Research Explorer

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Researcher

Elke Rogge

Publications & Research Data

Awards & Distinctions

19 Results

2024

High efficacy of huCD20-targeted AcTaferon in humanized patient derived xenograft models of aggressive B cell lymphoma

Willem DaneelsAlexander Van ParysLeander HuygheElke RoggeSteffi De RouckRuben ChristiaenLennart ZabeauSylvie TaveirneJo Van DorpeNiko Kley et al.

A1 Journal Article in EXPERIMENTAL HEMATOLOGY & ONCOLOGY

2023

A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state

Sandra Van LintAlexander Van ParysBram Van Den EeckhoutNiels VandammeStephane PlaisanceAnnick VerheeDominiek CatteeuwElke RoggeJennifer De GeestNele Vanderroost et al.

A1 Journal Article in MOLECULAR CANCER

2019

A novel leptin receptor antagonist uncouples leptin’s metabolic and immune functions

Lennart ZabeauJoris WaumanJulie DamSandra Van LintElianne BurgJennifer De GeestElke RoggeAnisia SilvaRalf JockersJan Tavernier

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Targeting interferon activity to dendritic cells enables in vivo tolerization and protection against EAE in mice

Anje CauwelsSandra Van LintDominiek CatteeuwShengru PangFranciane PaulElke RoggeAnnick VerheeMarco PrinzNiko KleyGilles Uzé et al.

A1 Journal Article in JOURNAL OF AUTOIMMUNITY

2017

A safe and highly efficient tumor-targeted type I interferon immunotherapy depends on the tumor microenvironment

Anje CauwelsSandra Van LintGeneviève GarcinJennyfer BultinckFranciane PaulSarah GerloJosé Van Der HeydenYann BordatDominiek CatteeuwLode De Cauwer et al.

A1 Journal Article in ONCOIMMUNOLOGY

2015

Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice

Robrecht ThoonenAnje CauwelsKelly DecaluwéSandra GeschkaRobert E TainshJoris DelangheTino HochepiedLode De CauwerElke RoggeSofie Voet et al.

A1 Journal Article in NATURE COMMUNICATIONS

2014

A multiscale entropy-based tool for scoring severity of systemic inflammation

Benjamin VandendriesscheHarlinde PeperstraeteElke RoggePeter CauwelsEric HosteOliver StiedlPeter BrouckaertAnje Cauwels

A1 Journal Article in CRITICAL CARE MEDICINE

Extracellular ATP drives systemic inflammation, tissue damage and mortality

Anje CauwelsElke RoggeBenjamin VandendriesscheS ShivaPeter Brouckaert

A1 Journal Article in CELL DEATH & DISEASE

Heme-deficient NO-unresponsive sGC knock-in mice: novel aspects of NO sGC signaling in cardiovascular (patho)physiology

Robrecht ThoonenEmmanuel BuysAnje CauwelsKelly DecaluwéSandra GeschkaRobert TainshJoris DelangheTino HochepiedLode De CauwerElke Rogge et al.

2013

The soluble guanylate cyclase activator BAY 58-2667 protects against morbidity and mortality in endotoxic shock by recoupling organ systems

Benjamin VandendriesscheElke RoggeVera GoossensPeter VandenabeeleJohannes-Peter StaschPeter BrouckaertAnje Cauwels

A1 Journal Article in PLOS ONE

TLR2 activation causes no morbidity or cardiovascular failure, despite excessive systemic nitric oxide production

Anje CauwelsBenjamin VandendriesscheJennyfer BultinckBenedicte DescampsElke RoggeTom Van NieuwenhuysenMagdalena SipsChristian VanhovePeter Brouckaert

A1 Journal Article in CARDIOVASCULAR RESEARCH

2010

Reactive oxygen species and small-conductance calcium-dependent potassium channels are key mediators of inflammation-induced hypotension and shock

Anje CauwelsElke RoggeBen JanssenPeter Brouckaert

A1 Journal Article in JOURNAL OF MOLECULAR MEDICINE-JMM

2008

Gender-specific hypertension and responsiveness to nitric oxide in sGCα₁ knockout mice

Emmanuel BuysPatrick SipsPieter VermeerschMichael J RaherElke RoggeFumito IchinoseMieke DewerchinKenneth D BlochStefan JanssensPeter Brouckaert

A1 Journal Article in CARDIOVASCULAR RESEARCH

Phenotyping of NO-insensitive soluble guanylate cyclase beta1H105F Knockin mice

Peter BrouckaertRobrecht ThoonenEmmanuel BuysSofie NimmegeersElke RoggePatrick SipsKenneth D BlochJohan Van de Voorde

Targeting the NO-cGMP pathway: Phenotyping of NO-insensitive sGC beta 1 H105F knockin mice

Robrecht ThoonenM BUYSPatrick SipsElke RoggeT HOCHEPIEDSofie NimmegeersJV DE VOORDEP BROUCKAER

2006

Functional knockout of the soluble guanylate cyclase alpha 1 subunit leads to gender-specific hypertension while retaining sensitivity to nitric oxide

Patrick SipsE BUYSElke RoggeS NIMMEGEERSM DEWERCHINJ VAN DE VOORDEPeter Brouckaert

2005

Blood pressure in mice with a targeted deletion of the soluble guanylyl cyclase alpha 1 subunit

Peter BrouckaertE BUYSPatrick SipsElke RoggeM DEWERCHINAnje Cauwels

Functional knockout of the soluble guanylate cyclase alpha 1 subunit leads to gender-specific hypertension while retaining sensitivity to nitric oxide

Patrick SipsES BUYSElke RoggeM DEWERCHINPeter Brouckaert

2004

Gender-specific hypertension in mice deficient in the alpha(1) subunit of soluble guanylate cyclase

ES BUYSPatrick SipsElke RoggeM DEWERCHINPeter Brouckaert