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Researcher
Eline Pottie
Profile
Projects
Publications & Research Data
Activities
Awards & Distinctions
Patents
29
Results
2026
Live cell luminescence-based Gαq-PLC-β interaction assay : development and application at the serotonin 5-HT2A receptor
Eline Pottie
Christophe Stove
A1
Journal Article
in
PHARMACOLOGICAL RESEARCH
2026
Neuropharmacology of halogenated DMT analogs : psychoplastogenic and antidepressant properties of 5-Br-DMT, a psychedelic derivative with low hallucinogenic potential
Pol Puigseslloses
Nuria Nadal-Gratacos
Berta Fumas
Carlos Pablo Modenutti
Eline Pottie
Juan Rodrigo Ortigosa
Albert Pablo-Quesada
Clara Riera-Colomer
Miren Ettcheto
Xavier Berzosa
et al.
A1
Journal Article
in
MOLECULAR PSYCHIATRY
2026
The 4-alkyl chain length of 2,5-dimethoxyamphetamines differentially affects in vitro serotonin receptor actions versus in vivo psychedelic-like effects
Dino Luethi
Grant C. Glatfelter
Eline Pottie
Francesca Sellitti
Alexander D. Maitland
Nicholas R. Gonzalez
Lindsay A. Kryszak
Shelley N. Jackson
Marius C. Hoener
Christophe Stove
et al.
A1
Journal Article
in
MOLECULAR PSYCHIATRY
2026
The psychedelic phenethylamine 25C-NBF, a selective 5-HT2A agonist, shows psychoplastogenic properties and rapid antidepressant effects in male rodents
Nuria Nadal-Gratacos
Pol Puigseslloses
Laura Guzman
Nicola Weiss
Eline Pottie
Clara Riera-Colomer
Virginie Lardeux
Nathalie Thiriet
Fu-Hua Wang
Liselott Kallsten
et al.
A1
Journal Article
in
MOLECULAR PSYCHIATRY
2026
2025
Design, synthesis, and in vitro characterization of a tryptamine-based visible-light photoswitchable 5-HT2AR ligand showing efficacy preference for β-arrestin over mini-Gq
Alexandra Sink
Eline Pottie
Samuel J. Carter
Robert J. Tombari
Verena Weber
Paolo Carloni
Giulia Rossetti
David E. Olson
Christophe Stove
Michael Decker
A1
Journal Article
in
JOURNAL OF MEDICINAL CHEMISTRY
2025
Pain management beyond opioids : a β-arrestin2-biased allosteric GPCR modulator opens new avenues for drug development
Eline Pottie
Sophie A. M. Steinmüller
Michael Decker
Editorial material
2025
Synthesis, pharmacological characterization, and binding mode analysis of 8-hydroxy-tetrahydroisoquinolines as 5-HT7 receptor inverse agonists
Camilla B. Chan
Eline Pottie
Icaro A. Simon
Adrian G. Rossebø
Matthias M. Herth
Kasper Harpsøe
Jesper L. Kristensen
Christophe Stove
Christian B. M. Poulie
A1
Journal Article
in
ACS CHEMICAL NEUROSCIENCE
2025
2024
2-Substituted (N)-methanocarba A(3) adenosine receptor agonists : in silico, in vitro, and in vivo characterization
Dilip K. Tosh
Matteo Pavan
Chunxia Cronin
Eline Pottie
Tina C. Wan
Eric Chen
Sarah A. Lewicki
Ryan G. Campbell
Zhan-Guo Gao
John A. Auchampach
et al.
A2
Journal Article
in
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE
2024
Activity-based detection of synthetic cannabinoid receptor agonists in plant materials
Axelle Timmerman
Margot Balcaen
Vera Coopman
Maarten Degreef
Eline Pottie
Christophe Stove
A1
Journal Article
in
HARM REDUCTION JOURNAL
2024
Comparative pharmacological effects of lisuride and lysergic acid diethylamide revisited
Grant C. Glatfelter
Eline Pottie
John S. Partilla
Christophe Stove
Michael H. Baumann
A2
Journal Article
in
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE
2024
In vitro structure-activity relationships and forensic case series of emerging 2-benzylbenzimidazole 'nitazene' opioids
Liam De Vrieze
Sara E. Walton
Eline Pottie
Donna Papsun
Barry K. Logan
Alex J. Krotulski
Christophe Stove
Marthe Vandeputte
A1
Journal Article
in
ARCHIVES OF TOXICOLOGY
2024
Selective replacement of cholesterol with cationic amphiphilic drugs enables the design of lipid nanoparticles with improved RNA delivery
Bram Bogaert
Aliona Debisschop
Thomas Ehouarne
Hannelore Van Eeckhoutte
Joyceline De Volder
An Jacobs
Eline Pottie
Riet De Rycke
Aurélie Crabbé
Pieter Mestdagh
et al.
A1
Journal Article
in
NANO LETTERS
2024
2023
Assay-dependent inverse agonism at the A3 adenosine receptor : when neutral is not neutral
Eline Pottie
R. Rama Suresh
Kenneth A. Jacobson
Christophe Stove
A2
Journal Article
in
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE
2023
In vitro and in vivo evaluation of pellotine : a hypnotic lophophora alkaloid
Christian B. M. Poulie
Camilla B. Chan
Aleksandra Parka
Magnus Lettorp
Josephine Vos
Amanda Raaschou
Eline Pottie
Mikkel S. Bundgaard
Louis M. E. Sørensen
Claudia R. Cecchi
et al.
A2
Journal Article
in
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE
2023
Off-target activity of NBOMes and NBOMe analogs at the mu opioid receptor
Marie Deventer
Mattias Persson
Antonio Laus
Eline Pottie
Annelies Cannaert
Graziella Tocco
Henrik Green
Christophe Stove
A1
Journal Article
in
ARCHIVES OF TOXICOLOGY
2023
Structure-activity assessment and in-depth analysis of biased agonism in a set of phenylalkylamine 5‑HT2A receptor agonists
Eline Pottie
Christian B. M. Poulie
Icaro A. Simon
Kasper Harpsøe
Laura D'Andrea
Igor V. Komarov
David E. Gloriam
Anders A. Jensen
Jesper L. Kristensen
Christophe Stove
A1
Journal Article
in
ACS CHEMICAL NEUROSCIENCE
2023
2022
A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs
Bram Bogaert
Felix Sauvage
Roberta Guagliardo
Cristina Muntean
[missing] Van Phuc Nguyen
Eline Pottie
Mike Wels
An-Katrien Minnaert
Riet De Rycke
Qiangbing Yang
et al.
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2022
A(3) adenosine receptor agonists containing dopamine moieties for enhanced interspecies affinity
Dilip K. Tosh
Veronica Salmaso
Ryan G. Campbell
Harsha Rao
Amelia Bitant
Eline Pottie
Christophe Stove
Naili Liu
Oksana Gavrilova
Zhan-Guo Gao
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2022
An enlightening trip through psychedelic and purinergic signaling
Eline Pottie
Christophe Stove
Dissertation
2022
Discovery of ss-arrestin-biased 25CN-NBOH-derived 5-HT2A receptor agonists
Christian B. M. Poulie
Eline Pottie
Icaro A. Simon
Kasper Harpsoe
Laura D'Andrea
Igor V. Komarov
David E. Gloriam
Anders A. Jensen
Christophe Stove
Jesper L. Kristensen
A1
Journal Article
in
JOURNAL OF MEDICINAL CHEMISTRY
2022
Enlightening the 'spirit molecule' : photomodulation of the 5-HT2A receptor by a light-controllable N,N-dimethyltryptamine derivative
Hubert Gerwe
Feng He
Eline Pottie
Christophe Stove
Michael Decker
A1
Journal Article
in
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2022
The P2Y(2) receptor C-terminal tail modulates but is dispensable for beta-arrestin recruitment
Eline Pottie
Jolien Storme
Christophe Stove
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
2021
Serotonin 2A receptor (5-HT2AR) activation by 25H-NBOMe positional isomers : in vitro functional evaluation and molecular docking
Eline Pottie
Olga V. Kupriyanova
Asher L. Brandt
Robert B. Laprairie
Vadim A. Shevyrin
Christophe Stove
A2
Journal Article
in
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE
2021
Synthesis and functional characterization of 2-(2,5-dimethoxyphenyl)-N-(2-fluorobenzyl)ethanamine (25H-NBF) positional isomers
Eline Pottie
Olga V Kupriyanova
Vadim A. Shevyrin
Christophe Stove
A1
Journal Article
in
ACS CHEMICAL NEUROSCIENCE
2021
2020
Assessment of biased agonism at the A(3) adenosine receptor using beta-arrestin and miniG alpha(i) recruitment assays
Eline Pottie
Dilip K. Tosh
Zhan-Guo Gao
Kenneth A. Jacobson
Christophe Stove
A1
Journal Article
in
BIOCHEMICAL PHARMACOLOGY
2020
Identification of psychedelic new psychoactive substances (NPS) showing biased agonism at the 5-HT2AR through simultaneous use of beta-arrestin 2 and miniG alpha(q) bioassays
Eline Pottie
Peter Dedecker
Christophe Stove
A1
Journal Article
in
BIOCHEMICAL PHARMACOLOGY
2020
In vitro structure-activity relationship determination of 30 psychedelic new psychoactive substances by means of beta-arrestin 2 recruitment to the serotonin 2A receptor
Eline Pottie
Annelies Cannaert
Christophe Stove
A1
Journal Article
in
ARCHIVES OF TOXICOLOGY
2020
2019
Setup of a serotonin 2A receptor (5-HT2AR) bioassay : demonstration of its applicability to functionally characterize hallucinogenic new psychoactive substances and an explanation why 5-HT2AR bioassays are not suited for universal activity-based screening of biofluids for new psychoactive substances
Eline Pottie
Annelies Cannaert
Katleen Van Uytfanghe
Christophe Stove
A1
Journal Article
in
ANALYTICAL CHEMISTRY
2019
2017
In vitro and ex vivo delivery of tailored siRNA-nanoliposomes for E2F1 silencing as a potential therapy for colorectal cancer
Sabrina Bochicchio
Barbara Dapas
Ilaria Russo
Carolina Ciacci
Ornella Piazza
Stefaan De Smedt
Eline Pottie
Anna Angela Barba
Gabriele Grassi
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2017