSarah-Lee BekaertEllen SandersAline EggermontFanny De VloedJoshua Robert GouldingMartijn RisseeuwJan Molenaar et al.

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2022

Innovative mouse models for the tumor suppressor activity of protocadherin-10 isoforms

Irene KleinbergerEllen SandersKatrien StaesMarleen Van TroysShinji HiranoTino HochepiedKelly LemeireLiesbet MartensChristophe AmpeFrans Van Roy

A1 Journal Article in BMC CANCER

RRM2 enhances MYCN driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Lisa DepestelCarolina de Carvalho NunesLiselot MusIris NelenLouis DelhayeKaylee KellerVolodimir OlexioukFanny De VloedEllen SandersAline Eggermont et al.

RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Carolina de Carvalho NunesLisa DepestelLiselot MusKaylee M. KellerLouis DelhayeAmber LouwagieMuhammad RishfiAlex WhaleNeesha KaraSimon R. Andrews et al.

A1 Journal Article in SCIENCE ADVANCES

2021

Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions

Liselot MusStéphane Van HaverMina PopovicWim TrypsteenSteve LefeverNadja ZeltnerYudelca OgandoEva JacobsGeertrui DeneckerEllen Sanders et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

SOX11 as guardian of epigenetic plasticity in neuroblastoma

Bieke DecaestekerAmber LouwagieSiebe LoontiensSara De BrouwerCarolina de Carvalho NunesGeertrui DeneckerFanny De VloedLisa DepestelJuliette RoelsKaren Verboom et al.

2020

Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice

Tim PietersEllen SandersHuiyu TianJolanda van HengelFrans Van Roy

A1 Journal Article in BMC DEVELOPMENTAL BIOLOGY

2019

17q gain provides proliferative advantage to human embryonic stem cells under conditions of replicative stress

Liselot MusGeertrui DeneckerStéphane Van HaverNadja ZeltnerYudelca OgandoEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

17q gain provides proliferative advantage to human embryonic stem cells under replicative stress

Liselot MusStéphane Van HaverGeertrui DeneckerNadja ZeltnerYudelca OgandoEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

Armc8 is a evolutionarily conserved armadillo protein involved in cell-cell adhesion complexes through multiple molecular interactions

Ismail Sahin GülPaco HulpiauEllen SandersFrans Van RoyJolanda van Hengel

A1 Journal Article in BIOSCIENCE REPORTS

Exploring the contribution of gene dosage effects of 17q gain genes on hESC and neuroblastoma proliferation

Liselot MusGeertrui DeneckerStéphane Van HaverNadja ZeltnerYudelca OgandoEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

SOX11 as mediator of the adrenergic cell state in NB

Bieke DecaestekerAmber LouwagieSara De BrouwerVolodimir OlexioukGeertrui DeneckerCarolina de Carvalho NunesKaren VerboomMoritz GartlgruberWouter Van LoockeElena Afanasyeva et al.

SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

Amber LouwagieBieke DecaestekerCarolina de Carvalho NunesGeertrui DeneckerVolodimir OlexioukKaren VerboomMoritz GartlgruberWouter Van LoockeElena AfanasyevaPauline Depuydt et al.

SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

Amber LouwagieBieke DecaestekerSara De BrouwerGeertrui DeneckerCarolina de Carvalho NunesVolodimir OlexioukKaren VerboomMoritz GartlgruberWouter Van LoockeElena Afanasyeva et al.

2018

Exploring the contribution of gene dosage effects of 17q gain genes on hESC and neuroblastoma proliferation

Liselot MusGeertrui DeneckerStéphane Van HaverNadja ZeltnerYudelca OgandoEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

Exploring the contribution of gene dosage effects of 17q gain on ESC and neuroblastoma proliferation

Liselot MusGeertrui DeneckerNadja ZeltnerYudelca OgandoStéphane Van HaverEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

Exploring the contribution of gene dosage effects of 17Q gain on ESC and neuroblastoma proliferation

Liselot MusGeertrui DeneckerNadja ZeltnerYudelca OgandoStéphane Van HaverEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

Exploring the contribution of gene dosage effects of 17q gain on ESC and neuroblastoma proliferation

Liselot MusGeertrui DeneckerNadja ZeltnerYudelca OgandoStéphane Van HaverEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

GC content of Early Metazoan genes and its impact on gene expression levels in mammalian cell lines

Ismail Sahin GülJens StaalPaco HulpiauEvi De KeuckelaereKai KammTom DerooEllen SandersKatrien StaesYasmine DriegeYvan Saeys et al.

A1 Journal Article in GENOME BIOLOGY AND EVOLUTION

2015

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis

Tom Van NieuwenhuysenThomas NaertHong Tran ThiGriet Van ImschootSarah GeursEllen SandersDavid CreytensFrans Van RoyKris Vleminckx

A2 Journal Article in ONCOSCIENCE

2013

N-cadherin is required for cytodifferentiation during zebrafish odontogenesis

Barbara VerstraetenJolanda van HengelEllen SandersFrans Van RoyAnn Huysseune

A1 Journal Article in JOURNAL OF DENTAL RESEARCH

2012

Ocular anterior segment dysgenesis upon ablation of p120 catenin in neural crest cells

Huiyu TianEllen SandersAlbert ReynoldsFrans Van RoyJolanda van Hengel

A1 Journal Article in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Whole mount immunohistochemistry and in situ hybridization of larval and adult zebrafish dental tissues

Barbara VerstraetenEllen SandersAnn Huysseune

Bookchapter in Odontogenesis : methods and protocols

2011

Effects of p120ctm knockout in Wnt1 expressing cells on skull growth in mouse

Emilie DescampsEllen SandersHuiyu TianJolanda van HengelFrans Van RoyDominique Adriaens

2010

Expression pattern of E-cadherin during development of the first tooth in zebrafish (Danio rerio)

Barbara VerstraetenEllen SandersJolanda van HengelAnn Huysseune

A1 Journal Article in JOURNAL OF APPLIED ICHTHYOLOGY

Perturbations in the E-cadherin/catenin junctional complex in mouse embryos resulting in exencephaly

Emilie DescampsH TianEllen SandersJolanda van HengelFrans Van RoyDominique Adriaens

Zebrafish teeth as a model for repetitive epithelial morphogenesis: dynamics of E-cadherin expression

Barbara VerstraetenEllen SandersJolanda van HengelAnn Huysseune

A1 Journal Article in BMC DEVELOPMENTAL BIOLOGY