Research Explorer

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Researcher

Elisabeth De Leeuw

Awards & Distinctions

18 Results

2024

Development of human innate immune responses in a humanized mouse model expressing four human myelopoiesis transgenes

Hannah StocksElisabeth De LeeuwBart LambrechtLinos VandekerckhoveGeert van LooAndy Wullaert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

The role of dendritic cells in respiratory viral infection

Elisabeth De LeeuwHamida Hammad

A1 Journal Article in EUROPEAN RESPIRATORY REVIEW

2023

A Complement Atlas identifies interleukin 6 dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Karel Van DammeLevi HosteJozefien DeclercqElisabeth De LeeuwBastiaan MaesLiesbet MartensRoos ColmanRobin BrowaeysCedric BosteelsStijn Verwaerde et al.

A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Karel Van DammeLevi HosteJozefien DeclercqElisabeth De LeeuwBastiaan MaesLiesbet MartensRoos ColmanRobin BrowaeysCedric BosteelsStijn Verwaerde et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

2022

Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19 : an open-label randomized controlled trial

Elisabeth De LeeuwKarel Van DammeJozefien DeclercqCedric BosteelsBastiaan MaesSimon TavernierLaurent DetalleTrevor SmartSophie GlattNincy Debeuf et al.

A1 Journal Article in RESPIRATORY RESEARCH

Inflammasomes and IL-1 family cytokines in SARS-CoV-2 infection : from prognostic marker to therapeutic agent

Jozefien DeclercqElisabeth De LeeuwBart Lambrecht

A1 Journal Article in CYTOKINE

Isolation of conventional murine lung dendritic cell subsets

Elisabeth De LeeuwCedric BosteelsBart LambrechtHamida Hammad

Bookchapter in Asthma : methods and protocols

Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment

Cedric BosteelsKarel Van DammeElisabeth De LeeuwJozefien DeclercqBastiaan MaesVictor BosteelsLevi HosteLeslie NaesensNincy DebeufJulie Deckers et al.

A1 Journal Article in CELL REPORTS MEDICINE

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Levi HosteLisa RoelsLeslie NaesensVictor BosteelsStijn VanheeSam DupontCedric BosteelsRobin BrowaeysNiels VandammeKevin Verstaen et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2021

Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19 : a meta-analysis

[missing] The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working GroupIsabel MurGracia María MateoMaria del Mar GutierrezVirginia PomarNatividad de BenitoNoemí CorbachoSilvia HerreraLucia MillanJessica Muñoz et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID) : a factorial, randomised, controlled trial

Jozefien DeclercqKarel Van DammeElisabeth De LeeuwBastiaan MaesCedric BosteelsSimon TavernierStefanie De BuyserRoos ColmanMaya HitesGil Verschelden et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

2020

Case report : convalescent plasma, a targeted therapy for patients with CVID and severe COVID-19

Karel Van DammeSimon TavernierNele Van RoyElisabeth De LeeuwJozefien DeclercqCedric BosteelsBastiaan MaesMarieke De BruyneDelfien BogaertVictor Bosteels et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC) : a structured summary of a study protocol for a randomised controlled trial

Cedric BosteelsBastiaan MaesKarel Van DammeElisabeth De LeeuwJozefien DeclercqANJA DELPORTEBENEDICTE DEMEYEREStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

A1 Journal Article in TRIALS

Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC) : a structured summary of a study protocol for a randomised controlled trial (vol 21, 491, 2020)

Cedric BosteelsBastiaan MaesKarel Van DammeElisabeth De LeeuwJozefien DeclercqAnja DelporteBenedicte DemeyereStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID) : a structured summary of a study protocol for a randomised controlled trial

Bastiaan MaesCedric BosteelsElisabeth De LeeuwJozefien DeclercqKarel Van DammeANJA DELPORTEBENEDICTE DEMEYEREStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

A1 Journal Article in TRIALS

Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID) : a structured summary of a study protocol for a randomised controlled trial (vol 21, 468, 2020)

Bastiaan MaesCedric BosteelsElisabeth De LeeuwJozefien DeclercqKarel Van DammeAnja DelporteBenedicte DemeyereStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV) : a structured summary of a study protocol for a randomised controlled trial

Jozefien DeclercqCedric BosteelsKarel Van DammeElisabeth De LeeuwBastiaan MaesAns VandecauterStefanie VermeerschAnja DelporteBénédicte DemeyereMarnik Vuylsteke et al.

A1 Journal Article in TRIALS

2019

Een ongewone oorzaak van een COPD-exacerbatie : herpetische tracheabronchitis

Elisabeth De LeeuwW VerhaegheB Vanden BergheI FabryK HertveldtGuy Joos

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE