Research Explorer

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Researcher

Elien Beyls

Publications & Research Data

Awards & Distinctions

19 Results

2025

Fibroblast-based radiosensitivity assays as a clinically valuable tool for (severe) combined immunodeficiency syndromes

Elien BeylsSomara De BeulVictoria BordonAlina FersterFilomeen HaerynckAnne VralAns Baeyens

A1 Journal Article in MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Investigating chromosomal radiosensitivity in inborn errors of immunity : insights from DNA repair disorders and beyond

Elien BeylsEvi DuthooLynn BackersKarlien Claes[missing] RAPID CliniciansTessa KerreB. LambrechtLevi HosteB. MeertensT. Van Genechten et al.

A1 Journal Article in JOURNAL OF CLINICAL IMMUNOLOGY

Replication stress, microcephalic primordial dwarfism, and compromised immunity in ATRIP deficient patients

Evi DuthooElien BeylsLynn BackersThorkell GudjónssonPeiquan HuangLeander JonckheereSebastian RiemannBram PartonLikun DuVeronique Debacker et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2024

Expanding molecular and clinical phenotype of Seckel syndrome : ATRIP deficient patient reveals novel insights in ATR signalling pathway

Kathleen ClaesLynn BackersElien BeylsEvi DuthooBram PartonVeronique DebackerKim De LeeneerMarieke De BruyneLevi HosteAns Baeyens et al.

Insights into radiosensitivity and defective DNA repair in immunodeficiency syndromes

Elien BeylsFilomeen HaerynckSimon Tavernier

The micronucleus assay on cryopreserved whole blood

Renu DayalElien BeylsAnne VralAns Baeyens

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

2022

A clinically annotated post-mortem approach to study multi-organ somatic mutational clonality in normal tissues

Tom LuijtsKerryn ElliottJoachim SiawJoris Van de VeldeElien BeylsArne ClaeysTim LammensErik LarssonWouter WillaertAnne Vral et al.

A1 Journal Article in SCIENTIFIC REPORTS

Fibroblast-based radiosensitivity assessment for primary immunodeficiency patients

Elien BeylsSomara De BeulFilomeen HaerynckVictoria BordonAlina FersterAnne VralAns Baeyens

2021

A novel non-coding variant in DCLRE1C results in deregulated splicing and induces SCID through the generation of a truncated ARTEMIS protein that fails to support V(D)J recombination and DNA damage repair

Steven StrubbeMarieke De BruyneUlrich PannickeElien BeylsBart VandekerckhoveGeorges LeclercqElfride De BaereVictoria BordonAnne VralKlaus Schwarz et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Cryopreserved whole blood and isolated peripheral blood mononuclear cells as alternative sample types for the cytokinesis-block micronucleus assay

Elien BeylsSimon SioenAns BaeyensAnne Vral

The cytokinesis-block micronucleus assay for cryopreserved whole blood

Elien BeylsAns BaeyensAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

The cytokinesis-block micronucleus assay on human cryopreserved whole blood and isolated peripheral blood mononuclear cells

Simon SioenElien BeylsAnne VralAns Baeyens

2020

Radiosensitivity assessment in fibroblasts from patients with a primary immunodeficiency

Elien BeylsAns BaeyensAnne Vral

Scaffold free microtissue formation for enhanced cartilage repair

Lise De MoorElien BeylsHeidi Declercq

A1 Journal Article in ANNALS OF BIOMEDICAL ENGINEERING

2019

Assessment of radiation sensitivity in patients with a primary immunodeficiency disease

Anne VralAns BaeyensKathleen ClaesCarolien BonroyVictoria BonroyElien BeylsEvi DuthooLynn BackersStephanie VermeulenFilomeen Haerynck

Development of an in vitro radiosensitivity assay on fibroblasts for patients with a primary immunodeficiency

Elien BeylsAns BaeyensAnne Vral

Radiosensitivity analysis in patients with a primary immunodeficiency disease

Anne VralAns BaeyensKathleen ClaesCarolien BonroyVictoria BordonElien BeylsEvi DuthooLynn BackersStephanie VermeulenFilomeen Haerynck

2017

Comparison of fibrochondrocyte and articular chondrocyte micro-aggregates for the future 3D-bioprinting of a fibrocartilage construct

Lise De MoorElien BeylsChris VercruysseHeidi Declercq

Histological evaluation of fibrochondrocyte and articular chondrocyte micro-aggregates for modular tissue engineering of fibrocartilage

Lise De MoorElien BeylsHeidi DeclercqMaria Cornelissen