Research Explorer

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Researcher

Ellen De Paepe

Publications & Research Data

Awards & Distinctions

67 Results

2026

Chemical exposure in childhood : a study on organophosphate flame retardants and plasticizers in a Flemish birth cohort

Fatima den OudenAdam CseresznyeLiesa EngelenElias MarisStijn BosschaertsCeline GysPaulien CleysYu Ait BamaiRoger Peró GascónLieselot Hemeryck et al.

A1 Journal Article in ENVIRONMENTAL RESEARCH

Development and validation of an LC-MS/MS method for the simultaneous detection of urinary inflammatory biomarkers in a Flemish birth cohort

Fatima den OudenÁdám CseresznyeLiesa EngelenElias MarisEllen De PaepeGiulia PomaSebastian ProostArnau Vich i VilaLieselot HemeryckRoger Peró Gascón et al.

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

2025

A repository of the salivary metabolome and its key drivers in 1436 European children

Ellen De PaepeEmile CallemeynKimberly De WindtKathleen WijnantVera PlekhovaBeata PomianPablo VangeenderhuysenStefaan De HenauwNathalie MichelsHeli Viljakainen et al.

A1 Journal Article in EBIOMEDICINE

Alterations in gut‐derived uremic toxins before the onset of azotemic chronic kidney disease in cats

Laurens Van MuldersEllen Vanden BroeckeEllen De PaepeFemke MortierLynn VanhaeckeSylvie Daminet

A1 Journal Article in JOURNAL OF VETERINARY INTERNAL MEDICINE

Automated integration and quality assessment of chromatographic peaks in LC-MS data using TARDIS

Pablo VangeenderhuysenMatthijs VynckBeata PomianKimberly De WindtEmile CallemeynEllen De PaepeLindsey De CommerJeroen RaesTim NawrotJohannes Rainer et al.

Automated integration and quality assessment of chromatographic peaks in LC–MS-based metabolomics and lipidomics using TARDIS

Pablo VangeenderhuysenMatthijs VynckBeata PomianKimberly De WindtEmile CallemeynEllen De PaepeLindsey De CommerJeroen RaesTim NawrotJohannes Rainer et al.

A1 Journal Article in ANALYTICAL CHEMISTRY

Early detection of feline chronic kidney disease via 3-hydroxykynurenine and machine learning

Ellen Vanden BroeckeLaurens Van MuldersEllen De PaepeDominique PaepeSylvie DaminetLynn Vanhaecke

A1 Journal Article in SCIENTIFIC REPORTS

Exploring the salivary metabolome : key drivers and insights from 1,436 European children

Emile CallemeynEllen De PaepeLynn VanhaeckeVera PlekhovaKimberly De WindtMatthijs VynckPablo VangeenderhuysenNathalie MichelsAnja Geerts

Integrated fecal metabolomics and lipidomics via 2D-UHPLC-HRMS : a design of experiments approach

Tiffany De TroyerKimberly De WindtLieselot HemeryckEllen De PaepeVera PlekhovaLynn Vanhaecke

Metabolomics reveals alterations in gut-derived uremic toxins and tryptophan metabolism in feline chronic kidney disease

Laurens Van MuldersEllen Vanden BroeckeEllen De PaepeFemke MortierLynn VanhaeckeSylvie Daminet

A1 Journal Article in VETERINARY QUARTERLY

Robust metabolomics data normalization across scales and experimental designs

Matthijs VynckPablo VangeenderhuysenEllen De PaepeTim NawrotVera PlekhovaLynn Vanhaecke

The pediatric salivary metabolome : non-invasive insights into key drivers across 1,436 children

Emile CallemeynEllen De PaepeKimberly De WindtVera PlekhovaPablo VangeenderhuysenNathalie MichelsAnja GeertsMatthijs VynckLynn Vanhaecke

Towards automated integration and quality assessment of chromatographic peaks in targeted LC-MS data with TARDIS

Pablo VangeenderhuysenMatthijs VynckBeata PomianKimberly De WindtEmile CallemeynEllen De PaepeLindsey De CommerJeroen RaesTim MawrotJohannes Rainer et al.

Towards dual fecal metabolomics and lipidomics : design of experiments-driven optimization of biphasic extraction and two-dimensional UHPLC-HRMS

Kimberly De WindtVera PlekhovaTiffany De TroyerBeata PomianEllen De PaepeLynn Vanhaecke

Towards enhanced reproducibility and performance of quality control sample-based normalization : key issues and new ideas

Matthijs VynckPablo VangeenderhuysenEllen De PaepeLieselot HemeryckVera PlekhovaLynn Vanhaecke

2024

Determining the drivers of pediatric overweight and obesity : how does the salivary metabolome reflect children’s anthropometrics and dietary intake?

Emile CallemeynEllen De PaepePablo VangeenderhuysenNathalie MichelsStefaan De HenauwAnja GeertsLynn Vanhaecke

Determining the main drivers of childhood overweight and obesity using salivary metabolomics

Ellen De PaepeMarilyn De GraeveEmile CallemeynKathleen WijnantPablo VangeenderhuysenVera PlekhovaStefaan De HenauwNathalie MichelsMarja H. LeppänenTimo Lakka et al.

Determining the main drivers of childhood overweight and obesity with the salivary metabolome

Ellen De PaepeMarilyn De GraeveEmile CallemeynKathleen WijnantPablo VangeenderhuysenVera PlekhovaStefaan De HenauwNathalie MichelsMarja H. LeppänenTimo Lakka et al.

Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow's milk allergy

Ellen De PaepeVera PlekhovaPablo VangeenderhuysenNele BaeckDominique BullensTania ClaeysMarilyn De GraeveKristien KamoenAnneleen NotebaertTom Van de Wiele et al.

A1 Journal Article in ALLERGY

Optimization and validation of metabolomics methods for feline urine and serum towards application in veterinary medicine

Ellen Vanden BroeckeLaurens Van MuldersEllen De PaepeSylvie DaminetLynn Vanhaecke

A1 Journal Article in ANALYTICA CHIMICA ACTA

T.A.R.D.I.S. : Targeted Analysis and Raw Data Integration in Mass Spectrometry

Pablo VangeenderhuysenBeata PomianKimberly De WindtEmile CallemeynEllen De PaepeLieselot HemeryckLynn Vanhaecke

Towards biomarker discovery in feline CKD as a human disease model using validated urine and serum metabolomics

Ellen Vanden BroeckeLaurens Van MuldersEllen De PaepeSylvie DaminetLynn Vanhaecke

2023

A comprehensive metabolite fingerprint of fibrostenosis in patients with Crohn’s disease

Simon BosTriana Lobatón OrtegaMartine De VosSophie Van WeldenVera PlekhovaEllen De PaepeLynn VanhaeckeDebby Laukens

A1 Journal Article in SCIENTIFIC REPORTS

FLEXiGUT : investigating the importance of the exposome in the development and progression of chronic low-grade gut inflammation

Roger Peró GascónElias MarisÁdám CseresznyeFatima den OudenLiesa EngelenLieselot HemeryckEllen De PaepeArnau Vich VilaShirin MoossaviMuriel Derrien et al.

Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow’s milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveTom Van de WieleEric CoxLynn Vanhaecke

Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow’s milk allergy

Ellen De PaepeVera PlekhovaPablo VangeenderhuysenLars VereeckeMyriam Van WinckelMarilyn De GraeveTom Van de WieleEric CoxLynn Vanhaecke

Microbiome and metabolome dynamics during radiotherapy for prostate cancer

Willeke DanckaertMathieu SpaasNora SundahlAurélie De BruyckerValerie FonteyneEllen De PaepeCarlos De WagterLynn VanhaeckePiet Ost

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Urine and serum metabolomics as a diagnostic approach for early feline chronic kidney disease

Ellen Vanden BroeckeLaurens Van MuldersEllen De PaepeSylvie DaminetLynn Vanhaecke

Urine and serum metabolomics in veterinary medicine : towards early diagnosis of feline chronic kidney disease

Ellen Vanden BroeckeLaurens Van MuldersEllen De PaepeSylvie DaminetLynn Vanhaecke

2022

Electrospun nanofibrous samplers (MetaSAMP) provide superior biofluid metabolome stability and coverage following direct laser-assisted rapid evaporative ionization mass spectrometry

Vera PlekhovaMargot De SpiegeleerJozefien GeltmeyerBeata PomianVaroon SinghEllen De PaepeKathleen WijnantInge GiesNathalie MichelsMarilyn De Graeve et al.

Evaluation of potential thiamazole exposure of owners of orally treated hyperthyroid cats

Gaëlle SchilsEllen De PaepeBruno LapauwEllen Vanden BroeckeLaurens Van MuldersLynn VanhaeckeAurelie LyssensLisa StammeleerSylvie Daminet

A1 Journal Article in JOURNAL OF FELINE MEDICINE AND SURGERY

Integrating gut metabolomics and microbiomics towards biomarker discovery in pediatric cow’s milk allergy

Pablo VangeenderhuysenEllen De PaepeLieselot HemeryckMarilyn De GraeveLynn Vanhaecke

Integrating gut metabolomics and microbiomics towards biomarker discovery in pediatric cow’s milk allergy

Pablo VangeenderhuysenEllen De PaepeLieselot HemeryckMarilyn De GraeveLynn Vanhaecke

Metabolic pathways underlying cow's milk allergy in children : a metabolomics approach

Ellen De PaepeLynn VanhaeckeEric Cox

Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow's milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveTom Van de WieleEric CoxLynn Vanhaecke

Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow's milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveTom Van de WieleEric CoxLynn Vanhaecke

Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow's milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveEric CoxLynn Vanhaecke

Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow’s milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveTom Van de WieleEric CoxLynn Vanhaecke

Multi-omics data integration in pediatric cow’s milk allergy using DIABLO

Pablo VangeenderhuysenEllen De PaepeLieselot HemeryckMarilyn De GraeveLynn Vanhaecke

Novel lipidomic biomarker panel towards improving of diagnostic accuracy in pediatric cow's milk allergy

Vera PlekhovaEllen De PaepeLars VereeckeMyriam Van WinckelEric CoxLynn Vanhaecke

Towards a mouse model for studying food allergies from a metabolomics perspective : the case of pediatric cow’s milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveEric CoxLynn Vanhaecke

2021

A systematic review and pathway mapping of metabolic alterations underlying food allergy

Ellen De PaepeLynn Van GijseghemMargot De SpiegeleerEric CoxLynn Vanhaecke

A systematic review of metabolic alterations underlying IgE-mediated food allergy in children

Ellen De PaepeLynn Van GijseghemMargot De SpiegeleerEric CoxLynn Vanhaecke

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

Bacillus subtilis 29784 as a feed additive for broilers shifts the intestinal microbial composition and supports the production of hypoxanthine and nicotinic acid

Pearl ChoiLamya RhayatEric PinlocheEstelle DevillardEllen De PaepeLynn VanhaeckeFreddy HaesebrouckRichard DucatelleFilip Van ImmerseelEvy Goossens

A1 Journal Article in ANIMALS

Disparities in the gut metabolome of post-operative Hirschsprung's disease patients

Vera PlekhovaEllen De PaepeKatrien Van RenterghemMyriam Van WinckelLieselot HemeryckLynn Vanhaecke

A1 Journal Article in SCIENTIFIC REPORTS

Metabolic fingerprinting of feces from calves, subjected to gram-negative bacterial endotoxin

Saeid KameloroumiehAbbas Ali NaserianLieven Van MeulebroekEllen De PaepeReza ValizadehLynn Vanhaecke

A1 Journal Article in METABOLITES

Paediatric obesity : a systematic review and pathway mapping of metabolic alterations underlying early disease processes

Margot De SpiegeleerEllen De PaepeLieven Van MeulebroekInge GiesJean De SchepperLynn Vanhaecke

A1 Journal Article in MOLECULAR MEDICINE

Rapid ex vivo molecular fingerprinting of biofluids using laser-assisted rapid evaporative ionization mass spectrometry

Vera PlekhovaLieven Van MeulebroekMarilyn De GraeveAlvaro Perdones-MonteroMargot De SpiegeleerEllen De PaepeEmma Van de WalleZoltan TakatsSimon J. S. CameronLynn Vanhaecke

A1 Journal Article in NATURE PROTOCOLS

Study of the gut metabolome in postoperative Hirschsprung's disease patients hints at increased glycosaminoglycan breakdown and dysbiosis

Vera PlekhovaEllen De PaepeKatrien Van RenterghemMyriam Van WinckelLieselot HemeryckLynn Vanhaecke

2020

Multi-biofluid metabolomics as a tool to discover metabolite biomarkers for cow's milk allergy

Ellen De PaepeLieven Van MeulebroekVera PlekhovaMyriam Van WinckelEric CoxLynn Vanhaecke

2019

Fecal and multi-biofluid metabolomics as a tool to discover metabolite biomarkers for cow's milk allergy diagnosis

Ellen De PaepeEric CoxLynn Vanhaecke

Hydrophilic divinylbenzene for equilibrium sorption of emerging organic contaminants in aquatic matrices

Steve HuysmanFrancis VanryckeghemEllen De PaepeFoppe SmedesSimon A HaugheyChristopher T ElliottKristof DemeestereLynn Vanhaecke

A1 Journal Article in ENVIRONMENTAL SCIENCE & TECHNOLOGY

Metabolomics as a tool to discover metabolite biomarkers for cow milk allergy diagnosis

Ellen De PaepeLieven Van MeulebroekEric CoxLynn Vanhaecke

Multi-biofluid metabolomics as a tool to discover metabolite biomarkers for cow's milk allergy

Ellen De PaepeLieven Van MeulebroekVera PlekhovaMyriam Van WinckelEric CoxLynn Vanhaecke

Multi-biofluid metabolomics as a tool to discover metabolite biomarkers for cow's milk allergy diagnosis

Ellen De PaepeEric CoxLynn Vanhaecke

Ultra-high-performance liquid chromatography coupled to quadrupole orbitrap high-resolution mass spectrometry for multi-residue screening of pesticides, (veterinary) drugs and mycotoxins in edible insects

Ellen De PaepeJella WautersMik Van Der BorghtJohan ClaesSteve HuysmanSiska CroubelsLynn Vanhaecke

A1 Journal Article in FOOD CHEMISTRY

2018

A validated multi-matrix platform for metabolomic fingerprinting of human urine, feces and plasma using ultra-high performance liquid-chromatography coupled to hybrid orbitrap high-resolution mass spectrometry

Ellen De PaepeLieven Van MeulebroekCaroline RomboutsSteve HuysmanKaat VerplankenBruno LapauwJella WautersLieselot HemeryckLynn Vanhaecke

A1 Journal Article in ANALYTICA CHIMICA ACTA

Analysis of the Chemical Safety of Insect Consumption as Alternative for the Increasing Food Requirements

Ellen De PaepeJella WautersSiska CroubelsMik Van Der BorghtJohan ClaesLynn Vanhaecke

DNA adduct profiling of in vitro colonic meat digests to map red vs. white meat genotoxicity

Lieselot HemeryckCaroline RomboutsEllen De PaepeLynn Vanhaecke

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Multi-matrix biofluid metabolomics as a promising tool for biomarker discovery and pathway analysis

Ellen De PaepeLieven Van MeulebroekLynn Vanhaecke

The increasing prevalence of food allergies poses a huge thread to the world's wellbeing

Ellen De PaepeLieven Van MeulebroekEric CoxLynn Vanhaecke

2017

A validated ultra-high performance liquid chromatography coupled to high resolution mass spectrometry multi-matrix polar metabolomics fingerprinting platform

Ellen De PaepeLieven Van MeulebroekCaroline RomboutsSteve HuysmanKaat VerplankenLieselot HemeryckJella WautersBruno LapauwLynn Vanhaecke

DNA adduct profiling of in vitro meat digests as a means to assess red vs. white meat genotoxicity

Lieselot HemeryckCaroline RomboutsEllen De PaepeLynn Vanhaecke

Holistic lipidomics of the human gut phenotype using validated ultra-high-performance liquid chromatography coupled to hybrid orbitrap mass spectrometry

Lieven Van MeulebroekEllen De PaepeVicky VercruysseBeata PomianSimon BosBruno LapauwLynn Vanhaecke

A1 Journal Article in ANALYTICAL CHEMISTRY

Targeted, suspected and non-target screening with high resolution mass spectrometry in the marine environment : ready to go?

Steve HuysmanFrancis VanryckeghemLieven Van MeulebroekEllen De PaepeHerman Van LangenhoveKristof DemeestereLynn Vanhaecke

The use of a metabolomics platform to elucidate the relationship between the consumption of red meat and associated diseases

Caroline RomboutsLieselot HemeryckEllen De PaepeThomas Van HeckeStefaan De SmetWinnok De Vos

Ultra-high performance liquid chromatography coupled to quadrupole orbitrap high-resolution mass spectrometry for multi-residue screening of pesticides, (veterinary) drugs and mycotoxins in insects

Jella WautersEllen De PaepeEline KowalskiSiska CroubelsJohan ClaesLynn Vanhaecke