Research Explorer

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Researcher

Elke Boone

Awards & Distinctions

19 Results

2007

Screening of indigenous Palestinian medicinal plants for potential anti-inflammatory and cytotoxic activity

Mary KailehWim Vanden BergheElke BooneT ESSAWIGuy Haegeman

A1 Journal Article in JOURNAL OF ETHNOPHARMACOLOGY

2006

Attenuation of mitogen- and stress-activated protein kinase-1-driven nuclear factor-kappa B gene expression by soy isoflavones does not require estrogenic activity

Wim Vanden BergheNathalie DijsselbloemLinda VermeulenMatladi NdlovuElke BooneGuy Haegeman

A1 Journal Article in CANCER RESEARCH

2001

Expression in Escherichia coli of the death domain of the human p55 tumor necrosis factor receptor.

Gert De WildeNico MertensElke BooneB DE VREESEJozef Van BeeumenWalter FiersGuy Haegeman

A1 Journal Article in PROTEIN EXPRESSION AND PURIFICATION

Structure-activity relationship of the p55 TNF receptor death domain and its lymphoproliferation mutants.

Gert De WildeJ MURRAY-RUSTElke BooneD OLERENSHAWNQ MCDONALDC IBANEZGuy HaegemanA WOLLMERM FEDERWISCH

A1 Journal Article in EUROPEAN JOURNAL OF BIOCHEMISTRY

2000

Glucocorticoids repress NF-kappa B-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell.

Karolien De BosscherW VANDEN BERGHELinda VermeulenS PLAISANCEElke BooneGuy Haegeman

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6.

Wim Vanden BergheLinda VermeulenGert De WildeKarolien De BosscherElke BooneGuy Haegeman

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

Structure/function analysis of p55 tumor necrosis factor receptor and Fas-associated death domain : effect on necrosis in L929sA cells.

Elke BooneTom Vanden BergheGeert van LooGert De WildeN DE WAELD VERCAMMENWalter FiersGuy HaegemanPeter Vandenabeele

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

1999

In search of the molecular mechanism of gene repression by glucocorticoids

Karolien De BosscherWim Vanden BergheElke BooneGuy Haegeman

In search of the molecular mechanism of gene repression by glucocorticoids.

Karolien De BosscherWim Vanden BergheElke BooneGuy Haegeman

Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: Inhibition of Cdc42-mediated filopodium formation by TNF.

M PEPPELENBOSCHElke BooneGE JONESSJH VAN DEVENTERGuy HaegemanWalter FiersJohan GrootenAJ RIDLEY

A1 Journal Article in JOURNAL OF IMMUNOLOGY

The nuclear factor-kappa B engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

Wim Vanden BergheKarolien De BosscherElke BooneS PLAISANCEGuy Haegeman

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

1998

Activation of p42/p44 mitogen-activated protein kinases (MAPK) and p38 MAPK by tumor necrosis factor (TNF) is mediated through the death domain of the 55-kDa TNF receptor.

Elke BooneVeronique VandevoordeGert De WildeGuy Haegeman

A1 Journal Article in FEBS LETTERS

Induction of unresponsiveness to tumor necrosis factor (TNF) after autocrine TNF expression requires TNF membrane retention.

Els DecosterB VANHAESEBROECKElke BooneS PLAISANCEKurt De VosGuy HaegemanJohan GrootenWalter Fiers

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region.

Kurt De VosVera GoossensElke BooneDominique VercammenK VANCOMPERNOLLEPeter VandenabeeleGuy HaegemanWalter FiersJohan Grooten

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor kappa B p65 transactivation mediated by tumor necrosis factor.

Wim Vanden BergheS PLAISANCEElke BooneKarolien De BosscherML SCHMITZWalter FiersGuy Haegeman

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

1997

Recombination signal sequence binding protein J kappa is constitutively bound to the NF-kappa B site of the interleukin-6 promoter and acts as a negative regulatory factor.

S PLAISANCEW VANDENBERGHEElke BooneWalter FiersGuy Haegeman

A1 Journal Article in MOLECULAR AND CELLULAR BIOLOGY

Tumour necrosis factor: intracellular mechanism of action

Walter FiersRudi BeyaertElke BooneWim DeclercqEls DecosterDirk De ValckVera GoossensJohan GrootenGuy HaegemanKaren Heyninck et al.

Bookchapter in HIV and cytokines

1996

TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.

Walter FiersRudi BeyaertElke BooneSigrid CornelisWim DeclercqEls DecosterGeertrui DeneckerBart DepuydtDirk De ValckG DEWILDE et al.

A1 Journal Article in JOURNAL OF INFLAMMATION

1993

Sensitization of tumor cells to tumor necrosis factor action by the protein kinase inhibitor staurosporine

Rudi BeyaertBart VanhaesebroeckKaren HeyninckElke BooneDirk De ValckKlaus Schulze-OsthoffGuy HaegemanFrans Van RoyWalter Fiers

A1 Journal Article in CANCER RESEARCH